Scholars@Duke
Salim Farouk Idriss

Salim Farouk Idriss

Professor of Pediatrics
Pediatrics, Cardiology
Box 3090 Med Ctr, Pediatric Cardiology, Durham, NC
Pediatric Cardiology, Dept of Pediatrics, DUMC, Durham, NC
Manage Profile
Embed Profile Data

Selected Publications

Abstract 17192: Characterization and Localization of Focal Atrial Tachycardia in Adult Congenital Heart Disease

Conference Circulation · November 7, 2023 Introduction: Patients with adult congenital heart disease (ACHD) often develop atrial arrhythmias, including focal atrial tachycardia (FAT). In non-ACHD patients, algorithms using surface ECG P-wave ... Full text Cite

Health Disparities in the Treatment of Supraventricular Tachycardia in Pediatric Patients.

Journal Article Pediatr Cardiol · December 2022 Supraventricular tachycardia (SVT) is a common pediatric arrhythmia. The objective of this investigation was to investigate the existence and degree of the health disparities in the treatment of pediatric patients with supraventricular tachycardia based on ... Full text Link to item Cite

mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis in Adolescents: A Survey Study.

Journal Article J Pediatr · April 2022 In this survey study of institutions across the US, marked variability in evaluation, treatment, and follow-up of adolescents 12 through 18 years of age with mRNA coronavirus disease 2019 (COVID-19) vaccine-associated myopericarditis was noted. Only one ad ... Full text Link to item Cite

ATP1A3-Encoded Sodium-Potassium ATPase Subunit Alpha 3 D801N Variant Is Associated With Shortened QT Interval and Predisposition to Ventricular Fibrillation Preceded by Bradycardia.

Journal Article J Am Heart Assoc · September 7, 2021 Background Pathogenic variation in the ATP1A3-encoded sodium-potassium ATPase, ATP1A3, is responsible for alternating hemiplegia of childhood (AHC). Although these patients experience a high rate of sudden unexpected death in epilepsy, the pathophysiologic ... Full text Open Access Link to item Cite

Improving Youth Sports Safety: Implementing an Emergency Action Plan for Sudden Cardiac Arrest.

Journal Article J Pediatr Nurs · 2021 BACKGROUND: Children who participate in youth sports are at risk for sudden cardiac arrest (SCA) related to undetected cardiac anomalies or abrupt impact to the chest. Nurse-led interventions may prevent sudden cardiac death by helping leagues implement an ... Full text Link to item Cite

Pacing in Patients with Congenital Heart Disease: When Is It Helpful and When Is It Harmful?

Journal Article Curr Cardiol Rep · January 16, 2020 PURPOSE OF REVIEW: Pacing in pediatric and adult patients with congenital heart disease requires careful evaluation and thoughtful planning. Review of current guidelines with assessment of risk/benefit must be performed along with planning on a case-by-cas ... Full text Link to item Cite

Recovery of the fetal electrocardiogram for morphological analysis from two trans-abdominal channels via optimal shrinkage.

Journal Article Physiol Meas · December 2, 2019 OBJECTIVE: We propose a novel algorithm to recover fetal electrocardiogram (ECG) for both the fetal heart rate analysis and morphological analysis of its waveform from two or three trans-abdominal maternal ECG channels. APPROACH: We design an algorithm bas ... Full text Link to item Cite

Variability in radiation dose and image quality: A comparison across fluoroscopy-system vendors, generations of equipment and institutions.

Journal Article Catheter Cardiovasc Interv · December 1, 2018 OBJECTIVES: To evaluate differences in radiation dose and image quality across institutions, fluoroscope vendors and generations of fluoroscopes for pediatric cardiac catheterization. BACKGROUND: Increased recognition of the potentially harmful effects of ... Full text Link to item Cite

The Second Annual Think Tank on Prevention of Sudden Cardiac Death in the Young: Developing a rational, reliable, and sustainable national health care resource. A report from the Cardiac Safety Research Consortium.

Journal Article Am Heart J · August 2018 Sudden cardiac death in the young (SCDY) spans gender, race, ethnicity, and socioeconomic class. The loss of any pediatric patient is a matter of national and international public health concern, and focused efforts should be aimed at preventing these burd ... Full text Link to item Cite

Arrhythmias and pacing

Chapter · January 1, 2018 The rapid recognition, diagnosis, and management of cardiac arrhythmias are essential skills in the intensive care unit (ICU). Outcomes can hinge on the timely initiation of arrhythmia therapy. The aim of this chapter is to serve as a useful, practical res ... Full text Cite

Prevention of sudden cardiac death in the young: Developing a rational, reliable, and sustainable national health care resource. A report from the Cardiac Safety Research Consortium.

Journal Article Am Heart J · August 2017 This White Paper, prepared by members of the Cardiac Safety Research Consortium, discusses important issues regarding sudden cardiac death in the young (SCDY), a problem that does not discriminate by gender, race, ethnicity, education, socioeconomic level, ... Full text Link to item Cite

The comparative relationships between locations of the papillary muscles and electrophysiologic QRS axis in patients with atrioventricular septal defect and common as opposed to separate orifices in the valve guarding the common atrioventricular junction.

Journal Article Cardiol Young · March 2017 BACKGROUND: Knowledge regarding factors that influence deviation of the QRS axis is important when seeking to differentiate between physiological and pathological changes. We hypothesised that, in contrast to those patients with an atrioventricular septal ... Full text Link to item Cite

Development and impact of arrhythmias after the Norwood procedure: A report from the Pediatric Heart Network.

Journal Article J Thorac Cardiovasc Surg · March 2017 OBJECTIVES: The study objective was to determine the predictors of new-onset arrhythmia among infants with single-ventricle anomalies during the post-Norwood hospitalization and the association of those arrhythmias with postoperative outcomes (ventilator t ... Full text Link to item Cite

Radiofrequency Ablation in the Sinus of Valsalva for Ventricular Arrhythmia in Pediatric Patients.

Journal Article Pediatr Cardiol · December 2016 The need to perform catheter ablation of ventricular arrhythmia from within the sinuses of Valsalva in a pediatric patient is uncommon. This has been reported in adults, but there are little data about the feasibility, safety or efficacy of catheter ablati ... Full text Link to item Cite

Diagnosis of arrhythmias and conductive disorders

Chapter · January 1, 2014 The ability to diagnose basic arrhythmias and conduction disorders in infants, children, adolescents, and adults with congenital heart disease is a fundamental of pediatric and adult congenital cardiovascular medicine. This chapter provides basic knowledge ... Full text Cite

Abstract 17192: Characterization and Localization of Focal Atrial Tachycardia in Adult Congenital Heart Disease

Conference Circulation · November 7, 2023 Introduction: Patients with adult congenital heart disease (ACHD) often develop atrial arrhythmias, including focal atrial tachycardia (FAT). In non-ACHD patients, algorithms using surface ECG P-wave ... Full text Cite

Health Disparities in the Treatment of Supraventricular Tachycardia in Pediatric Patients.

Journal Article Pediatr Cardiol · December 2022 Supraventricular tachycardia (SVT) is a common pediatric arrhythmia. The objective of this investigation was to investigate the existence and degree of the health disparities in the treatment of pediatric patients with supraventricular tachycardia based on ... Full text Link to item Cite

mRNA Coronavirus Disease 2019 Vaccine-Associated Myopericarditis in Adolescents: A Survey Study.

Journal Article J Pediatr · April 2022 In this survey study of institutions across the US, marked variability in evaluation, treatment, and follow-up of adolescents 12 through 18 years of age with mRNA coronavirus disease 2019 (COVID-19) vaccine-associated myopericarditis was noted. Only one ad ... Full text Link to item Cite

ATP1A3-Encoded Sodium-Potassium ATPase Subunit Alpha 3 D801N Variant Is Associated With Shortened QT Interval and Predisposition to Ventricular Fibrillation Preceded by Bradycardia.

Journal Article J Am Heart Assoc · September 7, 2021 Background Pathogenic variation in the ATP1A3-encoded sodium-potassium ATPase, ATP1A3, is responsible for alternating hemiplegia of childhood (AHC). Although these patients experience a high rate of sudden unexpected death in epilepsy, the pathophysiologic ... Full text Open Access Link to item Cite

Improving Youth Sports Safety: Implementing an Emergency Action Plan for Sudden Cardiac Arrest.

Journal Article J Pediatr Nurs · 2021 BACKGROUND: Children who participate in youth sports are at risk for sudden cardiac arrest (SCA) related to undetected cardiac anomalies or abrupt impact to the chest. Nurse-led interventions may prevent sudden cardiac death by helping leagues implement an ... Full text Link to item Cite

Pacing in Patients with Congenital Heart Disease: When Is It Helpful and When Is It Harmful?

Journal Article Curr Cardiol Rep · January 16, 2020 PURPOSE OF REVIEW: Pacing in pediatric and adult patients with congenital heart disease requires careful evaluation and thoughtful planning. Review of current guidelines with assessment of risk/benefit must be performed along with planning on a case-by-cas ... Full text Link to item Cite

Recovery of the fetal electrocardiogram for morphological analysis from two trans-abdominal channels via optimal shrinkage.

Journal Article Physiol Meas · December 2, 2019 OBJECTIVE: We propose a novel algorithm to recover fetal electrocardiogram (ECG) for both the fetal heart rate analysis and morphological analysis of its waveform from two or three trans-abdominal maternal ECG channels. APPROACH: We design an algorithm bas ... Full text Link to item Cite

Variability in radiation dose and image quality: A comparison across fluoroscopy-system vendors, generations of equipment and institutions.

Journal Article Catheter Cardiovasc Interv · December 1, 2018 OBJECTIVES: To evaluate differences in radiation dose and image quality across institutions, fluoroscope vendors and generations of fluoroscopes for pediatric cardiac catheterization. BACKGROUND: Increased recognition of the potentially harmful effects of ... Full text Link to item Cite

The Second Annual Think Tank on Prevention of Sudden Cardiac Death in the Young: Developing a rational, reliable, and sustainable national health care resource. A report from the Cardiac Safety Research Consortium.

Journal Article Am Heart J · August 2018 Sudden cardiac death in the young (SCDY) spans gender, race, ethnicity, and socioeconomic class. The loss of any pediatric patient is a matter of national and international public health concern, and focused efforts should be aimed at preventing these burd ... Full text Link to item Cite

Arrhythmias and pacing

Chapter · January 1, 2018 The rapid recognition, diagnosis, and management of cardiac arrhythmias are essential skills in the intensive care unit (ICU). Outcomes can hinge on the timely initiation of arrhythmia therapy. The aim of this chapter is to serve as a useful, practical res ... Full text Cite

Prevention of sudden cardiac death in the young: Developing a rational, reliable, and sustainable national health care resource. A report from the Cardiac Safety Research Consortium.

Journal Article Am Heart J · August 2017 This White Paper, prepared by members of the Cardiac Safety Research Consortium, discusses important issues regarding sudden cardiac death in the young (SCDY), a problem that does not discriminate by gender, race, ethnicity, education, socioeconomic level, ... Full text Link to item Cite

The comparative relationships between locations of the papillary muscles and electrophysiologic QRS axis in patients with atrioventricular septal defect and common as opposed to separate orifices in the valve guarding the common atrioventricular junction.

Journal Article Cardiol Young · March 2017 BACKGROUND: Knowledge regarding factors that influence deviation of the QRS axis is important when seeking to differentiate between physiological and pathological changes. We hypothesised that, in contrast to those patients with an atrioventricular septal ... Full text Link to item Cite

Development and impact of arrhythmias after the Norwood procedure: A report from the Pediatric Heart Network.

Journal Article J Thorac Cardiovasc Surg · March 2017 OBJECTIVES: The study objective was to determine the predictors of new-onset arrhythmia among infants with single-ventricle anomalies during the post-Norwood hospitalization and the association of those arrhythmias with postoperative outcomes (ventilator t ... Full text Link to item Cite

Radiofrequency Ablation in the Sinus of Valsalva for Ventricular Arrhythmia in Pediatric Patients.

Journal Article Pediatr Cardiol · December 2016 The need to perform catheter ablation of ventricular arrhythmia from within the sinuses of Valsalva in a pediatric patient is uncommon. This has been reported in adults, but there are little data about the feasibility, safety or efficacy of catheter ablati ... Full text Link to item Cite

Diagnosis of arrhythmias and conductive disorders

Chapter · January 1, 2014 The ability to diagnose basic arrhythmias and conduction disorders in infants, children, adolescents, and adults with congenital heart disease is a fundamental of pediatric and adult congenital cardiovascular medicine. This chapter provides basic knowledge ... Full text Cite

Multicenter study comparing shunt type in the norwood procedure for single-ventricle lesions: three-dimensional echocardiographic analysis.

Journal Article Circ Cardiovasc Imaging · November 2013 BACKGROUND: The Pediatric Heart Network's Single Ventricle Reconstruction (SVR) trial randomized infants with single right ventricles (RVs) undergoing a Norwood procedure to a modified Blalock-Taussig or RV-to-pulmonary artery shunt. This report compares R ... Full text Link to item Cite

Comparison of Fontan survivors with and without pacemakers: a report from the Pediatric Heart Network Fontan Cross-Sectional Study.

Journal Article Congenit Heart Dis · 2013 Featured Publication OBJECTIVE: Although many Fontan patients undergo pacemaker placement, there are few studies characterizing this population. Our purpose was to compare clinical characteristics, functional status and measures of ventricular performance in Fontan patients wi ... Full text Link to item Cite

Feasibility of non-invasive determination of the stability of propagation reserve in patients

Journal Article Computing in Cardiology · December 1, 2012 This study investigates the feasibility of using surface ECG recordings to assess stability of cardiac propagation. Our novel method customizes a reaction-diffusion model of cardiac excitation using measurements of patient's repolarization dynamics. The cu ... Cite

Arrhythmias in a contemporary fontan cohort: prevalence and clinical associations in a multicenter cross-sectional study.

Journal Article J Am Coll Cardiol · September 7, 2010 Featured Publication OBJECTIVES: Our aim was to examine the prevalence of arrhythmias and identify independent associations of time to arrhythmia development. BACKGROUND: Since introduction of the Fontan operation in 1971, long-term results have steadily improved with newer mo ... Full text Link to item Cite

Effect of resistive barrier location on the relationship between T-wave alternans and cellular repolarization alternans: a 1-D modeling study.

Journal Article J Electrocardiol · 2010 Featured Publication Structural inhomogeneities in cardiac tissue have been associated with increased cellular repolarization alternans in animal experiments and increased T-wave alternans (TWA) in clinical studies. However, the effect of structural inhomogeneities on the rela ... Full text Link to item Cite

Electroanatomic relationships in patients with primum atrioventricular septal defect.

Journal Article JACC Cardiovasc Imaging · December 2009 Featured Publication OBJECTIVES: The objective of this study was to test the hypothesis that patients with primum atrioventricular septal defect (AVSD) have an imbalance in the positions of the left ventricular papillary muscles compared with healthy subjects, and that this an ... Full text Link to item Cite

Determination of the mitral papillary muscle positions by the septal-to-free wall arc ratio method.

Journal Article Clin Physiol Funct Imaging · May 2009 Featured Publication BACKGROUND: Determination of mitral papillary muscle positions is of increasing interest in wide spectrum of clinical cardiology fields. Particularly, relative positioning of the papillary muscles between the inter-ventricular septum and the left ventricul ... Full text Link to item Cite

Arrhythmias in children having a single left superior vena cava and minimal structural heart disease.

Journal Article J Cardiovasc Electrophysiol · February 2009 Featured Publication BACKGROUND: The presence of a single left superior vena cava in the absence of complex congenital heart disease is uncommon, and, in the absence of hemodynamic consequences, it would not be expected to result in cardiovascular signs or symptoms. Single cas ... Full text Link to item Cite

Relationship between extracellular T-wave height, T-wave alternans amplitude, and tissue action potential alternans: a 1-dimensional computer modeling study.

Journal Article J Electrocardiol · 2009 Featured Publication T-wave alternans (TWA) is a useful marker of cardiac instability, but not much is known about the factors that affect its measurement, such as electrode placement. We used a 1-dimensional myocardial fiber computer model of alternans to investigate the effe ... Full text Link to item Cite

Variability of action potential duration in pharmacologically induced long QT syndrome type 1.

Journal Article Annu Int Conf IEEE Eng Med Biol Soc · 2009 Featured Publication Long QT Syndrome (LQTS) is a congenital disorder associated with life-threatening arrhythmias. LQT1, a type of LQTS affecting the slow delayed rectifier potassium current, shows a higher incidence of arrhythmia associated with sympathetic stimulation than ... Full text Link to item Cite

Variability of action potential duration in pharmacologically induced long QT syndrome type 1.

Journal Article Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference · January 1, 2009 Long QT Syndrome (LQTS) is a congenital disorder associated with life-threatening arrhythmias. LQT1, a type of LQTS affecting the slow delayed rectifier potassium current, shows a higher incidence of arrhythmia associated with sympathetic stimulation than ... Cite

Cardiac repolarization instability during normal postnatal development.

Journal Article J Electrocardiol · 2008 Featured Publication Long QT syndrome is a disease characterized by abnormal lengthening of the QT interval and by sudden cardiac death. It is a disease of development, with the incidence of a sudden event increasing during childhood. Repolarization instability during postnata ... Full text Link to item Cite

Vibrating interventional device detection using real-time 3-D color Doppler.

Journal Article IEEE Trans Ultrason Ferroelectr Freq Control · 2008 Featured Publication Ultrasound image guidance of interventional devices during minimally invasive surgery provides the clinician with improved soft tissue contrast while reducing ionizing radiation exposure. One problem with ultrasound image guidance is poor visualization of ... Full text Link to item Cite

Vibrating interventional device detection using real-time 3D color doppler

Journal Article Proceedings - IEEE Ultrasonics Symposium · December 1, 2007 We have previously described guidance of several interventional devices using a real time 3D (RT3D) ultrasound system with 3D color Doppler combined with the ColorMark technology. We then developed an analytical model for a vibrating needle to maximize the ... Full text Cite

Real-time three-dimensional transesophageal echocardiography for guiding interventional electrophysiology: feasibility study.

Journal Article Ultrason Imaging · July 2007 Featured Publication At present, there are limited methods of acquiring three-dimensional visualization of cardiac structure and function in real-time during interventional electrophysiology procedures. Images acquired for integration of computerized tomography and magnetic re ... Full text Link to item Cite

Spatial heterogeneity of the restitution portrait in rabbit epicardium.

Journal Article Am J Physiol Heart Circ Physiol · March 2007 Featured Publication Spatial heterogeneity of repolarization can provide a substrate for reentry to occur in myocardium. This heterogeneity may result from spatial differences in action potential duration (APD) restitution. The restitution portrait (RP) measures many aspects o ... Full text Link to item Cite

The Electrocardiogram Restitution Portrait Quantifying Dynamical Electrical Instability in Young Myocardium.

Journal Article Comput Cardiol · 2007 Featured Publication Novel methods need to be developed to detect electrical instability in children. The dynamical properties of action potential restitution play an important role in the development of instability leading to arrhythmias. A new method, the Restitution Portrai ... Link to item Cite

A low-cost high-efficiency fiber-optic coupler for recording action potentials within the myocardial wall.

Journal Article IEEE Trans Biomed Eng · August 2006 Featured Publication We present a high-efficiency, low-cost wavelength division multiplexer to record cardiac optical action potentials (APs) within the myocardial wall using optical fibers. APs with signal-to-noise ratio as high as 60, without spatial or temporal averaging, a ... Full text Link to item Cite

Electrocardiographic response to enzyme replacement therapy for Pompe disease.

Journal Article Genet Med · May 2006 Featured Publication PURPOSE: Electrocardiogram (ECG) abnormalities are universal in infantile Pompe disease or glycogen storage disease type II, a fatal genetic muscle disorder caused by deficiency of acid alpha-glucosidase (GAA). Hallmarks of this disease include a shortened ... Full text Link to item Cite

Real-time, 3-D ultrasound with multiple transducer arrays.

Journal Article IEEE Trans Ultrason Ferroelectr Freq Control · January 2006 Featured Publication Modifications were made to a commercial real-time, three-dimensional (3-D) ultrasound system for near simultaneous 3-D scanning with two matrix array transducers. As a first illustration, a transducer cable assembly was modified to incorporate two independ ... Full text Link to item Cite

Efficacy of signal-averaged electrocardiography in the young orthotopic heart transplant patient to detect allograft rejection.

Journal Article Pediatr Cardiol · 2006 Featured Publication Endomyocardial biopsy is the gold standard survey for cardiac graft rejection. Signal-averaged electrocardiography (SAECG) identifies slowly conducting, diseased myocardium. We sought to determine whether SAECG is a sensitive, noninvasive transplant survei ... Full text Link to item Cite

Real-time 3D ultrasound laparoscopy

Journal Article Proceedings - IEEE Ultrasonics Symposium · December 1, 2005 We have previously described 2D array ultrasound transducers operating up to 13.5 MHz for applications including real time 3D transthoracic imaging, real time volumetric intracardiac echocardiography (ICE), real time transesophageal echocardiography (TEE) ... Full text Cite

Real-time 3D laparoscopic ultrasonography.

Journal Article Ultrason Imaging · July 2005 Featured Publication We have previously described 2D array ultrasound transducers operating up to 10 MHz for applications including real time 3D transthoracic imaging, real time volumetric intracardiac echocardiography (ICE), real time 3D intravascular ultrasound (IVUS) imagin ... Full text Link to item Cite

A MULTICHANNEL FIBER-OPTIC MAPPING SYSTEM FOR INTRAMURAL RECORDING OF CARDIAC ACTION POTENTIALS.

Journal Article IFMBE Proc · 2005 Featured Publication Measuring cardiac action potentials at many sites within the ventricular wall is important for understanding cardiac arrhythmias; however, recording in the depth of the heart wall presents many difficulties. We have developed a multichannel optical mapping ... Full text Link to item Cite

Real time 3D ultrasound imaging of the brain

Journal Article Proceedings - IEEE Ultrasonics Symposium · December 1, 2004 We tested the feasibility of real time three dimensional ultrasound imaging in the brain with a 2.5MHz 2D array using a Volumetrics Model 1 scanner. In a human subject, the real time 3D scans produced simultaneous transcranial axial, coronal and saggital i ... Cite

Real-time 3D transesophageal echocardiography

Journal Article Proceedings - IEEE Ultrasonics Symposium · December 1, 2004 Transesophageal echocardiography (TEE) is established as an essential diagnostic tool for patients that are obese or that exhibit signs of pulmonary disease. However, current techniques in transesophageal scanning of the heart are limited by the maneuverab ... Cite

Real-time 3D color doppler for guidance of vibrating interventional devices

Journal Article Proceedings - IEEE Ultrasonics Symposium · December 1, 2004 The goal of this investigation is to examine the feasibility of guiding interventional devices using piezoelectric buzzers to create a velocity source, which is imaged and tracked with real time 3D (RT3D) ultrasound and Color Doppler. Interventional device ... Cite

A miniaturized catheter 2-D array for real-time, 3-D intracardiac echocardiography.

Journal Article IEEE Trans Ultrason Ferroelectr Freq Control · October 2004 Featured Publication The design, fabrication, and characterization of a 112 channel, 5 MHz, two-dimensional (2-D) array transducer constructed on a six layer flexible polyimide interconnect circuit is described. The transducer was mounted in a 7 Fr (2.33 mm outside diameter) c ... Full text Link to item Cite

Feasibility study: real-time 3-D ultrasound imaging of the brain.

Journal Article Ultrasound Med Biol · October 2004 Featured Publication We tested the feasibility of real-time, 3-D ultrasound (US) imaging in the brain. The 3-D scanner uses a matrix phased-array transducer of 512 transmit channels and 256 receive channels operating at 2.5 MHz with a 15-mm diameter footprint. The real-time sy ... Full text Link to item Cite

Real-time 3D transesophageal echocardiography.

Journal Article Ultrason Imaging · October 2004 Featured Publication Transesophageal echocardiography (TEE) is an essential diagnostic tool in patients with poor transthoracic echocardiographic windows or when detailed imaging of structures distant from the chest wall is necessary. A real-time 3D TEE probe has been fabricat ... Full text Link to item Cite

Transmural action potential repolarization heterogeneity develops postnatally in the rabbit.

Journal Article J Cardiovasc Electrophysiol · July 2004 Featured Publication INTRODUCTION: In the hereditary long QT syndrome, arrhythmia risk changes with age despite the presence of an ion channel mutation throughout development. Age-dependent changes in the transmural dispersion of repolarization may modulate this vulnerability. ... Full text Link to item Cite

Real-time 3D color flow Doppler for guidance of vibrating interventional devices.

Journal Article Ultrason Imaging · July 2004 Featured Publication The goal of this investigation was to examine the feasibility of guiding interventional devices using piezoelectric buzzers to create velocity sources, which were imaged and tracked with real-time 3D color flow Doppler. The interventional devices examined ... Full text Link to item Cite

The restitution portrait: a new method for investigating rate-dependent restitution.

Journal Article J Cardiovasc Electrophysiol · June 2004 Featured Publication INTRODUCTION: Electrical restitution, relating action potential duration (APD) to diastolic interval (DI), was believed to determine the stability of heart rhythm. However, recent studies demonstrate that stability also depends on long-term APD changes cau ... Full text Link to item Cite

Minimum energy single-shock internal atrial defibrillation in sheep.

Journal Article J Interv Card Electrophysiol · April 2004 Featured Publication Well-tolerated internal atrial defibrillation shocks must be below the pain threshold, which has been estimated to be less than 1 Joule. Defibrillation of the atria with low energy is made possible by delivering shocks at the low end of the defibrillation ... Full text Link to item Cite

Advances in 2-D array catheter transducers for real-time three-dimensional intracardiac echocardiography

Journal Article Proceedings of the IEEE Ultrasonics Symposium · December 1, 2003 In this paper, we describe advances in the design, fabrication and testing of two-dimensional catheter-mounted arrays for real-time three-dimensional (RT3-D) intracardiac echocardiography (ICE). These include a 7 Fr (2.3 mm O.D.), 112 element 2-D array uti ... Cite

Dual lumen transducer probes for real-time 3-D interventional cardiac ultrasound.

Journal Article Ultrasound Med Biol · September 2003 Featured Publication We have developed dual lumen probes incorporating a forward-viewing matrix array transducer with an integrated working lumen for delivery of tools in real-time 3-D (RT3-D) interventional echocardiography. The probes are of 14 Fr and 22 Fr sizes, with 112 c ... Full text Link to item Cite

Transmural action potential repolarization heterogeneity develops postnatally in the rabbit

Conference JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY · March 19, 2003 Link to item Cite

Two dimensional arrays for 3-D ultrasound imaging

Journal Article Proceedings of the IEEE Ultrasonics Symposium · December 1, 2002 Phased array ultrasound transducers have been fabricated in our laboratories at Duke University since 1970. In 1986, we began the development of 2-D arrays with a 20 × 20 element Mills cross array including 64 active channels operating at 1 MHz which produ ... Cite

Microvolt T wave alternans inducibility in normal newborn puppies: effects of development.

Journal Article J Cardiovasc Electrophysiol · June 2002 Featured Publication INTRODUCTION: The cause of sudden infant death syndrome is unknown, but increased cardiac vulnerability due to repolarization instability may be a contributing factor. The QT interval normally is long at birth and increases further during the first few pos ... Full text Link to item Cite

Feasibility study of real-time three-dimensional intracardiac echocardiography for guidance of interventional electrophysiology.

Journal Article Pacing Clin Electrophysiol · March 2002 Featured Publication The authors tested the feasibility of real-time three-dimensional intracardiac echocardiography for guidance of interventional electrophysiological studies. The three-dimensional scanner uses a matrix array ultrasound transducer of 64 channels operating at ... Full text Link to item Cite

Feasibility study for real time three dimensional Doppler intracardiac echocardiography.

Journal Article Ultrason Imaging · January 2002 Featured Publication Using catheter-mounted two-dimensional array transducers, we have obtained real-time three-dimensional color flow and spectral Doppler ultrasound images in phantoms. We have constructed several transducers operating at 5 MHz with up to 137 channels inside ... Full text Link to item Cite

Real-time three dimensional intracardiac echocardiography for guidance of cardiac interventional procedures

Journal Article Proceedings of the IEEE Ultrasonics Symposium · December 1, 2001 We have tested the feasibility of real-time three dimensional intracardiac echocardiography for guidance of interventional electrophysiology studies. We have constructed 2D array ultrasound transducers operating at 5MHz with 64 channels in a 12 F catheter, ... Cite

Real-time three-dimensional intracardiac echocardiography.

Journal Article Ultrasound Med Biol · September 2001 Featured Publication Using catheter-mounted 2-D array transducers, we have obtained real-time 3-D intracardiac ultrasound (US) images. We have constructed several transducers with 64 channels inside a 12 French catheter lumen operating at 5 MHz. The transducer configuration ma ... Full text Link to item Cite

Two dimensional arrays for real time volumetric and intracardiac imaging with simultaneous electrocardiogram

Journal Article Proceedings of the IEEE Ultrasonics Symposium · December 1, 2000 Design, fabrication and performance of a two-dimensional array operating at 10 MHz for real time volumetric and intracardiac imaging with simultaneous electrocardiagram was presented. Use of the device to monitor and quantify RF ablation study was demonstr ... Cite

Effect of pacing site on ventricular fibrillation initiation by shocks during the vulnerable period.

Journal Article Am J Physiol · November 1999 Featured Publication The critical point hypothesis for the upper limit of vulnerability (ULV) states that the site of S1 pacing should not affect the ULV S2 shock strength for a single S2 shock electrode configuration but may affect the S1-S2 interval at which sub-ULV shocks i ... Full text Link to item Cite

Effect of pacing site on ventricular fibrillation initiation by shocks during the vulnerable period

Journal Article AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY · November 1, 1999 Link to item Cite

Influence of epicardial patches on defibrillation threshold with nonthoracotomy lead configurations.

Journal Article Circulation · November 15, 1995 Featured Publication BACKGROUND: In previous studies, epicardial patch electrodes decreased transthoracic defibrillation efficacy. We studied the effects of two inactive epicardial 14-cm2 titanium mesh patches on defibrillation energy requirements with nonthoracotomy internal ... Full text Link to item Cite

Effect of rapid pacing and T-wave scanning on the relation between the defibrillation and upper-limit-of-vulnerability dose-response curves.

Journal Article Circulation · September 1, 1995 Featured Publication BACKGROUND: The critical-point and upper-limit-of-vulnerability (ULV) hypotheses predict that the ULV dose-response curve should be steeper and to the right of the defibrillation (DF) curve. Yet, some recent experimental data contradict this prediction. Tw ... Full text Link to item Cite

Predicting the potential gradient field in ventricular fibrillation from shocks delivered in paced rhythm.

Journal Article Am J Physiol · June 1995 Featured Publication A method of defibrillation threshold determination that utilizes low-strength shocks delivered in a benign rhythm would be desirable. Because the two-dimensional epicardial potential gradient (PG) is a shock parameter that is linked to defibrillation, we e ... Full text Link to item Cite

PREDICTING THE POTENTIAL GRADIENT FIELD IN VENTRICULAR-FIBRILLATION FROM SHOCKS DELIVERED IN PACED RHYTHM

Journal Article AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY · June 1, 1995 Link to item Cite

Comparison of defibrillation probability of success curves for an endocardial lead configuration with and without an inactive epicardial patch.

Journal Article J Am Coll Cardiol · May 1995 Featured Publication OBJECTIVES: This study sought to assess the effect of passive "bystander" epicardial electrodes on defibrillation efficacy. BACKGROUND: We hypothesized that an inactive epicardial patch placed in an area of low potential gradient from an endocardial electr ... Full text Link to item Cite

The effect of cardiac compression on defibrillation efficacy and the upper limit of vulnerability.

Journal Article J Cardiovasc Electrophysiol · May 1995 Featured Publication INTRODUCTION: We determined the effects of decreasing the ventricular blood volume and altering cardiac geometry on defibrillation, the upper limit of vulnerability (ULV), and the relationship between them. METHODS AND RESULTS: In six pigs, fibrillation/de ... Full text Link to item Cite

RAPID PACING MOVES THE UPPER LIMIT OF VULNERABILITY HIGHER ON THE DEFIBRILLATION PROBABILITY OF SUCCESS CURVE

Journal Article JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY · February 1, 1994 Link to item Cite

Efficient electrode spacing for examining spatial organization during ventricular fibrillation.

Journal Article IEEE Trans Biomed Eng · October 1993 Featured Publication Spatial organization has been observed during episodes of ventricular fibrillation (VF) by recording epicardial unipolar electrograms on a grid of electrodes. In such studies, the choice of spacing between electrodes is an important decision, affecting the ... Full text Link to item Cite

Minimum electrode spacing for mapping ventricular fibrillation using spatial sampling theory

Conference Proceedings - Computers in Cardiology, CIC 1992 · January 1, 1992 Electrode arrays are commonly used to study spatial patterns during ventricular fibrillation (VF) where the choice of spacing between electrodes is an important decision. The Nyquist criterion states that an electrode spacing smaller than half the smallest ... Full text Cite

Errors in calculating the epicardial potential gradient field from unipolar voltage measurements during cardiac defibrillation

Journal Article Proceedings of the Annual Conference on Engineering in Medicine and Biology · December 1, 1991 An examination is made of the errors generated when calculating the magnitude of the epicardial potential gradient using voltages recorded from three unipolar electrodes in a fixed triangular geometry on the epicardial surface. The error sensitivity of the ... Cite