Conventional Ultrafiltration During Elective Cardiac Surgery and Postoperative Acute Kidney Injury.
OBJECTIVE: Conventional ultrafiltration (CUF) during cardiopulmonary bypass (CPB) serves to hemoconcentrate blood volume to avoid allogeneic blood transfusions. Previous studies have determined CUF volumes as a continuous variable are associated with postoperative acute kidney injury (AKI) after cardiac surgery, but optimal weight-indexed volumes that predict AKI have not been described. DESIGN: Retrospective cohort. SETTING: Single-center university hospital. PARTICIPANTS: A total of 1,641 consecutive patients who underwent elective cardiac surgery between June 2013 and December 2015. INTERVENTIONS: The CUF volume was removed during CPB in all participants as part of routine practice. The authors investigated the association of dichotomized weight-indexed CUF volume removal with postoperative AKI development to provide pragmatic guidance for clinical practice at the authors' institution. MEASUREMENTS AND MAIN RESULTS: Primary outcomes of postoperative AKI were defined by the Kidney Disease: Improving Global Outcomes staging criteria and dichotomized, weight-indexed CUF volumes (mL/kg) were defined by (1) extreme quartiles (
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- Ultrafiltration
- Risk Factors
- Retrospective Studies
- Prospective Studies
- Postoperative Complications
- Humans
- Cardiopulmonary Bypass
- Cardiac Surgical Procedures
- Anesthesiology
- Acute Kidney Injury
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Ultrafiltration
- Risk Factors
- Retrospective Studies
- Prospective Studies
- Postoperative Complications
- Humans
- Cardiopulmonary Bypass
- Cardiac Surgical Procedures
- Anesthesiology
- Acute Kidney Injury