Journal ArticleCereb Cortex · March 6, 2025
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Evidence has linked head trauma to increased risk factors for neuropathology, including mechanical deformation of the sulcal fundus and, later, perivascular accumulation of hyperphosphorylated tau adjacent to these spaces related to chronic traumatic encep ...
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Journal ArticleBrain Commun · 2025
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Quantitative susceptibility mapping has been applied to map brain iron distribution after mild traumatic brain injury to understand properties of neural tissue which may be related to cellular dyshomeostasis. However, this is a heterogeneous injury associa ...
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Journal ArticleImaging Neurosci (Camb) · 2025
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Neurodegeneration associated with Alzheimer's disease (AD) can start at the microstructural level years before cognitive symptoms; yet, it has been difficult to definitively detect these early changes to plan effective treatments. Using a cortical column-b ...
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Journal ArticleMagn Reson Med · February 2024
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PURPOSE: To develop a flexible, lightweight, and multi-purpose integrated parallel reception, excitation, and shimming (iPRES) coil array that can conform to the subject's anatomy and perform MR imaging and localized B0 shimming in different anatomical reg ...
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Journal ArticleCereb Cortex · January 31, 2024
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In addition to amyloid beta plaques and neurofibrillary tangles, Alzheimer's disease (AD) has been associated with elevated iron in deep gray matter nuclei using quantitative susceptibility mapping (QSM). However, only a few studies have examined cortical ...
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Journal ArticlePhys Med Biol · June 8, 2023
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Objective.A novel magnetic resonance imaging (MRI) radio-frequency (RF) coil design, termed an integrated RF/wireless (iRFW) coil design, can simultaneously perform MRI signal reception and far-field wireless data transfer with the same coil conductors bet ...
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Journal ArticleNeuroimage · April 15, 2023
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High-resolution diffusion tensor imaging (DTI) can noninvasively probe the microstructure of cortical gray matter in vivo. In this study, 0.9-mm isotropic whole-brain DTI data were acquired in healthy subjects with an efficient multi-band multi-shot echo-p ...
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Journal ArticleMagn Reson Med · August 2022
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PURPOSE: To develop a wireless integrated parallel reception, excitation, and shimming (iPRES-W) coil array for simultaneous imaging and wireless localized B0 shimming, and to demonstrate its ability to correct for distortions in DTI of the spinal cord in ...
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Journal ArticleJ Magn Reson Imaging · April 2022
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Radio-frequency (RF) coils are to magnetic resonance imaging (MRI) scanners what eyes are to the human body. Because of their critical importance, there have been constant innovations driving the rapid development of RF coil technologies. Over the past fou ...
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Journal ArticleMagn Reson Med · December 2021
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PURPOSE: Gradient-echo echo-planar imaging (EPI), which is typically used for blood oxygenation level-dependent (BOLD) functional MRI (fMRI), suffers from distortions and signal loss caused by localized B0 inhomogeneities. Such artifacts cannot be effectiv ...
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Journal ArticleCogn Affect Behav Neurosci · August 2019
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As we age we have increasing difficulty with phonological aspects of language production. Yet semantic processes are largely stable across the life span. This suggests a fundamental difference in the cognitive and potentially neural architecture supporting ...
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Journal ArticleMagn Reson Med · June 2019
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PURPOSE: Neuroimaging techniques are widely used to investigate the function of the human brain, but none are currently able to accurately localize neuronal activity with both high spatial and temporal specificity. Here, a new in vivo MRI acquisition and a ...
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Journal ArticleMagn Reson Med · March 2019
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PURPOSE: An innovative radio-frequency (RF) coil design that allows RF currents both at the Larmor frequency and in a wireless communication band to flow on the same coil is proposed to enable simultaneous MRI signal reception and wireless data transfer, t ...
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Journal ArticleMagn Reson Med · July 2018
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PURPOSE: Integrated parallel reception, excitation, and shimming coil arrays with N shim loops per radio-frequency (RF) coil element (iPRES(N)) allow an RF current and N direct currents (DC) to flow in each coil element, enabling simultaneous reception/exc ...
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Journal ArticleMagn Reson Med · July 2017
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PURPOSE: Either SENSE+CG or POCS-ICE methods can be used to correct for motion-induced phase errors in navigator-free multishot diffusion imaging. SENSE+CG has the advantage of a fast convergence, however, occasionally the convergence can be unstable, thus ...
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Journal ArticleMagn Reson Med · May 2017
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PURPOSE: Integrated parallel reception, excitation, and shimming (iPRES) coil arrays allow radio-frequency currents and direct currents to flow in the same coils, which enables excitation/reception and localized B0 shimming with a single coil array. The pu ...
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Journal ArticleMagn Reson Med · November 2015
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PURPOSE: A projection onto convex sets reconstruction of multiplexed sensitivity encoded MRI (POCSMUSE) is developed to reduce motion-related artifacts, including respiration artifacts in abdominal imaging and aliasing artifacts in interleaved diffusion-we ...
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Journal ArticleBiomed Res Int · 2015
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In most diffusion tensor imaging (DTI) studies, images are acquired with either a partial-Fourier or a parallel partial-Fourier echo-planar imaging (EPI) sequence, in order to shorten the echo time and increase the signal-to-noise ratio (SNR). However, edd ...
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Journal ArticleNeuroimage · December 2014
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The purpose of this work was to develop a novel integrated radiofrequency and shim (RF/shim) coil array that can perform parallel reception and localized B0 shimming in the human brain with the same coils, thereby maximizing both the signal-to-noise ratio ...
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Journal ArticleMagn Reson Med · March 2014
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PURPOSE: To present a novel technique for high-resolution stimulated echo diffusion tensor imaging with self-navigated interleaved spirals readout trajectories that can inherently and dynamically correct for image artifacts due to spatial and temporal vari ...
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Journal ArticleMagn Reson Med · February 2014
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PURPOSE: To develop and compare three novel reconstruction methods designed to inherently correct for motion-induced phase errors in multishot spiral diffusion tensor imaging without requiring a variable-density spiral trajectory or a navigator echo. THEOR ...
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Journal ArticlePLoS One · 2014
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Diffusion tensor imaging (DTI) is typically used to study white matter fiber pathways, but may also be valuable to assess the microstructure of cortical gray matter. Although cortical diffusion anisotropy has previously been observed in vivo, its cortical ...
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Journal ArticleJ Magn Reson · November 2013
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Lorentz Effect Imaging (LEI) is an MRI technique that has been proposed for direct imaging of neuronal activity. While promising results have been obtained in phantoms and in the human median nerve in vivo, its contrast mechanism is still not fully underst ...
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Journal ArticleMagn Reson Med · July 2013
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PURPOSE: To develop a new concept for a hardware platform that enables integrated parallel reception, excitation, and shimming. THEORY: This concept uses a single coil array rather than separate arrays for parallel excitation/reception and B0 shimming. It ...
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Journal ArticleMagn Reson Med · October 2012
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Multishot spiral imaging is a promising alternative to echo-planar imaging for high-resolution diffusion-weighted imaging and diffusion tensor imaging. However, subject motion in the presence of diffusion-weighting gradients causes phase inconsistencies am ...
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Journal ArticleNeuroimage · August 15, 2011
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In diffusion tensor imaging (DTI), spatial and temporal variations of the static magnetic field (B(0)) caused by susceptibility effects and time-varying eddy currents result in severe distortions, blurring, and misregistration artifacts, which in turn lead ...
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Journal ArticleJ Cogn Neurosci · November 2010
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Although people do not normally try to remember associations between faces and physical contexts, these associations are established automatically, as indicated by the difficulty of recognizing familiar faces in different contexts ("butcher-on-the-bus" phe ...
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Journal ArticleMagn Reson Med · October 2010
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Spiral imaging is vulnerable to spatial and temporal variations of the amplitude of the static magnetic field (B(0)) caused by susceptibility effects, eddy currents, chemical shifts, subject motion, physiological noise, and system instabilities, resulting ...
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Journal ArticleInternational Journal of Imaging Systems and Technology · March 1, 2010
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In this manuscript, we review the development of an alternative functional magnetic resonance imaging (fMRI) contrast mechanism based on the apparent diffusion coefficient (ADC), in light of the recent progress in other complementary functional imaging con ...
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Journal ArticleJ Neurosci · February 17, 2010
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The core feature of an economic exchange is a decision to trade one good for another, based on a comparison of relative value. Economists have long recognized, however, that the value an individual ascribes to a good during decision making (i.e., their rel ...
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Journal ArticleNeuroimage · August 1, 2009
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Although the blood oxygenation level-dependent (BOLD) contrast is widely used in functional MRI (fMRI), its spatial specificity is compromised by the diversity of the participating vasculature, including large draining veins. Previous studies have shown th ...
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Journal ArticleMethods Mol Biol · 2009
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Neuroscience methods entailing in vivo measurements of brain activity have greatly contributed to our understanding of brain function for the past decades, from the invasive early studies in animals using single-cell electrical recordings, to the noninvasi ...
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Journal ArticleNeuroimage · March 1, 2008
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Diffusion tensor imaging (DTI) is vulnerable to geometric distortions caused by subject-dependent susceptibility effects and diffusion-weighting direction-dependent eddy currents. Although the introduction of sensitivity encoding (SENSE) has reduced the ov ...
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Journal ArticleJ Magn Reson · March 2008
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Current functional MRI techniques relying on hemodynamic modulations are inherently limited in their ability to accurately localize neural activity in space and time. To address these limitations, we previously proposed a novel technique based on the Loren ...
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Journal ArticleMagn Reson Med · January 2008
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Blood oxygenation level-dependent (BOLD) functional MRI (fMRI) can be severely hampered by signal loss due to susceptibility-induced static magnetic field (B(0)) inhomogeneities near air/tissue interfaces. A single-shot spiral-in/out sequence with a z-shim ...
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Journal ArticleMagn Reson Med · February 2007
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It has been suggested that apparent diffusion coefficient (ADC) contrast can be sensitive to cerebral blood flow (CBF) changes during brain activation. However, current ADC imaging techniques have an inherently low temporal resolution due to the requiremen ...
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Journal ArticleProc Natl Acad Sci U S A · August 15, 2006
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Neuroimaging techniques are among the most important tools for investigating the function of the human nervous system and for improving the clinical diagnosis of neurological disorders. However, most commonly used techniques are limited by their invasivene ...
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Journal ArticleMagn Reson Med · June 2006
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With the rapid development of human MRI at field strengths > or = 7 T, knowledge of T(2) (*) relaxation times at such field strengths is needed to optimize acquisition parameters and understand relaxation mechanisms in many applications. However, standard ...
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Journal ArticleJ Magn Reson · March 2006
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The blood oxygenation level-dependent (BOLD) effect is the most commonly used contrast mechanism in functional magnetic resonance imaging (fMRI), due to its relatively high spatial resolution and sensitivity. However, the ability of BOLD fMRI to accurately ...
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Journal ArticleMagn Reson Imaging · February 2006
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To characterize the severe static (B(0)) and radiofrequency (B(1)) magnetic field inhomogeneity in ultra-high field (> or =7 T) magnetic resonance imaging, gradient echo (GE) and spin echo (SE) images of in vivo and postmortem human brains were acquired. T ...
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Journal ArticlePhysical Review B Condensed Matter and Materials Physics · January 1, 2003
Using electrochemical deposition, 6 μm long Ni nanowires, with typical diameters of the order of 80 nm, are grown in ion-track etched membranes. Electric contacts are established during the growth, allowing resistance measurements of a single magnetic wire ...
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Journal ArticleMagn Reson Imaging · December 2002
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Three-dimensional numerical simulations of the static magnetic field in the human head were carried out to assess the field inhomogeneity due to magnetic susceptibility differences at tissue interfaces. We used a finite difference method and magnetic perme ...
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Journal ArticleEurophysics Letters · December 1, 2001
It is shown experimentally that a pulsed current driven through a Ni nanowire provokes an irreversible magnetization reversal at a field differing from the spontaneous switching field Hsw by ΔH of as much as 40% of Hsw. The state of t ...
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