Scholars@Duke
Dilraj Singh Grewal

Dilraj Singh Grewal

Professor of Ophthalmology
Ophthalmology, Vitreoretinal Diseases & Surgery

Selected Publications

Choroidal vascularity index as a marker of health and disease: systematic review and meta-analyses.

Journal Article Surv Ophthalmol · 2026 The Choroidal Vascularity Index (CVI), derived from optical coherence tomography (OCT), has emerged as a potential biomarker for detecting vascular changes. Understanding its variability across physiological states, ocular conditions, and systemic diseases ... Full text Link to item Cite

FYB-201 Biosimilar ranibizumab (Ongavia/Ranivisio/Cimerli) Efficacy and Safety in Clinical Settings - FORCE study.

Journal Article Eye (Lond) · December 2025 PURPOSE: To understand the early experience of ranibizumab biosimilar (FYB 201) that has been approved in the United Kingdom (Ongavia, Teva Pharmaceuticals, Tel Aviv Israel), United States (Cimerli, Sandoz Inc, Princeton, NJ, USA) and Europe (Ranivisio, Bi ... Full text Link to item Cite

Biomarkers.

Journal Article Alzheimers Dement · December 2025 BACKGROUND: We assessed differences in retinal structure and microvasculature among individuals with Alzheimer's disease (AD), APOE ε4 carriers, and APOE ε4 noncarriers. METHOD: Participants underwent cognitive evaluation with Mini-Mental State Examination ... Full text Link to item Cite

Evidence and Consensus-based Imaging Guidelines in Birdshot Chorioretinopathy: Multimodal Imaging in Uveitis (MUV) Taskforce Report 8.

Journal Article Am J Ophthalmol · October 2025 PURPOSE: To develop consensus-based imaging guidelines for diagnosing and monitoring birdshot chorioretinopathy (BSCR). DESIGN: Consensus-based approach guided by literature and an expert committee using a nominal group technique (NGT). METHODS: An expert ... Full text Link to item Cite

Retinal Layer Thickness and Volume Measurements in Traumatic Brain Injury.

Journal Article J Vitreoretin Dis · September 3, 2025 Purpose: To assess retinal layer thickness and volume by optical coherence tomography (OCT) in patients with prior traumatic brain injury (TBI). Methods: Adults (≥18 years) with prior TBI were prospectively recruited. 512 × 128-mm macular cube scans were o ... Full text Link to item Cite

Considerations and surgical approach to vitreous, retinal, and chorioretinal biopsy.

Journal Article Curr Opin Ophthalmol · August 25, 2025 PURPOSE OF REVIEW: This review summarizes the literature regarding vitreous and chorioretinal biopsy, with a focus on surgical techniques and methods to optimize diagnostic yield for the collected samples. RECENT FINDINGS: Various novel options for analyzi ... Full text Link to item Cite

Cost-Effectiveness of Treatments for Diabetic Macular Edema: Simulated Bevacizumab-First Step Therapy Versus Real-World Practice.

Journal Article J Vitreoretin Dis · August 11, 2025 Purpose: To compare the incremental cost-effectiveness of a clinical trial-simulated step-therapy versus real-world treatment for diabetic macular edema (DME). Methods: A theoretical Markov model (follow-up of 2 years and lifetime of 17 years) from the 202 ... Full text Link to item Cite

Aflibercept 2 mg biosimilar (Tyalia)-real-world experience from IRAN (ATRIA study).

Journal Article Eye (Lond) · August 2025 PURPOSE: To evaluate the early real-world clinical outcomes regarding safety and efficacy after administering the aflibercept 2 mg biosimilar (Tyalia, Cinnagen, Tehran, Iran). METHODS: A retrospective, uncontrolled observational study was conducted with a ... Full text Link to item Cite

Dopaminergic Therapies May Decrease Risk of Early and Intermediate Non-exudative Age-related Macular Degeneration Progression.

Journal Article Ophthalmic Surg Lasers Imaging Retina · July 2025 BACKGROUND AND OBJECTIVE: Age-related macular degeneration (AMD) is a leading cause of vision loss, with progression to geographic atrophy (GA) posing a significant challenge. This study aimed to assess whether dopaminergic therapies (DMTs) reduce risk of ... Full text Link to item Cite

Correlating retinal and choroidal vascular parameters with volumetric MRI in Alzheimer's disease and amnestic mild cognitive impairment.

Journal Article BMC Ophthalmol · July 1, 2025 BACKGROUND: We assess the relationships between retinal and choroidal structural and microvascular parameters and brain volumetric magnetic resonance imaging (MRI) parameters in individuals with amnestic mild cognitive impairment (aMCI) and Alzheimer's dis ... Full text Link to item Cite

EVOLUTION OF AUTOIMMUNE RETINOPATHY IN STIFF PERSON SYNDROME: A CASE REPORT.

Journal Article Retin Cases Brief Rep · May 1, 2025 PURPOSE: The aim of this study was to report a case of autoimmune retinopathy as the presenting feature of stiff person syndrome and assess its evolution. METHODS: Case report. RESULTS: A 35-year-old man presented with progressive, chronic vision loss. On ... Full text Link to item Cite

Possible Association Between Dopamine Antagonists and Increased Conversion to Exudative Age-Related Macular Degeneration.

Journal Article J Vitreoretin Dis · April 2, 2025 Purpose: To investigate whether modulating dopamine signaling affects conversion to exudative age-related macular degeneration (AMD). Methods: A retrospective cohort study was performed using the Duke Epic database. Eyes from patients with a diagnosis of n ... Full text Link to item Cite

Trends in Choroidal Vascularity Index in Cognitively Normal Individuals.

Journal Article Retina · March 4, 2025 PURPOSE: To establish a normative database of choroidal vascularity index (CVI) in cognitively normal adults. METHODS: Cognitively healthy volunteers who had a Montreal Cognitive Assessment (MoCA) score of 23 or higher were included. Exclusion criteria inc ... Full text Link to item Cite

Staining and Sizing Technique for Human Amniotic Membrane Graft in Refractory Macular Holes.

Journal Article J Vitreoretin Dis · 2025 Purpose: To describe the triple S technique for aiding the visualization (staining), preparation (sizing), and placement (sliding) of human amniotic membrane grafts in cases of refractory macular holes (MHs). Methods: Brilliant blue-green dye was used to s ... Full text Link to item Cite

Clinical Outcomes of Therapeutic Interventions for Autoimmune Retinopathy: A Meta-analysis and Systematic Review.

Journal Article Ophthalmol Sci · 2025 TOPIC: Autoimmune retinopathy (AIR) is a group of rare inflammatory diseases treated with immunosuppression; however, there is no treatment consensus. This meta-analysis and review aims to investigate treatment effectiveness in slowing AIR progression. CLI ... Full text Link to item Cite

The elusive relationship between retinal anatomy and brain amyloid.

Journal Article Brain Commun · 2025 This scientific commentary refers to 'Retinal microstructure and microvasculature in association with brain amyloid burden', by Egle et al. (https://doi.org/10.1093/braincomms/fcaf013). ... Full text Link to item Cite

Bilateral Panuveitis in an Adolescent with Autoimmune Lymphoproliferative Syndrome Due to CTLA4 Haploinsufficiency.

Journal Article Ocul Immunol Inflamm · October 2024 PURPOSE: To describe a case of bilateral panuveitis in an 11-year-old girl with autoimmune lymphoproliferative syndrome (ALPS) due to CTLA4 haploinsufficiency. CASE DESCRIPTION: A 5-year-old girl developed cervical adenopathy, and autoimmune hemolytic anem ... Full text Link to item Cite

ORAL CURCUMIN TO REDUCE RISK OF PROLIFERATIVE VITREORETINOPATHY FOLLOWING RHEGMATOGENOUS RETINAL DETACHMENT REPAIR.

Journal Article Retina · October 1, 2024 PURPOSE: To evaluate outcomes of patients who underwent rhegmatogenous retinal detachment repair and were started on oral curcumin for proliferative vitreoretinopathy (PVR) prevention. METHODS: Retrospective, observational case series of eyes of patients u ... Full text Link to item Cite

Comparison of Reference and Biosimilar Medications for Pediatric Noninfectious Uveitis.

Journal Article Int Ophthalmol Clin · October 1, 2024 OBJECTIVE/PURPOSE: Compare outcomes and costs of TNF-alpha inhibitor biosimilars to reference medications in the treatment of pediatric NIU. METHODS: Patients 18 years old or below treated with reference or biosimilar TNF-alpha inhibitor for noninfectious ... Full text Link to item Cite

Filgotinib in Active Noninfectious Uveitis: The HUMBOLDT Randomized Clinical Trial.

Journal Article JAMA Ophthalmol · September 1, 2024 IMPORTANCE: Noninfectious uveitis is a leading cause of visual impairment with an unmet need for additional treatment options. OBJECTIVE: To assess the efficacy and safety of filgotinib, a Janus kinase 1 (JAK1) preferential inhibitor, for the treatment of ... Full text Link to item Cite

PENTOSAN POLYSULFATE MACULOPATHY-ASSOCIATED CYSTOID MACULAR EDEMA RESPONSIVE TO INTRAVITREAL STEROIDS.

Journal Article Retin Cases Brief Rep · September 1, 2024 PURPOSE: To report a case of angiographically silent cystoid macular edema (CME) secondary to pentosan polysulfate sodium (PPS) maculopathy responsive to intravitreal steroids. METHODS: Observational case report. RESULTS: A 52-year-old female patient with ... Full text Link to item Cite

Gaucher disease type 3c: Expanding the clinical spectrum of an ultra-rare disease.

Journal Article JIMD Rep · September 2024 Gaucher disease (GD) type 3 is an autosomal recessive lysosomal disease caused by deficiency of β-glucocerebrosidase (GCase) and encompasses a spectrum of cardiac, neurological, and ophthalmological abnormalities. Although the clinical presentations can be ... Full text Link to item Cite

Multimodal Retinal Imaging Classification for Parkinson's Disease Using a Convolutional Neural Network.

Journal Article Transl Vis Sci Technol · August 1, 2024 PURPOSE: Changes in retinal structure and microvasculature are connected to parallel changes in the brain. Two recent studies described machine learning algorithms trained on retinal images and quantitative data that identified Alzheimer's dementia and mil ... Full text Link to item Cite

Large Macular Hole: How to Manage?

Journal Article Ophthalmic Surgery Lasers and Imaging Retina · April 1, 2024 Cite

Peripapillary Optical Coherence Tomography Angiography in Alzheimer's Disease, Mild Cognitive Impairment, and Normal Cognition.

Journal Article Ophthalmic Surg Lasers Imaging Retina · February 2024 OBJECTIVE: This study aimed to identify peripapillary microvascular changes in Alzheimer's disease (AD) and mild cognitive impairment (MCI). PATIENTS AND METHODS: In this prospective study, 66 eyes of 36 subjects with AD, 119 eyes of 63 with MCI, and 513 e ... Full text Link to item Cite

Ultra-Widefield Imaging of the Retinal Macrovasculature in Parkinson Disease Versus Controls With Normal Cognition Using Alpha-Shapes Analysis.

Journal Article Transl Vis Sci Technol · January 2, 2024 PURPOSE: To investigate retinal vascular characteristics using ultra-widefield (UWF) scanning laser ophthalmoscopy in Parkinson disease (PD). METHODS: Individuals with an expert-confirmed clinical diagnosis of PD and controls with normal cognition without ... Full text Link to item Cite

Wide Field Optical Coherence Tomography and Optical Coherence Tomography Angiography in Uveitis.

Journal Article Ocul Immunol Inflamm · January 2024 BACKGROUND: We review the current literature on the use of wide-field optical coherence tomography (OCT) and wide-field optical coherence tomography angiography (OCTA) in different uveitic phenotypes as well as various sequelae of uveitis and discuss the l ... Full text Link to item Cite

Gradeability and Reproducibility of Geographic Atrophy Measurement in GATHER-1, a Phase II/III Randomized Interventional Trial.

Journal Article Ophthalmol Sci · 2024 OBJECTIVE: To validate GATHER-1 inclusion criteria and the study's primary anatomic end point by assessing the reproducibility of geographic atrophy (GA) measurements and factors that affect reproducibility. DESIGN: Post hoc analysis of phase II/III clinic ... Full text Link to item Cite

Imaging Features of Retinal Vasculitis and/or Retinal Vascular Occlusion after Brolucizumab Treatment in the Postmarketing Setting.

Journal Article Ophthalmol Sci · 2024 PURPOSE: The aim of this analysis was to characterize the spectrum of inflammatory changes arising from brolucizumab use in routine clinical practice. DESIGN: Retrospective analysis of fluorescein angiography (FA), fundus photography (FP) and OCT images ta ... Full text Link to item Cite

A Convolutional Neural Network Using Multimodal Retinal Imaging for Differentiation of Mild Cognitive Impairment from Normal Cognition.

Journal Article Ophthalmol Sci · 2024 PURPOSE: To develop a machine learning tool capable of differentiating eyes of subjects with normal cognition from those with mild cognitive impairment (MCI) using OCT and OCT angiography (OCTA). DESIGN: Evaluation of a diagnostic technology. PARTICIPANTS: ... Full text Link to item Cite

Differences in Retinal and Choroidal Microvasculature and Structure in Dementia With Lewy Bodies Compared With Normal Cognition.

Journal Article J Vitreoretin Dis · 2024 Purpose: To evaluate the retinal and choroidal microvasculature and structure in individuals with dementia with Lewy bodies (DLB) compared with controls with normal cognition using optical coherence tomography (OCT) and OCT angiography (OCTA). Methods: An ... Full text Open Access Link to item Cite

Characterizing differences in retinal and choroidal microvasculature and structure in individuals with Huntington's Disease compared to healthy controls: A cross-sectional prospective study.

Journal Article PLoS One · 2024 OBJECTIVE: To characterize retinal and choroidal microvascular and structural changes in patients who are gene positive for mutant huntingtin protein (mHtt) with symptoms of Huntington's Disease (HD). METHODS: This study is a cross-sectional comparison of ... Full text Link to item Cite

Performance of Automated Machine Learning in Predicting Outcomes of Pneumatic Retinopexy.

Journal Article Ophthalmol Sci · 2024 PURPOSE: Automated machine learning (AutoML) has emerged as a novel tool for medical professionals lacking coding experience, enabling them to develop predictive models for treatment outcomes. This study evaluated the performance of AutoML tools in develop ... Full text Link to item Cite

Analysis of the Retinal and Choroidal Vasculature Using Ultrawidefield Fundus Imaging in Mild Cognitive Impairment and Normal Cognition.

Journal Article Ophthalmol Sci · 2024 PURPOSE: To utilize ultrawidefield (UWF) imaging to evaluate retinal and choroidal vasculature and structure in individuals with mild cognitive impairment (MCI) compared with that of controls with normal cognition. DESIGN: Prospective cross sectional study ... Full text Link to item Cite

Aqueous and Plasma Levels of Phosphorylated Tau 181 in Individuals with Normal Cognition.

Journal Article J Alzheimers Dis · 2024 BACKGROUND: Plasma and cerebrospinal fluid (CSF) levels of p-tau181 have been associated with Alzheimer's disease (AD). The retina and vitreous have shown measurable quantities of phosphorylated tau 181 (p-tau181). The aqueous humor, which can be collected ... Full text Link to item Cite

Reply.

Journal Article Ophthalmol Sci · 2024 Full text Link to item Cite

Use of Color Channel Optimization in 3D Heads-Up Vitrectomy vs Standard Operating Microscope for Macular Surgeries.

Journal Article J Vitreoretin Dis · 2024 Purpose: To compare the efficacy and safety of color channel optimization with 3-dimensional (3D) heads-up vitrectomy (3D HUD group) vs standard operating microscope vitrectomy (control group) for macular surgery. Methods: This retrospective multicenter co ... Full text Link to item Cite

Longitudinal Assessment of Peripapillary Microvasculature Using Optical Coherence Tomography Angiography in Cognitively Normal Adults.

Journal Article J Vitreoretin Dis · 2024 Introduction: To evaluate longitudinal peripapillary changes in cognitively normal older adults using optical coherence tomography (OCT) and OCT angiography (OCTA). Methods: Participants older than 50 years with no history of neurodegenerative disease or c ... Full text Link to item Cite

Curbside Consultation in Retina Book Curbside Consultation in Retina: 49 Clinical Questions

Book · January 1, 2024 Curbside Consultation in Retina: 49 Clinical Questions has been updated into a Second Edition! The Second Edition contains new questions and is completely updated! Curbside Consultation in Retina: 49 Clinical Questions, Second Edition contains new question ... Full text Cite

Bevacizumab First in DRCR Protocol AC vs Real-World Physician Treatment Choice for Diabetic Macular Edema: Two-Year Cost Analysis.

Journal Article J Vitreoretin Dis · 2024 Purpose: To compare the modeled costs of the Protocol AC bevacizumab-first treatment protocol (with a switch to aflibercept for sub-responders) with real-world costs for treatment-naïve patients with diabetic macular edema (DME) over a 2-year period. Metho ... Full text Link to item Cite

Macular, Choroidal, and Peripapillary Perfusion Changes in Mild and Moderate Traumatic Brain Injury Using Optical Coherence Tomography and Angiography.

Journal Article J Vitreoretin Dis · 2024 Introduction: To compare the retinal and choroidal architecture and microvasculature between patients with mild or moderate traumatic brain injury (TBI) and controls with normal cognition using optical coherence tomography (OCT) and OCT angiography (OCTA). ... Full text Link to item Cite

Angioarchitectural alterations in the retina and choroid in frontotemporal dementia.

Journal Article PLoS One · 2024 OBJECTIVE: Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder that affects the frontal and temporal lobes of the brain, leading to cognitive decline and personality changes. The objective of this cross-sectional study was to characte ... Full text Open Access Link to item Cite

Correction: Angioarchitectural alterations in the retina and choroid in frontotemporal dementia.

Journal Article PLoS One · 2024 [This corrects the article DOI: 10.1371/journal.pone.0312118.]. ... Full text Link to item Cite

Incident glaucoma and ocular hypertension after periocular and intravitreal steroid injections: a claims-based analysis.

Journal Article BMJ Open Ophthalmol · December 22, 2023 BACKGROUND/AIMS: This study aims to determine the incidence and risk of open-angle glaucoma or ocular hypertension (OHT) following ocular steroid injections using healthcare claims data. METHODS: We retrospectively reviewed deidentified insurance claims da ... Full text Link to item Cite

Longitudinal Analysis of Retinal Microvascular and Choroidal Imaging Parameters in Parkinson's Disease Compared with Controls.

Journal Article Ophthalmol Sci · December 2023 PURPOSE: To quantify rate of change of retinal microvascular and choroidal structural parameters in subjects with Parkinson's disease (PD) compared with controls using OCT and OCT angiography (OCTA). DESIGN: Prospective longitudinal study. PARTICIPANTS: Se ... Full text Link to item Cite

VISUAL AND ANATOMICAL CHANGES AFTER DRUG CESSATION IN PENTOSAN POLYSULFATE SODIUM-ASSOCIATED MACULOPATHY.

Journal Article Retin Cases Brief Rep · September 1, 2023 PURPOSE: The purpose of this study was to describe a case of development of pentosan polysulfate sodium (PPS)-related maculopathy that exhibited potential improvement in imaging findings after drug cessation. METHODS: This study is a case report. RESULTS: ... Full text Link to item Cite

Autoimmune Inflammatory Eye Disease: Demystifying Clinical Presentations for the Internist.

Journal Article Curr Allergy Asthma Rep · August 2023 PURPOSE OF REVIEW: Provide a framework for recognizing key symptoms and clinical findings in patients with autoimmune inflammatory eye disease. RECENT FINDINGS: The most common manifestations of autoimmune inflammatory eye disease are episcleritis, sclerit ... Full text Link to item Cite

DELAYED ONSET Cutibacterium (FORMERLY Propionibacterium ) acnes ENDOPHTHALMITIS TRIGGERED BY INTRAVITREAL STEROID INJECTION.

Journal Article Retin Cases Brief Rep · July 1, 2023 PURPOSE: We report a case of delayed onset Cutibacterium acnes ( C. acnes , formerly Propionibacterium acnes or P. acnes ) endophthalmitis with the onset triggered by intravitreal steroid injection (triamcinolone acetonide) in a pseudophakic patient, 7 yea ... Full text Link to item Cite

Consensus-based recommendations for optical coherence tomography angiography reporting in uveitis.

Journal Article The British journal of ophthalmology · July 2023 Background/aimsTo establish a consensus in the nomenclature for reporting optical coherence tomography angiography (OCTA findings in uveitis.MethodsThe modified Delphi process consisted of two rounds of electronic questionnaires, followed ... Full text Cite

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries.

Journal Article Br J Surg · June 12, 2023 BACKGROUND: Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. METHODS: This study adopted a four-phase D ... Full text Link to item Cite

0.18 MG FLUOCINOLONE ACETONIDE INSERT FOR THE TREATMENT OF CHRONIC POSTOPERATIVE PSEUDOPHAKIC CYSTOID MACULAR EDEMA.

Journal Article Retina · June 1, 2023 PURPOSE: To report the outcomes of the 0.18 mg fluocinolone acetonide insert (FAi) in the treatment of chronic (>6 months) postoperative cystoid macular edema after cataract surgery. METHODS: This was a retrospective consecutive case series of eyes with ch ... Full text Link to item Cite

Intrasession Repeatability of OCT Angiography Parameters in Neurodegenerative Disease.

Journal Article Ophthalmol Sci · June 2023 PURPOSE: To assess the intrasession repeatability of macular OCT angiography (OCTA) parameters in Alzheimer's disease (AD), mild cognitive impairment (MCI), Parkinson's disease (PD), and normal cognition (NC). DESIGN: Cross sectional study. SUBJECTS: Patie ... Full text Open Access Link to item Cite

Convolutional Neural Network-Based Automated Quality Assessment of OCT and OCT Angiography Image Maps in Individuals With Neurodegenerative Disease.

Journal Article Transl Vis Sci Technol · June 1, 2023 PURPOSE: To train and test convolutional neural networks (CNNs) to automate quality assessment of optical coherence tomography (OCT) and OCT angiography (OCTA) images in patients with neurodegenerative disease. METHODS: Patients with neurodegenerative dise ... Full text Link to item Cite

Retinal Vascular Changes in Alzheimer's Dementia and Mild Cognitive Impairment: A Pilot Study Using Ultra-Widefield Imaging.

Journal Article Transl Vis Sci Technol · January 3, 2023 PURPOSE: Retinal microvascular abnormalities measured on retinal images are a potential source of prognostic biomarkers of vascular changes in the neurodegenerating brain. We assessed the presence of these abnormalities in Alzheimer's dementia and mild cog ... Full text Link to item Cite

Stepwise approach for fundus imaging in the diagnosis and management of posterior uveitis.

Journal Article Surv Ophthalmol · 2023 An array of retinochoroid imaging modalities aid in comprehensive evaluation of the immunopathological changes in the retina and choroid, forming the core component for the diagnosis and management of inflammatory disorders such as uveitis. The recent tech ... Full text Link to item Cite

Biosimilars for retinal diseases: United States-Europe awareness survey (Bio-USER - survey).

Journal Article Expert Opin Biol Ther · 2023 PURPOSE: To assess the awareness of biosimilar intravitreal anti-VEGF agents among retina specialists practicing in the United States (US) and Europe. METHODS: A 16-question online survey was created in English and distributed between Dec 01, 2021 and Jan ... Full text Link to item Cite

Rapid regression of idiopathic multifocal choroiditis with intravitreal methotrexate-wide-field optical coherence tomography angiography-based study.

Journal Article Oman J Ophthalmol · 2023 Wide-field optical coherence tomography angiography (OCTA) results in a patient of idiopathic multifocal choroiditis successfully treated with intravitreal methotrexate injections. ... Full text Link to item Cite

GLP-1 receptor agonists and diabetic retinopathy: A meta-analysis of randomized clinical trials.

Journal Article Surv Ophthalmol · 2023 Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are used to treat type 2 diabetes mellitus. Recent research suggests that GLP-1 RAs may influence diabetic retinopathy (DR). We searched ClinicalTrials.gov for trials comparing FDA-approved GLP-1 RAs to ... Full text Link to item Cite

Herpetic anterior uveitis following COVID-19 vaccines: a case series.

Journal Article Front Med (Lausanne) · 2023 PURPOSE: To report a case series of herpetic uveitis following COVID-19 vaccinations. METHODS: Demographic, clinical and treatment-related data of herpetic anterior uveitis cases was collected at five tertiary eye hospitals between January 2021 and June 20 ... Full text Link to item Cite

AN EXTRUDED SCLERAL BUCKLE

Journal Article Retina Today · October 1, 2022 Cite

Artificial intelligence in dementia.

Journal Article Curr Opin Ophthalmol · September 1, 2022 PURPOSE OF REVIEW: Artificial intelligence tools are being rapidly integrated into clinical environments and may soon be incorporated into dementia diagnostic paradigms. A comprehensive review of emerging trends will allow physicians and other healthcare p ... Full text Link to item Cite

Longitudinal Analysis of the Retina and Choroid in Cognitively Normal Individuals at Higher Genetic Risk of Alzheimer Disease.

Journal Article Ophthalmol Retina · July 2022 PURPOSE: To assess the baseline differences and longitudinal rate of change in retinal and choroidal imaging parameters between apolipoprotein ε4 (APOE ε4) carriers and noncarriers with normal cognition. DESIGN: Prospective study. SUBJECTS: Four hundred th ... Full text Link to item Cite

ASSESSMENT OF RETINAL MICROVASCULAR ALTERATIONS IN INDIVIDUALS WITH AMNESTIC AND NONAMNESTIC MILD COGNITIVE IMPAIRMENT USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Journal Article Retina · July 1, 2022 PURPOSE: To assess retinal microvascular alterations in individuals with amnestic mild cognitive impairment (MCI) and nonamnestic MCI. METHODS: One hundred twelve eyes of 59 amnestic MCI participants, 32 eyes of 17 nonamnestic MCI participants, and 111 eye ... Full text Link to item Cite

Surgical Techniques for Refractory Macular Holes.

Journal Article Int Ophthalmol Clin · July 1, 2022 Full text Link to item Cite

INTERMEDIATE UVEITIS WITH RETINAL DETACHMENT IN A PATIENT WITH POMPE DISEASE.

Journal Article Retin Cases Brief Rep · May 1, 2022 PURPOSE: To describe the ocular findings in a patient with glycogen storage disease II (Pompe disease). METHODS: Case report. RESULTS: A 14-year-old boy with Pompe disease was referred for evaluation of a retinal detachment in the left eye. Indirect ophtha ... Full text Link to item Cite

Longitudinal study of serpiginous choroiditis and serpiginous like choroiditis using wide field OCT angiography.

Journal Article Eur J Ophthalmol · May 2022 PURPOSE: To assess the ability of wide field Swept Source OCTA (SS-OCTA) imaging to detect morphological variations in Serpiginous Choroiditis (SC) and Serpiginous Like Choroiditis (SLC) in response to treatment and also analyze these findings quantitative ... Full text Link to item Cite

Challenges of personal protective equipment use among ophthalmologists during the COVID-19 pandemic: A multicenter international study.

Journal Article Eur J Ophthalmol · May 2022 PURPOSE: To explore the possible challenges and difficulties of using Personal Protective Equipment (PPE) in ophthalmic practice during the Coronavirus disease 2019 (COVID-19) pandemic. METHODS: This is a multicenter, international survey among practicing ... Full text Link to item Cite

Optical Coherence Tomography Anatomic and Temporal Biomarkers in Uveitic Macular Edema.

Journal Article Am J Ophthalmol · May 2022 PURPOSE: To assess the relationship between best-corrected visual acuity (BCVA) and optical coherence tomography (OCT) features in noninfectious uveitis (NIU)-related macular edema. DESIGN: Clinical cohort study from post hoc analysis of 2 phase 3 clinical ... Full text Link to item Cite

Artificial Intelligence and Imaging Processing in Optical Coherence Tomography and Digital Images in Uveitis.

Journal Article Ocul Immunol Inflamm · April 3, 2022 INTRODUCTION: Computer vision, understood as the area of science that trains computers to interpret digital images through both artificial intelligence (AI) and classical algorithms, has significantly advanced the analysis and interpretation of optical coh ... Full text Link to item Cite

Convolutional neural network to identify symptomatic Alzheimer's disease using multimodal retinal imaging.

Journal Article Br J Ophthalmol · March 2022 BACKGROUND/AIMS: To develop a convolutional neural network (CNN) to detect symptomatic Alzheimer's disease (AD) using a combination of multimodal retinal images and patient data. METHODS: Colour maps of ganglion cell-inner plexiform layer (GC-IPL) thicknes ... Full text Open Access Link to item Cite

Reply.

Journal Article Retina · March 1, 2022 Full text Link to item Cite

Retinal and Choroidal Changes in Men Compared with Women with Alzheimer's Disease: A Case-Control Study.

Journal Article Ophthalmol Sci · March 2022 PURPOSE: To evaluate differences in the retinal microvasculature and structure and choroidal structure among men and women with Alzheimer's disease (AD) compared with age-matched cognitively normal male and female controls. DESIGN: Case-control study of pa ... Full text Open Access Link to item Cite

Choroidal vascularity index: a step towards software as a medical device.

Journal Article Br J Ophthalmol · February 2022 The choroidal vascularity index (CVI) is a relatively new parameter, calculated off optical coherence tomography (OCT) images, for the quantitative evaluation of choroid vascularity. It is defined as the ratio of vascular area to the total choroidal area, ... Full text Link to item Cite

CLINICAL CHARACTERISTICS AND VISUAL OUTCOMES IN ENDOPHTHALMITIS AFTER KERATOPROSTHESIS IMPLANTATION.

Journal Article Retina · February 1, 2022 PURPOSE: To describe the presentation, microbiology, management, and prognosis of eyes with endophthalmitis after Boston keratoprosthesis implantation. METHODS: Retrospective case series with history, diagnostics, management, and outcomes data in endophtha ... Full text Link to item Cite

Identifying Peripapillary Radial Capillary Plexus Alterations in Parkinson's Disease Using OCT Angiography.

Journal Article Ophthalmol Retina · January 2022 PURPOSE: To compare radial peripapillary capillary (RPC) plexus vascular parameters and retinal nerve fiber layer (RNFL) thickness between those with Parkinson's disease (PD) and controls. DESIGN: Prospective, cross-sectional study. PARTICIPANTS: A total o ... Full text Link to item Cite

Choroidal imaging in uveitis: An update.

Journal Article Surv Ophthalmol · 2022 An important goal of advancements in ocular imaging algorithms and devices has been to improve the image acquisition and resolution of deeper ocular tissues, namely the choroid and its vasculature that are otherwise inaccessible to direct clinical examinat ... Full text Link to item Cite

Impact of COVID-19-related lockdown on retinal disorders treated with intravitreal injections.

Journal Article Oman J Ophthalmol · 2022 PURPOSE: To study functional changes in vision and morphological changes on optical coherence tomography (OCT) scans in patients where intravitreal therapy (IVT) with injections has been delayed due to COVID-19 pandemic lockdown. METHODS: Retrospective cro ... Full text Link to item Cite

Mycobacterium chelonae Endogenous Endophthalmitis in a Person Addicted to Intravenous Drugs Presenting as an Intraretinal Peripapillary Granuloma With Tractional Retinal Detachment.

Journal Article J Vitreoretin Dis · 2022 PURPOSE: To report a case of Mycobacterium chelonae endogenous endophthalmitis in a 28-year-old man with recent intravenous drug use that presented as an intraretinal peripapillary granuloma extending from the optic nerve head with an associated macular tr ... Full text Link to item Cite

Repeatability of Peripapillary OCT Angiography in Neurodegenerative Disease.

Journal Article Ophthalmol Sci · December 2021 PURPOSE: To assess the repeatability of peripapillary OCT angiography (OCTA) in those with Alzheimer disease (AD), mild cognitive impairment (MCI), Parkinson disease (PD), or normal cognition. DESIGN: Cross-sectional. PARTICIPANTS: Patients with a clinical ... Full text Open Access Link to item Cite

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.

Journal Article Br J Surg · September 27, 2021 BACKGROUND: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. METHODS: The primary outcome was the number needed to vaccinate (NNV) to prev ... Full text Link to item Cite

SARILUMAB FOR RECALCITRANT CYSTOID MACULAR EDEMA IN NON-PARANEOPLASTIC AUTOIMMUNE RETINOPATHY.

Journal Article Retin Cases Brief Rep · September 1, 2021 PURPOSE: To demonstrate a rapid improvement of recalcitrant cystoid macular edema (CME) and perivascular leakage, in a patient with non-paraneoplastic autoimmune retinopathy and autoimmune optic neuropathy after treatment with sarilumab, a human anti-inter ... Full text Link to item Cite

Visual Acuity in Retinal Vein Occlusion, Diabetic, and Uveitic Macular Edema: Central Subfield Thickness and Ellipsoid Zone Analysis.

Journal Article Ophthalmol Retina · July 2021 PURPOSE: This study assessed relationships between best-corrected visual acuity (BCVA), central subfield thickness (CST), and ellipsoid zone (EZ) integrity in macular edema (ME) patients. DESIGN: Post hoc analysis of 6 clinical trials, which included verif ... Full text Link to item Cite

Foveal Tuft.

Conference Retina · July 1, 2021 Full text Link to item Cite

Assessing the Retinal Microvasculature in Individuals With Early and Late-Onset Alzheimer's Disease.

Journal Article Ophthalmic Surg Lasers Imaging Retina · June 2021 BACKGROUND AND OBJECTIVE: To evaluate retinal microvascular changes in early and late-onset Alzheimer's disease (AD). PATIENTS AND METHODS: Eighty-six eyes of 50 late-onset AD participants, 27 eyes of 15 early onset AD participants, and 111 eyes of 57 cogn ... Full text Link to item Cite

Inpatient Ophthalmology Consultations.

Journal Article Med Clin North Am · May 2021 Comprehensive patient care requires an integrated approach that often includes different specialties. Of these specialties, Ophthalmology stands out with its variable pathologic conditions, unique tools, and special examination techniques, which are not pa ... Full text Link to item Cite

LONGITUDINAL FOLLOW-UP OF TUBERCULAR SERPIGINOUS-LIKE CHOROIDITIS USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Journal Article Retina · April 1, 2021 PURPOSE: To analyze and describe serial follow-up of choriocapillaris alterations in tubercular serpiginouslike choroiditis (SLC) using optical coherence tomography angiography (OCTA) and to compare it with multimodal imaging. METHODS: In this prospective ... Full text Link to item Cite

Frequency of Urgent or Emergent Vitreoretinal Surgical Procedures in the United States During the COVID-19 Pandemic.

Journal Article JAMA Ophthalmol · April 1, 2021 IMPORTANCE: The American Academy of Ophthalmology (AAO) indicated that urgent or emergent vitreoretinal surgical procedures should continue during the coronavirus disease 2019 (COVID-19) pandemic. Although decreases in the frequency of critical procedures ... Full text Link to item Cite

Choroidal Structural Analysis in Alzheimer Disease, Mild Cognitive Impairment, and Cognitively Healthy Controls.

Journal Article Am J Ophthalmol · March 2021 PURPOSE: To assess choroidal structural parameters in symptomatic Alzheimer disease (AD), mild cognitive impairment (MCI), and cognitively healthy control subjects. DESIGN: Prospective cross-sectional study. METHODS: This study took place in an outpatient ... Full text Open Access Link to item Cite

Characterization of Retinal Microvascular and Choroidal Structural Changes in Parkinson Disease.

Journal Article JAMA Ophthalmol · February 1, 2021 IMPORTANCE: Noninvasive retinal imaging may detect structural changes associated with Parkinson disease (PD) and may represent a novel biomarker for disease detection. OBJECTIVE: To characterize alterations in the structure and microvasculature of the reti ... Full text Link to item Cite

The application of optical coherence tomography angiography in Alzheimer's disease: A systematic review.

Journal Article Alzheimers Dement (Amst) · 2021 INTRODUCTION: Discovering non-invasive and easily acquired biomarkers that are conducive to the accurate diagnosis of dementia is an urgent area of ongoing clinical research. One promising approach is retinal imaging, as there is homology between retinal a ... Full text Link to item Cite

Reproducibility of Retinal Vascular Phenotypes Obtained with Optical Coherence Tomography Angiography: Importance of Vessel Segmentation

Conference Lecture Notes in Computer Science Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics · January 1, 2021 Optical coherence tomography angiography (OCTA) is a non-invasive imaging method that can visualize the finest vascular networks in the human retina. OCTA image analysis has been successfully applied to the investigation of retinal vascular diseases of the ... Full text Cite

Retinal vascular changes in Parkinson's disease on ultra-widefield retinal imaging

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · 2021 Cite

Multimodal imaging of type 2 acute macular neuroretinopathy in a young woman.

Journal Article Digit J Ophthalmol · 2021 We report a case of type 2 acute macular neuroretinopathy (AMN) that occurred in an otherwise healthy 22-year-old white woman taking oral contraceptives and consuming large quantities of caffeinated coffee. The patient presented with a teardrop-shaped scot ... Full text Link to item Cite

Repeatability of Peripapillary Optical Coherence Tomography Angiography Parameters in Older Adults.

Journal Article J Vitreoretin Dis · 2021 PURPOSE: This work assesses the intrasession repeatability of capillary perfusion density (CPD) and capillary flux index (CFI) measurements on peripapillary optical coherence tomography angiography (OCTA) in healthy eyes of older adults. METHODS: In this c ... Full text Link to item Cite

The relationship between pigment epithelial detachment and visual outcome in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.

Journal Article Eye (Lond) · December 2020 BACKGROUND/OBJECTIVES: To compare the detailed optical coherence tomography (OCT)-based morphological parameters of pigment epithelial detachment (PED) in eyes presenting with neovascular age-related macular degeneration (nAMD) and polypoidal choroidal vas ... Full text Link to item Cite

Association of OCT Angiography Parameters With Age in Cognitively Healthy Older Adults.

Journal Article Ophthalmic Surg Lasers Imaging Retina · December 1, 2020 BACKGROUND AND OBJECTIVE: To evaluate the association of changes in retinal anatomy and microvasculature with age and sex in cognitively healthy older adults. PATIENTS AND METHODS: Cross-sectional study of cognitively healthy subjects aged 50 years and old ... Full text Link to item Cite

Effects of Long-Term DME Control With 0.2 µg/Day Fluocinolone Acetonide Implant on Quality of Life: An Exploratory Analysis From the FAME Trial.

Journal Article Ophthalmic Surg Lasers Imaging Retina · November 1, 2020 BACKGROUND AND OBJECTIVE: Exploratory investigation of the effect of diabetic macular edema (DME) control with the 0.2 µg/day fluocinolone acetonide (FAc) intravitreal implant on quality of life (QOL) outcomes. PATIENTS AND METHODS: Post-hoc analysis of pa ... Full text Link to item Cite

AUTOLOGOUS RETINAL TRANSPLANTATION AS A PRIMARY TREATMENT FOR LARGE CHRONIC MACULAR HOLES.

Journal Article Retina · October 2020 PURPOSE: To report the outcomes of autologous neurosensory retinal transplant as a primary treatment for patients with large chronic macular holes and evaluate the safety and feasibility of the procedure. DESIGN: Retrospective study, consecutive case serie ... Full text Link to item Cite

Multiple Myeloma Presenting as Recalcitrant Macular Edema.

Journal Article J Vitreoretin Dis · June 2020 PURPOSE: This article presents an unusual case of ocular involvement of multiple myeloma masquerading as macular edema associated with diabetic retinopathy. METHODS: A report of a single case. RESULTS: The presence of concomitant type 2 diabetes and scatte ... Full text Link to item Cite

Time to disease recurrence in noninfectious uveitis following long-acting injectable fluocinolone acetonide implant.

Journal Article Graefes Arch Clin Exp Ophthalmol · May 2020 PURPOSE: To determine the time to disease recurrence with long-acting injectable fluocinolone acetonide implant (FAi) for noninfectious intermediate, posterior, and panuveitis. METHODS: This was a retrospective study of patients with at least 12 months of ... Full text Link to item Cite

CHORIOCAPILLARIS FLOW VOIDS IN CRYPTOCOCCAL CHOROIDITIS USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Journal Article Retin Cases Brief Rep · 2020 PURPOSE: To report an unusual case of cryptococcal choroiditis and highlight the multimodal imaging findings, particularly the choriocapillaris flow voids using optical coherence tomography angiography. METHODS: Retrospective review of the clinical course ... Full text Link to item Cite

Appearance of pediatric choroidal neovascular membranes on optical coherence tomography angiography.

Journal Article Graefes Arch Clin Exp Ophthalmol · January 2020 PURPOSE: Compared with fluorescein angiography (FA), the gold standard for diagnosing choroidal neovascularization (CNV) activity, optical coherence tomography angiography (OCTA) is non-invasive without risks associated with fluorescein dye use, and may be ... Full text Link to item Cite

Comparison of wide-field swept source optical coherence tomography angiography and fundus autofluorescence in tubercular serpiginous-like choroiditis.

Journal Article Indian J Ophthalmol · January 2020 PURPOSE: To evaluate the potential clinical utility of wide-field swept source optical coherence tomography angiography (SS-OCTA) using a prototype device compared to a wide-field fundus autofluorescence (FAF) for analysis of the disease activity in eyes w ... Full text Link to item Cite

The Evolution of Fibrosis and Atrophy and Their Relationship with Visual Outcomes in Asian Persons with Neovascular Age-Related Macular Degeneration.

Journal Article Ophthalmol Retina · December 2019 PURPOSE: To describe the rate of development and progression of fibrosis and macular atrophy (MA) and their relationship with 1-year visual outcomes in Asian participants with neovascular age-related macular degeneration (nAMD). DESIGN: Review of images co ... Full text Link to item Cite

Quantification of retinal microvasculature and neurodegeneration changes in branch retinal vein occlusion after resolution of cystoid macular edema on optical coherence tomography angiography.

Journal Article Indian J Ophthalmol · November 2019 PURPOSE: To compare foveal avascular zone (FAZ) area and circularity, ganglion cell layer (GCL) thickness, retinal perfusion density (PD), and vessel density (VD) in eyes with branch retinal vein occlusion (BRVO) after resolution of cystoid macular edema ( ... Full text Link to item Cite

Correlation of OCTA and Volumetric MRI in Mild Cognitive Impairment and Alzheimer's Disease.

Journal Article Ophthalmic Surg Lasers Imaging Retina · November 1, 2019 BACKGROUD AND OBJECTIVE: To evaluate the relationship between retinal microvascular parameters on optical coherence tomography angiography (OCTA) and neurodegenerative changes assessed by measurement of brain volume on volumetric magnetic resonance imaging ... Full text Link to item Cite

Autologous Retinal Transplant for Refractory Macular Holes: Multicenter International Collaborative Study Group.

Journal Article Ophthalmology · October 2019 PURPOSE: To report the structural and functional outcomes of autologous neurosensory retinal transplant for closure of refractory large macular holes (MHs). DESIGN: Multicenter, retrospective, consecutive case series. PARTICIPANTS: A total of 41 eyes of 41 ... Full text Link to item Cite

Deep learning algorithm for diagnosis of Alzheimer's disease using multimodal retinal imaging

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · July 1, 2019 Link to item Cite

Retinal Microvascular and Neurodegenerative Changes in Alzheimer's Disease and Mild Cognitive Impairment Compared with Control Participants.

Journal Article Ophthalmol Retina · June 2019 PURPOSE: Evaluate and compare the retinal microvasculature in the superficial capillary plexus (SCP) in Alzheimer's disease (AD), mild cognitive impairment (MCI), and cognitively intact controls using OCT angiography. OCT parameters were also compared. DES ... Full text Link to item Cite

Association of Retinal Inner Layer Disorganization With Ultra-Widefield Fluorescein Angiographic Features and Visual Acuity in Branch Retinal Vein Occlusion.

Journal Article Ophthalmic Surg Lasers Imaging Retina · June 1, 2019 BACKGROUND AND OBJECTIVE: To assess the impact of the disorganization of retinal inner layers (DRIL) on visual acuity (VA) and its correlation with ischemic index (IsI) on ultra-widefield fluorescein angiography (UWFFA) in eyes with acute, treatment-naïve ... Full text Link to item Cite

Accuracy of Tonopen Versus iCare in Human Cadaveric Eyes With Edematous Corneas Over a Wide Range of Intraocular Pressures.

Journal Article J Glaucoma · May 2019 PURPOSE: The purpose of this study was to compare the accuracy of 2 portable tonometers, Tonopen and iCare, in extreme corneal edema, while also accounting for the location of pressure measurement over a wide range of intraocular pressure (IOP). METHODS: U ... Full text Link to item Cite

Is OCT Angiography Useful in Neurodegenerative Diseases?

Journal Article Ophthalmic Surg Lasers Imaging Retina · May 1, 2019 Full text Link to item Cite

Use of Letermovir as Salvage Therapy for Drug-Resistant Cytomegalovirus Retinitis.

Journal Article Antimicrob Agents Chemother · March 2019 Treatment options for drug-resistant cytomegalovirus (CMV) are limited. Letermovir is a novel antiviral recently approved for CMV prophylaxis following hematopoietic cell transplantation, but its efficacy in other settings is unknown. We recently used lete ... Full text Open Access Link to item Cite

Pneumatic Retinopexy Experience and Outcomes of Vitreoretinal Fellows in the United States: A Multicenter Study.

Journal Article Ophthalmol Retina · February 2019 OBJECTIVE: To evaluate the outcomes of patients undergoing pneumatic retinopexy (PR) performed by vitreoretinal fellows at 6 academic centers in the United States. DESIGN: Retrospective, multicenter, consecutive case series. PARTICIPANTS: 483 patients with ... Full text Link to item Cite

Rare Complication of Sclerochoroidal Calcifications.

Journal Article JAMA Ophthalmol · January 1, 2019 Full text Link to item Cite

Reply.

Journal Article Ophthalmol Retina · January 2019 Full text Link to item Cite

Effect of fluocinolone acetonide 0.2 μg/day implant on the decision to drive in patients with diabetic macular oedema: a report from the FAME study.

Journal Article BMJ Open Ophthalmol · 2019 OBJECTIVE: This study aimed to determine whether treatment with the 0.2 µg/day fluocinolone acetone implant (FAc; ILUVIEN, Alimera Sciences) and the associated improvements in best-corrected visual acuity (BCVA) and central subfield thickness (CST) demonst ... Full text Link to item Cite

Inflammatory and idiopathic choroidal neovascularization

Chapter · January 1, 2019 This chapter reviews the imaging findings for diagnosis and monitoring treatment response of inflammatory pediatric choroidal neovascular membranes. ... Full text Cite

White dot syndromes

Chapter · January 1, 2019 This chapter reviews the clinical features and imaging findings of white dot syndrome in the pediatric population and the treatment options available. ... Full text Cite

Vogt-koyanagi harada syndrome

Chapter · January 1, 2019 This chapter reviews the clinical presentation, imaging characteristics and treatment options for Vogt-Koyanagi-Harada (VKH) syndrome. VKH syndrome is a multisystem disease with a clinical course comprising four stages; aggressive treatment may shorten the ... Full text Cite

Infectious retinitis: TORCH syndrome

Chapter · January 1, 2019 This chapter describes the clinical features, imaging and OCT findings, and treatment of eyes in children with TORCH syndrome (Toxoplasmosis, Other infections [syphilis, varicella-zoster virus, parvovirus B19], Rubella, Cytomegalovirus infection, and Herpe ... Full text Cite

Pediatric intermediate uveitis

Chapter · January 1, 2019 This chapter reviews cystoid macular edema and retinal vasculitis, common complications of pediatric uveitis. Anatomic features of juvenile idiopathic arthritis, multiple sclerosis, tubulointerstitial nephritis and uveitis (TINU), pars planitis, and Behçt ... Full text Cite

Choroidal granulomas: Tuberculosis and sarcoidosis

Chapter · January 1, 2019 This chapter reviews the distinct optical coherence tomography (OCT) imaging characteristics of choroidal granulomas associated with tuberculosis and sarcoidosis. Clinical features and treatment of these choroidal granulomas are reviewed. ... Full text Cite

Current role of optical coherence tomography angiography: Expert panel discussion.

Journal Article Indian J Ophthalmol · December 2018 Optical coherence tomography (OCT) angiography is a promising technique that provides depth resolved images of blood flow in the retina and choroid with levels of detail far exceeding that obtained with older forms of imaging and offers several advantages ... Full text Link to item Cite

Association of Disorganization of Retinal Inner Layers with Ischemic Index and Visual Acuity in Central Retinal Vein Occlusion.

Journal Article Ophthalmol Retina · November 2018 PURPOSE: To determine whether disorganization of retinal inner layers (DRIL) on optical coherence tomography (OCT) is associated with ischemia on ultra-widefield fluorescein angiography (UWFFA) and with visual outcomes in eyes with acute, treatment-naïve c ... Full text Link to item Cite

The role of cystoid macular edema as a marker in the progression of non-paraneoplastic autoimmune retinopathy.

Journal Article Graefes Arch Clin Exp Ophthalmol · October 2018 PURPOSE: To determine the relationship between cystoid macular edema (CME) and disease severity and progression in non-paraneoplastic autoimmune retinopathy (npAIR). METHODS: A retrospective study was conducted on patients seen between 2008 and 2016 with n ... Full text Link to item Cite

COMBINED AUTOLOGOUS TRANSPLANTATION OF NEUROSENSORY RETINA, RETINAL PIGMENT EPITHELIUM, AND CHOROID FREE GRAFTS.

Journal Article Retina · September 2018 PURPOSE: To evaluate the feasibility and initial functional and anatomical outcomes of transplanting a full-thickness free graft of choroid and retinal pigment epithelium (RPE), along with neurosensory retina in advanced fibrosis and atrophy associated wit ... Full text Link to item Cite

Diagnostic and Therapeutic Challenges.

Journal Article Retina · September 2018 Full text Link to item Cite

Bilateral recurrent macular holes.

Journal Article Am J Ophthalmol Case Rep · September 2018 PURPOSE: To report an unusual case of bilateral recurrent full-thickness macular holes (FTMH) in both eyes of a single patient over a 15-year period, with a total of 3 FTMH in the right eye and 2 in the left eye. Each FTMH was successfully treated with vit ... Full text Link to item Cite

Conjunctival Dehiscence and Scleral Necrosis following Iodine-125 Plaque Brachytherapy for Uveal Melanoma: A Report of 3 Cases.

Journal Article Ocul Oncol Pathol · September 2018 BACKGROUND/AIMS: Plaque brachytherapy is currently the most common treatment for uveal melanoma and has many known potential complications. Here we present 3 cases of early conjunctival and scleral necrosis following iodine-125 plaque. METHODS: This study ... Full text Link to item Cite

Treatment Response in Sympathetic Ophthalmia as Assessed by Widefield OCT Angiography.

Journal Article Ophthalmic Surg Lasers Imaging Retina · September 1, 2018 The authors report the widefield montage swept-source optical coherence tomography angiography (OCTA) findings in a 36-year-old male with sympathetic ophthalmia and illustrate the presence of multiple small areas of choriocapillaris flow voids that likely ... Full text Link to item Cite

Assessment of Differences in Retinal Microvasculature Using OCT Angiography in Alzheimer's Disease: A Twin Discordance Report.

Journal Article Ophthalmic Surg Lasers Imaging Retina · June 1, 2018 The authors report the optical coherence tomography angiography (OCTA)-based comparative assessment of the retinal microvasculature in a rare pair of 96-year-old female monozygotic twins discordant for Alzheimer's disease (AD). Using automated mapping of t ... Full text Link to item Cite

Argus II retinal prosthesis system: a review of patient selection criteria, surgical considerations, and post-operative outcomes.

Journal Article Clin Ophthalmol · 2018 Retinitis pigmentosa (RP) is a group of heterogeneous inherited retinal degenerative disorders characterized by progressive rod and cone dysfunction and ensuing photoreceptor loss. Many patients suffer from legal blindness by their 40s or 50s. Artificial v ... Full text Link to item Cite

Multifocal iris melanoma in a 2-year-old managed with I-125 plaque brachytherapy.

Journal Article J AAPOS · October 2017 We report a 23-month-old patient presenting with multifocal iris melanoma who underwent plaque brachytherapy with full corneal coverage. The lesion demonstrated several high-risk clinical and histopathologic features associated with iris melanoma in adults ... Full text Link to item Cite

Cystoid Macular Edema as a Marker in the Progression of Autoimmune Retinopathy

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · June 1, 2017 Link to item Cite

Association of Disorganization of Retinal Inner Layers With Visual Acuity In Eyes With Uveitic Cystoid Macular Edema.

Journal Article Am J Ophthalmol · May 2017 PURPOSE: To determine whether disorganization of retinal inner layers (DRIL) assessed by spectral-domain optical coherence tomography (SDOCT) correlates with visual acuity (VA) in eyes with uveitic cystoid macular edema (CME). DESIGN: Secondary analysis of ... Full text Link to item Cite

Sequential Sterile Intraocular Inflammation Associated With Consecutive Intravitreal Injections of Aflibercept and Ranibizumab.

Journal Article Ophthalmic Surg Lasers Imaging Retina · May 1, 2017 The authors report the unique response of two patients treated for cystoid macular edema (CME) secondary to central retinal vein occlusion (CRVO) who developed sequential episodes of likely sterile inflammatory responses following separate intravitreal inj ... Full text Link to item Cite

Outcomes of 27-Gauge Vitrectomy-Assisted Choroidal and Subretinal Biopsy.

Journal Article Ophthalmic Surg Lasers Imaging Retina · May 1, 2017 BACKGROUND AND OBJECTIVE: To report the initial experience of 27-gauge vitrectomy-assisted choroidal and subretinal biopsy PATIENTS AND METHODS: Retrospective, interventional case series. Eighteen eyes of 18 patients undergoing 27-gauge vitrectomy-assisted ... Full text Link to item Cite

Intraoperative 4-Dimensional Microscope-Integrated Optical Coherence Tomography-Guided 27-Gauge Transvitreal Choroidal Biopsy for Choroidal Melanoma.

Journal Article Retina · April 2017 PURPOSE: We describe two cases of intraoperative 4D microscope–integrated swept source optical coherence tomography (4D MIOCT) guided 27-gauge transvitreal retinochoroidal biopsy for choroidal melanoma. METHODS: Two 68-year-old females with choroidal melan ... Full text Link to item Cite

Association of Pediatric Choroidal Neovascular Membranes at the Temporal Edge of Optic Nerve and Retinochoroidal Coloboma.

Journal Article Am J Ophthalmol · February 2017 PURPOSE: To describe the characteristics of pediatric choroidal neovascular membranes (CNVs) associated with retinochoroidal and optic nerve coloboma using optical coherence tomography (OCT) and their response to treatment. DESIGN: Retrospective case serie ... Full text Link to item Cite

Spontaneous Closure of Full-Thickness Macular Hole With Epiretinal Membrane in Vitrectomized Eyes: Case Series and Review of Literature.

Journal Article Ophthalmic Surg Lasers Imaging Retina · February 1, 2017 The authors describe three vitrectomized eyes that each subsequently developed a full-thickness macular hole (FTMH) that then spontaneously closed and summarize the current literature reporting these rare events. Clinical history, imaging, and course of th ... Full text Link to item Cite

Peripapillary retinal splitting visualized on OCT in glaucoma and glaucoma suspect patients.

Journal Article PLoS One · 2017 PURPOSE: To identify the risk factors for development of peripapillary retinal splitting (schisis) in patients with glaucoma or suspicion of glaucoma. SETTING: Glaucoma Clinic, Department of Ophthalmology, Northwestern University Feinberg School of Medicin ... Full text Link to item Cite

The Original Theory of Constitutionalism

Journal Article Yale Law Journal · 2017 Link to item Cite

Fundus Autofluorescence Patterns of Submacular Fluid Resolution Following Repair of Macula-Involving Rhegmatogenous Retinal Detachments.

Conference Ophthalmic Surg Lasers Imaging Retina · November 1, 2016 BACKGROUND AND OBJECTIVE: Submacular fluid (SMF) can persist for months to years following rhegmatogenous retinal detachment (RD) repair. The authors' objective was to describe fundus autofluorescence (FAF) and optical coherence tomography (OCT) findings a ... Full text Link to item Cite

Wide field of view swept-source optical coherence tomography for peripheral retinal disease.

Journal Article Br J Ophthalmol · October 2016 BACKGROUND/AIMS: To assess peripheral retinal lesions and the posterior pole in single widefield optical coherence tomography (OCT) volumes. METHODS: A wide field of view (FOV) swept-source OCT (WFOV SSOCT) system was developed using a commercial swept-sou ... Full text Link to item Cite

Dehydrated Allogenic Human Amniotic Membrane Graft for Conjunctival Surface Reconstruction Following Removal of Exposed Scleral Buckle.

Journal Article Ophthalmic Surg Lasers Imaging Retina · October 1, 2016 A 54-year-old male developed symptomatic scleral buckle exposure 16 years after placement and presented with large conjunctival defects with fibrosed edges. Following surgical removal of the buckle elements, primary conjunctival closure could not be achiev ... Full text Link to item Cite

Portable Optical Coherence Tomography Detection or Confirmation of Ophthalmoscopically Invisible or Indeterminate Active Retinoblastoma.

Journal Article Ophthalmic Surg Lasers Imaging Retina · October 1, 2016 Portable, hand-held optical coherence tomography (OCT) revealed three clinically relevant yet not ophthalmoscopically detected or confirmed manifestations of retinoblastoma in a single patient with familial bilateral disease. Specifically, OCT showed new r ... Full text Link to item Cite

Dynamic Imaging of a Pigmented Free-Floating Vitreous Cyst.

Journal Article Ophthalmic Surg Lasers Imaging Retina · October 1, 2016 The authors present an incidentally noted pigmented anterior vitreous cyst in an asymptomatic male adult. Observation was elected. Stability during the course of 2 years and mobility of the vitreous cyst using dynamic imaging are demonstrated. [Ophthalmic ... Full text Link to item Cite

Regional Changes in Choroidal Thickness in Branch Retinal Artery Occlusion.

Journal Article Ophthalmic Surg Lasers Imaging Retina · September 1, 2016 BACKGROUND AND OBJECTIVE: To assess regional changes in choroidal thickness in the affected temporal hemifield of eyes with branch retinal artery occlusion (BRAO) compared to the unaffected temporal hemifield of the same eye and to fellow eyes. PATIENTS AN ... Full text Link to item Cite

Topography of the Vitreoretinal Interface in Vitreomacular Traction Syndrome

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · September 1, 2016 Link to item Cite

Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images.

Journal Article J Biomed Opt · July 1, 2016 We introduce a metric in graph search and demonstrate its application for segmenting retinal optical coherence tomography (OCT) images of macular pathology. Our proposed “adjusted mean arc length” (AMAL) metric is an adaptation of the lowest mean arc lengt ... Full text Link to item Cite

Impact of the Learning Curve on Intraoperative Surgical Time in Femtosecond Laser-Assisted Cataract Surgery.

Journal Article J Refract Surg · May 1, 2016 PURPOSE: To analyze the impact of learning curve on operating room (OR) times, femtosecond laser times, procedure time (time for laser and non-laser steps combined), and surgical time (procedure time minus transfer and preoperative times) during transition ... Full text Link to item Cite

Choroidal Thickness and En Face Optical Coherence Tomography Imaging in Autoimmune Retinopathy.

Journal Article Ophthalmic Surg Lasers Imaging Retina · April 1, 2016 A 57-year-old white woman developed autoimmune retinopathy (AIR) in both eyes associated with bilateral autoimmune sensorineural hearing loss. Laboratory testing was positive for 68kDa (heat-shock protein) and 136kDa (human interstitial retinoid-binding pr ... Full text Link to item Cite

A Comparative Study of Rebound Tonometry With Tonopen and Goldmann Applanation Tonometry Following Vitreoretinal Surgery.

Journal Article Am J Ophthalmol · January 2016 PURPOSE: To investigate agreement in intraocular pressure (IOP) measurements among Icare rebound tonometry, Tonopen tonometry, and Goldmann applanation tonometry following vitreoretinal surgery. DESIGN: Reliability analysis of tonometers. METHODS: Fifty-ey ... Full text Link to item Cite

Femtosecond laser-assisted cataract surgery--current status and future directions.

Journal Article Surv Ophthalmol · 2016 Femtosecond laser-assisted cataract surgery (FLACS) putatively offers several advantages over conventional phacoemulsification. We review the current status of FLACS and discuss the evolution of femtosecond lasers in cataract surgery and the currently avai ... Full text Link to item Cite

Role of aflibercept for macular edema following branch retinal vein occlusion: comparison of clinical trials.

Journal Article Clin Ophthalmol · 2016 For years, the standard of care for branch-retinal-vein-occlusion-associated macular edema was initial observation followed by grid-pattern laser photocoagulation for persistent edema. Newer pharmacologic options have revolutionized the management of branc ... Full text Link to item Cite

Assessment of Foveal Microstructure and Foveal Lucencies Using Optical Coherence Tomography Radial Scans Following Macular Hole Surgery.

Journal Article Am J Ophthalmol · November 2015 PURPOSE: To evaluate the foveal microstructure using high-density (24-line) radial scans and their correlation with visual recovery following macular hole surgery. DESIGN: Retrospective, consecutive, interventional case series. METHODS: Forty-five eyes of ... Full text Link to item Cite

Transitioning to intravitreal aflibercept following a previous treat-and-extend dosing regimen in neovascular age-related macular degeneration: 24-month results.

Journal Article Eye (Lond) · September 2015 PURPOSE: To evaluate frequency of injections, visual and anatomical outcomes of neovascular age-related macular degeneration (nAMD) patients transitioned to intravitreal aflibercept after failure to extend treatment interval beyond 8 weeks with prior intra ... Full text Link to item Cite

Quantification of Change in Pigment Epithelial Detachment Volume and Morphology After Transition to Intravitreal Aflibercept in Eyes With Recalcitrant Neovascular AMD: 18-Month Results.

Journal Article Ophthalmic Surg Lasers Imaging Retina · June 2015 BACKGROUND AND OBJECTIVE: To quantitatively evaluate the change in pigment epithelial detachment (PED) morphology on spectral-domain optical coherence tomography (SD-OCT) 18 months after the transition to intravitreal aflibercept in patients with neovascul ... Full text Link to item Cite

Ultra wide-field swept-source optical coherence tomography for peripheral eye disease

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · June 1, 2015 Link to item Cite

Brachytherapy in Neovascular AMD

Journal Article Current Ophthalmology Reports · March 1, 2015 Neovascular age-related macular degeneration (AMD) has a complex pathophysiology, and although anti-VEGF therapy has been one of the most significant and successful advances, it is not effective for all patients with neovascular AMD. The potential role of ... Full text Cite

Bilateral angle closure following use of a weight loss combination agent containing topiramate.

Journal Article J Glaucoma · 2015 PURPOSE: To report a unique case of topiramate-induced bilateral angle closure following ingestion of a recently introduced weight loss medication containing topiramate, and to describe its management. METHODS: Case report of a 39-year-old, otherwise healt ... Full text Link to item Cite

Incomplete femtosecond laser-assisted capsulotomy and lens fragmentation due to emulsified silicone oil in the anterior chamber.

Journal Article J Cataract Refract Surg · December 2014 We report 2 cases involving femtosecond laser-assisted cataract surgery following a retinal-detachment repair performed 1 and 2 years earlier using silicone oil endotamponade that was subsequently removed. Preoperative slitlamp examination did not show emu ... Full text Link to item Cite

Intraoperative reverse pupillary block during femtosecond laser-assisted cataract surgery in a patient with phacomorphic angle closure.

Journal Article J Cataract Refract Surg · November 2014 UNLABELLED: We report a patient with phacomorphic angle closure having femtosecond laser-assisted cataract surgery. A staged procedure was followed to achieve mydriasis and deepen the anterior chamber with bisulfate-free epinephrine (epi-Shugarcaine) and a ... Full text Link to item Cite

Visual and anatomical outcomes following intravitreal aflibercept in eyes with recalcitrant neovascular age-related macular degeneration: 12-month results.

Journal Article Eye (Lond) · July 2014 PURPOSE: To describe the efficacy of intravitreal aflibercept on 12-month visual and anatomical outcomes in patients with neovascular age-related macular degeneration (AMD) recalcitrant to prior monthly intravitreal bevacizumab or ranibizumab. METHODS: Non ... Full text Link to item Cite

Femtosecond cataract laser capsulotomy enabling optic capture and secondary sulcus iol insertion in an eye with traumatic aniridia and aphakia.

Journal Article J Refract Surg · June 2014 PURPOSE: To describe a surgical technique and intraoperative modifications to create a secondary capsulotomy using the femtosecond cataract laser in an eye with traumatic aphakia and aniridia. METHODS: The expanded use of the femtosecond cataract laser (Ca ... Full text Link to item Cite

Autoimmune retinopathy and antiretinal antibodies: a review.

Journal Article Retina · May 2014 PURPOSE: To review the current state for diagnosis and management of autoimmune retinopathy. METHODS: A review of the literature was performed, encompassing autoimmune retinopathy including paraneoplastic retinopathy (cancer-associated retinopathy, melanom ... Full text Link to item Cite

Intraoperative vertical gas breakthrough during clear corneal incision creation with the femtosecond cataract laser.

Journal Article J Cataract Refract Surg · April 2014 UNLABELLED: We report the occurrence and management of intraoperative vertical gas breakthrough during clear corneal incision creation with the femtosecond laser (Catalys) in 2 patients. Both eyes were managed by creation of a keratome incision, and the su ... Full text Link to item Cite

Comparison of morphologic features of clear corneal incisions created with a femtosecond laser or a keratome.

Journal Article J Cataract Refract Surg · April 2014 PURPOSE: To compare the morphology of clear corneal incisions (CCIs) created with a femtosecond laser (Catalys) or a keratome (2.65 mm steel) during phacoemulsification using anterior segment optical coherence tomography (AS-OCT) and analyze the intended v ... Full text Link to item Cite

Isolated abducens nerve palsy following neonatal hepatitis B vaccination.

Journal Article J AAPOS · February 2014 We report a case of sudden-onset abducens nerve palsy in an otherwise healthy 8-day-old boy following neonatal hepatitis B vaccination. A complete workup, including magnetic resonance imaging of the brain and orbits revealed no abnormalities. The patient r ... Full text Link to item Cite

A pilot quantitative study of topographic correlation between reticular pseudodrusen and the choroidal vasculature using en face optical coherence tomography.

Journal Article PLoS One · 2014 PURPOSE: To analyze the topographic correlation between reticular pseudodrusen (RPD) visualized on infrared reflectance (IR) and choroidal vasculature using en-face volumetric spectral-domain optical coherence tomography (SD-OCT). METHODS: A masked observe ... Full text Link to item Cite

Endothelial damage with two DSAEK insertion techniques performed by a novice corneal surgeon in residency training: a comparative analysis.

Journal Article Cornea · January 2014 PURPOSE: The aim was to determine which of 2 commonly used nonfold donor insertion techniques was advantageous for initial Descemet stripping automated endothelial keratoplasty (DSAEK) cases. METHODS: This involved an ex vivo, prospective comparative case ... Full text Link to item Cite

Diagnosis of glaucoma and detection of glaucoma progression using spectral domain optical coherence tomography.

Journal Article Curr Opin Ophthalmol · March 2013 PURPOSE OF REVIEW: With the rapid adoption of spectral domain optical coherence tomography (SDOCT) in clinical practice and the recent advances in software technology, there is a need for a review of the literature on glaucoma detection and progression ana ... Full text Link to item Cite

Quantitative analysis of anterior chamber following peripheral laser iridotomy using Pentacam in eyes with primary angle closure.

Journal Article Eur J Ophthalmol · May 14, 2012 Purpose. To quantify the effects of laser peripheral iridotomy (LPI) on peripheral anterior chamber depth (PACD), central internal anterior chamber depth (CACD), and anterior chamber volume (ACV) using Rotating Scheimpflug Imaging System, i.e., Pentacam, o ... Full text Link to item Cite

Modified technique for removal of Soemmerring ring and in-the-bag secondary intraocular lens placement in aphakic eyes.

Journal Article J Cataract Refract Surg · May 2012 UNLABELLED: We describe modifications to previously described techniques for evacuation of Soemmerring ring during secondary intraocular lens (IOL) implantation in aphakic eyes following previous pediatric cataract surgery. A new anterior capsulotomy is in ... Full text Link to item Cite

Detection of progressive retinal nerve fiber layer thickness loss with optical coherence tomography using 4 criteria for functional progression.

Journal Article J Glaucoma · 2012 PURPOSE: To compare the rates of retinal nerve fiber layer (RNFL) thickness loss using optical coherence tomography (OCT) in progressing versus nonprogressing eyes using 4 methods to define functional progression. METHODS: Normal and glaucomatous eyes with ... Full text Link to item Cite

Clinical applications of Scheimpflug imaging in cataract surgery.

Journal Article Saudi J Ophthalmol · January 2012 Since the Scheimpflug principle was first described over a century ago, there has been a great interest among ophthalmologists for the use of Scheimpflug camera in anterior segment imaging. Scheimpflug imaging has since advanced significantly and modern da ... Full text Link to item Cite

Comparing rates of retinal nerve fibre layer loss with GDxECC using different methods of visual-field progression.

Journal Article Br J Ophthalmol · August 2011 BACKGROUND: This prospective analysis was designed to examine the rate of RNFL loss using scanning laser polarimetry (GDx enhanced corneal compensation (GDxECC)) in progressing versus non-progressing eyes using various methods to define functional progress ... Full text Link to item Cite

The impact of retardance pattern variability on nerve fiber layer measurements over time using GDx with variable and enhanced corneal compensation.

Journal Article Invest Ophthalmol Vis Sci · June 23, 2011 PURPOSE: To examine the impact of retardance pattern variability on retinal nerve fiber layer (RNFL) measurements over time using scanning laser polarimetry with variable (GDxVCC) and enhanced corneal compensation (GDxECC; both by Carl Zeiss Meditec, Inc., ... Full text Link to item Cite

Comparison of Scheimpflug imaging and spectral domain anterior segment optical coherence tomography for detection of narrow anterior chamber angles.

Journal Article Eye (Lond) · May 2011 PURPOSE: To compare the performance of anterior chamber volume (ACV) and anterior chamber depth (ACD) obtained using Scheimpflug imaging with angle opening distance (AOD500) and trabecular-iris space area (TISA500) obtained using spectral domain anterior s ... Full text Link to item Cite

Posterior corneal elevation after LASIK with three flap techniques as measured by Pentacam.

Journal Article J Refract Surg · April 2011 PURPOSE: To evaluate and compare posterior corneal changes using elevation data obtained from Pentacam (Oculus Optikgeräte GmbH) Scheimpflug imaging in eyes undergoing LASIK with three different modes of flap creation: IntraLase femtosecond laser FS60 (Abb ... Full text Link to item Cite

Detecting glaucomatous progression using GDx with variable and enhanced corneal compensation using Guided Progression Analysis.

Journal Article Br J Ophthalmol · April 2011 OBJECTIVE: To compare detection of glaucoma progression with scanning laser polarimetry using two methods for corneal compensation. METHODS: Normal, glaucoma suspects and glaucoma patients with 36 months' follow-up meeting the eligibility criteria were pro ... Full text Link to item Cite

The impact of intraocular pressure reduction on retinal ganglion cell function measured using pattern electroretinogram in eyes receiving latanoprost 0.005% versus placebo.

Journal Article Vision Res · January 28, 2011 PURPOSE: To evaluate the impact of intraocular (IOP) reduction on retinal ganglion cell (RGC) function measured using pattern electroretinogram optimized for glaucoma (PERGLA) in glaucoma suspect and glaucomatous eyes receiving latanoprost 0.005% versus pl ... Full text Link to item Cite

Quantification of change in axonal birefringence following surgical reduction in intraocular pressure.

Journal Article Ophthalmic Surg Lasers Imaging · 2011 BACKGROUND AND OBJECTIVE: the purpose of this study was to examine the hypothesis that retinal nerve fiber layer (RNFL) birefringence increases following surgical reduction of intraocular pressure (IOP). PATIENTS AND METHODS: twenty-six glaucomatous eyes r ... Full text Link to item Cite

Reversal of retinal ganglion cell dysfunction after surgical reduction of intraocular pressure.

Journal Article Ophthalmology · December 2010 PURPOSE: The pattern electroretinogram optimized for glaucoma screening (PERGLA) is a noninvasive method of objectively measuring retinal ganglion cell (RGC) function. This study was undertaken to quantify the RGC response to intraocular pressure (IOP) red ... Full text Link to item Cite

Three-dimensional high-speed optical coherence tomography for diagnosis of hypotony maculopathy after glaucoma filtration surgery.

Journal Article J Glaucoma · August 2010 PURPOSE: To describe the clinical findings of hypotony maculopathy using 3-dimensional (3D) topography maps reconstructed from spectral domain optical coherence tomography (SD-OCT) imaging, and compare SD-OCT with time domain OCT (TD-OCT) for hypotony macu ... Full text Link to item Cite

Reversible Bleomycin Toxicity

Journal Article Medical Journal Armed Forces India · July 1, 2010 Full text Cite

Assessment of central corneal thickness in normal, keratoconus, and post-laser in situ keratomileusis eyes using Scheimpflug imaging, spectral domain optical coherence tomography, and ultrasound pachymetry.

Journal Article J Cataract Refract Surg · June 2010 PURPOSE: To compare the central corneal thickness (CCT) in normal eyes, eyes with keratoconus, and eyes after laser in situ keratomileusis (LASIK) using 3 methods. SETTING: Cornea Clinic, Grewal Eye Institute, Chandigarh, India. METHODS: In this study, CCT ... Full text Link to item Cite

Diffuse glaucomatous structural and functional damage in the hemifield without significant pattern loss.

Journal Article Arch Ophthalmol · November 2009 OBJECTIVES: To compare the retinal nerve fiber layer (RNFL) thickness and retinal sensitivity in the normal visual hemifield of glaucomatous eyes with localized visual field loss with those of normal eyes and eyes with suspected glaucoma, and to evaluate t ... Full text Link to item Cite

Diagnostic ability of Fourier-domain vs time-domain optical coherence tomography for glaucoma detection.

Journal Article Am J Ophthalmol · October 2009 PURPOSE: To compare retinal nerve fiber layer (RNFL) thickness assessments and the discriminating ability of Fourier-domain optical coherence tomography (FD-OCT) with that of time-domain optical coherence tomography (TD-OCT) for glaucoma detection. DESIGN: ... Full text Link to item Cite

Correlation of nuclear cataract lens density using Scheimpflug images with Lens Opacities Classification System III and visual function.

Journal Article Ophthalmology · August 2009 PURPOSE: To calculate the average lens density (ALD) and nuclear lens density (NLD) using Scheimpflug images and to determine their correlation with logarithmic minimal angle resolution (logMAR) best-corrected visual acuity (BCVA), contrast sensitivity (CS ... Full text Link to item Cite

Neural tube defects and herbal medicines containing lead: a possible relationship.

Journal Article Med Hypotheses · March 2009 Neural tube defects (NTDs) are the most common cause of potentially preventable congenital malformations in the human fetus. Even with the universal folate supplementation the incidence of NTDs remain higher is developing world than the industrialized coun ... Full text Link to item Cite

Corneal collagen crosslinking using riboflavin and ultraviolet-A light for keratoconus: one-year analysis using Scheimpflug imaging.

Journal Article J Cataract Refract Surg · March 2009 PURPOSE: To evaluate changes in corneal curvature, corneal elevation, corneal thickness, lens density, and foveal thickness after corneal collagen crosslinking with riboflavin and ultraviolet-A (UVA) light in eyes with progressive keratoconus. SETTING: Gre ... Full text Link to item Cite

Ocular toxoplasmosis presenting with focal retinal nerve fiber atrophy simulating glaucoma.

Journal Article J Glaucoma · February 2009 PURPOSE: We describe a patient with ocular hypertension and nonglaucomatous retinal nerve fiber layer (RNFL) atrophy associated with an ocular toxoplasmosis retinal lesion. PATIENT AND METHOD: Single case report. RESULTS: An RNFL defect was identified adja ... Full text Link to item Cite

Clinical applications of Scheimpflug imaging

Journal Article Expert Review of Ophthalmology · January 1, 2009 Since the Scheimpflug principle was first described more than a century ago, there has been great interest among ophthalmologists in the use of Scheimpflug cameras in anterior-segment imaging. Scheimpflug cameras have advanced significantly and modern-day ... Full text Cite

Scheimpflug imaging of pediatric posterior capsule rupture.

Journal Article Indian J Ophthalmol · 2009 We report a case of an 11-year-old boy who presented two days after blunt trauma to the left eye with a slingshot. On examination his best corrected visual acuity (BCVA) was 20/20 in the right eye and 20/400 in the left eye. Slit-lamp examination of the le ... Full text Link to item Cite

Evaluation of subconjunctival bevacizumab as an adjunct to trabeculectomy a pilot study.

Journal Article Ophthalmology · December 2008 PURPOSE: To determine whether bevacizumab can reduce bleb failure in patients undergoing first-time trabeculectomy for primary open-angle glaucoma (POAG) or chronic angle-closure glaucoma (CACG). DESIGN: Nonrandomized, open-label, prospective, intervention ... Full text Link to item Cite

Square-edge polymethylmethacrylate intraocular lens design for reducing posterior capsule opacification following paediatric cataract surgery: initial experience.

Journal Article Clin Exp Ophthalmol · October 2008 PURPOSE: To compare the incidence and severity of development of posterior capsule opacification (PCO) following implantation of square-edged polymethylmethacrylate (PMMA) or hydrophobic acrylic intraocular lenses (IOLs) following paediatric cataract surge ... Full text Link to item Cite

Pentacam tomograms: a novel method for quantification of posterior capsule opacification.

Journal Article Invest Ophthalmol Vis Sci · May 2008 PURPOSE: To develop and validate a method to quantify posterior capsule opacification (PCO) in eyes after cataract surgery and intraocular lens implantation using Scheimpflug Pentacam tomograms and compare its validity with slit lamp retroillumination imag ... Full text Link to item Cite

Moyamoya vasculopathy in a child after hemolytic uremic syndrome: a possible etiopathogenesis.

Journal Article Neuropediatrics · April 2008 Moyamoya disease is a cerebral vasculopathy of unknown etiology frequently seen in the Asian population. We report a case of moyamoya vasculopathy in an African-American child who had renal failure followed by cerebral ischemia. Our patient presented with ... Full text Link to item Cite

Artificial neural network-based glaucoma diagnosis using retinal nerve fiber layer analysis.

Journal Article Eur J Ophthalmol · 2008 PURPOSE: To develop, train, and test an artificial neural network (ANN) for differentiating among normal subjects, primary open angle glaucoma (POAG) suspects, and persons with POAG in Asian-Indian eyes using inputs from clinical parameters, optical cohere ... Full text Link to item Cite

Posterior capsule rupture following closed globe injury: Scheimpflug imaging, pathogenesis, and management.

Journal Article Eur J Ophthalmol · 2008 PURPOSE: To report the Scheimpflug and clinical findings in a case of pediatric posterior capsule rupture due to blunt ocular trauma. METHODS: Interventional case report. Analysis of Scheimpflug findings and review of literature. RESULTS: An 11-year-old bo ... Full text Link to item Cite

Unilateral electric cataract: Scheimpflug imaging and review of the literature.

Journal Article J Cataract Refract Surg · June 2007 A 22-year-old man presented with diminution of vision in the left eye 1 month after sustaining an injury from a high-voltage electric current to the left side of his head. Slitlamp examination and Scheimpflug imaging confirmed the typical anterior subcapsu ... Full text Link to item Cite

In vivo fluorescein staining of SI-30NB silicone intraocular lens.

Journal Article J Cataract Refract Surg · January 2007 We report a case of a 48-year-old pseudophakic woman who presented 3 weeks after Heidelberg retinal angiography using intravenous sodium fluorescein 2%. Bilateral retinal vasculitis with severe retinal ischemia and extensive capillary dropouts had been dia ... Full text Link to item Cite

Repeatability of corneal parameters with Pentacam after laser in situ keratomileusis.

Journal Article Indian J Ophthalmol · 2007 AIM: To investigate the coefficient of repeatability (CR) for corneal parameters evaluated with Pentacam after laser in situ keratomileusis (LASIK) in myopic eyes. DESIGN AND SETTING: Prospective, non-interventional, non-comparative study in an institution ... Link to item Cite

Scheimpflug imaging in late Capsular Bag Distention syndrome after phacoemulsification.

Journal Article Am J Ophthalmol · December 2006 PURPOSE: To describe two cases of late Capsular Bag Distention syndrome (CBDS) and posterior capsular opacification (PCO) as documented on Pentacam. DESIGN: Case series. METHODS: A 55-year-old male and a 72-year-old female presented three years after phaco ... Full text Link to item Cite

Role of scheimpflug imaging in traumatic intralenticular foreign body.

Journal Article Am J Ophthalmol · October 2006 PURPOSE: The role of Pentacam Scheimpflug imaging in evaluation of penetrating eye injury and intralenticular foreign body (ILFB). DESIGN: Interventional case report. METHODS: A 35-year-old male presented to our clinical practice with penetrating eye injur ... Full text Link to item Cite