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James Randolph Urbaniak

Virginia Flowers Baker Distinguished Professor Emeritus of Orthopaedic Surgery
Orthopaedic Surgery
Box 2912 Med Ctr, Durham, NC 27710
Sports Medicine Center in Finch Yeager Bldg, Frank Bassett Dr., Durham, NC 27710

Selected Publications


Outcomes of free vascularized fibular graft for post-traumatic osteonecrosis of the femoral head.

Journal Article Injury · December 2021 INTRODUCTION: Osteonecrosis of the femoral head (ONFH) can occur after traumatic injuries of the hip. Surgical treatment with total hip arthroplasty (THA) may not produce lifelong viability in younger patients. Free vascularized fibular graft (FVFG) has be ... Full text Link to item Cite

Anterior elbow release for post-traumatic flexion contractures in patients 21 years or younger.

Journal Article J Shoulder Elbow Surg · July 2020 HYPOTHESIS AND BACKGROUND: An elbow contracture in a young person can be a devastating problem. Significant contractures will lead to functional loss of the extremity. Appropriately performed contracture release can have profound implications on the overal ... Full text Link to item Cite

Vascular endothelial growth factor for the treatment of femoral head osteonecrosis: An experimental study in canines.

Journal Article World J Orthop · September 18, 2018 AIM: To evaluate the treatment of osteonecrosis of the femoral head (ONFH) with the use of vascular endothelial growth factor (VEGF). METHODS: In 30 mature beagles (6 groups of 5 beagles) ONFH was induced cryosurgically and one of the following solutions w ... Full text Link to item Cite

Vascularized fibular grafts for avascular necrosis after slipped capital femoral epiphysis: is hip preservation possible?

Journal Article Clin Orthop Relat Res · July 2013 BACKGROUND: Avascular necrosis (AVN) of the femoral head is a potential complication in patients with slipped capital femoral epiphysis (SCFE), radiographically occurring in 3-60%. This may lead to early hip fusion or hip arthroplasty. Free vascularized fi ... Full text Link to item Cite

Osteonecrosis of the femoral head in childhood malignancy.

Journal Article J Child Orthop · March 2013 PURPOSE: Children undergoing chemotherapeutic treatment of malignancies have up to a 9 % incidence of osteonecrosis. The purpose of this article is to determine the time from initiation of chemotherapy to the onset of symptoms and the diagnosis of osteonec ... Full text Link to item Cite

The vascularized fibular graft in precollapse osteonecrosis: is long-term hip preservation possible?

Journal Article Clin Orthop Relat Res · October 2012 BACKGROUND: Osteonecrosis of the femoral head (ONFH) is a debilitating condition affecting primarily young patients. Free vascularized fibular grafting (FVFG) may provide a durable means to preserve the femoral head. When used in the precollapse stages of ... Full text Link to item Cite

Free vascularized fibular grafting preserves athletic activity level in patients with osteonecrosis.

Journal Article J Surg Orthop Adv · 2012 Athletic patients with osteonecrosis of the femoral head have few desirable therapeutic options that preserve athletic ability. Because these patients are usually young and healthy, any procedure that avoids total hip arthroplasty would be most desirable. ... Full text Link to item Cite

An evidence-based review of a single surgeon's experience with endoscopic carpal tunnel release.

Journal Article J Surg Orthop Adv · 2012 Although introduced more than 20 years ago, endoscopic carpal tunnel release (ECTR) continues to generate debate and controversy among surgeons. This review examines a single surgeon's technique for ECTR over the past 13 years to better understand the effe ... Full text Link to item Cite

Replantation

Chapter · 2011 Cite

Cost-effectiveness analysis of free vascularized fibular grafting for osteonecrosis of the femoral head.

Journal Article J Surg Orthop Adv · 2011 Management of symptomatic pre-collapse osteonecrosis of the femoral head continues to be controversial. Patients are often young and active, therefore hip-preserving procedures such as free vascularized fibular grafting (FVFG) have been developed to reliev ... Link to item Cite

Invited commentary.

Journal Article J Orthop Trauma · April 2010 Full text Link to item Cite

Free vascularized fibular transfer for femoral head osteonecrosis: donor and graft site morbidity.

Journal Article J Bone Joint Surg Am · August 2009 BACKGROUND: Autogenous vascularized fibular transfer is used effectively for a variety of complex reconstructive procedures. Published series demonstrating the morbidity associated with its harvest have, understandably, been relatively small, and graft sit ... Full text Link to item Cite

Vascularised fibular graft in the management of femoral head osteonecrosis: twenty years later.

Journal Article J Bone Joint Surg Br · March 2009 The management of osteonecrosis of the femoral head ranges from symptomatic therapy to total hip replacement. Conservative treatment is effective only in small, early-stage lesions. Free vascularised fibular grafting has provided more consistently successf ... Full text Link to item Cite

Free Vascularized Fibular Grafting for treatment of osteonecrosis of the femoral head secondary to hip dislocation.

Journal Article Microsurgery · 2009 Traumatic dislocation of the hip results in osteonecrosis of the femoral head (ONFH) or avascular necrosis (AVN) in approximately 40% of patients. This high-energy event causes an ischemic insult to the femoral head that may lead to ONFH. Here, we investig ... Full text Link to item Cite

Donor sites for pedicled skeletal grafts of the hand, wrist, and forearm.

Journal Article Microsurgery · 2009 Pedicled bone and periosteal grafts provide successful reconstruction of skeletal problems of the distal radius, wrist, and hand. The purpose of this study was to evaluate the available alternatives and to propose the most suitable skeletal grafts for the ... Full text Link to item Cite

Vascularized fibular grafting for osteonecrosis of the femoral head with unusual indications.

Journal Article Clin Orthop Relat Res · May 2008 We retrospectively reviewed the charts of 154 patients of various subgroups treated with the free vascularized fibular graft procedure for osteonecrosis of the femoral head (ONFH), evaluating pre- and postoperative Harris hip scores, hip range of motion, r ... Full text Link to item Cite

Free vascularized fibular grafting for the treatment of osteonecrosis of the femoral head

Journal Article Techniques in Orthopaedics · March 1, 2008 We report on the use of the free vascularized fibular graft (FVFG) as an effective surgical procedure to address the challenging clinical diagnosis of osteonecrosis of the femoral head. The senior author (JRU) has been performing the procedure for approxim ... Full text Cite

Outcomes of free vascularized fibular graft for post-traumatic osteonecrosis of the femoral head.

Journal Article Injury · December 2021 INTRODUCTION: Osteonecrosis of the femoral head (ONFH) can occur after traumatic injuries of the hip. Surgical treatment with total hip arthroplasty (THA) may not produce lifelong viability in younger patients. Free vascularized fibular graft (FVFG) has be ... Full text Link to item Cite

Anterior elbow release for post-traumatic flexion contractures in patients 21 years or younger.

Journal Article J Shoulder Elbow Surg · July 2020 HYPOTHESIS AND BACKGROUND: An elbow contracture in a young person can be a devastating problem. Significant contractures will lead to functional loss of the extremity. Appropriately performed contracture release can have profound implications on the overal ... Full text Link to item Cite

Vascular endothelial growth factor for the treatment of femoral head osteonecrosis: An experimental study in canines.

Journal Article World J Orthop · September 18, 2018 AIM: To evaluate the treatment of osteonecrosis of the femoral head (ONFH) with the use of vascular endothelial growth factor (VEGF). METHODS: In 30 mature beagles (6 groups of 5 beagles) ONFH was induced cryosurgically and one of the following solutions w ... Full text Link to item Cite

Vascularized fibular grafts for avascular necrosis after slipped capital femoral epiphysis: is hip preservation possible?

Journal Article Clin Orthop Relat Res · July 2013 BACKGROUND: Avascular necrosis (AVN) of the femoral head is a potential complication in patients with slipped capital femoral epiphysis (SCFE), radiographically occurring in 3-60%. This may lead to early hip fusion or hip arthroplasty. Free vascularized fi ... Full text Link to item Cite

Osteonecrosis of the femoral head in childhood malignancy.

Journal Article J Child Orthop · March 2013 PURPOSE: Children undergoing chemotherapeutic treatment of malignancies have up to a 9 % incidence of osteonecrosis. The purpose of this article is to determine the time from initiation of chemotherapy to the onset of symptoms and the diagnosis of osteonec ... Full text Link to item Cite

The vascularized fibular graft in precollapse osteonecrosis: is long-term hip preservation possible?

Journal Article Clin Orthop Relat Res · October 2012 BACKGROUND: Osteonecrosis of the femoral head (ONFH) is a debilitating condition affecting primarily young patients. Free vascularized fibular grafting (FVFG) may provide a durable means to preserve the femoral head. When used in the precollapse stages of ... Full text Link to item Cite

Free vascularized fibular grafting preserves athletic activity level in patients with osteonecrosis.

Journal Article J Surg Orthop Adv · 2012 Athletic patients with osteonecrosis of the femoral head have few desirable therapeutic options that preserve athletic ability. Because these patients are usually young and healthy, any procedure that avoids total hip arthroplasty would be most desirable. ... Full text Link to item Cite

An evidence-based review of a single surgeon's experience with endoscopic carpal tunnel release.

Journal Article J Surg Orthop Adv · 2012 Although introduced more than 20 years ago, endoscopic carpal tunnel release (ECTR) continues to generate debate and controversy among surgeons. This review examines a single surgeon's technique for ECTR over the past 13 years to better understand the effe ... Full text Link to item Cite

Replantation

Chapter · 2011 Cite

Cost-effectiveness analysis of free vascularized fibular grafting for osteonecrosis of the femoral head.

Journal Article J Surg Orthop Adv · 2011 Management of symptomatic pre-collapse osteonecrosis of the femoral head continues to be controversial. Patients are often young and active, therefore hip-preserving procedures such as free vascularized fibular grafting (FVFG) have been developed to reliev ... Link to item Cite

Invited commentary.

Journal Article J Orthop Trauma · April 2010 Full text Link to item Cite

Free vascularized fibular transfer for femoral head osteonecrosis: donor and graft site morbidity.

Journal Article J Bone Joint Surg Am · August 2009 BACKGROUND: Autogenous vascularized fibular transfer is used effectively for a variety of complex reconstructive procedures. Published series demonstrating the morbidity associated with its harvest have, understandably, been relatively small, and graft sit ... Full text Link to item Cite

Vascularised fibular graft in the management of femoral head osteonecrosis: twenty years later.

Journal Article J Bone Joint Surg Br · March 2009 The management of osteonecrosis of the femoral head ranges from symptomatic therapy to total hip replacement. Conservative treatment is effective only in small, early-stage lesions. Free vascularised fibular grafting has provided more consistently successf ... Full text Link to item Cite

Free Vascularized Fibular Grafting for treatment of osteonecrosis of the femoral head secondary to hip dislocation.

Journal Article Microsurgery · 2009 Traumatic dislocation of the hip results in osteonecrosis of the femoral head (ONFH) or avascular necrosis (AVN) in approximately 40% of patients. This high-energy event causes an ischemic insult to the femoral head that may lead to ONFH. Here, we investig ... Full text Link to item Cite

Donor sites for pedicled skeletal grafts of the hand, wrist, and forearm.

Journal Article Microsurgery · 2009 Pedicled bone and periosteal grafts provide successful reconstruction of skeletal problems of the distal radius, wrist, and hand. The purpose of this study was to evaluate the available alternatives and to propose the most suitable skeletal grafts for the ... Full text Link to item Cite

Vascularized fibular grafting for osteonecrosis of the femoral head with unusual indications.

Journal Article Clin Orthop Relat Res · May 2008 We retrospectively reviewed the charts of 154 patients of various subgroups treated with the free vascularized fibular graft procedure for osteonecrosis of the femoral head (ONFH), evaluating pre- and postoperative Harris hip scores, hip range of motion, r ... Full text Link to item Cite

Free vascularized fibular grafting for the treatment of osteonecrosis of the femoral head

Journal Article Techniques in Orthopaedics · March 1, 2008 We report on the use of the free vascularized fibular graft (FVFG) as an effective surgical procedure to address the challenging clinical diagnosis of osteonecrosis of the femoral head. The senior author (JRU) has been performing the procedure for approxim ... Full text Cite

Proteasome inhibitor attenuates skeletal muscle reperfusion injury by blocking the pathway of nuclear factor-kappaB activation.

Journal Article Plast Reconstr Surg · December 2007 BACKGROUND: Nuclear factor-kappaB is a key transcriptional factor in the regulation of inflammatory factors that are involved in tissue reperfusion injury, but conflicting data have been presented in the literature. The proteasome regulates proteins that c ... Full text Link to item Cite

Profile.

Journal Article J Hand Surg Eur Vol · October 2007 Full text Link to item Cite

Free vascularized fibular grafting following failed core decompression for femoral head osteonecrosis.

Journal Article J Arthroplasty · August 2007 The results of treatment of femoral head osteonecrosis with free vascularized fibular grafting (FVFG) following failed core decompression (core decompression-FVFG [CD-FVFG] group: 32 hips) were reviewed and compared with those of a control group that under ... Full text Link to item Cite

In Memorium: Frank H. Bassett III, MD (1928-2007)

Journal Article The American Journal of Sports Medicine · June 2007 Full text Cite

Synovial fluid metabolites in osteonecrosis.

Journal Article Rheumatology (Oxford) · March 2007 OBJECTIVES: Osteonecrosis of the femoral head results from interruption of the vascular supply and eventual death of the cellular portion of bone. Effective methods of monitoring response to treatment are needed. Our aim was to evaluate synovial fluid meta ... Full text Link to item Cite

Commentary

Journal Article The Journal of Bone & Joint Surgery · February 2007 Full text Cite

T.F. Roush, S.A. Olson, R. Pietrobon, L. Braga, and J.R. Urbaniak reply [4]

Journal Article Journal of Bone and Joint Surgery · January 1, 2007 Cite

Hip incision planning for free vascularized fibular grafting of the proximal femur: a handy tip.

Journal Article J Surg Orthop Adv · 2007 Free vascularized fibula graft surgery has been shown to be successful in the treatment of osteonecrosis of the femoral head. Refinements in the surgical technique have greatly decreased patient morbidity and overall surgical time. Careful placement of the ... Link to item Cite

Avascular necrosis of the femoral head: role of vascularized bone grafts.

Journal Article Orthop Clin North Am · January 2007 This article presents the history and development of as well as the results from the various techniques of vascularized bone grafting for the treatment of osteonecrosis (ON) of the femoral head. The authors have treated more than 2600 patients who had femo ... Full text Link to item Cite

Influence of acetabular coverage on hip survival after free vascularized fibular grafting for femoral head osteonecrosis.

Journal Article J Bone Joint Surg Am · October 2006 BACKGROUND: Osteonecrosis of the femoral head frequently results in collapse of the head and subsequent arthrosis of the joint. Surgical treatment has been based entirely on the evaluation of the femoral side of the hip joint, with little consideration giv ... Full text Link to item Cite

A Tribute to J. Leonard Goldner

Journal Article Hand Clinics · August 1, 2006 Full text Cite

Intermittent pneumatic compression regulates expression of nitric oxide synthases in skeletal muscles.

Journal Article J Biomech · 2006 This study investigated the effects of intermittent pneumatic compression (IPC) on expression of nitric oxide synthase (NOS) isoforms in compressed (anterior tibialis, AT) and uncompressed (cremaster muscles, CM) skeletal muscles. Following IPC application ... Full text Link to item Cite

Biology of the vascularized fibular graft

Journal Article · December 1, 2005 In the practice of orthopedics, bone grafting is a common procedure used to enhance the regeneration of bone and lead to the restoration of skeletal integrity. Bony regeneration is needed to reconstruct a wide variety of traumatic, developmental, degenerat ... Full text Cite

Pediatric femoral avascular necrosis after pyarthrosis: use of free vascularized fibular grafting.

Journal Article Clin Orthop Relat Res · October 2005 Pyarthrosis of a child's hip can lead to osteonecrosis of the femoral head. Symptomatic treatment options for this condition are limited. We supposed that free vascularized fibula autografting would improve range of motion, decrease pain, and increase func ... Full text Link to item Cite

Skeletal muscle reperfusion injury is enhanced in extracellular superoxide dismutase knockout mouse.

Journal Article Am J Physiol Heart Circ Physiol · July 2005 This study investigates the role of extracellular SOD (EC-SOD), the major extracellular antioxidant enzyme, in skeletal muscle ischemia and reperfusion (I/R) injury. Pedicled cremaster muscle flaps from homozygous EC-SOD knockout (EC-SOD-/-) and wild-type ... Full text Link to item Cite

The effects of exogenous nitric oxide donor on motor functional recovery of reperfused peripheral nerve.

Journal Article J Hand Surg Am · May 2005 PURPOSE: To investigate the effects of the nitric oxide donor S-nitroso-N-acetylcysteine (SNAC) on motor functional recovery of reperfused rat sciatic nerve. METHODS: Seventy-eight rats were divided into groups treated with SNAC (100 nmol/100 g/min), methy ... Full text Link to item Cite

Replantation

Chapter · 2005 Cite

Vascularized periosteal flaps of distal forearm and hand.

Journal Article J Trauma · January 2005 BACKGROUND: Vascularized periosteal flaps (VPFs) are flexible osteogenic flaps, suitable for the reconstruction of small skeletal defects. Pedicled VPFs, harvested near the recipient site, minimize donor-site morbidity and procedure duration. The donor sit ... Full text Link to item Cite

Addition of nitric oxide donor S-nitroso-N-acetylcysteine to selective iNOS inhibitor 1400W further improves contractile function in reperfused skeletal muscle.

Journal Article Microsurgery · 2005 This study examines the effects of combination therapy with the nitric oxide (NO) donor S-nitroso-N-acetylcysteine (SNAC) and the iNOS inhibitor N-(3-(aminomethyl)benzyl) acetamidine (1400W) on contractile function in reperfused rat skeletal muscle. The ri ... Full text Link to item Cite

Inhibition of iNOS attenuates skeletal muscle reperfusion injury in extracellular superoxide dismutase knockout mice.

Journal Article Microsurgery · 2005 Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are closely involved in the mechanism of skeletal muscle ischemia/reperfusion (I/R) injury. This study was designed to determine the effects of inducible nitric oxide synthase (iNOS) inhibit ... Full text Link to item Cite

Reperfusion injury in skeletal muscle is reduced in inducible nitric oxide synthase knockout mice.

Journal Article J Appl Physiol (1985) · October 2004 Inducible nitric oxide synthase (iNOS) participates in many pathological events, and selective inhibition of iNOS has been shown to reduce ischemia-reperfusion (I/R) injury in different tissues. To further confirm its role in this injury process, I/R injur ... Full text Link to item Cite

Anterior release of the elbow for extension loss.

Journal Article J Bone Joint Surg Am · September 2004 BACKGROUND: There are many causes of elbow contracture. When nonoperative techniques fail to increase the arc of motion of the elbow, surgical intervention may be indicated. The purpose of this study was to report the outcomes of surgical correction, predo ... Full text Link to item Cite

The effects of N(omega)-propyl-L-arginine on reperfusion injury of skeletal muscle.

Journal Article Nitric Oxide · August 2004 N(omega)-Propyl-L-arginine (NPA) is reported to be a highly selective inhibitor of neuronal nitric oxide synthase (nNOS). This in vivo study observed its role in ischemia/reperfusion (I/R) injury in rat skeletal muscle. Our results showed that NPA infusion ... Full text Link to item Cite

Results of free vascularized fibular grafting for femoral head osteonecrosis in patients with systemic lupus erythematosus.

Journal Article Orthop Clin North Am · July 2004 Osteonecrosis of the femoral head is a known complication of systemic lupus erythematosus. Patients often require surgical intervention at an early age. Options include total hip arthroplasty, core decompression, and free vascularized fibular grafting. Bec ... Full text Link to item Cite

Analysis of failures after vascularized fibular grafting in femoral head necrosis.

Journal Article Orthop Clin North Am · July 2004 Evaluation of graft-host bone interactions after failed vascularized fibular grafting of femoral head necrosis may elucidate the reasons for failure of the procedure. According to the authors' study, the vascularized fibula implanted into the femoral head ... Full text Link to item Cite

Osteonecrosis of the human skeleton.

Journal Article Orthop Clin North Am · July 2004 Full text Link to item Cite

Nitric oxide involvement in reperfusion injury of denervated muscle.

Journal Article J Hand Surg Am · July 2004 PURPOSE: To investigate whether inhibition of inducible nitric oxide synthase (iNOS) improves microcirculation in denervated and reperfused skeletal muscle. METHODS: The cremaster muscles of 52 rats received iNOS inhibitor 1400W (3 mg/kg) or phosphate buff ... Full text Link to item Cite

Coagulation abnormalities in patients with hip osteonecrosis.

Journal Article Orthop Clin North Am · July 2004 The relatively high frequency of coagulation abnormalities in patients with hip osteonecrosis might represent increased risk factors for the development of bone necrosis by predisposing these patients to thromboembolic phenomena. The recognition of this as ... Full text Link to item Cite

Free vascularized fibular grafting for the treatment of postcollapse osteonecrosis of the femoral head. Surgical technique.

Journal Article J Bone Joint Surg Am · March 2004 BACKGROUND: Osteonecrosis of the femoral head, a disease primarily affecting young adults, is often associated with collapse of the articular surface and subsequent arthrosis. Free vascularized fibular grafting has been reported to be successful for patien ... Full text Link to item Cite

Inhibition of iNOS with 1400W improves contractile function and alters nos gene and protein expression in reperfused skeletal muscle.

Journal Article Microsurgery · 2004 This study examined the effects of 1400W, an inhibitor of inducible nitric oxide (iNOS), on contractile function and iNOS expression in reperfused skeletal muscle. The right extensor digitorum longus (EDL) muscle of 104 rats underwent a sham operation or 3 ... Full text Link to item Cite

NF-kappaB p65 involves in reperfusion injury and iNOS gene regulation in skeletal muscle.

Journal Article Microsurgery · 2004 This study investigated the effects of inhibition of NF-kappaB activation on microcirculation and inducible NOS expression in reperfused rat cremaster muscle. The muscle from 16 rats underwent 5-h ischemia and 90-min reperfusion. Each rat received NF-kappa ... Full text Link to item Cite

Physicians and health professionals with osteonecrosis of the femoral head: results of management with free vascularized fibular grafting.

Journal Article J Surg Orthop Adv · 2004 Outcomes of free vascularized fibular grafting for the treatment of femoral head (FH) osteonecrosis between 1) physicians/health professionals and 2) a comparison group of the population at large was performed. Twenty-one healthcare providers (32 hips) wer ... Link to item Cite

Free vascularized fibular grafts for reconstruction of skeletal defects.

Journal Article J Am Acad Orthop Surg · 2004 Nourished by the peroneal vessels, the versatile free vascularized fibular graft can be transferred to reconstruct skeletal defects of the extremities. It may be combined with skin, fascia, muscle, and growth-plate tissue to address the needs of the recipi ... Full text Link to item Cite

Drug therapy increases bone density in osteonecrosis of the femoral head in canines.

Journal Article J Surg Orthop Adv · 2004 Although many different pathogenetic mechanisms have been proposed for osteonecrosis of the femoral head, the repair process leads to structural collapse when bone resorption exceeds production. The purpose of the current study was to determine the effects ... Link to item Cite

Bone grafting for osteonecrosis of the femoral head

Journal Article Seminars in Arthroplasty JSES · January 1, 2004 There has been a recent explosion of information relating to the etiology, pathophysiology, and treatment of avascular necrosis, or osteonecrosis, of the femoral head; however, few definitive conclusions have been made regarding either its development or t ... Full text Cite

Treatment of the severely traumatized elbow by allograft replacement: Twenty year experience

Conference PROCEEDINGS OF THE 9TH CONGRESS OF THE INTERNATIONAL FEDERATION OF SOCIETIES FOR SURGERY OF THE HAND · January 1, 2004 Link to item Cite

Free vascularized fibular grafting for the treatment of postcollapse osteonecrosis of the femoral head.

Journal Article J Bone Joint Surg Am · June 2003 BACKGROUND: Osteonecrosis of the femoral head, a disease primarily affecting young adults, is often associated with collapse of the articular surface and subsequent arthrosis. Free vascularized fibular grafting has been reported to be successful for patien ... Full text Link to item Cite

Hip arthroplasty after failed free vascularized fibular grafting for osteonecrosis in young patients.

Journal Article J Arthroplasty · June 2003 This study reports the results of total hip arthroplasty (THA) for osteonecrosis after failed free vascularized fibular grafting (FVFG) at a 5-year minimum follow-up. In this study, 73 patients (89 THA) were treated for failed FVFG, and survival of THA was ... Full text Link to item Cite

Reperfusion injury is reduced in skeletal muscle by inhibition of inducible nitric oxide synthase.

Journal Article J Appl Physiol (1985) · April 2003 Featured Publication This study evaluated the effects of the selective inducible nitric oxide synthase (iNOS) inhibitor N-[3-(aminomethyl)benzyl]acetamidine (1400W) on the microcirculation in reperfused skeletal muscle. The cremaster muscles from 32 rats underwent 5 h of ische ... Full text Link to item Cite

Heterotopic ossification after treatment of femoral head osteonecrosis with free vascularized fibular graft.

Journal Article J Arthroplasty · January 2003 Featured Publication This study evaluated patients with heterotopic ossification after implantation of a free vascularized fibular graft for the treatment of femoral head osteonecrosis. We hypothesized that the osteogenic tendency of these patients might enhance the graft-host ... Full text Link to item Cite

Osteonecrosis of the hip: management in the 21st century.

Journal Article Instr Course Lect · 2003 Osteonecrosis of the femoral head is a progressive condition that often leads to collapse of the femoral head. The ultimate goal in the treatment for osteonecrosis of the hip is preservation of the femoral head. However, the condition is difficult to treat ... Link to item Cite

C1-esterase inhibitor and a novel peptide inhibitor improve contractile function in reperfused skeletal muscle.

Journal Article Microsurgery · 2003 To determine the role of inhibition of complement activation in the contractile function of skeletal muscle ischemia-reperfusion (I/R) injury, the rat extensor digitorum longus (EDL) muscles underwent 3 h ischemia and received human C1-esterase inhibitor ( ... Full text Link to item Cite

Free vascularized fibular bone grafting in the management of femoral neck nonunion in patients younger than fifty years.

Journal Article J Orthop Trauma · August 2002 PURPOSE: The incidence of nonunion and osteonecrosis after femoral neck fracture has been well documented. In older patients implant arthroplasty is well established as an acceptable treatment of these problems. However, in the younger population alternati ... Full text Link to item Cite

Genetic etiology does not supplant the need to understand orthopaedic disorders.

Journal Article Clinical orthopaedics and related research · August 2002 Cite

Femoral head osteochondral lesions in painful hips of athletes: MR imaging findings.

Journal Article AJR Am J Roentgenol · April 2002 OBJECTIVE: This study describes the MR imaging findings of focal osteochondral lesions found in the hips of 11 athletes with persistent pain and normal findings on radiographs. CONCLUSION: Osteochondral lesions of the femoral head are seen on MR imaging as ... Full text Link to item Cite

Role of nitric oxide in vasodilation in upstream muscle during intermittent pneumatic compression.

Journal Article J Appl Physiol (1985) · February 2002 Featured Publication This study investigated the dosage effects of nitric oxide synthase (NOS) inhibitor N(G)-monomethyl-L-arginine (L-NMMA) on intermittent pneumatic compression (IPC)-induced vasodilation in uncompressed upstream muscle and the effects of IPC on endothelial N ... Full text Link to item Cite

Effect of a nitric oxide donor on microcirculation of acutely denervated skeletal muscle during reperfusion.

Journal Article J Reconstr Microsurg · January 2002 The authors have shown that exogenous nitric oxide (NO) protects innervated skeletal muscle against reperfusion injury. This study further evaluated the effects of exogenous NO donor on denervated skeletal muscle. Forty-eight denervated rat cremaster muscl ... Full text Link to item Cite

Osteonecrosis of the hip: Management in the twenty-first century

Journal Article Journal of Bone and Joint Surgery - Series A · January 1, 2002 Full text Cite

Gene and protein expressions of nitric oxide synthases in ischemia-reperfused peripheral nerve of the rat.

Journal Article Am J Physiol Cell Physiol · September 2001 Featured Publication This study examined mRNA and protein expressions of neuronal (nNOS), inducible (iNOS), and endothelial nitric oxide synthases (eNOS) in peripheral nerve after ischemia-reperfusion (I/R). Sixty-six rats were divided into the ischemia only and I/R groups. On ... Full text Link to item Cite

Comparison of continuous and interrupted suture techniques in microvascular anastomosis.

Journal Article J Hand Surg Am · May 2001 Featured Publication We evaluated the efficacy of the continuous suture technique (CST) in arteries and veins with varying external diameters (ED). In study 1 a direct end-to-end anastomosis was performed in 5 groups of animals (n = 15 in each group): group 1, rabbit carotid a ... Full text Link to item Cite

Treatment of osteonecrosis in the hip of pediatric patients by free vascularized fibular graft.

Journal Article Clin Orthop Relat Res · May 2001 The purpose of the current study was to review the demographics and etiologies of symptomatic femoral head osteonecrosis in the pediatric and adolescent population and to assess the results of treatment using free vascularized fibular grafting. A group of ... Full text Link to item Cite

Hemorrhage and thrombus formation in early experimental osteonecrosis.

Journal Article Clin Orthop Relat Res · May 2001 The aim of the current study was to test the hypothesis that the induction of an underlying immunologic condition in rabbits may enhance the development of steroid-induced osteonecrosis. Thirty-five adult rabbits were divided into four groups. Group I: 10 ... Full text Link to item Cite

Osteonecrosis.

Journal Article Clin Orthop Relat Res · May 2001 Link to item Cite

Symposium - Update on osteonecrosis of the hip - Editorial comment

Journal Article CLINICAL ORTHOPAEDICS AND RELATED RESEARCH · May 1, 2001 Link to item Cite

Free vascularized fibular grafting of the femoral head for the treatment of osteonecrosis

Journal Article Techniques in Orthopaedics · January 1, 2001 Osteonecrosis of the femoral head is a debilitating disease that primarily affects the young adult. As total hip arthroplasty is undesirable in this population, many alternatives to femoral head salvage have been reported; unfortunately, these options have ... Full text Cite

iNOS inhibitor improves microcirculation of reperfused skeletal muscle

Conference PROCEEDINGS OF THE INAUGURAL CONGRESS OF THE WORLD SOCIETY FOR RECONSTRUCTIVE MICROSURGERY · January 1, 2001 Link to item Cite

One donor nerve with two recipient sites of end-to-side neurorrhaphies (An experimental study)

Conference PROCEEDINGS OF THE INAUGURAL CONGRESS OF THE WORLD SOCIETY FOR RECONSTRUCTIVE MICROSURGERY · January 1, 2001 Link to item Cite

Pregnancy-related avascular necrosis.

Journal Article J Bone Joint Surg Am · October 2000 Full text Link to item Cite

Pregnancy-Related Avascular Necrosis

Journal Article The Journal of Bone and Joint Surgery-American Volume · October 2000 Full text Cite

Blockade of L-selectin attenuates reperfusion injury in a rat model.

Journal Article J Reconstr Microsurg · April 2000 Ischemia/reperfusion (I/R) injury appears to be a significant neutrophil-dependent component and may be ameliorated by blocking leukocyte-endothelial adhesion. Using a rat extensor digitorum longus (EDL) muscle model, the present study tested the hypothesi ... Full text Link to item Cite

End-to-side nerve repair. A review.

Journal Article Hand Clin · February 2000 Featured Publication In recent years, there has been a resurgence of end-to-side peripheral nerve repair. This technique offers a management of a peripheral nerve defect in the absence of a suitable proximal stump. Although numerous animal laboratory investigations demonstrate ... Link to item Cite

Correspondence

Journal Article The Journal of Bone and Joint Surgery-American Volume · February 2000 Full text Cite

Correspondence

Journal Article The Journal of Bone and Joint Surgery-American Volume · February 2000 Full text Cite

Correspondence

Journal Article The Journal of Bone and Joint Surgery-American Volume · February 2000 Full text Cite

Letter to the editor [2] (multiple letters)

Journal Article Journal of Bone and Joint Surgery · January 1, 2000 Cite

The hypothenar fat flap for revision carpal tunnel surgery.

Journal Article Tech Hand Up Extrem Surg · December 1999 Full text Link to item Cite

Interleukin-1 beta promotes functional recovery of crushed peripheral nerve.

Journal Article J Orthop Res · September 1999 Featured Publication This study was conducted to elucidate the role of the cytokine interleukin-1 beta on peripheral nerve recovery following crush injuries of two different magnitudes. Eighty-eight female rats were divided into four groups. A 5-mm segment of the right sciatic ... Full text Link to item Cite

Osteonecrosis of the femoral head associated with pregnancy. A preliminary report.

Journal Article J Bone Joint Surg Am · June 1999 Featured Publication BACKGROUND: Osteonecrosis is usually associated with trauma, use of corticosteroids, or alcohol abuse. We investigated the rare association of osteonecrosis of the femoral head and pregnancy, and we defined differences between the disorder in pregnant wome ... Full text Link to item Cite

Influences of inflation rate and duration on vasodilatory effect by intermittent pneumatic compression in distant skeletal muscle.

Journal Article J Orthop Res · May 1999 Previous study has demonstrated that application of intermittent pneumatic compression on legs can cause vasodilation in distant skeletal muscle at the microcirculation level. This study evaluated the influence of inflation rate and peak-pressure duration ... Full text Link to item Cite

Motor functional and morphological findings following end-to-side neurorrhaphy in the rat model.

Journal Article J Orthop Res · March 1999 Featured Publication Nerve repair cannot always be achieved by the conventional end-to-end technique. This study evaluated the functional recovery of nerves repaired with end-to-side neurorrhaphy in a rat model. The right peroneal nerves of 80 female rats were transected and d ... Full text Link to item Cite

Replantation

Chapter · 1999 Cite

Intermittent pneumatic compression of legs increases microcirculation in distant skeletal muscle.

Journal Article J Orthop Res · January 1999 Featured Publication Intermittent pneumatic compression has been established as a method of clinically preventing deep vein thrombosis, but the mechanism has not been documented. This study observed the effects of intermittent pneumatic compression of legs on the microcirculat ... Full text Link to item Cite

Effect of a NOS inhibitor, L-NMMA, on the contractile function of reperfused skeletal muscle.

Journal Article J Reconstr Microsurg · January 1999 Featured Publication The authors investigated the effect of NG-monomethyl-L-arginine acetate (L-NMMA), a nitric oxide synthase (NOS) inhibitor, on the contractile function of skeletal muscle following ischemia/reperfusion (I/R) injury. The extensor digitorum longus (EDL) muscl ... Full text Link to item Cite

James D. Heckman, M.D., To lead the journal

Journal Article Journal of Bone and Joint Surgery · January 1, 1999 Full text Cite

A tribute from the Board of Trustees to the Editor, Henry R. Cowell, M.D., Ph.D.

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · January 1, 1999 Link to item Cite

Evolution of the present status of orthopaedic surgery fellowships.

Journal Article J Bone Joint Surg Am · December 1998 Link to item Cite

Correspondence

Journal Article The Journal of Bone & Joint Surgery · December 1998 Full text Cite

Proximal femur fractures after free vascularized fibular grafting to the hip.

Journal Article Clin Orthop Relat Res · November 1998 The management of symptomatic femoral head osteonecrosis in young, active patients is troublesome and controversial. At the authors' institution, 707 consecutive free vascularized fibular grafts were performed for femoral head osteonecrosis between October ... Full text Link to item Cite

Recombinant human glial growth factor 2 (rhGGF2) improves functional recovery of crushed peripheral nerve (a double-blind study).

Journal Article Neurochem Int · October 1998 This in vivo double-blind study evaluated the effect of recombinant human glial growth factor 2 (rhGGF2), a Schwann cell mitogen, on the recovery of motor function of rat sciatic nerve following crush injury. Seventy three rats were divided into three grou ... Full text Link to item Cite

Survival analysis of hips treated with core decompression or vascularized fibular grafting because of avascular necrosis.

Journal Article J Bone Joint Surg Am · September 1998 Avascular necrosis of the femoral head is a multifaceted process that leads to articular incongruity and subsequent osteoarthrosis of the joint. Clinicians concur that primary treatment should focus on preservation of the natural surface of the joint; howe ... Full text Link to item Cite

Effects of S-nitroso- N-acetylcysteine on contractile function of reperfused skeletal muscle.

Journal Article Am J Physiol Regul Integr Comp Physiol · March 1, 1998 The ultimate goal of replantation and microsurgical reconstructive operations is to regain or improve impaired function of the tissue. However, the data related to the influence of NO on tissue function are limited. This study evaluated the effects of the ... Full text Link to item Cite

S-nitroso-N-acetylcysteine protects skeletal muscle against reperfusion injury.

Journal Article Microsurgery · 1998 The effects of a nitric oxide (NO) donor on microcirculation and contractile function of reperfused skeletal muscle were studied. Rat cremaster muscles underwent 5 hours of ischemia and 90 minutes of reperfusion and were divided into two groups systemicall ... Full text Link to item Cite

Effect of increased compartment pressure on the microcirculation of skeletal muscle.

Journal Article Microsurgery · 1998 To determine the changes in capillary perfusion, which occur with elevated tissue pressure, and to highlight the relationship between systemic blood pressure and compartment pressure, we designed an experiment that allowed direct observation of the microci ... Full text Link to item Cite

Revascularization of the femoral head in osteonecrosis.

Journal Article J Am Acad Orthop Surg · 1998 Osteonecrosis of the femoral head accounts for as many as 18% of total hip arthroplasties performed in western countries. The young age of affected patients and the potentially poor outcome have sparked an interest in alternative treatment modalities. Extr ... Full text Link to item Cite

Anticardiolipin antibodies and osteonecrosis of the femoral head.

Journal Article Clin Orthop Relat Res · December 1997 The current study evaluated the prevalence of anticardiolipin antibodies, which have been associated with thrombotic phenomena, in patients with nontraumatic osteonecrosis of the hip and assessed whether the presence of such antibodies is associated with a ... Link to item Cite

Elbow allograft for reconstruction of the elbow with massive bone loss. Long term results.

Journal Article Clin Orthop Relat Res · August 1997 Transplantation of total elbow allografts has been used as a salvage procedure in an attempt to provide patients with functional, painless range of motion of the elbow. This procedure is appropriate for patients with massive bone loss after trauma, tumor r ... Link to item Cite

Studies of ischemia-reperfusion injury in skeletal muscle: efficacy of 21-aminosteroids on microcirculation and muscle contraction after an extended period of warm ischemia.

Journal Article J Orthop Res · July 1997 The present study was conducted to elucidate the effects of tirilazad mesylate (U-74006F), a potent inhibitor of lipid peroxidation, on vessel diameter, capillary perfusion, and contractile function of rat cremaster muscle during a 90-minute reperfusion pe ... Full text Link to item Cite

Antithrombotic potencies of enoxaparin in microvascular surgery: influence of dose and administration methods on patency rate of crushed arterial anastomoses.

Journal Article J Hand Surg Am · May 1997 This study evaluated the influence of the dose and administration methods of enoxaparin, a low-molecular-weight heparin, on the patency rate of crushed rat femoral arteries following anastomosis. An impact crush with a 25-kg magnitude was applied to a 2-mm ... Full text Link to item Cite

Calcitonin gene-related peptide and reperfusion injury.

Journal Article J Orthop Res · March 1997 Calcitonin gene-related peptide is a potent intrinsic vasodilator, can induce prostacyclin release, and may inhibit membrane lipid peroxidation. This study examines the effect of calcitonin gene-related peptide on vessel diameters, capillary perfusion, and ... Full text Link to item Cite

Comparison of distal humerus fracture fixation: a biomechanical study.

Journal Article J South Orthop Assoc · 1997 Few biomechanical studies have been done evaluating the rigidity of internal fixation constructs for distal humerus fractures. We assessed the bending and torsional stiffness of five commonly used multiple plate constructs. Plates were applied in three pos ... Link to item Cite

Assessment of ischemia and reperfusion injury.

Journal Article Clin Orthop Relat Res · January 1997 Direct videomicroscopy of the rat cremaster muscle microcirculation supplemented by animal models of replantation, vascular crushing, and muscle function after injury and recovery were used to investigate the occurrence of reperfusion failure. It is eviden ... Link to item Cite

Digital nerve penetration by a digital artery in a patient with neurovascular symptoms: a case report.

Journal Article J Hand Surg Am · November 1996 A patient presented with neurovascular symptoms due to penetration of a proper digital nerve by a common digital artery. To knowledge, our report is the first clinically relevant description of this underrecognized, but relatively common anatomic variation ... Full text Link to item Cite

Protective effect of 21-aminosteroid pretreatment in peripheral nerve low-load crush injury in mature and immature rats.

Journal Article J Orthop Res · September 1996 The effects of U-74006F (tirilazad mesylate), a 21-aminosteroid antioxidant, on injured peripheral nerve were studied. Twenty-two immature and 44 mature rats were divided equally into two groups. The experimental group received two injections of 3 mg/kg of ... Full text Link to item Cite

Tumor necrosis factor promotes motor functional recovery in crushed peripheral nerve.

Journal Article Neurochemistry international · August 1996 The potential benefits of tumor necrosis factor pretreatment in promoting motor functional recovery of peripheral nerve following low load crush injury were examined. Using a specially designed crush device, rat sciatic nerve was subjected to a low load cr ... Full text Cite

Protective effect of hypothermia on contractile force in skeletal muscle.

Journal Article J Orthop Res · May 1996 The clinical success of limb replantation and tissue transfer is partly dependent on the duration of ischemia experienced by the amputated part. This study focused primarily on the damage that occurs during this ischemic period. An experimental system was ... Full text Link to item Cite

Complications of nonoperative and operative treatment of carpal tunnel syndrome.

Journal Article Hand Clin · May 1996 The popularity of treatment of carpal tunnel syndrome has resulted in a significant number of complications. A rational plan of therapy is available for each category of complications of carpal tunnel syndrome. This article presents 14 of the most frequent ... Link to item Cite

Donor-site morbidity with use of vascularized autogenous fibular grafts.

Journal Article J Bone Joint Surg Am · February 1996 One hundred and ninety-eight consecutive patients (247 vascularized fibular grafts) were studied to determine the prevalence of morbidity at the donor site after the grafts had been obtained. Objective motor weakness, subjective discomfort in the ankle and ... Full text Link to item Cite

Load tolerance of tibial plateau depressions reinforced with a cluster of K-wires.

Journal Article Bull Hosp Jt Dis · 1996 The efficacy of subchondral Kirschner wires in enhancing load tolerance of the tibial plateau articular cartilage was examined in a biomechanical study of cadaveric tibias. Seven patterns of K-wires were evaluated under axial loading equivalent to the maxi ... Link to item Cite

Actions of glucocorticosteroids on ischemic-reperfused muscle and cutaneous tissue.

Journal Article Microsurgery · 1996 Ischemia-reperfusion injury represents a complex series of vascular and cellular events that resembles an acute inflammatory reaction within the reperfused tissue. This article provides an overview of glucocorticosteroid effects on cells and tissues involv ... Full text Link to item Cite

Thrombosis and thrombolysis in crushed arteries with or without anastomosis: a new microvascular thrombosis model.

Journal Article J Reconstr Microsurg · January 1996 This study introduces a new rat thrombosis model in which a 2-mm segment of femoral artery is crushed by an impact load. Ninety-five femoral arteries were divided into five groups. The vessels in Groups I and 2 underwent only crush injuries with a 15-kg an ... Full text Link to item Cite

Effects of dexamethasone on the contractile function of reperfused skeletal muscle.

Journal Article Microsurgery · 1996 This study evaluated the effects of dexamethasone (DXM) on contractile function of reperfused extensor digitalis longus (EDL) muscles following 3-hour ischemia and 24-hour reperfusion. The rats were divided into four groups: normal muscle, ischemia with sa ... Full text Link to item Cite

Functional effects of lymphotoxin on crushed peripheral nerve.

Journal Article Microsurgery · 1996 The effect of lymphotoxin (LT) on the functional recovery of crushed peripheral nerves was studied. Using a specially designed compression device, a 5 mm segment of the right sciatic nerve of rats was subjected to a 100 g crush load with a 2 hr duration. T ... Full text Link to item Cite

A surgical guide for identifying the lateral femoral circumflex vessels during free vascularized fibular transfer for avascular necrosis of the femoral head.

Journal Article J Reconstr Microsurg · January 1996 Free vascularized fibular transfer for avascular necrosis of the femoral head was developed in an attempt to preserve, rather than replace, the femoral head. In this procedure, the peroneal vessels of the autogenous fibular graft are anastomosed to recipie ... Full text Link to item Cite

Results of interfascicular nerve grafting for radial nerve lesions.

Journal Article Microsurgery · 1996 During the 10 year interval 1979-1989, 20 patients underwent nerve grafting of a radial nerve lesion, 13 high radial and 7 posterior interosseous. Average follow-up was 38 months (range 12 months-10 years). Overall 72% of patients achieved a Highet Scale r ... Full text Link to item Cite

The effect of exposure time on microsurgical anastomoses of experimentally crushed arteries.

Journal Article Int Angiol · September 1995 Replantation after crushing amputation has a relatively low success rate. Although the mechanism of trauma is a major factor in failure, the time lapse before vessel anastomosis may also be a contributing factor. In this study, we observed the influence of ... Link to item Cite

Effects of cold ischemia on reflow patterns in the rat cremaster muscle microcirculation.

Journal Article Int Angiol · September 1995 In replantation and tissue transplantation an ischemic period is inevitable until blood flow is reestablished. This study evaluated the reflow patterns of the rat cremaster microcirculation after warm and cold ischemia with the use of vital microscopy. The ... Link to item Cite

Efficacy of recombinant human manganese superoxide dismutase compared to allopurinol in protection of ischemic skeletal muscle against "no-reflow".

Journal Article J Reconstr Microsurg · May 1995 A growing body of experimental data indicates that the "no-reflow" phenomenon is a type of reperfusion injury in skeletal muscle which may, in part, be mediated by oxygen free radicals, and thus may be attenuated by using agents that scavenge or inhibit fo ... Full text Link to item Cite

Pathophysiology and related studies of the no reflow phenomenon in skeletal muscle.

Journal Article Clin Orthop Relat Res · May 1995 Although the success rate of microvascular replantation and revascularization procedures has increased steadily since the 1960s, some replanted tissues do not reperfuse despite technically adequate arterial anastomoses. This failure of microvascular perfus ... Link to item Cite

Treatment of osteonecrosis of the femoral head with free vascularized fibular grafting. A long-term follow-up study of one hundred and three hips.

Journal Article J Bone Joint Surg Am · May 1995 The results for 103 consecutive hips (eighty-nine patients) that had been treated with free vascularized fibular grafting because of symptomatic osteonecrosis of the femoral head were reviewed in a prospective study. The disease was associated with consump ... Full text Link to item Cite

Outcomes in surgical treatment of femoral neck fracture: analysis of failures secondary to osteonecrosis.

Journal Article J South Orthop Assoc · 1995 We analyzed failures of surgical treatment of femoral neck fractures due to osteonecrosis in a consecutive series of 26 patients with an average age of 31 (range, 10 to 49 years). These patients were referred for treatment of osteonecrosis that developed a ... Link to item Cite

Effects of enoxaparin, standard heparin, and streptokinase on the patency of anastomoses in severely crushed arteries.

Journal Article Microsurgery · 1995 The effects of topical irrigation with three antithrombotic agents on the patency of anastomosed arteries following crush injury were examined. Following an impact crush injury with a 25 kg crush load, the femoral arteries of rats were divided and then ana ... Full text Link to item Cite

Basic principles of tendon transfers in the hand

Conference CURRENT TRENDS IN HAND SURGERY · January 1, 1995 Link to item Cite

The effect of heparin after microsurgical repair in traumatically damaged arteries.

Journal Article Int Angiol · December 1994 A main consideration of microvascular surgery is the avoidance of thrombosis. This traditionally involves the avoidance of thrombogenic trauma, the establishment of normal blood flow and full vessel diameter, as well as the use of anticoagulants, such as h ... Link to item Cite

Results after replantation and revascularization in the upper extremity in children.

Journal Article J Bone Joint Surg Am · December 1994 The rates of survival of the amputated part and the functional outcomes were studied retrospectively after seventy-three replantations and eighty-nine revascularizations in the upper extremity in 120 children. All operations were performed between January ... Full text Link to item Cite

Preservation of excellence.

Journal Article J Bone Joint Surg Am · September 1994 Full text Link to item Cite

UNTITLED - REPLY

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · September 1, 1994 Link to item Cite

UNTITLED - REPLY

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · August 1, 1994 Link to item Cite

UNTITLED - REPLY

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · August 1, 1994 Link to item Cite

UNTITLED - REPLY

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · August 1, 1994 Link to item Cite

UNTITLED - REPLY

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · August 1, 1994 Link to item Cite

Denatured muscle as a nerve conduit: a functional, morphologic, and electrophysiologic evaluation.

Journal Article J Reconstr Microsurg · May 1994 This experimental study evaluated denatured skeletal muscle and denatured epineural basement membrane tube as conduits to bridge defects in rat sciatic nerve. A 1-cm segment of sciatic nerve was resected in 48 rats. In Group I (control), the segment was di ... Full text Link to item Cite

Peripheral nerve compression.

Journal Article Instr Course Lect · 1994 Link to item Cite

Letter to the editor [2]

Journal Article Journal of Bone and Joint Surgery · January 1, 1994 Cite

Carpal tunnel release. A prospective, randomized assessment of open and endoscopic methods.

Journal Article J Bone Joint Surg Am · September 1993 To define the role of two-portal endoscopic carpal-tunnel release as a method for the treatment of compression of the median nerve at the wrist, a prospective, randomized, multicenter study was performed on 169 hands in 145 patients. Either open or endosco ... Full text Link to item Cite

The influence of magnitude and duration of crush load on functional recovery of the peripheral nerve.

Journal Article J Reconstr Microsurg · July 1993 This study investigated the effect of crush duration at different loads on motor functional recovery. One hundred and thirty-eight rats were divided into five groups: sham operation, resected sciatic nerve, and 100 g, 500 g, and 15,000 g of sciatic crush l ... Full text Link to item Cite

Niebauer trapeziometacarpal arthroplasty: a long-term follow-up.

Journal Article J Hand Surg Am · July 1993 A retrospective review of long-term follow-up of Niebauer trapeziometacarpal arthroplasty for treatment of disabling arthritis of the basal joint was performed. Thirty implants in 27 patients were reviewed, with an average follow-up of 9 years (minimum, 4 ... Full text Link to item Cite

An experimental canine model of osteonecrosis: characterization of the repair process.

Journal Article J Orthop Res · May 1993 Osteonecrosis of the femoral head was induced in dogs by a process of deep freezing, accompanied by stripping of the soft-tissue attachments from the femoral neck and intertrochanteric area, in an effort to develop an experimental model to study treatment ... Full text Link to item Cite

Microvascular anastomoses in growing vessels: a long-term evaluation of nonabsorbable suture materials.

Journal Article J Reconstr Microsurg · May 1993 Diametric growth at the anastomotic site, following microvascular anastomoses in pediatric patients, remains a problem, when nonabsorbable suture material is used. This study investigated the long-term effects of femoral artery anastomoses with nonabsorbab ... Full text Link to item Cite

Comparison of 10-0 polypropylene and 10-0 nylon sutures in rat arterial anastomosis.

Journal Article Microsurgery · 1993 The selection of suture materials is an important factor in further improving the results of microsurgical operations. In this study, two kinds of nonabsorbable suture materials, 10-0 polypropylene and 10-0 nylon monofilament, were compared in end-to-end a ... Full text Link to item Cite

Recovery following stretch injury to the sciatic nerve of the rat: an in vivo study.

Journal Article J Reconstr Microsurg · January 1993 Stretch injuries to peripheral nerves are often associated with poor recovery, which may relate to both the character and the extent of structural alterations in the nerve trunk. Previous biomechanical studies have provided insight into such structural cha ... Full text Link to item Cite

Micro-anastomosis of 0.3-0.4 mm vessels after cold ischemia using a rat model of toe-to-thumb transplantation.

Journal Article Microsurgery · 1993 Anastomoses of vessels of less than 0.5 mm in diameter remain a challenge from the technical aspect. Clinically such anastomoses are necessary for replantation of the distal digit in adults and whole digits in children. Survival data for replantation of th ... Full text Link to item Cite

Effect of denervation on endothelium-derived relaxing factor-dependent relaxation in the rat cremaster muscle.

Journal Article Microsurgery · 1993 Endothelium-derived relaxation mediated primarily by endothelium-derived relaxing factor/nitric oxide (EDRF/NO) is essential in the maintenance of vascular tone. However, little is known about the effects of denervation on EDRF-mediated relaxation in the m ... Full text Link to item Cite

Free vascularized fibula in traumatic long bone defects and in limb salvaging following tumor resection: comparative study.

Journal Article Microsurgery · 1993 In this retrospective analysis, we present our experience with two groups of patients who had long bone defects secondary to trauma or tumor resection and who were treated with a free vascularized fibular graft for skeletal reconstruction. Both groups were ... Full text Link to item Cite

Peripheral nerve compression

Journal Article Journal of Bone and Joint Surgery · January 1, 1993 Full text Cite

The effect of endothelin-1 on muscle microcirculation and its attenuation by verapamil.

Journal Article J Reconstr Microsurg · January 1993 The vascular endothelium plays an important role in the regulation of vascular tone, by producing both vasodilating and vasoconstricting mediators. Using intravital videomicroscopy, this study examined the in vivo responses of the rat cremaster muscle micr ... Full text Link to item Cite

The functional recovery of peripheral nerves following defined acute crush injuries.

Journal Article J Orthop Res · September 1992 This study evaluates the effect of crushing load on functional recovery of the sciatic nerve. Male Sprague-Dawley rats were divided into five groups: sham operation, resected sciatic nerve, and 100 g (13 mm Hg/mm2), 500 g (50 mm Hg/mm2), and 15,000 g (1,00 ... Full text Link to item Cite

Anterior capsulotomy and continuous passive motion in the treatment of post-traumatic flexion contracture of the elbow. A prospective study.

Journal Article J Bone Joint Surg Am · September 1992 Thirty-three patients who had a post-traumatic flexion contracture of the elbow were managed consecutively with anterior capsulotomy without tenotomy of the biceps tendon or myotomy of the brachialis muscle. The first fifteen patients (Group I) did not rec ... Link to item Cite

Reversing nerve-graft polarity in a rat model: the effect on function.

Journal Article J Reconstr Microsurg · July 1992 To evaluate the effect of nerve-graft polarity on function, a 1-cm segment of sciatic nerve was excised and reoriented in three groups of 20 adult Sprague-Dawley rats. In one group, the nerve was cut and anastomosed in the original orientation to act as a ... Full text Link to item Cite

Hemodynamic and histological differences in end-to-side anastomoses.

Journal Article Microsurgery · 1992 An end-to-side anastomosis is often a necessity in replantation surgery. This study examines the effects of elliptical versus slit arteriotomy and the angle of anastomosis on vessel patency and aneurysm formation. Forty male rats were divided into four gro ... Full text Link to item Cite

Combined effect of acute denervation and ischemia on the microcirculation of skeletal muscle.

Journal Article J Orthop Res · January 1992 Using direct in vivo videomicroscopy and a fluorescein dye technique, reperfusion injury after 3 h of ischemia was studied in the acutely denervated cremaster muscle of the rat. Compared with normally innervated controls, ischemia-induced reperfusion injur ... Full text Link to item Cite

Direct end-to-end repair of flexor pollicis longus tendon lacerations.

Journal Article J Hand Surg Am · January 1992 Between 1976 and 1986, 38 consecutive acute isolated flexor pollicis longus lacerations were repaired. This study excluded all replanted or mutilated digits and all lacerations with associated fracture. Average follow-up was 26 months. Tendon rehabilitatio ... Full text Link to item Cite

DIRECT END-TO-END REPAIR OF FLEXOR POLLICIS LONGUS TENDON LACERATIONS

Journal Article JOURNAL OF HAND SURGERY-AMERICAN VOLUME · January 1, 1992 Link to item Cite

Hematogenous patellar osteomyelitis associated with human immunodeficiency virus.

Journal Article Orthop Rev · September 1991 The case of a 37-year-old man with hematogenous osteomyelitis associated with the human immunodeficiency virus (HIV) is presented, with a review of the literature. Hematogenous osteomyelitis is a relatively rare entity in the patella; most cases have invol ... Link to item Cite

Prosthetic silicone scaphoid strains: effects of intercarpal fusions.

Journal Article J Hand Surg Am · May 1991 To assess stress shielding by partial intercarpal fusion, strains within a silicon scaphoid prosthesis were measured in five fresh upper extremities while the wrist was moved through a functional range of motion before and after capitate-lunate and capitat ... Full text Link to item Cite

PROSTHETIC SILICONE SCAPHOID STRAINS - EFFECTS OF INTERCARPAL FUSIONS

Journal Article JOURNAL OF HAND SURGERY-AMERICAN VOLUME · May 1, 1991 Link to item Cite

The effect of acute denervation on the microcirculation of skeletal muscle: rat cremaster model.

Journal Article J Orthop Res · March 1991 Although tissue is denervated during replantation of a severed part, tissue transfer, or muscle transplantation, there are few studies concerning the effects of acute denervation on muscle microcirculation. We have described a surgical procedure that total ... Full text Link to item Cite

Morphologic and morphometric analyses of rat femoral arteries after crush injury.

Journal Article Microsurgery · 1991 Replantation after crush amputation has a relatively low success rate. An arterial crush injury was produced in rats under a range of pressure (8.5 to 2,551 g/mm2) and durations (10 to 60 minutes). The degrees of vessel injury and thrombus formation were e ... Full text Link to item Cite

Inhibition of epinephrine-induced vasospasm with adrenoreceptor blockade in the rat cremaster muscle.

Journal Article Microsurgery · 1991 This study demonstrates that intravenous epinephrine causes arterial vasospasm, but not venous constriction, in the microcirculation of the rat cremaster muscle. This effect can be blocked by a smooth muscle relaxant such as papaverine or an alpha receptor ... Full text Link to item Cite

Replantation in children.

Journal Article Microsurgery · 1991 The authors have replanted 162 parts in 120 children over the past 15 years. The youngest patient, undergoing successful replantation, was aged 7 months, 3 weeks. Unlike an adult, any child suffering a traumatic amputation should be considered for a possib ... Full text Link to item Cite

Repair of isolated axillary nerve lesions after infraclavicular brachial plexus injuries: case reports.

Journal Article Neurosurgery · September 1990 Stretch injuries of the infraclavicular brachial plexus have a much better prognosis for spontaneous recovery than do their supraclavicular counterparts. We present three patients with stretch injuries of the infraclavicular brachial plexus who had spontan ... Full text Link to item Cite

Certificates of added qualifications in orthopedic surgery.

Journal Article Clin Orthop Relat Res · August 1990 The debate on the issue of certificates of added qualifications (CAQs) will continue since the arguments are strong in each direction. Unlike orthopedic surgery, the vast majority of medical specialties link certification with accreditation (CAQs with fell ... Link to item Cite

A comparative study of the effect of arterial and venous occlusion after various periods of ischemia.

Journal Article J Reconstr Microsurg · July 1990 The author attempted to quantify any additional tissue damage resulting from one hour of venous occlusion after controlled periods of ischemia in skeletal muscle, compared to equal time periods of ischemia. The rat quadriceps muscle was used. pH and temper ... Full text Link to item Cite

The initial examination for a Certificate of Added Qualifications in Surgery of the Hand.

Journal Article J Bone Joint Surg Am · June 1990 A total of 510 candidates took the 1989 Examination for Added Qualifications in Surgery of the Hand, including 412 diplomates of the American Board of Orthopaedic Surgery and ninety-eight diplomates of the American Board of Surgery. Most candidates reporte ... Link to item Cite

Distal rupture of the palmaris longus tendon and fascia as a cause of acute carpal tunnel syndrome.

Journal Article J Hand Surg Am · March 1990 Acute carpal tunnel syndrome is rare compared with its more chronic presentation. Previous reports in the literature have documented the most common causes. Rupture of the distal palmaris longus tendon into the palmaris fascia as a cause of an acute carpal ... Full text Link to item Cite

Vasodilator action of prostaglandin E1 on microcirculation of rat cremaster muscle.

Journal Article Microsurgery · 1990 Vascular spasm is often present after microsurgical procedures, and its presence or absence can greatly influence the success rate of such operations. Prostaglandin E1 (PGE1) is known to be a potent vasodilator and antiaggregator of small blood vessels. Us ... Full text Link to item Cite

Posterior labral tear as a block to reduction in an anterior hip dislocation.

Journal Article J Orthop Trauma · 1990 The patient presented with an anterior dislocation of the hip that could not be centrically reduced by closed methods. Computed tomographic imaging after trial reduction revealed a posterior fragment that was limiting reduction. At the time of open reducti ... Full text Link to item Cite

The relationship of functional return to varying methods of nerve repair.

Journal Article J Reconstr Microsurg · January 1990 This experimental study correlated varying methods of nerve repair with the degree of functional return using the rat sciatic nerve as a model. Six groups of adult male Sprague-Dawley rats (300 to 350 g) had their left sciatic nerve crushed (Group 1), tran ... Full text Link to item Cite

One hundred eleven thumb amputations: replantation vs revision.

Journal Article Microsurgery · 1990 One hundred eleven patients who sustained isolated, complete thumb amputation between 1971 and 1985 were reviewed to assess results of replantation and to compare these with results of amputation revision. Routine postoperative evaluation was performed in ... Full text Link to item Cite

Management of severe musculoskeletal injuries of the upper extremity.

Journal Article J Orthop Trauma · 1990 Limb salvage was successful in 25 patients treated for severe grade III upper extremity injuries. In a retrospective review of 20 men and five women, follow-up time averaged 26 months. These high-energy injuries were characterized by massive soft-tissue in ... Link to item Cite

Nerve transposition for the restoration of elbow flexion following brachial plexus avulsion injuries.

Journal Article J Neurosurg · January 1990 Despite technical advances, the ability to restore motor function following a brachial plexus avulsion is limited. Twenty patients who suffered the loss of elbow flexion following a brachial plexus avulsion injury underwent a neurotization procedure in an ... Full text Link to item Cite

Effects of vascularized bone graft on surrounding necrotic bone: An experimental study. Invited discussion I

Journal Article Journal of Reconstructive Microsurgery · January 1, 1990 Cite

Effect of ischemia on microcirculation thrombosis in skeletal muscle

Journal Article Surgical Forum · December 1, 1989 Cite

Silicone synovitis: clinical, radiologic, and histologic features.

Journal Article South Med J · September 1989 We have described a patient in whom an erosive arthropathy of the right wrist developed three years after insertion of a silicone lunate prosthesis. The clinical picture of silicone synovitis is being recognized more frequently after bone and joint implant ... Link to item Cite

Diagnosis of ganglion in Guyon's canal by magnetic resonance imaging.

Journal Article J Hand Surg Am · July 1989 Compression of the ulnar nerve at the wrist can be caused by a multitude of intrinsic and extrinsic factors. The exact diagnosis and location of compression can frequently be difficult to determine. Magnetic resonance imaging can be a useful method in diag ... Full text Link to item Cite

Use of the anterior branch of the medial antebrachial cutaneous nerve as a graft for the repair of defects of the digital nerve.

Journal Article J Bone Joint Surg Am · April 1989 Using the anterior branch of the medial antebrachial cutaneous nerve, grafting was performed on twenty-one digital nerves. The goal of the procedure was to repair a traumatic defect of greater than one centimeter in the digital nerves of fourteen patients. ... Link to item Cite

Digital replantation at the level of the distal interphalangeal joint and the distal phalanx.

Journal Article J Hand Surg Am · March 1989 Forty-two complete, single digit amputations at the level of the distal interphalangeal joint or distal phalanx are reviewed. Viability was 81%. Operative time averaged 4.6 hours. Average age of patients was 28 years and 90% were male. Forty-eight percent ... Full text Link to item Cite

Management of Severe Musculoskeletal Injuries of the Upper Extremity

Journal Article Journal of Bone and Joint Surgery, American Volume · 1989 Cite

Indications for replantation in the adult upper extremity.

Journal Article Occup Med · 1989 Physicians involved in the evaluation and initial treatment of patients with severe hand injuries should be familiar with the indicators for, the contraindications to, and expectations following replantation, including preoperative preservation of the ampu ... Link to item Cite

Laser Doppler monitoring of replants using a small prism probe.

Journal Article Microsurgery · 1989 Eighteen patients admitted to Duke University Medical Center for upper limb replantation or revascularization were studied. A small laser Doppler flow prism probe and a cutaneous temperature probe were attached to the distal pulp of replanted digits. Measu ... Full text Link to item Cite

Microcirculatory responses to vascular washout following ischemia.

Journal Article Microsurgery · 1989 This study examined the microcirculatory alterations in the hindlimb of the rat caused by ischemia and vascular washout with lactated Ringer's solution. Experimental groups consisted of innervated and denervated animals, each subjected to 2 hours of hindli ... Full text Link to item Cite

Intravascular thrombosis in skeletal muscle microcirculation after ischemia.

Journal Article Microsurgery · 1989 This study was undertaken to elucidate the role of thrombosis in blood vessels less than 0.1 mm in diameter in skeletal muscle after an ischemic episode. Capillaries were examined after normothermic ischemia using intravital video microscopy of the cremast ... Full text Link to item Cite

RAILROAD RELATED INJURIES - THEIR ORTHOPEDIC EVALUATION, MANAGEMENT, AND OUTCOME

Journal Article SOUTHERN MEDICAL JOURNAL · September 1, 1988 Link to item Cite

MAGNETIC-RESONANCE IMAGING IN THE WORKUP OF THE PAINFUL WRIST

Journal Article SOUTHERN MEDICAL JOURNAL · September 1, 1988 Link to item Cite

An improved method of recording rat tracks for measurement of the sciatic functional index of de Medinaceli.

Journal Article J Neurosci Methods · July 1988 The use of paper impregnated with Bromphenol blue for recording normal rat footprints is described. Because paper provides a better grip than X-ray film for the paws of the rats, the resulting tracks make manual scoring easier and more accurate. In additio ... Full text Link to item Cite

Plantar Fibromatosis

Chapter · 1988 Cite

Treatment of Aseptic Necrosis of the Femoral Head by Free Vascularized Fibular Graft

Journal Article Journal of Bone and Joint Surgery, American Volume · 1988 Cite

Management of Severe Musculoskeletal Injuries of the Upper Extremity

Journal Article Journal of Bone and Joint Surgery, American Volume · 1988 Cite

Inhibition of vessel allograft rejection by endothelial removal. Morphologic and ultrastructural changes.

Journal Article Ann Surg · December 1987 The vascular endothelium plays an important and complex role in vascular allograft rejection. Antigens expressed by the endothelium can act to promote and be the target of rejection reactions, which often lead to thrombosis and ischemic necrosis of the all ... Full text Link to item Cite

Use of the surgical glove in microsurgery.

Journal Article J Reconstr Microsurg · October 1987 The disposable surgical glove can serve as a model for toe-to-hand transfer, as a template for flap design, and as a ring tourniquet for the finger. The low cost, effectiveness, and easy handling of the glove warrant its role in reconstructive microsurgery ... Full text Link to item Cite

Effect of irrigation fluids on arterial and venous endothelium after ischemia.

Journal Article J Reconstr Microsurg · October 1987 This study examines the extent of endothelial damage following a period of irrigation with various crystalloid irrigation fluids. Both arteries and veins were evaluated after irrigation with normal saline, lactated Ringer's, Balanced Salt Solution (BSS), a ... Full text Link to item Cite

Demographics and replantation.

Journal Article J Hand Surg Am · September 1987 We reviewed demographic data on 761 patients who had one or more amputated parts replanted at Duke University Medical Center between 1972 and 1984 to learn more about the population that sustained amputation and replantation. Ninety-four percent were from ... Full text Link to item Cite

Clinical use of bone allografts in the elbow.

Journal Article Orthop Clin North Am · April 1987 Transplantation of total or partial elbow allografts has been performed in 12 patients with excessive bone loss secondary to trauma or tumor resection. Nine of 12 implants remain with a 2- to 9-year follow-up. Functional, painless elbow motion is present i ... Link to item Cite

Variance of radial growth in vascularized and nonvascularized free bone grafts including epiphysis in puppies.

Journal Article J Reconstr Microsurg · April 1987 A portion of radius including the proximal epiphysis was either transplanted or excised and replaced in puppies. In these growing animals, growth in long bone grafts vascularized by periosteal and endosteal vessels but not epiphyseal vessels, was significa ... Full text Link to item Cite

The microsurgical triple clamp: a technique for microvascular grafting of short interposition grafts.

Journal Article J Reconstr Microsurg · April 1987 The microsurgical triple clamp has been developed for use when grafting arteries and veins. Advantages are that the grafting technique can be performed by one person, that the clamp anchors the graft so that quick yet accurate anastomoses can be performed, ... Full text Link to item Cite

Forearm force transmission after surgical treatment of distal radioulnar joint disorders.

Journal Article J Hand Surg Am · March 1987 To evaluate the effect of silicone replacement of the distal ulnar, hemiresection arthroplasty and the Darrach procedure on ulnar support of the carpus, changes in force transmission to the radius and ulnar were measured using load cells in axially loaded ... Full text Link to item Cite

Longitudinal epiphyseal growth after replantation and transplantation in children.

Journal Article J Hand Surg Am · March 1987 Previous investigators have shown that epiphyses are unlikely to grow after free grafting although there have been rare reports of good and even normal growth. However, growth has usually continued whenever the epiphyseal vascular supply has been maintaine ... Full text Link to item Cite

Arterial stump pressure: a determinant of arterial patency?

Journal Article J Hand Surg Am · March 1987 Twenty-seven patients with acute injuries to the radial or ulnar arteries had arterial repairs using microvascular techniques. No patient had an ischemic hand secondary to his arterial injury. The overall patency rate for all repaired vessels was 56%. For ... Full text Link to item Cite

An alternative technique of microvascular anastomosis.

Journal Article Microsurgery · 1987 The femoral arteries and veins of rats were severed and reanastomosed, using either the conventional interrupted suture technique or an alternative interrupted technique that allows the lumen to remain visible throughout the reanastomosis procedure. The al ... Full text Link to item Cite

Injury to the brachial plexus during Putti-Platt and Bristow procedures. A report of eight cases.

Journal Article Am J Sports Med · 1987 Eight patients with documented recurrent anterior dislocation of the shoulder sustained iatrogenic brachial plexus injuries during either Putti-Platt or Bristow procedures. Two patients also sustained axillary artery injuries. There were six males and two ... Full text Link to item Cite

Relief of blood-induced arterial vasospasm by pharmacologic solutions.

Journal Article J Reconstr Microsurg · January 1987 A partially amputated rat hind limb model was used to evaluate the potency of 1 percent, 2 percent, and 20 percent Xylocaine, 0.3 percent papaverine, and normal saline in both the treatment and prevention of blood-induced arterial spasm. Direct application ... Full text Link to item Cite

Patency after repair of forearm arterial injuries in animal models.

Journal Article J Hand Surg Am · January 1987 Repairs of single artery forearm injuries have only a 50% patency rate. The single artery repairs in the forelimbs of the 10 dogs and 42 rabbits studied in this investigation also had patency rates of approximately 50%. The collateral arteries appeared to ... Full text Link to item Cite

The wraparound procedure for thumb and finger reconstruction.

Journal Article Microsurgery · 1987 Nineteen thumb and finger reconstructions were performed using the wraparound procedure; there were five early arterial failures. Thirteen of the 14 successful digital reconstructions were reviewed at an average of 26 months after surgery. There were compl ... Full text Link to item Cite

Skeletal fixation in digital replantation. Use of the "H" plate.

Journal Article Clin Orthop Relat Res · January 1987 Many forms of bone fixation have been advocated for use in digital replantation, and successful series have been reported using such methods as intramedullary Kirschner-wire fixation, crossed Kirschner-wires, bone pegs, double-headed screws, and bone plate ... Link to item Cite

Blood-induced arterial segmental spasm.

Journal Article J Reconstr Microsurg · October 1986 Blood-induced arterial segmental spasm has been noticed clinically, and is thought to result from contact between a main feeding artery and extravasating blood from one of its side branches. This localized spasm can persist long enough to compromise the su ... Full text Link to item Cite

Peripheral nerve grafts: the relationship of axonal growth cone and biomechanical properties.

Journal Article J Hand Surg Am · March 1986 Cat sciatic nerves containing 2 and 4 cm nerve grafts were subjected to tensile testing with the finding that a significant decrease in force at failure occurs at the distal suture line at a time after surgery that is graft length dependent. Tritiated labe ... Full text Link to item Cite

PERIPHERAL-NERVE GRAFTS - THE RELATIONSHIP OF AXONAL GROWTH CONE AND BIOMECHANICAL PROPERTIES

Journal Article JOURNAL OF HAND SURGERY-AMERICAN VOLUME · March 1, 1986 Link to item Cite

The surgical and rehabilitation management of vascular injury to the hand.

Journal Article Hand Clin · February 1986 To be truly successful, a revascularized or replanted hand must not only survive but also function. Survival can be achieved by microvascular surgery, but function depends on integration between the initial surgery and subsequent rehabilitation. In this co ... Link to item Cite

Management of Severe Open Extremity Fractures

Journal Article Journal of Bone and Joint Surgery, American Volume · 1986 Cite

Management of Severe Open Extremity Injuries

Journal Article Journal of Bone and Joint Surgery, American Volume · 1986 Cite

Avascular Necrosis of the Femoral Head Treated by Vascularized Fibular Graft.

Journal Article Journal of Bone and Joint Surgery, American Volume · 1986 Cite

Canine experimental free muscle transplantation.

Journal Article Microsurgery · 1986 Transplants of the cranial portion of the dog sartorius muscle were able to generate 70% of control force after 3 months if the artery, vein, and nerve were reanastomosed. Our histological and histochemical findings correlate with the functional findings. ... Full text Link to item Cite

Intimal tears and their relationship to long-term patency in the rat femoral artery.

Journal Article Microsurgery · 1986 The prognostic importance of arterial intimal tears is not certain in the long term. We have developed a model to evaluate pure intimal damage in the absence of other soft tissue injury or arterial anastomoses to study the effect of isolated traumatic arte ... Full text Link to item Cite

A comparison of absorbable and nonabsorbable sutures to vascular response in immature arteries.

Journal Article J Reconstr Microsurg · January 1986 Absorbable suture material for microvascular procedures may be superior to nonabsorbable sutures because no foreign body remains at the operative site after suture absorption. We compared Vicryl (polyglactin 910) to a nonabsorbable suture, Prolene, which h ... Full text Link to item Cite

Ulnar artery thrombosis: a sports-related injury.

Journal Article Am J Sports Med · 1986 A case of ulnar artery thrombosis following a sports-related injury is reported. Treatment by resection of the thrombosed segment and replacement with a reversed vein graft resulted in complete relief of symptoms. An extensive review of the literature is p ... Full text Link to item Cite

A biomechanical comparison of the methods for treating Kienböck's disease.

Journal Article J Hand Surg Am · January 1986 Reduction of lunate compression is thought to promote revascularization of the lunate in patients with Kienböck's disease. The decompressing abilities of ulnar lengthening, radial shortening, capitate-hamate fusion, and scaphoid-trapezium-trapezoid (STT) f ... Full text Link to item Cite

Role of thromboxane in postischemic microcirculatory blood flow

Journal Article Surgical Forum · January 1, 1986 Cite

CADAVERIC ELBOW ALLOGRAFTS - AN 8-YEAR EXPERIENCE

Journal Article JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME · January 1, 1986 Link to item Cite

21 SEVERE OPEN TIBIAL FRACTURES TREATED BY FREE TISSUE TRANSFER

Journal Article JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME · January 1, 1986 Link to item Cite

A 13-YEAR EXPERIENCE WITH 1000 REPLANTATIONS

Journal Article JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME · January 1, 1986 Link to item Cite

THE SURGICAL-TREATMENT OF ELBOW FLEXION CONTRACTURE

Journal Article JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME · January 1, 1986 Link to item Cite

TREATMENT OF AVASCULAR NECROSIS OF THE FEMORAL-HEAD WITH A VASCULARIZED FIBULAR GRAFT

Journal Article JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME · January 1, 1986 Link to item Cite

Osteocutaneous flaps for thumb and digit reconstruction. In unique situations.

Journal Article Hand Clin · November 1985 Osteocutaneous flaps from the foot are being utilized more for thumb and digit reconstruction. We have presented a few unique situations in which these flaps are beneficial. Not all patients with deformities similar to those described in this presentation ... Link to item Cite

Correction of post-traumatic flexion contracture of the elbow by anterior capsulotomy.

Journal Article J Bone Joint Surg Am · October 1985 Despite prolonged conservative therapy, including splinting, bracing, and supervised exercise programs, significant flexion contracture of the elbow after local trauma may remain both a functional and a cosmetic impairment. We studied the cases of fifteen ... Link to item Cite

Arterial intimal damage in avulsion and crush injuries in rat limbs.

Journal Article J Reconstr Microsurg · July 1985 A stereotypical pattern of arterial intimal damage has been demonstrated in rat avulsed and crushed injuries. These intimal tears can be found up to 6 cm proximal to the site of injury in avulsion injuries and are found at a delayed time with crush injurie ... Full text Link to item Cite

Wrap-around procedure for thumb reconstruction.

Journal Article Hand Clin · May 1985 The wrap-around procedure provides length, stability, and adequate sensibility for a functional pinch and grasp and also preserves the great toe. The procedure esthetically simulates the normal thumb and is relatively reliable when performed by a surgeon w ... Link to item Cite

Ulnar artery thrombosis.

Journal Article Hand Clin · May 1985 Management of ulnar artery thrombosis is a complex problem. Diagnosis is confirmed by Allen testing; other special studies are needed for adequate evaluation of circulation, and arteriography is necessary before definitive therapy can be planned. Treatment ... Link to item Cite

Thumb reconstruction by the wrap-around method.

Journal Article Clin Orthop Relat Res · May 1985 Reconstruction of a thumb amputated distal to the metacarpophalangeal joint can be accomplished by the "wrap-around" procedure. The operative procedure calls for an iliac crest graft to replace the bone of the amputated thumb. A flap from the great toe wit ... Link to item Cite

The results of replantation after amputation of a single finger.

Journal Article J Bone Joint Surg Am · April 1985 We reviewed fifty-nine consecutive cases of patients who had replantation of a single finger (excluding the thumb) after traumatic amputation, with an average follow-up of fifty-three months. Fifty-one (86 per cent) of the replanted fingers survived. Survi ... Link to item Cite

Repair of the flexor pollicis longus.

Journal Article Hand Clin · February 1985 There are more repair techniques available for an injured flexor pollicis longus than for the other digital flexors. The procedure of choice is immediate primary or early delayed repair (less than three weeks after injury) by direct end-to-end suture. Good ... Link to item Cite

Chemically induced vasospasm: the effect of ischemia, vessel occlusion, and adrenergic blockade.

Journal Article Plast Reconstr Surg · February 1985 Vasospasm in revascularized tissue can compromise tissue perfusion even though the microsurgical anastomoses remain patent. Circulating catecholamine stimulates peripheral vasoconstriction. Chemical vasospasm was induced by the intraarterial administration ... Full text Link to item Cite

Digital Replantation at the Level of the DIP joint and Distal Phalanx

Journal Article Journal of Bone and Joint Surgery, American Volume · 1985 Cite

Twenty-One Severe Open Tibial Fractures Treated by Free Tissue Transfer

Journal Article Journal of Bone and Joint Surgery, American Volume · 1985 Cite

Debridement and replantation of the spleen with microsurgical restoration of blood flow.

Journal Article Microsurgery · 1985 Splenectomy continues to be the most commonly chosen method of management of traumatic injury to the spleen. However, patients of all age groups who have undergone splenectomy have significant impairment of immune functions as demonstrated by decreased pro ... Full text Link to item Cite

Diaphyseal lengthening for shortness of the toe.

Journal Article Foot Ankle · 1985 A method of bone lengthening for bilateral shortness of the fourth toe in a 23-year-old woman is described. The symptomatic short fourth toes were successfully treated by metatarsal and phalangeal diaphyseal lengthenings with metatarsophalangeal joint pres ... Full text Link to item Cite

Cadaveric elbow allografts. A six-year experience.

Journal Article Clin Orthop Relat Res · 1985 Transplantation of total elbow allografts has been employed as a salvage procedure in an attempt to provide patients with a useful, painless range of motion of the elbow. Patients who are candidates for this procedure include those with disabling elbow joi ... Link to item Cite

Efficacy of crystalloid solutions as vein storage media

Journal Article Surgical Forum · January 1, 1985 Cite

THE RESULTS OF REPLANTATION AFTER AMPUTATION OF A SINGLE FINGER

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · 1985 Full text Cite

Factors contributing to aneurysm formation in rat microvascular anastomoses

Journal Article Surgical Forum · January 1, 1985 Although aneurysms form in 50% of rat microarterial anastomoses, no studies have been undertaken to determine the precise mechanism of aneurysm formation. This study examined the etiology of aneurysm formation in microarterial anastomoses by defining the c ... Cite

SINGLE FINGER REPLANTATION

Journal Article JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME · January 1, 1985 Link to item Cite

CORRECTION OF POST-TRAUMATIC FLEXION CONTRACTURE OF THE ELBOW BY ANTERIOR CAPSULOTOMY

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · 1985 Full text Cite

THE RESULT OF FREE TISSUE TRANSFER IN THE MANAGEMENT OF LOWER-EXTREMITY TRAUMA

Journal Article JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME · January 1, 1985 Link to item Cite

Spontaneous retrocarpal radial artery thrombosis: a report of two cases.

Journal Article J Hand Surg Am · November 1984 Two patients with spontaneous retrocarpal radial artery thrombosis are reported. Both patients had numbness and cold intolerance of the thumb and index finger and one patient had splinter hemorrhages. Angiography revealed identical occlusions of the radial ... Full text Link to item Cite

Microanastomotic response to needle and suture size.

Journal Article J Reconstr Microsurg · October 1984 This study was performed to examine the microanastomotic response to needle and suture size, comparing the 10-0 (75 mu needle/22 mu suture), the 11-0 (50 mu needle/18 mu suture), and a new modified 11-0 which has a 30 mu needle and a 14 mu suture. Each art ... Full text Link to item Cite

Recovery of skeletal muscle after laceration and repair.

Journal Article J Hand Surg Am · September 1984 Few data are available regarding structural and functional recovery of lacerated skeletal muscle after repair. This study used the extensor digitorum longus muscle of rabbits to document recovery after laceration and repair and a healing period of 12 weeks ... Full text Link to item Cite

Comparison of suture ligation, bipolar cauterization, and hemoclip ligation in the management of small branching vessels in a rat model.

Journal Article J Reconstr Microsurg · July 1984 In elective microsurgical procedures, it is necessary to occlude small branches when mobilizing vessels in obtaining vein grafts. The purpose of this study was to evaluate the relative merits of suture ligation, bipolar cauterization, and hemoclip ligation ... Full text Link to item Cite

Conjoined flexor and extensor pollicis longus tendons in the hypoplastic thumb.

Journal Article J Hand Surg Am · May 1984 A congenital anomalous band between the flexor pollicis longus and extensor pollicis longus tendons is, according to the literature, a rare condition. This anomalous junctura was recognized in three children with congenital thumb hypoplasia. Improved thumb ... Full text Link to item Cite

Isolated cold stress testing in the assessment of symptoms in the upper extremity: preliminary communication.

Journal Article J Hand Surg Am · May 1984 Isolated cold stress testing is introduced as a method for quantification of thermoregulatory capacity of the upper extremities. Ninety-six patients with pain, numbness, or cold intolerance were studied. All diagnoses were confirmed by operation, arteriogr ... Full text Link to item Cite

Thumb reconstruction by microsurgery.

Journal Article Instr Course Lect · 1984 A variety of vascularized toe tissue transfers are available for reconstruction of the thumb. These procedures may provide length, stability, and motion for pinch and grasp, offer adequate sensibility (average two-point discrimination is 15 mm) for prehens ... Link to item Cite

Vascular response to absorbable sutures in immature arteries

Journal Article Surgical Forum · January 1, 1984 Cite

The vascular anatomy and dissection of the free scapular flap

Journal Article Plastic and Reconstructive Surgery · January 1, 1984 Full text Cite

Dynamic radionuclide imaging as a means of evaluating vascular perfusion of the upper extremity: a preliminary report.

Journal Article J Hand Surg Am · July 1983 Vascular competence in the upper extremities of 44 patients was evaluated by three-phase bone scans consisting of rapid sequence dynamic radionuclide imaging (DRI), an immediate postinjection "blood pool" image, and a 3- to 4-hour delayed image. Findings w ... Full text Link to item Cite

Replantation in the Upper Extremity

Journal Article Orthopaedic Surgery Update Series · 1983 Cite

Should a Single Amputated Finger Be Replanted?

Journal Article Journal of Bone and Joint Surgery, American Volume · 1983 Cite

A Ten Year Experience with Replantation of Amputated Extremities

Journal Article Journal of Bone and Joint Surgery, American Volume · 1983 Cite

Storage of amputated parts prior to replantation--an experimental study with rabbit ears.

Journal Article J Hand Surg Am · January 1983 Forty mature rabbit ears were completely amputated and stored by different methods for 24 hours and then replanted. This study suggests that there is no significant difference among conventional methods of storage as long as the part is not frozen or allow ... Full text Link to item Cite

Office diagnosis and treatment of hand pain.

Journal Article Orthop Clin North Am · July 1982 Link to item Cite

The vascularized cutaneous scapular flap.

Journal Article Plast Reconstr Surg · May 1982 Five cases of cutaneous free tissue transfer using the cutaneous and circumflex scapular vessels are presented. The free scapular flap is an excellent choice when intermediate-sized (6 to 10 by 10 to 16 cm) uninnervated flap coverage is necessary and canno ... Full text Link to item Cite

Fascicular nerve suture.

Journal Article Clin Orthop Relat Res · March 1982 Fascicular and group fascicular repairs have limited application. Standard epineurial repair is suggested for most severed peripheral nerves. However, fascicular and group fascicular repairs are beneficial and even preferred in certain types of nerve injur ... Link to item Cite

The results of radial and ulnar arterial repair in the forearm. Experience in three medical centers.

Journal Article J Bone Joint Surg Am · March 1982 Sixty-two patients with ninety injuries to the radial or the ulnar artery, or to both of these arteries, had arterial repairs using microvascular techniques in three medical centers. Twenty-six of the twenty-eight patients who had an ischemic hand secondar ... Link to item Cite

The Free Vascularized Scapular Flap. Ortho. Transactions.

Journal Article Journal of Bone and Joint Surgery, American Volume · 1982 Cite

Free flap coverage of deep tissue defects of the foot.

Journal Article Foot Ankle · 1982 This is a review of seven cutaneous or myocutaneous free flaps performed at the Duke University Medical Center for coverage of foot defects. The average follow-up is 19.3 months. The average anesthetic time was 7 h and 45 min. The average length of hospita ... Full text Link to item Cite

The strength of microvascular anastomoses--an experimental evaluation in rats.

Journal Article J Microsurg · 1982 To determine the longitudinal strength of microvascular anastomoses during early healing, the left femoral arteries of 56 rats were divided and anastomosed with six interrupted sutures of 10-0 nylon. The right femoral arteries served as unoperated controls ... Full text Link to item Cite

The results of radial and ulnar arterial repair in the forearm

Journal Article Journal of Bone and Joint Surgery - Series A · January 1, 1982 Sixty-two patients with ninety injuries to the radial or the ulnar artery, or to both of these arteries, had arterial repairs using microvascular techniques in three medical centers. Twenty-six of the twenty-eight patients who had an ischemic hand secondar ... Full text Cite

SURGICAL-MANAGEMENT OF SMALL BRANCHING VESSELS

Journal Article SURGICAL FORUM · January 1, 1982 Link to item Cite

A 10 YEAR EXPERIENCE WITH REPLANTATION OF AMPUTATED HANDS AND DIGITS

Journal Article JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME · January 1, 1982 Link to item Cite

Chronic boutonniere deformity--an anatomic reconstruction.

Journal Article J Hand Surg Am · July 1981 Restoration of motion and appearance of the chronic boutonniere deformity is often accomplished by splinting. If the deformity persists following appropriate splinting, and if a full passive range of motion of the proximal interphalangeal joint is present, ... Full text Link to item Cite

Arterial shunting as an adjunct to major limb revascularization.

Journal Article Ann Surg · March 1981 Temporary arterial and venous shunting has been employed to reduce warm ischemia in major limb replantation and revascularization on eight occasions. This has allowed identification of vital structures, thorough debridement, and rigid internal or external ... Full text Link to item Cite

Coagulation changes in elective surgery and trauma.

Journal Article Ann Surg · February 1981 Although antithrombin-3 (AT-3), a naturally-occurring inhibitor of thrombin, has been associated with a variety of thrombotic disorders, it has been studied in surgery and trauma. Three groups of patients were studied: Group I (20 patients) who underwent e ... Full text Link to item Cite

Microvascular management of ring avulsion injuries.

Journal Article J Hand Surg Am · January 1981 Microsurgical revascularization has proved to be a useful method in managing the ring avulsion injury where both neurovascular bundles are damaged with only partial skin avulsion. Representative cases are used to illustrate guidelines for a practical class ... Full text Link to item Cite

Ulnar artery insufficiency: a guide to treatment.

Journal Article J Hand Surg Am · January 1981 Based o the results of treatment of 28 patients with proved ulnar artery thrombosis, multiple therapeutic regimens, including intra-arterial medications, excision and ligation of the involved segment, environmental modification and biofeedback, sympathecto ... Full text Link to item Cite

The effect of systemic acidosis on perfusion of replanted extremities.

Journal Article J Hand Surg Am · September 1980 By measuring skin temperature and muscle pH of replanted rat legs, we found that uncorrected systemic acidosis had a detrimental effect on perfusion of the replanted extremity. Following administration of systemic sodium bicarbonate and correction of acido ... Full text Link to item Cite

Use of the tourniquet during surgery in patients with sickle cell hemoglobinopathies.

Journal Article Clin Orthop Relat Res · September 1980 Twenty-one patients carrying the sickle cell gene underwent 29 operative procedures using tourniquet-induced ischemia. No statistically increased incidence of complications occurred in the sickle cell group when compared with a control group of black patie ... Link to item Cite

Boutonnière deformity: a surgical corrective procedure.

Journal Article Aust N Z J Surg · June 1980 A surgical procedure for the correction of chronic boutonnière deformity has been described. In essence, it is an anatomical reconstruction of the damaged extensor mechanism, and the procedure has proved to be a reliable method of improving both cosmetic d ... Full text Link to item Cite

Treatment of chronic orthopedic pain with zomepirac

Journal Article Journal of Clinical Pharmacology · January 1, 1980 Cite

TREATMENT OF CHRONIC ORTHOPEDIC PAIN WITH ZOMEPIRAC

Journal Article JOURNAL OF CLINICAL PHARMACOLOGY · January 1, 1980 Link to item Cite

EFFECT OF HYPOVOLEMIA ON PERFUSION AFTER DIGIT REPLANTATION

Journal Article SURGICAL FORUM · January 1, 1980 Link to item Cite

STRENGTH OF MICRO-VASCULAR ANASTOMOSES IN RAT FEMORAL ARTERIES

Journal Article SURGICAL FORUM · January 1, 1980 Link to item Cite

Microvascular surgery.

Journal Article South Med J · September 1979 Full text Link to item Cite

Temperature monitoring in digital replantation.

Journal Article J Hand Surg Am · July 1978 Postoperative monitoring of replanted and revascularized digits with skin temperature probes was performed on the 20 patients admitted to the Duke University Medical Center Orthopaedic Replantation Service from April to July, 1977. Using multiple probes, t ... Full text Link to item Cite

Digital sensibility following replantation.

Journal Article J Hand Surg Am · July 1978 The amputated digit serves as an excellent model for the examination of digital nerve repair. When amputation is complete, there is no question of cross-over or anomalous innervation. The sensibility of 35 replanted digits in 29 patients was evaluated. Sen ... Full text Link to item Cite

Management of bone in digital replantation: free vascularized and composite bone grafts.

Journal Article Clin Orthop Relat Res · June 1978 Microvascular surgical techniques have been applied to the problem of digital amputation, persistent nonunion and complicated extremity injuries with segmental bone and soft tissue loss. In replantations, adequate bone shortening and fixation with intramed ... Link to item Cite

Indication, technique and results of nerve grafting

Journal Article Handchirurgie · January 1, 1978 This is a symposion report on the possibilities and problems in nerve grafting. It is presented in discussion form. ... Cite

Metacarpophalangeal joint arthroplasty with silicone-Dacron prostheses (Niebauer type): six and a half years' experience.

Journal Article J Hand Surg Am · May 1977 Four hundred and forty-one silicone-Dacron arthroplasties done since 1968 were reviewed. Results were influenced by both durability and immediate fixation of the prosthesis, disease characteristics, speed of progression, the amount of hand stress, the exte ... Full text Link to item Cite

Experimental evaluation of microsurgical techniques in small artery anastomoses.

Journal Article Orthop Clin North Am · April 1977 A number of factors that influence the success of microvascular anastomosis have been studied, including adventitial stripping, choice of suture material and needles, suturing technique, and perfusion of the distal lumen. It is apparent that only minimal s ... Link to item Cite

Digital replantation.

Journal Article J Hand Surg Am · January 1977 Full text Link to item Cite

ILIAC APOPHYSIS - REPLY

Journal Article CLINICAL ORTHOPAEDICS AND RELATED RESEARCH · January 1, 1977 Link to item Cite

Intramedullary lipoma of the distal femur.

Journal Article South Med J · September 1976 A rare case of intramedullary lipoma involving the distal femur is presented and discussed in relation to previously reported cases. The 26 previously reported extracranial cases of this bone lesion are briefly reviewed. Emphasis is placed upon establishin ... Full text Link to item Cite

Iliac apophyses. Prognostic value in idiopathic schliosis.

Journal Article Clin Orthop Relat Res · May 1976 Fusion of the iliac apophyses with the crests of the ilium is of greater prognostic value than completion of excursion of the iliac apophyses. Completion of fusion of the vertebral ring apophyses coincides with fusion of the iliac apophyses to the crests. ... Link to item Cite

Basic anatomy and biomechanics of the low back in relation to low back pain

Journal Article ATHLETIC TRAIN. · January 1, 1976 The lumbar spine is a remarkable anatomic structure since it can withstand tremendous stresses while possessing great flexibility. Since the lumbar discs undergo the natural process of degeneration before the age of thirty, the low back is very susceptible ... Cite

Replantation of amputated digits and hands in children

Journal Article Inter Clinic Information Bulletin · January 1, 1975 This study presents our experience with replantation of amputated digits or hands in 11 children. Although in young children the blood vessels are quite small, successful vessel anastomosis can be achieved. Our present feeling is that replantation of the t ... Cite

Tendon suturing methods : analysis of tensile strengths

Journal Article American Academy of Orthopaedic Surgeons, Symposium on Tendon Surgery in the Hand · 1975 Cite

MANAGEMENT OF METASTATIC BONE TUMORS FROM ADENOCARCINOMA OF KIDNEY

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · January 1, 1975 Link to item Cite

SICKLE-CELL DISEASE AND TOURNIQUET - IS THERE A RISK

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · January 1, 1975 Link to item Cite

EVALUATION OF MICROSURGICAL TECHNIQUES IN SMALL ARTERY ANASTOMOSIS

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · January 1, 1975 Link to item Cite

REPLANTATION OF AMPUTATED DIGITS AND HANDS

Journal Article JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME · January 1, 1975 Link to item Cite

Prosthetic arthroplasty of the hand.

Journal Article Clin Orthop Relat Res · October 1974 Full text Link to item Cite

Congenital pseudarthrosis of the clavicle: a case presentation and review of the literature

Journal Article Inter Clinic Information Bulletin · January 1, 1974 Congenital pseudarthrosis of the clavicle is rare. The anomaly usually occurs in the right clavicle and is manifested by a painless and cosmetically unappealing mass. The greater the motion at the pseudarthrosis, the greater is the cosmetic deformity. The ... Cite

Congenital bowing of the long bones (camptomelic dwarfism): a report of two cases

Journal Article Inter Clinic Information Bulletin · December 1, 1973 Cite

Purpura fulminans.

Journal Article J Bone Joint Surg Am · January 1973 Link to item Cite