Journal ArticleJ Nucl Cardiol · August 2019
This document is the second of 2 companion appropriate use criteria (AUC) documents developed by the American College of Cardiology, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Socie ...
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Journal ArticleJ Am Soc Echocardiogr · May 2019
This document is the second of 2 companion appropriate use criteria (AUC) documents developed by the American College of Cardiology, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Socie ...
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Journal ArticleAm J Cardiol · August 1, 2018
Septostomy reduces right ventricular (RV) workload at the expense of hypoxemia in patients with advanced pulmonary hypertension (PH). A patent foramen ovale (PFO) may serve as a "natural" septostomy, but the incidence and impact of a PFO in PH remains unce ...
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Journal ArticleJ Am Soc Echocardiogr · April 2018
This document is 1 of 2 companion appropriate use criteria (AUC) documents developed by the American College of Cardiology, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuc ...
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Journal ArticleJ Nucl Cardiol · December 2017
This document is 1 of 2 companion appropriate use criteria (AUC) documents developed by the American College of Cardiology, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuc ...
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Chapter · September 11, 2017
In general, the effects of ionizing radiation have been a greater focus for radiologists than cardiologists. This chapter discusses the manner in which X-ray images are created to better understand the means by which a reduction in radiation dose may be ac ...
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Journal ArticleAm J Manag Care · August 2017
OBJECTIVES: Pulmonary hypertension portends a poorer prognosis for blacks versus white populations, but the underlying reasons are poorly understood. We investigated associations of disease characteristics, insurance status, and race with clinical outcomes ...
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Journal ArticleCrit Pathw Cardiol · September 2015
BACKGROUND: Calcific aortic stenosis (AS) is the most common underlying pathology in patients undergoing heart valve surgery, with an expected increasing prevalence among the aging population. METHODS AND RESULTS: We identified the temporal trends in refer ...
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Journal ArticlePulm Circ · March 2015
Diabetes complicates management in a number of disease states and adversely impacts survival; how diabetes affects patients with pulmonary hypertension (PH) has not been well characterized. With insulin resistance having recently been demonstrated in PH, w ...
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Journal ArticleAm J Cardiol · January 1, 2015
We aimed to characterize the hemodynamic progression of aortic stenosis (AS) in a contemporary unselected cohort of patients with preserved left ventricular ejection fraction. Current guidelines recommend echocardiographic surveillance of hemodynamic progr ...
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Journal ArticleJ Thromb Thrombolysis · July 2014
A 75-year old woman with a history of coronary disease status post 3-vessel coronary artery bypass grafting (CABG) 8 years ago and a repeat one-vessel CABG 2 years ago in the setting of aortic valve replacement with a #19 mm St. Jude bileaflet mechanical v ...
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Journal ArticleJ Heart Valve Dis · November 2013
Therapeutic ionizing radiation, such as that used in the treatment of Hodgkin's lymphoma, can cause cardiac valvular damage that may take several years to manifest as radiation-associated valvular heart disease. Treatment can be complicated by comorbid rad ...
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Journal ArticleRev Cardiovasc Med · 2012
Infective endocarditis (IE) is an infection of a heart valve or other cardiac structure at a site of endothelial damage. The definition has been also expanded to include infected cardiac devices. A variety of organ systems may be adversely affected in pati ...
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Journal ArticleCurr Treat Options Cardiovasc Med · December 2011
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Our approach to the management of the patient with a bicuspid aortic valve (BAV) takes several factors into consideration. First, is the dysfunction of the valve due to aortic stenosis (AS), aortic regurgitation (AR), or a combination of stenosis and regur ...
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Journal ArticleInt J Cardiol · August 4, 2011
BACKGROUND: Anemia is a marker of worsened clinical outcome in patients with heart failure from left ventricular dysfunction. Pulmonary hypertension often results in right ventricular dysfunction. Accordingly we sought to examine the association of hemoglo ...
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Journal ArticleJ Card Fail · April 2011
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OBJECTIVE: To examine the ability of vasodilator response to predict survival in a diverse cohort of patients with pulmonary hypertension (PH). PATIENTS & METHODS: A total of 214 consecutive treatment-naive patients referred for invasive PH evaluation were ...
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Journal ArticlePulm Med · 2011
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Pulmonary hypertension (PH) is the end result of a variety of diverse pathologic processes. The chronic elevation in pulmonary artery pressure often leads to right ventricular pressure overload and subsequent right ventricular failure. In patients with lef ...
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Journal ArticleJ Heart Valve Dis · November 2010
BACKGROUND AND AIM OF THE STUDY: Pulmonary hypertension frequently complicates mitral stenosis, with a subset of these patients exhibiting pressures well in excess of their mitral valve hemodynamics. The prevalence of this condition and its impact on clini ...
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Journal ArticleInt J Cardiovasc Imaging · August 2010
In this report, we describe a case of primary pericardial mesothelioma, which is an extremely rare tumor arising from mesothelial cells lining the pericardium and is associated with a dismal prognosis. ...
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Journal ArticleAm J Geriatr Pharmacother · February 2010
BACKGROUND: Ranolazine is increasingly being prescribed for the treatment of chronic stable angina. This report describes an adverse effect that may be related to ranolazine. CASE SUMMARY: A 77-year-old white man with chronic renal insufficiency was evalua ...
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Journal ArticleJ Heart Valve Dis · May 2009
BACKGROUND AND AIM OF THE STUDY: Pure annular dilation (PAD) is a recognized etiology of mitral regurgitation, yet few data exist to define the prognostic profile of this disorder relative to other etiologies, such as ischemia or myxomatous prolapse. METHO ...
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Journal ArticleIndian Heart J · 2009
Rheumatic Heart Disease (RHD) is well known to be an active inflammatory process which develops progressive calcification and leaflet thickening over time. The potential for statin therapy in slowing the progression of valvular heart disease is still contr ...
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Journal ArticleAm Heart J · November 2007
BACKGROUND: Training cardiovascular (CV) imaging specialists is becoming increasingly complex owing to rapidly emerging technological advances and the growing recognition that single modality training is inefficient and results in suboptimal education and ...
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Journal ArticleAm Heart J · September 2007
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BACKGROUND: Women and minorities traditionally have shown less use of diagnostic cardiac catheterization. We sought to determine whether mobile cardiac catheterization laboratories may increase the use of catheterization among women and minorities by bring ...
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Journal ArticleJ Heart Valve Dis · May 2006
BACKGROUND AND AIM OF THE STUDY: Inflammation may play a central role in the progression of stenotic valvular heart disease. Serum levels of matrix metalloproteinases (MMPs), markers of extracellular matrix (ECM) turnover and potential markers of active in ...
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Journal ArticleCurr Probl Cardiol · April 2006
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With infective endocarditis afflicting 15,000 patients each year and with a mortality rate that still hovers at almost 40%, the disease remains a very serious health problem. Surprisingly, the incidence has not declined over the last 30 years, and now with ...
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Journal ArticleRev Cardiovasc Med · 2006
With improved imaging techniques, such as cardiac magnetic resonance imaging and computed tomography, 2 unusual cardiomyopathies have been added to the differential diagnosis of nonischemic dilated cardiomyopathies. Ventricular noncompaction (VNC) classica ...
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Journal ArticleProc Natl Acad Sci U S A · October 11, 2005
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The mechanism by which hypoxia [low partial pressure of O(2) (pO(2))] elicits signaling to regulate pulmonary arterial pressure is incompletely understood. We considered the possibility that, in addition to its effects on smooth muscle, hypoxia may influen ...
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Journal ArticleAm Heart J · October 2005
BACKGROUND: Assessment of pulmonary vasodilator responsiveness is important in determining the prognosis and management of patients with pulmonary hypertension. Many patients, however, are already on vasodilators at the time of testing. It is unclear if th ...
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Journal ArticleRev Cardiovasc Med · 2005
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Adults with congenital heart disease (CHD) constitute a patient population that has grown rapidly, due to advances in diagnosis and treatment of children with CHD. Though ideally served by cardiologists with advanced training in congenital conditions, adul ...
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Journal ArticleJ Am Coll Cardiol · August 18, 2004
OBJECTIVES: Coronary angiograms obtained five years following revascularization were examined to assess the extent of compromise in myocardial perfusion due to failure of revascularization versus progression of native disease. BACKGROUND: The Bypass Angiop ...
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Journal ArticleAm J Cardiol · April 1, 2004
A prospective cohort of patients with mitral stenosis and no history of atrial arrhythmias showed no decrease in the incidence of atrial fibrillation (AF) after successful versus unsuccessful Inoue balloon percutaneous balloon mitral valve commissurotomy. ...
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Journal ArticleAm Heart J · February 2004
BACKGROUND: The late outcome of patients treated with atrial septal occluder devices remains incompletely defined. The purpose of this study was to assess the late outcome (range 4-7 years postprocedure) of patients in whom the Das AngelWings septal occlud ...
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Journal ArticleAm Heart J · December 2003
BACKGROUND: Markers of systemic inflammation including C-reactive protein (CRP) appear to predict morbidity and mortality in various clinical conditions. The presence of systemic inflammation and its impact on the procedural success of percutaneous balloon ...
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Journal ArticleSouth Med J · September 2003
Pericardial abscess is a rare complication of Staphylococcus aureus bacteremia. We report the case of a 40-year-old man with hepatitis C and liver cirrhosis who presented with high-grade fever and chest pain. Transthoracic echocardiography showed a pericar ...
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Journal ArticleCatheter Cardiovasc Interv · June 2003
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Using a prospectively collected database of patients undergoing cardiac catheterization, we sought to compare the outcomes of procedures performed by supervised physician assistants (PAs) with those performed by supervised cardiology fellows-in-training. O ...
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Journal ArticleAm Heart J · June 2003
BACKGROUND: Several techniques have been used to quantify the myocardium at risk, including measurement of regional ventricular function with contrast ventriculography and measurement of perfusion defect size with tomographic technetium-99m-sestamibi imagi ...
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Journal ArticleAnn Thorac Surg · March 2003
Severely elevated pulmonary vascular resistance (PVR) is a relative contraindication to orthotopic heart transplantation. A potential novel strategy to reverse elevated PVR may be implantation of a chronic left ventricular assist device with subsequent lef ...
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Journal ArticleCardiol Rev · 2003
We studied the relationship between mood and mood shift immediately before percutaneous coronary intervention (PCI) and 3 end points: total ischemic burden during PCI, adverse cardiac end points (ACE) after PCI, and death by 6-month follow up. Patients (n ...
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Journal ArticleJ Am Coll Cardiol · January 16, 2002
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OBJECTIVES: This study was designed to determine predictors of restenosis after successful percutaneous mitral commissurotomy (PMC) and its relationship to late clinical outcome. BACKGROUND: The restenosis rate after PMC and its relationship to late clinic ...
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Journal ArticleAm Heart J · November 2001
BACKGROUND: Patients undergoing percutaneous coronary intervention (PCI) for unstable coronary syndromes have substantial emotional and spiritual distress that may promote procedural complications. Noetic (nonpharmacologic) therapies may reduce anxiety, pa ...
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Journal ArticleAm J Cardiol · November 1, 2001
Percutaneous balloon mitral commissurotomy (PBMC) is now first-line therapy in patients with symptomatic mitral stenosis (MS) and favorable valve morphology. Unfortunately, the outcome of Medicare-aged patients undergoing this procedure has not previously ...
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Journal ArticleCatheter Cardiovasc Interv · September 2001
A basic understanding of the means by which images are acquired and processed in the cardiac catheterization laboratory should be a fundamental part of every cardiology training program. This review outlines the entire X-ray system step-by-step by followin ...
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Journal ArticleJ Am Soc Echocardiogr · April 2001
An association between left atrial spontaneous echocardiographic contrast (LASEC) and thromboembolic events has been recognized. However, the appearance of LASEC and the assessment of its intensity are gain dependent. To evaluate the relation between LASEC ...
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Journal ArticleJ Am Coll Cardiol · December 2000
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OBJECTIVES: We sought to compare the responses of patients with pulmonary hypertension from primary and secondary causes (PPH and SPH, respectively) to inhaled nitric oxide (iNO) in the cardiac catheterization laboratory. BACKGROUND: Pulmonary hypertension ...
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Journal ArticleChest · October 2000
Cardiac rhabdomyomas are extremely uncommon in the adult patient. We describe a previously healthy man who presented with ventricular arrhythmias resulting from a right ventricular, cardiac rhabdomyoma. Echocardiography, CT scanning, and MRI are recognized ...
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Journal ArticleKidney Int · April 2000
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BACKGROUND: Endothelin is a potent vasoconstrictor that has been implicated in the pathogenesis of radiocontrast nephrotoxicity. Endothelin antagonists may reduce the renal hemodynamic abnormalities following radiocontrast administration. METHODS: One hund ...
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Journal ArticleJ Am Coll Cardiol · April 2000
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OBJECTIVES: This study intended to determine the effect of varying degrees of lossy Joint Photographic Experts Group (JPEG) compression on detection of coronary angiographic features. BACKGROUND: Compression of digital coronary angiograms facilitates playb ...
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Journal ArticleEur Heart J · April 2000
OBJECTIVES: This study intended to determine the effect of varying degrees of lossy Joint Photographic Experts Group (JPEG) compression on detection of coronary angiographic features. Background Compression of digital coronary angiograms facilitates playba ...
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Journal ArticleClin Infect Dis · April 2000
Although the sensitivity and specificity of the Duke criteria for the diagnosis of infective endocarditis (IE) have been validated by investigators from Europe and the United States, several shortcomings of this schema remain. The Duke IE database contains ...
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Journal ArticleAm Heart J · January 2000
BACKGROUND: Evidence from numerous studies of coronary angiography show differences between observers' assessments of 15% to 45%. The implication of this variation is serious: If readings are erroneous, some patients will undergo revascularization procedur ...
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Journal ArticleJ Am Coll Cardiol · November 15, 1999
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OBJECTIVES: To determine the relative degree of revascularization obtained with bypass surgery versus angioplasty in a randomized trial of patients with multivessel disease requiring revascularization (Bypass Angioplasty Revascularization Investigation [BA ...
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Journal ArticleAm Heart J · October 1999
BACKGROUND: This study evaluated the correlation and variability between noninvasive and invasive measures of mitral stenosis severity before and after balloon mitral commissurotomy (BMC) in a large group of patients with symptomatic mitral stenosis. Facto ...
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Journal ArticleAm Heart J · October 1999
BACKGROUND: Patients presenting for coronary artery bypass graft (CABG) surgery may have concurrent asymptomatic aortic stenosis (AS) or aortic insufficiency (AI). This retrospective study was performed to evaluate outcomes in patients with aortic valve di ...
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Journal ArticleJ Thorac Cardiovasc Surg · May 1999
OBJECTIVE: The purpose of this study was to optimize selection criteria of biologic versus mechanical valve prostheses for aortic valve replacement. METHODS: Retrospective analysis was performed for 841 patients undergoing isolated, first-time aortic valve ...
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Journal ArticleCatheter Cardiovasc Interv · April 1999
We describe two unusual cases of hypoxemia after cardiac surgery due to intracardiac right-to-left shunting through a patent foramen ovale or atrial septal defect. The interatrial defects were successfully occluded by placement of a novel, transcather devi ...
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Journal ArticleAm J Cardiol · January 1, 1999
Clinical, echocardiographic, and cardiac catheterization data were evaluated in 263 patients with mitral stenosis who were undergoing balloon commissurotomy to determine the predictors of atrial rhythm and its effect on functional status. Conversion from a ...
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Journal ArticleAm J Cardiol · December 1, 1998
Left atrial v-wave amplitude has been associated with the presence and severity of chronic mitral regurgitation (MR) but it has not been evaluated for the detection of acute MR. We evaluated the left atrial v-wave amplitude of 205 consecutive patients with ...
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Journal ArticleAnn Thorac Surg · December 1998
BACKGROUND: The determinants of long-term outcome 15 years or more after porcine valve replacement are poorly documented. METHODS: A retrospective review was performed of patients undergoing valve replacement with standard Carpentier-Edwards aortic (n = 53 ...
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Journal ArticleCirculation · November 10, 1998
BACKGROUND: Percutaneous balloon mitral valvuloplasty and durable mitral prostheses have made the role of open mitral commissurotomy (OMC) uncertain. METHODS AND RESULTS: Results from the use of St Jude mitral valve replacement (SJMVR) were compared with t ...
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Journal ArticleCirculation · November 10, 1998
Background - Percutaneous balloon mitral valvuloplasty and durable mitral prostheses have made the role of open mitral commissurotomy (OMC) uncertain. Methods and Results - Results from the use of St Jude mitral valve replacement (SJMVR) were compared with ...
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Journal ArticleAm Heart J · October 1998
OBJECTIVES: This study evaluated the effect of aortic insufficiency on the correlation of pressure half-time-derived mitral valve area with each of 2 standards for mitral valve area (planimetry and cardiac catheterization) in a prospectively assembled coho ...
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Journal ArticleAnn Thorac Surg · June 1998
BACKGROUND: The Ross procedure has become an accepted and sometimes preferred alternative to mechanical aortic valve replacement. One criticism of the Ross procedure is that it may have a higher operative mortality, morbidity, and cost. Several groups have ...
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Journal ArticleJ Am Soc Nephrol · February 1998
Renal artery stenosis (RAS) is a relatively uncommon but important potentially reversible cause of renal failure. Little is known about the natural history of ischemic renal disease secondary to RAS. In previous reports, these researchers examined the inci ...
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Journal ArticleChest · January 1998
Pulmonary veno-occlusive disease (PVOD) is a rare form of pulmonary hypertension associated with fibrotic occlusion of the smaller pulmonary veins. Although vasodilator therapy is effective in many patients with primary pulmonary hypertension, the role of ...
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Journal ArticleAm J Med · January 1998
Superior vena cava syndrome (SVCS) is a distressing manifestation of benign or malignant disease obstructing return of blood flow through the superior vena cava (SVC). Treatment, often centering around management of the underlying illness, may be slow in r ...
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Journal ArticleCathet Cardiovasc Diagn · September 1997
We present a novel technique employing biplane cineangiography with simultaneous left coronary and pulmonary angiography to define the anomalous course of the left main coronary artery when it originates from the right sinus of Valsalva. These biplane cine ...
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Journal ArticleCirculation · August 19, 1997
BACKGROUND: Development of the "all-digital" cardiac catheterization laboratory has been slowed by substantial computer archival and transfer requirements. Lossy data compression reduces this burden but creates irreversible changes in images, potentially i ...
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Journal ArticleAm J Cardiol · August 1, 1997
This study evaluates right ventricular (RV) and pulmonary function during exercise in adults with congenital heart disease (CHD). Thirty-one patients with CHD involving the right side of the heart underwent symptom-limited bicycle exercise testing with sim ...
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Journal ArticleAm J Cardiol · July 15, 1997
Twenty-nine patients with moderate mitral stenosis and 29 age-matched normal controls underwent symptom-limited upright bicycle exercise testing with simultaneous hemodynamic monitoring. Exercise tolerance in the mitral stenosis group was found to be limit ...
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Journal ArticleProg Cardiovasc Dis · 1997
Balloon aortic valvuloplasty is a percutaneous, therapeutic option for patients with severe aortic stenosis, yet the effectiveness of this procedure is dependent on the morphology of the stenotic aortic valve and the respective mechanism of dilation. In yo ...
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Journal ArticleACC Current Journal Review · January 1, 1997
The studies that have addressed combined CABG and AVR in those with significant coronary artery disease and asymptomatic aortic valve disease offer important insight into the management of this subset of patients. From the information available, we can con ...
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Journal ArticleCardiology Review · December 1, 1996
In this study of 165 elderly patients with severe symptomatic aortic valve stenosis treated with balloon valvuloplasty, long-term event-free and actuarial survival was poor regardless of symptoms at presentation and resembled the natural history of untreat ...
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Journal ArticleCathet Cardiovasc Diagn · August 1996
A 27-yr-old woman with recurrent episodes of hemoptysis (and hematemesis due to esophageal varices) was found to have unilateral pulmonary vein atresia. Reversed flow in the left pulmonary artery, a finding highly suggestive of this rare congenital anomaly ...
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Journal ArticleAm J Cardiol · July 15, 1996
Digital coronary angiographic techniques are now widely used in many cardiac catheterization laboratories. However, the full potential of digital imaging technology remains to be achieved because of its enormous storage and exchange requirements. Compressi ...
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Journal ArticleAnn Thorac Surg · July 1996
A number of patients with complex congenital heart disease who were initially palliated with a classic Glenn shunt subsequently underwent modified Fontan procedures. This report discusses the operative management of complete occlusion of right atrial-to-ri ...
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Journal ArticleJ Heart Lung Transplant · May 1996
Occlusion of the pulmonary artery anastomosis is an uncommon early complication of lung transplantation which necessitates emergency surgical revision. Percutaneous correction of such a complication has not been previously reported. We report a patient who ...
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Journal ArticleAm J Cardiol · February 15, 1996
With use of new Duke criteria, 405 episodes of suspected endocarditis were previously classified as "definite," "possible," or "rejected" endocarditis. To determine the negative predictive value of the Duke clinical criteria for the classification of suspe ...
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Journal ArticleProceedings of SPIE - The International Society for Optical Engineering · December 1, 1995
A cardiology review station for clinical use has been developed which can decompress, zoom, and display full resolution JPEG- encoded cardiac angiograms and echocardiograms in real-time (30 frames/second). The review station is installed in a network which ...
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Journal ArticleJ Am Coll Cardiol · November 15, 1995
OBJECTIVES: This study sought to determine the long-term outcome of adult patients undergoing percutaneous balloon aortic valvuloplasty. BACKGROUND: Percutaneous balloon aortic valvuloplasty has been offered as an alternative to aortic valve replacement fo ...
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Journal ArticleAm J Cardiol · September 15, 1995
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EF in patients with aortic stenosis and reduced EF who underwent aortic valve replacement did not improve by 1 week postoperatively despite rectification of afterload mismatch. By 6 months, however, EF significantly improved without any further change in v ...
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Journal ArticleCirculation · August 15, 1995
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BACKGROUND: Although serotonin has been postulated as an etiologic agent in the development of carcinoid heart disease, no direct evidence for different ambient serotonin levels in cardiac and noncardiac patients has been reported to date. METHODS AND RESU ...
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Journal ArticleAm Heart J · June 1995
The development of hypotension during various exercise stress tests has been correlated with the presence of multivessel coronary artery disease and impaired left ventricular contractility. Hypotension may also occur during dobutamine stress echocardiograp ...
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Journal ArticleCathet Cardiovasc Diagn · May 1995
Historically, the right heart was viewed as less important than the left heart in the maintenance of normal overall hemodynamic performance. However, there is now considerable evidence that emphasizes the significance of intact right ventricular (RV) funct ...
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Journal ArticleAm J Cardiol · March 1, 1995
The cardiac valvular surgical experience of patients in the Duke Carcinoid Database was reviewed to assess operative outcome. Of the 604 patients in the database, 19 patients with carcinoid heart disease were identified by cardiac catheterization or echoca ...
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Journal ArticleCathet Cardiovasc Diagn · March 1995
Mitral incompetence (MR) is a complication of balloon mitral valvuloplasty. There are few reports of long-term outcome. We believe this is the first report in the literature of complete resolution during follow-up of severe mitral regurgitation resulting f ...
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Journal ArticleAm Heart J · February 1995
The accuracy and precision of a fully automated quantitative coronary angiography (QCA) algorithm for use in a cineless environment were determined in phantom studies and in an in vivo canine preparation. Imaging studies of 118 coronary segments in six ane ...
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Journal ArticleAm J Cardiol · January 1, 1995
Transesophageal echocardiography and diagnostic cardiac catheterization were performed in 36 patients with symptomatic mitral stenosis to assess the incidence and significance of systolic flow reversal in the pulmonary veins. Mitral regurgitation was grade ...
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Journal ArticleCathet Cardiovasc Diagn · January 1995
Seven patients underwent attempted low pressure balloon dilation of stenotic conduits or homografts from right ventricle to pulmonary artery (n = 5), in the aortic valve position (n = 1), or from right atrium to left pulmonary artery (n = 1). In the right ...
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Journal ArticleCirculation · November 1, 1994
Background: Percutaneous balloon aortic valvuloplasty is limited by a high risk of procedural morbidity, transient clinical benefit, and a high restenosis rate. The management of patients with symptomatic aortic valve restenosis after percutaneous balloon ...
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Journal ArticleAm J Cardiol · October 15, 1994
The purpose of this study was twofold: (1) to determine interobserver variability of echocardiographic characteristics of vegetations in patients with infective endocarditis, and (2) to assess the value of these vegetation characteristics in predicting emb ...
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Journal ArticleInt J Card Imaging · September 1994
The clinical application of quantitative methods for coronary arteriography remains limited, due in large part to the absence of a suitable replacement for cinefilm as the procedure record. The extension to the clinical environment of the validated objecti ...
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Journal ArticleChest · July 1994
Relief of superior vena cava (SVC) syndrome due to non-neoplastic mediastinal disease presents a formidable challenge. Long-term patency of surgically created bypass grafts has been poor, and the morbidity associated with these procedures is substantial. W ...
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Journal ArticleN C Med J · April 1994
Adult patients with congenital heart disease present complex problems that require individualized management. Unfortunately, few physicians who care for adults with congenital heart disease have received adequate specific training to deal with their proble ...
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Journal ArticleAm J Med · March 1994
PURPOSE: This study was designed to develop improved criteria for the diagnosis of infective endocarditis and to compare these criteria with currently accepted criteria in a large series of cases. PATIENTS AND METHODS: A total of 405 consecutive cases of s ...
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Journal ArticleCirculation · February 1994
BACKGROUND: To identify predictors of long-term outcome after balloon aortic valvuloplasty, we analyzed data on 674 adults (mean age, 78 +/- 9 years; 56% were women) undergoing this procedure at 24 clinical centers who had a mean initial increase in aortic ...
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Journal ArticleCathet Cardiovasc Diagn · 1994
Recent randomized studies have demonstrated that percutaneous transvenous mitral commissurotomy (PTMC) has similar efficacy compared to surgical commissurotomy. Compared with surgery, PTMC is associated with shorter hospital stays, reduced patient discomfo ...
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Journal ArticleAm J Cardiol · December 1, 1993
To determine the usefulness of dobutamine stress echocardiography for detecting restenosis after percutaneous transluminal coronary angioplasty, the results of coronary arteriography and dobutamine stress echocardiography were compared in 103 patients 6 mo ...
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Journal ArticleAnn Thorac Surg · December 1993
To determine the optimal role for percutaneous balloon mitral valvuloplasty or open mitral commissurotomy, the outcome of 164 consecutive patients undergoing either percutaneous balloon mitral valvuloplasty, open mitral commissurotomy, or mitral valve repl ...
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Journal ArticleCardiol Clin · November 1993
The prevalence, anatomy and physiology, clinical manifestations, laboratory findings, and management of patients with aortic/mitral obstruction and coarctation of the aorta are assessed. Subaortic stenosis reviewed includes discreet membranous and tunnel s ...
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ConferenceProceedings of SPIE - The International Society for Optical Engineering · September 8, 1993
An economical and practical digital solution for the replacement of 35mm cinefilm as the archive media in the cardiac x-ray imaging environment has remained lacking to date due to the demanding requirements of high capacity, high acquisition rate, high tra ...
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Journal ArticleAm J Cardiol · June 1, 1993
Most reported studies of percutaneous balloon valvuloplasty in adults with acquired mitral stenosis have used patients with severely stenosed valves. The risks and benefits of valvuloplasty were examined in a multicenter registry of patients to determine w ...
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Journal ArticleChest · April 1993
Endomyocardial breast cancer metastases are extremely rare and have previously been diagnosed antemortem only through median sternotomy and cardiotomy. We report a case of endomyocardial breast cancer metastasis which was diagnosed antemortem by transvenou ...
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Journal ArticleAm J Cardiol · March 15, 1993
Necropsy examinations and epicardial ultrasound studies have suggested that atherosclerotic coronary arteries undergo compensatory enlargement. This increase in vessel size may be an important mechanism for maintaining myocardial blood flow. It also is of ...
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Journal ArticleCathet Cardiovasc Diagn · March 1993
Currently percutaneous transvenous mitral commissurotomy (PTMC) is performed by most operators using stepwise inflation of the Inoue balloon beginning at a small diameter and increasing size by a sequence of inflations to nominal diameter. The effect of ba ...
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Journal ArticleAm J Cardiol · January 15, 1993
Selective, coronary arteriographic, catheter-based, intravascular ultrasound images were obtained to determine the presence and extent of angiographically undetected or underestimated left main (LM) coronary arterial narrowing in patients receiving coronar ...
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Journal ArticleCirc Res · November 1992
To investigate complementarity and competitiveness between the intrinsic and extrinsic components of the total left ventricular systolic load, hemodynamic data from 18 elderly subjects with severe aortic stenosis were analyzed before and after balloon dila ...
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Journal ArticleAnn Thorac Surg · August 1992
Concurrent aortic stenosis and patent ductus arteriosus are not infrequent in children but are rare in adults. An adult case is described with diagnosis by cardiac catheterization and magnetic resonance imaging and with management by combined aortic valve ...
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Journal ArticleCirculation · July 1992
BACKGROUND: Mitral restenosis after surgical mitral commissurotomy often occurs within 5-15 years, necessitating a repeat procedure. Balloon mitral commissurotomy (BMC) has been advocated as an alternative to repeat surgery for mitral restenosis. METHODS A ...
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Journal ArticleAm Heart J · July 1992
Clinical trials with the Inoue mitral valvotomy balloon have recently begun in the United States. We assessed the effects of 17 demographic, echocardiographic, procedural, and hemodynamic variables on the immediate results, complications, and short-term fo ...
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Journal ArticleJ Am Coll Cardiol · July 1992
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The utility of ergonovine testing for coronary artery spasm was assessed in 3,447 patients with angiographically insignificant (less than 50% diameter stenosis) or no coronary artery disease. No patients clinically had Prinzmetal's variant angina. Overall, ...
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Journal ArticleAm J Cardiol · June 15, 1992
Although both catheterization and Doppler measures of valvular stenosis severity have been validated, each has specific advantages and limitations, particularly in the setting of balloon valvuloplasty. Invasive valve area and mean pressure gradient recorde ...
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Journal ArticleJ Am Coll Cardiol · June 1992
The end-systolic pressure-volume relation, the relation between stroke work and end-diastolic volume, termed the preload recruitable stroke work relation, and the relation between the peak of the first derivative of left ventricular pressure (dP/dtmax) and ...
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Journal ArticleJ Am Soc Nephrol · May 1992
The purposes of this study were to determine the prevalence of angiographically significant renal artery stenosis in a patient population referred for diagnostic cardiac catheterization and to develop a model that predicts the highest-risk subset of patien ...
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Journal ArticleCathet Cardiovasc Diagn · April 1992
Cor triatriatum, although rare in adults, is often associated with anomalous pulmonary venous return. Accurate diagnosis of the pulmonary venous return and its anatomic connections is essential in planning proper surgical correction. This case illustrates ...
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Journal ArticleChest · March 1992
We report a 52-year-old patient with severe mitral stenosis who developed new onset atrial fibrillation, low output congestive heart failure and fulminant ischemic hepatic failure with subsequent severe coagulopathy. Percutaneous mitral valvotomy resulted ...
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Journal ArticleCathet Cardiovasc Diagn · February 1992
Coronary angiography continues to be the pivotal study in the diagnosis and treatment of ischemic cardiac disease. Although angiographic equipment and imaging techniques have advanced over the past three decades, the analysis of coronary angiograms, by vis ...
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ConferenceProceedings - Computers in Cardiology, CIC 1992 · January 1, 1992
We have developed a flexible and powerful coronary anatomy classification system which can be applied to the development and evaluation of qualitative and quantitative methods for assessing myocardium in jeopardy on the basis of the severity and location o ...
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ConferenceProceedings - Computers in Cardiology, CIC 1992 · January 1, 1992
An expert panel Task Force of the AHA/ACC reported that determination of lesion morphology was predictive of adverse events after diagnostic/interventional procedures. To date, the classification system proposed by the Task Force has not been routinely use ...
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Journal ArticleAm J Cardiol · January 1, 1992
The time course of left ventricular (LV) filling and LV diastolic performance were examined in 27 consecutive patients in sinus rhythm before and acutely after balloon mitral valvotomy (BMV). The mitral valve area acutely increased from 1.1 +/- 0.3 to 2.1 ...
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Journal ArticleJ Magn Reson Imaging · 1992
The accuracy and reproducibility of cardiac ejection fraction (EF) measurements based on cine magnetic resonance (MR) imaging, radionuclide multigated acquisition (MUGA) blood pool imaging, and angiographic ventriculography were evaluated by comparing them ...
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Journal ArticleCirculation · January 1992
BACKGROUND: The effect of valve deformity and patient age adversely affect the results of percutaneous transvenous mitral commissurotomy (PTMC) with conventional balloons. METHODS AND RESULTS: These factors were characterized after PTMC with the Inoue ball ...
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Journal ArticleAm J Cardiol · December 1, 1991
Baseline echocardiographic data in 680 adults (mean age 78 years) undergoing balloon aortic valvuloplasty at 24 medical centers were analyzed to describe the degree of outflow obstruction in patients with symptomatic aortic stenosis. Maximal aortic jet vel ...
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Journal ArticleCirculation · December 1991
BACKGROUND: Percutaneous balloon aortic valvuloplasty has been used as a therapeutic option for relief of valvular stenosis. This study describes patients undergoing initial percutaneous aortic balloon valvuloplasty enrolled in the National Heart, Lung, an ...
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Journal ArticleCirculation · November 1991
Featured Publication
It is evident that the practice of cardiac catheterization has undergone, and continues to undergo, marked change. Most prominent are the recent very rapid proliferation of catheterization laboratories in general and the development of newer types of cathe ...
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Journal ArticleAm J Cardiol · November 1, 1991
Using catheter outer diameter as a scaling device, quantitative coronary arteriography allows the precise and objective measurement of change in absolute dimensions of coronary arteries after mechanical or pharmacologic intervention. Because of variable de ...
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Journal ArticleCathet Cardiovasc Diagn · September 1991
Valve repair and calcium debridement in patients with calcific aortic stenosis, using the Cavitron Ultrasonic Surgical Aspirator (CUSA), results in a reduction in the aortic valve gradient while potentially avoiding long-term problems inherent to prostheti ...
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Journal ArticleAm J Cardiol · July 1, 1991
Balloon aortic valvuloplasty (BAV) has been a therapeutic alternative treatment for severe symptomatic aortic stenosis. Previous studies have been unable to predict 1-year outcome because of limited acute and follow-up clinical, invasive and echocardiograp ...
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Journal ArticleComputers in Cardiology · May 1, 1991
A multi-user system capable of assessing the changes induced from interventional procedures such as coronary angioplasty (PTCA) is assembled using quantitative coronary angiography coupled with the visual assessment of twenty morphological descriptors as i ...
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Journal ArticleComputers in Cardiology · May 1, 1991
A method for measuring regional variation in coronary blood flow has been developed using image processing techniques applied to sequences of digital coronary angiograms. A series of digital subtraction angiography images is used as a basic data set to for ...
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Journal ArticleAm J Cardiol · April 15, 1991
Validation of catheter-based intravascular ultrasound imaging has been based on comparisons with histology and digital angiography, each of which may have limitations in the assessment of arterial size and morphology. External, high-frequency ultrasound ca ...
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Journal ArticleJ Am Coll Cardiol · April 1991
Featured Publication
The results of recatheterization were assessed in a select group of 95 patients enrolled in the Mansfield Scientific Aortic Valvuloplasty Registry to determine whether any procedural or patient-related variables at baseline predicted either initial immedia ...
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Journal ArticleTrends Cardiovasc Med · March 1991
The use of nonionic contrast agents during cardiac catheterization decreases the incidence of both major and minor cardiovascular complications when compared with ionic contrast. Hemodynamic and electrophysiologic effects are less profound especially in pa ...
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Journal ArticleCirc Res · March 1991
The effect of the radiographic contrast agents, iopamidol and diatrizoate, on fibrin assembly and structure as well as platelet surface charge was studied. Increasing the iopamidol concentration from 0 to 4.5 mM prolongs the fibrin gelation time from 20 to ...
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Journal ArticleMedicaMundi · January 1, 1991
This article describes the application of quantitative cardiac analysis in a high volume clinical environment. Computerized evaluation is applied for measurement of coronary artery stenoses, and for determination of global and regional ventricular function ...
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Journal ArticleCathet Cardiovasc Diagn · December 1990
A 36-year-old woman with congenital pulmonary valve stenosis developed the rare complication of endocarditis of the valve. After successful sterilization of the valve, the patient underwent percutaneous balloon pulmonic valvuloplasty at a later date. The p ...
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Journal ArticleProceedings of SPIE - The International Society for Optical Engineering · December 1, 1990
The increased application of digital imaging techniques to diagnostic cardiology requires the resolution of several remaining problems involving the transmission, display and storage of clinical image data. A Digital Imaging Laboratory is being assembled f ...
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Journal ArticleJ Am Coll Cardiol · November 1990
Although impaired ventricular function has been shown to improve after aortic valve replacement, there are few data on hemodynamic changes after balloon aortic valvuloplasty based on follow-up catheterization. Of 71 patients surviving 6 months after balloo ...
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Journal ArticleJ Am Coll Cardiol · October 1990
To evaluate the effectiveness and cost of low osmolarity, nonionic contrast agents for cardiac angiography, 443 patients were randomized to receive either iopamidol or diatrizoate. All adverse events that occurred within 24 h of the procedure were recorded ...
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Journal ArticleJ Am Coll Cardiol · October 1990
To evaluate acute and follow-up changes in left ventricular diastolic performance, simultaneous digital left ventriculography and micromanometry were performed in 49 patients undergoing aortic balloon valvuloplasty. All patients improved symptomatically af ...
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Journal ArticleCathet Cardiovasc Diagn · September 1990
Retrograde crossing of valvular aortic stenosis can be challenging even to experienced angiographers. In 446 of 447 consecutive patients with aortic stenosis catheterized during the past 3 years, a technique using a standard Judkins right coronary catheter ...
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Journal ArticleJ Am Coll Cardiol · September 1990
The accuracy of catheter-based intravascular ultrasonography to define luminal size in humans in vivo and its sensitivity to describe lesion morphology have not been previously reported. Vessel diameter, cross-sectional area and lesion characteristics asse ...
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Journal ArticleAm J Cardiol · August 1, 1990
To evaluate early and late hemodynamics after aortic valvuloplasty, 17 patients underwent first-pass radionuclide angiocardiography with simultaneous high-fidelity micromanometer pressure before, 10 minutes after and 6 months after aortic valvuloplasty. Pr ...
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Journal ArticleAm J Cardiol · July 1, 1990
The capability of dynamic gradient-refocused magnetic resonance imaging (cine MRI) to detect, localize and functionally assess acute myocardial infarction (AMI) in 25 patients at a mean time interval of 7 days after AMI was evaluated. Fifteen asymptomatic ...
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Journal ArticleAm J Cardiol · June 15, 1990
The incidence of major complications associated with nonionic contrast media has not been defined in a large study. Accordingly, cardiovascular complications, especially thrombotic events, were prospectively evaluated in 8,517 consecutive patients undergoi ...
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Journal ArticleJ Am Coll Cardiol · June 1990
Because earlier ambulation and discharge after cardiac catheterization may result in the increased utilization of outpatient facilities, a prospective five center clinical pilot trial assessing the safety and outcome of early ambulation after routine left ...
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Journal ArticleAm J Cardiol · May 15, 1990
To evaluate the acute changes in left ventricular (LV) performance before and immediately after percutaneous aortic valvuloplasty, 25 patients underwent first-pass radionuclide angiocardiography for construction of pressure-volume loops. Simultaneously, hi ...
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Journal ArticleJ Am Coll Cardiol · April 1990
To assess the relation of quantitative measures of coronary stenoses to the development of exercise-induced regional wall motion abnormalities, 34 patients with isolated, single vessel coronary artery lesions and normal wall motion at rest underwent exerci ...
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Journal ArticleJ Am Coll Cardiol · March 15, 1990
Intravascular ultrasound images were employed to evaluate aortic coarctation before and after balloon angioplasty. Measurements obtained with use of an ultrasound imaging catheter correlated well with measurements made with digital aortography, both in the ...
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Journal ArticleJ Am Coll Cardiol · February 1990
To determine the feasibility and cost-saving potential of substituting outpatient for inpatient cardiac catheterization, 986 consecutive procedures were studied at a large referral hospital. Patients were classified prospectively as to their eligibility fo ...
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Journal ArticleAm J Cardiol · January 1, 1990
Featured Publication
Although balloon aortic valvuloplasty usually results in acute hemodynamic improvement, recurrent symptoms often occur within several months. The current study was designed to determine whether clinical characteristics, including invasive hemodynamic param ...
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Journal ArticleAm Heart J · January 1990
To evaluate the serial changes in right and left ventricular performance after percutaneous aortic balloon valvuloplasty, 15 patients, mean age 75 +/- 18 years, and in New York Heart Association (NYHA) class III, were studied with first-pass radionuclide a ...
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Journal ArticleAm Heart J · November 1989
In order to validate the measurement of pressure-volume loops and stroke work in humans, simultaneous digital subtraction ventriculography (DSA) and first-pass radionuclide angiocardiography (RNA) coupled with high-fidelity micromanometer left ventricular ...
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Journal ArticleAm J Cardiol · June 1, 1989
Doppler mitral flow indexes and their relation to invasively measured hemodynamic diastolic indexes were assessed in 13 patients with isolated aortic stenosis (AS), and compared to Doppler indexes in 10 normal subjects matched for age, heart rate, left ven ...
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Journal ArticleCirculation · April 1989
Eighteen patients with isolated left bundle branch block (LBBB) were compared with 10 normal control subjects. Apexcardiograms, phonocardiograms, electrocardiograms, two-dimensional and dual M-mode echocardiograms, and radionuclide ventriculograms (RNV) we ...
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Journal ArticleAm J Cardiol · March 1, 1989
The serial changes in aortic regurgitation (AR) after balloon aortic valvuloplasty have not been quantitatively evaluated. This study assessed the degree of AR by quantitative and qualitative techniques before and immediately after aortic valvuloplasty. Di ...
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Journal ArticleAm J Cardiol · February 15, 1989
To determine the association of qualitative and quantitative measurements of the myocardial infarct-related coronary narrowing with subsequent recurrent ischemia/reocclusion after successful thrombolysis, 47 patients treated with high-dose (150 mg) tissue ...
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Journal ArticleAm Heart J · February 1989
The relationship between dynamic changes in aortic valve gradient and left ventricular ejection performance in the early period after successful percutaneous aortic valvuloplasty has not been described in detail. Accordingly 20 adult patients with severe s ...
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Journal ArticleAtherosclerosis · February 1989
Reports on vascular pathology post-PTCA in both human and animal coronary vessels have revealed medial and intimal cracks and tears, thrombus formation, platelet accumulation, and loss of endothelial cells. The extent and type of damage can currently be as ...
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Journal ArticleN Engl J Med · January 19, 1989
Experimental studies have suggested that nonionic contrast agents are less nephrotoxic than ionic contrast agents. To examine the relative nephrotoxicity of the two types of agents, we randomly assigned 443 patients to receive either iopamidol (nonionic) o ...
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Journal ArticleAnn Intern Med · January 15, 1989
STUDY OBJECTIVE: To determine the incidence of cardiovascular and renal toxicity of a nonionic contrast agent when used for cardiac catheterization, and to assess the value of electrolytes and urinalysis results as predictors of nephropathy induced by a co ...
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Journal ArticleAm J Cardiol · September 1, 1988
To examine the effects of digital image acquisition mode and subtraction techniques on the results of coronary stenosis quantitation, 100 discrete lesions from 45 patients undergoing routine diagnostic angiography were analyzed in each of 3 image types: di ...
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Journal ArticleAm Heart J · June 1988
The dynamics of the delayed accentuated mitral component (M1) of the first heart sound and the MOS were studied in 11 patients with mitral stenosis of varying severity. Echophonocardiographic (M-mode and 2D) studies were performed with analysis of LA dimen ...
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Journal ArticleAnn Intern Med · April 1988
STUDY OBJECTIVE: To prospectively investigate the evidence for embolic phenomena associated with percutaneous mitral and aortic valvuloplasty. DESIGN: Prospective, consecutive case series before and after balloon valvuloplasty. SETTING: Referral center hos ...
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Journal ArticleJ Am Coll Cardiol · March 1988
The hemodynamics of the supine and upright exercise response in 16 symptomatic women with mitral valve prolapse (Group I) was compared with that in 8 asymptomatic normal control women (Group II). All subjects had supine and upright echocardiography and pho ...
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Journal ArticleCathet Cardiovasc Diagn · 1988
The effect of intracoronary papaverine administration on epicardial coronary arterial diameter was examined in 18 male patients. Coronary-artery cineangiograms were acquired with a power injector before intervention, 20 sec after intracoronary saline (cont ...
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Journal ArticleCathet Cardiovasc Diagn · 1988
To assess the effect of rapid preload reduction on left ventricular performance in nonischemic cardiomyopathy, 11 patients were studied during inferior vena caval (IVC) balloon occlusion. Five developed sustained pulsus alternans. During pulsus alternans, ...
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Journal ArticleRadiology · December 1987
The high-energy myocardial phosphate metabolism of four patients with acute anterior myocardial infarction after coronary angioplasty and drug therapy was evaluated with cardiac-gated phosphorus magnetic resonance (MR) depth-resolved surface coil spectrosc ...
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Journal ArticleAm J Cardiol · June 1, 1987
The accuracy of coronary artery diameter determination by digital angiography was assessed by imaging 39 coronary segments of excised dog and human hearts and comparing these segments with pathologic sections 0.76 to 3.31 mm in luminal diameter. Digital im ...
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Journal ArticleNucl Med Commun · June 1987
Ventricular filling rates derived from radionuclide angiographic (RNA) time-activity curves are commonly expressed as normalized values. The assumption that normalized filling rates have a relationship to the actual filling rates was tested. RNA and contra ...
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Journal ArticleAJR Am J Roentgenol · May 1987
Cine MR imaging provides tomographic images of the heart with both high spatial and high temporal resolution. As many as 32 images per cardiac cycle can be acquired with up to four separate anatomic slices and a total imaging time of 128 cardiac cycles. En ...
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Journal ArticleAm J Cardiol · April 15, 1987
To investigate the safety and efficacy of inferior vena caval (IVC) balloon occlusion for preload alteration in humans, 13 patients with dilated cardiomyopathy were studied before and during repeated (total of 78) IVC occlusions. Left and right ventricular ...
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Journal ArticleJ Am Coll Cardiol · April 1987
To investigate the relation between left ventricular chamber dynamics in humans and the quantitative analysis of the histologic and biochemical characteristics of left ventricular endomyocardial biopsy material, 15 patients with a wide range of ventricular ...
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Journal ArticleClin Cardiol · March 1987
Twenty-one normal young male subjects underwent resting and exercise (bicycle) radionuclide angiography in the full supine and 70 degrees upright tilt positions in order to examine the effects of position on left ventricular size and performance, hemodynam ...
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Journal ArticleClin Nucl Med · February 1987
A case of right ventricular aneurysm due to coronary artery disease in a 69-year-old male with no prior history of surgery or chest trauma is reported. The presence of the aneurysm was diagnosed by gated radionuclide angiography and confirmed by contrast a ...
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Journal ArticleJ Thorac Cardiovasc Surg · November 1986
The internal mammary artery has become the coronary bypass graft of choice in recent years because of enhanced long-term patency. Along with this trend, sequential, bilateral, and free mammary grafts have been employed more frequently in an effort to maxim ...
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Journal ArticleAm J Cardiol · September 1, 1986
To investigate whether gated radionuclide angiographic phase imaging is useful for visually displaying the origin of ventricular premature complexes (VPCs), 82 patients were studied by gating only VPCs. The VPC "origin" by the scintigraphic method was defi ...
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Journal ArticleJ Clin Invest · October 1985
The effects of intermittent infusions of dobutamine were studied in young normal male subjects during a period of bedrest deconditioning to determine whether this synthetic catechol affects physical conditioning processes in humans. 24 volunteers were plac ...
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Journal ArticleAm Heart J · September 1985
It is generally accepted that upright posture decreases preload and afterload, which could alter left ventricular (LV) performance. It is not known if changes occurring with acute standing persist after prolonged ambulatory activity (amb-act). In seven nor ...
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Journal ArticleCirculation · October 1984
This study was designed to investigate the potential role of radionuclide angiographic phase imaging in defining ventricular pacing sites. Twenty patients were paced from multiple right ventricular and left ventricular sites. Ten patients had both normal w ...
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Journal ArticleAm J Cardiol · April 1, 1984
It has been suggested that the effect of a premature ventricular contraction (PVC) on left ventricular (LV) function depends on the site of origin of the PVC, and that the subsequent impairment of LV performance during a PVC may be more pronounced if basel ...
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Journal ArticleAm J Cardiol · February 1, 1984
This study was designed to more clearly define the relation between various invasive hemodynamic measurements and left ventricular (LV) timing intervals, ejection rate and filling rate derived from the radionuclide angiographic volume curve. Twenty-eight p ...
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Journal ArticleInt J Clin Pharmacol Res · 1984
Eighteen patients with congestive heart failure were studied in a double-blind, randomized, placebo-controlled withdrawal trial to evaluate the effectiveness of chronic oral amrinone therapy when added to conventional heart failure therapy. All patients re ...
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Journal ArticleAm J Cardiol · August 1983
Amrinone, 100 mg orally every 8 hours, was administered to 13 patients with moderate-to-severe congestive heart failure (CHF) for 1 month on an outpatient basis to determine the beneficial and undesirable effects of this new cardioactive agent in this clin ...
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Journal ArticleCirculation · April 1983
This study was designed to validate the use of combined invasive and noninvasive methods in assessing serial pressure-volume relations in man. Ten patients undergoing cardiac catheterization were studied with simultaneous intracardiac micromanometer pressu ...
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Journal ArticleCancer Treat Rep · April 1983
Mitoxantrone is a synthetic anthraquinone that was developed through the doxorubicin analog program in hopes of retaining anticancer activity with less cardiotoxicity. This study evaluated 18 patients receiving mitoxantrone with serial noninvasive tests of ...
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Journal ArticleChest · February 1983
Patients with ECG nonischemic ST segment elevation were prospectively studied to determine the accuracy of the initial ECG diagnoses. Evaluations were made of 131 consecutive patients by serial clinical, ECG, and echocardiography to establish a diagnosis. ...
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Journal ArticleAm J Cardiol · October 1982
Eighty men (group A) with clinical coronary artery disease underwent coronary angiography regardless of symptoms and previous therapy because they had a positive treadmill exercise test in stage I or II of the Bruce protocol. Thirty-four other men (group B ...
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Journal ArticlePacing Clin Electrophysiol · January 1982
This study assesses the clinical and electrode complications associated with the use of the epicardial screw-on electrode technique for permanent ventricular pacing. The records of 114 consecutive patients who received screw-on epicardial electrodes were a ...
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Journal ArticleAnn Thorac Surg · February 1981
Myocardial bridges have been associated with clinical and metabolic evidence of ischemia, although the mechanism for this is unclear. We measured coronary blood flow and segmental function at different heart rates prior to and after release of a myocardial ...
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Journal ArticleCirculation · October 1980
We evaluated a patient who had transient episodes of hypotension with clinical and laboratory features apparently distinct from previously recognized disorders of vasomotor regulation. In between his abrupt attacks of hypotension, the patient is asymptomat ...
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Journal ArticleN Engl J Med · November 15, 1979
To examine the risk of ventricular fibrillation in patients with the Wolff-Parkinson-White syndrome, we compared patients who had this syndrome and a history of ventricular fibrillation related to preexcitation with patients who had the syndrome without th ...
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Journal ArticleCirculation · February 1979
The electrophysiologic effects of intravenously administered disopyramide (2 mg/kg) on three parameters of sinus node function were examined in 16 symptomatic patients with sinus node dysfunction. Based on their ECG data before study, patients were subdivi ...
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Journal ArticleCirculation · August 1977
The effect of digitalis in 21 patients with Wolff-Parkinson-White syndrome was anlayzed with respect to the ventricular response during atrial fibrillation and antegrade and retrograde refractory periods of accessory pathways. Digitalis shortened the cycle ...
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Journal ArticleCirculation · January 1977
Thirty-three patients with Wolff-Parkinson-White syndrome were studied electrophysiologically before and after administration of intravenous procainamide and oral quinidine sulfate. Procainamide prolonged the shortest R-R (SRR) interval between two consecu ...
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