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Ilene C. Siegler

Professor in Psychiatry and Behavioral Sciences
Psychiatry & Behavioral Sciences, Behavioral Medicine & Neurosciences
3815 Stoneycreek Road, Chapel Hill, NC 27514
3815 Stoneycreek Road, Chapel Hill, NC 27514

Selected Publications


Predicting physical activity by the personality styles of the five-factor model.

Journal Article Health Psychol · October 2024 OBJECTIVE: Low neuroticism, high extraversion, and high conscientiousness are related to physical activity (PA). We tested whether the small size and heterogeneity of these relationships result because personality traits influence one another as well as be ... Full text Link to item Cite

Genome-Wide Genetic Analysis of Dropout in a Controlled Exercise Intervention in Sedentary Adults With Overweight or Obesity and Cardiometabolic Disease.

Journal Article Ann Behav Med · April 11, 2024 BACKGROUND: Despite the benefits of exercise, many individuals are unable or unwilling to adopt an exercise intervention. PURPOSE: The purpose of this analysis was to identify putative genetic variants associated with dropout from exercise training interve ... Full text Open Access Link to item Cite

Effect of Remotely Supervised Weight Loss and Exercise Training Versus Lifestyle Counseling on Cardiovascular Risk and Clinical Outcomes in Older Adults With Rheumatoid Arthritis: A Randomized Controlled Trial.

Journal Article ACR Open Rheumatol · March 2024 OBJECTIVE: To compare a remotely supervised weight loss and exercise intervention to lifestyle counseling for effects on cardiovascular disease risk, disease activity, and patient-reported outcomes in older patients with rheumatoid arthritis (RA) and overw ... Full text Link to item Cite

Remotely Supervised Weight Loss and Exercise Training to Improve Rheumatoid Arthritis Cardiovascular Risk: Rationale and Design of the Supervised Weight Loss Plus Exercise Training-Rheumatoid Arthritis Trial.

Journal Article ACR Open Rheumatol · May 2023 Patients with rheumatoid arthritis (RA) remain at an increased risk for cardiovascular disease (CVD) and mortality. RA CVD results from a combination of traditional risk factors and RA-related systemic inflammation. One hypothetical means of improving over ... Full text Open Access Link to item Cite

Demographic, Clinical, and Psychosocial Predictors of Exercise Adherence: The STRRIDE Trials.

Journal Article Transl J Am Coll Sports Med · 2023 PURPOSE: To identify baseline demographic, clinical, and psychosocial predictors of exercise intervention adherence in the Studies of a Targeted Risk Reduction Intervention through Defined Exercise (STRRIDE) trials. METHODS: A total of 947 adults with dysl ... Full text Open Access Link to item Cite

Race and sex differences in dropout from the STRRIDE trials.

Journal Article Front Sports Act Living · 2023 PURPOSE: To determine if race and sex differences exist in determinants and timing of dropout among individuals enrolled in an exercise and/or caloric restriction intervention. METHODS: A total of 947 adults with dyslipidemia (STRRIDE I, STRRIDE AT/RT) or ... Full text Open Access Link to item Cite

Amount and intensity effects of exercise training alone versus a combined diet and exercise lifestyle intervention on health-related quality of life in the STRRIDE-PD randomized trial.

Journal Article BMJ Open Diabetes Res Care · January 2022 INTRODUCTION: To determine the relative contributions of various amounts and intensities of exercise alone to a combined lifestyle intervention on health-related quality of life (HrQoL) measures. RESEARCH DESIGN AND METHODS: Participants (n=162) were seden ... Full text Link to item Cite

Determinants of Dropout from and Variation in Adherence to an Exercise Intervention: The STRRIDE Randomized Trials.

Journal Article Transl J Am Coll Sports Med · 2022 PURPOSE: This study aimed to characterize the timing and self-reported determinants of exercise dropout among sedentary adults with overweight or obesity. We also sought to explore variations in adherence among individuals who completed a 6- to 8-month str ... Full text Open Access Link to item Cite

Sex and race differences of cerebrospinal fluid metabolites in healthy individuals.

Journal Article Metabolomics · January 18, 2021 INTRODUCTION: Analyses of cerebrospinal fluid (CSF) metabolites in large, healthy samples have been limited and potential demographic moderators of brain metabolism are largely unknown. OBJECTIVE: Our objective in this study was to examine sex and race dif ... Full text Link to item Cite

Correction to: Low Life Course Socioeconomic Status (SES) Is Associated with Negative NEO PI-R Personality Patterns.

Journal Article Int J Behav Med · December 2020 After the publication of the original article, the Editor was notified by Duke University that they have determined the authorship to be incomplete. Consequently, Dr Edward Suarez has been added as a co-author to represent his contribution to the conceptio ... Full text Link to item Cite

Evaluating the precision of EBF1 SNP x stress interaction association: sex, race, and age differences in a big harmonized data set of 28,026 participants.

Journal Article Transl Psychiatry · October 20, 2020 In prior work, we identified a novel gene-by-stress association of EBF1's common variation (SNP rs4704963) with obesity (i.e., hip, waist) in Whites, which was further strengthened through multiple replications using our synthetic stress measure. We now ex ... Full text Open Access Link to item Cite

Associations of self-reported eating disorder behaviors and personality in a college-educated sample.

Journal Article Appetite · August 1, 2020 OBJECTIVE: In order to better understand factors motivating eating disorder (ED) behaviors and better identify persons at-risk for these behaviors, we sought to identify which personality domains and facets were associated with behaviors for weight control ... Full text Link to item Cite

Systolic Blood Pressure and Socioeconomic Status in a large multi-study population.

Journal Article SSM Popul Health · December 2019 The present study used harmonized data from eight studies (N = 28,891) to examine the association between socioeconomic status (SES) and resting systolic blood pressure (SBP). The study replicates and extends our prior work on this topic by examining poten ... Full text Open Access Link to item Cite

Epigenome-Wide Association Study for All-Cause Mortality in a Cardiovascular Cohort Identifies Differential Methylation in Castor Zinc Finger 1 (CASZ1).

Journal Article J Am Heart Assoc · November 5, 2019 Background DNA methylation is implicated in many chronic diseases and may contribute to mortality. Therefore, we conducted an epigenome-wide association study (EWAS) for all-cause mortality with whole-transcriptome data in a cardiovascular cohort (CATHGEN ... Full text Link to item Cite

Lifecourse perspective and health

Chapter · June 5, 2019 Cite

The Effects of Tryptophan Enhancement and Depletion on Plasma Catecholamine Levels in Healthy Individuals.

Journal Article Psychosom Med · January 2019 OBJECTIVE: Central nervous system (CNS) serotonin (5-HT) exerts both excitatory and inhibitory effects on the sympathetic nervous system (SNS) in animals. In this study, we examine the effects of tryptophan enhancement and depletion on plasma catecholamine ... Full text Link to item Cite

The role of genetic and environmental influences on the association between childhood ADHD symptoms and BMI.

Journal Article Int J Obes (Lond) · January 2019 BACKGROUND/OBJECTIVES: Although childhood attention deficit hyperactivity disorder (ADHD) has been previously associated with concurrent and later obesity in adulthood, the etiology of this association remains unclear. The objective of this study is to det ... Full text Link to item Cite

Developing a synthetic psychosocial stress measure and harmonizing CVD-risk data: a way forward to GxE meta- and mega-analyses.

Journal Article BMC Res Notes · July 24, 2018 OBJECTIVES: Among many challenges in cardiovascular disease (CVD) risk prediction are interactions of genes with stress, race, and/or sex and developing robust estimates of these interactions. Improved power with larger sample size contributed by the accum ... Full text Link to item Cite

Genetic Variation in Acid Ceramidase Predicts Non-completion of an Exercise Intervention.

Journal Article Front Physiol · 2018 Genetic variation is associated with a number of lifestyle behaviours; it may be associated with adherence and individual responses to exercise training. We tested single nucleotide polymorphisms (SNPs) in the acid ceramidase gene (ASAH1) for association w ... Full text Link to item Cite

Lack of Association of a Functional Polymorphism in the Serotonin Receptor Gene With Body Mass Index and Depressive Symptoms in a Large Meta-Analysis of Population Based Studies.

Journal Article Front Genet · 2018 The serotonin receptor 5-HTR2C is thought to be involved in the function of multiple brain structures. Consequently, the HTR2C gene has been studied extensively with respect to its association with a variety of phenotypes. One coding variant in the HTR2C g ... Full text Open Access Link to item Cite

Neuroticism Increases PTSD Symptom Severity by Amplifying the Emotionality, Rehearsal, and Centrality of Trauma Memories.

Journal Article J Pers · October 2017 OBJECTIVE: Although it is well established that neuroticism increases the risk of posttraumatic stress disorder (PTSD), little is known about the mechanisms that promote PTSD in individuals with elevated levels of neuroticism. Across two studies, we examin ... Full text Open Access Link to item Cite

Brain-derived neurotrophic factor rs6265 (Val66Met) polymorphism is associated with disease severity and incidence of cardiovascular events in a patient cohort.

Journal Article Am Heart J · August 2017 BACKGROUND: The rs6265 (Val66Met) single-nucleotide polymorphism in the BDNF gene has been related to a number of endophenotypes that have in turn been shown to confer risk for atherosclerotic cardiovascular disease (CVD). To date, however, very few studie ... Full text Link to item Cite

Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism interacts with gender to influence cortisol responses to mental stress.

Journal Article Psychoneuroendocrinology · May 2017 Brain-derived neurotrophic factor (BDNF) Val66Met polymorphism has been associated with cortisol responses to stress with gender differences reported, although the findings are not entirely consistent. To evaluate the role of Val66Met genotype and gender o ... Full text Link to item Cite

Population differences in associations of serotonin transporter promoter polymorphism (5HTTLPR) di- and triallelic genotypes with blood pressure and hypertension prevalence.

Journal Article Am Heart J · March 2017 UNLABELLED: Based on prior research finding the 5HTTLPR L allele associated with increased cardiovascular reactivity to laboratory stressors and increased risk of myocardial infarction, we hypothesized that the 5HTTLPR L allele will be associated with incr ... Full text Link to item Cite

Personality Traits and Successful Aging: Findings From the Georgia Centenarian Study.

Journal Article Int J Aging Hum Dev · September 2016 The current study attempted to describe how personality traits of older adults are associated with components of successful aging (cognition, volunteering, activities of daily living, and subjective health). Three-hundred and six octogenarians and centenar ... Full text Link to item Cite

Maladaptive trauma appraisals mediate the relation between attachment anxiety and PTSD symptom severity.

Journal Article Psychol Trauma · May 2016 OBJECTIVE: In a large sample of community-dwelling older adults with histories of exposure to a broad range of traumatic events, we examined the extent to which appraisals of traumatic events mediate the relations between insecure attachment styles and pos ... Full text Open Access Link to item Cite

Accounting for Posttraumatic Stress Disorder Symptom Severity With Pre- and Posttrauma Measures: A Longitudinal Study of Older Adults.

Journal Article Clin Psychol Sci · March 2016 Using data from a longitudinal study of community-dwelling older adults, we analyzed the most extensive set of known correlates of PTSD symptoms obtained from a single sample to examine the measures' independent and combined utility in accounting for PTSD ... Full text Open Access Link to item Cite

Depression, Stressful Life Events, and the Impact of Variation in the Serotonin Transporter: Findings from the National Longitudinal Study of Adolescent to Adult Health (Add Health).

Journal Article PLoS One · 2016 BACKGROUND: The low transcriptionally efficient short-allele of the 5HTTLPR serotonin transporter polymorphism has been implicated to moderate the relationship between the experience of stressful life events (SLEs) and depression. Despite numerous attempts ... Full text Link to item Cite

Capability for suicide interacts with states of heightened arousal to predict death by suicide beyond the effects of depression and hopelessness.

Journal Article J Affect Disord · December 1, 2015 BACKGROUND: States of heightened arousal (e.g., agitation, sleep disturbance) have been repeatedly linked to suicidal thoughts and behaviors, including attempts and death. Studies have further indicated that these states may be particularly pernicious amon ... Full text Link to item Cite

Computing a Synthetic Chronic Psychosocial Stress Measurement in Multiple Datasets and its Application in the Replication of G × E Interactions of the EBF1 Gene.

Journal Article Genet Epidemiol · September 2015 Chronic psychosocial stress adversely affects health and is associated with the development of disease [Williams, 2008]. Systematic epidemiological and genetic studies are needed to uncover genetic variants that interact with stress to modify metabolic res ... Full text Link to item Cite

The relation between insecure attachment and posttraumatic stress: Early life versus adulthood traumas.

Journal Article Psychol Trauma · July 2015 The present study examined the relations between insecure attachment and posttraumatic stress disorder (PTSD) symptoms among community-dwelling older adults with exposure to a broad range of traumatic events. Attachment anxiety and attachment avoidance pre ... Full text Open Access Link to item Cite

Gene by stress genome-wide interaction analysis and path analysis identify EBF1 as a cardiovascular and metabolic risk gene.

Journal Article Eur J Hum Genet · June 2015 We performed gene-environment interaction genome-wide association analysis (G × E GWAS) to identify SNPs whose effects on metabolic traits are modified by chronic psychosocial stress in the Multi-Ethnic Study of Atherosclerosis (MESA). In Whites, the G × E ... Full text Open Access Link to item Cite

Population frequencies of the Triallelic 5HTTLPR in six Ethnicially diverse samples from North America, Southeast Asia, and Africa.

Journal Article Behav Genet · March 2015 Genetic differences between populations are potentially an important contributor to health disparities around the globe. As differences in gene frequencies influence study design, it is important to have a thorough understanding of the natural variation of ... Full text Link to item Cite

Associations between central nervous system serotonin, fasting glucose, and hostility in African American females.

Journal Article Ann Behav Med · February 2015 BACKGROUND: Previous research has shown an association between hostility and fasting glucose in African American women. Central nervous system serotonin activity is implicated both in metabolic processes and in hostility related traits. PURPOSE: The purpos ... Full text Link to item Cite

Successful aging and subjective well-being among oldest-old adults.

Journal Article Gerontologist · February 2015 PURPOSE OF THE STUDY: This research integrates successful aging and developmental adaptation models to empirically define the direct and indirect effects of 2 distal (i.e., education and past life experiences) and 5 proximal influences (i.e., physical func ... Full text Link to item Cite

Personality Structure Among Centenarians: The Georgia Centenarian Study.

Journal Article Exp Aging Res · 2015 UNLABELLED: BACKGROUND/STUDY CONTEXT: We demonstrate that observer-rated factor structure of personality in centenarians is congruent with the normative structure. Prevalence of cognitive impairment, which has previously been linked to changes in personali ... Full text Link to item Cite

Octogenarian and centenarian performance on the Fuld Object Memory Evaluation.

Journal Article Neuropsychol Dev Cogn B Aging Neuropsychol Cogn · 2015 The Fuld Object Memory Evaluation (FOME) has considerable utility for cognitive assessment in older adults, but there are few normative data, particularly for the oldest old. In this study, 80 octogenarians and 244 centenarians from the Georgia Centenarian ... Full text Link to item Cite

A functional polymorphism in the HTR2C gene associated with stress responses: a validation study.

Journal Article Biol Psychol · December 2014 Previously we have shown that a functional nonsynonymous single nucleotide polymorphism (SNP), rs6318 on the HTR2C gene located on the X-chromosome, is associated with hypothalamic-pituitary-adrenal axis response to a laboratory stress recall task. The pre ... Full text Link to item Cite

Personality facets and all-cause mortality among Medicare patients aged 66 to 102 years: a follow-on study of Weiss and Costa (2005).

Journal Article Psychosom Med · June 2014 OBJECTIVE: To investigate associations between personality facets and survival during an 8-year follow-up. METHODS: In 597 Medicare recipients (age, 66-102 years) followed up for approximately 8 years, personality domains and facets were assessed using the ... Full text Link to item Cite

Changes in neuroticism following trauma exposure.

Journal Article J Pers · April 2014 Using longitudinal data, the present study examined change in midlife neuroticism following trauma exposure. Our primary analyses included 670 participants (M(age) = 60.55; 65.22% male, 99.70% Caucasian) who completed the NEO Personality Inventory at ages ... Full text Open Access Link to item Cite

APOE ϵ4, rated life experiences, and affect among centenarians.

Journal Article Aging Ment Health · March 2014 OBJECTIVES: The purpose of this study was to assess the relationship between apolipoprotein E (APOE), life events and engagement, and subjective well-being (as measured by positive and negative affect) among centenarians. Based on the life stress paradigm, ... Full text Link to item Cite

A putatively functional polymorphism in the HTR2C gene is associated with depressive symptoms in white females reporting significant life stress.

Journal Article PLoS One · 2014 Psychosocial stress is well known to be positively associated with subsequent depressive symptoms. Cortisol response to stress may be one of a number of biological mechanisms that links psychological stress to depressive symptoms, although the precise caus ... Full text Open Access Link to item Cite

MAOA genotype, childhood maltreatment, and their interaction in the etiology of adult antisocial behaviors.

Journal Article Biol Psychiatry · January 1, 2014 BACKGROUND: Maltreatment by an adult or caregiver during childhood is a prevalent and important predictor of antisocial behaviors in adulthood. A functional promoter polymorphism in the monoamine oxidase A (MAOA) gene has been implicated as a moderating fa ... Full text Link to item Cite

Cumulative exposure to traumatic events in older adults.

Journal Article Aging Ment Health · 2014 OBJECTIVES: The present study examined the impact of cumulative trauma exposure on current posttraumatic stress disorder (PTSD) symptom severity in a nonclinical sample of adults in their 60s. The predictive utility of cumulative trauma exposure was compar ... Full text Open Access Link to item Cite

The impact of the developmental timing of trauma exposure on PTSD symptoms and psychosocial functioning among older adults.

Journal Article Dev Psychol · November 2013 The present study examined the impact of the developmental timing of trauma exposure on posttraumatic stress disorder (PTSD) symptoms and psychosocial functioning in a large sample of community-dwelling older adults (N = 1,995). Specifically, we investigat ... Full text Open Access Link to item Cite

The Frequency and Impact of Exposure to Potentially Traumatic Events Over the Life Course.

Journal Article Clin Psychol Sci · October 1, 2013 We examined the frequency and impact of exposure to potentially traumatic events among a nonclinical sample of older adults (n = 3,575), a population typically underrepresented in epidemiological research concerning the prevalence of traumatic events. Curr ... Full text Open Access Link to item Cite

Social, behavioral, and genetic linkages from adolescence into adulthood.

Journal Article Am J Public Health · October 2013 The influence of genetic factors on health and behavior is conditioned by social, cultural, institutional, and physical environments in which individuals live, work, and play. We encourage studies supporting multilevel integrative approaches to understandi ... Full text Link to item Cite

Consistency and timing of marital transitions and survival during midlife: the role of personality and health risk behaviors.

Journal Article Ann Behav Med · June 2013 BACKGROUND: Marital status is associated with survival. PURPOSE: The aims of this study are to evaluate marital history and timing on mortality during midlife, test the role of pre-marital personality, and quantify the role of health risk behaviors. METHOD ... Full text Link to item Cite

Chronic family stress moderates the association between a TOMM40 variant and triglyceride levels in two independent Caucasian samples.

Journal Article Biol Psychol · April 2013 TOMM40 SNP rs157580 has been associated with triglyceride levels in genome-wide association studies (GWAS). Chronic caregiving stress moderates the association between triglyceride levels and a nearby SNP rs439401 that is associated with triglyceride level ... Full text Link to item Cite

Correlates of functional capacity among centenarians.

Journal Article J Appl Gerontol · April 2013 This study investigated correlates of functional capacity among participants of the Georgia Centenarian Study. Six domains (demographics and health, positive and negative affect, personality, social and economic support, life events and coping, distal infl ... Full text Link to item Cite

Brain-derived neurotrophic factor (BDNF) Val66Met and adulthood chronic stress interact to affect depressive symptoms.

Journal Article J Psychiatr Res · February 2013 BACKGROUND: BDNF Val66Met by chronic stress interaction has been studied using childhood stress as a moderator, but has not been widely studied using chronic stress in adulthood. METHODS: Two independent samples were used: Duke-CG (238 Caucasians) and MESA ... Full text Link to item Cite

A functional polymorphism in the 5HTR2C gene associated with stress responses also predicts incident cardiovascular events.

Journal Article PLoS One · 2013 Previously we have shown that a functional nonsynonymous single nucleotide polymorphism (rs6318) of the 5HTR2C gene located on the X-chromosome is associated with hypothalamic-pituitary-adrenal axis response to a stress recall task, and with endophenotypes ... Full text Open Access Link to item Cite

Long-Term Impact of Caregiving and Metabolic Syndrome with Perceived Decline in Cognitive Function 8 Years Later: A Pilot Study Suggesting Important Avenues for Future Research.

Journal Article Open J Med Psychol · January 2013 The chronic stress of caregiving has been associated with increased risk for cognitive decline and dementia. One theoretical model suggests that a group of risk factors known as the metabolic syndrome MET_SYN (e.g. hypertension, poor glucose regulation, ce ... Full text Link to item Cite

Socioeconomic indices as independent correlates of C-reactive protein in the National Longitudinal Study of Adolescent Health.

Journal Article Psychosom Med · 2013 OBJECTIVES: To examine the association between socioeconomic status (SES) and C-reactive protein (CRP) to understand how SES may increase the risk of cardiovascular disease and thus identify targets for prevention measures. METHODS: Path models were used t ... Full text Link to item Cite

The serotonin transporter gene polymorphism (5HTTLPR) moderates the effect of adolescent environmental conditions on self-esteem in young adulthood: a structural equation modeling approach.

Journal Article Biol Psychol · September 2012 Here we examine the effects of both self-reported and independent observer-reported environmental risk indices, the serotonin transporter gene promoter (5HTTLPR) polymorphism, and their interaction on self-esteem. This trait was assessed during early and m ... Full text Open Access Link to item Cite

Parenting styles and body mass index trajectories from adolescence to adulthood.

Journal Article Health Psychol · July 2012 OBJECTIVE: Parenting styles such as authoritarian, disengaged, or permissive are thought to be associated with greater adolescent obesity risk than an authoritative style. This study assessed the relationship between parenting styles and changes in body ma ... Full text Link to item Cite

Associations of Social Support and 8-Year Follow-Up Depressive Symptoms: Differences in African American and White Caregivers.

Journal Article Clin Gerontol · June 1, 2012 The present study used data from the Alzheimer's Study of Emotions in Caregivers (ASEC) to evaluate perceptions of social support assessed at baseline, as well as changes in social support assessed at a follow-up eight-years later, as predictors of symptom ... Full text Link to item Cite

Understanding dementia prevalence among centenarians.

Journal Article J Gerontol A Biol Sci Med Sci · April 2012 The goals of this article are to (a) establish the concurrent and clinical validity of the Global Deterioration scale in assessing cognitive functions and stages of dementia among centenarians, (b) identify the prevalence of all-cause dementia in represent ... Full text Link to item Cite

Diabetes mellitus in centenarians.

Journal Article J Am Geriatr Soc · March 2012 OBJECTIVES: To describe the prevalence of diabetes mellitus (DM) in centenarians. DESIGN: Cross-sectional, population-based. SETTING: Forty-four counties in northern Georgia. PARTICIPANTS: Two hundred forty-four centenarians (aged 98-108, 15.8% male, 20.5% ... Full text Link to item Cite

Systolic blood pressure and adiposity: examination by race and gender in a nationally representative sample of young adults.

Journal Article Am J Hypertens · February 2012 BACKGROUND: Adiposity, or more specifically, underlying body fat distribution, has been associated with systolic blood pressure (SBP), and it has been suggested that these associations vary between whites and blacks, as well as by gender. METHODS: Here, we ... Full text Link to item Cite

Cortisol responses to emotional stress in men: association with a functional polymorphism in the 5HTR2C gene.

Journal Article Biol Psychol · January 2012 The serotonin 5HTR2C receptor has been shown to mediate HPA axis activation during stress. We hypothesized that a functional polymorphism (rs6318) of the 5HTR2C gene would be associated with HPA axis response to a laboratory stress protocol. The present sa ... Full text Link to item Cite

Life events and personality predicting loneliness among centenarians: findings from the Georgia Centenarian Study.

Journal Article J Psychol · 2012 Regarding the purpose of this study, the researchers analyzed the roles that both life events (life-time positive events and life-time negative events) and personality (Neuroticism, Extraversion, Trust, Competence, and Ideas) played in participants of the ... Full text Link to item Cite

Two versions of life: emotionally negative and positive life events have different roles in the organization of life story and identity.

Journal Article Emotion · October 2011 Over 2,000 adults in their sixties completed the Centrality of Event Scale (CES) for the traumatic or negative event that now troubled them the most and for their most positive life event, as well as measures of current PTSD symptoms, depression, well-bein ... Full text Open Access Link to item Cite

Systolic blood pressure, socioeconomic status, and biobehavioral risk factors in a nationally representative US young adult sample.

Journal Article Hypertension · August 2011 In the National Longitudinal Study of Adolescent Health, a US longitudinal study of >15 000 young adults, we examined the extent to which socioeconomic status is linked to systolic blood pressure (SBP) and whether biobehavioral risk factors mediate the ass ... Full text Link to item Cite

Recovery expectations and long-term prognosis of patients with coronary heart disease.

Journal Article Arch Intern Med · May 23, 2011 BACKGROUND: Expectations of patients regarding their prospects for recovery have been shown to predict subsequent physical and social functioning. Evidence regarding the impact of expectations on clinical outcomes is limited. METHODS: At the inpatient serv ... Full text Link to item Cite

Effects of 5HTTLPR on cardiovascular response to an emotional stressor.

Journal Article Psychosom Med · May 2011 OBJECTIVES: To replicate a prior main effect of the serotonin transporter gene promoter (5HTTLPR) genotype on cardiovascular reactivity (CVR) and explore caregiver stress as a potential moderator of 5HTTLPR effects on CVR. On the basis of prior findings, w ... Full text Link to item Cite

Affect and loneliness among centenarians and the oldest old: the role of individual and social resources.

Journal Article Aging Ment Health · April 2011 OBJECTIVES: Affect and loneliness are important indicators of mental health and well-being in older adulthood and are linked to significant outcomes including physical health and mortality. Given a large focus on young-old adults within gerontological rese ... Full text Link to item Cite

Low life course socioeconomic status (SES) is associated with negative NEO PI-R personality patterns.

Journal Article Int J Behav Med · March 2011 BACKGROUND: Low socioeconomic status (SES) is associated with poor health. One potential pathway accounting for this relationship may be an association between low SES and personality characteristics that affect health. METHODS: Associations among parent's ... Full text Link to item Cite

Associations between APOE variants and metabolic traits and the impact of psychological stress.

Journal Article PLoS One · January 19, 2011 OBJECTIVE: In a previous study, we observed that associations between APOE rs439401 and metabolic traits were moderated by chronic stress. Thus, in a population of stressed and non-stressed Danish men, we examined whether associations between APOE rs439401 ... Full text Link to item Cite

Cognitive function, physical performance, health, and disease: norms from the georgia centenarian study.

Journal Article Exp Aging Res · October 2010 This study provides, for the first time, normative data on cognitive functioning and physical performance, health and health behaviors, and diseases from a population-based sample of 244 centenarians and near-centenarians (M age = 100.5 years, range 98-108 ... Full text Link to item Cite

Central nervous system serotonin and clustering of hostility, psychosocial, metabolic, and cardiovascular endophenotypes in men.

Journal Article Psychosom Med · September 2010 OBJECTIVE: To use measures of cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5HIAA) and genotype of a functional polymorphism of the monoamine oxidase A gene promoter (MAOA-uVNTR) to study the role of central nervous system (CNS) serotonin in cluste ... Full text Link to item Cite

Caregiving, residence, race, and depressive symptoms.

Journal Article Aging Ment Health · September 2010 The objective of this study is to evaluate the psychological responses to caregiving between black and white dementia caregivers measured by self-reports of depressive symptoms evaluating the impact of sub-components of the Center for Epidemiologic Studies ... Full text Link to item Cite

Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls.

Journal Article Psychosom Med · June 2010 OBJECTIVE: To examine the association between apolipoprotein E (APOE) gene variants and waist circumference, fasting plasma glucose, serum insulin, serum high-density lipoprotein cholesterol, and serum triglycerides, all metabolic traits known as cardiovas ... Full text Link to item Cite

Associations of depressive symptoms, trait hostility, and gender with C-reactive protein and interleukin-6 response after emotion recall.

Journal Article Psychosom Med · May 2010 OBJECTIVE: To examine the effects of depressive symptoms and hostility on changes in C-reactive protein (CRP) and interleukin (IL)-6 in response to an acute laboratory stressor. Depressive symptoms moderate the effect of trait hostility on circulating leve ... Full text Link to item Cite

Socioeconomic status moderates associations between CNS serotonin and expression of beta2-integrins CD11b and CD11c.

Journal Article J Psychiatr Res · April 2010 One of the first steps in the development of atherogenesis is adhesion of circulating monocytes to the vascular endothelium that is stimulated by beta(2)-integrins. Stress has been associated with enhanced expression of beta(2)-integrins on monocyte cell s ... Full text Link to item Cite

Personality and inflammation: the protective effect of openness to experience.

Journal Article Ethn Dis · 2010 BACKGROUND: Prior research found reduced mortality in coronary heart patients with higher scores on the Openness to Experience domain and its facets. Decreased C-reactive protein level (CRP) levels may be one mechanism by which higher Openness to Experienc ... Link to item Cite

Predicting successful aging in a population-based sample of georgia centenarians.

Journal Article Curr Gerontol Geriatr Res · 2010 Used a population-based sample (Georgia Centenarian Study, GCS), to determine proportions of centenarians reaching 100 years as (1) survivors (43%) of chronic diseases first experienced between 0-80 years of age, (2) delayers (36%) with chronic diseases fi ... Full text Link to item Cite

Personality: Life span compass for health

Journal Article Annual Review of Gerontology and Geriatrics · January 1, 2010 Personality is crucial for understanding health in later life. Yet classic conceptions of personality with emphasis on stability may have limited the empirical attention it deserved in relation to health. This chapter highlights the six foci of a personali ... Full text Cite

Depression among centenarians and the oldest old: contributions of cognition and personality.

Journal Article Gerontology · 2010 BACKGROUND: An estimated 20% of adults over the age of 55 experience clinical mental disorders such as depression and anxiety. For older adults, mental health concerns are often undetected, concomitant with physical challenges, and ultimately go untreated. ... Full text Link to item Cite

Engaged Lifestyle, Personality, and Mental Status Among Centenarians.

Journal Article J Adult Dev · December 2009 This study assessed engaged lifestyle activities (e.g., volunteering, traveling, and public speaking) for centenarians of the Georgia Centenarian Study. A total of 285 centenarians and near-centenarians (i.e., 98 years and older) and their proxy informants ... Full text Link to item Cite

Positive affect is associated with cardiovascular reactivity, norepinephrine level, and morning rise in salivary cortisol.

Journal Article Psychophysiology · July 2009 Positive affect was examined as a predictor of (1) cardiovascular reactivity during a sadness and an anger recall task and recovery following the protocol, (2) epinephrine (EPI) and norepinephrine (NOREPI) reactivity and level during the recall protocol, a ... Full text Link to item Cite

Hostility and fasting glucose in African American women.

Journal Article Psychosom Med · July 2009 OBJECTIVE: To examine whether the relationship of hostility (HOST) to fasting glucose indices is moderated by sex and race. HOST has been associated with abnormalities in glucose metabolism. Prior studies suggested that this association may be more prevale ... Full text Link to item Cite

HPA axis function in male caregivers: effect of the monoamine oxidase-A gene promoter (MAOA-uVNTR).

Journal Article Biol Psychol · October 2008 Caregiving stress is associated with negative health outcomes. Neuroendocrine functioning may be a mediator of such outcomes. The MAOA gene regulates activity of neurotransmitters involved with neuroendocrine responses to stress. Differences in polymorphis ... Full text Link to item Cite

5-HTTLPR and gender moderate changes in negative affect responses to tryptophan infusion.

Journal Article Behav Genet · September 2008 Expression of the serotonin transporter is affected by the genotype of the 5-HTTLPR (short and long forms) as well as the genotype of the SNP rs25531 within this region. Based on the combined genotypes for these polymorphisms, we designated each allele as ... Full text Link to item Cite

Associations among central nervous system serotonergic function and neuroticism are moderated by gender.

Journal Article Biol Psychol · May 2008 Serotonergic dysregulation is associated with negative affect. Plasma prolactin responses to a tryptophan enhancement challenge are used as a measure of central nervous system serotonergic activity. We examined prolactin responses to a tryptophan challenge ... Full text Link to item Cite

Lipid levels are associated with a regulatory polymorphism of the monoamine oxidase-A gene promoter (MAOA-uVNTR).

Journal Article Med Sci Monit · February 2008 BACKGROUND: The monoamine oxidase-A (MAOA) gene plays a vital role in the metabolism of neurotransmitters, e.g, serotonin, norepinephrine, and dopamine. A polymorphism in the promoter region (MAOA-uVNTR) affects transcriptional efficiency. Allelic variatio ... Link to item Cite

Childhood socioeconomic status and serotonin transporter gene polymorphism enhance cardiovascular reactivity to mental stress.

Journal Article Psychosom Med · January 2008 OBJECTIVE: To test the hypothesis that low socioeconomic status (SES) and the 5HTTLPR L allele are associated with increased cardiovascular reactivity (CVR) to stress in a larger sample and that SES and 5HTTLPR genotypes interact to enhance CVR to stress. ... Full text Link to item Cite

Effects of environmental stress and gender on associations among symptoms of depression and the serotonin transporter gene linked polymorphic region (5-HTTLPR).

Journal Article Behav Genet · January 2008 The short (s) variant of the serotonin transporter (5-HTT) gene linked functional polymorphic region (5-HTTLPR) is associated with depression. Stressful life events, gender, and race have been shown to moderate this association. We examined the relationshi ... Full text Link to item Cite

Personality as a predictor of dietary quality in spouses during midlife.

Journal Article Behav Med · 2008 The authors evaluated the NEO Personality Inventory-Revised (NEO-PI-R) as a predictor of dietary quality in 850 married couples, focusing on associations among each participant's personality as a predictor of their own dietary quality and their spouses' di ... Full text Link to item Cite

Discrimination, dispositions, and cardiovascular responses to stress.

Journal Article Health Psychol · November 2007 OBJECTIVE: Recent research suggests that past exposure to discrimination may influence perceptions of, and physiological responses to, new challenges. The authors examined how race and trait levels of hostility and optimism interact with past exposure to d ... Full text Link to item Cite

Associations of a regulatory polymorphism of monoamine oxidase-A gene promoter (MAOA-uVNTR) with symptoms of depression and sleep quality.

Journal Article Psychosom Med · June 2007 OBJECTIVE: To examine the relationships among the variable number of tandem repeats in the monoamine oxidase-A linked polymorphic region allelic variation (MAOA-uVNTR) and the symptoms of depression and sleep quality. The monoamine oxidase-A (MAOA) gene, w ... Full text Link to item Cite

Facets of openness predict mortality in patients with cardiac disease.

Journal Article Psychosom Med · May 2007 OBJECTIVE: To examine the NEO Personality Inventory (NEO PI) Openness to Experience (O) domain and its facets as predictors of cardiac deaths and all-cause mortality. METHODS: The NEO PI was administered to a sample of 977 coronary catheterization patients ... Full text Link to item Cite

Sleep quality varies as a function of 5-HTTLPR genotype and stress.

Journal Article Psychosom Med · 2007 OBJECTIVE: To test the hypothesis that allelic variation in 5HTT gene-linked polymorphic region (5-HTTLPR) genotype was associated with sleep quality (Pittsburgh Sleep Quality Index, PSQI) as a main effect and as moderated by the chronic stress of caregivi ... Full text Link to item Cite

Prediction of all-cause mortality by the Minnesota Multiphasic Personality Inventory Optimism-Pessimism Scale scores: study of a college sample during a 40-year follow-up period.

Journal Article Mayo Clin Proc · December 2006 OBJECTIVE: To examine a measure of explanatory style, the Optimism-Pessimism (PSM) scale derived from college-entry Minnesota Multiphasic Personality Inventory scores, as a predictor of all-cause mortality. SUBJECTS AND METHODS: A total of 7007 students en ... Full text Link to item Cite

Personality and longevity: findings from the Georgia Centenarian Study.

Journal Article Age (Dordr) · December 2006 Centenarians are thought of as unique and exceptional survivors. This study evaluated specific personality traits and configurations of traits among participants of the Georgia Centenarian Study. Two hundred and eighty five centenarians and their nominated ... Full text Link to item Cite

Dietary differences between centenarians residing in communities and in skilled nursing facilities: The Georgia centenarian study

Journal Article Age · December 1, 2006 The purpose of this study was to examine the dietary habits among centenarians residing in community settings (n=105) and in skilled nursing facilities (n=139). The sample was a population-based multi-ethnic sample of adults aged 98 years and older (N=244) ... Full text Cite

Prospective associations between sedentary lifestyle and BMI in midlife.

Journal Article Obesity (Silver Spring) · August 2006 OBJECTIVE: A strong positive cross-sectional relationship between BMI and a sedentary lifestyle has been consistently observed in numerous studies. However, it has been questioned whether high BMI is a determinant or a consequence of a sedentary lifestyle. ... Full text Link to item Cite

NEO personality domains and gender predict levels and trends in body mass index over 14 years during midlife

Journal Article Journal of Research in Personality · June 1, 2006 Mixed models were used to examine NEO-PI scores as predictors of body mass index (BMI) over a 14 year period during midlife. Average BMI levels during midlife were positively related to Neuroticism and negatively related to Openness, Agreeableness, and Con ... Full text Cite

Associations among perceptions of social support, negative affect, and quality of sleep in caregivers and noncaregivers.

Journal Article Health Psychol · March 2006 The authors used structural equation modeling to examine associations among perceptions of negative affect, social support, and quality of sleep in a sample of caregivers (n = 175) and noncaregiver control participants (n = 169). The authors hypothesized t ... Full text Link to item Cite

Effect of race on cultural justifications for caregiving.

Journal Article J Gerontol B Psychol Sci Soc Sci · September 2005 OBJECTIVE: Our objective in this study was to explore the effects of caregiver characteristics on cultural reasons given for providing care to dependent elderly family members. METHODS: The sample included 48 African American and 121 White caregivers. Usin ... Full text Link to item Cite

Psychophysiological mediators of caregiver stress and differential cognitive decline.

Journal Article Psychol Aging · September 2005 The authors examined relationships between chronic stress and cognitive decline and whether such relationships were mediated by psychophysiological factors. Ninety-six caregivers of spouses with Alzheimer's disease (AD) were compared with 95 similar noncar ... Full text Link to item Cite

Hostility, age, and mortality in a sample of cardiac patients.

Journal Article Am J Cardiol · July 1, 2005 This study examined hostility as a predictor of survival in a sample of 1,328 patients who had documented coronary artery disease. After controlling for disease severity, there was a significant interaction between age and hostility. Hostility was signific ... Full text Link to item Cite

Ratings of positive and depressive emotion as predictors of mortality in coronary patients.

Journal Article Int J Cardiol · April 20, 2005 BACKGROUND: An extensive body of research has demonstrated an association between negative affective states and health outcomes. Positive emotions may also influence physical health, however, their examination has received far less attention. METHODS: Posi ... Full text Link to item Cite

Does personality at college entry predict number of reported pain conditions at mid-life? A longitudinal study.

Journal Article J Pain · February 2005 UNLABELLED: The purpose of this study was to evaluate whether personality traits, as assessed by the Minnesota Multiphasic Personality Inventory (MMPI), at time of college entry can predict the number of reported pain conditions at an approximate 30-year f ... Full text Link to item Cite

Initiation and discontinuation of hormone therapy for menopausal symptoms: results from a community sample.

Journal Article J Behav Med · February 2005 Factors related to initiation and discontinuation of hormonal therapy (HT) for treatment of menopausal symptoms were examined in a community sample of 533 peri/postmenopausal women aged 45-54 by telephone three times. Over 40 variables including: sociodemo ... Full text Link to item Cite

Perceived social support as a predictor of mortality in coronary patients: effects of smoking, sedentary behavior, and depressive symptoms.

Journal Article Psychosom Med · 2005 OBJECTIVE: Numerous studies have shown network assessments of social contact predict mortality in patients with coronary artery disease (CAD). Fewer studies have demonstrated an association between perceived social support and longevity in patient samples. ... Full text Link to item Cite

Neighborhood characteristics moderate effects of caregiving on glucose functioning.

Journal Article Psychosom Med · 2005 OBJECTIVE: Adverse neighborhood environments and caregiving for a relative with dementia are both stressors that have been associated with poor health. The present study examined the extent to which three self-report measures of neighborhood characteristic ... Full text Link to item Cite

Facets of personality and the phenomenology of autobiographical memory

Journal Article · November 1, 2004 The relationship between individual differences in autobiographical memory and personality was examined by having 118 undergraduates complete the NEO Personality Inventory after rating 15 word-cued autobiographical memories on 20 scales. The Openness to Fe ... Full text Open Access Cite

Prospective study of perceived stress in cardiac patients.

Journal Article Ann Behav Med · February 2004 BACKGROUND: Psychological stress is known to have a negative effect on the health and well-being of coronary artery disease (CAD) patients. Although the study of stress CAD samples has received considerable attention, few studies have examined the effects ... Full text Link to item Cite

Hostility as a predictor of survival in patients with coronary artery disease.

Journal Article Psychosom Med · 2004 OBJECTIVE: This article presents a reanalysis of an earlier study that reported a nonsignificant relation between the 50-item Cook-Medley Hostility Scale (CMHS) and survival in a sample of coronary patients. Since publication of those results, there have b ... Full text Link to item Cite

Community recruitment process by race, gender, and SES gradient: lessons learned from the Community Health and Stress Evaluation (CHASE) Study experience.

Journal Article J Community Health · December 2003 Recruitment of community participants for clinical research studies is a challenging task. When possible, community-based recruitment efforts should involve members of the targeted community in the planning, community preparation, and actual recruitment pr ... Full text Link to item Cite

Effect of smoking and sedentary behavior on the association between depressive symptoms and mortality from coronary heart disease.

Journal Article Am J Cardiol · September 1, 2003 It has been suggested that one of the mechanisms linking depression with elevated mortality risk is the association between depressive symptoms and other established coronary artery disease (CAD) risk factors, such as smoking and failure to exercise. The p ... Full text Link to item Cite

Self-blame, social introversion, and male suicides: Prospective data from a longitudinal study

Journal Article Archives of Suicide Research · April 21, 2003 This study examines the use of 7 Minnesota Multiphasic Personality Inventory (MMPI; Hathaway & Briggs, 1940) subscales in their ability to differentiate between male suicide completers and 1) clinically depressed men, and 2) a deceased control group consis ... Full text Cite

Another round in the mammography controversy.

Journal Article J Womens Health (Larchmt) · April 2003 PURPOSE: The October 2001 publication of a meta-analysis questioning the scientific basis for recommending screening mammography sparked yet a new flame of controversy about this issue. We conducted a national survey in March 2002 to provide information ab ... Full text Link to item Cite

Serotonin-related gene polymorphisms and central nervous system serotonin function.

Journal Article Neuropsychopharmacology · March 2003 Central nervous system (CNS) serotonergic function affects a wide range of biological and behavioral functions affecting health and disease. Our objective in this study was to determine whether functional polymorphisms of the genes that encode for the sero ... Full text Link to item Cite

Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender.

Journal Article Psychiatr Genet · March 2003 OBJECTIVE: The short variant of the serotonin transporter gene-linked functional polymorphic region (5-HTTLPR) has been associated with personality traits related to anxiety, hostility, and depression. We attempted to replicate findings suggesting a positi ... Full text Link to item Cite

Coping styles and personality domains related to menopausal stress.

Journal Article Womens Health Issues · 2003 PURPOSE: Examine the role of coping styles and personality domains in relationship to stress associated with menopause. DATA/INFORMATION: Data are from 170 women ages 45 to 54 who completed a mailed questionnaire and a telephone interview that assessed wom ... Full text Link to item Cite

Patterns of change in hostility from college to midlife in the UNC Alumni Heart Study predict high-risk status.

Journal Article Psychosom Med · 2003 OBJECTIVE: To examine hostility measured in college and patterns of change in hostility from college to midlife as predictors of high health-related risk later in midlife. METHODS: Logistic regression models were used to test hostility/risk associations. R ... Full text Link to item Cite

Associations among social support, income, and symptoms of depression in an educated sample: the UNC Alumni Heart Study.

Journal Article Int J Behav Med · 2003 It has been suggested that the inverse association between social support and depression may be stronger in persons with lower income. This study tested the support x income hypothesis in a sample of 2,472 individuals enrolled in the UNC Alumni Heart Study ... Full text Link to item Cite

Overview

Journal Article Advances in Cell Aging and Gerontology · January 1, 2003 Full text Cite

Evaluating participants' use of a hormone replacement therapy decision-making intervention.

Journal Article Patient Educ Couns · December 2002 BACKGROUND: Associations between optimal use of a tailored decision-aid and levels of accuracy of perceived breast cancer risk, confidence in decision-making, and satisfaction with decisions about HRT were evaluated in a randomized intervention trial with ... Full text Link to item Cite

Alcoholic beverage preference, diet, and health habits in the UNC Alumni Heart Study.

Journal Article Am J Clin Nutr · August 2002 BACKGROUND: Moderate alcohol intake is related to better health, and additional benefits may be associated with wine. However, beverage preference may be confounded by lifestyle factors related to health. OBJECTIVE: The goal was to describe the association ... Full text Link to item Cite

Behavioral medicine and aging.

Journal Article J Consult Clin Psychol · June 2002 A brief history of behavioral medicine and aging is followed by a series of perspectives that help to understand how age is used as a variable in this research, the relative importance of age to declines in cognitive functioning, and the impact of behavior ... Full text Link to item Cite

Hostility, race, and glucose metabolism in nondiabetic individuals.

Journal Article Diabetes Care · May 2002 OBJECTIVE: The present study was designed to determine whether hostility is differentially related to measures of glucose metabolism in African-Americans and Caucasians. RESEARCH DESIGN AND METHODS: The relationship of hostility, as measured by a subset of ... Full text Link to item Cite

Predictors of smoking cessation in patients with a diagnosis of coronary artery disease.

Journal Article J Cardiopulm Rehabil · 2002 PURPOSE: This study aimed to examine demographic, psychosocial, and clinical variables as predictors of smoking cessation in patients with coronary artery disease. METHODS: Smoking status and psychosocial variables were obtained at baseline. Participants w ... Full text Link to item Cite

Allelic differences in the serotonin transporter-linked polymorphic region in geriatric depression.

Journal Article Am J Geriatr Psychiatry · 2002 Previous studies have examined the role of genetic variations in the serotonin transporter-linked polymorphic region (5HTTLPR) in affective disorders. The authors studied 182 older depressed subjects and 107 elderly control subjects and obtained DNA for ge ... Link to item Cite

Terminal change in cognitive function: an updated review of longitudinal studies.

Journal Article Exp Aging Res · 2002 We provide an update to Siegler's (1975) review of the terminal change literature. Articles identified through MEDLINE, CANCERLIT, PUBMED, and PSYCINFO from 1975 to 2000 were examined. Lower levels of cognitive function are related to increased risk of mor ... Full text Link to item Cite

A path model of chronic stress, the metabolic syndrome, and coronary heart disease.

Journal Article Psychosom Med · 2002 OBJECTIVE: We tested a theoretical stress model cross-sectionally and prospectively that examined whether relationships of chronic stress, psychophysiology, and coronary heart disease (CHD) varied in older adult men (N = 47), older adult women not using ho ... Full text Link to item Cite

The relationship between hostility and behavioral risk factors for poor health in women veterans.

Journal Article Prev Med · December 2001 BACKGROUND: While previous research has generally supported a relationship between hostility and health risk behaviors, the majority of this research has been conducted in predominately male, highly educated, Caucasian samples. The current study was design ... Full text Link to item Cite

Racial differences in physician recommendation of hormone replacement therapy.

Journal Article Prev Med · December 2001 PURPOSE: Previous studies have suggested that black women may be less likely than white women to be offered and to take hormone replacement therapy (HRT). Thus, race and other factors associated with physician recommendation of HRT that may influence women ... Full text Link to item Cite

Are the salutogenic effects of social supports modified by income? A test of an "added value hypothesis".

Journal Article Health Psychol · May 2001 Older adults (54 men, 113 women; M age = 69.5 years) were examined to test the hypothesis that social supports would be more salutogenic (health promoting) for persons with lower incomes than for persons with higher incomes. Interactions of income and soci ... Link to item Cite

Personality and coping with a common stressor: cardiac catheterization.

Journal Article J Behav Med · February 2001 The association between coping and personality was examined in a sample of 204 cardiac catheterization patients who were asked to evaluate the use of specific coping strategies used to deal with their cardiac catheterization. Personality, as measured by th ... Full text Link to item Cite

Enhancing Recovery in Coronary Heart Disease (ENRICHD) study intervention: rationale and design.

Journal Article Psychosom Med · 2001 OBJECTIVE: Depression and low social support are risk factors for medical morbidity and mortality after acute MI. The ENRICHD study is a multicenter, randomized, controlled clinical trial of a cognitive-behavioral treatment for depression and low social su ... Link to item Cite

Central nervous system serotonin function and cardiovascular responses to stress.

Journal Article Psychosom Med · 2001 OBJECTIVE: The objective of this study was to evaluate the impact of indices of central nervous system (CNS) serotonin function on cardiovascular reactivity to mental stress. METHODS: Lumbar puncture was performed on 54 healthy volunteers to obtain cerebro ... Full text Link to item Cite

Depressive symptoms, menopausal status, and climacteric symptoms in women at midlife.

Journal Article Psychosom Med · 2001 OBJECTIVE: Previous studies have found increased rates of depression in women aged 45 to 54 years, but the factors that influence these rates are not understood. It was assessed whether higher rates of depressive symptoms were associated with menopausal st ... Full text Link to item Cite

Characteristics of socially isolated patients with coronary artery disease who are at elevated risk for mortality.

Journal Article Psychosom Med · 2001 OBJECTIVES: Social isolation has been linked to poor survival in patients with coronary artery disease (CAD). Few studies have closely examined the psychosocial characteristics of CAD patients who lack social contact. METHODS: Social isolation was examined ... Full text Link to item Cite

Cigarette smoking in veteran women: the impact of job strain.

Journal Article Womens Health Issues · 2001 To evaluate the health effects of role overload, the relationship between multiple role (i.e., worker, spouse, caretaker) strain and current cigarette smoking was examined. A cross-sectional survey of women veterans, aged 36-85 years, was performed measuri ... Full text Link to item Cite

Associations among NEO personality assessments and well-being at midlife: facet-level analyses.

Journal Article Psychol Aging · December 2000 The association between well-being and personality was examined in 2,379 middle-aged adults. Measures that parallel C. D. Ryffs (1989) psychological model were selected to assess well-being. The 30 facet scales of the NEO-PI-R were used to measure personal ... Full text Link to item Cite

Relation of subjective and received social support to clinical and self-report assessments of depressive symptoms in an elderly population.

Journal Article J Affect Disord · December 2000 BACKGROUND: The authors sought to evaluate the associations between depressive symptoms and social support in a sample drawn from a relatively understudied population - depressed elderly patients. The present study also used a multi-measure approach to ass ... Full text Link to item Cite

Psycho-social predictors of survival among centenarians

Journal Article Facts, Research and Intervention in Geriatrics · December 1, 2000 In this paper, we identified predictors of extreme survival among a group of 137 centenarians (75.9% women) participating in the Georgia Centenarian Study, of whom 21 were still living as of March 15, 1999. At the time of initial testing, centenarians had ... Cite

Personality at midlife: stability, intrinsic maturation, and response to life events.

Journal Article Assessment · December 2000 Although developmental theories and popular accounts suggest that midlife is a time of turmoil and change, longitudinal studies of personality traits have generally found stability of rank order and little or no change in mean levels. Using data from 2,274 ... Full text Link to item Cite

Self-perceptions of stability and change in personality at midlife: the UNC Alumni Heart Study.

Journal Article Assessment · December 2000 The finding of personality stability in adulthood may be counterintuitive to people who perceive a great deal of change in their own personality. The purpose of this study is to determine whether self-reported perceived changes in personality are associate ... Full text Link to item Cite

Reliability of interview-assessed hostility ratings across mode of assessment and time.

Journal Article J Pers Assess · October 2000 These studies addressed 2 questions concerning interview-based hostility assessments: whether they are affected if the interview is conducted face-to-face versus telephone and whether they are stable across an extended time period. In Study 1A, 54 students ... Full text Link to item Cite

Relationships among breast cancer perceived absolute risk, comparative risk, and worries.

Journal Article Cancer Epidemiol Biomarkers Prev · September 2000 When trying to predict breast cancer screening, it may be important to understand the relationships between perceived breast cancer risks and worries about getting breast cancer. This study examines the extent to which women's worries about breast cancer c ... Link to item Cite

Moderators of the effect of social support on depressive symptoms in cardiac patients.

Journal Article Am J Cardiol · August 15, 2000 Social support and depression have been shown to affect the prognosis of coronary patients, and social support has been found to influence depression in community and patient samples. We investigated the characteristics of coronary patients whose depressiv ... Full text Link to item Cite

Measurement of dietary intake in the UNC Alumni Heart Study. University of North Carolina.

Journal Article Prev Med · July 2000 BACKGROUND: Research needs to identify diet and disease associations to provide direction about effecting change in individuals with dietary behaviors that increase risk of chronic disease. Inclusion of dietary assessment in the University of North Carolin ... Full text Link to item Cite

Hostility predicts magnitude and duration of blood pressure response to anger.

Journal Article J Behav Med · June 2000 The hypothesis that hostile and nonhostile individuals would differ in both magnitude and duration of cardiovascular reactivity to relived anger was tested. Participants were 66 older adults (mean age, 62; 38 women and 28 men; 70% Caucasian American, 30% A ... Full text Link to item Cite

Anger proneness predicts coronary heart disease risk: prospective analysis from the atherosclerosis risk in communities (ARIC) study.

Journal Article Circulation · May 2, 2000 BACKGROUND: Increased research attention is being paid to the negative impact of anger on coronary heart disease (CHD). METHODS AND RESULTS: This study examined prospectively the association between trait anger and the risk of combined CHD (acute myocardia ... Full text Link to item Cite

Hostility in marital dyads: associations with depressive symptoms.

Journal Article J Behav Med · February 2000 We examined the relations of hostility (of self and spouse) with self-ratings of depressive symptoms in 898 spouse pairs. Self-ratings of hostility were initially examined as predictors of depression. Next, spouse self-ratings of hostility were added to th ... Full text Link to item Cite

Coronary catherization patient and wife's perceptions of social support: effects due to characteristics of recipient, provider, and their interaction.

Journal Article Int J Aging Hum Dev · 2000 This investigation explored relationships between coronary catherization patient and wife's characteristics and their perceptions of social support. Participants were 124 male patients undergoing diagnostic catherization to detect coronary artery disease ( ... Full text Link to item Cite

Depressive symptoms and survival of patients with coronary artery disease.

Journal Article Psychosom Med · 2000 OBJECTIVE: Multiple studies have shown that high levels of depressive symptoms increase the mortality risk of patients with established coronary disease. This investigation divided depressive symptoms into groups to assess their relative effectiveness in p ... Full text Link to item Cite

Social support and quality of life in patients with coronary artery disease.

Journal Article Qual Life Res · 2000 The relationship between perceived social support and domain-specific health-related quality of life (HRQOL) was examined in a sample of cardiac catheterization patients after considering age, gender, race, education, and coronary artery disease (CAD) seve ... Full text Link to item Cite

Relation between informant-rated personality and clinician-rated depression in patients with memory disorders.

Journal Article Neuropsychiatry Neuropsychol Behav Neurol · January 2000 OBJECTIVE: The goal of this study was to examine the convergent validity of informant-rated changes in depressive and related personality traits with clinician-assessed depression in memory-disordered patients. BACKGROUND: Depressive symptoms are frequent ... Link to item Cite

Premorbid personality predicts level of rated personality change in patients with Alzheimer disease.

Journal Article Alzheimer Dis Assoc Disord · 2000 Multiple studies of individuals with Alzheimer disease have substantiated significant levels of informant-rated change in several domains and facets of the Neuroticism-Extraversion-Openness Personality Inventory, including increases in Neuroticism and decr ... Full text Link to item Cite

The association between self-rated health and mortality in a well-characterized sample of coronary artery disease patients.

Journal Article Med Care · December 1999 BACKGROUND: The relationship between self-rated health and mortality after adjustment for sociodemographic variables, physician-rated comorbidities, disease severity, health-related quality of life (HRQOL), and psychosocial measures (depression, social sup ... Full text Link to item Cite

Stress, sleep problems, and immune function in persons with cancer histories

Journal Article Cancer Research, Therapy and Control · December 1, 1999 Problem. Data suggest that chronic stress, cancer history, sleep problems and clinical depression are associated with reduced natural killer cell activity (NKA), but few studies have examined whether in combination these variables have synergistic relation ... Cite

Age and distance to death in the Seattle Longitudinal Study

Journal Article Research on Aging · November 17, 1999 A series of hierarchical regression models was used to determine if time to death was a significant independent variable for level and seven-year change in intellectual performance for 1,214 community-dwelling adults. Distance to death explained a signific ... Full text Cite

The relationship between self-rated health and health status among coronary artery patients.

Journal Article J Aging Health · November 1999 OBJECTIVES: This study examined the descriptive relationship of self-rated health (SRH) with various psychosocial measures, sociodemographic variables, coronary artery disease (CAD) diagnostic/clinical measures, and medically abstracted comorbidities. METH ... Full text Link to item Cite

Osteoporosis risk factors: Association with use of hormone replacement therapy and with worry about osteoporosis

Journal Article Women's Health Issues · November 1, 1999 Objectives: To determine whether postmenopausal women with risk factors for osteoporosis are more likely to use hormone replacement therapy (HRT) or to worry about osteoporosis than women without risk factors. Method: Cross-sectional survey of postmenopaus ... Full text Cite

Trust, health, and longevity.

Journal Article J Behav Med · December 1998 Scores on the Rotter Interpersonal Trust Scale were evaluated as predictors of psychological well-being, functional health, and longevity in a sample of 100 men and women who were between 55 and 80 years old at baseline (mean age 66.8). Cross-sectionally, ... Full text Link to item Cite

Coronary heart disease moderates the relationship of chronic stress with the metabolic syndrome.

Journal Article Health Psychol · November 1998 Metabolic syndrome levels (MSLs) were compared in caregivers (CGs) of spouses with Alzheimer's disease who had diagnoses of coronary heart disease (CHD; n = 27) with non CGs with CHD diagnoses (n = 18), and CGs (n = 44) to non CGs (n = 52) free of CHD. MSL ... Full text Link to item Cite

Magnetic resonance imaging correlates of depression in early- and late-onset Alzheimer's disease.

Journal Article Biol Psychiatry · October 1, 1998 BACKGROUND: Depressive symptoms are frequent complications of Alzheimer's disease (AD). We hypothesized that AD patients with depression would be more likely than nondepressed AD patients to show deep white-matter, subcortical gray-matter, and periventricu ... Full text Link to item Cite

Differences in providers' beliefs about benefits and risks of hormone replacement therapy in managed care.

Journal Article J Womens Health · September 1998 Our objective was to determine if physician beliefs about the benefits and risks of hormone replacement therapy (HRT) differ by physician gender or specialty in a managed care setting. In a cross-sectional survey of providers in a health maintenance organi ... Full text Link to item Cite

Symptoms of depression and changes in body weight from adolescence to mid-life.

Journal Article Int J Obes Relat Metab Disord · July 1998 OBJECTIVE: To investigate the relationship of symptoms of depression to weight changes in healthy individuals of normal weight across a follow-up of over 20 y. PARTICIPANTS AND DESIGN: College students (3885 men and 841 women) were administered a self-repo ... Full text Link to item Cite

Measures of hostility as predictors of facial affect during social interaction: evidence for construct validity.

Journal Article Ann Behav Med · 1998 We assessed the construct validity of several self-report measures and an interview-based measure of hostility (Interpersonal Hostility Assessment Technique [IHAT]) by evaluating their associations with a behavioral indicator of hostile emotions (facial ex ... Full text Link to item Cite

Social support and hostility as predictors of depressive symptoms in cardiac patients one month after hospitalization: a prospective study.

Journal Article Psychosom Med · 1998 OBJECTIVE: Hospitalization for cardiac disease is associated with an increased risk for depression, which itself confers a poorer prognosis. Few prospective studies have examined the determinants of depression after hospitalization in cardiac patients, and ... Full text Link to item Cite

Psychosocial stress moderates the relationship of cancer history with natural killer cell activity.

Journal Article Ann Behav Med · 1998 Data suggest that both cancer history and psychosocial stress may be associated with reductions in natural killer cell activity (NKA). Therefore, we tested whether individual differences in cancer history, chronic/perceived stress, and their interactions w ... Full text Link to item Cite

Perceptions of menopausal stage and patterns of hormone replacement therapy use.

Journal Article J Womens Health · August 1997 In 1994, as part of their participation in the University of North Carolina Alumni Heart Study, 1101 women aged 45-51 years answered questions about their menopausal status and current use of hormone replacement therapy (HRT). Little is known about the use ... Full text Link to item Cite

Psychosocial correlates of job strain in a sample of working women.

Journal Article Arch Gen Psychiatry · June 1997 BACKGROUND: This study identifies potential mediators of job strain effects on health by determining whether psychosocial factors known to predict an increased risk of cardiovascular disease and all-cause mortality are higher among women who report high le ... Full text Link to item Cite

Surrogate assessment of coronary artery disease patients' functional capacity.

Journal Article Soc Sci Med · May 1997 An investigation of the surrogate assessment of coronary artery disease (CAD) patients' functional capacity was conducted using 193 patient and surrogate rater dyads. Mean age of patients and surrogate raters were 60.4 and 54.4 years, respectively. Patient ... Full text Link to item Cite

Relation of mood ratings and neurohormonal responses during daily life in employed women.

Journal Article Int J Behav Med · 1997 Diurnal variations in urinary norepinephrine, epinephrine, cortisol, and self-reported mood states were examined in 101 employed women. Urine was collected on 2 consecutive workdays at 3 time periods: (1) overnight, (2) daytime, and (3) evening. Self-repor ... Full text Link to item Cite

Stress in employed women: impact of marital status and children at home on neurohormone output and home strain.

Journal Article Psychosom Med · 1997 OBJECTIVE: To evaluate the biological and psychological effects of role overload, we examined the effects of marital (or partnership) status and parental status (defined as having children at home) on daily excretion of urinary catecholamines and cortisol ... Full text Link to item Cite

Stability in extraversion and aspects of social support at midlife.

Journal Article J Pers Soc Psychol · January 1997 This investigation used participants from the University of North Carolina Alumni Heart Study in an exploration of extraversion and aspects of social support at midlife. Results indicated that extraversion measured at college entry and at midlife was posit ... Full text Link to item Cite

Depression and long-term mortality risk in patients with coronary artery disease.

Journal Article Am J Cardiol · September 15, 1996 Previous research has established that patients with coronary artery disease (CAD) have an increased risk of death if they are depressed at the time of hospitalization. Follow-up periods have been short in these studies; therefore, the present investigatio ... Full text Link to item Cite

Psychometric characteristics of the Mini-Mental State Examination in a community population - A grade of membership analysis: Part I

Journal Article International Journal of Geriatric Psychiatry · May 1, 1996 The Mini-Mental State Examination (MMSE), a brief, widely used measure of cognitive status, was designed to assess functioning in five areas (orientation, registration, attention and calculation, recall and language). Using a grade of membership analysis, ... Full text Cite

Approaches to the nonparametric analysis of limited longitudinal data sets.

Journal Article Exp Aging Res · 1996 The traditional goals of longitudinal studies are many: consideration of stability and change; description of patterns of development and behavior; and understanding of the processes involved in disease, including disease onset, recovery, response to treat ... Full text Link to item Cite

The importance of distinguishing the belief in a just world for self versus for others: Implications for psychological well-being

Journal Article Personality and Social Psychology Bulletin · January 1, 1996 Studies have shown that the belief in a just world (BJW) is related to psychological well-being. The authors suggest that studies exploring this relationship might benefit by making the distinction between the BJW for self versus for others or in general. ... Full text Cite

Awareness of and responses to changes in the National Cancer Institute's guidelines for mammography in women aged 35-49

Journal Article Journal of Women's Health · January 1, 1996 In 1994, as part of their participation in the University of North Carolina UNC Alumni Heart Study (UNCAHS), 1134 women aged 35-49 years answered five questions designed to assess the impact of the National Cancer Institute's (NCI) changing recommendations ... Full text Cite

Correlates of perceived social support and equality of interpersonal relationships at mid-life.

Journal Article Int J Aging Hum Dev · 1996 An investigation into the correlates of perceived social support and the equality of interpersonal relationships at mid-life was conducted using a sample of 3954 adults from the University of North Carolina Alumni Heart Study (UNCAHS). Participants ranged ... Full text Link to item Cite

Do comparative self-appraisals during young adulthood predict adult personality?

Journal Article Psychol Aging · June 1995 Archival data from the University of North Carolina Alumni Heart Study were used to assess whether positive, neutral, and negative social comparisons assessed during college predicted the expression of personality during adulthood. College students in 1966 ... Full text Link to item Cite

Predictors of adoption of mammography in women under age 50.

Journal Article Health Psychol · May 1995 Women in the University of North Carolina Alumni Heart Study reported their knowledge of and attitudes toward mammography as well as their adoption of mammography by 1991. Personality measured in 1988-1989 at the age of 42 was associated with the pattern o ... Full text Link to item Cite

Personality and breast cancer screening behaviors

Journal Article Annals of Behavioral Medicine · December 1, 1994 This review examines findings on the relationship between personality and breast cancer screening behaviors. Because the literature is limited, data from the University of North Carolina Alumni Heart Study (UNCAHS) are presented showing the associations be ... Cite

Caregiver ratings of personality change in Alzheimer's disease patients: a replication.

Journal Article Psychol Aging · September 1994 Caregivers of 26 patients with Alzheimer's disease (AD) rated current and premorbid personality patterns with the NEO Personality Inventory. Results replicated previous findings on the degree of change reported in a previous group of patients with mixed me ... Full text Link to item Cite

A short MMPI scale to identify people likely to begin smoking.

Journal Article J Pers Assess · April 1994 An item analysis of the Minnesota Multiphasic Personality Inventory (MMPI) was conducted to develop questionnaires that best discriminated (a) individuals who ever smoked versus those who never smoked and (b) ex-smokers from current smokers. The analyses w ... Full text Link to item Cite

Personality measures as predictors of smoking initiation and cessation in the UNC Alumni Heart Study.

Journal Article Health Psychol · March 1994 MMPI data collected from a sample of college men and women during 1964-1967 were used to predict smoking initiation and cessation over a 20-year follow-up period. People who subsequently began smoking were more rebellious, impulsive, sensation seeking, and ... Full text Link to item Cite

Caffeine and cholesterol: interactions with hostility.

Journal Article Psychosom Med · 1994 The consumption of caffeinated beverages has been linked to elevated serum cholesterol and an increased risk of coronary disease, although the relationships are inconsistent across studies and remain controversial. The effect of caffeine on cholesterol and ... Full text Link to item Cite

The belief in a just world and perceptions of discrimination.

Journal Article J Psychol · July 1993 We examined the relationship between the belief in a just world and frequency of self-reported acts of personal discrimination. American adults with a strong belief in a just world reported fewer acts of personal discrimination against themselves than thos ... Full text Link to item Cite

Age differences in hostility among middle-aged and older adults.

Journal Article Psychol Aging · March 1993 Multiple measures of hostility were administered to middle-aged and older volunteers. There was a positive association between age and self-report measures reflecting hostile beliefs about others, including cynicism and suspiciousness. There was a weak inv ... Full text Link to item Cite

Longitudinal studies of aging in social and psychological gerontology

Journal Article Reviews in Clinical Gerontology · January 1, 1993 Full text Cite

Life goals, satisfaction, and self-rated health: preliminary findings.

Journal Article Exp Aging Res · 1993 Several recent studies have suggested that a better understanding of health and psychological well-being in later life requires insights into the life goals and motivations of research participants. However, goal importance has not been examined separately ... Full text Link to item Cite

Age and gender differences in the content scales of the Minnesota Multiphasic Personality Inventory.

Journal Article Exp Aging Res · 1993 We examined time of measurement, gender, and age differences on the nine content scales of the Minnesota Multiphasic Personality Inventory using data collected by three separate studies during the 1950s, 1960s and 1980s. No evidence was found for differenc ... Full text Link to item Cite

Using college alumni populations in epidemiologic research: the UNC Alumni Heart Study.

Journal Article J Clin Epidemiol · November 1992 The UNC Alumni Heart Study (UNCAHS) is a prospective study of the role of psychosocial factors, in particular hostility, in the development of coronary heart disease. The target population is composed of persons who completed the Minnesota Multiphasic Pers ... Full text Link to item Cite

Hostility during late adolescence predicts coronary risk factors at mid-life.

Journal Article Am J Epidemiol · July 15, 1992 Hostility, as measured by the Cook-Medley Hostility Scale of the Minnesota Multiphasic Personality Inventory, has been found to predict higher rates of both coronary heart disease and all-cause mortality. To evaluate one mechanism whereby hostility might c ... Full text Link to item Cite

Prognostic importance of social and economic resources among medically treated patients with angiographically documented coronary artery disease.

Journal Article JAMA · January 22, 1992 OBJECTIVE: To evaluate the hypothesis that diminished social and economic resources impact adversely on cardiovascular mortality in patients with coronary artery disease. DESIGN: Inception cohort study of patients undergoing cardiac catheterization from 19 ... Link to item Cite

Hostility during late adolescence predicts coronary risk factors at midlife

Journal Article American Journal of Epidemiology · 1992 Cite

Ratings of personality change in patients being evaluated for memory disorders.

Journal Article Alzheimer Dis Assoc Disord · 1991 Caregivers of 35 mildly to moderately memory-impaired patients rated current and premorbid personalities with the NEO Personality Inventory. We then examined changes in the five domains of personality tapped by the NEO. There were significant changes in fo ... Full text Link to item Cite

Hostility patterns and health implications: correlates of Cook-Medley Hostility Scale scores in a national survey.

Journal Article Health Psychol · 1991 Correlated Cook-Medley Hostility Scale (Ho) scores with sociodemographic variables in a national survey of 2,536 adults. Multiple regression models revealed that Ho scores were associated with race (p less than .0001), years of education (p less than .001) ... Full text Link to item Cite

Paradigms in developmental health psychology--from theory to application: introduction to a special issue.

Journal Article J Gerontol · July 1990 This brief introduction sets the background for, describes, and reviews the eight manuscripts that comprise this special issue of the Journal of Gerontology: Psychological Sciences. Given the topic of health, behavior, and aging it is noteworthy that these ... Full text Link to item Cite

Religious coping and personality in later life

Journal Article International Journal of Geriatric Psychiatry · January 1, 1990 A stratified random subsample of 100 older adults from long‐term participants of the Second Duke Longitudinal Study was interviewed concerning how they coped with three stressful event periods. Responses to open‐ended coping questions were categorized as r ... Full text Cite

Predicting personality in adulthood from college MMPI scores: implications for follow-up studies in psychosomatic medicine.

Journal Article Psychosom Med · 1990 To assess the long-term predictive utility of Minnesota Multiphasic Personality Inventory (MMPI) content scales, 1,960 individuals who had completed the MMPI in college in 1964 or 1965 were administered two measures of adult personality, the NEO Personalit ... Full text Link to item Cite

Type A behavior and survival: a follow-up study of 1,467 patients with coronary artery disease.

Journal Article Am J Cardiol · September 1, 1989 Patients with documented coronary artery disease, admitted to Duke Medical Center between 1974 and 1980, were assessed for type A behavior pattern and were followed until 1984. The relation of type A behavior to survival was tested using data from coronary ... Full text Link to item Cite

Religious and Non-Religious Coping: Impact on Adaptation in Later Life

Journal Article Journal of Religion and Aging · 1989 Cite

A caution on the use of the MMPI K-correction in research on psychosomatic medicine.

Journal Article Psychosom Med · 1989 The MMPI K scale is widely used to screen for invalid responses and to adjust substantive scale scores for defensiveness. In a normal volunteer sample, correlations of MMPI clinical scales and the Cook-Medley Hostility (HO) scale with self-reports and peer ... Full text Link to item Cite

Relationships between motivation and hostility among type A and type B middle-aged men

Journal Article Journal of Research in Personality · January 1, 1987 Relationships between aspects of personality and the Type A behavior pattern (TABP) were examined in a sample of 60 middle-aged men. TABP classification was determined by the Structured Interview (SI) and the Jenkins Activity Survey (JAS), while aspects of ... Full text Cite

Relationships between motivation and hostility among type A and type B middle-aged men

Journal Article Journal of Research in Personality · 1987 Relationships between aspects of personality and the Type A behavior pattern (TABP) were examined in a sample of 60 middle-aged men. TABP classification was determined by the Structured Interview (SI) and the Jenkins Activity Survey (JAS), while aspects of ... Cite

Suspiciousness, health, and mortality: a follow-up study of 500 older adults.

Journal Article Psychosom Med · 1987 Scores on Factor L of the 16 PF, a measure of suspiciousness that is closely related to the Cook and Medley hostility scale, predicted survival in a sample of 500 older men and women during a follow-up of approximately 15 years. Those individuals with scor ... Full text Link to item Cite

Patterns of intellectual development in later life.

Journal Article J Gerontol · July 1986 Temporal changes in 16 measures of cognitive and intellectual functioning (11 Wechsler Adult Intelligence Scale subtests, 3 Wechsler Memory Test subscales, 2 measures of reaction time) were studied in the full data set from the First Duke Longitudinal Stud ... Full text Link to item Cite

The normal psychology of the aging male: Sex differences in coping and perceptions of life events

Journal Article Journal of Geriatric Psychiatry · December 1, 1983 The data illustrate some important methodological considerations about the study of life events and the study of developmental data. As the data on the distribution of life events indicate, when individuals retell their life stories, events are rarely disc ... Cite

FUZZY AND CRISP SET-THEORETIC BASED CLASSIFICATION OF HEALTH AND DISEASE: A QUALITATIVE AND QUANTITATIVE COMPARISON.

Journal Article Proceedings of the Hawaii International Conference on System Science · December 1, 1983 Conventional cluster analyses of patient populations are intended to assist in the identification and characterization of groups which may represent etiological or pathological subtypes within a particular disease class. These methods have been criticized ... Cite

Fuzzy and crisp set-theoretic-based classification of health and disease. A qualitative and quantitative comparison.

Journal Article J Med Syst · August 1983 Conventional cluster analyses of patient populations are intended to assist in the identification and characterization of groups that may represent etiological or pathological subtypes within a particular disease class. These methods have been criticized a ... Full text Link to item Cite

Sex differences in coping and perceptions of life events.

Journal Article J Geriatr Psychiatry · 1983 These data illustrate some important methodological considerations about the study of life events and the study of developmental data. As the data on the distribution of life events indicate, when individuals retell their life stories, events are rarely di ... Link to item Cite

Cross-sectional and longitudinal patterns of three Wechsler Memory Scale Subtests.

Journal Article J Gerontol · March 1982 This study evaluated cross-sectional and longitudinal age relationships, after age 60, for three subtests of the Wechsler Memory Scale: logical memory, associate learning, and visual reproduction. Cross-sectional regression analyses indicated that age, sex ... Full text Link to item Cite

Locus of Control and Long-term Care

Journal Article The Journal of Applied Gerontology · January 1, 1982 Locus of control is a variable of high interest in the assessment and behavior of the elderly in long-term care (LTC) facilities. This study uses a situation-specific locus of control (LOC) index and controls for the influential variables in an LTC setting ... Full text Cite

Markov Network Analysis: suggestions for innovations in covariance structure analysis.

Journal Article Exp Aging Res · 1982 Studies of aging offer special methodological challenges to the researcher in that he must often examine the change of multiple correlated variables over time. We present a set of procedures that are specifically designed to model change in such multivaria ... Full text Link to item Cite

Methodological comments: From a symposium methodological considerations for aging research: Introduction to a symposium and methodological commentary

Journal Article Experimental Aging Research · January 1, 1982 This article introduces a set of papers which illustrate the application of multivariate techniques to problems in aging research. Multivariate research strategies raise new issues in the choice of sample size that are discussed. The papers reviewed in thi ... Full text Cite

Separating age, cohort, and time of measurement: analysis of variance or multiple regression.

Journal Article Exp Aging Res · 1981 This paper empirically compares the relative advantages of analysis of variance (ANOVA) and multiple regression (MR) approaches to the separation of age, cohort, and time of measurement effects in sequential research designs. The comparison utilizes four s ... Full text Link to item Cite

Intellectual ability among the elderly: Simultaneous cross-sectional and longitudinal comparisons

Journal Article Developmental Psychology · January 1, 1980 Made simultaneous cross-sectional and longitudinal comparisons of WAIS performances of 70 Ss. The comparisons were such that approximately 4 yrs separated the age groups both cross-sectionally and longitudinally. The groups were aged 60-63, 64-67, 68-71, a ... Full text Cite

Stress and adaptation in later life.

Journal Article J Gerontol · November 1979 The effects of five major life events, and of three types of resources, on the physical and social-psychological adaptation of 375 participants in a longitudinal study were examined. As expected, medical events had the most impact on physical adaptation, b ... Full text Link to item Cite

A long-term longitudinal study of intellectual ability of older adults: the matter of selective subject attrition.

Journal Article J Gerontol · March 1979 Two hundred and forty-six subjects aged 60 to 94 were tested with the WAIS at test session 1, the start of a longitudinal study which lasted approximately 20 years. The subject attrition from the first session to the last (session No. 11) was progressive a ... Full text Link to item Cite

Individual and community: normative conflicts in the development of a new therapeutic community for older persons.

Journal Article Int J Aging Hum Dev · 1979 This paper examines the role of ideology in the establishment of a new therapeutic community for geriatric patients in a state mental hospital. Contradictory role expectations, reflected both in staff-staff and in staff-patient relationship, interfered wit ... Full text Link to item Cite

Cautiousness and verbal learning in adulthood.

Journal Article J Gerontol · January 1978 Twenty-two young (age 17-21)and 22 old (age 60-74) men and women participated in an investigation designed to determine the extent to which age differences in omission errors and performance in a serial learning task are accounted for by cautiousness. Age ... Full text Link to item Cite

Sex differences in serial learning for aged persons with high verbal ability.

Journal Article Exp Aging Res · March 1977 Serial rote learning was examined in men and women with high verbal ability aged 60-74 years. No sex differences were found in total errors, commission errors, or omissions errors. The results are in accord with the findings reported in a study by Wilkie a ... Full text Link to item Cite

The perception of outcome-effort covariation in younger and older men

Journal Article Educational Gerontology · January 1, 1977 The subjects, 21 younger (average CA = 18.95, SD = 1.13) and 21 older (average CA = 68.62, SD = 4.75) men, participated in a bogus convergent-thinking task in which they rated their effort expenditure after experiencing varying degrees of success. It was p ... Full text Cite

Relation between preference for intermediate risk and adult age in men: A cross-cultural validation

Journal Article Developmental Psychology · November 1, 1976 Investigated the generalizability of the N. P. Chaubey (see record 1974-27278-001) finding of an inverse relation between adult age and magnitude of preference for intermediate risk in Asian Indian males. 11 17-21 yr old undergraduates and 11 60-74 yr old ... Full text Cite

Learning to live in a therapeutic community: a study of elderly inpatients.

Journal Article Int J Aging Hum Dev · 1976 Fifty-two elderly mental patients in a state hospital were transferred to a new milieu ward. In order to evaluate patient success in the unit, three outcome categories were defined nine months after the unit opened: discharge to the community, adjustment t ... Full text Link to item Cite

The terminal drop hypothesis: fact or artifact?

Journal Article Exp Aging Res · September 1975 Findings from eight longitudinal investigations were reviewed in order to evaluate the terminal drop hypothesis. The concept of terminal drop was seen to be more useful when partitioned into its component parts: the relationship between the level of cognit ... Full text Link to item Cite