Scholars@Duke
Rajan Tilak Gupta

Rajan Tilak Gupta

Professor of Radiology
Radiology, Abdominal Imaging
rajan.gupta@duke.edu
Department of Radiology, BOX_3808 Med Ctr, Durham, NC 27710

Selected Publications

Improving Prostate MRI: Lessons Learned from the American College of Radiology's Prostate MR Image Quality Improvement Collaborative.

Journal Article Radiographics · January 2026 MRI is an essential tool in diagnosis and management of prostate cancer. However, image quality and interpretation variability continue to hinder its broader adoption in clinical practice. To address the challenge of inconsistent image quality, the America ... Full text Link to item Cite

Prognostic significance of magnetic resonance imaging-detected extraprostatic extension in localized prostate cancer.

Journal Article Cancer · December 1, 2025 BACKGROUND: Magnetic resonance imaging (MRI) findings are not currently included in prostate cancer (PC) staging. Yet the presence of MRI-detected extraprostatic extension (EPE) may indicate higher risk disease. The purpose of this study was to assess the ... Full text Link to item Cite

Detection of clinically significant prostate cancer using targeted MRI-informed microultrasound biopsy.

Journal Article Eur Radiol · November 22, 2025 OBJECTIVES: This study compares the rate of detection of clinically significant prostate cancer (csPCa) using multiparametric MRI (mpMRI)-informed microultrasound-guided (microUS) biopsy to historical published data using mpMRI-ultrasound (mpMRI-US) fusion ... Full text Link to item Cite

External validation of inter-reader reliability of the Prostate Imaging after Focal Ablation (PI-FAB) scoring system following focal cryoablation and focal high-intensity focused ultrasound.

Journal Article Eur Radiol · November 2025 OBJECTIVES: The efficacy of focal therapy (FT) has improved with the use of multiparametric MRI (mpMRI) for lesion identification, though standardized mpMRI reporting post-FT is lacking. The Prostate Imaging after Focal Ablation (PI-FAB) scoring system was ... Full text Link to item Cite

Transcriptomic predictors of prostate cancer recurrence following focal cryotherapy: a pooled analysis of phase II trial and prospective cohort data.

Journal Article J Natl Cancer Cent · October 2025 OBJECTIVE: Focal therapy (FT) is a potential treatment option for limited-volume clinically-significant prostate cancer (csPCa). However, despite rigorous selection, approximately 20% of patients experience early failure. We investigated the association of ... Full text Link to item Cite

ACR Appropriateness Criteria® Renal Transplant Dysfunction: 2024 Update.

Journal Article J Am Coll Radiol · May 2025 Renal transplantation remains the treatment of choice in patients with end-stage renal disease as the 5-year survival rates for the graft in renal transplant patients range from 72% to 99%. Despite improvements in graft survival related to increased effica ... Full text Link to item Cite

Employing a Quality Improvement Program to Optimize mpMRI-Directed Fusion Biopsy

Chapter · January 1, 2025 From the first published study in 1982, over 40 years of remarkable efforts have made prostate MRI a pivotal clinical tool in prostate cancer (PCa) management. Today, the role of multiparametric MRI (mpMRI) in focal therapy practice starts from the primary ... Full text Cite

PI-QUAL version 2: an update of a standardised scoring system for the assessment of image quality of prostate MRI.

Journal Article Eur Radiol · November 2024 Multiparametric MRI is the optimal primary investigation when prostate cancer is suspected, and its ability to rule in and rule out clinically significant disease relies on high-quality anatomical and functional images. Avenues for achieving consistent hig ... Full text Link to item Cite

Image-guided multiparametric magnetic resonance imaging-transrectal ultrasound fusion biopsy augmented with a sextant versus an extended template random biopsy: Comparison of cancer detection rates, complication and functional outcomes.

Journal Article Prostate · September 2024 PURPOSE: To compare the efficacy of a novel fusion template "reduced six-core systemic template and multiparametric magnetic resonance imaging/transrectal ultrasound (mpMRI/TRUS) fusion targeted biopsy" (TBx+6c), with mpMRI/TRUS fusion-targeted biopsy and ... Full text Link to item Cite

Improving Prostate MR Image Quality in Practice-Initial Results From the ACR Prostate MR Image Quality Improvement Collaborative.

Journal Article J Am Coll Radiol · September 2024 OBJECTIVE: Variability in prostate MRI quality is an increasingly recognized problem that negatively affects patient care. This report aims to describe the results and key learnings of the first cohort of the ACR Learning Network Prostate MR Image Quality ... Full text Link to item Cite

Radiologic Evaluation of the Distal End Radius Indices in Indian Paediatric Population

Journal Article Indian Journal of Orthopaedics · September 2024 Full text Cite

A rare case of extensive neurogenic heterotopic ossification: a case report

Journal Article BMC Musculoskeletal Disorders · April 23, 2024 AbstractIntroductionNeurogenic Heterotopic ossification (NHO) is a potential sequalae and a detrimental complication following ... Full text Cite

Interpretation of Prostate Magnetic Resonance Imaging Using Prostate Imaging and Data Reporting System Version 2.1: A Primer.

Journal Article Radiol Clin North Am · January 2024 Prostate magnetic resonance imaging (MRI) is increasingly being used to diagnose and stage prostate cancer. The Prostate Imaging and Data Reporting System (PI-RADS) version 2.1 is a consensus-based reporting system that provides a standardized and reproduc ... Full text Link to item Cite

Impact of pre-treatment MRI capsular involvement and extraprostatic extension on metastasis free and overall survival in localized prostate cancer

Conference Journal of Clinical Oncology · January 1, 2024 Background: Multiparametric magnetic resonance imaging (mpMRI) is not currently included in prostate cancer (PC) staging. The purpose of this study was to test the association between mpMRI detected prostate capsule involvement and extraprostatic extension ... Full text Cite

Association of multiparametric magnetic resonance imaging findings with oncologic outcomes in non-palpable localized prostate cancer.

Conference Journal of Clinical Oncology · January 1, 2024 Background: Multiparametric magnetic resonance imaging (mpMRI) is becoming increasingly integrated into the evaluation and medical decision making for localized prostate cancer. However, mpMRI findings have not been correlated with prostate cancer outcomes ... Full text Cite

Prognostic significance of muscle fasciculations in critically Ill COVID-19 patients under mechanical ventilation

Journal Article Frontiers in Anesthesiology · January 1, 2024 Introduction: The COVID-19 pandemic brought unprecedented challenges to healthcare systems worldwide, particularly the often challenging physical recovery from critical illness. Among the myriad complications faced by these patients, ICU-acquired weakness ... Full text Cite

A novel ultrasound approach in assessing IMAT in critically ill patients

Journal Article Frontiers in Anesthesiology · January 1, 2024 Background: Muscle wasting is a common finding in critically ill patients associated with increased days of mechanical ventilation in the ICU. Muscle wasting and associated morphological changes are hallmarks of ICU-acquired weakness. Muscle wasting can be ... Full text Cite

Evaluation of Recurrent Disease after Radiation Therapy for Patients Considering Local Salvage Therapy: Past vs. Contemporary Management.

Journal Article Cancers (Basel) · December 18, 2023 Recurrent prostate cancer after primary treatment with radiation therapy is a common problem. Patients with localized recurrence may benefit from salvage therapy, but careful patient selection is crucial because not all patients will benefit from local sal ... Full text Link to item Cite

Relationship Between Pretreatment Body Composition and Clinical Outcomes in Patients With Metastatic Renal Cell Carcinoma Receiving First-Line Ipilimumab Plus Nivolumab.

Journal Article Clin Genitourin Cancer · December 2023 INTRODUCTION: Biomarkers are needed to identify patients with metastatic renal cell carcinoma (mRCC) most likely to benefit from immune checkpoint inhibitors. We examined associations between radiographically assessed body composition (BC) variables and bo ... Full text Link to item Cite

Surveillance one year post focal cryotherapy for clinically significant prostate cancer using mpMRI and PIRADS v2.1: An initial experience from a prospective phase II mandatory biopsy study.

Journal Article Eur J Radiol Open · December 2023 OBJECTIVES: Multiparametric magnetic resonance imaging (mpMRI) surveillance post focal cryotherapy (FT) of prostate cancer is challenging as post treatment artefacts alter mpMRI findings. In this initial experience, we assessed diagnostic performance of mp ... Full text Link to item Cite

ACR Appropriateness Criteria® Acute Onset Flank Pain-Suspicion of Stone Disease (Urolithiasis).

Journal Article J Am Coll Radiol · November 2023 Noncontrast CT (NCCT) is the imaging study of choice for initial evaluation of patients with acute onset of flank pain and suspicion of stone disease without known prior stone disease. NCCT can reliably characterize the location and size of an offending ur ... Full text Link to item Cite

Optimization of non-endorectal prostate MR image quality using PI-QUAL: A multidisciplinary team approach.

Journal Article Eur J Radiol · September 2023 PURPOSE: To evaluate the utility of the PI-QUAL score in assessing protocol changes aimed to improve image quality from a non-endorectal coil prostate MR imaging protocol during a 9-month quality improvement (QI) project and to quantify the inter-reader ag ... Full text Link to item Cite

A Faster Prostate MRI: Comparing a Novel Denoised, Single-Average T2 Sequence to the Conventional Multiaverage T2 Sequence Regarding Lesion Detection and PI-RADS Score Assessment.

Journal Article J Magn Reson Imaging · August 2023 BACKGROUND: The T2 w sequence is a standard component of a prostate MRI examination; however, it is time-consuming, requiring multiple signal averages to achieve acceptable image quality. PURPOSE/HYPOTHESIS: To determine whether a denoised, single-average ... Full text Link to item Cite

American College of Radiology initiatives on prostate magnetic resonance imaging quality.

Journal Article Eur J Radiol · August 2023 Magnetic resonance imaging (MRI) has become integral to diagnosing and managing patients with suspected or confirmed prostate cancer. However, the benefits of utilizing MRI can be hindered by quality issues during imaging acquisition, interpretation, and r ... Full text Link to item Cite

Reconciling discordance between PI-RADS 4 lesions and targeted biopsy: Early experience of a multidisciplinary quality improvement protocol with PI-RADS 4 subcategorization.

Journal Article Eur J Radiol · August 2023 PURPOSE: PI-RADS 4 lesions are considered to have a "high" likelihood of clinically-significant prostate cancer (csPCa). However, patients undergoing targeted biopsy have a range of histologic findings. Understanding discordant cases is critical to improve ... Full text Link to item Cite

Initial Longitudinal Outcomes of Risk-Stratified Men in Their Forties Screened for Prostate Cancer Following Implementation of a Baseline Prostate-Specific Antigen.

Journal Article World J Mens Health · July 2023 PURPOSE: Prostate cancer (PCa) screening can lead to potential over-diagnosis/over-treatment of indolent cancers. There is a need to optimize practices to better risk-stratify patients. We examined initial longitudinal outcomes of mid-life men with an elev ... Full text Link to item Cite

Utility of a Rule-Based Algorithm in the Assessment of Standardized Reporting in PI-RADS.

Journal Article Acad Radiol · June 2023 RATIONALE AND OBJECTIVES: Adoption of the Prostate Imaging Reporting & Data System (PI-RADS) has been shown to increase detection of clinically significant prostate cancer on prostate mpMRI. We propose that a rule-based algorithm based on Regular Expressio ... Full text Link to item Cite

Patient-reported functional outcomes and oncological control after primary focal cryotherapy for clinically significant prostate cancer: A Phase II mandatory biopsy-monitored study.

Journal Article Prostate · June 2023 INTRODUCTION: We report herein the impact of focal therapy (FT) on multi-domain functional outcomes in a Phase II prospective clinical trial (NCT04138914) in focal cryotherapy for clinically significant prostate cancer (csPCa). METHODS: The primary outcome ... Full text Link to item Cite

ACR Appropriateness Criteria® Staging of Renal Cell Carcinoma: 2022 Update.

Journal Article J Am Coll Radiol · May 2023 Renal cell carcinoma is a complex group of highly heterogenous renal tumors demonstrating variable biological behavior. Pretreatment imaging of renal cell carcinoma involves accurate assessment of the primary tumor, presence of nodal, and distant metastase ... Full text Link to item Cite

Prostate MRI Qualification: AJR Expert Panel Narrative Review.

Journal Article AJR Am J Roentgenol · November 2022 Prostate MRI is now established as a first-line investigation for individuals presenting with suspected localized or locally advanced prostate cancer. Successful delivery of the MRI-directed pathway for prostate cancer diagnosis relies on high-quality imag ... Full text Link to item Cite

ACR Appropriateness Criteria® Acute Pyelonephritis: 2022 Update.

Journal Article J Am Coll Radiol · November 2022 Acute pyelonephritis (APN) is a severe urinary tract infection (UTI) that has the potential to cause sepsis, shock, and death. In the majority of patients, uncomplicated APN is diagnosed clinically and is responsive to treatment with appropriate antibiotic ... Full text Link to item Cite

Molecular biomarkers in the context of focal therapy for prostate cancer: recommendations of a Delphi Consensus from the Focal Therapy Society.

Journal Article Minerva Urol Nephrol · October 2022 BACKGROUND: Focal therapy (FT) for prostate cancer (PCa) is promising. However, long-term oncological results are awaited and there is no consensus on follow-up strategies. Molecular biomarkers (MB) may be useful in selecting, treating and following up men ... Full text Link to item Cite

Reconciling Discordance Between Prostate Biopsy Histology and Magnetic Resonance Imaging Suspicion - Implementation of a Quality Improvement Protocol of Imaging Re-review and Reverse-fusion Target Analysis.

Journal Article Eur Urol Oncol · October 2022 There is uncertainty with how to proceed when targeted prostate biopsy of suspicious multiparametric magnetic resonance imaging (mpMRI) lesions return without clinically significant prostate cancer (csPCa). While possible, there are error sources that coul ... Full text Link to item Cite

Evaluation of tumor microenvironment and biomarkers of immune checkpoint inhibitor response in metastatic renal cell carcinoma.

Journal Article J Immunother Cancer · October 2022 BACKGROUND: Immunotherapy combinations including ipilimumab and nivolumab are now the standard of care for untreated metastatic renal cell carcinoma (mRCC). Biomarkers of response are lacking to predict patients who will have a favorable or unfavorable res ... Full text Open Access Link to item Cite

Automated versus manual analysis of body composition measures on computed tomography in patients with bladder cancer.

Journal Article Eur J Radiol · September 2022 PURPOSE: Manual measurement of body composition on computed tomography (CT) is time-consuming, limiting its clinical use. We validate a software program, Automatic Body composition Analyzer using Computed tomography image Segmentation (ABACS), for the auto ... Full text Link to item Cite

Structured approach to resolving discordance between PI-RADS v2.1 score and targeted prostate biopsy results: an opportunity for quality improvement.

Journal Article Abdom Radiol (NY) · August 2022 BACKGROUND: Prostate multiparametric magnetic resonance imaging (mpMRI) can identify lesions within the prostate with characteristics identified in Prostate Imaging Reporting and Data System (PI-RADS) v2.1 associated with clinically significant prostate ca ... Full text Link to item Cite

ACR Appropriateness Criteria® Post-Treatment Follow-up and Active Surveillance of Clinically Localized Renal Cell Carcinoma: 2021 Update.

Journal Article J Am Coll Radiol · May 2022 Renal cell carcinoma (RCC) accounts for most malignant renal tumors and is considered the most lethal of all urologic cancers. For follow-up of patients with treated or untreated RCC and those with neoplasms suspected to represent RCC, radiologic imaging i ... Full text Link to item Cite

Successful Diagnosis and Treatment of Occult Prostate Cancer Despite Multiple Negative Prostate Biopsies and Negative Prostate MRIs.

Journal Article Oncology (Williston Park) · March 8, 2022 Prostate-specific antigen (PSA) values above 100 ng/mL often suggest metastatic prostate cancer. We present the case of a patient with a PSA of 110 ng/mL, 4 negative prostate biopsies, and 4 negative prostate MRIs. After his fifth MRI revealed a PI-RADS 5 ... Full text Open Access Link to item Cite

A randomized controlled trial comparing changes in fitness with or without supervised exercise in patients initiated on enzalutamide and androgen deprivation therapy for non-metastatic castration-sensitive prostate cancer (EXTEND).

Journal Article Prostate Cancer Prostatic Dis · March 2022 BACKGROUND: Androgen deprivation therapy (ADT) and androgen receptor signaling inhibitors (ARSI) are associated with deleterious physical effects, which exercise may mitigate; however, exercise has never been studied in patients initiating treatment with A ... Full text Link to item Cite

The SCARD Fellowship Policy and the Abdominal Imaging Fellowship: A Follow-up Survey After the First Year.

Journal Article Acad Radiol · February 2022 RATIONALE AND OBJECTIVES: To assess resident and fellowship program director (PD) perceptions of the abdominal radiology fellowship application process following the first cycle in which an embargo on interviews until December 1, 2019 was set according to ... Full text Link to item Cite

Pericardial Adipose Tissue Volume and Left Ventricular Assist Device-Associated Outcomes.

Journal Article J Card Fail · January 2022 BACKGROUND: Pericardial adipose tissue (PAT) is associated with adverse cardiovascular outcomes in those with and without established heart failure (HF). However, it is not known whether PAT is associated with adverse outcomes in patients with end-stage HF ... Full text Link to item Cite

Past, present, and future of abdominal radiology fellowship recruitment.

Journal Article Abdom Radiol (NY) · December 2021 The authors provide a commentary on the current status of the Abdominal Radiology Fellowship recruitment process, which is not presently governed by a formal Match. Abdominal Radiology is the largest radiology subspecialty fellowship that remains outside o ... Full text Link to item Cite

Utilization of focal therapy for patients discontinuing active surveillance of prostate cancer: Recommendations of an international Delphi consensus.

Journal Article Urol Oncol · November 2021 BACKGROUND: With the advancement of imaging technology, focal therapy (FT) has been gaining acceptance for the treatment of select patients with localized prostate cancer (CaP). We aim to provide details of a formal physician consensus on the utilization o ... Full text Link to item Cite

ACR Appropriateness Criteria® Adrenal Mass Evaluation: 2021 Update.

Journal Article J Am Coll Radiol · November 2021 The appropriate evaluation of adrenal masses is strongly dependent on the clinical circumstances in which it is discovered. Adrenal incidentalomas are masses that are discovered on imaging studies that have been obtained for purposes other than adrenal dis ... Full text Link to item Cite

Artificial Intelligence-assisted Prostate Cancer Diagnosis: Radiologic-Pathologic Correlation.

Journal Article Radiographics · October 2021 The classic prostate cancer (PCa) diagnostic pathway that is based on prostate-specific antigen (PSA) levels and the findings of digital rectal examination followed by systematic biopsy has shown multiple limitations. The use of multiparametric MRI (mpMRI) ... Full text Link to item Cite

Intravascular Ultrasound-Guided Transvenous Biopsy of Abdominal and Pelvic Targets Difficult to Access by Percutaneous Needle Biopsy: Technique and Initial Clinical Experience.

Journal Article J Vasc Interv Radiol · September 2021 PURPOSE: To report initial clinical experience with intravascular ultrasound (US)-guided transvenous biopsy (TVB) for perivascular target lesions in the abdomen and pelvis using side-viewing phased-array intracardiac echocardiography catheters. MATERIALS A ... Full text Link to item Cite

Can procedure time for paracentesis be optimized based on bottle selection?

Journal Article Abdom Radiol (NY) · August 2021 PURPOSE: The purpose of our study was to assess if plastic containers could decrease the overall procedure time for paracentesis relative to more commonly used glass containers. METHODS: In this IRB exempt study, initial pilot data comparing filling time o ... Full text Link to item Cite

PROSPER: Phase III RandOmized Study Comparing PERioperative nivolumab versus observation in patients with renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN EA8143).

Conference Journal of Clinical Oncology · May 20, 2021 TPS4596 Background: There is no standard adjuvant systemic therapy that increases overall survival (OS) over surgery alone for non-metastatic RCC. Anti-PD-1 nivolumab (nivo) improves OS in metastatic RCC and is well tolerated. In ... Full text Cite

ACR Appropriateness Criteria® Renal Failure.

Journal Article J Am Coll Radiol · May 2021 Renal failure can be divided into acute kidney injury and chronic kidney disease. Both are common and result in increased patient morbidity and mortality. The etiology is multifactorial and differentiation of acute kidney injury from chronic kidney disease ... Full text Link to item Cite

Diet and Exercise Are not Associated with Skeletal Muscle Mass and Sarcopenia in Patients with Bladder Cancer.

Journal Article Eur Urol Oncol · April 2021 BACKGROUND: There is limited understanding about why sarcopenia is happening in bladder cancer, and which modifiable and nonmodifiable patient-level factors affect its occurrence. OBJECTIVE: The objective is to determine the extent to which nonmodifiable r ... Full text Open Access Link to item Cite

Combination antiangiogenic tyrosine kinase inhibition and anti-PD1 immunotherapy in metastatic renal cell carcinoma: A retrospective analysis of safety, tolerance, and clinical outcomes.

Journal Article Cancer Med · April 2021 INTRODUCTION: Two separate antiangiogenic tyrosine kinase inhibitors (TKIs) and immunotherapy (IO) combinations are FDA-approved as front-line treatment for metastatic renal cell carcinoma (mRCC). Little is known about off-protocol and post-front-line expe ... Full text Link to item Cite

How frequently does hepatocellular carcinoma develop in at-risk patients with a negative liver MRI examination with intravenous Gadobenate dimeglumine?

Journal Article Abdom Radiol (NY) · March 2021 OBJECTIVE: To determine the rate of development of clinically significant liver nodules (LR-4, LR-5, LR-M) after a negative MRI in an HCC screening population. METHODS: This retrospective study included patients at risk of developing HCC requiring imaging ... Full text Link to item Cite

LRP1B mutations are associated with favorable outcomes to immune checkpoint inhibitors across multiple cancer types.

Journal Article J Immunother Cancer · March 2021 BACKGROUND: Low-density lipoprotein receptor-related protein 1b (encoded by LRP1B) is a putative tumor suppressor, and preliminary evidence suggests LRP1B-mutated cancers may have improved outcomes with immune checkpoint inhibitors (ICI). METHODS: We condu ... Full text Open Access Link to item Cite

Implementation and Impact of a Risk-Stratified Prostate Cancer Screening Algorithm as a Clinical Decision Support Tool in a Primary Care Network.

Conference J Gen Intern Med · January 2021 BACKGROUND: Implementation methods of risk-stratified cancer screening guidance throughout a health care system remains understudied. OBJECTIVE: Conduct a preliminary analysis of the implementation of a risk-stratified prostate cancer screening algorithm i ... Full text Link to item Cite

PD-L1 Assay Concordance in Metastatic Renal Cell Carcinoma and Metastatic Urothelial Carcinoma.

Journal Article Clin Genitourin Cancer · December 2020 BACKGROUND: Immune checkpoint inhibitors are now standard of care for many patients with metastatic renal cell carcinoma (mRCC) and metastatic urothelial carcinoma (mUC). Given real-world limitations in programmed death-ligand 1 (PD-L1) testing, concordanc ... Full text Link to item Cite

ACR Appropriateness Criteria® Indeterminate Renal Mass.

Journal Article J Am Coll Radiol · November 2020 Renal masses are increasingly detected in asymptomatic individuals as incidental findings. CT and MRI with intravenous contrast and a dedicated multiphase protocol are the mainstays of evaluation for indeterminate renal masses. A single-phase postcontrast ... Full text Link to item Cite

Esophageal Function Tests are Not Associated with Barium Swallow Findings in Advanced Lung Disease.

Journal Article Dysphagia · October 2020 Gastroesophageal reflux disease and esophageal dysmotility are common in patients with advanced lung disease (ALD) and are associated with worse outcomes. Assessing esophageal function in these patients is relevant for determining pulmonary transplant elig ... Full text Link to item Cite

Correction to: Esophageal Function Tests are Not Associated with Barium Swallow Findings in Advanced Lung Disease.

Journal Article Dysphagia · October 2020 The original version of this article unfortunately contained a mistake. The shared first authorship information was missing in the published article. It has been given below. The first authorship is shared between Dr. Shai Posner and Kurren Mehta. ... Full text Link to item Cite

Assessments of frailty in bladder cancer.

Journal Article Urol Oncol · September 2020 BACKGROUND AND AIMS: The incidence of frailty is increasing as the population ages, which has important clinical implications given the associations between frailty and poor outcomes in the bladder cancer population. Due to a multi-organ system decline and ... Full text Open Access Link to item Cite

PI-RADS: Past, present, and future.

Journal Article J Magn Reson Imaging · July 2020 Prostate cancer (PCa) is extremely prevalent and is the most common noncutaneous malignancy and second-most common cause of cancer death in men. In the last decade, there has been dramatic growth in the use of multiparametric magnetic resonance imaging (mp ... Full text Link to item Cite

Post-treatment prostate MRI.

Journal Article Abdom Radiol (NY) · July 2020 Accurate early detection of recurrent prostate cancer after surgical or nonsurgical treatment is increasingly relevant in the era of evolving options for salvage therapy. The importance of differentiating between local tumor recurrence, distant metastatic ... Full text Link to item Cite

MRI/TRUS fusion vs. systematic biopsy: intra-patient comparison of diagnostic accuracy for prostate cancer using PI-RADS v2.

Journal Article Abdom Radiol (NY) · July 2020 OBJECTIVE: To evaluate the efficacy of multiparametric magnetic resonance/transrectal ultrasound fusion (MRI/TRUS fusion) biopsy versus systematic biopsy and its association with PI-RADS v2 categories in patients with suspected prostate cancer. MATERIALS A ... Full text Link to item Cite

Variability of the Positive Predictive Value of PI-RADS for Prostate MRI across 26 Centers: Experience of the Society of Abdominal Radiology Prostate Cancer Disease-focused Panel.

Journal Article Radiology · July 2020 Background Prostate MRI is used widely in clinical care for guiding tissue sampling, active surveillance, and staging. The Prostate Imaging Reporting and Data System (PI-RADS) helps provide a standardized probabilistic approach for identifying clinically s ... Full text Link to item Cite

Proliferative potential and response to nivolumab in clear cell renal cell carcinoma patients.

Journal Article Oncoimmunology · June 10, 2020 BACKGROUND: Biomarkers predicting immunotherapy response in metastatic renal cell cancer (mRCC) are lacking. PD-L1 immunohistochemistry is a complementary diagnostic for immune checkpoint inhibitors (ICIs) in mRCC, but has shown minimal clinical utility an ... Full text Link to item Cite

Prospects of a Fellowship Match for Abdominal Imaging: A National Survey by the Society of Abdominal Radiology.

Journal Article J Am Coll Radiol · June 2020 PURPOSE: After the Society of Chairs of Academic Radiology Departments timeline and guidelines were released for the 2021 through 2022 fellowship application cycle, the Society of Abdominal Radiology conducted a survey of residents, fellows, and abdominal ... Full text Link to item Cite

ACR Appropriateness Criteria® Hematuria.

Journal Article Journal of the American College of Radiology : JACR · May 2020 Hematuria is a common reason for patients to be referred for imaging of the urinary tract. All patients diagnosed with hematuria should undergo a thorough history and physical examination, urinalysis, and serologic testing prior to any initial imaging. Ult ... Full text Cite

Characterization of tumor mutation burden, PD-L1 and DNA repair genes to assess relationship to immune checkpoint inhibitors response in metastatic renal cell carcinoma.

Journal Article J Immunother Cancer · March 2020 BACKGROUND: Immune checkpoint inhibitors (ICIs) have expanded treatment options for metastatic renal cell carcinoma (mRCC); however, there are limited predictive biomarkers for response to ICIs in this indication, with programmed death-ligand 1 (PD-L1) sta ... Full text Link to item Cite

Anterior gland focal cryoablation: proof-of-concept primary prostate cancer treatment in select men with localized anterior cancers detected by multi-parametric magnetic resonance imaging.

Journal Article BMC Urol · December 5, 2019 BACKGROUND: Due to their location away from the nerve bundles, anterior prostate cancers (APC) represent a rational target for image-guided cryoablation. This report describes the feasibility and short-term outcomes of anterior focal cryosurgery. METHODS: ... Full text Link to item Cite

Clinical utility of FoundationOne tissue molecular profiling in men with metastatic prostate cancer.

Journal Article Urol Oncol · November 2019 PURPOSE: Targeted inhibitors and immunotherapy have entered the treatment landscape of metastatic prostate cancer. Genomic testing may uncover which patients benefit most from these therapies. We report the clinical utility and benefits of FoundationOne te ... Full text Link to item Cite

ACR Appropriateness Criteria® Post-Treatment Follow-up and Active Surveillance of Clinically Localized Renal Cell Cancer.

Journal Article J Am Coll Radiol · November 2019 Renal cell carcinoma (RCC) accounts for most malignant renal tumors and is considered the most lethal of all urologic cancers. For follow-up of patients with treated or untreated RCC and those with neoplasms suspected to represent RCC, radiologic imaging i ... Full text Link to item Cite

LI-RADS: Diagnostic Performance of Hepatobiliary Phase Hypointensity and Major Imaging Features of LR-3 and LR-4 Lesions Measuring 10-19 mm With Arterial Phase Hyperenhancement.

Journal Article AJR Am J Roentgenol · August 2019 OBJECTIVE. The purpose of this study was to determine the diagnostic performance of hepatobiliary phase hypointensity and Liver Imaging Reporting and Data System (LI-RADS) major imaging features in the diagnosis of hepatocellular carcinoma (HCC) in hepatic ... Full text Link to item Cite

Pembrolizumab in men with heavily treated metastatic castrate-resistant prostate cancer.

Journal Article Cancer Med · August 2019 BACKGROUND: Pembrolizumab is approved for patients with metastatic, microsatellite instability (MSI)-high or mismatch repair-deficient (dMMR) solid tumors. However, very few men with prostate cancer were included in these initial studies. METHODS: We perfo ... Full text Link to item Cite

The Need for Practical and Accurate Measures of Value for Radiology.

Journal Article J Am Coll Radiol · June 2019 Radiologists play a critical role in helping the health care system achieve greater value. Unfortunately, today radiology is often judged by simple "checkbox" metrics, which neither directly reflect the value radiologists provide nor the outcomes they help ... Full text Link to item Cite

Characterization of tumor mutational burden (TMB), PD-L1, and DNA repair genes to assess correlation with immune checkpoint inhibitors (ICIs) response in metastatic renal cell carcinoma (mRCC).

Conference Journal of Clinical Oncology · May 20, 2019 e16079 Background: ICIs have revolutionized treatment for mRCC; however there are limited predictive biomarkers for response to ICIs. PD-L1 status is still controversial, demonstrating little predictive utility in mRCC. TMB is pr ... Full text Cite

Immune checkpoint inhibitor response in tumors with LRP1B variants.

Conference Journal of Clinical Oncology · May 20, 2019 e14291 Background: Low-density lipoprotein receptor-related protein 1B (LRP1B) is a putative tumor suppressor gene spanning > 500 kb on chromosome 2. A melanoma study previously reported enrichment of LRP1B mutations in respon ... Full text Cite

Evaluation of tumor microenvironment and biomarkers of immune checkpoint inhibitor (ICI) response in metastatic renal cell carcinoma (mRCC).

Conference Journal of Clinical Oncology · May 20, 2019 2595 Background: ICIs are now standard of care for mRCC; however, there are few biomarkers to predict ICI response. Recent data from atezolizumab/bevacizumab trials in mRCC suggest tumors with high Teff Full text Cite

Concordance between PD-L1 assays for metastatic renal cell carcinoma (mRCC) and metastatic urothelial carcinoma (mUC).

Conference Journal of Clinical Oncology · May 20, 2019 e14259 Background: Immune checkpoint inhibitors (ICIs) are standard of care for mRCC and mUC patients (pts). PD-L1 status is gaining importance as a predictive biomarker, particularly for cisplatin-ineligible mUC. PD-L1 positivit ... Full text Cite

PROSPER: A phase III randomized study comparing perioperative nivolumab (nivo) versus observation in patients with renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN 8143).

Conference Journal of Clinical Oncology · May 20, 2019 TPS4597 Background: The anti-PD-1 antibody nivo improves overall survival (OS) in metastatic RCC and is well tolerated. There is no standard adjuvant (adjuv) systemic therapy that increases OS over surgery alone for non-metastati ... Full text Cite

The future of perioperative therapy in advanced renal cell carcinoma: how can we PROSPER?

Journal Article Future Oncol · May 2019 Patients with high-risk renal cell carcinoma (RCC) experience high rates of recurrence despite definitive surgical resection. Recent trials of adjuvant tyrosine kinase inhibitor therapy have provided conflicting efficacy results at the cost of significant ... Full text Link to item Cite

Magnetic resonance imaging features of pubic symphysis urinary fistula with pubic bone osteomyelitis in the treated prostate cancer patient.

Journal Article Abdom Radiol (NY) · April 2019 INTRODUCTION: Pubic bone osteomyelitis with pubic symphysis urinary fistula represents a debilitating complication of radiation and ablative treatments for prostate cancer. The definitive radiographic diagnosis of this clinical entity is not described. In ... Full text Link to item Cite

Cell proliferation as a biomarker for response to immune checkpoint inhibitors in highly inflamed renal cell carcinoma.

Conference Journal of Clinical Oncology · March 10, 2019 61 Background: Cell proliferation is an important marker of survival in many tumors and we hypothesized that this attribute could be related to response to immune checkpoint inhibitors in RCC. Previously we reported (SITC 2018) m ... Full text Cite

Cell proliferation as a biomarker for response to immune checkpoint inhibitors in PD-L1 negative renal cell carcinoma.

Conference Journal of Clinical Oncology · March 10, 2019 62 Background: Cell proliferation is an important marker of survival in many tumors, and we hypothesized that this attribute could be related to response to immune checkpoint inhibitors (ICIs) in RCC. Previously we reported (SITC ... Full text Cite

Evaluation of tumor microenvironment and biomarkers of immune checkpoint inhibitor (ICI) response in metastatic renal cell carcinoma (mRCC).

Conference Journal of Clinical Oncology · March 10, 2019 63 Background: ICIs are now standard of care for mRCC; however, there are few biomarkers to predict ICI response. Recent data from atezolizumab/bevacizumab trials in mRCC suggest tumors with high Teff Full text Cite

Characterization of tumor mutational burden (TMB), PD-L1, and DNA repair genes to assess correlation with immune checkpoint inhibitors (ICIs) response in metastatic renal cell carcinoma (mRCC).

Conference Journal of Clinical Oncology · March 1, 2019 589 Background: ICIs have revolutionized treatment for mRCC; however there are limited predictive biomarkers for response to ICIs. PD-L1 status is still controversial demonstrating little predictive utility in mRCC. TMB is predic ... Full text Cite

Characterization of genomic alterations as biomarkers of immune checkpoint inhibitor (ICI) response in metastatic urothelial carcinoma (mUC).

Conference Journal of Clinical Oncology · March 1, 2019 400 Background: ICIs have expanded therapeutic options for mUC patients (pts); however, biomarkers such as PD-L1 have not served as reliable predictors of treatment efficacy. High tumor mutation burden (TMB) has been previously d ... Full text Cite

Concordance between PD-L1 assays for metastatic renal cell carcinoma (mRCC) and metastatic urothelial carcinoma (mUC).

Conference Journal of Clinical Oncology · March 1, 2019 577 Background: Immune checkpoint inhibitors (ICIs) are now standard of care for mRCC and mUC patients (pts). PD-L1 status is gaining importance as a predictive biomarker, particularly for cisplatin-ineligible mUC. Four different ... Full text Cite

Evaluation of tumor microenvironment and biomarkers of immune checkpoint inhibitor (ICI) response in metastatic renal cell carcinoma (mRCC).

Conference Journal of Clinical Oncology · March 1, 2019 607 Background: ICIs are now standard of care for mRCC; however, there are few biomarkers to predict ICI response. Recent data from atezolizumab/bevacizumab trials in mRCC suggest tumors with high Teff Full text Cite

Sarcopenia in bladder cancer patients is an unmodifiable outcomes predictor.

Conference Journal of Clinical Oncology · March 1, 2019 480 Background: Sarcopenia, a severe loss of skeletal muscle mass, predicts poor outcomes in bladder cancer (BC). But, why sarcopenia occurs in BC is unknown. Our objective was to assess if diet and physical activity were the pri ... Full text Cite

PROSPER: A phase III randomized study comparing perioperative nivolumab (nivo) versus observation in patients with localized renal cell carcinoma (RCC) undergoing nephrectomy (ECOG-ACRIN 8143).

Conference Journal of Clinical Oncology · March 1, 2019 TPS684 Background: The anti-PD-1 antibody nivo improves overall survival in metastatic RCC and is well tolerated. There is no standard adjuvant systemic therapy that increases overall survival (OS) over surgery alone for non-meta ... Full text Cite

A Multireader Exploratory Evaluation of Individual Pulse Sequence Cancer Detection on Prostate Multiparametric Magnetic Resonance Imaging (MRI).

Journal Article Acad Radiol · January 2019 RATIONALE AND OBJECTIVES: To determine independent contribution of each prostate multiparametric magnetic resonance imaging (mpMRI) sequence to cancer detection when read in isolation. MATERIALS AND METHODS: Prostate mpMRI at 3-Tesla with endorectal coil f ... Full text Link to item Cite

Reduced Core Targeted (RCT) biopsy: Combining multiparametric magnetic resonance imaging - transrectal ultrasound fusion targeted biopsy with laterally-directed sextant biopsies - An alternative template for prostate fusion biopsy.

Journal Article Eur J Radiol · January 2019 PURPOSE: To introduce and assess the efficacy of a Reduced Core Targeted (RCT) biopsy template (image-targeted + laterally directed sextant biopsy) to detect clinically-significant cancer in patients with elevated PSA and a previous negative biopsy or on a ... Full text Link to item Cite

Human-machine partnership with artificial intelligence for chest radiograph diagnosis.

Journal Article NPJ Digit Med · 2019 Human-in-the-loop (HITL) AI may enable an ideal symbiosis of human experts and AI models, harnessing the advantages of both while at the same time overcoming their respective limitations. The purpose of this study was to investigate a novel collective inte ... Full text Link to item Cite

Erratum: Author Correction: Human-machine partnership with artificial intelligence for chest radiograph diagnosis.

Journal Article NPJ Digit Med · 2019 [This corrects the article DOI: 10.1038/s41746-019-0189-7.]. ... Full text Link to item Cite

Aspergillus endophthalmitis : Clinical presentations and factors determining outcomes

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · 2019 Cite

Lymphogranuloma venereum (LGV) proctocolitis mimicking rectal lymphoma.

Journal Article Radiol Case Rep · December 2018 Lymphogranuloma venereum is a sexually transmitted infection caused by serotypes L1-3 of Chlamydia trachomatis and may present as hemorrhagic proctocolitis. The diagnosis of an active infection is difficult to establish, as confirmatory testing can be unre ... Full text Link to item Cite

Three-dimensional localization and targeting of prostate cancer foci with imaging and histopathologic correlation: establishing a multidisciplinary team for quality improvement.

Journal Article Curr Opin Urol · November 2018 PURPOSE OF REVIEW: The current trend in image-based identification and characterization of prostate cancer (PCa) utilizing multiparametric MRI (mpMRI) has affected diagnostic and treatment planning in terms of targeted biopsy, risk stratification and progn ... Full text Link to item Cite

Abdominal Radiography With Digital Tomosynthesis: An Alternative to Computed Tomography for Identification of Urinary Calculi?

Journal Article Urology · October 2018 OBJECTIVE: To compare the accuracy of plain abdominal radiography (kidneys, ureter, and bladder [KUB]) with digital tomosynthesis (DT) to noncontrast computed tomography (NCCT), the gold standard imaging modality for urinary stones. Due to radiation and co ... Full text Link to item Cite

Can computer-aided diagnosis assist in the identification of prostate cancer on prostate MRI? a multi-center, multi-reader investigation.

Journal Article Oncotarget · September 18, 2018 For prostate cancer detection on prostate multiparametric MRI (mpMRI), the Prostate Imaging-Reporting and Data System version 2 (PI-RADSv2) and computer-aided diagnosis (CAD) systems aim to widely improve standardization across radiologists and centers. Ou ... Full text Link to item Cite

Factors Associated With Emergency Department Visits and Hospital Admissions After Invasive Outpatient Procedures in the Veterans Health Administration.

Journal Article JAMA Surg · August 1, 2018 This study evaluates the prevalence of postprocedure emergency department visits and admissions and the association of these outcomes with relevant patient, procedure, and facility factors. ... Full text Link to item Cite

Multiparametric Prostate MR Imaging: Impact on Clinical Staging and Decision Making.

Journal Article Urol Clin North Am · August 2018 Meaningful changes to the approach of prostate cancer staging and management have been made over the past decade with increasing demand for high-quality multiparametric MR imaging (mpMRI) of the prostate. This article focuses on the evolving paradigm of pr ... Full text Link to item Cite

Progression of Treated versus Untreated Liver Imaging Reporting and Data System Category 4 Masses after Transcatheter Arterial Embolization Therapy.

Journal Article J Vasc Interv Radiol · May 2018 PURPOSE: To compare outcomes of treated vs untreated Liver Imaging Reporting and Data System category 4 (LR-4) masses after transcatheter arterial embolization. MATERIALS AND METHODS: In 167 patients undergoing embolization for HCC from January 2005 to Dec ... Full text Link to item Cite

Platinum sensitivity in metastatic prostate cancer: does histology matter?

Journal Article Prostate Cancer Prostatic Dis · April 2018 BACKGROUND: Platinum-based chemotherapy is effective in men with neuroendocrine prostate cancer (NEPC), but it is unclear whether histology (adenocarcinoma vs. non-adenocarcinoma NEPC variants) is predictive of platinum sensitivity. Given that NEPC exists ... Full text Link to item Cite

New prostate cancer prognostic grade group (PGG): Can multiparametric MRI (mpMRI) accurately separate patients with low-, intermediate-, and high-grade cancer?

Journal Article Abdom Radiol (NY) · March 2018 PURPOSE: Our objective is to determine the accuracy of multiparametric MRI (mpMRI) in predicting pathologic grade of prostate cancer (PCa) after radical prostatectomy (RP) using simple apparent diffusion coefficient metrics and, specifically, whether mpMRI ... Full text Link to item Cite

Multiparametric Prostate MR Imaging: Impact on Clinical Staging and Decision Making.

Journal Article Radiol Clin North Am · March 2018 Meaningful changes to the approach of prostate cancer staging and management have been made over the past decade with increasing demand for high-quality multiparametric MR imaging (mpMRI) of the prostate. This article focuses on the evolving paradigm of pr ... Full text Link to item Cite

A phase III randomized study comparing perioperative nivolumab vs. observation in patients with localized renal cell carcinoma undergoing nephrectomy (PROSPER RCC).

Conference Journal of Clinical Oncology · February 20, 2018 TPS710 Background: The anti-PD-1 antibody nivolumab (nivo) improves overall survival (OS) in metastatic treatment refractory RCC and is generally tolerable. In 2017, there is no standard adjuvant therapy proven to increase OS ove ... Full text Cite

LI-RADS technical requirements for CT, MRI, and contrast-enhanced ultrasound.

Journal Article Abdom Radiol (NY) · January 2018 Accurate detection and characterization of liver observations to enable HCC diagnosis and staging using LI-RADS requires a technically adequate imaging exam. To help achieve this objective, LI-RADS has proposed technical requirements for CT, MR, and contra ... Full text Link to item Cite

Correction to: LI-RADS technical requirements for CT, MRI, and contrast-enhanced ultrasound.

Journal Article Abdom Radiol (NY) · January 2018 The original version of this article unfortunately contained mistakes in the author list. The following author names were listed without middle initial. The correct author names are: Avinash R Kambadakone, Rajan T. Gupta, Thomas A. Hope, Kathryn J. Fowler, ... Full text Link to item Cite

Correlation Between 3D ARFI and Quantitative Imaging Metrics from SWEI and Multi-Parametric MRI in Vivo in Normal and Cancerous Prostate Tissue

Conference IEEE International Ultrasonics Symposium Ius · January 1, 2018 Prostate lesions and healthy regions from 12 radical prostatectomy patients were identified in acoustic radiation force impulse (ARFI) imaging, shear wave elasticity imaging (SWEI), and multi-parametric magnetic resonance imaging (mpMRI) apparent diffusion ... Full text Cite

Correction.

Journal Article AJR Am J Roentgenol · January 2018 Full text Link to item Cite

Development of Fiber Optic Sensors for Leak Detection in Underground Energy Storage Pipelines

Conference 2018 6TH EDITION OF INTERNATIONAL CONFERENCE ON WIRELESS NETWORKS & EMBEDDED SYSTEMS (WECON) · 2018 Cite

Pilot Evaluation of Angiogenesis Signaling Factor Response after Transcatheter Arterial Embolization for Hepatocellular Carcinoma.

Journal Article Radiology · October 2017 Purpose To identify changes in a broad panel of circulating angiogenesis factors after bland transcatheter arterial embolization (TAE), a purely ischemic treatment for hepatocellular carcinoma (HCC). Materials and Methods This prospective HIPAA-compliant s ... Full text Link to item Cite

Characterization of Small Focal Renal Lesions: Diagnostic Accuracy with Single-Phase Contrast-enhanced Dual-Energy CT with Material Attenuation Analysis Compared with Conventional Attenuation Measurements.

Journal Article Radiology · September 2017 Purpose To determine whether single-phase contrast material-enhanced dual-energy material attenuation analysis improves the characterization of small (1-4 cm) renal lesions compared with conventional attenuation measurements by using histopathologic analys ... Full text Link to item Cite

Does mpMRI improve clinical criteria in selecting men with prostate cancer for active surveillance?

Journal Article Prostate Cancer Prostatic Dis · September 2017 BACKGROUND: Active surveillance (AS) has excellent short to medium term outcomes in well-selected prostate cancer patients. Traditional biopsy-based selection criteria have been criticized for inaccurate determination of cancer grade and extent. We evaluat ... Full text Link to item Cite

Transforming the Perioperative Treatment Paradigm in Non-Metastatic RCC-A Possible Path Forward.

Journal Article Kidney Cancer · July 26, 2017 In 2017, there is no adjuvant systemic therapy proven to increase overall survival in non-metastatic renal cell carcinoma (RCC). The anti-PD-1 antibody nivolumab improves overall survival in metastatic treatment refractory RCC and is generally tolerable. M ... Full text Link to item Cite

Imaging Advances in Urolithiasis.

Journal Article J Endourol · July 2017 The prevalence of urinary stones in the United States has been described as 1 in 11 persons reporting a history of stones. Imaging plays a crucial role in diagnosis, management, and follow-up for these patients and imaging technology over the last 100 year ... Full text Link to item Cite

The Contemporary Role of Multiparametric Magnetic Resonance Imaging in Active Surveillance for Prostate Cancer.

Journal Article Curr Urol Rep · July 2017 PURPOSE OF REVIEW: Growing research supports the use of multiparametric magnetic resonance imaging (mpMRI) for the evaluation of localized prostate cancer (PCa). We highlight contemporary evidence supporting its use in active surveillance (AS). RECENT FIND ... Full text Link to item Cite

A phase III randomized study comparing perioperative nivolumab vs. observation in patients with localized renal cell carcinoma undergoing nephrectomy (PROSPER RCC).

Conference Journal of Clinical Oncology · May 20, 2017 TPS4596 Background: The anti-PD-1 antibody nivolumab (nivo) improves overall survival (OS) in metastatic treatment refractory RCC and is generally tolerable. In 2017, there is no standard adjuvant therapy proven to increase OS ov ... Full text Cite

Association of neuroendocrine phenotype with platinum chemotherapy outcomes in men with metastatic prostate cancer.

Conference Journal of Clinical Oncology · May 20, 2017 e16532 Background: DNA repair defects are common in men with mCRPC, and platinum chemotherapy may have a role in selected patients. We aimed to determine whether neuroendocrine variant prostate cancer (NEPC) is associated with a ... Full text Cite

Utilization of multiparametric prostate magnetic resonance imaging in clinical practice and focal therapy: report from a Delphi consensus project.

Journal Article World J Urol · May 2017 PURPOSE: To codify the use of multiparametric magnetic resonance imaging (mpMRI) for the interrogation of prostate neoplasia (PCa) in clinical practice and focal therapy (FT). METHODS: An international collaborative consensus project was undertaken using t ... Full text Link to item Cite

Assessing clinically significant prostate cancer: Diagnostic properties of multiparametric magnetic resonance imaging compared to three-dimensional transperineal template mapping histopathology.

Journal Article Int J Urol · February 2017 OBJECTIVE: To evaluate the diagnostic properties of multiparametric magnetic resonance imaging in the detection, localization and characterization of prostate cancer using three-dimensional transperineal template mapping biopsy histopathology as the compar ... Full text Link to item Cite

Approach to evaluation of fever in ambulatory cancer patients receiving chemotherapy: A systematic review.

Journal Article Cancer Treat Rev · December 2016 PURPOSE: To define the optimal model of care for patients receiving outpatient chemotherapy who experience a fever. Fever is a common symptom in patients receiving chemotherapy, but the approach to evaluation of fever is not standardized. METHODS: We condu ... Full text Link to item Cite

Integration of multiparametric MRI into active surveillance of prostate cancer.

Journal Article Future Oncol · November 2016 Prostate cancer is the most common noncutaneous cancer in men though many men will not die of this disease and may not require definitive treatment. Active surveillance (AS) is an increasingly utilized potential solution to the issue of overtreatment of pr ... Full text Link to item Cite

Comparison between 3D ARFI imaging and mpMRI in detecting clinically-significant prostate cancer lesions

Conference IEEE International Ultrasonics Symposium Ius · November 1, 2016 Current prostate cancer screening methods involve non-targeted needle biopsies and detection of clinically-insignificant lesions that receive excessive treatments, exposing patients to unnecessary adverse side effects and placing a burden on our health car ... Full text Cite

Standardization of definitions in focal therapy of prostate cancer: report from a Delphi consensus project.

Journal Article World J Urol · October 2016 PURPOSE: To reach standardized terminology in focal therapy (FT) for prostate cancer (PCa). METHODS: A four-stage modified Delphi consensus project was undertaken among a panel of international experts in the field of FT for PCa. Data on terminology in FT ... Full text Link to item Cite

Interobserver Reproducibility of the PI-RADS Version 2 Lexicon: A Multicenter Study of Six Experienced Prostate Radiologists.

Journal Article Radiology · September 2016 Purpose To determine the interobserver reproducibility of the Prostate Imaging Reporting and Data System (PI-RADS) version 2 lexicon. Materials and Methods This retrospective HIPAA-compliant study was institutional review board-approved. Six radiologists f ... Full text Link to item Cite

Portrayal of radiology in a major medical television series: How does it influence the perception of radiology among patients and radiology professionals?

Journal Article Eur Radiol · August 2016 OBJECTIVES: To assess how the portrayal of Radiology on medical TV shows is perceived by patients and radiology professionals. METHODS: In this IRB-approved study with patient consent waived, surveys were conducted among adult patients scheduled for radiol ... Full text Link to item Cite

Defining the Incremental Utility of Prostate Multiparametric Magnetic Resonance Imaging at Standard and Specialized Read in Predicting Extracapsular Extension of Prostate Cancer.

Journal Article Eur Urol · August 2016 UNLABELLED: Multiparametric magnetic resonance imaging (mpMRI) is increasingly used in staging early prostate cancer (PCa) but remains heavily reader-dependent. We aim to define the incremental utility of mpMRI over clinical parameters in determining the p ... Full text Link to item Cite

Can Radiologic Staging With Multiparametric MRI Enhance the Accuracy of the Partin Tables in Predicting Organ-Confined Prostate Cancer?

Journal Article AJR Am J Roentgenol · July 2016 OBJECTIVE: The purpose of this study is to investigate the accuracy of multiparametric MRI with endorectal coil and Partin tables in predicting organ-confined (OC) prostate cancer in a contemporary cohort undergoing radical prostatectomy (RP) and to assess ... Full text Link to item Cite

Identifying Clinically Significant Prostate Cancers using 3-D In Vivo Acoustic Radiation Force Impulse Imaging with Whole-Mount Histology Validation.

Journal Article Ultrasound Med Biol · June 2016 Overly aggressive prostate cancer (PCa) treatment adversely affects patients and places an unnecessary burden on our health care system. The inability to identify and grade clinically significant PCa lesions is a factor contributing to excessively aggressi ... Full text Link to item Cite

Massive gas gangrene secondary to occult colon carcinoma.

Journal Article Radiol Case Rep · June 2016 Gas gangrene is a rare but often fatal soft-tissue infection. Because it is uncommon and the classic symptom of crepitus does not appear until the infection is advanced, prompt diagnosis requires a high index of suspicion. We present a case report of a mid ... Full text Link to item Cite

Multiparametric prostate MRI: focus on T2-weighted imaging and role in staging of prostate cancer.

Journal Article Abdom Radiol (NY) · May 2016 Multiparametric MRI (mpMRI) represents a growing modality for the non-invasive evaluation of prostate cancer (PCa) and is increasingly being used for patients with persistently elevated PSA and prior negative biopsies, for monitoring patients in active sur ... Full text Link to item Cite

Navigating MRI-TRUS fusion biopsy: optimizing the process and avoiding technical pitfalls.

Journal Article Expert Rev Anticancer Ther · 2016 Multi-parametric MRI (mpMRI) is widely used in the detection and characterization of clinically- significant prostate cancer. MRI-TRUS (trans-rectal ultrasound) fusion biopsy is an in-office procedure that promises to empower urologists to successfully tar ... Full text Link to item Cite

Approach to fever assessment in ambulatory cancer patients receiving chemotherapy: A clinical practice guideline

Journal Article Current Oncology · January 1, 2016 Background This guideline was prepared by the Fever Assessment Guideline Development Group, a group organized by the Program in Evidence-Based Care at the request of the Cancer Care Ontario Systemic Treatment Program. The mandate was to develop a standardi ... Full text Cite

The Contemporary Safety and Effectiveness of Lower Extremity Bypass Surgery and Peripheral Endovascular Interventions in the Treatment of Symptomatic Peripheral Arterial Disease.

Journal Article Circulation · November 24, 2015 BACKGROUND: Treatment for symptomatic peripheral artery disease includes lower extremity bypass surgery (LEB) and peripheral endovascular interventions (PVIs); however, limited comparative effectiveness data exist between the 2 therapies. We assessed the s ... Full text Link to item Cite

Effect of radiologists' experience with an adaptive statistical iterative reconstruction algorithm on detection of hypervascular liver lesions and perception of image quality.

Journal Article Abdom Imaging · October 2015 PURPOSE: To prospectively evaluate whether clinical experience with an adaptive statistical iterative reconstruction algorithm (ASiR) has an effect on radiologists' diagnostic performance and confidence for the diagnosis of hypervascular liver tumors, as w ... Full text Link to item Cite

How the radiologist can add value in the evaluation of the pre- and post-surgical pancreas.

Journal Article Abdom Imaging · October 2015 Disease involving the pancreas can be a significant diagnostic challenge to the interpreting radiologist. Moreover, the majority of disease processes involving the pancreas carry high significant morbidity and mortality either due to their natural process ... Full text Link to item Cite

Apparent Diffusion Coefficient Values of the Benign Central Zone of the Prostate: Comparison With Low- and High-Grade Prostate Cancer.

Journal Article AJR Am J Roentgenol · August 2015 OBJECTIVE: The apparent diffusion coefficient (ADC) values for benign central zone (CZ) of the prostate were compared with ADC values of benign peripheral zone (PZ), benign transition zone (TZ), and prostate cancer, using histopathologic findings from radi ... Full text Link to item Cite

Computed high b-value diffusion-weighted imaging improves lesion contrast and conspicuity in prostate cancer.

Journal Article Prostate Cancer Prostatic Dis · June 2015 BACKGROUND: To evaluate whether very high b-value computed diffusion-weighted imaging (cDWI) is able to provide better contrast between the foci of prostate cancer and background tissue than the standard apparent diffusion coefficient (ADC) map, and whethe ... Full text Link to item Cite

Nephrogenic systemic fibrosis risk after liver magnetic resonance imaging with gadoxetate disodium in patients with moderate to severe renal impairment: results of a prospective, open-label, multicenter study.

Journal Article Invest Radiol · June 2015 OBJECTIVE: The objective of this study was to assess the risk of gadoxetate disodium in liver imaging for the development of nephrogenic systemic fibrosis (NSF) in patients with moderate to severe renal impairment. MATERIALS AND METHODS: We performed a pro ... Full text Link to item Cite

Current trends and new frontiers in focal therapy for localized prostate cancer.

Journal Article Curr Urol Rep · June 2015 Prostate cancer (PCa) care is an ever-evolving field. Research and technological developments continue to refine our definitions and management of this disease. Now, with a greater understanding of the natural history of PCa, the prevention of overtreatmen ... Full text Link to item Cite

Locoregional therapy of locally advanced breast cancer: A clinical practice guideline

Journal Article Current Oncology · March 1, 2015 Questions 1. In female patients with locally advanced breast cancer (LABC) and good response to neoadjuvant chemotherapy (NACT), including endocrine therapy, what is the role of breast-conserving surgery (BCS) compared with mastectomy? 2. In female patient ... Full text Cite

Radiology reports for incidental thyroid nodules on CT and MRI: high variability across subspecialties.

Journal Article AJNR Am J Neuroradiol · February 2015 BACKGROUND AND PURPOSE: Variability in radiologists' reporting styles and recommendations for incidental thyroid nodules can lead to confusion among clinicians and may contribute to inconsistent patient care. Our aim was to describe reporting practices of ... Full text Link to item Cite

Detection of prostate cancer with multiparametric MRI (mpMRI): effect of dedicated reader education on accuracy and confidence of index and anterior cancer diagnosis.

Journal Article Abdom Imaging · January 2015 PURPOSE: To evaluate the impact of dedicated reader education on accuracy/confidence of peripheral zone index cancer and anterior prostate cancer (PCa) diagnosis with mpMRI; secondary aim was to assess the ability of readers to differentiate low-grade canc ... Full text Link to item Cite

B-mode and acoustic radiation force impulse (ARFI) imaging of prostate zonal anatomy: comparison with 3T T2-weighted MR imaging.

Journal Article Ultrason Imaging · January 2015 Prostate cancer (PCa) is the most common non-cutaneous malignancy among men in the United States and the second leading cause of cancer-related death. Multi-parametric magnetic resonance imaging (mpMRI) has gained recent popularity to characterize PCa. Aco ... Full text Link to item Cite

Practice and quality improvement: successful implementation of TeamSTEPPS tools into an academic interventional ultrasound practice.

Journal Article AJR Am J Roentgenol · January 2015 OBJECTIVE: The goal of this study was to implement an evidence-based teamwork system to improve communication and teamwork skills among health care professionals (TeamSTEPPS) into an academic interventional ultrasound program and to assess safety and team- ... Full text Link to item Cite

Recent Developments in Multiparametric Prostate MR Imaging

Journal Article Current Radiology Reports · December 14, 2014 Multiparametric magnetic resonance imaging (mpMRI) of the prostate has become a mature and accepted technology in the evaluation of the patient with suspected prostate cancer (PCa). This review focuses on key recent developments in the area of mpMRI, speci ... Full text Cite

Overview of Classification Systems in Peripheral Artery Disease

Journal Article Seminars in Interventional Radiology · November 14, 2014 Full text Cite

Treatment of Infrapopliteal Arterial Occlusive Disease in Critical Limb Ischemia

Journal Article Seminars in Interventional Radiology · November 14, 2014 Full text Cite

Comparing 3-T multiparametric MRI and the Partin tables to predict organ-confined prostate cancer after radical prostatectomy.

Journal Article Urol Oncol · November 2014 OBJECTIVES: The purpose of our study was to test our hypothesis that multiparametric magnetic resonance imaging (mpMRI) may have a higher prognostic accuracy than the Partin tables in predicting organ-confined (OC) prostate cancer and extracapsular extensi ... Full text Link to item Cite

Retrospective assessment of the utility of an iron-based agent for contrast-enhanced magnetic resonance venography in patients with endstage renal diseases.

Journal Article J Magn Reson Imaging · July 2014 PURPOSE: To compare abdominopelvic and lower extremity venous enhancement in contrast-enhanced magnetic resonance venography (ceMRV), using iron-based ferumoxytol and gadolinium-based gadofosveset. MATERIALS AND METHODS: This was a Health Insurance Portabi ... Full text Link to item Cite

The role of magnetic resonance imaging (MRI) in focal therapy for prostate cancer: recommendations from a consensus panel.

Journal Article BJU Int · February 2014 OBJECTIVE: To establish a consensus on the utility of multiparametric magnetic resonance imaging (mpMRI) to identify patients for focal therapy. METHODS: Urological surgeons, radiologists, and basic researchers, from Europe and North America participated i ... Full text Link to item Cite

Multimodality approach to detection and characterization of hepatic hemangiomas

Chapter · January 1, 2014 Hemangiomas are the most common benign hepatic tumor and represent a common incidental finding on routine imaging examinations of the liver. The majority of hemangiomas demonstrate classical imaging findings on grayscale ultrasound (US), multidetector-row ... Full text Cite

Abdominal Trauma

Chapter · January 1, 2014 Full text Cite

Voltage Level Increment by Proposed Sub-Cell for Existing Topologies

Conference 2014 IEEE INNOVATIVE SMART GRID TECHNOLOGIES - ASIA (ISGT ASIA) · 2014 Cite

Clinical impact of an adaptive statistical iterative reconstruction algorithm for detection of hypervascular liver tumours using a low tube voltage, high tube current MDCT technique.

Journal Article Eur Radiol · December 2013 OBJECTIVES: To investigate the impact of an adaptive statistical iterative reconstruction (ASiR) algorithm on diagnostic accuracy and confidence for the diagnosis of hypervascular liver tumours, as well as the reader's perception of image quality, using a ... Full text Link to item Cite

Automated patient-tailored screening of the liver for diffuse steatosis and iron overload using MRI.

Journal Article AJR Am J Roentgenol · September 2013 OBJECTIVE: The purpose of this article is to validate an automated screening method for evaluation of hepatic steatosis or siderosis. MATERIALS AND METHODS: This was a two-part study, with retrospective and prospective portions. First, 130 consecutive abdo ... Full text Link to item Cite

Abdominopelvic and lower extremity deep venous thrombosis: evaluation with contrast-enhanced MR venography with a blood-pool agent.

Journal Article AJR Am J Roentgenol · July 2013 OBJECTIVE: The purpose of this article is to evaluate contrast-enhanced (CE) MR venography (MRV) with a blood-pool agent for detection of abdominopelvic and lower extremity deep venous thrombosis (DVT) compared with a conventional unenhanced gradient-recal ... Full text Link to item Cite

MRI assessment of biliary ductal obstruction: is there added value of T1-weighted gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced MR cholangiography?

Journal Article AJR Am J Roentgenol · July 2013 OBJECTIVE: The goal of the present study was to determine the added value of gadolium-ethoxybenzyl-diethylenetriamine pentaacetic acid (gadoxetate disodium)-enhanced magnetic resonance cholangiography (MRC) to standard liver MRI including T2-weighted MRCP ... Full text Link to item Cite

The state of prostate MRI in 2013.

Journal Article Oncology (Williston Park) · April 2013 Compared with earlier prostate MRI techniques that suffered from relatively poor sensitivity and specificity for detecting prostate cancer because of their reliance predominantly on morphology, multiparametric prostate MRI (mpMRI) in 2013 provides a wealth ... Link to item Cite

The state of prostate MRI in 2013.

Journal Article Oncology (Williston Park, N.Y.) · April 1, 2013 Compared with earlier prostate MRI techniques that suffered from relatively poor sensitivity and specificity for detecting prostate cancer because of their reliance predominantly on morphology, multiparametric prostate MRI (mpMRI) in 2013 provides a wealth ... Cite

Lesion detection and assessment of extrahepatic findings in abdominal MRI using hepatocyte specific contrast agents--comparison of Gd-EOB-DTPA and Gd-BOPTA.

Journal Article BMC Med Imaging · March 18, 2013 BACKGROUND: To evaluate the contrast agent performance of Gd-EOB-DTPA and Gd-BOPTA for detection and assessment of extrahepatic findings, semi-quantitatively and qualitatively. METHODS: 13 patients with 19 extrahepatic lesions underwent liver MRI with Gd-E ... Full text Link to item Cite

Quantitative dynamic contrast-enhanced MRI of pelvic and lumbar bone marrow: effect of age and marrow fat content on pharmacokinetic parameter values.

Journal Article AJR Am J Roentgenol · March 2013 Featured Publication OBJECTIVE: The purpose of this study was to determine the effects of age and fat content on quantitative dynamic contrast-enhanced MRI (DCE-MRI) parameters in the bone marrow of the lumbar spine and pelvis. The interreader reproducibility of this technique ... Full text Link to item Cite

Hepatocellular carcinoma in a North American population: does hepatobiliary MR imaging with Gd-EOB-DTPA improve sensitivity and confidence for diagnosis?

Journal Article J Magn Reson Imaging · February 2013 Featured Publication PURPOSE: To evaluate the value of hepatobiliary phase imaging for detection and characterization of hepatocellular carcinoma (HCC) in liver MRI with Gd-EOB-DTPA, in a North American population. MATERIALS AND METHODS: One hundred MRI examinations performed ... Full text Link to item Cite

Dichorionic, diamnionic twin pregnancy discordant for anencephaly: Report of two cases and literature review.

Journal Article Radiol Case Rep · 2013 Anencephaly is a lethal diagnosis. In the unique situation of a twin pregnancy discordant for anencephaly, early ultrasound diagnosis based on the discrepancy in the appearance of the heads can facilitate management and potentially decrease morbidity and m ... Full text Link to item Cite

Evaluation of the biliary tree and gallbladder with hepatocellular MR contrast agents.

Journal Article Curr Probl Diagn Radiol · 2013 Featured Publication Newer hepatobiliary magnetic resonance (MR) contrast agents allow the ability to combine the anatomical information from T2-weighted magnetic resonance cholangiopancreatography with functional information derived from contrast-enhanced T1-weighted magnetic ... Full text Link to item Cite

Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis.

Journal Article J Comput Assist Tomogr · 2013 OBJECTIVE: This study aimed to determine whether visible bone marrow enhancement (BME) at pelvic magnetic resonance angiography (MRA) correlates with anemia. METHODS: This is an institutional review board-approved, Health Insurance Portability and Accounta ... Full text Link to item Cite

Radiologic-pathologic correlation of uncommon mesenchymal liver tumors.

Journal Article Curr Probl Diagn Radiol · 2013 Mesenchymal liver tumors are rarely encountered in clinical practice. We review the spectrum of mesenchymal liver tumors with radiologic-pathologic correlation. There is an overlap of cross-sectional imaging findings of mesenchymal liver tumors with that o ... Full text Link to item Cite

Nodular regenerative hyperplasia in the setting of Budd-Chiari syndrome: Application of MR with hepatobiliary contrast agents and histologic confirmation

Journal Article Journal of Surgical Radiology · December 21, 2012 Overview: Nodular regenerative hyperplasia in the setting of Budd-Chiari syndrome is an uncommon benign finding but critical to diagnose accurately. Its imaging appearance of hyperenhancing lesions on arterial phase imaging on a background of chronic liver ... Cite

Hepatic hemangiomas: difference in enhancement pattern on 3T MR imaging with gadobenate dimeglumine versus gadoxetate disodium.

Journal Article Eur J Radiol · October 2012 Featured Publication PURPOSE: To compare intraindividual differences in enhancement pattern of hepatic hemangiomas between gadobenate dimeglumine (Gd-BOPTA) and gadoxetate disodium (Gd-EOB-DTPA)-enhanced 3T MR imaging. MATERIALS AND METHODS: This is a HIPAA-compliant, IRB-appr ... Full text Link to item Cite

Hepatocellular MR contrast agents: enhancement characteristics of liver parenchyma and portal vein after administration of gadoxetic acid in comparison to gadobenate dimeglumine.

Journal Article Eur J Radiol · September 2012 Featured Publication PURPOSE: To investigate the enhancement characteristics of liver parenchyma and portal vein as well as the portal vein-to liver contrast in Gd-EOB-DTPA- and Gd-BOPTA-enhanced abdominal MRI. MATERIALS AND METHODS: The local institutional review board approv ... Full text Link to item Cite

Gradient shimming during magnetic resonance imaging of the liver: comparison of a standard protocol versus a novel reduced protocol.

Journal Article Invest Radiol · September 2012 Featured Publication PURPOSE: The aim of this study was to examine the effect of minimizing prescan adjustments on table time and image quality in magnetic resonance imaging (MRI) of the liver. MATERIALS AND METHODS: This prospective Health Insurance Portability and Accountabi ... Full text Link to item Cite

Diagnosis of focal nodular hyperplasia with MRI: multicenter retrospective study comparing gadobenate dimeglumine to gadoxetate disodium.

Journal Article AJR Am J Roentgenol · July 2012 Featured Publication OBJECTIVE: The purpose of this article is to report the results from a multicenter retrospective MRI study comparing gadobenate dimeglumine and gadoxetate disodium for diagnosis of hepatic focal nodular hyperplasia (FNH). MATERIALS AND METHODS: Thirty pati ... Full text Link to item Cite

Functional evaluation of cystic duct patency with Gd-EOB-DTPA MR imaging: an alternative to hepatobiliary scintigraphy for diagnosis of acute cholecystitis?

Journal Article Abdom Imaging · June 2012 Featured Publication PURPOSE: To determine if MR cholangiography with Gd-EOB-DTPA can be used to assess cystic duct patency and to establish normal time range for reflux of contrast material into the cystic duct/gallbladder. MATERIALS AND METHODS: This retrospective study is H ... Full text Link to item Cite

MDCT evaluation of the pancreas: nuts and bolts.

Journal Article Radiol Clin North Am · May 2012 Featured Publication Multidetector-row CT (MDCT) imaging of the pancreas has important roles in diagnosis, staging, and treatment monitoring of a vast array of pancreatic diseases. Optimizing MDCT protocols not only requires an understanding of expected pathologies but also mu ... Full text Link to item Cite

Characterization of adrenal nodules with dual-energy CT: can virtual unenhanced attenuation values replace true unenhanced attenuation values?

Journal Article AJR Am J Roentgenol · April 2012 Featured Publication OBJECTIVE: The purpose of our study was to investigate whether virtual unenhanced adrenal nodule attenuation values can replace true noncontrast attenuation values. MATERIALS AND METHODS: Twenty-three incidentally discovered adrenal nodules (19 adenomas an ... Full text Link to item Cite

Liver MRI in the hepatocyte phase with gadolinium-EOB-DTPA: does increasing the flip angle improve conspicuity and detection rate of hypointense lesions?

Journal Article J Magn Reson Imaging · March 2012 Featured Publication PURPOSE: To compare conspicuity and detection rate of hypointense lesions on T1-weighted (T1w) gradient echo (GRE) sequences with low and high flip angles (FA) in hepatocyte phase magnetic resonance imaging (MRI) using gadoxetate disodium. MATERIALS AND ME ... Full text Link to item Cite

Contrast enhanced liver MRI in patients with primary sclerosing cholangitis: inverse appearance of focal confluent fibrosis on delayed phase MR images with hepatocyte specific versus extracellular gadolinium based contrast agents.

Journal Article Acad Radiol · December 2011 Featured Publication RATIONALE AND OBJECTIVES: To assess the enhancement pattern of focal confluent fibrosis (FCF) on contrast-enhanced hepatic magnetic resonance imaging (MRI) using hepatocyte-specific (Gd-EOB-DTPA) and extracellular (ECA) gadolinium-based contrast agents in ... Full text Link to item Cite

Methodology to register prostate B-mode and ARFI images to MR and histology

Conference IEEE International Ultrasonics Symposium Ius · December 1, 2011 Acoustic Radiation Force Impulse (ARFI) imaging is being developed for guiding needle biopsy and focal therapy of Prostate cancer (PCa). In vivo ARFI images portray internal structures in the prostate with higher contrast than matched B-mode images. Given ... Full text Cite

PET appearance of tuberculous empyema necessitans.

Journal Article Clin Nucl Med · October 2011 Featured Publication Full text Link to item Cite

Hepatobiliary transit times of gadoxetate disodium (Primovist®) for protocol optimization of comprehensive MR imaging of the biliary system--what is normal?

Journal Article Eur J Radiol · August 2011 Featured Publication OBJECTIVE: The purpose of this study was to determine transit times for excretion of Gd-EOB-DTPA into different segments of the hepatobiliary system in patients with normal liver function. METHODS: This retrospective study was IRB approved with a waiver of ... Full text Link to item Cite

Effect of organ enhancement and habitus on estimation of unenhanced attenuation at contrast-enhanced dual-energy MDCT: concepts for individualized and organ-specific spectral iodine subtraction strategies.

Journal Article AJR Am J Roentgenol · May 2011 Featured Publication OBJECTIVE: The purpose of this study was to assess whether habitus and organ enhancement influence iodine subtraction and should be incorporated into spectral subtraction algorithms. SUBJECTS AND METHODS: This study included 171 patients. In the unenhanced ... Full text Link to item Cite

Detection of renal lesion enhancement with dual-energy multidetector CT.

Journal Article Radiology · April 2011 Featured Publication PURPOSE: To determine whether dual-energy multidetector CT enables detection of renal lesion enhancement by using calculated nonenhanced images with spectral-based extraction in a non-body weight-restricted patient population. MATERIALS AND METHODS: Betwee ... Full text Link to item Cite

Gadoxetate disodium-enhanced hepatic MRI: dose-dependent contrast dynamics of hepatic parenchyma and portal vein.

Journal Article AJR Am J Roentgenol · January 2011 Featured Publication OBJECTIVE: The purpose of this study was to investigate the relative enhancement characteristics of the hepatic parenchyma and portal vein during gadoxetate disodium-enhanced abdominal MRI and to assess whether contrast between the portal vein and the hepa ... Full text Link to item Cite

Successful endovascular management of a transected horseshoe kidney

Journal Article Journal of Surgical Radiology · January 1, 2011 Overview: The horseshoe kidney is more prone to blunt abdominal trauma because of its low position and the presence of the isthmus across the midline. This is a rare case of complete transection of a horseshoe kidney at the isthmus due to blunt abdominal t ... Cite

Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents.

Journal Article AJR Am J Roentgenol · August 2010 Featured Publication OBJECTIVE: The objective of our study was to illustrate how the properties of hepatocyte-specific MR contrast agents can be used in the dynamic evaluation of the biliary system. CONCLUSION: Because of their dual route of excretion through the kidneys and t ... Full text Link to item Cite

Comparative Evaluation of Topical and Electronic Anesthesia During Scaling and Root Planing

Journal Article Journal of Periodontology · July 2010 Background: Scaling and root planing (SRP) in periodontitis is considered to be painful and thus requires anesthesia. The present study evaluates the effectiveness of a eutectic mixture of 25 mg/g lignocaine plus 25 mg/g pril ... Full text Cite

Dual-energy CT for characterization of adrenal nodules: initial experience.

Journal Article AJR Am J Roentgenol · June 2010 Featured Publication OBJECTIVE: The purpose of this study was to determine whether use of dual-energy technique can improve the diagnostic performance of CT in the differential diagnosis of adrenal adenomas and metastatic lesions. SUBJECTS AND METHODS: Thirty-one adrenal nodul ... Full text Link to item Cite

Respiratory-triggered three-dimensional T2-weighted MR cholangiography after injection of gadoxetate disodium: is it still reliable?

Journal Article Radiology · May 2010 Featured Publication PURPOSE: To test the null hypothesis that there is no quantitative or qualitative difference between respiratory-triggered three-dimensional (3D) T2-weighted magnetic resonance (MR) cholangiography performed before or after administration of gadoxetate dis ... Full text Link to item Cite

May-Thurner Syndrome Complicating Left-Sided Renal Transplant

Journal Article Transplantation · April 15, 2010 Full text Cite

New developments in massive transfusion in trauma

Journal Article Current Opinion in Anaesthesiology · April 2010 Full text Cite

Dual-energy multidetector CT: how does it work, what can it tell us, and when can we use it in abdominopelvic imaging?

Journal Article Radiographics · 2010 Featured Publication Dual-energy CT provides information about how substances behave at different energies, the ability to generate virtual unenhanced datasets, and improved detection of iodine-containing substances on low-energy images. Knowing how a substance behaves at two ... Full text Link to item Cite

D-dimers and efficacy of clinical risk estimation algorithms: sensitivity in evaluation of acute pulmonary embolism.

Journal Article AJR Am J Roentgenol · August 2009 Featured Publication OBJECTIVE: The goal of this study was to test the efficacy of clinical risk algorithms and a quantitative immunoturbidimetric D-dimer assay in the evaluation of patients undergoing pulmonary CT angiography for suspected acute pulmonary embolism. SUBJECTS A ... Full text Link to item Cite

Subchronic toxicity study of urea molasses mineral block in kids

Journal Article Veterinary Research Communications · February 2009 Full text Cite

MRI of the Hepatobiliary System with a Liver-Specific Contrast Agent

Conference AMERICAN JOURNAL OF ROENTGENOLOGY · 2009 Cite

Lisfranc injury: imaging findings for this important but often-missed diagnosis.

Journal Article Curr Probl Diagn Radiol · 2008 Featured Publication The Lisfranc injury is a popular topic in the radiology, orthopedic surgery, and emergency medicine literature, primarily due to the subtleties of the radiographic findings and potentially dire consequences of missed diagnoses. The purpose of this article ... Full text Link to item Cite

Changes in the American Interventional Radiology Literature: Comparison over a 10-Year Time Period

Journal Article CardioVascular and Interventional Radiology · August 2006 Full text Cite

Clinical evaluation of a bioresorbable membrane (polyglactin 910) in the treatment of miller type II gingival recession

Journal Article INTERNATIONAL JOURNAL OF PERIODONTICS & RESTORATIVE DENTISTRY · 2006 Cite

Trunk kinematics and the influence on valgus knee stress in persons with high sacral level myelomeningocele.

Journal Article J Pediatr Orthop · 2005 Historically, trunk movement has been thought to be reactionary to lower body motions. The excessive trunk movement in patients with myelomeningocele may be a primary mechanism during ambulation. The purpose of this study was to quantify three-dimensional ... Full text Link to item Cite

Changes in skeletal muscle cross sectional area (CSA) in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with enzalutamide (ENZ).

Journal Article Journal of Clinical Oncology Background: Phase III studies that led to ENZ approval in the treatment of mCRPC included side effects like fatigue, musculoskeletal pain, and falls, which could result from skeletal muscle loss. Such muscle loss (sarcopenia), in a variety of cancer popula ... Full text Link to item Cite