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Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction.

Publication ,  Journal Article
Salah, HM; Pandey, A; Soloveva, A; Abdelmalek, MF; Diehl, AM; Moylan, CA; Wegermann, K; Rao, VN; Hernandez, AF; Tedford, RJ; Parikh, KS ...
Published in: JACC Basic Transl Sci
November 2021

Although there is an established bidirectional relationship between heart failure with reduced ejection fraction and liver disease, the association between heart failure with preserved ejection fraction (HFpEF) and liver diseases, such as nonalcoholic fatty liver disease (NAFLD), has not been well explored. In this paper, the authors provide an in-depth review of the relationship between HFpEF and NAFLD and propose 3 NAFLD-related HFpEF phenotypes (obstructive HFpEF, metabolic HFpEF, and advanced liver fibrosis HFpEF). The authors also discuss diagnostic challenges related to the concurrent presence of NAFLD and HFpEF and offer several treatment options for NAFLD-related HFpEF phenotypes. The authors propose that NAFLD-related HFpEF should be recognized as a distinct HFpEF phenotype.

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Published In

JACC Basic Transl Sci

DOI

EISSN

2452-302X

Publication Date

November 2021

Volume

6

Issue

11

Start / End Page

918 / 932

Location

United States

Related Subject Headings

  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Salah, H. M., Pandey, A., Soloveva, A., Abdelmalek, M. F., Diehl, A. M., Moylan, C. A., … Fudim, M. (2021). Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction. JACC Basic Transl Sci, 6(11), 918–932. https://doi.org/10.1016/j.jacbts.2021.07.010
Salah, Husam M., Ambarish Pandey, Anzhela Soloveva, Manal F. Abdelmalek, Anna Mae Diehl, Cynthia A. Moylan, Kara Wegermann, et al. “Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction.JACC Basic Transl Sci 6, no. 11 (November 2021): 918–32. https://doi.org/10.1016/j.jacbts.2021.07.010.
Salah HM, Pandey A, Soloveva A, Abdelmalek MF, Diehl AM, Moylan CA, et al. Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction. JACC Basic Transl Sci. 2021 Nov;6(11):918–32.
Salah, Husam M., et al. “Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction.JACC Basic Transl Sci, vol. 6, no. 11, Nov. 2021, pp. 918–32. Pubmed, doi:10.1016/j.jacbts.2021.07.010.
Salah HM, Pandey A, Soloveva A, Abdelmalek MF, Diehl AM, Moylan CA, Wegermann K, Rao VN, Hernandez AF, Tedford RJ, Parikh KS, Mentz RJ, McGarrah RW, Fudim M. Relationship of Nonalcoholic Fatty Liver Disease and Heart Failure With Preserved Ejection Fraction. JACC Basic Transl Sci. 2021 Nov;6(11):918–932.
Journal cover image

Published In

JACC Basic Transl Sci

DOI

EISSN

2452-302X

Publication Date

November 2021

Volume

6

Issue

11

Start / End Page

918 / 932

Location

United States

Related Subject Headings

  • 3201 Cardiovascular medicine and haematology
  • 1103 Clinical Sciences
  • 1102 Cardiorespiratory Medicine and Haematology