Scholars@Duke
William Ferris Malcolm

William Ferris Malcolm

Professor of Pediatrics
Pediatrics, Neonatology
william.malcolm@duke.edu
Box 102509 DUMC, Durham, NC 27710
2400 Pratt St, Durham, NC 27705

Selected Publications

Hydrocortisone in Preterm Infants and School-Age Functional Outcomes: Follow-Up of a Randomized Clinical Trial.

Journal Article JAMA Pediatr · December 8, 2025 IMPORTANCE: Bronchopulmonary dysplasia (BPD) is the most common in-hospital morbidity of prematurity, associated with significant long-term medical and neurodevelopmental sequelae and health resource utilization. The Neonatal Research Network (NRN) Hydroco ... Full text Link to item Cite

Outcomes of extremely preterm infants exposed to prolonged prelabor rupture of membranes before 24 weeks of gestation.

Journal Article Am J Obstet Gynecol · August 2025 BACKGROUND: Preterm prelabor rupture of membranes before or around the limit of fetal viability is associated with serious maternal and neonatal complications, including chorioamnionitis, extremely preterm birth, and pulmonary hypoplasia. OBJECTIVE: This s ... Full text Link to item Cite

Darbepoetin, Red Cell Mass, and Neuroprotection in Preterm Infants: A Randomized Clinical Trial.

Journal Article JAMA Pediatr · August 1, 2025 IMPORTANCE: Previous studies suggest that administration of erythropoiesis-stimulating agents darbepoetin or erythropoietin to preterm infants results in fewer transfusions, fewer donor exposures, and improved neurodevelopmental outcome. OBJECTIVE: To dete ... Full text Link to item Cite

Medical treatment of gastroesophageal reflux in the neonatal intensive care unit: current practice.

Journal Article J Perinatol · May 2025 OBJECTIVE: To determine current prescribing practice of acid-suppressive therapy in preterm infants admitted to the neonatal intensive care unit (NICU). STUDY DESIGN: Cohort study of infants 22 to 27 weeks gestation discharged from Pediatrix Medical Group ... Full text Link to item Cite

Whole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants 33 to 35 Weeks' Gestation: A Randomized Clinical Trial.

Journal Article JAMA Pediatr · April 1, 2025 IMPORTANCE: Hypothermia begun less than 6 hours after birth reduces death or disability in infants with encephalopathy due to hypoxia-ischemia at 36 or more weeks' gestation. Trials of hypothermia for infants younger than 36 weeks' gestation are lacking. O ... Full text Link to item Cite

NICHD Magnetic Resonance Brain Imaging Score in Term Infants With Hypoxic-Ischemic Encephalopathy: A Secondary Analysis of a Randomized Clinical Trial.

Journal Article JAMA Pediatr · April 1, 2025 IMPORTANCE: The neonatal brain injury score on magnetic resonance imaging following moderate or severe hypoxic-ischemic encephalopathy developed by the National Institute of Child Health and Human Development Neonatal Research Network has been revised to s ... Full text Link to item Cite

The association of the room air challenge with long-term outcomes in extremely preterm infants.

Journal Article J Perinatol · September 2024 OBJECTIVE: Evaluate the association between results of the room air (RA) challenge and death, respiratory morbidity, and neurodevelopmental impairment (NDI) at 2 years' corrected age. STUDY DESIGN: Cohort study of infants born <27 weeks' gestational age wh ... Full text Link to item Cite

Surgical Necrotizing Enterocolitis and Spontaneous Intestinal Perforation Lead to Severe Growth Failure in Infants.

Journal Article Ann Surg · September 1, 2024 OBJECTIVE: We aimed to determine the incidence of growth failure in infants with necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP) and whether initial laparotomy versus peritoneal drainage (PD) impacted the likelihood of growth fa ... Full text Link to item Cite

Subventricular zone stem cell niche injury is associated with intestinal perforation in preterm infants and predicts future motor impairment.

Journal Article Cell Stem Cell · April 4, 2024 Brain injury is highly associated with preterm birth. Complications of prematurity, including spontaneous or necrotizing enterocolitis (NEC)-associated intestinal perforations, are linked to lifelong neurologic impairment, yet the mechanisms are poorly und ... Full text Link to item Cite

Neurodevelopmental Outcomes of Extremely Preterm Infants Fed Donor Milk or Preterm Infant Formula: A Randomized Clinical Trial.

Journal Article JAMA · February 20, 2024 IMPORTANCE: Maternal milk feeding of extremely preterm infants during the birth hospitalization has been associated with better neurodevelopmental outcomes compared with preterm formula. For infants receiving no or minimal maternal milk, it is unknown whet ... Full text Link to item Cite

Use of term reference infants in assessing the developmental outcome of extremely preterm infants: lessons learned in a multicenter study.

Journal Article J Perinatol · November 2023 OBJECTIVE: Extremely preterm (EP) impairment rates are likely underestimated using the Bayley III norm-based thresholds scores and may be better assessed relative to concurrent healthy term reference (TR) infants born in the same hospital. STUDY DESIGN: Bl ... Full text Link to item Cite

Early-Life Outcomes in Relation to Social Determinants of Health for Children Born Extremely Preterm.

Journal Article J Pediatr · August 2023 OBJECTIVE: To characterize the relationships between social determinants of health (SDOH) and outcomes for children born extremely preterm. STUDY DESIGN: This is a cohort study of infants born at 22-26 weeks of gestation in National Institute of Child Heal ... Full text Link to item Cite

A Pilot Phase I Trial of Allogeneic Umbilical Cord Tissue-Derived Mesenchymal Stromal Cells in Neonates With Hypoxic-Ischemic Encephalopathy.

Journal Article Stem Cells Transl Med · June 15, 2023 Hypoxic ischemic encephalopathy (HIE) in neonates causes increased mortality and long-term morbidity in surviving babies. Hypothermia (HT) has improved outcomes, however, mortality remains high with ~half of surviving babies developing neurological impairm ... Full text Link to item Cite

Quality of life burden on United States infants and caregivers due to lower respiratory tract infection and adjusting for selective testing: Pilot prospective observational study.

Journal Article Health Sci Rep · June 2023 BACKGROUND AND AIMS: Policymakers need data about the burden of respiratory syncytial virus (RSV) lower respiratory tract infections (LRTI) among infants. This study estimates quality of life (QoL) for otherwise healthy term US infants with RSV-LRTI and th ... Full text Link to item Cite

Cortisol awakening response and developmental outcomes at 6-7 years in children born extremely preterm.

Journal Article Pediatr Res · February 2023 BACKGROUND: Extremely preterm (EPT) birth has been related to dysregulation of stress responses and behavioral/learning problems at school age. Early adverse experiences can blunt HPA axis reactivity. We hypothesized that an attenuated cortisol awakening r ... Full text Link to item Cite

The care of the premature infant

Chapter · January 1, 2023 All primary care pediatric providers will encounter patients who were born prematurely and be faced with the unique challenges this patient population holds. Medical advances in the Neonatal Intensive Care Unit (NICU) steadily increase survival rates of pr ... Full text Cite

The Role of Family Members in Providing Support For Malawian Women With Preterm Infants During Infant Hospitalization.

Journal Article Neonatal Netw · November 11, 2022 Purpose: Family support is essential for women with preterm infants during hospitalization. In low-income countries, the additional burden of infant care due to shortages in nursing staff necessitates that family members (guardians) be physically present t ... Full text Link to item Cite

Respiratory Syncytial Virus During the COVID-19 Pandemic Compared to Historic Levels: A Retrospective Cohort Study of a Health System.

Journal Article J Infect Dis · August 15, 2022 BACKGROUND: Surveillance in 2020-2021 showed that seasonal respiratory illnesses were below levels seen during prior seasons, with the exception of interseasonal respiratory syncytial virus (RSV). METHODS: Electronic health record data of infants aged <1 y ... Full text Open Access Link to item Cite

Longitudinal medical needs for periviable NICU survivors.

Journal Article Early Hum Dev · June 2022 OBJECTIVE: To evaluate the technologies required, medications needed, and early intervention services utilized from discharge to 12 months post-discharge for periviable infants (22 0/7 to 24 6/7 weeks gestational age) followed in a comprehensive NICU follo ... Full text Link to item Cite

Experiences of Malawian Mothers During Their Infants' Hospitalization.

Journal Article Adv Neonatal Care · April 1, 2022 BACKGROUND: Hospitalization of a newborn infant is stressful for all mothers. Hospitals in Malawi have limited nursing staff and support, so mothers are the primary care providers for their hospitalized infants. Few studies have explored the experience of ... Full text Link to item Cite

Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia.

Journal Article N Engl J Med · March 24, 2022 BACKGROUND: Bronchopulmonary dysplasia is a prevalent complication after extremely preterm birth. Inflammation with mechanical ventilation may contribute to its development. Whether hydrocortisone treatment after the second postnatal week can improve survi ... Full text Link to item Cite

Survival, Morbidities, and Developmental Outcomes among Low Birth Weight Infants with Congenital Heart Defects.

Journal Article Am J Perinatol · November 2021 OBJECTIVE: Prematurity and low birth weight (LBW) are risk factors for increased morbidity and mortality in infants with congenital heart defects (CHDs). We sought to describe survival, inhospital morbidities, and 2-year neurodevelopmental follow-up in LBW ... Full text Link to item Cite

Growth Rates of Infants Randomized to Continuous Positive Airway Pressure or Intubation After Extremely Preterm Birth.

Journal Article J Pediatr · October 2021 OBJECTIVE: To evaluate the effects of early treatment with continuous positive airway pressure (CPAP) on nutritional intake and in-hospital growth rates of extremely preterm (EPT) infants. STUDY DESIGN: EPT infants (240/7-276/7 weeks of gestation) enrolled ... Full text Link to item Cite

Discharging Medically Complex Infants with Supplemental Nasogastric Tube Feeds: Impact on Neonatal Intensive Care Unit Length of Stay and Prevention of Gastrostomy Tubes.

Journal Article American journal of perinatology · August 2021 ObjectiveThe aim of this study is to evaluate the feasibility, safety, and efficacy of discharge with supplemental nasogastric tube (NGT) feeds in medically complex infants.Study designCohort study of 400 infants enrolled in the Transitio ... Full text Cite

Limitations of Conventional Magnetic Resonance Imaging as a Predictor of Death or Disability Following Neonatal Hypoxic-Ischemic Encephalopathy in the Late Hypothermia Trial.

Journal Article J Pediatr · March 2021 OBJECTIVE: To investigate if magnetic resonance imaging (MRI) is an accurate predictor for death or moderate-severe disability at 18-22 months of age among infants with neonatal encephalopathy in a trial of cooling initiated at 6-24 hours. STUDY DESIGN: Su ... Full text Link to item Cite

Beyond the First Wave: Consequences of COVID-19 on High-Risk Infants and Families.

Journal Article Am J Perinatol · October 2020 The novel coronavirus disease 2019 (COVID-19) pandemic is affecting care for high-risk newborns in ways that will likely be sustained beyond the initial pandemic response. These novel challenges present an urgent imperative to understand how COVID-19 impac ... Full text Link to item Cite

Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia.

Journal Article J Pediatr · April 2020 OBJECTIVE: To characterize behavior of 2-year-old children based on the severity of bronchopulmonary dysplasia (BPD). STUDY DESIGN: We studied children born at 22-26 weeks of gestation and assessed at 22-26 months of corrected age with the Child Behavior C ... Full text Link to item Cite

Timing of postnatal steroids for bronchopulmonary dysplasia: association with pulmonary and neurodevelopmental outcomes.

Journal Article J Perinatol · April 2020 OBJECTIVE: To determine the associations between age at first postnatal corticosteroids (PNS) exposure and risk for severe bronchopulmonary dysplasia (BPD) and neurodevelopmental impairment (NDI). STUDY DESIGN: Cohort study of 951 infants born <27 weeks ge ... Full text Link to item Cite

Impact of Gastrostomy Tube Placement on Short-Term Weight Gain in Hospitalized Premature Infants.

Journal Article JPEN J Parenter Enteral Nutr · February 2020 BACKGROUND: Gastrostomy tube (G-tube) placement is a long-term alternative to oral or nasogastric feeding for premature infants who cannot safely feed orally or need supplemental nutrition for adequate growth. METHODS: We compared daily weight changes for ... Full text Link to item Cite

An Observational Study on Early Dyadic Interactive Behaviors of Mothers With Early-Preterm, Late-Preterm, and Full-Term Infants in Malawi.

Journal Article Adv Neonatal Care · February 2020 BACKGROUND: Mother-infant interactions are necessary for infant growth and development. However, preterm birth is associated with less positive mother-infant interactions than full-term birth. Malawi has the highest preterm birth rate in the world, but stu ... Full text Link to item Cite

Development of parenting self-efficacy in mothers of high-risk infants.

Journal Article Early Hum Dev · February 2020 PURPOSE: The aim of this prospective, longitudinal study was to (1) examine the development of parenting self-efficacy (PSE), (2) explore the influence of contextual factors (e.g., family functioning, family centered care, and infant medical caregiving com ... Full text Link to item Cite

Developmental Outcomes of Extremely Preterm Infants with a Need for Child Protective Services Supervision.

Journal Article J Pediatr · December 2019 OBJECTIVE: To evaluate neurodevelopmental outcomes of preterm infants with need for Child Protective Services (CPS) supervision at hospital discharge compared with those discharged without CPS supervision. STUDY DESIGN: For infants born at <27 weeks of ges ... Full text Link to item Cite

Gastrostomy Tube Feeding in Extremely Low Birthweight Infants: Frequency, Associated Comorbidities, and Long-term Outcomes.

Journal Article J Pediatr · November 2019 OBJECTIVE: To assess the frequency of gastrostomy tube (GT) placement in extremely low birth weight (ELBW) infants, associated comorbidities, and long-term outcomes. STUDY DESIGN: Analysis of ELBW infants from 25 centers enrolled in the National Institute ... Full text Link to item Cite

Inadequate oral feeding as a barrier to discharge in moderately preterm infants.

Journal Article J Perinatol · September 2019 OBJECTIVES: The objectives describe the frequency that inadequate oral feeding (IOF) is the reason why moderately preterm (MPT) infants remain hospitalized and its association with neonatal morbidities. STUDY DESIGN: Prospective study using the NICHD Neona ... Full text Link to item Cite

Adrenal function links to early postnatal growth and blood pressure at age 6 in children born extremely preterm.

Journal Article Pediatr Res · September 2019 BACKGROUND: Low birth weight in term-born individuals correlates with adverse cardiometabolic outcomes; excess glucocorticoid exposure has been linked to these relationships. We hypothesized that cortisol and adrenal androgens would correlate inversely wit ... Full text Link to item Cite

"Choose Physical Therapy" for Neonatal Abstinence Syndrome: Clinical Management for Infants Affected by the Opioid Crisis.

Journal Article Phys Ther · June 1, 2019 In response to the opioid crisis, the American Physical Therapy Association has strongly advocated for physical therapy as a safe alternative to pharmacological pain management through the "#ChoosePT" campaign and the dedication of a PTJ special issue to t ... Full text Link to item Cite

Outcomes of Extremely Preterm Infants With Birth Weight Less Than 400 g.

Journal Article JAMA Pediatr · May 1, 2019 IMPORTANCE: Birth weight (BW) is an important predictor of mortality and morbidity. At extremely early gestational ages (GAs), BW may influence decisions regarding initiation of resuscitation. OBJECTIVE: To characterize outcomes of liveborn infants with a ... Full text Link to item Cite

Care of the Neonatal Intensive Care Unit Graduate after Discharge.

Journal Article Pediatr Clin North Am · April 2019 Premature and critically ill term infants are often discharged from the neonatal intensive care unit (NICU) with ongoing medical problems, including respiratory problems; growth, nutrition and feeding problems; and neurologic injury. At discharge, they may ... Full text Link to item Cite

Neurodevelopmental outcomes among extremely premature infants with linear growth restriction.

Journal Article J Perinatol · February 2019 OBJECTIVE: To compare neurodevelopmental outcomes in linear growth-restricted (LGR) infants born <29 weeks with and without weight gain out of proportion to linear growth. STUDY DESIGN: We compared 2-year neurodevelopmental outcomes between infants with an ... Full text Open Access Link to item Cite

Behavioral Deficits at 18-22 Months of Age Are Associated with Early Cerebellar Injury and Cognitive and Language Performance in Children Born Extremely Preterm.

Journal Article J Pediatr · January 2019 OBJECTIVE: To investigate associations in toddlers born extremely preterm (<28 weeks) between neonatal neuroimaging and 18- to 22-month developmental and behavioral outcomes. STUDY DESIGN: Cohort analysis from the Eunice Kennedy Shriver National Institute ... Full text Link to item Cite

Weaning of Moderately Preterm Infants from the Incubator to the Crib: A Randomized Clinical Trial.

Journal Article J Pediatr · January 2019 OBJECTIVE: To assess whether length of hospital stay is decreased among moderately preterm infants weaned from incubator to crib at a lower vs higher weight. STUDY DESIGN: This trial was conducted in the Eunice Kennedy Shriver National Institute of Child H ... Full text Link to item Cite

Behavioral problems are associated with cognitive and language scores in toddlers born extremely preterm.

Journal Article Early Hum Dev · January 2019 OBJECTIVE: To evaluate the relationship of parent-reported child behaviors on the Child Behavior Checklist (CBCL) to cognition, language, and motor skills on the Bayley Scales of Infant and Toddler Development - III (Bayley-III) in toddlers born extremely ... Full text Link to item Cite

Outcomes of preterm infants treated with hypothermia for hypoxic-ischemic encephalopathy.

Journal Article Early Hum Dev · October 2018 BACKGROUND: Therapeutic hypothermia reduces the risk of death, or moderate to severe neurodevelopmental impairment (NDI) in term infants with hypoxic-ischemic encephalopathy (HIE). Reports of its safety and efficacy in preterm infants are scarce. OBJECTIVE ... Full text Link to item Cite

Extreme Preterm Infant Rates of Overweight and Obesity at School Age in the SUPPORT Neuroimaging and Neurodevelopmental Outcomes Cohort.

Journal Article J Pediatr · September 2018 OBJECTIVE: To identify rates of overweight (body mass index [BMI] ≥85th percentile) and obesity (BMI ≥95th percentile) at 6-7 years of age and associated risk factors among extremely preterm infants born at <28 weeks of gestation. STUDY DESIGN: Anthropomet ... Full text Link to item Cite

Preterm Neuroimaging and School-Age Cognitive Outcomes.

Journal Article Pediatrics · July 2018 BACKGROUND AND OBJECTIVES: Children born extremely preterm are at risk for cognitive difficulties and disability. The relative prognostic value of neonatal brain MRI and cranial ultrasound (CUS) for school-age outcomes remains unclear. Our objectives were ... Full text Link to item Cite

Neurodevelopmental Impairment Among Extremely Preterm Infants in the Neonatal Research Network.

Journal Article Pediatrics · May 2018 OBJECTIVES: Evaluate the spectrum of neurodevelopmental outcome in a contemporary cohort of extremely preterm infants. We hypothesize that the rate of severe neurodevelopmental impairment (NDI) decreases over time. METHODS: Retrospective analysis of neurod ... Full text Link to item Cite

Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age.

Journal Article J Pediatr · April 2018 OBJECTIVE: To determine the outcome of preterm infants whose cystic periventricular leukomalacia "disappeared" on serial screening cranial imaging studies. STUDY DESIGN: Infants ≤26 weeks of gestation born between 2002 and 2012 who had cranial imaging stud ... Full text Link to item Cite

Use of a Midliner Positioning System for Prevention of Dolichocephaly in Preterm Infants.

Journal Article Pediatr Phys Ther · April 2018 PURPOSE: The purpose of this study was to determine effectiveness of a midliner positioning system (MPS, Tortle Midliner) for preventing dolichocephaly. METHODS: This was a nonrandomized, prospective study of 30 premature infants (study cohort, SC) using a ... Full text Link to item Cite

Neurodevelopmental and Behavioral Outcomes in Extremely Premature Neonates With Ventriculomegaly in the Absence of Periventricular-Intraventricular Hemorrhage.

Journal Article JAMA Pediatr · January 1, 2018 IMPORTANCE: Studies of cranial ultrasonography and early childhood outcomes among cohorts of extremely preterm neonates have linked periventricular-intraventricular hemorrhage and cystic periventricular leukomalacia with adverse neurodevelopmental outcomes ... Full text Link to item Cite

Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support.

Journal Article J Pediatr · November 2017 OBJECTIVES: To describe the frequency of postnatal discussions about withdrawal or withholding of life-sustaining therapy (WWLST), ensuing WWLST, and outcomes of infants surviving such discussions. We hypothesized that such survivors have poor outcomes. ST ... Full text Link to item Cite

Timing for the Introduction of Cycled Light for Extremely Preterm Infants: A Randomized Controlled Trial.

Journal Article Res Nurs Health · August 2017 Day-night cycled light improves health outcomes in preterm infants, yet the best time to institute cycled light is unclear. The hypothesis of this study was that extremely preterm infants receiving early cycled light would have better health and developmen ... Full text Link to item Cite

Dolichocephaly in Preterm Infants: Prevalence, Risk Factors, and Early Motor Outcomes.

Journal Article Am J Perinatol · March 2017 Objective The purpose of this study was to determine when dolichocephaly develops in preterm infants, to establish factors that contribute to its development, and to determine its association with adverse motor outcomes. Study Design This study was a retro ... Full text Link to item Cite

Survival and Neurodevelopmental Outcomes among Periviable Infants.

Journal Article N Engl J Med · February 16, 2017 BACKGROUND: Data reported during the past 5 years indicate that rates of survival have increased among infants born at the borderline of viability, but less is known about how increased rates of survival among these infants relate to early childhood neurod ... Full text Link to item Cite

Gastrostomy tube placement in infants with congenital diaphragmatic hernia: Frequency, predictors, and growth outcomes.

Journal Article Early Hum Dev · December 2016 BACKGROUND: Gastrostomy tube (G-tube) placement is a common intervention for newborns with severe feeding difficulties. Infants with congenital diaphragmatic hernia (CDH) are at high risk for feeding problems. Prevalence of G-tube placement and consequent ... Full text Link to item Cite

Growth Outcomes of Preterm Infants Exposed to Different Oxygen Saturation Target Ranges from Birth.

Journal Article J Pediatr · September 2016 OBJECTIVE: To test whether infants randomized to a lower oxygen saturation (peripheral capillary oxygen saturation [SpO2]) target range while on supplemental oxygen from birth will have better growth velocity from birth to 36 weeks postmenstrual age (PMA) ... Full text Link to item Cite

Improved survival and neurodevelopmental outcomes among extremely premature infants born near the limit of viability.

Journal Article Early Hum Dev · April 2016 BACKGROUND: Infants born near the limit of viability are at high risk for death or adverse neurodevelopmental outcomes. It is unclear whether these outcomes have improved over the past 15 years. AIM: To determine if death and neurodevelopmental impairment ... Full text Link to item Cite

Development and validation of the Proxy-Reported Pulmonary Outcomes Scale for premature infants.

Journal Article Am J Perinatol · May 2015 OBJECTIVE: Test the feasibility of using a bedside nurse-reported tool (Proxy-Reported Pulmonary Outcome Scale, PRPOS) for evaluating the severity of bronchopulmonary dysplasia (BPD) by assessing functional, disease-related measures. STUDY DESIGN: Bedside ... Full text Link to item Cite

PaCO2 in surfactant, positive pressure, and oxygenation randomised trial (SUPPORT).

Journal Article Arch Dis Child Fetal Neonatal Ed · March 2015 OBJECTIVE: To determine the association of arterial partial pressure of carbon dioxide PaCO2 with severe intraventricular haemorrhage (sIVH), bronchopulmonary dysplasia (BPD), and neurodevelopmental impairment (NDI) at 18-22 months in premature infants. DE ... Full text Link to item Cite

Beyond the NICU: Comprehensive Care of the High-Risk Infant Comprehensive Care of the High-Risk Infant

Book · October 6, 2014 Improve medical and developmental outcomes in high-risk infants with evidence-based management strategies Beyond the NICU is the first book to deliver practical, evidence-based strategies for healthcare providers caring for the NICU ... ... Cite

Endocrinopathies of the Premature Infant

Chapter · October 6, 2014 Improve medical and developmental outcomes in high-risk infants with evidence-based management strategies Beyond the NICU is the first book to deliver practical, evidence-based strategies for healthcare providers caring for the NICU ... ... Cite

Metoclopramide, H2 blockers, and proton pump inhibitors: pharmacotherapy for gastroesophageal reflux in neonates.

Journal Article Clin Perinatol · March 2012 Pharmacotherapy for gastroesophageal reflux (GER) in neonates, aimed at interfering with this physiologic process and potentially reducing the negative sequelae that providers often attribute to GER, consists primarily of drugs that increase the viscosity ... Full text Link to item Cite

Emotional responses of mothers of late-preterm and term infants.

Journal Article J Obstet Gynecol Neonatal Nurs · 2011 OBJECTIVE: To compare the emotional responses of mothers of late-preterm infants (34 0/7 to 36 6/7 weeks gestation) with those of mothers of full-term infants. DESIGN: A mixed method comparative study. SETTING: A southeastern tertiary academic medical cent ... Full text Link to item Cite

Long-term morbidities associated with vocal cord paralysis after surgical closure of a patent ductus arteriosus in extremely low birth weight infants.

Journal Article J Perinatol · June 2010 OBJECTIVE: Determine associations between left vocal cord paralysis (LVCP) and poor respiratory, feeding and/or developmental outcomes in extremely low birth weight (ELBW) infants following surgical closure of a patent ductus arteriosus (PDA). STUDY DESIGN ... Full text Link to item Cite

Neonatal vocal cord paralysis

Journal Article Neoreviews · December 1, 2009 Neonatal vocal cord paralysis (VCP) remains an important cause of acute and chronic respiratory compromise in infants. Despite a normal cry, infants who have bilateral VCP may present with marked respiratory distress, and emergency tracheostomy is a lifesa ... Full text Cite

Transpyloric tube feeding in very low birthweight infants with suspected gastroesophageal reflux: impact on apnea and bradycardia.

Journal Article J Perinatol · May 2009 Featured Publication OBJECTIVE: Our aim was to assess the safety and efficacy of transpyloric tube feeding as a therapeutic option to reduce apnea and bradycardia in hospitalized very low birthweight (VLBW) infants with clinical signs suggestive of gastroesophageal reflux (GER ... Full text Link to item Cite

Vocal fold paralysis following surgical ductal closure in extremely low birth weight infants: a case series of feeding and respiratory complications.

Journal Article J Perinatol · November 2008 Featured Publication Surgical closure of a patent ductus arteriosus (PDA) continues to be a frequent procedure among extremely preterm infants. Recent evidence indicates surgical closure is associated with worse outcomes than after medical closure. Left vocal fold paralysis is ... Full text Link to item Cite

Use of medications for gastroesophageal reflux at discharge among extremely low birth weight infants.

Journal Article Pediatrics · January 2008 Featured Publication OBJECTIVES: Our goals were (1) to determine the use of medications to treat gastroesophageal reflux in extremely low birth weight infants (birth weight of < 1000 g) at discharge; (2) to identify risk factors associated with the use of medications to treat ... Full text Link to item Cite

Dietary fat for infants with enterostomies.

Journal Article J Pediatr Surg · November 2007 Featured Publication BACKGROUND/PURPOSE: Infants with enterostomies frequently have signs of short bowel syndrome. Our goal was to assess the effect of dietary lipids on ostomy output and weight gain in infants with enterostomies. METHODS: We reviewed the medical records of 10 ... Full text Link to item Cite

Intestinal malrotation in neonates with nonbilious emesis.

Journal Article J Perinatol · June 2006 Intestinal malrotation is a relatively uncommon condition with diverse outcomes. Familiarity with variations in the presentation of malrotation is imperative as early diagnosis and prompt subsequent surgical intervention are essential to optimizing outcome ... Full text Link to item Cite