Scholars@Duke
Cary Nobles Robertson

Cary Nobles Robertson

Associate Professor of Urology
Urology
cary.robertson@duke.edu
DUMC 3707, Durham, NC 27710
Box 3707 DUMC Rm 1572E Duke South, 40 Medicine Circle, Durham, NC 27710

Selected Publications

Primary Whole-gland Ablation for the Treatment of Clinically Localized Prostate Cancer: A Focal Therapy Society Best Practice Statement.

Journal Article Eur Urol · December 2023 CONTEXT: Whole-gland ablation is a feasible and effective minimally invasive treatment for localized prostate cancer (PCa). Previous systematic reviews supported evidence for favorable functional outcomes, but oncological outcomes were inconclusive owing t ... Full text Link to item Cite

Molecular biomarkers in the context of focal therapy for prostate cancer: recommendations of a Delphi Consensus from the Focal Therapy Society.

Journal Article Minerva Urol Nephrol · October 2022 BACKGROUND: Focal therapy (FT) for prostate cancer (PCa) is promising. However, long-term oncological results are awaited and there is no consensus on follow-up strategies. Molecular biomarkers (MB) may be useful in selecting, treating and following up men ... Full text Link to item Cite

Postoperative changes in cognition and cerebrospinal fluid neurodegenerative disease biomarkers.

Journal Article Ann Clin Transl Neurol · February 2022 OBJECTIVE: Numerous investigators have theorized that postoperative changes in Alzheimer's disease neuropathology may underlie postoperative neurocognitive disorders. Thus, we determined the relationship between postoperative changes in cognition and cereb ... Full text Open Access Link to item Cite

Available evidence on HIFU for focal treatment of prostate cancer: a systematic review.

Journal Article Int Braz J Urol · 2022 PURPOSE: Prostate cancer (PCa) is the second most common oncologic disease among men. Radical treatment with curative intent provides good oncological results for PCa survivors, although definitive therapy is associated with significant number of serious s ... Full text Link to item Cite

Perioperative neurocognitive and functional neuroimaging trajectories in older APOE4 carriers compared with non-carriers: secondary analysis of a prospective cohort study.

Journal Article Br J Anaesth · December 2021 BACKGROUND: Cognitive dysfunction after surgery is a major issue in older adults. Here, we determined the effect of APOE4 on perioperative neurocognitive function in older patients. METHODS: We enrolled 140 English-speaking patients ≥60 yr old scheduled fo ... Full text Open Access Link to item Cite

Immunomodulatory lipid mediator profiling of cerebrospinal fluid following surgery in older adults.

Journal Article Sci Rep · February 4, 2021 Arachidonic acid (AA), docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA) derived lipids play key roles in initiating and resolving inflammation. Neuro-inflammation is thought to play a causal role in perioperative neurocognitive disorders, yet th ... Full text Open Access Link to item Cite

Cerebrospinal Fluid Proteome Changes in Older Non-Cardiac Surgical Patients with Postoperative Cognitive Dysfunction.

Journal Article J Alzheimers Dis · 2021 BACKGROUND: Postoperative cognitive dysfunction (POCD), a syndrome of cognitive deficits occurring 1-12 months after surgery primarily in older patients, is associated with poor postoperative outcomes. POCD is hypothesized to result from neuroinflammation; ... Full text Open Access Link to item Cite

A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.

Journal Article J Neurol · July 2020 OBJECTIVE: Lumbar punctures (LPs) are important for obtaining CSF in neurology studies but are associated with adverse events and feared by many patients. We determined adverse event rates and pain scores in patients prospectively enrolled in two cohort st ... Full text Link to item Cite

The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is the A ... Full text Open Access Link to item Cite

Flow Cytometry Characterization of Cerebrospinal Fluid Monocytes in Patients With Postoperative Cognitive Dysfunction: A Pilot Study.

Journal Article Anesth Analg · November 2019 Animal models suggest postoperative cognitive dysfunction may be caused by brain monocyte influx. To study this in humans, we developed a flow cytometry panel to profile cerebrospinal fluid (CSF) samples collected before and after major noncardiac surgery ... Full text Open Access Link to item Cite

Illness uncertainty, partner support, and quality of life: A dyadic longitudinal investigation of couples facing prostate cancer.

Journal Article Psychooncology · November 2019 OBJECTIVE: Prostate cancer (PC) and its treatment often result in chronic, negative side-effects that affect both patients and their romantic partners. Illness uncertainty is a chronic stressor that impacts PC patients and their partners and, if left unman ... Full text Link to item Cite

Evaluation and Active Treatment versus Active Surveillance of Localized Prostate Cancer in Renal Transplant Patients in the Era of Low and Very Low Risk Prostate Cancer.

Journal Article J Urol · September 2019 PURPOSE: Current trends in renal transplantation, such as improved allograft/recipient survival and expanded organ transplantation eligibility criteria in older recipients, are concomitant with increasingly detected low risk prostate cancer in candidates f ... Full text Link to item Cite

Patient selection for prostate focal therapy in the era of active surveillance: an International Delphi Consensus Project.

Journal Article Prostate Cancer Prostatic Dis · September 2017 BACKGROUND: Whole-gland extirpation or irradiation is considered the gold standard for curative oncological treatment for localized prostate cancer, but is often associated with sexual and urinary impairment that adversely affects quality of life. This has ... Full text Link to item Cite

Salvage high-intensity focused ultrasound (HIFU) for locally recurrent prostate cancer after failed radiation therapy: Multi-institutional analysis of 418 patients.

Journal Article BJU Int · June 2017 OBJECTIVE: To report the oncological outcome of salvage high-intensity focused ultrasound (S-HIFU) for locally recurrent prostate cancer after external beam radiotherapy (EBRT) from a multicentre database. PATIENTS AND METHODS: This retrospective study com ... Full text Link to item Cite

High-intensity focused ultrasound for focal therapy: reality or pitfall?

Journal Article Curr Opin Urol · March 2017 PURPOSE OF REVIEW: Progress in imaging, fusion software, and ablative modalities has fostered growth of the latest image-guided generation of high-intensity focused ultrasound (HIFU) for focal treatment of prostate cancer. Although early reports are encour ... Full text Link to item Cite

Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults.

Journal Article Front Syst Neurosci · 2017 Each year over 16 million older Americans undergo general anesthesia for surgery, and up to 40% develop postoperative delirium and/or cognitive dysfunction (POCD). Delirium and POCD are each associated with decreased quality of life, early retirement, incr ... Full text Open Access Link to item Cite

Effects of physical and mental health on relationship satisfaction: a dyadic, longitudinal examination of couples facing prostate cancer.

Journal Article Psychooncology · August 2016 OBJECTIVES: Prostate cancer may affect quality of life in men diagnosed as well as their spouses. Changes in health may disrupt the couple's relationship functioning which disrupts recovery. This study examined how mental and physical health relates to rel ... Full text Link to item Cite

Follow-up modalities in focal therapy for prostate cancer: results from a Delphi consensus project.

Journal Article World J Urol · October 2015 INTRODUCTION: Focal therapy can offer the middle ground for treatment between active surveillance and radical therapy in patients with low- and intermediate-risk prostate cancer. Factors that prohibit focal therapy from being standard of care are numerous. ... Full text Link to item Cite

Psychosocial trajectories of men monitoring prostate-specific antigen levels following surgery for prostate cancer.

Journal Article Oncol Nurs Forum · July 1, 2014 PURPOSE/OBJECTIVES: To describe the psychosocial trajectories of men treated surgically for prostate cancer after monitoring their prostate-specific antigen (PSA) levels until 24 months post-treatment. DESIGN: Descriptive longitudinal study. SETTING: Urolo ... Full text Link to item Cite

Low central venous pressure versus acute normovolemic hemodilution versus conventional fluid management for reducing blood loss in radical retropubic prostatectomy: a randomized controlled trial.

Journal Article Curr Med Res Opin · May 2014 OBJECTIVE: To compare acute normovolemic hemodilution versus low central venous pressure strategy versus conventional fluid management in reducing intraoperative estimated blood loss, hematocrit drop and need for blood transfusion in patients undergoing ra ... Full text Link to item Cite

Sexual bother and function after radical prostatectomy: predictors of sexual bother recovery in men despite persistent post-operative sexual dysfunction.

Journal Article Andrology · March 2013 Changes in sexual bother (SB) following radical prostatectomy (RP) negatively affect health-related quality of life (HRQoL) of prostate cancer survivors. However, post-operative SB tends to be neglected whereas sexual function (SF) is thoroughly assessed i ... Full text Link to item Cite

Complete high-intensity focused ultrasound in prostate cancer: outcome from the @-Registry.

Journal Article Prostate Cancer Prostatic Dis · September 2012 Featured Publication BACKGROUND: To analyze data on patients with localized prostate cancer who were treated with complete high-intensity focused ultrasound (HIFU) prospectively captured within a voluntary HIFU user database (@-Registry). METHODS: The @-Registry includes data ... Full text Link to item Cite

The number of high-risk factors and the risk of prostate cancer-specific mortality after brachytherapy: implications for treatment selection.

Journal Article Int J Radiat Oncol Biol Phys · April 1, 2012 Featured Publication PURPOSE: To determine whether an increasing number of high-risk factors is associated with higher prostate cancer-specific mortality (PCSM) among men treated with brachytherapy (BT)-based treatment, and whether supplemental therapy has an impact on this ri ... Full text Link to item Cite

Perineural versus lymphovascular invasion: Which is a better marker for unfavorable biochemical outcomes following prostatectomy? Results from the Duke Prostate Center Database.

Journal Article J Clin Oncol · February 10, 2012 34 Background: Despite a substantial effort to study the clinical significance of perineural invasion in prostate biopsies (PNIb) its prognostic significance remains controversial. The limited data on perineural invasion in radical prostatectomy (RP) speci ... Link to item Cite

Perineural versus lymphovascular invasion: Which is a better marker for unfavorable biochemical outcomes following prostatectomy? Results from the Duke Prostate Center Database.

Journal Article J Clin Oncol · February 10, 2012 34 Background: Despite a substantial effort to study the clinical significance of perineural invasion in prostate biopsies (PNIb) its prognostic significance remains controversial. The limited data on perineural invasion in radical prostatectomy (RP) speci ... Full text Link to item Cite

M-HIFU inhibits tumor growth, suppresses STAT3 activity and enhances tumor specific immunity in a transplant tumor model of prostate cancer.

Journal Article PLoS One · 2012 OBJECTIVE: In this study, we explored the use of mechanical high intensity focused ultrasound (M-HIFU) as a neo-adjuvant therapy prior to surgical resection of the primary tumor. We also investigated the role of signal transducer and activator of transcrip ... Full text Open Access Link to item Cite

Utilization trends at a multidisciplinary prostate cancer clinic: initial 5-year experience from the Duke Prostate Center.

Journal Article J Urol · January 2012 Featured Publication PURPOSE: The multidisciplinary approach is becoming increasingly encouraged but little is known about the multidisciplinary experience compared to routine care. For patients with prostate cancer the goal is to provide evaluations by urologists, medical and ... Full text Link to item Cite

HIFU as a neoadjuvant therapy in cancer treatment

Other AIP Conference Proceedings · October 13, 2011 To broaden the application spectrum of HIFU in cancer therapy, we performed a pilot experiment to evaluate the potential of using HIFU as a neoadjuvant therapy prior to surgery. Mice bearing wild-type B16F10 melanoma inoculated subcutaneously were either u ... Full text Cite

Factors predicting early and late phase decline of sexual health-related quality of life following radical prostatectomy.

Journal Article J Sex Med · October 2011 Featured Publication INTRODUCTION: The association between early and late phase sexual health-related quality of life (HRQoL) following radical prostatectomy (RP) is unclear. Moreover, factors that predict either early or late sexual HRQoL decline have not been fully investiga ... Full text Link to item Cite

Correlation of prostate-specific antigen nadir and biochemical failure after high-intensity focused ultrasound of localized prostate cancer based on the Stuttgart failure criteria - analysis from the @-Registry.

Journal Article BJU Int · October 2011 Featured Publication OBJECTIVE: •To determine if the prostate-specific antigen (PSA) nadir after high-intensity focused ultrasound (HIFU) can be used as a predictor of the biochemical disease-free survival rate (DFSR). PATIENTS AND METHODS: •Patient data were derived from the ... Full text Link to item Cite

3D Conformal and Intensity Modulated Radiotherapy to the Prostate Bed have Similar Biochemical Outcomes

Conference International Journal of Radiation Oncology*Biology*Physics · October 2011 Full text Cite

Neoadjuvant Radiotherapy plus Prostatectomy for High Risk Prostate Cancer

Conference International Journal of Radiation Oncology*Biology*Physics · October 2011 Full text Cite

Kidney cancer.

Journal Article J Natl Compr Canc Netw · September 1, 2011 Featured Publication Full text Link to item Cite

Salvage radiation in men after prostate-specific antigen failure and the risk of death.

Journal Article Cancer · September 1, 2011 Featured Publication BACKGROUND: A survival benefit has been observed with salvage radiation therapy (RT) for prostate-specific antigen (PSA) failure after radical prostatectomy (RP) in men with rapid rises in PSA doubling time (DT, < 6 months). Whether such a benefit exits in ... Full text Link to item Cite

Prostate-specific antigen velocity based risk-adapted discontinuation of prostate cancer screening in elderly men.

Journal Article BJU Int · July 2011 Featured Publication OBJECTIVE: • To evaluate weather prostate-specific antigen (PSA) velocity could be used to stratify patients at risk of death from prostate cancer (PCa) and be useful in aiding decision making regarding PSA screening in elderly men, as previous studies hav ... Full text Link to item Cite

Abstract 2767: Genetic variation in obesity-related genes ADBR2, ADBR3, GHRL, HSD11B1, and SHC1 and risk of prostate cancer: A VA case-control study

Journal Article Cancer Research · April 15, 2011 AbstractINTRODUCTION: Single nucleotide polymorphisms (SNPs) are single nucleotide variations that occur within alleles among individuals. It is believed that SNPs may predispose a person to diseases such as ... Full text Cite

Clinical predictors of renal mass pathological features.

Journal Article BJU Int · March 2011 Featured Publication OBJECTIVE: • To evaluate the influence of radiographic tumour size and other preoperative variables on the pathological characteristics of the lesion to determine the distribution of pathological features and assess preoperative risk factors for potentiall ... Full text Link to item Cite

Adjuvant versus salvage radiation therapy for prostate cancer and the risk of death.

Journal Article BJU Int · December 2010 Featured Publication OBJECTIVE: To investigate whether salvage radiation therapy (RT) for prostate-specific antigen (PSA) failure can provide the same result as adjuvant RT, which decreases the risk of all-cause mortality (ACM) for men with positive margins (R1), or extra-caps ... Full text Link to item Cite

Prostate-specific antigen-based risk-adapted discontinuation of prostate cancer screening in elderly African American and Caucasian American men.

Journal Article Urology · November 2010 Featured Publication OBJECTIVES: To evaluate the relationship between initial prostate-specific antigen (PSA) and prostate cancer (PCa) risk in elderly African American (AA) and Caucasian American (CA) men. METHODS: A total of 408 AA and 1720 CA men whose initial PSA measureme ... Full text Link to item Cite

Predicting non-organ-confined prostate cancer in men diagnosed after 2000.

Journal Article Prostate Cancer Prostatic Dis · September 2010 Featured Publication The objective of this study was to preoperatively predict non-organ-confined disease in patients considering radical prostatectomy. To account for the stage migration seen in prostate cancer, we included only those patients who underwent prostatectomy afte ... Full text Link to item Cite

Predicting occult multifocality of renal cell carcinoma.

Journal Article Eur Urol · July 2010 Featured Publication BACKGROUND: Multifocal renal cell carcinoma (RCC) has been reported in up to 25% of all radical nephrectomy specimens. Modern imaging tends to underestimate the rate of multifocality. Recognition of multifocality before treatment may guide physicians and p ... Full text Link to item Cite

Public survey and survival data do not support recommendations to discontinue prostate-specific antigen screening in men at age 75.

Journal Article Urology · May 2010 Featured Publication OBJECTIVES: To evaluate the US Preventative Services Task Force (USPSTF) recommendation to discontinue prostate-specific antigen (PSA) screening at age 75. METHODS: Public survey: A cohort of 340 patients was surveyed at our PSA screening clinic and strati ... Full text Link to item Cite

Impact of postoperative prostate-specific antigen disease recurrence and the use of salvage therapy on the risk of death.

Journal Article Cancer · April 15, 2010 Featured Publication BACKGROUND: This report evaluated whether biochemical recurrence (BCR) as a time-dependent covariate (t) after radical prostatectomy (RP) for prostate cancer was associated with the risk of death and whether salvage therapy with radiotherapy (RT) and/or ho ... Full text Link to item Cite

Initial prostate specific antigen 1.5 ng/ml or greater in men 50 years old or younger predicts higher prostate cancer risk.

Journal Article J Urol · March 2010 Featured Publication PURPOSE: Studies show that initial prostate specific antigen higher than the median in young men predicts a subsequent higher risk of prostate cancer. To our knowledge this relationship has not been studied in patients stratified by race. MATERIALS AND MET ... Full text Link to item Cite

Tumor percent involvement predicts prostate specific antigen recurrence after radical prostatectomy only in men with smaller prostate.

Journal Article J Urol · March 2010 Featured Publication PURPOSE: We determined the predictive power of tumor percent involvement on prostate specific antigen recurrence in patients when stratified by prostate weight. MATERIALS AND METHODS: Data on 3,057 patients who underwent radical prostatectomy between 1988 ... Full text Link to item Cite

Tumor volume, tumor percentage involvement, or prostate volume: which is predictive of prostate-specific antigen recurrence?

Journal Article Urology · February 2010 Featured Publication OBJECTIVES: To compare the effects of tumor volume (TV), tumor percentage involvement (TPI), and prostate volume (PV) on prostate-specific antigen (PSA) recurrence (PSAR) after radical prostatectomy (RP). METHODS: A cohort of 3528 patients receiving RP bet ... Full text Link to item Cite

Men older than 70 years have higher risk prostate cancer and poorer survival in the early and late prostate specific antigen eras.

Journal Article J Urol · November 2009 Featured Publication PURPOSE: We clarified whether men older than 70 years have a higher risk of prostate cancer and poorer survival in the early and late prostate specific antigen eras. MATERIALS AND METHODS: A cohort of 4,561 men who underwent radical prostatectomy were stra ... Full text Link to item Cite

High-intensity focused ultrasound for prostate cancer: comparative definitions of biochemical failure.

Journal Article BJU Int · October 2009 Featured Publication OBJECTIVES: To compare the specificity and sensitivity of different definitions of biochemical failure in patients treated with high-intensity focused ultrasound (HIFU) for prostate cancer, to identify the most accurate predictor of clinical failure after ... Full text Link to item Cite

Prostate-specific antigen screening and prostate cancer mortality: Implications of a randomized European study

Journal Article Aging Health · September 18, 2009 Over the past two decades, prostate-specific antigen has become the primary modality for prostate cancer screening and has led to earlier detection. However, the question remains as to whether earlier detection actually leads to reductions in prostate canc ... Full text Cite

Delayed prostate-specific antigen recurrence after radical prostatectomy: how to identify and what are their clinical outcomes?

Journal Article Urology · September 2009 Featured Publication OBJECTIVES: To identify factors that predict delayed (> 5 years) prostate-specific antigen recurrence (PSAR) after radical prostatectomy (RP) and to analyze the associated clinical outcomes. METHODS: A cohort of 4561 men who underwent RP between 1988 and 2 ... Full text Link to item Cite

Effect of age and pathologic Gleason score on PSA recurrence: analysis of 2911 patients undergoing radical prostatectomy.

Journal Article Urology · September 2009 Featured Publication OBJECTIVES: To clarify the relationship between age and pathologic Gleason score and their effect on prostate-specific antigen recurrence (PSAR). METHODS: The data from a cohort of 2911 men who had undergone radical prostatectomy from 1988 to 2006 were ret ... Full text Link to item Cite

A retrospective comparison of anesthetic management of robot-assisted laparoscopic radical prostatectomy versus radical retropubic prostatectomy.

Journal Article J Clin Anesth · August 2009 Featured Publication STUDY OBJECTIVE: To compare anesthetic management and postoperative outcomes in patients undergoing robot-assisted laparoscopic radical prostatectomy (RALP) and radical retropubic prostatectomy (RRP) with general anesthesia. DESIGN: Retrospective database ... Full text Link to item Cite

Factors predicting prostatic biopsy Gleason sum under grading.

Journal Article J Urol · July 2009 Featured Publication PURPOSE: We determined clinical factors affecting the under grading of biopsy Gleason sum compared with prostatectomy pathology and developed a model predicting the probability of under grading. MATERIALS AND METHODS: We analyzed a cohort of 1,701 patients ... Full text Link to item Cite

PREDICTING NON-ORGAN CONFINED PROSTATE CANCER AFTER THE YEAR 2000

Journal Article The Journal of Urology · April 2009 Full text Cite

PERINEAL RADICAL PROSTATECTOMY: WHAT ARE THE TEN YEAR OUTCOMES?

Journal Article Journal of Urology · April 2009 Full text Cite

Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery.

Journal Article Cancer Epidemiol Biomarkers Prev · December 2008 Featured Publication BACKGROUND: Prostate cancer affects one of six men during their lifetime. Dietary factors are postulated to influence the development and progression of prostate cancer. Low-fat diets and flaxseed supplementation may offer potentially protective strategies ... Full text Link to item Cite

Significant discrepancies between diagnostic and pathologic Gleason sums in prostate cancer: the predictive role of age and prostate-specific antigen.

Journal Article Urology · October 2008 Featured Publication OBJECTIVES: To assess the discrepancies between diagnostic and pathologic Gleason sums and the predictive role of age and prostate-specific antigen (PSA) level on Gleason sum discrepancies. METHODS: A total of 2963 patients receiving radical prostatectomy ... Full text Link to item Cite

Body mass index, prostate-specific antigen, and digital rectal examination findings among participants in a prostate cancer screening clinic.

Journal Article Urology · May 2008 Featured Publication OBJECTIVES: Prior studies suggested obese men have lower prostate-specific antigen (PSA) values. However, the association between body mass index (BMI) and digital rectal examination (DRE) findings and the association between weight at age 18 and adult PSA ... Full text Link to item Cite

Race and prostate weight as independent predictors for biochemical recurrence after radical prostatectomy.

Journal Article Prostate Cancer Prostatic Dis · 2008 Featured Publication We hypothesized that factors beyond pathological stage, grade, PSA and margin status would be important predictors of biochemical recurrence (BCR) after radical prostatectomy (RP). A cohort of 3194 patients who underwent RP between 1988 and 2007 and who ha ... Full text Link to item Cite

Rectourethral fistula after combination radiotherapy for prostate cancer.

Journal Article Urology · May 2007 Featured Publication OBJECTIVES: To describe 6 cases of rectourethral fistula in patients treated with brachytherapy plus external beam radiotherapy for localized prostate cancer and subsequent rectal biopsies or rectal surgery. METHODS: A retrospective chart review was undert ... Full text Link to item Cite

The role of early adopter bias for new technologies in robot assisted laparoscopic prostatectomy.

Journal Article J Urol · April 2007 Featured Publication PURPOSE: We determined the potential influence of an early adopter bias in patients undergoing robot assisted laparoscopic prostatectomy. MATERIALS AND METHODS: We compared baseline demographic, clinical and health related quality of life characteristics o ... Full text Link to item Cite

Prostate-specific antigen (PSA) and PSA velocity for prostate cancer detection in men aged <50 years.

Journal Article BJU Int · April 2007 Featured Publication OBJECTIVE: To identify threshold values of prostate-specific antigen (PSA) levels and PSA velocity (PSAV) to optimize the assessment of the risk of prostate cancer in young men, as prostate cancer is detected increasingly in men aged <50 years. PATIENTS AN ... Full text Link to item Cite

Comparative financial analysis of minimally invasive surgery to open surgery for small renal tumours < or =3.5 cm: a single institutional experience.

Journal Article Eur Urol · March 2007 Featured Publication OBJECTIVE: We analysed total hospital costs by comparing minimally invasive surgery (MIS) procedures, such as laparoscopic cryoablation (LCA), laparoscopic partial nephrectomy (LPN), and hand-assisted laparoscopic nephrectomy (HALN), with conventional surg ... Full text Link to item Cite

Financial comparative analysis of minimally invasive surgery to open surgery for localized prostate cancer: a single-institution experience.

Journal Article Urology · February 2007 Featured Publication OBJECTIVES: To evaluate the financial implications of how the costs of new minimally invasive surgery such as laparoscopic robotic prostatectomy (LRP) and cryosurgical ablation of the prostate (CAP) technologies compare with those of conventional surgery. ... Full text Link to item Cite

Age adjusted prostate specific antigen and prostate specific antigen velocity cut points in prostate cancer screening.

Journal Article J Urol · February 2007 Featured Publication PURPOSE: We identified age adjusted prostate specific antigen and prostate specific antigen velocity cut points for prostate cancer biopsy. MATERIALS AND METHODS: A cohort of 33,643 men was retrieved from the Duke Prostate Center database. Of this group 11 ... Full text Link to item Cite

Testicular cancer. Clinical practice guidelines in oncology.

Journal Article J Natl Compr Canc Netw · November 2006 Featured Publication Full text Link to item Cite

Kidney cancer. Clinical practice guidelines in oncology.

Journal Article J Natl Compr Canc Netw · November 2006 Featured Publication Full text Link to item Cite

Timing and patterns of recurrences and deaths from prostate cancer following adjuvant pelvic radiotherapy for pathologic stage T3/4 adenocarcinoma of the prostate.

Journal Article Prostate Cancer Prostatic Dis · 2006 Featured Publication To determine the timing and patterns of late recurrence after radical prostatectomy (RP) alone or RP plus adjuvant radiotherapy (RT). Between 1970 and 1983, 159 patients underwent RP for newly diagnosed adenocarcinoma of the prostate and were found to have ... Full text Link to item Cite

Complications after percutaneous radiofrequency ablation of renal tumors.

Journal Article Urology · December 2005 OBJECTIVES: To evaluate our experience with percutaneous radiofrequency ablation (pRFA) to determine common characteristics of patients with complications, to elucidate possible relative contraindications to therapy. METHODS: Medical records of all patient ... Full text Link to item Cite

Supplement use among men with prostate cancer.

Journal Article Urology · July 2005 OBJECTIVES: To characterize supplement use within a sample population of men diagnosed with prostate cancer. METHODS: A census of men diagnosed with prostate cancer at Duke University Medical Center from 1997 to 2002 (n = 1402) was mailed a survey that asc ... Full text Link to item Cite

Kidney cancer. Clinical practice guidelines.

Journal Article J Natl Compr Canc Netw · January 2005 Featured Publication Link to item Cite

Testicular cancer. Clinical practice guidelines.

Journal Article J Natl Compr Canc Netw · January 2005 Featured Publication Link to item Cite

Pilot study to explore effects of low-fat, flaxseed-supplemented diet on proliferation of benign prostatic epithelium and prostate-specific antigen.

Journal Article Urology · May 2004 OBJECTIVES: Dietary factors may influence the prostate and have an impact on prostatic growth and disease. A small number of studies have suggested that flaxseed-supplemented, fat-restricted diets may thwart prostate cancer growth in both animals and human ... Full text Link to item Cite

Moderators of an uncertainty management intervention: for men with localized prostate cancer.

Journal Article Nurs Res · 2003 BACKGROUND: The effectiveness of psycho-educational interventions for cancer patients is well documented, but less is known about moderating characteristics that determine which subgroups of patients are most likely to benefit. OBJECTIVES: The aim of this ... Full text Link to item Cite

Comparison of [18 F]fluorocholine and [18 F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer.

Journal Article J Urol · July 2002 Featured Publication PURPOSE: Positron emission tomography (PET) imaging is used for the metabolic evaluation of cancer. [18F]fluorodeoxyglucose (FDG) is commonly used as a radiotracer but its low cellular uptake rate in prostate cancer limits its usefulness. We evaluated the ... Link to item Cite

Helping patients with localized prostate carcinoma manage uncertainty and treatment side effects: nurse-delivered psychoeducational intervention over the telephone.

Journal Article Cancer · March 15, 2002 BACKGROUND: The objective of this study was to test the efficacy of an individualized uncertainty management intervention delivered by telephone to Caucasian and African-American men with localized prostate carcinoma and directed at managing the uncertaint ... Full text Link to item Cite

Pilot study of dietary fat restriction and flaxseed supplementation in men with prostate cancer before surgery: exploring the effects on hormonal levels, prostate-specific antigen, and histopathologic features.

Journal Article Urology · July 2001 Featured Publication OBJECTIVES: Dietary fat and fiber affect hormonal levels and may influence cancer progression. Flaxseed is a rich source of lignan and omega-3 fatty acids and may thwart prostate cancer. The potential effects of flaxseed may be enhanced with concomitant fa ... Full text Link to item Cite

Heat shock protein 70 (HSP70) does not prevent the inhibition of cell growth in DU-145 cells treated with TGF-beta1.

Journal Article Anticancer Res · 2001 Featured Publication BACKGROUND: Mitogen-activated protein kinase (MAPK) is one of the transforming growth factor-beta (TGF-beta signaling pathways while heat shock protein 70 (HSP70) prevents apoptosis by affecting MAPK signaling downstream. However, the interrelationship bet ... Link to item Cite

Synthesis and evaluation of 18F-labeled choline as an oncologic tracer for positron emission tomography: initial findings in prostate cancer.

Journal Article Cancer Res · January 1, 2001 Featured Publication The up-regulation of rates of choline uptake and phosphorylation in certain malignancies has motivated the development of positron-labeled choline analogues for noninvasive detection of cancer using positron emission tomography (PET). The choline analogue, ... Link to item Cite

Early onset baldness and prostate cancer risk.

Journal Article Cancer Epidemiol Biomarkers Prev · March 2000 Featured Publication Prostatic carcinoma is the leading cancer among American men, yet few risk factors have been established. Although increased androgen levels have long been associated with both prostatic carcinoma and baldness, to date no studies have shown an association ... Link to item Cite

Transient lumbosacral polyradiculopathy after prostatectomy: association with spinal stenosis.

Journal Article South Med J · August 1999 Featured Publication Mononeuropathies are common after pelvic surgery. They are usually the result of unnatural positioning during surgery or faulty restraining devices. Polyneuropathy in the postoperative setting is rare. We report two cases of polyradiculopathy after radical ... Full text Link to item Cite

QOL and outcomes research in prostate cancer patients with low socioeconomic status.

Journal Article Oncology (Williston Park) · June 1999 Featured Publication The VA Cancer of the Prostate Outcomes Study (VA CaPOS) is collecting quality-of-life (QOL) information from prostate cancer patients, spouses, and physicians at six VA medical centers. Currently, 601 men with prostate cancer are included in the study, mos ... Link to item Cite

Molecular cytogenetic analysis of the bladder carcinoma cell line BK-10 by spectral karyotyping.

Journal Article Genes Chromosomes Cancer · May 1999 Featured Publication The bladder cancer cell line BK-10 was established from a grade III-IV transitional cell carcinoma (TCC). BK-10 is near-tetraploid (+/-4n) and consists of two subclones with 20-25 structural aberrations. Here we report the cytogenetic analysis of BK-10 by ... Full text Link to item Cite

Hextend, a physiologically balanced plasma expander for large volume use in major surgery: a randomized phase III clinical trial. Hextend Study Group.

Journal Article Anesth Analg · May 1999 UNLABELLED: Hextend (BioTime, Inc., Berkeley, CA) is a new plasma volume expander containing 6% hetastarch, balanced electrolytes, a lactate buffer, and physiological levels of glucose. In preclinical studies, its use in shock models was associated with an ... Full text Link to item Cite

The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction.

Journal Article Cancer Res · August 15, 1998 Arylamines are known bladder carcinogens and are an important constituent of tobacco smoke. The handling of arylamines in the body is complex and includes metabolism by NAT1 and NAT2, enzymes that play a role in both activation and detoxification of arylam ... Link to item Cite

Peptidyl membrane-interactive molecules are cytotoxic to prostatic cancer cells in vitro.

Journal Article World J Urol · 1998 Cytotoxic membrane disruption via lytic peptides is a well-recognized mechanism of immune surveillance for antifungal and antibacterial host protection. Naturally occurring lytic peptides were shown to exhibit antitumor activity as well. Peptidyl membrane- ... Full text Link to item Cite

Isolation and characterization of a novel human bladder cancer cell line: BK10.

Journal Article In Vitro Cell Dev Biol Anim · 1998 Molecular studies of bladder carcinomas have aided in determining causative genetic events and the prognosis of cancers endowed with certain abnormalities. In vitro bladder cancer characterization of key cytogenetic alterations is useful for study of molec ... Full text Link to item Cite

Does prostate transitional cell carcinoma preclude orthotopic bladder reconstruction after radical cystoprostatectomy for bladder cancer?

Journal Article J Urol · December 1997 PURPOSE: We determined if urethral preservation and orthotopic bladder replacement in patients with transitional cell carcinoma within the prostatic urethra or prostate placed these patients at risk for urethral recurrence or death. MATERIALS AND METHODS: ... Full text Link to item Cite

Selection criteria for urethral preservation

Other British Journal of Urology · December 1, 1997 The traditional indications for urethrectomy are multifocal disease within the bladder, diffuse intravesical carcinoma-in-situ, malignancy at the bladder neck or any prostatic transitional malignancy. Previous review of our experience showed no significant ... Cite

Early management of acute severe asthma.

Journal Article Lancet · April 5, 1997 Full text Link to item Cite

Anthropometric risk factors for prostate cancer.

Journal Article Nutr Cancer · 1997 Cancer of the prostate is the leading cancer among American men, yet few risk factors are known. Anthropometry may help uncover potential risk factors for prostate cancer, since fat distribution, skeletal structure, and musculature may differ between men w ... Full text Link to item Cite

Fenretinide: induction of apoptosis and endogenous transforming growth factor beta in PC-3 prostate cancer cells.

Journal Article Cell Growth Differ · January 1997 N-(4-Hydroxyphenyl)retinamide (4-HPR, Fenretinide) is a retinoid derivative with antineoplastic activity in various tumor types including prostate carcinoma. The mechanism of action of 4-HPR toxicity is unknown. 4-HPR induces apoptosis in leukemia- and lym ... Link to item Cite

Endoscopic brush cytology of the upper urinary tract. Evaluation of its efficacy and potential limitations in diagnosis.

Journal Article Acta Cytol · 1997 OBJECTIVE: To evaluate the efficacy of endoscopic brush cytology in diagnosing transitional cell carcinoma of the upper urinary tract. STUDY DESIGN: Sixty-three endoscopic brush cytology specimens from 48 patients were compared with corresponding cytologic ... Full text Link to item Cite

Serum androgens: associations with prostate cancer risk and hair patterning.

Journal Article J Androl · 1997 Cancer of the prostate is the leading cancer among American men, yet few risk factors have been established. Hair growth and development are influenced by androgens, and it has long been suspected that prostate cancer also is responsive to these hormones. ... Link to item Cite

Correlation of DNA ploidy and histologic diagnosis from prostate core-needle biopsies: is DNA ploidy more sensitive than histology for the diagnosis of carcinoma in small specimens?

Journal Article J Surg Oncol · September 1996 DNA ploidy has been shown to have prognostic value in adenocarcinoma of the prostate. While occasional benign lesions of the prostate may be associated with a DNA aneuploid status, most aneuploid epithelial proliferations of the prostate are carcinomas. Be ... Full text Link to item Cite

Induction of apoptosis by diethylstilbestrol in hormone-insensitive prostate cancer cells.

Journal Article J Natl Cancer Inst · July 3, 1996 BACKGROUND: Diethylstillbestrol (DES) and diethylstilbestrol diphosphate (DESdP) are effective agents for the treatment of advanced prostate cancers. Tumor-inhibiting effects of DES and DESdP are presumed secondary to suppression of androgen production in ... Full text Link to item Cite

Glutathione and glutathione S-transferase in benign and malignant prostate cell lines and prostate tissues.

Journal Article Biochem Pharmacol · January 12, 1996 Metastatic prostate adenocarcinoma is unresponsive to alkylator chemotherapy with virtually no prolonged remissions. Glutathione (GSH) and glutathione S-transferase (GST) have been reported to play a role in tumor resistance to alkylator therapy; however, ... Full text Link to item Cite

Isolation and characterization of a novel human prostatic stromal cell culture: DuK50.

Journal Article In Vitro Cell Dev Biol Anim · December 1995 A novel human prostatic stromal cell culture, designated DuK50, has been passed in vitro > 12 mo. Tissue cultures were obtained from material harvested within a normal region of a radical prostatectomy specimen. These monolayers exhibited normal fibroblast ... Full text Link to item Cite

Knowledge, beliefs, and prior screening behavior among blacks and whites reporting for prostate cancer screening.

Journal Article Urology · September 1995 OBJECTIVES: A survey to determine prostate cancer-related knowledge, beliefs, and prior screening behavior was administered to men participating in prostate cancer screening events at nine major sites in the southeast. Since prostate cancer disproportionat ... Full text Link to item Cite

Adjuvant radiotherapy for pathologic stage T3/4 adenocarcinoma of the prostate: ten-year update.

Journal Article Int J Radiat Oncol Biol Phys · August 30, 1995 PURPOSE: To determine the role of adjuvant postoperative radiotherapy (RT) following radical prostatectomy (RP) in a group of patients with pathologic Stage T3/4 adenocarcinoma of the prostate followed for a median of 10 years after treatment. METHODS AND ... Full text Link to item Cite

The alpha 1C-adrenoceptor in human prostate: cloning, functional expression, and localization to specific prostatic cell types.

Journal Article Br J Pharmacol · August 1995 1. Benign prostatic hyperplasia (BPH) causes urinary obstruction in aging men that frequently requires surgery to relieve the symptoms of urinary retention, nocturia, and micturition. Smooth muscle tone which contributes to the urethral constriction in the ... Full text Link to item Cite

Efficient gene transfer with adeno-associated virus-based plasmids complexed to cationic liposomes for gene therapy of human prostate cancer.

Journal Article Cancer Res · June 1, 1995 We have shown previously that treatment of rats bearing the Dunning R3327 MatLyLu prostatic tumor with human interleukin 2 (IL-2) gene-modified tumor cell preparations induces potent antitumor immunity in the animal. To test the clinical feasibility of usi ... Link to item Cite

6-Methylene progesterone is cytotoxic to human cancer cell lines independent of its 5-alpha-reductase activity.

Journal Article Prostate · January 1995 This investigation examined the effects of 6-methylene progesterone (6MP), an irreversible inhibitor of 5-alpha-reductase, on prostatic cancer (PC) cell lines. Dose titration microculture tetrazolium assays were used to evaluate cytotoxicity in cultures tr ... Full text Link to item Cite

Differential immunoreactivity of transforming growth factor alpha in benign, dysplastic and malignant prostatic tissues.

Journal Article Surg Oncol · August 1994 Immunohistochemical examination of radical prostatectomy specimens from 57 patients was performed to determine the differential expression of transforming growth factor alpha in the human prostate. In addition, epidermal growth factor receptor (EGFr) immun ... Full text Link to item Cite

Characteristics of men reporting for prostate cancer screening.

Journal Article Urology · September 1993 A survey to determine demographics, prostate cancer screening practices, and prostate cancer-related knowledge and beliefs was administered to over 1,700 participants at five sites during Prostate Cancer Awareness Week (1991) screening events. Findings are ... Full text Link to item Cite

Flow cytometric DNA analysis of interleukin-2 responsive renal cell carcinoma.

Journal Article J Surg Oncol · August 1993 Adoptive immunotherapy using interleukin-2 (IL-2) based therapy can result in marked tumor regression in some patients with metastatic renal cell carcinoma. DNA flow cytometry has not been previously studied as a predictor of outcome of this therapy. Archi ... Full text Link to item Cite

Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer.

Journal Article J Natl Cancer Inst · July 21, 1993 BACKGROUND: Numerous studies have associated bladder cancer with exposure to carcinogens present in tobacco smoke and other environmental or occupational exposures. Approximately 50% of all humans inherit two deleted copies of the GSTM1 gene which encodes ... Full text Link to item Cite

Differential immunoreactivity of epidermal growth factor receptor in benign, dysplastic and malignant prostatic tissues.

Journal Article J Urol · January 1993 To investigate epidermal growth factor receptor (EGFr) presence in the prostate, monoclonal antibody (clone EGFR1) immunohistochemical examination of radical prostatectomy specimens was performed (n = 37). All prostatic specimens contained benign prostatic ... Full text Link to item Cite

Glutathione depletion increases the cytotoxicity of melphalan to PC-3, an androgen-insensitive prostate cancer cell line.

Journal Article Cancer Chemother Pharmacol · 1993 Prostate cancer that is androgen-insensitive is unresponsive to a wide spectrum of cytotoxic agents, including all of the alkylating agents. Since a major pathway for the detoxification of the alkylating agents is conjugation with glutathione (GSH), GSH de ... Full text Link to item Cite

Detection of human papillomavirus in the prostate by polymerase chain reaction and in situ hybridization.

Journal Article J Urol · December 1992 Human papillomavirus is associated with a variety of anogenital lesions, including genital warts, precancers and cancers. In male patients human papillomavirus has been identified in proliferative lesions ranging from penile and urethral warts to penile an ... Full text Link to item Cite

Prostate cancer in North Carolina.

Journal Article N C Med J · September 1992 Link to item Cite

Differential immunoreactivity of her-2/neu oncoprotein in prostatic tissues.

Journal Article Surg Oncol · April 1992 To investigate HER-2/neu oncoprotein immunoreactivity, monoclonal antibody TA1 immunohistochemical examination of flash-frozen radical prostatectomy specimens was performed (n = 35). All prostatic specimens contained benign prostatic hyperplasia (BPH) and/ ... Full text Link to item Cite

Positive margins: is adjunctive radiation therapy indicated?

Journal Article Acta Oncol · 1991 Patients with margin positive disease after radical prostatectomy are prognostically disadvantaged. The question of postoperative adjunctive radiotherapy in these patients is controversial. A retrospective study suggested that adjunctive radiation therapy ... Full text Link to item Cite

DNA in radical prostatectomy specimens. Prognostic value of tumor ploidy.

Journal Article Acta Oncol · 1991 In a series of 94 patients with prostatic adenocarcinoma the prognostic significance of some factors was studied after radical prostatectomy. DNA ploidy was assessed by flow cytometry of cells from deparaffinized specimens. Gleason sum, seminal vesicle sta ... Full text Link to item Cite

Radical surgery versus radiation therapy in early prostatic carcinoma.

Journal Article Acta Oncol · 1991 Patients with organ-confined prostatic cancer, as determined by digital examination, bone scans and serum acid phosphatase determination, were randomized to radical prostatectomy or external-beam radiation therapy. With respect to first evidence of treatme ... Full text Link to item Cite

The relevance of stage A malignancy in prostatic cancer.

Journal Article Acta Oncol · 1991 Patients with T1 (stage A) prostatic cancer detected on transurethral resection and patients with T2 (stage B) cancer, identified by palpation and needle biopsy, had similar time to failure and survival following radical prostatectomy. Transurethral resect ... Full text Link to item Cite

Surgical management of pheochromocytoma with the use of metyrosine.

Journal Article Ann Surg · November 1990 Despite recommended preoperative preparation with alpha-adrenergic blockers, severe hemodynamic instability may occur during operations to resect pheochromocytoma. We combined the alpha-blocker phenoxybenzamine with the tyrosine hydroxylase inhibitor metyr ... Full text Link to item Cite

Preparative cytoreductive surgery in patients with metastatic renal cell carcinoma treated with adoptive immunotherapy with interleukin-2 or interleukin-2 plus lymphokine activated killer cells.

Journal Article J Urol · September 1990 A total of 63 patients with metastatic renal cell carcinoma with the primary kidney tumor in place was accepted as candidates for immunotherapy at the Surgery Branch of the National Cancer Institute. Of the 63 patients 54 underwent nephrectomy and 9 were t ... Full text Link to item Cite

Collecting duct carcinoma of the kidney.

Journal Article Hum Pathol · April 1990 Collecting duct carcinoma is an unusual variant of renal cell carcinoma, whose appearance and behavior are not well established. We identified six cases of collecting duct carcinoma in our files. The clinical, pathologic, and immunohistochemical characteri ... Full text Link to item Cite

Epidermal growth factor receptor gene analysis in renal cell carcinoma.

Journal Article J Urol · January 1990 The epidermal growth factor receptor binds the mitogens epidermal growth factor and transforming growth factor-alpha. Increased expression of the epidermal growth factor receptor has been noted in many types of tumors and is associated with gene amplificat ... Full text Link to item Cite

Biotherapy and chemotherapy of renal cell carcinoma

Journal Article Problems in Urology · January 1, 1990 Renal cell carcinoma is a universally fatal condition when metastatic. Rare spontaneous regressions are noted occasionally, as well as prolonged disease-free intervals between therapies. Surgical therapy is possibly adjunctive to effective systemic therapi ... Cite

Clinically occult Leydig cell tumor presenting with gynecomastia.

Journal Article J Urol · November 1989 An occult Leydig cell tumor is described in a patient who presented with gynecomastia. Diagnosis was established by means of testicular ultrasonography and selective testicular venous sampling. The pathophysiology and management of this rare disease entity ... Full text Link to item Cite

The detection of renal carcinoma extension into the renal vein and inferior vena cava: a prospective comparison of venacavography and magnetic resonance imaging.

Journal Article J Urol · October 1989 Accurate preoperative evaluation of the inferior vena cava and renal vein in patients with renal cell carcinoma is mandatory to plan a successful surgical approach. The presence of venous extension may alter transfusion and anesthetic requirements, as well ... Full text Link to item Cite

Genetic changes in human adrenocortical carcinomas.

Journal Article J Natl Cancer Inst · April 5, 1989 Recent studies have suggested that loss of heterozygosity at loci on the short arm of human chromosome 11 (11p) may be important in the pathogenesis of benign and malignant adrenal cortical tumors. To test this concept, adrenocortical carcinomas from nine ... Full text Link to item Cite

The inhibition of human adrenal steroidogenic enzyme activities by suramin.

Journal Article J Clin Endocrinol Metab · February 1989 Suramin has recently been used to treat patients with acquired immune deficiency syndrome because of the action of this drug on reverse transcriptase. Patients so treated developed the symptoms and hormonal profiles of adrenal insufficiency. To evaluate th ... Full text Link to item Cite

Fournier gangrene: diagnosis with scrotal US.

Journal Article Radiology · November 1988 Skin thickening and subcutaneous air were detected at ultrasound (US) of the scrotum in a patient with normal-appearing testicles and signs and symptoms suggestive of an acute inflammatory process, such as epidydimitis or orchitis. The patient was found to ... Full text Link to item Cite

Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study.

Journal Article J Clin Oncol · May 1988 Clinical investigations using the adoptive transfer of lymphokine-activated killer (LAK) cells and recombinant interleukin-2 (rIL-2) to treat patients with advanced cancer have yielded encouraging results. We have thus sought ways to enhance the effectiven ... Full text Link to item Cite

Late hematogenous infection of penile prostheses.

Journal Article J Urol · January 1988 Late deep wound infection caused by hematogenous bacterial spread from a remote focus is a rare but disastrous complication of prosthetic devices. Six patients with probable late hematogenous infection are described. The initial implantation was free of co ... Full text Link to item Cite

A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone.

Journal Article N Engl J Med · April 9, 1987 We studied the effects of adoptive immunotherapy with lymphokine-activated killer (LAK) cells plus interleukin-2 or therapy with high-dose interleukin-2 alone in 157 patients with metastatic cancer for whom standard therapy had proved ineffective or no sta ... Full text Link to item Cite

Bladder substitution in children.

Journal Article Urol Clin North Am · May 1986 In spite of all the difficulties, cystoplasty, particularly with the ileocecal segment, has proved rewarding. Undiversion is easily accomplished in this way. Most patients are outwardly well and happy. Reflux usually does no harm in the near term, especial ... Link to item Cite

Use of the rectus abdominis muscle flap in urological reconstructive procedures.

Journal Article J Urol · May 1986 The rectus abdominis muscle flap has been used successfully in 4 reconstructive procedures complicated by tissue loss or urinary fistula. This simple procedure is advocated as an alternative to the use of omentum when prior abdominal surgery precludes omen ... Full text Link to item Cite

Human recombinant TNF-mediates bone resorption in vitro

Journal Article Surgical Forum · January 1, 1986 Cite

A new technique for the prevention of reflux in those undergoing bladder substitution or undiversion using bowel segments

Journal Article World Journal of Urology · December 1, 1985 The use of small and large bowel segments in reconstruction of the bladder and in continent urinary diversion has become increasingly practical in recent years. Many of these patients are expected to achieve a near normal life and life expectancy as a resu ... Full text Cite

Lethal complications of standard self-retaining ureteral stents in patients with ileal conduit urinary diversion.

Journal Article J Urol · May 1985 While standard commercially available pigtail ureteral stents are used commonly in the obstructed patient, particularly when metastatic disease has been identified, our recent experience suggests caution in the use of such stents for patients with ileal co ... Full text Link to item Cite

The vascularized skin island urethroplasty: its role and results in urethral stricture management.

Journal Article J Urol · January 1985 We report 11 vascularized island skin flap urethroplasties. Results appear to be excellent when the procedure is used for strictures of the pendulous urethra. Use of vascularized skin flap urethroplasties for the repair of bulbar and membranous strictures ... Full text Link to item Cite