Journal ArticleEnvironmental research · December 2025
BackgroundAir pollution exposure during pregnancy has been associated with reduced fetal growth and birth weight, but mechanisms mediating this association are not well understood.ObjectivesWe examined whether pregnancy air pollution expo ...
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Journal ArticleAir Quality Atmosphere and Health · December 1, 2025
Air pollution exposure during pregnancy has been associated with reduced fetal size and birth weight, but the sensitive exposure windows for these associations are not well established. We examined the association between gestational air pollution exposure ...
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Journal ArticleJournal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · October 2025
ObjectiveWe previously documented that exposure to a spectrum of elements is associated with autism spectrum disorder (ASD). However, there is a lack of mechanistic understanding as to how elemental mixtures contribute to the ASD development.M ...
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Journal ArticleEnvironment & health (Washington, D.C.) · September 2025
Previous studies documented increased nitrative stress and susceptibility to air pollution among individuals with chronic inflammatory conditions. This study examines the role of anti-inflammatory and cardioprotective nitrated fatty acids (i.e., NO2
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Journal ArticleEnvironmental science & technology letters · September 2025
Quantifying people's exposure to wildfires is essential for assessing related health risks. While hydroxyl metabolites of polycyclic aromatic hydrocarbons (PAHs) are commonly used exposure biomarkers of combustion-originated air pollutants, methylated PAHs ...
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Journal ArticleFASEB J · June 15, 2025
Ozone (O3) is a toxic air pollutant that causes pulmonary inflammation, neutrophil recruitment, and lung injury. Part of the inflammatory response to O3 includes altered expression of formyl peptide receptor 2 (ALX/FPR2), a G protein-coupled receptor expre ...
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Journal ArticleEnviron Res · March 1, 2025
BACKGROUND: Air pollution is a well-documented public health hazard linked to various adverse health outcomes. While studies have shown associations between elevated levels of air pollutants and increased influenza incidence, there is a notable knowledge g ...
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Journal ArticleEnviron Epidemiol · February 2025
BACKGROUND: Sex steroid hormones are critical for maintaining pregnancy and optimal fetal development. Air pollutants are potential endocrine disruptors that may disturb sex steroidogenesis during pregnancy, potentially leading to adverse health outcomes. ...
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Journal ArticleEnvironmental science. Processes & impacts · January 2025
Urinary hydroxylated-polycyclic aromatic hydrocarbons (PAHs), with half-life less than 2 days, are established biomarkers of short-term exposure to PAHs, a ubiquitous constituent of air pollution mixture. In this study, we explore the use of PAHs-hemoglobi ...
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Journal ArticleEnviron Res · November 1, 2024
BACKGROUND: Air pollution exposure during pregnancy has been associated with numerous adverse pregnancy, birth, and child health outcomes. One proposed mechanism underlying these associations is maternal immune activation and dysregulation. We examined ass ...
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Journal ArticleScience bulletin · October 2024
Exposure to polycyclic aromatic hydrocarbons (PAHs) in the Chinese population was among the highest globally and associated with various adverse effects. This study examines the impact of China's two-phase clean air initiatives, namely the Air Pollution Pr ...
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Journal ArticleEnviron Health (Wash) · September 20, 2024
Restricted fetal growth (RFG) is a leading contributor to perinatal mortality and has been associated with gestational exposure to air pollution, such as fine particulate matter (PM2.5), nitrogen dioxide (NO2), and polycyclic aromatic hydrocarbons (PAHs). ...
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Journal ArticleEnviron Sci Technol · September 10, 2024
Epidemiologic evidence has emerged showing an association between exposure to air pollution and increased risks of gestational diabetes mellitus (GDM). This study examines the effect of low-level air pollution exposure on a subclinical biomarker of hypergl ...
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Journal ArticleEnvironmental pollution (Barking, Essex : 1987) · September 2024
Increased systemic oxidative stress, implicated in adverse pregnancy outcomes for both mothers and fetuses, has been associated with gestational exposure to air pollutants such as polycyclic aromatic hydrocarbons (PAHs), fine particulate matter (PM2.5 ...
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Journal ArticleEnvironmental Science and Technology Letters · August 13, 2024
In this study, we developed a novel iodine metabolomic method and identified 42 iodine-containing compounds in urine. Using in vitro experiments, we confirmed that these compounds were degradation metabolites of thyroid hormones (THs) and may be used to un ...
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Journal ArticleJournal of hazardous materials · August 2024
Exposure to ozone (O3) has been associated with cardiovascular outcomes in humans, yet the underlying mechanisms of the adverse effect remain poorly understood. We aimed to investigate the association between O3 exposure and glyceroph ...
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Journal ArticleJ Expo Sci Environ Epidemiol · May 2024
BACKGROUND: Maternal exposure to polycyclic aromatic hydrocarbons (PAHs), ubiquitous constituents of air pollution, has been associated with adverse birth outcomes. Yet it remains unclear whether and how socioeconomic status (SES) affects gestational PAH e ...
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Journal ArticleEnvironmental science & technology letters · March 2024
Climate change has contributed to increased frequency and intensity of wildfire. Studying its acute effects is limited due to unpredictable nature of wildfire occurrence, which necessitates readily deployable techniques to collect biospecimens. To identify ...
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Conference18th Conference of the International Society of Indoor Air Quality and Climate Indoor AIR 2024 Conference Program and Proceedings · January 1, 2024
This study aims to assess the potential benefits of a longer-term indoor HEPA filtration intervention in improving the cardio-metabolic profiles of older adults. We present a profile of sociodemographic, health, and indoor exposure-related lifestyle charac ...
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Journal ArticleAtmospheric environment (Oxford, England : 1994) · November 2023
Random Forest algorithms have extensively been used to estimate ambient air pollutant concentrations. However, the accuracy of model-predicted estimates can suffer from extrapolation problems associated with limited measurement data to train the machine le ...
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Journal ArticleEnvironmental Science and Technology Letters · September 12, 2023
Nitrated aromatic compounds (NACs) belong to a group of ubiquitous environmental contaminants, and lacking exposure markers has restricted the accurate assessment of their exposure and subsequent health effects. Hence, based on gas chromatography and tande ...
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Journal ArticleInternational journal of hygiene and environmental health · August 2023
Diesel exhaust has long been of health concern due to established toxicity including carcinogenicity in humans. However, the precise components of diesel engine emissions that drive carcinogenesis are still unclear. Limited work has suggested that nitrated ...
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Journal ArticleJournal of thoracic disease · August 2023
BackgroundChildhood Asthma Control Test (C-ACT) is a well-validated questionnaire for asthma controls among 4-11 years old children. This study aims to examine if longitudinal C-ACT score changes could also reflect lung pathophysiologic changes.
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Journal ArticleEnvironmental pollution (Barking, Essex : 1987) · June 2023
Mounting evidence suggests that air pollution influences lipid metabolism and dyslipidemia. However, the metabolic mechanisms linking air pollutant exposure and altered lipid metabolism is not established. In year 2014-2018, we conducted a cross-sectional ...
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Journal ArticleJ Pediatr · May 2023
OBJECTIVE: To assess the relationships of prenatal and childhood smoke exposure with specific neurodevelopmental and behavioral problems during early childhood. STUDY DESIGN: A subsample (n = 386) of mother-child dyads from the Newborn Epigenetic Study (NE ...
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Journal ArticleEnvironmental research · September 2022
Exposure to polycyclic aromatic hydrocarbons (PAHs) has been associated with systemic inflammation, yet what mechanisms regulate PAHs' inflammatory effects are less understood. This study evaluated the change of arachidonic acid (ARA) metabolites and infla ...
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Journal ArticleInternational journal of hygiene and environmental health · September 2022
There is a great heterogeneity in smoking prevalence and tobacco control policy across different countries. However, it is unknown whether this heterogeneity could cause increased passive smoking and adverse health effects among international travelers. In ...
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Journal ArticleThe Science of the total environment · June 2022
Conflicted results from previous epidemiological studies call for mechanistic evidence to associate exposure to bisphenol A (BPA) with cardiometabolic diseases. In this natural experiment among healthy travelers from Los Angeles (LA) to Beijing, we collect ...
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Journal ArticleEnvironmental Science and Technology Letters · February 8, 2022
Previous in vitro studies identified carboxylic acids as the major metabolites of methylated polycyclic aromatic hydrocarbons (PAHs). We have previously detected phenanthrene-2-carboxylic acid (2-PHECA) in human urine, but a direct linkage between this bio ...
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Journal ArticleAntioxidants (Basel, Switzerland) · December 2021
Blood biomarkers of oxidative stress and inflammation have been associated with increased risk of hypertension development; yet their application in sub-Saharan Africa has been limited due to the lack of blood collection facilities. In this study, we evalu ...
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Journal ArticleEnvironmental science & technology · August 2021
Despite substantial evidence of marked exposure to and ill-health effects from diesel exhaust (DE) emissions among occupational population (e.g., miners, truck drivers, and taxi drivers), it is less understood to what extent non-occupational population was ...
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Journal ArticleJournal of thoracic disease · June 2021
BackgroundThere are few oxidative biomarkers that can be used in resource-limited settings (e.g., rural Africa) where blood collection facilities are lacking. This study aims to evaluate the potential of malondialdehyde (MDA) in dried blood spots ...
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Journal ArticleEnvironmental science & technology · April 2021
Emerging epidemiological evidence has associated exposure to polycyclic aromatic hydrocarbons (PAHs) with chronic diseases including cardiometabolic diseases and neurodegeneration. However, little information is available about their subacute effects, whic ...
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Journal ArticleEnvironmental science & technology · March 2021
Concerns on nitrated polycyclic aromatic hydrocarbons (nitro-PAHs) in the environment have mainly arisen from their mutagenic and carcinogenic effects. The objective of this study is to investigate whether nitro-PAH exposures are associated with biomarkers ...
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Journal ArticleThe Science of the total environment · March 2021
With the rapid growth of the electronic cigarette (e-cig) market, there is an increasing number of vape shops that exclusively sell e-cigs. The use of e-cigs in the vape shop is a primary source of indoor particles, which might transport to its nearby indo ...
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Journal ArticleEnvironment international · February 2021
Previous studies have found that alkylated polycyclic aromatic hydrocarbons (alkyl-PAHs) were more abundant in petrogenic sources (e.g., crude oil and its refined products) than pyrogenic sources of incomplete combustion. While urinary hydroxylated metabol ...
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Journal ArticleIndoor air · January 2021
Negative ion air purifiers (NIAPs), as a less costly alternative to the HEPA filtration, have been increasingly deployed in China and potentially elsewhere. While reducing indoor concentrations of fine particulate matter (PM2.5 ), NIAPs generate ...
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Journal ArticleEnvironmental pollution (Barking, Essex : 1987) · December 2020
Previous studies have associated the risk of autism spectrum disorder (ASD) with increased exposures to metals and metalloids such as arsenic. In this study, we used an animal-to-human translational strategy to identify key molecular changes that potential ...
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Journal ArticleEnvironment international · December 2020
BackgroundOzone (O3) exposure has been associated with biomarkers of platelet activation and oxidative stress. The metabolism of arachidonic acid (AA) plays an important role in platelet activation and oxidative stress. However, AA meta ...
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Journal ArticleAerosol and Air Quality Research · November 1, 2020
Using an electronic cigarette (e-cig) has been shown to emit a substantial amount of particles and degrade indoor air quality. Here, we tested the effectiveness of different mitigation strategies to reduce indoor particulate pollution due to e-cigs. We sim ...
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Journal ArticleEnvironment international · August 2020
Recent studies suggested a significant downward trend in population's exposure to bisphenol A (BPA) in the United States. However, the temporal trend of BPA exposure remains unclear in China - a populous country with substantial industrial activities but l ...
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Journal ArticleAnnual review of public health · April 2020
With the rapid increase in electronic cigarette (e-cig) users worldwide, secondhand exposure to e-cig aerosols has become a serious public health concern. We summarize the evidence on the effects of e-cigs on indoor air quality, chemical compositions of ma ...
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Conference16th Conference of the International Society of Indoor Air Quality and Climate Creative and Smart Solutions for Better Built Environments Indoor Air 2020 · January 1, 2020Cite
Journal ArticleCirculation · December 2019
BackgroundExposure to air pollution increases cardiovascular morbidity and mortality. Preventing chronic cardiovascular diseases caused by air pollution relies on detecting the early effects of pollutants on the risk of cardiovascular disease deve ...
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Journal ArticleAtmospheric Environment · November 1, 2019
A loading dock is a common functional component of modern commercial and institutional buildings where substantial amount of air pollutants might be emitted by diesel trucks. This study aims to determine whether pollutants in a loading dock could infiltrat ...
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Journal ArticleBeijing Daxue Xuebao Ziran Kexue Ban Acta Scientiarum Naturalium Universitatis Pekinensis · May 20, 2019
A panel study was conducted between Los Angeles and Beijing with 14 healthy young subjects of exchange students from University of California Los Angeles. Urine samples were collected repeatedly and analyzed with a metabolomics approach based on gas chroma ...
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Journal ArticleHuanjing Kexue Xuebao Acta Scientiae Circumstantiae · June 6, 2018
Chemical composition is a key factor on the health effects of ambient fine particulate matter (i.e., PM 2.5 ), but so far evaluation of chemical component exposure to PM 2.5 is restricted by traditional analysis approach in epidemiolo ...
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Journal ArticleAtmospheric Environment · May 1, 2018
Taxi drivers and passengers are exposed to high levels of traffic-related air pollutants, but their exposures to fine (PM2.5) and ultrafine particles (UFPs) and related mitigation strategies are rarely explored. In this study, UFP and PM2.5 ...
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Journal ArticleThe Science of the total environment · January 2018
The human population is both an emitter and receptor of metals. This study aims to clarify how the relationship of metals and metalloids to human populations influences their source characterization and health risk, based on metal concentrations in 298 soi ...
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Journal ArticleEcotoxicology and environmental safety · July 2017
The concentrations of 16 priority polycyclic aromatic hydrocarbons (PAHs) were measured in 128 surface soil samples from Xiangfen County, northern China. The total mass concentration of these PAHs ranged from 52 to 10,524ng/g, with a mean of 723ng/g. Four- ...
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Journal ArticlePloS one · January 2017
Commuters who spend long hours on roads are exposed to high levels of traffic related air pollutants (TRAPs). Despite some well-known multiple adverse effects of TRAPs on human health, limited studies have focused on mitigation strategies to reduce these e ...
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Journal ArticleAtmospheric Environment · January 1, 2017
The authors regret that an error occurs in Equations (2), (3) and (6). The correct versions of the three equations are: [Formula presented] The authors would like to apologise for any inconvenience caused. ...
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Journal ArticleEnvironmental pollution (Barking, Essex : 1987) · December 2016
Atmospheric polycyclic aromatic hydrocarbons (PAHs) and their derivatives are of great concern due to their adverse health effects. However, source identification and apportionment of these compounds, particularly their nitrated and hydroxylated derivative ...
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Journal ArticleACS Omega · November 30, 2016
Fine particulate matter (PM2.5) pollution poses significant health risks worldwide, including metabolic syndrome-related diseases with the characteristic feature of insulin resistance. However, the mechanism and influencing factors of this effec ...
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Journal ArticleThe Science of the total environment · September 2016
Polycyclic aromatic hydrocarbons (PAHs), formed through incomplete combustion process, have adverse health effects. To investigate spatial distribution and sources of PAHs in North China, PAHs with passive sampling in 90 gridded sites during June to Septem ...
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Journal ArticleAtmospheric Environment · August 1, 2016
Nitrated polycyclic aromatic hydrocarbons (NPAHs) are strong environmental mutagens and carcinogens originating from both primary emissions and secondary reactions in the atmosphere. The sources and the toxicity of different NPAH species could vary greatly ...
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Journal ArticleEnvironmental science & technology · April 2016
Air pollution is among the top threats to human health in China. As air toxicants, polycyclic aromatic hydrocarbons (PAHs) could bring significant risks to population; however, the exposure to PAHs in China and its health impact are not fully understood. I ...
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Journal ArticleEnvironmental science and pollution research international · September 2015
Eighty-seven soil samples collected from North China were analyzed for decabromodiphenyl ethane (DBDPE). The concentrations of DBDPE ranged from undetectable to 1612 ng/g, with the highest concentration present in Shandong. Additionally, the mean concentra ...
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Journal ArticleJournal of Geophysical Research · January 1, 2015
Fine particulate matter (PM2.5) is a significant health issue in Chinese megacities. However, little information is available regarding the PM2.5-bound toxic organics, especially their sources, atmospheric transformations, and health implication ...
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Journal ArticleEnvironmental pollution (Barking, Essex : 1987) · January 2015
The occurrence of polycyclic aromatic hydrocarbons (PAHs) and nitrated derivatives (NPAHs), as well as their transformation may have significant health impacts on humans. To investigate the level, spatial distribution and the transformation process of PAHs ...
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Journal ArticleArchives of environmental contamination and toxicology · May 2014
Polybrominated diphenyl ethers (PBDEs) were measured in 87 soil samples collected from North China. Eleven PBDE congeners (BDE28, 47, 49, 66, 99, 100, 119, 183, 196, 203, and 209) were identified with a high frequency of detection (84-100 %) in soil sample ...
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Journal ArticleEnvironmental science & technology · November 2013
Brominated flame retardants (BFRs) are important persistent organic pollutants. Analysis of BFRs in atmospheric samples in a previous study led us to suspect the presence of unidentified organic bromides, other than polybrominated diphenyl ethers (PBDEs), ...
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Journal ArticleEnvironmental pollution (Barking, Essex : 1987) · September 2013
Polychlorinated naphthalenes (PCNs) belong to a group of dioxin-like pollutants; however little information is available on PCNs in North China. In this study, gridded field observations by passive air sampling at 90 sites were undertaken to determine the ...
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Journal ArticleEnvironmental science & technology · August 2013
Brominated flame retardants (BFRs) such as polybrominated diphenyl ethers (PBDEs) are important pollutants, yet few data on ambient BFRs levels have been available for North China, one of the most developed regions of the country. In this study, we investi ...
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Journal ArticleEnvironmental science & technology · July 2013
Although levels of poly- and perfluoroalkyl substances (PFASs) in human maternal and neonatal blood have been widely reported in the literature, relationship of maternal-fetal transmission of PFASs with carbon chain length is presently not well understood. ...
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Journal ArticleJournal of agricultural and food chemistry · October 2011
Despite the growing public interest in perfluorinated compounds (PFCs), very few studies have reported the sources and pathways of human exposure to these compounds in China. In this study, concentrations of 10 PFCs were measured in human blood, water (tap ...
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