Scholars@Duke
Sandra Sue Stinnett

Sandra Sue Stinnett

Associate Professor Emeritus of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Biostatistics
stinn001@mc.duke.edu
Duke Box 3802, Durham, NC 27710
2351 Erwin Road, Eye Center, Durham, NC 27705

Selected Publications

The Anatomy of Lower Eyelid Fat Pad Vasculature as Found in Lower Eyelid Blepharoplasties.

Journal Article Ophthalmic Plast Reconstr Surg · January 2026 PURPOSE: The vasculature within the lower eyelid fat pads in bilateral lower eyelid blepharoplasty (BLLB) surgery is not well described. Characterization of vasculature may help prevent excessive bleeding by describing the locations where pre-emptive caute ... Full text Link to item Cite

Biomarkers.

Journal Article Alzheimers Dement · December 2025 BACKGROUND: We assessed differences in retinal structure and microvasculature among individuals with Alzheimer's disease (AD), APOE ε4 carriers, and APOE ε4 noncarriers. METHOD: Participants underwent cognitive evaluation with Mini-Mental State Examination ... Full text Link to item Cite

Relative exophthalmos in facial nerve palsy.

Journal Article Can J Ophthalmol · October 2025 OBJECTIVE: While ocular manifestations of facial nerve palsy, such as lagophthalmos are well known, there is limited knowledge on whether CN 7 palsy impacts globe positioning and its implications on symptoms and management. We hypothesize that CN 7 palsy i ... Full text Link to item Cite

Retinal Layer Thickness and Volume Measurements in Traumatic Brain Injury.

Journal Article J Vitreoretin Dis · September 3, 2025 Purpose: To assess retinal layer thickness and volume by optical coherence tomography (OCT) in patients with prior traumatic brain injury (TBI). Methods: Adults (≥18 years) with prior TBI were prospectively recruited. 512 × 128-mm macular cube scans were o ... Full text Link to item Cite

Association of National Eye Institute Visual Function Questionnaire 39 Scores With Visual Function in Age-related Macular Degeneration Over 24 Months.

Journal Article Ophthalmic Surg Lasers Imaging Retina · September 2025 BACKGROUND AND OBJECTIVE: The aim of this study was to determine the National Eye Institute Visual Function Questionnaire 39 (NEI-VFQ39) score association with visual function (VF) tests in early (eAMD) and intermediate (iAMD) age-related macular degenerat ... Full text Link to item Cite

Contemporary diversity trends among matched ophthalmology residents in the USA.

Journal Article BMJ Lead · July 2, 2025 BACKGROUND: Ophthalmology remains one of the least diverse medical specialties, despite ongoing efforts to promote inclusion. To address the gap in recent literature and understand the demographic trajectory of this specialty, this study analyses current d ... Full text Link to item Cite

Dopaminergic Therapies May Decrease Risk of Early and Intermediate Non-exudative Age-related Macular Degeneration Progression.

Journal Article Ophthalmic Surg Lasers Imaging Retina · July 2025 BACKGROUND AND OBJECTIVE: Age-related macular degeneration (AMD) is a leading cause of vision loss, with progression to geographic atrophy (GA) posing a significant challenge. This study aimed to assess whether dopaminergic therapies (DMTs) reduce risk of ... Full text Link to item Cite

Correlating retinal and choroidal vascular parameters with volumetric MRI in Alzheimer's disease and amnestic mild cognitive impairment.

Journal Article BMC Ophthalmol · July 1, 2025 BACKGROUND: We assess the relationships between retinal and choroidal structural and microvascular parameters and brain volumetric magnetic resonance imaging (MRI) parameters in individuals with amnestic mild cognitive impairment (aMCI) and Alzheimer's dis ... Full text Link to item Cite

Perceived feasibility of a multicomponent prenatal intervention on childhood vaccinations: Findings from a national cross-sectional survey of prenatal care providers, April-June 2022.

Journal Article Int J Gynaecol Obstet · June 2025 BACKGROUND: There are inadequate proactive interventions that take advantage of medical contacts during pregnancy to build confidence in vaccines recommended for children after birth. In addition, prenatal providers' perceptions on implementing such proact ... Full text Link to item Cite

Characteristics Associated With Endowed Chair Titles Among U.S. Academic Ophthalmologists.

Journal Article Cureus · June 2025 INTRODUCTION: Over the last several decades, the number of women in ophthalmology has gradually increased. However, studies have demonstrated that far fewer women than men are represented in senior leadership positions. Having an endowed chair facilitates ... Full text Link to item Cite

Trends in Choroidal Vascularity Index in Cognitively Normal Individuals.

Journal Article Retina · March 4, 2025 PURPOSE: To establish a normative database of choroidal vascularity index (CVI) in cognitively normal adults. METHODS: Cognitively healthy volunteers who had a Montreal Cognitive Assessment (MoCA) score of 23 or higher were included. Exclusion criteria inc ... Full text Link to item Cite

Comparative Evaluation of the Corneal Sensitivity Thresholds between the Novel Non-Contact and Cochet-Bonnet Esthesiometers.

Journal Article Am J Ophthalmol · March 2025 PURPOSE: Primarily, to evaluate the repeatability and reproducibility of the new noncontact esthesiometer (NCE) in healthy subjects. Secondarily, the corneal sensitivity threshold measurements of the NCE were compared with those of the Cochet-Bonnet esthes ... Full text Link to item Cite

Diabetic Retinopathy Disease Burden in Patients With Lower Household Incomes vs Higher Household Incomes.

Journal Article J Vitreoretin Dis · January 7, 2025 Purpose: To assess the differences in measures of diabetic retinopathy (DR) disease burden between patients in high-income vs low-income ZIP codes when presenting to retina specialists. Methods: This retrospective cohort study comprised patients who presen ... Full text Link to item Cite

Evaluating the Impact of Gender and Race on Otolaryngology Resident Experiences Across the United States.

Journal Article Otolaryngol Head Neck Surg · January 2025 OBJECTIVE: Otolaryngology residents often encounter work-related stress and challenges during training. Sociodemographic factors influence experiences during residency; however, the impact of race and gender on otolaryngology trainee well-being during resi ... Full text Link to item Cite

Glaucoma Surgery SOS: Emergency Department Utilization Greater among Younger and First-Time Surgical Patients with Glaucoma.

Journal Article Ophthalmol Glaucoma · 2025 PURPOSE: To describe the frequency, findings, and interventions of patients' emergency department (ED) visits after all types of glaucoma surgery DESIGN: Retrospective cohort study SUBJECTS: All surgical patients with glaucoma between 2013 and 2021 METHODS ... Full text Link to item Cite

The Duke Baerveldt 350 Versus Ahmed ClearPath 350 Study (DBACS): A Randomized Control Trial In Adults With Medically Refractory Glaucoma.

Journal Article Clin Ophthalmol · 2025 PURPOSE: To compare the efficacy and safety profile of two non-valved glaucoma drainage devices (GDDs). PATIENTS & METHODS: In this randomized control trial, patients with medically refractory glaucoma needing surgical intervention were randomized for plac ... Full text Link to item Cite

Hypoxia-mediated rescue of retinal ganglion cells deficient in mitochondrial complex I is independent of the hypoxia-inducible factor pathway.

Journal Article Sci Rep · October 15, 2024 Continuous exposure to environmental hypoxia (11% O2) has been shown to markedly slow the progressive degeneration of retinal ganglion cells (RGCs) in a mouse model of mitochondrial optic neuropathy with RGC-specific deletion of the key mitochondrial compl ... Full text Link to item Cite

Deep-learning based analysis of in-vivo confocal microscopy images of the subbasal corneal nerve plexus' inferior whorl in patients with neuropathic corneal pain and dry eye disease.

Journal Article Ocul Surf · October 2024 PURPOSE: To evaluate and compare subbasal corneal nerve parameters of the inferior whorl in patients with dry eye disease (DED), neuropathic corneal pain (NCP), and controls using a novel deep-learning-based algorithm to analyze in-vivo confocal microscopy ... Full text Link to item Cite

Ocular Mucous Membrane Pemphigoid: The Effect of Risk Factors at Presentation on Treatment Outcomes.

Journal Article Ophthalmology · September 2024 PURPOSE: Analyze the influence of risk factors at presentation in the long-term immunosuppressive therapy (IMT) outcomes of ocular mucous membrane pemphigoid (OMMP). DESIGN: Retrospective multicenter study. PARTICIPANTS: Patients with OMMP seen at the Duke ... Full text Link to item Cite

Repeatability and reproducibility of quantitative OCT angiography measurements from table-top and portable Flex Spectralis devices.

Journal Article Graefes Arch Clin Exp Ophthalmol · June 2024 PURPOSE: The recent development of a portable investigational handheld OCT-angiography (OCTA) device has allowed for expansion of imaging into the operating room (OR) in addition to standard in-clinic imaging. The aim of this study was to assess intravisit ... Full text Link to item Cite

The Effect of Bimatoprost Implant on Glaucoma Patients: An Observational Study.

Journal Article J Glaucoma · June 1, 2024 PRCIS: In this retrospective study of glaucoma patients receiving the bimatoprost implant at Duke Eye Center, the number of topical intraocular pressure-lowering medications was significantly reduced through 12 months after the implant. PURPOSE: To study t ... Full text Link to item Cite

Spiral scanning improves subject fixation in widefield retinal imaging.

Journal Article Opt Lett · May 1, 2024 Point scanning retinal imaging modalities, including confocal scanning light ophthalmoscopy (cSLO) and optical coherence tomography, suffer from fixational motion artifacts. Fixation targets, though effective at reducing eye motion, are infeasible in some ... Full text Link to item Cite

Peripapillary Optical Coherence Tomography Angiography in Alzheimer's Disease, Mild Cognitive Impairment, and Normal Cognition.

Journal Article Ophthalmic Surg Lasers Imaging Retina · February 2024 OBJECTIVE: This study aimed to identify peripapillary microvascular changes in Alzheimer's disease (AD) and mild cognitive impairment (MCI). PATIENTS AND METHODS: In this prospective study, 66 eyes of 36 subjects with AD, 119 eyes of 63 with MCI, and 513 e ... Full text Link to item Cite

Gradeability and Reproducibility of Geographic Atrophy Measurement in GATHER-1, a Phase II/III Randomized Interventional Trial.

Journal Article Ophthalmol Sci · 2024 OBJECTIVE: To validate GATHER-1 inclusion criteria and the study's primary anatomic end point by assessing the reproducibility of geographic atrophy (GA) measurements and factors that affect reproducibility. DESIGN: Post hoc analysis of phase II/III clinic ... Full text Link to item Cite

Acute, Treatment-Naïve Branch Retinal Vein Occlusion in Younger Individuals: Risk Factors and Clinical Outcomes.

Journal Article J Vitreoretin Dis · 2024 Purpose: To compare the risk factors and clinical outcomes in patients younger than 50 years with acute, treatment-naïve branch retinal vein occlusion (BRVO) with outcomes in patients 50 years or older. Methods: Patients diagnosed with acute, treatment-naï ... Full text Link to item Cite

Differences in Retinal and Choroidal Microvasculature and Structure in Dementia With Lewy Bodies Compared With Normal Cognition.

Journal Article J Vitreoretin Dis · 2024 Purpose: To evaluate the retinal and choroidal microvasculature and structure in individuals with dementia with Lewy bodies (DLB) compared with controls with normal cognition using optical coherence tomography (OCT) and OCT angiography (OCTA). Methods: An ... Full text Open Access Link to item Cite

Chronic Effects of e-Cigarette Aerosol Inhalation on Macular Perfusion Assessed Using OCT Angiography.

Journal Article J Vitreoretin Dis · 2024 Purpose: To determine whether there are significant differences in the microvasculature and central retinal thickness (CRT) between e-cigarette users (user group) and age-matched nonusers (control group) using optical coherence tomography angiography (OCTA ... Full text Link to item Cite

Characterizing differences in retinal and choroidal microvasculature and structure in individuals with Huntington's Disease compared to healthy controls: A cross-sectional prospective study.

Journal Article PLoS One · 2024 OBJECTIVE: To characterize retinal and choroidal microvascular and structural changes in patients who are gene positive for mutant huntingtin protein (mHtt) with symptoms of Huntington's Disease (HD). METHODS: This study is a cross-sectional comparison of ... Full text Link to item Cite

Impact of Bariatric Surgery on Treatment Burden and Progression of Diabetic Retinopathy.

Journal Article J Vitreoretin Dis · 2024 Purpose: To assess the severity, progression, and treatment burden of diabetic retinopathy (DR) in patients after bariatric surgery compared with controls. Methods: A retrospective cohort study was performed of patients with type 2 diabetes and DR seen at ... Full text Link to item Cite

Analysis of the Retinal and Choroidal Vasculature Using Ultrawidefield Fundus Imaging in Mild Cognitive Impairment and Normal Cognition.

Journal Article Ophthalmol Sci · 2024 PURPOSE: To utilize ultrawidefield (UWF) imaging to evaluate retinal and choroidal vasculature and structure in individuals with mild cognitive impairment (MCI) compared with that of controls with normal cognition. DESIGN: Prospective cross sectional study ... Full text Link to item Cite

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Journal Article Ophthalmol Sci · 2024 Full text Link to item Cite

Longitudinal Assessment of Peripapillary Microvasculature Using Optical Coherence Tomography Angiography in Cognitively Normal Adults.

Journal Article J Vitreoretin Dis · 2024 Introduction: To evaluate longitudinal peripapillary changes in cognitively normal older adults using optical coherence tomography (OCT) and OCT angiography (OCTA). Methods: Participants older than 50 years with no history of neurodegenerative disease or c ... Full text Link to item Cite

Macular, Choroidal, and Peripapillary Perfusion Changes in Mild and Moderate Traumatic Brain Injury Using Optical Coherence Tomography and Angiography.

Journal Article J Vitreoretin Dis · 2024 Introduction: To compare the retinal and choroidal architecture and microvasculature between patients with mild or moderate traumatic brain injury (TBI) and controls with normal cognition using optical coherence tomography (OCT) and OCT angiography (OCTA). ... Full text Link to item Cite

Angioarchitectural alterations in the retina and choroid in frontotemporal dementia.

Journal Article PLoS One · 2024 OBJECTIVE: Frontotemporal dementia (FTD) is a progressive neurodegenerative disorder that affects the frontal and temporal lobes of the brain, leading to cognitive decline and personality changes. The objective of this cross-sectional study was to characte ... Full text Open Access Link to item Cite

An ADaptivE PrenaTal (ADEPT) intervention to increase childhood vaccinations: Protocol for a cluster randomized trial and nested mixed methods evaluation.

Journal Article PLoS One · 2024 BACKGROUND: There is limited evidence to assess if interventions implemented during pregnancy proactively mitigate parental vaccine hesitancy and promote timely vaccination among children after birth. This study protocol describes the evaluation of an ADap ... Full text Link to item Cite

Correction: Angioarchitectural alterations in the retina and choroid in frontotemporal dementia.

Journal Article PLoS One · 2024 [This corrects the article DOI: 10.1371/journal.pone.0312118.]. ... Full text Link to item Cite

Reduced Retinal Vessel and Perfusion Densities in Multiple Sclerosis compared to Controls

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · 2024 Cite

Longitudinal Analysis of Retinal Microvascular and Choroidal Imaging Parameters in Parkinson's Disease Compared with Controls.

Journal Article Ophthalmol Sci · December 2023 PURPOSE: To quantify rate of change of retinal microvascular and choroidal structural parameters in subjects with Parkinson's disease (PD) compared with controls using OCT and OCT angiography (OCTA). DESIGN: Prospective longitudinal study. PARTICIPANTS: Se ... Full text Link to item Cite

Longitudinal Assessment of the Choroidal Vascularity Index in Eyes with Branch Retinal Vein Occlusion-Associated Cystoid Macular Edema.

Journal Article Ophthalmol Ther · August 2023 INTRODUCTION: Cystoid macular edema (CME) is the most common cause of central vision loss in eyes with branch retinal vein occlusion (BRVO eyes). In recent literature, choroidal vascularity index (CVI) has been proposed to be an enhanced depth imaging opti ... Full text Link to item Cite

Pregnant individuals' information needs and intention to vaccinate their children with routine and COVID-19 vaccines: Findings from a cross-sectional survey.

Journal Article Int J Gynaecol Obstet · July 2023 OBJECTIVE: The current study assessed pregnant individuals' intention to accept routine and COVID-19 vaccines for their baby after birth, and to identify key demographic (e.g., age) and nondemographic characteristics (e.g., prior birth) associated with vac ... Full text Link to item Cite

Intrasession Repeatability of OCT Angiography Parameters in Neurodegenerative Disease.

Journal Article Ophthalmol Sci · June 2023 PURPOSE: To assess the intrasession repeatability of macular OCT angiography (OCTA) parameters in Alzheimer's disease (AD), mild cognitive impairment (MCI), Parkinson's disease (PD), and normal cognition (NC). DESIGN: Cross sectional study. SUBJECTS: Patie ... Full text Open Access Link to item Cite

The effect of sex on retinopathy of prematurity severity among premature mixed-sex multiple gestation infants.

Journal Article J AAPOS · June 2023 This retrospective study of 68 premature infants examined whether there was a difference between male and female mixed-sex multiple gestation infants with regard to stage of retinopathy of prematurity (ROP) developed or need for ROP treatment. We found tha ... Full text Link to item Cite

Systematic analysis of levels of evidence supporting American Academy of Ophthalmology Preferred Practice Pattern guidelines, 2012-2021.

Journal Article BMC Ophthalmol · March 31, 2023 BACKGROUND: Despite the increased emphasis on evidence-based medicine, the current state of evidence behind ophthalmology clinical practice guidelines is unknown. The purpose of this systematic analysis was to understand the levels of evidence (LOE) suppor ... Full text Link to item Cite

Glaucoma Fellows-in-Training Recent Surgery Trends.

Journal Article Ophthalmol Glaucoma · 2023 PURPOSE: The volume of microinvasive glaucoma surgery (MIGS) has increased dramatically in recent years, from 31 059 in 2013 to 69 420 in 2018. We investigated the impact of this trend on trainees by determining the proportion of glaucoma surgeries perform ... Full text Link to item Cite

Quantitative comparison of blood vessel changes after treatment of retinopathy of prematurity with laser versus bevacizumab.

Journal Article J AAPOS · December 2022 Current therapies for treatment-indicated (type 1) retinopathy of prematurity mainly consist of laser photocoagulation and intravitreal anti-vascular endothelial growth factor (eg, bevacizumab) injection. The first visible signs of acute-phase regression a ... Full text Link to item Cite

Continuous Hypoxia Reduces Retinal Ganglion Cell Degeneration in a Mouse Model of Mitochondrial Optic Neuropathy.

Journal Article Invest Ophthalmol Vis Sci · December 1, 2022 PURPOSE: To test whether continuous hypoxia is neuroprotective to retinal ganglion cells (RGCs) in a mouse model of mitochondrial optic neuropathy. METHODS: RGC degeneration was assessed in genetically modified mice in which the floxed gene for the complex ... Full text Link to item Cite

Outcomes of inferonasal glaucoma drainage device surgery in the management of childhood glaucoma.

Journal Article J AAPOS · October 2022 PURPOSE: To evaluate indications and postoperative outcomes of inferonasal Ahmed and Baerveldt glaucoma drainage devices (GDDs) in pediatric glaucoma. METHODS: This retrospective study included patients ≤18 years of age at inferonasal GDD placement, from J ... Full text Link to item Cite

Predominantly Persistent Intraretinal Fluid in the Comparison of Age-related Macular Degeneration Treatments Trials.

Journal Article Ophthalmol Retina · September 2022 PURPOSE: To describe predominantly persistent intraretinal fluid (PP-IRF) and its association with visual acuity (VA) and retinal anatomic findings at long-term follow-up in eyes treated with pro re nata (PRN) ranibizumab or bevacizumab for neovascular age ... Full text Link to item Cite

Longitudinal Evaluation of Visual Function Impairments in Early and Intermediate Age-Related Macular Degeneration Patients.

Journal Article Ophthalmol Sci · September 2022 PURPOSE: To evaluate visual function (VF) changes in early and intermediate age-related macular degeneration (eAMD and iAMD) over 24 months. DESIGN: Prospective, observational natural history study. PARTICIPANTS: Participants were enrolled at the Duke Eye ... Full text Link to item Cite

Longitudinal Analysis of the Retina and Choroid in Cognitively Normal Individuals at Higher Genetic Risk of Alzheimer Disease.

Journal Article Ophthalmol Retina · July 2022 PURPOSE: To assess the baseline differences and longitudinal rate of change in retinal and choroidal imaging parameters between apolipoprotein ε4 (APOE ε4) carriers and noncarriers with normal cognition. DESIGN: Prospective study. SUBJECTS: Four hundred th ... Full text Link to item Cite

ASSESSMENT OF RETINAL MICROVASCULAR ALTERATIONS IN INDIVIDUALS WITH AMNESTIC AND NONAMNESTIC MILD COGNITIVE IMPAIRMENT USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

Journal Article Retina · July 1, 2022 PURPOSE: To assess retinal microvascular alterations in individuals with amnestic mild cognitive impairment (MCI) and nonamnestic MCI. METHODS: One hundred twelve eyes of 59 amnestic MCI participants, 32 eyes of 17 nonamnestic MCI participants, and 111 eye ... Full text Link to item Cite

Elevated Levels of Growth/Differentiation Factor-15 in the Aqueous Humor and Serum of Glaucoma Patients.

Journal Article J Clin Med · January 29, 2022 Dysregulated levels of growth/differentiation factor-15 (GDF15), a divergent member of the transforming growth factor-beta super family, have been found to be associated with the pathology of various diseases. In this study, we evaluated the levels of GDF1 ... Full text Link to item Cite

Preliminary Results of Uveal Melanoma Treated With Iodine-125 Plaques: Analysis of Disease Control and Visual Outcomes With 63 Gy to the Target Volume.

Journal Article Adv Radiat Oncol · 2022 PURPOSE: Our purpose was to review the preliminary outcomes of patients with uveal melanoma treated with iodine-125 plaques using a novel treatment planning approach. METHODS AND MATERIALS: This was a single institution, retrospective review of patients tr ... Full text Link to item Cite

Repeatability of Peripapillary OCT Angiography in Neurodegenerative Disease.

Journal Article Ophthalmol Sci · December 2021 PURPOSE: To assess the repeatability of peripapillary OCT angiography (OCTA) in those with Alzheimer disease (AD), mild cognitive impairment (MCI), Parkinson disease (PD), or normal cognition. DESIGN: Cross-sectional. PARTICIPANTS: Patients with a clinical ... Full text Open Access Link to item Cite

Photographic assessment of eyelid position using a simple measurement tool paired with cell phone photography in a pediatric population.

Journal Article J AAPOS · October 2021 PURPOSE: This proof-of-concept study evaluates the ability to assess eyelid measurements and the reproducibility of eyelid measurements using a simple measurement tool paired with digital cell phone photography in children. METHODS: Seventy consecutive pat ... Full text Link to item Cite

Prophylactic laser versus continued surveillance after initial bevacizumab treatment for retinopathy of prematurity.

Journal Article J AAPOS · June 2021 Guidelines on managing infants after initial anti-vascular endothelial growth factor (VEGF) treatment (eg, bevacizumab) for retinopathy of prematurity (ROP) are limited. We found that following initial bevacizumab treatment for ROP, prophylactically laseri ... Full text Link to item Cite

Assessing the Retinal Microvasculature in Individuals With Early and Late-Onset Alzheimer's Disease.

Journal Article Ophthalmic Surg Lasers Imaging Retina · June 2021 BACKGROUND AND OBJECTIVE: To evaluate retinal microvascular changes in early and late-onset Alzheimer's disease (AD). PATIENTS AND METHODS: Eighty-six eyes of 50 late-onset AD participants, 27 eyes of 15 early onset AD participants, and 111 eyes of 57 cogn ... Full text Link to item Cite

Local Anatomic Precursors to New-Onset Geographic Atrophy in Age-Related Macular Degeneration as Defined on OCT.

Journal Article Ophthalmol Retina · May 2021 PURPOSE: In macula-wide analyses, spectral-domain (SD) optical coherence tomography (OCT) features including drusen volume, hyperreflective foci, and OCT-reflective drusen substructures independently predict geographic atrophy (GA) onset secondary to age-r ... Full text Link to item Cite

Effect of ICD-9 to ICD-10 Transition on Accuracy of Codes for Stage of Diabetic Retinopathy and Related Complications: Results from the CODER Study.

Journal Article Ophthalmol Retina · April 2021 PURPOSE: When the International Classification of Diseases 9th Revision (ICD-9) transitioned to the International Classification of Diseases 10th Revision (ICD-10), there was a marked increase in the complexity of International Classification of Diseases ( ... Full text Link to item Cite

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Journal Article Retina · March 1, 2021 Full text Link to item Cite

Quantitatively comparing weekly changes in retinal vascular characteristics of eyes eventually treated versus not treated for retinopathy of prematurity.

Journal Article J AAPOS · February 2021 PURPOSE: To quantitatively compare retinal vascular characteristics over time in eyes eventually treated versus not treated for retinopathy of prematurity (ROP), using ROPtool analysis of narrow-field retinal images. METHODS: This longitudinal study used p ... Full text Link to item Cite

Teleophthalmology: Evaluation of Phone-based Visual Acuity in a Pediatric Population.

Journal Article Am J Ophthalmol · January 2021 PURPOSE: With the recent rise of teleophthalmology due to coronavirus disease, health care needs accurate and reliable methods of checking visual acuity remotely. The visual acuity as measured by the GoCheck Kids application was compared with that of the A ... Full text Link to item Cite

Matrix metalloproteinase 9 positivity predicts long term decreased tear production.

Journal Article Ocul Surf · January 2021 PURPOSE: To investigate long-term correlations between Matrix Metalloproteinase-9 (MMP-9) testing and dry eye (DE) parameters. Additionally, to evaluate variability in MMP-9 results over time and with anti-inflammatory treatment. METHODS: Retrospective coh ... Full text Link to item Cite

A Pilot Study of Medical Misinformation Perceptions and Training Among Practitioners in North Carolina (USA).

Journal Article Inquiry · 2021 Medical misinformation (MM) is a problem for both medical practitioners and patients in the 21st century. Medical practitioners have anecdotally reported encounters with patient-held misinformation, but to date we lack evidence that quantifies this phenome ... Full text Link to item Cite

Barriers to the uptake of cervical cancer services and attitudes towards adopting new interventions in Peru.

Journal Article Prev Med Rep · December 2020 Cervical cancer mortality is high among Peruvian women of reproductive age. Understanding barriers and facilitators of cervical cancer screening and treatment could facilitate development of contextually-relevant interventions to reduce cervical cancer inc ... Full text Link to item Cite

Association of meibomian gland architecture and body mass index in a pediatric population.

Journal Article Ocul Surf · October 2020 PURPOSE: To determine if meibomian gland architecture in a pediatric population is impacted by body mass index (BMI). METHODS: Prospective evaluation of 175 eyes of 175 pediatric patients from two clinics. Demographic and clinical information were reviewed ... Full text Link to item Cite

Morphological characteristics of early- versus late-onset macular edema in preterm infants.

Journal Article J AAPOS · October 2020 Macular images of infants with early-onset edema (occurring at or before 33 weeks' postmenstrual age [PMA]) and infants with late-onset edema (at or after 36 weeks' PMA) were compared. At first appearance, early-onset edema has a more severe morphology, wi ... Full text Link to item Cite

Differences in Presentation and Outcomes in Males and Females With Branch Retinal Vein Occlusion.

Journal Article Ophthalmic Surg Lasers Imaging Retina · October 1, 2020 BACKGROUND AND OBJECTIVE: To investigate the effect of patient sex on presentation and outcomes of branch retinal vein occlusion (BRVO). PATIENTS AND METHODS: Retrospective chart review cohort study of 188 eyes with BRVO and cystoid macular edema (CME); 81 ... Full text Link to item Cite

Assessment of Visual and Retinal Function Following In Vivo Genipin-Induced Scleral Crosslinking.

Journal Article Transl Vis Sci Technol · September 2020 PURPOSE: Genipin has been proposed as a possible neuroprotective therapy in myopia and glaucoma. Here, we aim to determine the effects of prolonged genipin-induced scleral stiffening on visual function. METHODS: Eyes from Brown Norway rats were treated in ... Full text Link to item Cite

CORRELATION OF SUBRETINAL HYPERREFLECTIVE MATERIAL MORPHOLOGY AND VISUAL ACUITY IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.

Journal Article Retina · May 2020 PURPOSE: To evaluate the association of subretinal hyperreflective material (SHRM) morphological features with visual acuity in eyes with neovascular age-related macular degeneration. METHODS: Retrospective analysis of treatment-naïve patients with neovasc ... Full text Link to item Cite

Sex Differences in Presentation, Treatment Patterns, and Clinical Outcomes in Central Retinal Vein Occlusion.

Journal Article Ophthalmic Surg Lasers Imaging Retina · May 1, 2020 BACKGROUND AND OBJECTIVE: To evaluate the impact of sex differences on the presenting features, treatment patterns, and clinical outcomes in patients with central retinal vein occlusions (CRVO). PATIENTS AND METHODS: This retrospective, longitudinal cohort ... Full text Link to item Cite

Multi-center analysis of intraocular biopsy technique and outcomes for uveal melanoma: Ocular Oncology Study Consortium report 4.

Journal Article Graefes Arch Clin Exp Ophthalmol · February 2020 PURPOSE: To investigate the relationship between surgical approach for intraocular tumor biopsy of uveal melanoma and tumor morphologic features such as size and intraocular location and the effect of these variables on diagnostic yield and biopsy outcome. ... Full text Link to item Cite

CORRELATION OF GENE EXPRESSION PROFILE STATUS AND AMERICAN JOINT COMMISSION ON CANCER STAGE IN UVEAL MELANOMA.

Journal Article Retina · February 2020 PURPOSE: To study the relationship between gene expression profile (GEP) subclass and American Joint Committee on Cancer (AJCC) stage in patients with uveal melanoma (UM). METHODS: A retrospective, multicenter study was undertaken with patients entered fro ... Full text Link to item Cite

Co-Prevalence of Alzheimer's Disease and Age-Related Macular Degeneration Established by Histopathologic Diagnosis.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Previous epidemiologic studies have suggested an association between AMD and AD, and several therapeutic agents are being developed based on this principle. However, prior studies have provided conflicting results due in part to their reliance ... Full text Link to item Cite

Impact of Preoperative Video Education for Cataract Surgery on Patient Learning Outcomes.

Journal Article Clin Ophthalmol · 2020 PURPOSE: To assess the effect of an educational video on 1) patient knowledge about cataract surgery, 2) patient perception of preoperative assessment visit quality, 3) face-to-face time with the surgeon, and 4) choices regarding premium intraocular lenses ... Full text Link to item Cite

Assessment of retinal microvasculature in supine vs upright positioning using OCT-Angiography

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · 2020 Cite

Treatment Patterns and Clinical Outcomes for Central Retinal Vein Occlusion in the Antivascular Endothelial Growth Factor Era.

Journal Article J Vitreoretin Dis · 2020 PURPOSE: This article describes treatment patterns and visual outcomes for central retinal vein occlusion (CRVO) in the antivascular endothelial growth factor (anti-VEGF) era. METHODS: A retrospective cohort study of eyes diagnosed with CRVO between 2009 a ... Full text Link to item Cite

Assessment of Macular Microvasculature in Healthy Eyes of Infants and Children Using OCT Angiography.

Journal Article Ophthalmology · December 2019 PURPOSE: To assess macular vasculature in healthy infants and children using OCT angiography (OCTA). DESIGN: Prospective cross-sectional study. PARTICIPANTS: One hundred thirty-five normal maculae of 89 healthy infants and children (mean age, 8.5±5.3 years ... Full text Open Access Link to item Cite

Visual Acuity Assessment and Vision Screening Using a Novel Smartphone Application.

Journal Article J Pediatr · October 2019 OBJECTIVES: To evaluate a smartphone-based application's (Peek Acuity) ability to assess visual acuity and screen for ocular conditions in children, we compared visual acuity assessment between Peek Acuity and the pediatric ophthalmology examination and ev ... Full text Link to item Cite

Longitudinal Study of Visual Function in Dry Age-Related Macular Degeneration at 12 Months.

Journal Article Ophthalmol Retina · August 2019 PURPOSE: To report the 1-year progression of visual impairment on psychophysical tests of visual function in patients with early and intermediate age-related macular degeneration (AMD). DESIGN: Prospective, observational study. PARTICIPANTS: Patients with ... Full text Link to item Cite

Monocyte-related biomarkers of intermediate age-related macular degeneration

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · July 1, 2019 Link to item Cite

RELATIONSHIP OF CLINICAL FEATURES AND BASELINE TUMOR SIZE WITH GENE EXPRESSION PROFILE STATUS IN UVEAL MELANOMA: A Multi-institutional Study.

Journal Article Retina · June 2019 PURPOSE: To study the relationship between gene expression profile subclass and clinical features in a multicenter cohort of patients with uveal melanoma. METHODS: A retrospective, multicenter study was undertaken with patients entered from nine major ocul ... Full text Link to item Cite

IDENTIFICATION OF POSTERIOR SEGMENT PATHOLOGY WITH EN FACE RETINAL IMAGING USING MULTICOLOR CONFOCAL SCANNING LASER OPHTHALMOSCOPY.

Journal Article Retina · May 2019 PURPOSE: To assess posterior segment findings on multicolor confocal scanning laser ophthalmoscopy by correlation with spectral domain optical coherence tomography (SD-OCT) and to quantify agreement between these imaging modalities. METHODS: Retrospective ... Full text Link to item Cite

PERIVASCULAR THICKENING ON OPTICAL COHERENCE TOMOGRAPHY AS A MARKER OF INFLAMMATION IN BIRDSHOT RETINOCHOROIDITIS.

Journal Article Retina · May 2019 PURPOSE: In this study, we hypothesized that thickening along the major arcade vessels is a noninvasive marker of inflammation in eyes with birdshot retinochoroiditis (BRC). METHODS: In this single-center retrospective study, patients with BRC were identif ... Full text Link to item Cite

CO2 Laser Lash Tilt Technique for the Treatment of Mild to Moderate Lash Ptosis and Augmentation of Upper Eyelid Blepharoplasty Results.

Journal Article Ophthalmic Plast Reconstr Surg · 2019 PURPOSE: To assess the safety, efficacy, and patient satisfaction of a newly described technique for the treatment of mild to moderate lash ptosis performed as augmentation to upper eyelid blepharoplasty. METHODS: Patient medical records for 27 consecutive ... Full text Link to item Cite

Comorbidity of age-related macular degeneration with Alzheimer's disease: A histopathologic case-control study.

Journal Article PLoS One · 2019 INTRODUCTION: Previous studies evaluating the association between clinically diagnosed Alzheimer's disease (AD) and age-related macular degeneration (AMD) have generated conflicting results. This study is the first to assess whether AMD prevalence is highe ... Full text Link to item Cite

Understanding the variability of handheld spectral-domain optical coherence tomography measurements in supine infants.

Journal Article PLoS One · 2019 PURPOSE: Central foveal thickness (CFT) measurements from optical coherence tomography (OCT) scans provide a precise measure of severity of pathologic changes in the fovea, progress of disease and response to treatment. Although these measures are addition ... Full text Link to item Cite

Gray Optic Disc Crescent: Evaluation of Anatomic Correlate by Spectral-Domain OCT.

Journal Article Ophthalmol Glaucoma · 2019 PURPOSE: To test the hypothesis that the anatomic correlate of the gray optic disc crescent is pigmentation of externally oblique border tissue of Elschnig. DESIGN: Retrospective study. PARTICIPANTS: African-American adult men with or without clinically ap ... Full text Link to item Cite

Characterization of Corneal Donor Tissue Lesions by Anterior Segment Optical Coherence Tomography Compared With Eye Bank Technician Slit-Lamp Examination.

Journal Article Cornea · October 2018 PURPOSE: To compare anterior segment spectral-domain optical coherence tomography (OCT) with eye bank technician slit-lamp examination (SLE) in characterizing lesions in donor corneas. METHODS: Twenty-nine donor corneas identified by eye bank technicians t ... Full text Link to item Cite

The role of cystoid macular edema as a marker in the progression of non-paraneoplastic autoimmune retinopathy.

Journal Article Graefes Arch Clin Exp Ophthalmol · October 2018 PURPOSE: To determine the relationship between cystoid macular edema (CME) and disease severity and progression in non-paraneoplastic autoimmune retinopathy (npAIR). METHODS: A retrospective study was conducted on patients seen between 2008 and 2016 with n ... Full text Link to item Cite

Outcomes of Thermal Pulsation Treatment for Dry Eye Syndrome in Patients With Sjogren Disease.

Journal Article Cornea · September 2018 PURPOSE: To evaluate the clinical outcomes of thermal pulsation treatment in patients with meibomian gland dysfunction (MGD) and dry eye secondary to Sjogren disease. METHODS: Twenty-four eyes from 13 patients with previously diagnosed Sjogren disease who ... Full text Link to item Cite

Non-contact retinal imaging compared to indirect ophthalmoscopy for retinopathy of prematurity screening: infant safety profile.

Journal Article J Perinatol · September 2018 OBJECTIVE: Most retinopathy of prematurity screening involves an ophthalmologist performing indirect ophthalmoscopy, which can be stressful to infants. The purpose of this study is to evaluate the safety profile (using cardiopulmonary events as an indicato ... Full text Link to item Cite

Evaluating a Portable, Noncontact Fundus Camera for Retinopathy of Prematurity Screening by Nonophthalmologist Health Care Workers.

Journal Article Ophthalmol Retina · August 2018 PURPOSE: To evaluate (1) the feasibility of non-ophthalmologist healthcare workers (HCWs) to obtain images of sufficient quality for retinopathy of prematurity (ROP) screening using a FDA-approved portable, non-contact, narrow-field fundus camera (i.e., Pi ... Full text Link to item Cite

Macular Features on Spectral-Domain Optical Coherence Tomography Imaging Associated With Visual Acuity in Coats' Disease.

Journal Article Invest Ophthalmol Vis Sci · June 1, 2018 PURPOSE: To investigate the association between macular features on spectral-domain optical coherence tomography (SD-OCT) and visual acuity (VA) in Coats' disease. METHODS: Thirty-nine eyes (39 patients) with SD-OCT from January 1, 2008 to December 31, 201 ... Full text Link to item Cite

Visual Function Metrics in Early and Intermediate Dry Age-related Macular Degeneration for Use as Clinical Trial Endpoints.

Journal Article Am J Ophthalmol · May 2018 PURPOSE: To evaluate and quantify visual function metrics to be used as endpoints of age-related macular degeneration (AMD) stages and visual acuity (VA) loss in patients with early and intermediate AMD. DESIGN: Cross-sectional analysis of baseline data fr ... Full text Link to item Cite

Volumetric Measurement of Subretinal Blebs Using Microscope-Integrated Optical Coherence Tomography.

Journal Article Transl Vis Sci Technol · April 2018 PURPOSE: We advance studies of subretinal treatments by developing a microscope-integrated optical coherence tomography (MIOCT) image-based method for measuring the volume of therapeutics delivered into the subretinal space. METHODS: A MIOCT image-based vo ... Full text Link to item Cite

Efficacy and Safety of Low-Dose Iodine Plaque Brachytherapy for Juxtapapillary Choroidal Melanoma.

Journal Article Am J Ophthalmol · February 2018 PURPOSE: To evaluate low- vs high-dose plaque brachytherapy for juxtapapillary choroidal melanoma. DESIGN: Retrospective interventional case series. METHODS: Setting: Single institution. STUDY POPULATION: Forty-seven patients with juxtapapillary choroidal ... Full text Link to item Cite

Association of Low Luminance Questionnaire With Objective Functional Measures in Early and Intermediate Age-Related Macular Degeneration.

Journal Article Invest Ophthalmol Vis Sci · January 1, 2018 PURPOSE: To determine whether Low Luminance Questionnaire (LLQ) scores are associated with objective measures of visual function in early and intermediate age-related macular degeneration (AMD). METHODS: Cross-sectional study of subjects with early AMD Age ... Full text Link to item Cite

Evaluation of inner retinal layers as biomarkers in mild cognitive impairment to moderate Alzheimer's disease.

Journal Article PLoS One · 2018 Inner retina in Alzheimer's Disease (AD) may experience neuroinflammation resulting in atrophy. The objective of our study was to determine whether retinal GCIPL (ganglion cell-inner plexiform layer) or nerve fiber layer (NFL) thickness may serve as noninv ... Full text Link to item Cite

Identifying risk factors for blindness from primary open-angle glaucoma by race: a case-control study.

Journal Article Clin Ophthalmol · 2018 PURPOSE: To examine the factors associated with blindness from primary open-angle glaucoma (POAG) among black and white patients at our institution. PATIENTS AND METHODS: For this retrospective, case-control study, patients legally blind from POAG ("cases" ... Full text Open Access Link to item Cite

The Relationship of Vogt-Koyanagi-Harada Syndrome to Ocular Hypertension and Glaucoma.

Journal Article Ocul Immunol Inflamm · December 2017 PURPOSE: Vogt-Koyanagi-Harada (VKH) syndrome is a systemic inflammatory autoimmune disease with associated ophthalmic pathology. Glaucoma has been reported in patients with VKH. The purpose of this report is to examine the frequency and types of glaucoma a ... Full text Link to item Cite

Clinical Implications of Direct Immunofluorescence Findings in Patients With Ocular Mucous Membrane Pemphigoid.

Journal Article Am J Ophthalmol · November 2017 PURPOSE: To examine the clinical implications of positive or negative direct immunofluorescence biopsies (DIF) in patients with clinically typical ocular mucous membrane pemphigoid (MMP). DESIGN: Retrospective cohort study. METHODS: The study population wa ... Full text Link to item Cite

Association between Tumor Regression Rate and Gene Expression Profile after Iodine 125 Plaque Radiotherapy for Uveal Melanoma.

Journal Article Ophthalmology · October 2017 PURPOSE: Gene expression profile (GEP) testing segregates uveal melanoma (UM) into 2 main prognostic classes. It is unknown if a greater tumor regression response after iodine 125 (I125) brachytherapy correlates with class 2 GEP status. The purpose of this ... Full text Link to item Cite

Characterization of Artifacts Associated With Multicolor Confocal Scanning Laser Ophthalmoscopy.

Journal Article Ophthalmic Surg Lasers Imaging Retina · October 1, 2017 BACKGROUND AND OBJECTIVE: To characterize the appearance of three types of artifacts observed on multicolor confocal scanning laser ophthalmoscopy (cSLO). PATIENTS AND METHODS: Retrospective review of 159 eyes of 96 consecutive patients from the Duke Eye C ... Full text Link to item Cite

Comparison of Visual Outcomes in Coats' Disease: A 20-Year Experience.

Journal Article Ophthalmology · September 2017 PURPOSE: To report differences in visual acuities among patients with Coats' disease who sought treatment at a tertiary care university-based practice. DESIGN: Single-center retrospective cohort study. PARTICIPANTS: Patients with Coats' disease diagnosed c ... Full text Link to item Cite

Completeness of facial self-application of sunscreen in cosmetic surgery patients.

Journal Article Cutis · June 2017 Previous studies have demonstrated incomplete sunscreen self-application to various facial regions in cosmetic surgery patients, but there is no scientific research on the completeness of facial and periocular sunscreen self-application using ultraviolet ( ... Link to item Cite

Completeness of facial self-application of sunscreen in cosmetic surgery patients

Journal Article Cutis · June 1, 2017 Previous studies have demonstrated incomplete sunscreen self-application to various facial regions in cosmetic surgery patients, but there is no scientific research on the completeness of facial and periocular sunscreen self-application using ultraviolet ( ... Cite

Comparison of Anterior Segment Optical Coherence Tomography Bleb Grading, Moorfields Bleb Grading System, and Intraocular Pressure After Trabeculectomy.

Journal Article J Glaucoma · May 2017 PURPOSE: To compare a novel anterior segment optical coherence tomography (AS-OCT) bleb grading system with a clinical bleb grading system and both with intraocular pressure (IOP) following trabeculectomy surgery. MATERIALS AND METHODS: A novel AS-OCT grad ... Full text Link to item Cite

Retrospective analysis of translaminar, demographic, and physiologic parameters in relation to papilledema severity.

Journal Article Can J Ophthalmol · February 2017 OBJECTIVE: Some case reports suggest that the translaminar pressure difference is important in cases of papilledema. The purpose of this study was to determine ocular, physiologic, and demographic factors associated with papilledema severity. DESIGN: Retro ... Full text Link to item Cite

Use of a Noise Optimized Monoenergetic Algorithm for Patient-Size Independent Selection of an Optimal Energy Level During Dual-Energy CT of the Pancreas.

Journal Article J Comput Assist Tomogr · January 2017 PURPOSE: To investigate the impact of a second-generation noise-optimized monoenergetic algorithm on selection of the optimal energy level, image quality, and effect of patient body habitus for dual-energy multidetector computed tomography of the pancreas. ... Full text Link to item Cite

Cytokine biomarkers in tear film for primary open-angle glaucoma.

Journal Article Clin Ophthalmol · 2017 PURPOSE: To determine the utility of tear film cytokines as biomarkers for early primary open-angle glaucoma (POAG). METHODS: Patients without POAG and eye drop-naïve patients with newly diagnosed POAG were recruited from an academic hospital-based glaucom ... Full text Open Access Link to item Cite

Effect of thermal pulsation treatment on tear film parameters in dry eye disease patients.

Journal Article Clin Ophthalmol · 2017 PURPOSE: The goal of this study was to evaluate the effect of thermal pulsation treatment on tear film parameters, specifically osmolarity and matrix metalloproteinase-9 (MMP-9), in patients with meibomian gland dysfunction (MGD) and dry eye disease (DED). ... Full text Link to item Cite

Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration.

Journal Article Ophthalmology · December 2016 PURPOSE: Structural and compositional heterogeneity within drusen comprising lipids, carbohydrates, and proteins have been previously described. We sought to detect and define phenotypic patterns of drusen heterogeneity in the form of optical coherence tom ... Full text Link to item Cite

Bariatric Radioembolization: A Pilot Study on Technical Feasibility and Safety in a Porcine Model.

Journal Article J Vasc Interv Radiol · October 2016 PURPOSE: To evaluate feasibility of left gastric artery (LGA) yttrium-90 ((90)Y) radioembolization as potential treatment for obesity in a porcine model. MATERIALS AND METHODS: This study included 8 young female pigs (12-13 weeks, 21.8-28.1 kg). Six animal ... Full text Link to item Cite

Analysis of Cerebrospinal Fluid Pressure Estimation Using Formulae Derived From Clinical Data.

Journal Article Invest Ophthalmol Vis Sci · October 1, 2016 PURPOSE: To evaluate a frequently used regression model and a new, modified regression model to estimate cerebrospinal fluid pressure (CSFP). METHODS: Datasets from the Beijing iCOP study from Tongren Hospital, Beijing, China, and the Mayo Clinic, Rocheste ... Full text Link to item Cite

Injectable Fluocinolone Acetonide Long-Acting Implant for Noninfectious Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Two-Year Results.

Journal Article Ophthalmology · September 2016 PURPOSE: To determine the effect of an injectable fluocinolone acetonide implant (FAi) in eyes with noninfectious intermediate uveitis, posterior uveitis, or panuveitis. DESIGN: Noncomparative, interventional, dose-randomized, dose-masked, prospective, ind ... Full text Link to item Cite

Retinal Biomarkers of Alzheimer's Disease

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · September 1, 2016 Link to item Cite

Outcomes of intense pulsed light therapy for treatment of evaporative dry eye disease.

Journal Article Can J Ophthalmol · August 2016 OBJECTIVE: To determine the clinical outcomes of intense pulsed light (IPL) therapy for the treatment of evaporative dry eye disease (DED). DESIGN: Multicentre cohort study. PARTICIPANTS: Patients with a diagnosis of meibomian gland dysfunction (MGD) and d ... Full text Link to item Cite

Rate of intraoperative complications during cataract surgery following intravitreal injections.

Journal Article Eye (Lond) · August 2016 PurposeTo investigate the effect of prior intravitreal injections on intraoperative and postoperative complication rates associated with cataract surgery.MethodsA retrospective cohort analysis reviewed 10 105 cataract surgery procedures performed by experi ... Full text Link to item Cite

Alvimopan Provides Additional Improvement in Outcomes and Cost Savings in Enhanced Recovery Colorectal Surgery.

Conference Ann Surg · July 2016 OBJECTIVE: To examine the impact of alvimopan on outcomes and costs in a rigorous enhanced recovery colorectal surgery protocol. BACKGROUND: Postoperative ileus remains a major source of morbidity and costs in colorectal surgery. Alvimopan has been shown t ... Full text Link to item Cite

Impact of Microscope-Integrated OCT on Ophthalmology Resident Performance of Anterior Segment Surgical Maneuvers in Model Eyes.

Journal Article Invest Ophthalmol Vis Sci · July 1, 2016 PURPOSE: The integration of swept-source optical coherence tomography (SS-OCT) into the operating microscope enables real-time, tissue-level three-dimensional (3D) imaging to aid in ophthalmic microsurgery. In this prospective randomized controlled study, ... Full text Link to item Cite

Effect of a Noise-Optimized Second-Generation Monoenergetic Algorithm on Image Noise and Conspicuity of Hypervascular Liver Tumors: An In Vitro and In Vivo Study.

Journal Article AJR Am J Roentgenol · June 2016 OBJECTIVE: The purpose of this study is to investigate whether the reduction in noise using a second-generation monoenergetic algorithm can improve the conspicuity of hypervascular liver tumors on dual-energy CT (DECT) images of the liver. MATERIALS AND ME ... Full text Link to item Cite

VISUAL FUNCTION MEASURES IN EARLY AND INTERMEDIATE AGE-RELATED MACULAR DEGENERATION.

Journal Article Retina · May 2016 PURPOSE: The objectives of this study were to evaluate 1) the feasibility of performing computerized tests of low luminance visual acuity (LLVA), cone-specific contrast (Cone Contrast Test [CCT]), contrast sensitivity, and microperimetry and 2) the test-re ... Full text Link to item Cite

SMALL-GAUGE VALVED VERSUS NONVALVED CANNULA PARS PLANA VITRECTOMY FOR RETINAL DETACHMENT REPAIR.

Journal Article Retina · April 2016 PURPOSE: To compare functional and anatomical outcomes and complication rates between valved versus traditional nonvalved small-gauge cannula vitrectomy for retinal detachment repair. METHODS: Retrospective case series of 163 eyes undergoing small-gauge va ... Full text Link to item Cite

Virtual Monochromatic Images from Dual-Energy Multidetector CT: Variance in CT Numbers from the Same Lesion between Single-Source Projection-based and Dual-Source Image-based Implementations.

Journal Article Radiology · April 2016 PURPOSE: To determine the variance in virtual monochromatic computed tomography (CT) numbers from the same lesion, comparing the two clinically available dual-energy multidetector CT hardware implementations (single-source projection-based and dual-source ... Full text Link to item Cite

Ocular Biometrics of Myopic Eyes With Narrow Angles.

Journal Article J Glaucoma · February 2016 PURPOSE: The purpose of this study was to compare the ocular biometrics between myopic patients with and without narrow angles. METHODS: Patients with a stable myopic refraction (myopia worse than -1.00 D spherical equivalent) were prospectively recruited. ... Full text Link to item Cite

A Comparative Study of Rebound Tonometry With Tonopen and Goldmann Applanation Tonometry Following Vitreoretinal Surgery.

Journal Article Am J Ophthalmol · January 2016 PURPOSE: To investigate agreement in intraocular pressure (IOP) measurements among Icare rebound tonometry, Tonopen tonometry, and Goldmann applanation tonometry following vitreoretinal surgery. DESIGN: Reliability analysis of tonometers. METHODS: Fifty-ey ... Full text Link to item Cite

Reply.

Other Ophthalmology · January 2016 Full text Link to item Cite

An upright eyedrop bottle: accuracy, usage of excess drops, and contamination compared to a conventional bottle.

Journal Article Clin Ophthalmol · 2016 PURPOSE: This study tested the feasibility of using an upright eyedrop bottle (UEB), a device designed to assist patients with eyedrop placement without reclining their head. PATIENTS AND METHODS: Experienced eyedrop users were enrolled who answered "yes" ... Full text Link to item Cite

Valved versus nonvalved cannula small-gauge pars plana vitrectomy for repair of retinal detachments with Grade C proliferative vitreoretinopathy.

Journal Article Clin Ophthalmol · 2016 PURPOSE: Valved cannulas are a recent addition to small-gauge pars plana vitrectomy (PPV) and provide stable intraocular fluidics. The goal of this study was to compare outcomes and postoperative complication rates of valved vs nonvalved cannula small-gaug ... Full text Link to item Cite

Improved Surgical Success of Combined Glaucoma Tube Shunt and Retisert(®) Implantation in Uveitic Eyes: A Retrospective Study.

Journal Article Ophthalmol Ther · December 2015 INTRODUCTION: The purpose of this study was to determine whether the outcomes following placement of a fluocinolone acetonide implant (Retisert(®); Bausch & Lomb, Inc.) combined with an Ahmed™ glaucoma valve (New World Medical, Inc.) in eyes with uveitic g ... Full text Link to item Cite

Diagnostic Algorithm for Patients With Suspected Giant Cell Arteritis.

Journal Article J Neuroophthalmol · September 2015 BACKGROUND: To identify clinical and laboratory factors contributing to the diagnosis of giant cell arteritis (GCA) and develop a diagnostic algorithm for the evaluation of GCA. METHODS: Retrospective review of 213 consecutive cases of temporal artery biop ... Full text Link to item Cite

Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials.

Journal Article Ophthalmology · September 2015 PURPOSE: To evaluate the association of subretinal hyperreflective material (SHRM) with visual acuity (VA), geographic atrophy (GA), and scar in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). DESIGN: Prospective cohort study w ... Full text Link to item Cite

IDENTIFICATION OF FLUID ON OPTICAL COHERENCE TOMOGRAPHY BY TREATING OPHTHALMOLOGISTS VERSUS A READING CENTER IN THE COMPARISON OF AGE-RELATED MACULAR DEGENERATION TREATMENTS TRIALS.

Journal Article Retina · July 2015 PURPOSE: To examine treatment decisions by ophthalmologists versus reading center fluid identification from optical coherence tomography in Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). METHODS: Fluid in 6,210 optical coherence t ... Full text Link to item Cite

Relationship of central choroidal thickness with age-related macular degeneration status.

Journal Article Am J Ophthalmol · April 2015 PURPOSE: To compare choroidal thickness in patients with intermediate or advanced age-related macular degeneration (AMD) and control subjects using enhanced-depth imaging optical coherence tomography (EDI-OCT). DESIGN: Retrospective cross-sectional study o ... Full text Link to item Cite

Outcomes of eyes with lesions composed of >50% blood in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT).

Journal Article Ophthalmology · February 2015 OBJECTIVE: To compare baseline characteristics, treatment frequency, visual acuity (VA), and morphologic outcomes of eyes with >50% of the lesion composed of blood (B50 group) versus all other eyes (Other group) enrolled in the Comparison of Age-Related Ma ... Full text Link to item Cite

Stress and burnout in residents: impact of mindfulness-based resilience training.

Journal Article Adv Med Educ Pract · 2015 BACKGROUND AND OBJECTIVE: Stress and burnout impact resident physicians. This prospective study tests the hypothesis that a mindfulness-based resilience intervention would decrease stress and burnout in residents. METHODS: Resident physicians from the Depa ... Full text Open Access Link to item Cite

Glaucoma Blindness at a Tertiary Eye Care Center.

Journal Article N C Med J · 2015 BACKGROUND: Glaucoma is an important cause of irreversible blindness. This study describes the characteristics of a large, diverse group of glaucoma patients and evaluates associations between demographic and clinical characteristics and blindness. METHODS ... Full text Link to item Cite

Effect of Body Habitus on Radiation Dose During CT Fluoroscopy-Guided Spine Injections.

Journal Article Interv Neuroradiol · October 31, 2014 This study investigated the degree to which body habitus influences radiation dose during CT fluoroscopy (CTF)-guided lumbar epidural steroid injections (ESI). An anthropomorphic phantom containing metal oxide semiconductor field effect transistor (MOSFET) ... Full text Link to item Cite

Evaluation of optic nerve development in preterm and term infants using handheld spectral-domain optical coherence tomography.

Journal Article Ophthalmology · September 2014 PURPOSE: To evaluate effects of prematurity on early optic nerve (ON) development and the usefulness of ON parameters as indicators of central nervous system (CNS) development and pathology. DESIGN: Prospective, cross-sectional, longitudinal study. PARTICI ... Full text Link to item Cite

Vitamin D deficiency in neovascular versus nonneovascular age-related macular degeneration.

Journal Article Retina · September 2014 PURPOSE: To compare 25-hydroxyvitamin D (25OHD) levels in patients with neovascular age-related macular degeneration (NVAMD) with patients with nonneovascular age-related macular degeneration and control patients. METHODS: Medical records of all patients d ... Full text Link to item Cite

The effect of neoadjuvant radiation therapy on perioperative outcomes among patients undergoing resection of retroperitoneal sarcomas.

Journal Article Surg Oncol · September 2014 BACKGROUND: Neoadjuvant radiation therapy (RT) has several theoretical benefits in the treatment of retroperitoneal sarcoma (RPS), but concerns remain about treatment toxicity and perioperative morbidity. There are limited data regarding its effect on peri ... Full text Link to item Cite

Sustained visual acuity loss in the comparison of age-related macular degeneration treatments trials.

Journal Article JAMA Ophthalmol · August 2014 IMPORTANCE: Although anti-vascular endothelial growth factor treatment of neovascular age-related macular degeneration (AMD) results in improved vision overall, loss of substantial vision can occur. Understanding the processes that lead to loss of vision m ... Full text Link to item Cite

Sporadic visual acuity loss in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT).

Journal Article Am J Ophthalmol · July 2014 PURPOSE: To evaluate transient, large visual acuity (VA) decreases, termed sporadic vision loss, during anti-vascular endothelial growth factor treatment for neovascular age-related macular degeneration (AMD). DESIGN: Cohort within a randomized clinical tr ... Full text Link to item Cite

Risk factors for exposure of glaucoma drainage devices: a retrospective observational study.

Journal Article BMJ Open · May 2, 2014 OBJECTIVES: The purpose of this study was to identify risk factors for exposure of glaucoma drainage devices (GDD). SETTING: This retrospective, observational study was conducted in the eye clinic of an academic medical centre. PARTICIPANTS: Participants i ... Full text Link to item Cite

VEGFA and VEGFR2 gene polymorphisms and response to anti-vascular endothelial growth factor therapy: comparison of age-related macular degeneration treatments trials (CATT).

Journal Article JAMA Ophthalmol · May 2014 IMPORTANCE: Individual variation in response and duration of anti-vascular endothelial growth factor (VEGF) therapy is seen among patients with neovascular age-related macular degeneration. Identification of genetic markers that affect clinical response ma ... Full text Link to item Cite

An upright eye drop bottle

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

CSF Trends in Diseases Associated with Glaucoma

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

Eye Health Education: How Do Patients Want To Learn?

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2014 Link to item Cite

Vision-related quality of life in children with glaucoma.

Journal Article J AAPOS · February 2014 Although reporting vision-related quality of life (VRQoL) outcomes has become increasingly common in adult glaucoma studies, little is known about the influence of disease severity, medication burden, and surgical experience on the quality of life of child ... Full text Link to item Cite

Clinical practice guideline: acute otitis externa.

Journal Article Otolaryngol Head Neck Surg · February 2014 OBJECTIVE: This clinical practice guideline is an update and replacement for an earlier guideline published in 2006 by the American Academy of Otolaryngology-Head and Neck Surgery Foundation. This update provides evidence-based recommendations to manage ac ... Full text Link to item Cite

Patient education preferences in ophthalmic care.

Journal Article Patient Prefer Adherence · 2014 BACKGROUND: The learning preferences of ophthalmology patients were examined. METHODS: Results from a voluntary survey of ophthalmology patients were analyzed for education preferences and for correlation with race, age, and ophthalmic topic. RESULTS: To l ... Full text Open Access Link to item Cite

Real-time, computer-assisted quantification of plus disease in retinopathy of prematurity at the bedside.

Journal Article Ophthalmic Surg Lasers Imaging Retina · 2014 BACKGROUND AND OBJECTIVE: Plus disease is the primary indication for retinopathy of prematurity (ROP) treatment, but in borderline cases ophthalmologists may struggle to judge whether it is present. ROPtool is a semi-automated computer program that objecti ... Full text Link to item Cite

Pharmacokinetic interactions and safety evaluations of coadministered tafenoquine and chloroquine in healthy subjects.

Journal Article Br J Clin Pharmacol · December 2013 AIMS: The long-acting 8-aminoquinoline tafenoquine (TQ) coadministered with chloroquine (CQ) may radically cure Plasmodium vivax malaria. Coadministration therapy was evaluated for a pharmacokinetic interaction and for pharmacodynamic, safety and tolerabil ... Full text Link to item Cite

Reading Center Characterization of Central Retinal Vein Occlusion Using Optical Coherence Tomography During the COPERNICUS Trial.

Journal Article Transl Vis Sci Technol · November 2013 PURPOSE: To determine the impact of segmentation error correction and precision of standardized grading of time domain optical coherence tomography (OCT) scans obtained during an interventional study for macular edema secondary to central retinal vein occl ... Full text Link to item Cite

Effect of cornea donor graft thickness on the outcome of Descemet stripping automated endothelial keratoplasty surgery.

Journal Article Am J Ophthalmol · November 2013 PURPOSE: To determine whether Descemet stripping automated endothelial keratoplasty (DSAEK) donor cornea graft thickness impacts measurements of best spectacle-corrected visual acuity (BSCVA), refractive error and intraocular pressure (IOP). DESIGN: Retros ... Full text Link to item Cite

FDG-PET/CT characterization of adrenal nodules: diagnostic accuracy and interreader agreement using quantitative and qualitative methods.

Journal Article Acad Radiol · August 2013 PURPOSE: To determine interreader agreement and diagnostic accuracy across varying levels of reader experience using qualitative and quantitative methods of evaluating adrenal nodules using ((18)F)-fluorodeoxyglucose-positron emission tomography/computed t ... Full text Link to item Cite

Evidence-based medicine in otolaryngology Part 4: everyday probabilities--nonbinary diagnostic tests.

Journal Article Otolaryngol Head Neck Surg · August 2013 Many diagnostic tests have nonbinary results. Thus, this fourth installment of our series in evidence-based medicine in otolaryngology focuses on understanding diagnostic tests with more than 2 possible results. We begin with a brief review of the types of ... Full text Link to item Cite

Aflibercept-related sterile inflammation.

Journal Article Ophthalmology · May 2013 Full text Link to item Cite

Bariatric embolization for suppression of the hunger hormone ghrelin in a porcine model.

Journal Article Radiology · February 2013 PURPOSE: To prospectively test in a porcine model the hypothesis that bariatric embolization with commercially available calibrated microspheres can result in substantial suppression of systemic ghrelin levels and affect weight gain over an 8-week period. ... Full text Link to item Cite

Spinal meningeal diverticula in spontaneous intracranial hypotension: analysis of prevalence and myelographic appearance.

Journal Article AJNR Am J Neuroradiol · 2013 BACKGROUND AND PURPOSE: Spinal meningeal diverticula have been implicated in the pathogenesis of spontaneous intracranial hypotension and have been proposed as both diagnostic features of and therapeutic targets for the condition. We compared the prevalenc ... Full text Link to item Cite

Multiphase multi-detector row computed tomography in the setting of chronic liver disease and orthotopic liver transplantation: can a series be eliminated in order to reduce radiation dose?

Journal Article J Comput Assist Tomogr · 2013 OBJECTIVE: The objectives of this study were to explore utilization of multi-detector row computed tomography (MDCT) in screening for hepatocellular carcinoma (HCC) and to modify a liver CT protocol with a goal of dose reduction. METHODS: An electronic mai ... Full text Link to item Cite

Optical coherence tomography grading reproducibility during the Comparison of Age-related Macular Degeneration Treatments Trials.

Journal Article Ophthalmology · December 2012 OBJECTIVE: To report reading center reproducibility during grading of Stratus optical coherence tomography (OCT) (Carl Zeiss Meditec, Dublin, CA) images obtained during the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). DESIGN: Pr ... Full text Link to item Cite

Comparison of color fundus photographs and fundus autofluorescence images in measuring geographic atrophy area.

Journal Article Retina · October 2012 Featured Publication PURPOSE: To assess the agreement between color fundus photographs (CFP) and fundus autofluorescence (FAF) images when measuring geographic atrophy (GA) area and reproducibility of measurements between graders. Frequency and disagreement types were also det ... Full text Link to item Cite

Characterization of vitreoretinal interface disorders using OCT in the interventional phase 3 trials of ocriplasmin.

Journal Article Invest Ophthalmol Vis Sci · September 21, 2012 Featured Publication PURPOSE: We determined the reproducibility of a novel optical coherence tomography (OCT) protocol designed to evaluate formally vitreoretinal interface abnormalities on scans obtained during two phase 3 studies of intravitreal ocriplasmin to treat symptoma ... Full text Link to item Cite

Evidence-based medicine in otolaryngology, Part 3: everyday probabilities: diagnostic tests with binary results.

Journal Article Otolaryngol Head Neck Surg · August 2012 Recent studies have demonstrated that the majority of physicians cannot accurately determine the predictive values of diagnostic tests. Physicians must understand the predictive probabilities associated with diagnostic testing in order to convey accurate i ... Full text Link to item Cite

Effectiveness of cevimeline to improve oral health in patients with postradiation xerostomia.

Journal Article Head Neck · August 2012 BACKGROUND: We assessed the effectiveness of cevimeline 30 mg 3 times daily in patient-reported oral health (Oral Health Impact Profile [OHIP-49]) and quality of life (QOL) in patients with xerostomia. METHODS: In our investigator-initiated, multicenter, r ... Full text Link to item Cite

Increased Rates of Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK) Graft Failure and Dislocation in Glaucomatous Eyes with Aqueous Shunts.

Journal Article J Ophthalmic Vis Res · July 2012 PURPOSE: To investigate the rates of Descemet's stripping automated endothelial keratoplasty (DSAEK) graft dislocation and failure in glaucomatous eyes, including eyes with history of trabeculectomy and/or aqueous shunts. METHODS: A retrospective, case-con ... Link to item Cite

Analysis of corpus callosum diffusion tensor imaging parameters in infants.

Journal Article Neuroradiol J · July 2012 Radial diffusivity is a diffusion tensor imaging (DTI) metric that has received increased attention in recent studies as a parameter that may better reflect myelination than the more commonly-used fractional anisotropy (FA). This study compared rates of ra ... Full text Link to item Cite

Corneal biometry from volumetric SDOCT and comparison with existing clinical modalities.

Journal Article Biomed Opt Express · June 1, 2012 Featured Publication We present a comparison of corneal biometric values from dense volumetric spectral domain optical coherence tomography (SDOCT) scans to reference values in both phantoms and clinical subjects. We also present a new optically based "keratometric equivalent ... Full text Link to item Cite

Prevalence of sleep apnea in patients with keratoconus.

Journal Article Cornea · June 2012 Featured Publication PURPOSE: To determine the prevalence of obstructive sleep apnea (OSA) in patients with keratoconus and evaluate the risk of developing OSA in this patient population. METHODS: Three hundred sixty-two patients diagnosed with keratoconus by a single physicia ... Full text Link to item Cite

The influence of health literacy level on an educational intervention to improve glaucoma medication adherence.

Journal Article Patient Educ Couns · May 2012 Featured Publication OBJECTIVE: To test an educational intervention targeted to health literacy level with the goal of improving glaucoma medication adherence. METHODS: One hundred and twenty-seven veterans with glaucoma were randomized to glaucoma education or standard care. ... Full text Link to item Cite

Image inversion spectral-domain optical coherence tomography optimizes choroidal thickness and detail through improved contrast.

Journal Article Invest Ophthalmol Vis Sci · April 6, 2012 PURPOSE: This study was conducted to determine whether there were significant differences in choroidal thickness, contrast, outer choroidal vessel (OCV), and choroidal-scleral junction (CSJ) visualization in inverted versus upright spectral-domain optical ... Full text Link to item Cite

Body mass index has a linear relationship with cerebrospinal fluid pressure.

Journal Article Invest Ophthalmol Vis Sci · March 2012 PURPOSE: To examine the relationship between body mass index (BMI) and cerebrospinal fluid pressure (CSFP), as low BMI and low CSFP have recently been described as risk factors for primary open-angle glaucoma (POAG). METHODS: This was a retrospective revie ... Full text Link to item Cite

Trust in the provider and glaucoma-related blindness.

Journal Article ISRN Ophthalmol · 2012 Purpose. We hypothesized that lower trust in the physician is associated with worse visual outcomes in glaucoma. Methods. Subjects completed the Trust in Provider Scale (TPS) and performed visual field tests at least two years apart. The primary outcome wa ... Full text Link to item Cite

Clinical characteristics in 53 patients with cat scratch optic neuropathy.

Journal Article Ophthalmology · January 2012 OBJECTIVE: To describe the clinical manifestations and to identify risk factors associated with visual outcome in a large cohort of patients with cat scratch optic neuropathy (CSON). DESIGN: Multicenter, retrospective chart review. PARTICIPANTS: Fifty-thre ... Full text Link to item Cite

Prospective study of a fluocinolone acetonide implant for chronic macular edema from central retinal vein occlusion: thirty-six-month results.

Journal Article Ophthalmology · January 2012 Featured Publication PURPOSE: To assess long-term visual outcomes and adverse events from a fluocinolone acetonide (FA) sustained drug delivery implant in eyes with chronic macular edema from central retinal vein occlusion (CRVO). DESIGN: Prospective interventional case series ... Full text Link to item Cite

Subfoveal fluid in healthy full-term newborns observed by handheld spectral-domain optical coherence tomography.

Journal Article Am J Ophthalmol · January 2012 Featured Publication PURPOSE: To report retinal findings for healthy newborn infants imaged with handheld spectral-domain optical coherence tomography (SD OCT). DESIGN: Prospective, observational case series. METHODS: Thirty-nine full-term newborn infants underwent dilated ret ... Full text Link to item Cite

Cerebrospinal fluid pressure decreases with older age.

Journal Article PLoS One · 2012 PURPOSE: Clinical studies implicate low cerebrospinal fluid pressure (CSFP) or a high translaminar pressure difference in the pathogenesis of primary open angle glaucoma (POAG) and normal tension glaucoma (NTG). This study was performed to examine the effe ... Full text Link to item Cite

Dynamics of human foveal development after premature birth.

Journal Article Ophthalmology · December 2011 PURPOSE: To determine the dynamic morphologic development of the human fovea in vivo using portable spectral domain-optical coherence tomography (SD-OCT). DESIGN: Prospective, observational case series. PARTICIPANTS: Thirty-one prematurely born neonates, 9 ... Full text Link to item Cite

Intravitreal bevacizumab for macular edema due to central retinal vein occlusion: perfused vs. ischemic and early vs. late treatment.

Journal Article Curr Eye Res · December 2011 PURPOSE/AIMS: This study investigates the efficacy of intravitreal bevacizumab (IVB) for cystoid macular edema (CME) secondary to central retinal vein occlusion (CRVO). Subgroup analysis was performed comparing early (within 90 days of CRVO onset) and late ... Full text Link to item Cite

Pars plana vitrectomy, fluocinolone acetonide implantation, and silicone oil infusion for the treatment of chronic, refractory uveitic hypotony.

Journal Article Am J Ophthalmol · November 2011 Featured Publication PURPOSE: To assess the feasibility and outcomes of combining fluocinolone acetonide sustained drug delivery implant insertion, pars plana vitrectomy, and silicone oil infusion to treat patients with chronic, refractory ocular hypotony resulting from uveiti ... Full text Link to item Cite

Recovery of the neurosensory retina after macular translocation surgery is independent of preoperative macular sensitivity in neovascular age-related macular degeneration.

Journal Article Retina · September 2011 Featured Publication PURPOSE: To directly assess the recovery of the retina overlying choroidal neovascularization in neovascular age-related macular degeneration and to understand the relationship between macular sensitivity and visual functional measures and retinal structur ... Full text Link to item Cite

The role of bimatoprost eyelash gel in chemotherapy-induced madarosis: an analysis of efficacy and safety.

Journal Article Int J Trichology · July 2011 OBJECTIVES: Breast cancer patients suffer from madarosis (loss of eyelashes) due to chemotherapy side effects. An effective treatment or prevention for alopecia or madarosis induced by chemotherapy is not available. Potential drug side effects of bimatopro ... Full text Link to item Cite

Ranibizumab and bevacizumab for neovascular age-related macular degeneration.

Journal Article N Engl J Med · May 19, 2011 BACKGROUND: Clinical trials have established the efficacy of ranibizumab for the treatment of neovascular age-related macular degeneration (AMD). In addition, bevacizumab is used off-label to treat AMD, despite the absence of similar supporting data. METHO ... Full text Link to item Cite

Midterm results of osteochondral lesions of the talar shoulder treated with fresh osteochondral allograft transplantation.

Journal Article J Bone Joint Surg Am · April 6, 2011 Featured Publication BACKGROUND: With osteochondral lesions of the talar shoulder, their size, the articular cartilage geometry, and the loss of the medial or lateral articular buttress often preclude treatment with traditional osteochondral autograft techniques. We hypothesiz ... Full text Link to item Cite

Evaluation of the ICare rebound tonometer as a home intraocular pressure monitoring device.

Journal Article J Glaucoma · February 2011 PURPOSE: (a) To investigate whether the ICare rebound tonometer can provide accurate measurements of intraocular pressure (IOP) in the hands of an inexperienced user compared with ICare measurements and Goldmann tonometry by a trained technician and (b) to ... Full text Link to item Cite

Association between ST segment Resolution following Fibrinolytic therapy or Intracoronary stenting, and Reinfarction in the same myocardial region in the DANAMI-2 study population.

Journal Article Cardiovasc Revasc Med · 2011 Featured Publication BACKGROUND: ST-segment resolution has long been used as one of several clinical markers of response to reperfusion therapy. With the use of the DANish trial in Acute Myocardial Infarction-2 (DANAMI-2) database, this case-control study tests the hypothesis ... Full text Link to item Cite

Use of fundus autofluorescence images to predict geographic atrophy progression.

Journal Article Retina · January 2011 Featured Publication PURPOSE: Fundus autofluorescence imaging has been shown to be helpful in predicting progression of geographic atrophy (GA) secondary to age-related macular degeneration. We assess the ability of fundus autofluorescence imaging to predict rate of GA progres ... Full text Link to item Cite

Correlation of apparent diffusion coefficient and fractional anisotropy values in the developing infant brain.

Journal Article AJR Am J Roentgenol · December 2010 OBJECTIVE: The purpose of our study was to correlate decrease in apparent diffusion coefficient (ADC) and increase in fractional anisotropy (FA) in various white matter (WM) regions using diffusion tenor imaging (DTI) within the first year of life. MATERIA ... Full text Link to item Cite

Timing of definitive fixation of severe tibial plateau fractures with compartment syndrome does not have an effect on the rate of infection.

Journal Article J Trauma · December 2010 Featured Publication BACKGROUND: Tibial plateau fractures with associated compartment syndrome are severe injuries with elevated infection rates. The objective of this article was to analyze whether there is an association between infection and the timing of definitive fractur ... Full text Link to item Cite

Severe obesity is associated with symptomatic presentation, higher parathyroid hormone levels, and increased gland weight in primary hyperparathyroidism.

Journal Article J Clin Endocrinol Metab · November 2010 CONTEXT: A relationship between primary hyperparathyroidism (PHPT) and obesity has been observed but is incompletely understood. Furthermore, obesity has been associated with vitamin D deficiency, suggesting that the three conditions may be linked. OBJECTI ... Full text Link to item Cite

The effect of alpha1-adrenergic receptor antagonist tamsulosin (Flomax) on iris dilator smooth muscle anatomy.

Journal Article Ophthalmology · September 2010 Featured Publication PURPOSE: To characterize and determine the effect of tamsulosin (Flomax) on the human iris dilator muscle anatomy. DESIGN: Retrospective, case-control study. PARTICIPANTS: This study comprised 51 cadaveric eyes from 27 patients (14 with a history of tamsul ... Full text Link to item Cite

Use of decrease in apparent diffusion coefficient values to predict infarct age.

Journal Article Emerg Radiol · September 2010 Featured Publication The purpose of the study was to determine the ability to predict infarct age based on decrease in apparent diffusion coefficient (ADC) values. We retrospectively identified 94 individuals (age range 16 years to 91 years; mean 63.7 + 14.1 years) who underwe ... Full text Link to item Cite

Selective laser trabeculoplasty reduces mean IOP and IOP variation in normal tension glaucoma patients.

Journal Article Clin Ophthalmol · August 9, 2010 Featured Publication PURPOSE: To evaluate the effect of selective laser trabeculoplasty (SLT) in normal tension glaucoma (NTG) patients. PATIENTS AND METHODS: A retrospective review was performed of NTG patients who had undergone SLT at the Duke University Eye Center between 1 ... Full text Link to item Cite

Bimatoprost 0.03% gel for cosmetic eyelash growth and enhancement.

Journal Article J Cosmet Dermatol · June 2010 Featured Publication OBJECTIVE: To evaluate a bimatoprost gel for enhancing eyelash growth, adverse effects, and change in intraocular pressure (IOP). METHODS: Prospective, double-masked, randomized controlled study. Fifty-two patients without ocular disease were assigned a co ... Full text Link to item Cite

Vision-related quality of life in persons with unilateral branch retinal vein occlusion using the 25-item National Eye Institute Visual Function Questionnaire.

Journal Article Br J Ophthalmol · March 2010 AIM: To evaluate vision-related quality of life in persons with branch retinal vein occlusion (BRVO) using the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25). DESIGN: Observational, cross-sectional, interviewer-administered study ... Full text Link to item Cite

Defining criteria for selective operative management of pancreatic cystic lesions: does size really matter?

Journal Article J Gastrointest Surg · February 2010 Featured Publication INTRODUCTION: Proposed criteria for resection of pancreatic cystic lesions have included symptoms, size (>3 cm), and suspicious features by endoscopic ultrasound (EUS). The objective of this study was to evaluate risk factors for malignancy in a large seri ... Full text Link to item Cite

Eyelash growth after enucleation and evisceration surgery.

Journal Article Ophthalmic Plast Reconstr Surg · 2010 Featured Publication Acquired eyelash hypertrichosis is associated with medications, systemic diseases, and ocular inflammation. The authors present a study showing that eyelash length is significantly longer following enucleation and evisceration surgery compared with the con ... Full text Link to item Cite

Prevalence and incidence of urinary incontinence in a diverse population of women with noncancerous gynecologic conditions.

Journal Article Female Pelvic Med Reconstr Surg · 2010 OBJECTIVE: To determine the prevalence and incidence of urinary incontinence (UI) in a diverse cohort of women presenting with noncancerous gynecologic conditions and to assess factors associated with UI prevalence and incidence. METHODS: We conducted a se ... Full text Link to item Cite

Effects of reflected CO2 laser energy on operative field materials: risks to patients and operating room personnel.

Journal Article Ophthalmic Plast Reconstr Surg · 2010 This study investigates the effects of specularly and diffusely reflected CO2 laser energy on operative field materials. The CO2 laser was reflected off the sandblasted and polished surfaces of an eyelid plate and a wet cotton gauze pad. The laser was aime ... Full text Link to item Cite

Cosmetic surgery survey of american society of oculoplastic and reconstructive surgery members and a 6-year comparison.

Journal Article Ophthalmic Plast Reconstr Surg · 2010 PURPOSE: To examine the current cosmetic practices of American Society of Oculoplastic and Reconstructive Surgery members using a survey and compare those results with a similar survey that was performed 6 years prior, and to determine the types and breadt ... Full text Link to item Cite

Latanoprost in pediatric glaucoma--pediatric exposure over a decade.

Journal Article J AAPOS · December 2009 Featured Publication BACKGROUND: Although numerous studies of latanoprost in adult glaucoma have shown it to be an effective hypotensive agent with a low incidence of side effects, these issues have not been well studied in pediatric glaucomas. The purpose of the current study ... Full text Link to item Cite

Change in urethral sphincter neuromuscular function during pregnancy persists after delivery.

Journal Article Am J Obstet Gynecol · November 2009 Featured Publication OBJECTIVE: The purpose of this study was to assess the effect of pregnancy and first vaginal delivery on urethral striated sphincter neuromuscular function. STUDY DESIGN: Quantitative electromyographic (EMG) interference pattern analysis of the urethral sp ... Full text Link to item Cite

Retinal thickening in iridocyclitis.

Journal Article Am J Ophthalmol · September 2009 Featured Publication PURPOSE: To determine the frequency of retinal thickening (RT) in eyes with iridocyclitis and to examine the correlations among anterior chamber (AC) inflammation, RT, and visual acuity. DESIGN: Retrospective, observational case series. METHODS: Records we ... Full text Link to item Cite

Spectral domain optical coherence tomography imaging of geographic atrophy margins.

Journal Article Ophthalmology · September 2009 Featured Publication OBJECTIVE: To test in vivo whether spectral domain optical coherence tomography (SD-OCT) provides adequate resolution for reproducible measurement of photoreceptor (PR) layer at the margins of geographic atrophy (GA), and if it delineates the relationship ... Full text Link to item Cite

Socioeconomic status predicts outcomes from NSCLC

Conference JOURNAL OF THORACIC ONCOLOGY · September 1, 2009 Link to item Cite

Eyebrow and eyelid dimensions: an anthropometric analysis of African Americans and Caucasians.

Journal Article Plast Reconstr Surg · August 2009 BACKGROUND: Knowledge of the average dimensions of periocular features based on age, gender, and race is critical for surgeons so that complications can be avoided and ideal outcomes can be achieved. In this study, the authors sought to determine whether s ... Full text Link to item Cite

Levator ani denervation and reinnervation 6 months after childbirth.

Journal Article Am J Obstet Gynecol · May 2009 Featured Publication OBJECTIVE: The objective of the study was to assess the prevalence of levator ani denervation and reinnervation 6 months after the first delivery. STUDY DESIGN: Ninety-six primigravida women underwent quantitative electromyography of the levator ani during ... Full text Link to item Cite

Pars plana vitrectomy, internal limiting membrane peeling, and panretinal endophotocoagulation for macular edema secondary to central retinal vein occlusion.

Journal Article Am J Ophthalmol · April 2009 PURPOSE: To investigate the visual and anatomic outcomes in eyes with cystoid macular edema (CME) resulting from central retinal vein occlusion (CRVO) that underwent pars plana vitrectomy, internal limiting membrane peeling, and panretinal endolaser photoc ... Full text Link to item Cite

Multisite analysis of 177 consecutive primary breast augmentations: predictors for reoperation.

Journal Article Aesthet Surg J · 2009 Featured Publication BACKGROUND: Plastic surgeons and manufacturers of breast implants have been examining the complication and reoperation rates of primary breast augmentations for more than 18 years. The seemingly high rates reported by the manufacturers to the United States ... Full text Link to item Cite

Glaucoma patients' trust in the physician.

Journal Article J Ophthalmol · 2009 Objectives. To describe glaucoma patients' trust in the physician and to test the hypothesis that increased interpersonal trust is associated with increased medication adherence. Methods. One hundred ninety-five subjects with open-angle glaucoma seen by mu ... Full text Link to item Cite

Survival analysis

Chapter · December 1, 2008 Survival analysis is concerned with time to the occurrence of an event, such as death, recurrence or disease, or failure of an implanted medical device. Computing only the overall proportion surviving the event neglects the important aspect of time. We nee ... Full text Cite

English translations of statistical terms, study designs, and methods of analysis

Chapter · December 1, 2008 This chapter contains plain-language summaries of statistical terms, study designs, and methods of analysis. To provide the quickest access to terms, they are arranged in alphabetical order under each of these three headings. In keeping with our goal of tr ... Full text Cite

Pediatric recurrent acute otitis media

Chapter · December 1, 2008 A computerized Ovid search of MEDLINE 1966-Junuary 2004 was performed. The terms otitis media and antibiotics were exploded and the resulting articles were cross-referenced, yielding 1947 trials. Given the known richnes sof the otitis media literature and ... Full text Cite

Intracranial pressure in primary open angle glaucoma, normal tension glaucoma, and ocular hypertension: a case-control study.

Journal Article Invest Ophthalmol Vis Sci · December 2008 Featured Publication PURPOSE: To compare intracranial pressure (ICP) in subjects with primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG; subset of POAG), and ocular hypertension (OHT) with that in subjects with no glaucoma. METHODS: The study was a retrospective ... Full text Link to item Cite

Recurrent choroidal neovascularization after macular translocation surgery with 360-degree peripheral retinectomy.

Journal Article Retina · October 2008 PURPOSE: To evaluate the pattern of age-related macular degeneration in the new foveal location after macular translocation surgery with 360 degree peripheral retinectomy for neovascular age-related macular degeneration. METHODS: Clinical data, fundus phot ... Full text Link to item Cite

Fluocinolone acetonide sustained drug delivery device for chronic central retinal vein occlusion: 12-month results.

Journal Article Am J Ophthalmol · August 2008 PURPOSE: To determine treatment outcomes of a long-acting intravitreal fluocinolone acetonide sustained drug delivery implant in eyes with central retinal vein occlusion (CRVO) and chronic refractory macular edema. DESIGN: Prospective, noncomparative, inte ... Full text Link to item Cite

Treatment of neovascular age-related macular degeneration with intravitreal bevacizumab: efficacy of three consecutive monthly injections.

Journal Article Am J Ophthalmol · July 2008 PURPOSE: To report the efficacy of treatment of neovascular age-related macular degeneration (AMD) with intravitreal bevacizumab (Avastin; Genentech, Inc, South San Francisco, California, USA) when administered in a series of three monthly injections follo ... Full text Link to item Cite

Photodynamic therapy for predominantly hemorrhagic lesions in neovascular age-related macular degeneration.

Journal Article Am J Ophthalmol · June 2008 Featured Publication PURPOSE: To evaluate the response of eyes treated with photodynamic therapy (PDT) for predominantly hemorrhagic lesions in neovascular age-related macular degeneration (NVAMD). DESIGN: Consecutive, interventional case series. METHODS: A retrospective revie ... Full text Link to item Cite

Health literacy and vision-related quality of life.

Journal Article Br J Ophthalmol · June 2008 BACKGROUND: Non-visual factors influence a person's vision-related quality of life (VRQoL). The purpose of this study was to assess the relationship between health literacy and VRQoL in glaucoma patients. METHODS: One hundred and ninety-five subjects with ... Full text Link to item Cite

Use of a standardized patient satisfaction questionnaire to assess the quality of care provided by ophthalmology residents.

Journal Article Ophthalmology · April 2008 PURPOSE: To develop and use a standardized patient satisfaction questionnaire (PSQ) to address two study questions: (1) What is the overall level of satisfaction with resident care? (2) Can the study questionnaire be used to detect differences in the level ... Full text Link to item Cite

A prospective study of early intraocular pressure changes after a single intravitreal triamcinolone injection.

Journal Article J Glaucoma · March 2008 PURPOSE: To prospectively monitor intraocular pressure (IOP) and gonioscopy changes within the first month after a single 4-mg intravitreal injection of triamcinolone acetonide (IVK) (Kenalog, Briston-Meyers Squibb, New York). DESIGN: Prospective comparati ... Full text Link to item Cite

Assessment of visual status of the Aeta, a hunter-gatherer population of the Philippines (an AOS thesis).

Journal Article Trans Am Ophthalmol Soc · 2008 PURPOSE: A screening study was performed to assess levels of visual impairment and blindness among a representative sample of older members of the Aeta, an indigenous hunter-gatherer population living on the island of Luzon in the Philippines. METHODS: Unr ... Link to item Cite

Safety and efficacy of silicone rod frontalis suspension surgery for childhood ptosis repair.

Journal Article J Pediatr Ophthalmol Strabismus · 2008 PURPOSE: To evaluate the safety and efficacy of silicone rod frontalis suspension surgery for childhood ptosis. METHODS: The authors retrospectively studied 89 consecutive children (110 eyelids) who had silicone rod frontalis suspension surgery for ptosis ... Full text Link to item Cite

Patient-preferred sites of restylane injection in periocular and facial soft-tissue augmentation.

Journal Article Ophthalmic Plast Reconstr Surg · 2008 PURPOSE: To determine patient-preferred injection sites and frequency for facial volume augmentation with nonanimal stabilized hyaluronic acid (Restylane). METHODS: : The authors retrospectively reviewed the records of 145 consecutive patients who received ... Full text Link to item Cite

Sample size for comparing correlated concordance rates.

Journal Article J Biopharm Stat · 2008 Featured Publication We consider collecting the measurements of a gold standard and two methods with error from each site of subjects. We propose an asymptotic test statistic to compare the concordance rates of two methods with the gold standard and a closed-form sample size f ... Full text Link to item Cite

The clinical utility of dynamic contour tonometry and ocular pulse amplitude.

Journal Article J Glaucoma · December 2007 PURPOSE: To determine if ocular pulse amplitude (OPA) as measured by dynamic contour tonometry (DCT) is related to severity of glaucoma, and if intraocular pressure (IOP) as measured by DCT is related to central corneal thickness (CCT). METHODS: Patients w ... Full text Link to item Cite

Optical coherence tomography reader agreement in neovascular age-related macular degeneration.

Journal Article Am J Ophthalmol · July 2007 PURPOSE: To determine the interreader and intrareader agreement at the Optical Coherence Tomography (OCT) Reading Center at Duke for images produced for an interventional neovascular age-related macular degeneration (AMD) clinical trial. DESIGN: Retrospect ... Full text Link to item Cite

In response [3]

Other Journal of Glaucoma · March 1, 2007 Full text Cite

Analysis of bacterial cultures in infectious keratitis, 1997 to 2004.

Journal Article Am J Ophthalmol · December 2006 PURPOSE: To review bacterial culture results in infectious keratitis at a tertiary referral center. DESIGN: Retrospective case series. METHODS: Analysis of Gram stain, bacterial culture, and targeted antibiotic sensitivities of all cases of presumed infect ... Full text Link to item Cite

Retrospective review of eyes with neovascular age-related macular degeneration treated with photodynamic therapy with verteporfin and intravitreal triamcinolone.

Journal Article Ann Acad Med Singap · October 2006 AIM: To review the outcomes of eyes with neovascular age-related macular degeneration (AMD) treated with photodynamic therapy (PDT) with verteporfin and intravitreal triamcinolone acetonide injection. MATERIALS AND METHODS: We retrospectively reviewed the ... Link to item Cite

Quality of life of patients with otitis media and caregivers: a multicenter study.

Journal Article Laryngoscope · October 2006 OBJECTIVE: The objective of this study was to determine the quality of life of otitis media (OM) patients and their caregivers. STUDY DESIGN: A cross-sectional study was conducted at 11 otolaryngology and five pediatric clinics in the United States between ... Full text Link to item Cite

Health literacy and adherence to glaucoma therapy.

Journal Article Am J Ophthalmol · August 2006 PURPOSE: To describe the health literacy of subjects with open angle glaucoma and to investigate the hypothesis that low health literacy is associated with poor glaucoma medication adherence. DESIGN: Cross-sectional patient survey and concomitant chart rev ... Full text Link to item Cite

Efficacy of low-release-rate fluocinolone acetonide intravitreal implants to treat experimental uveitis.

Journal Article Arch Ophthalmol · July 2006 OBJECTIVE: To determine the efficacy of 0.5-mg and 0.1-mg sustained-release fluocinolone acetonide intravitreal implants to inhibit ocular inflammation in a rabbit model of severe uveitis. METHODS: The in vitro pharmacokinetic profile of both the 0.5-mg an ... Full text Link to item Cite

Longitudinal changes in central corneal thickness and their relation to glaucoma status: an 8 year follow up study.

Journal Article Br J Ophthalmol · June 2006 Featured Publication AIMS: To determine if central corneal thickness (CCT) changes over time and if this change relates to glaucoma progression. METHODS: 39 patients (64 eyes) with open angle glaucoma, ocular hypertension, glaucoma suspect status, or a normal eye examination w ... Full text Link to item Cite

Central corneal thickness in children: stability over time.

Journal Article Am J Ophthalmol · May 2006 PURPOSE: To evaluate central corneal thickness (CCT) in children over time. DESIGN: Prospective observational case series. METHODS: CCT was measured by ultrasonic pachymetry in 69 eyes of 38 subjects age 3 to 14 years recruited from the Duke University Eye ... Full text Link to item Cite

Contents

Journal Article Otolaryngology–Head and Neck Surgery · April 2006 Full text Cite

Clinical practice guideline: acute otitis externa.

Journal Article Otolaryngol Head Neck Surg · April 2006 OBJECTIVE: This guideline provides evidence-based recommendations to manage diffuse acute otitis externa (AOE), defined as generalized inflammation of the external ear canal, which may also involve the pinna or tympanic membrane. The primary purpose is to ... Full text Link to item Cite

Central retinal vein occlusion in patients treated with long-term warfarin sodium (Coumadin) for anticoagulation.

Journal Article Retina · March 2006 PURPOSE: To describe the clinical features of persons who developed central retinal vein occlusion (CVO) while being treated with Coumadin for chronic anticoagulation. METHODS: In a retrospective, comparative, noninterventional case series of patients diag ... Full text Link to item Cite

Intravitreal triamcinolone for cystoid macular edema related to branch retinal vein occlusion.

Journal Article Ann Ophthalmol (Skokie) · 2006 We retrospectively evaluated the effectiveness of intravitreal triamcinolone in treating 19 eyes with macular edema related to branch retinal vein occlusion (BRVO). Eyes with nonischemic BRVO respond more favorably than those with ischemic BRVO. A single i ... Full text Link to item Cite

Trends in the indications for penetrating keratoplasty, 1980-2001.

Journal Article Cornea · October 2005 PURPOSE: To study the leading indications and changing trends for penetrating keratoplasty (PK) over the past 3 decades. METHODS: This is a retrospective review of 696 cases of PK. The indications for PKs performed at the Duke University Eye Center during ... Full text Link to item Cite

High failure rate associated with 180 degrees selective laser trabeculoplasty.

Journal Article J Glaucoma · October 2005 Featured Publication PURPOSE: To determine the efficacy of selective laser trabeculoplasty (SLT) in a tertiary care referral center. PATIENTS AND METHODS: In this retrospective study of selective laser trabeculoplasty performed by five physicians, 94 eyes from 94 patients were ... Full text Link to item Cite

Risk factors for progression to penetrating keratoplasty in patients with keratoconus.

Journal Article Am J Ophthalmol · October 2005 PURPOSE: To determine clinical and demographic risk factors for corneal transplantation in keratoconus patients. DESIGN: Case control study. SETTING: Tertiary referral center. STUDY POPULATION: All keratoconic eyes presenting to the Duke University Eye Cen ... Full text Link to item Cite

Influence of age, race, sex, and socioeconomic status on false-negative rates of visual fields in glaucoma

Journal Article Asian Journal of Ophthalmology · September 19, 2005 Aim: An increased frequency of false-negative rates for visual fields in glaucoma has been associated with worse visual field status. This study examines whether this finding might also vary according to age, race, sex, or socioeconomic status - demographi ... Cite

Effects of cholesterol-lowering statins on the aqueous humor outflow pathway.

Journal Article Invest Ophthalmol Vis Sci · July 2005 PURPOSE: To investigate the effects of cholesterol-lowering statin drugs on trabecular meshwork cellular properties and aqueous humor outflow. METHODS: Primary cell cultures of porcine trabecular meshwork (PTM) and ciliary body (PCB) were treated with eith ... Full text Link to item Cite

Macular and retinal nerve fiber layer analysis of normal and glaucomatous eyes in children using optical coherence tomography.

Journal Article Am J Ophthalmol · March 2005 Featured Publication PURPOSE: To evaluate macular and nerve fiber layer (NFL) thickness in normal and glaucomatous eyes of children 3 to 17 years old using optical coherence tomography (OCT-3). DESIGN: Observational cross-sectional study. METHODS: One hundred fifty-six eyes of ... Full text Link to item Cite

OCT reading center inter- and intra-grader agreement for diabetic macular edema

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · January 1, 2005 Link to item Cite

Cellular senescence in the glaucomatous outflow pathway.

Journal Article Exp Gerontol · 2005 The mechanisms responsible for the progressive malfunction of the trabecular meshwork (TM)-Schlemm's canal (SC) conventional outflow pathway tissue in primary open angle glaucoma (POAG) are still not fully understood. To determine whether POAG is character ... Full text Link to item Cite

Vision-related quality of life in patients with bilateral severe age-related macular degeneration.

Journal Article Ophthalmology · January 2005 PURPOSE: To determine the quality of life (QOL) of patients with bilateral severe age-related macular degeneration (AMD) before macular translocation with 360 degrees peripheral retinectomy. DESIGN: Prospective, consecutive, noncomparative case series. MET ... Full text Link to item Cite

Evaluation of image artifact produced by optical coherence tomography of retinal pathology.

Journal Article Am J Ophthalmol · January 2005 PURPOSE: To determine the frequency and type of optical coherence tomography (OCT) fast macular thickness map (FMTM) scan artifacts, and whether these artifacts depend on patient diagnosis, demographics, and ocular therapy. DESIGN: Retrospective observatio ... Full text Link to item Cite

Impact of fluorescein angiographic characteristics of macular lesions on outcomes after macular translocation 360 degree surgery in eyes with age-related macular degeneration.

Journal Article Retina · 2005 PURPOSE: To evaluate the relationship between preoperative lesion size and composition and visual outcomes at 1 year after macular translocation surgery with 360 degree peripheral retinectomy (MT360) for neovascular age-related macular degeneration (AMD). ... Full text Link to item Cite

Quality of life after macular translocation with 360 degrees peripheral retinectomy for age-related macular degeneration.

Journal Article Ophthalmology · January 2005 PURPOSE: To determine patients' quality of life (QOL) after macular translocation with 360 degrees peripheral retinectomy (MT360) for age-related macular degeneration. DESIGN: Prospective, interventional, consecutive, noncomparative case series. METHODS: A ... Full text Link to item Cite

Change in visual function after macular translocation with 360 degrees retinectomy for neovascular age-related macular degeneration.

Journal Article Ophthalmology · September 2004 Featured Publication OBJECTIVE: To measure the change in vision and visual outcomes at 12 months after macular translocation with 360 degrees retinectomy (MT360) and silicone oil tamponade in patients with bilateral vision loss resulting from subfoveal choroidal neovascular me ... Full text Link to item Cite

Clinical comparison of the Proview eye pressure monitor with the Goldmann applanation tonometer and the Tonopen.

Journal Article Arch Ophthalmol · August 2004 OBJECTIVE: To compare intraocular pressure (IOP) values obtained by patients using the new Proview eye pressure monitor (Bausch & Lomb, Rochester, NY) with those measured with the Goldmann tonometer and the TonoPen (Mentor, Norwell, Mass). METHODS: Eighty- ... Full text Link to item Cite

Improvement in near visual function after macular translocation surgery with 360-degree peripheral retinectomy.

Journal Article Graefes Arch Clin Exp Ophthalmol · July 2004 BACKGROUND: Information is limited on how specific near-vision skills are impacted by therapies such as macular translocation surgery with 360-degree retinectomy (MT360) for age-related macular degeneration (AMD). METHODS: Standardized tests of near vision ... Full text Link to item Cite

New dendritic adhesives for sutureless ophthalmic surgical procedures: in vitro studies of corneal laceration repair.

Journal Article Arch Ophthalmol · June 2004 OBJECTIVE: To compare a biodendrimer adhesive with a conventional suture for repairing linear and stellate corneal lacerations. METHODS: A keratome knife was used to create 4.1-mm full-thickness linear incisions (n = 36) and 3 x 4-mm full-thickness stellat ... Full text Link to item Cite

Prevalence and risk factors for proliferative vitreoretinopathy in eyes with rhegmatogenous retinal detachment but no previous vitreoretinal surgery.

Journal Article Am J Ophthalmol · June 2004 PURPOSE: To determine the prevalence of and risk factors for proliferatative vitreoretinopathy (PVR) in eyes with rhegmatogenous retinal detachment but no previous vitreoretinal surgery. DESIGN: Observational case series. METHODS: Prospective study. SETTIN ... Full text Link to item Cite

Effects of indocyanine green on the retina and retinal pigment epithelium in a porcine model of retinal hole.

Journal Article Retina · April 2004 PURPOSE: This study was designed to emulate human macular hole surgery and to test the effects of indocyanine green (ICG) on the retina and retinal pigment epithelium (RPE). METHODS: Yorkshire Cross pigs (n = 23) underwent vitrectomy, separation of the pos ... Full text Link to item Cite

Evaluation of image artifact produced by optical coherence tomography of retinal pathology

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · April 1, 2004 Link to item Cite

Silicone oil versus gas tamponade: author reply

Journal Article Ophthalmology · April 2004 Full text Cite

Demographic-related variations in posterior segment ocular sarcoidosis.

Journal Article Ophthalmology · February 2004 OBJECTIVE: To compare the frequency of posterior segment involvement (PSI), the prevalence of specific posterior segment signs, and visual acuity in ocular sarcoidosis by patient race, sex, and age. DESIGN: Retrospective, cross-sectional observational stud ... Full text Link to item Cite

Central corneal thickness as a risk factor for advanced glaucoma damage.

Journal Article Arch Ophthalmol · January 2004 OBJECTIVE: To determine if central corneal thickness (CCT) is related to the level of glaucoma severity at the initial examination. METHODS: The initial visit to a glaucoma specialist by consecutive patients with primary open-angle glaucoma from 1997 to 20 ... Full text Link to item Cite

Pharmacokinetics and safety of TP10, soluble complement receptor 1, in infants undergoing cardiopulmonary bypass.

Journal Article Am Heart J · January 2004 BACKGROUND: Increase in vascular permeability and multiorgan dysfunction after cardiopulmonary bypass (CPB) are barriers to successful cardiac surgery in infants. Complement inhibition with TP10, a C3/C5 convertase inhibitor (AVANT Immunotherapeutics, Need ... Full text Link to item Cite

Meta-analysis of plasma homocysteine, serum folate, serum vitamin B(12), and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease.

Journal Article Am J Ophthalmol · December 2003 PURPOSE: To assess the role of plasma total homocysteine (tHcy) levels, serum folate and vitamin B(12)levels, and homozygosity for the thermolabile methylenetetrahydrofolate reductase genotype (TT) as risk factors for retinal vascular occlusive disease. DE ... Full text Link to item Cite

Radial optic neurotomy as treatment for central retinal vein occlusion.

Journal Article Am J Ophthalmol · November 2003 PURPOSE: To review our initial experience with radial optic neurotomy as treatment for retinal vein occlusion. DESIGN: Interventional case series. PATIENT POPULATION: five patients (four with central retinal vein occlusion and one with hemiretinal vein occ ... Full text Link to item Cite

B-scan ultrasonography for the detection of macular thickening.

Journal Article Am J Ophthalmol · July 2003 Featured Publication PURPOSE: To report the sensitivity and specificity of B-scan ultrasonography to detect macular thickening. DESIGN: Observational case series. METHODS: Seventy-seven eyes of 40 consecutive patients (age range, 7-80 years) in a retinal specialty practice wer ... Full text Link to item Cite

Comparison of silicone oil versus gas tamponade in the treatment of idiopathic full-thickness macular hole.

Journal Article Ophthalmology · June 2003 PURPOSE: To compare anatomic and functional outcomes of macular hole surgery with either silicone oil or C(3)F(8) gas tamponade. DESIGN: Retrospective comparative interventional study. PARTICIPANTS: Fifty-four eyes of 51 patients underwent pars plana vitre ... Full text Link to item Cite

Central corneal thickness as a risk factor for advanced glaucoma damage

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · May 1, 2003 Link to item Cite

Correlation among retinal thickness, optic disc, and visual field in glaucoma patients and suspects: a pilot study.

Journal Article J Glaucoma · April 2003 OBJECTIVE: To correlate losses of retinal thickness in the perifoveal area in glaucoma as measured by the Retinal Thickness Analyzer (Talia Technology Ltd, Israel) with optic nerve and visual field changes in glaucoma patients and suspects. METHODS: Observ ... Full text Link to item Cite

Lensectomy and vitrectomy decrease the rate of photoreceptor loss in rhodopsin P347L transgenic pigs.

Journal Article Graefes Arch Clin Exp Ophthalmol · April 2003 BACKGROUND: Photoreceptor degeneration in retinitis pigmentosa (RP) runs an inevitable, gradually progressive course. A wide variety of growth factors of different origins have been shown to slow the rate of degeneration in some rodent models of RP. Recent ... Full text Link to item Cite

Ten-year surgical experience with childhood glaucoma.

Journal Article J Pediatr Ophthalmol Strabismus · 2003 Full text Link to item Cite

Visual outcomes following macular translocation with 360-degree peripheral retinectomy.

Journal Article Arch Ophthalmol · October 2002 Featured Publication OBJECTIVE: To evaluate visual outcomes following macular translocation with 360 degrees peripheral retinectomy in patients with subfoveal choroidal neovascularization secondary to age-related macular degeneration. METHODS: In a prospective study, 15 consec ... Full text Link to item Cite

Dissociation between hemodynamic changes and symptom improvement in patients with advanced congestive heart failure.

Journal Article Eur J Heart Fail · June 2002 Featured Publication BACKGROUND: Changes in hemodynamic measures often serve as surrogate end points in efficacy trials for advanced heart failure, although there are few objective data to support this practice. AIMS: We compared changes in hemodynamic variables vs. changes in ... Full text Link to item Cite

The effects of drying on central corneal thickness

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · May 1, 2002 Link to item Cite

Attitudes toward genetic testing for glaucoma: A survey of patients

Conference INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE · May 1, 2002 Link to item Cite

Prospective comparison of hemorrhagic complications after treatment with enoxaparin versus unfractionated heparin for unstable angina pectoris or non-ST-segment elevation acute myocardial infarction.

Journal Article Am J Cardiol · December 1, 2001 Patients with unstable angina pectoris (UAP) or non-ST-segment elevation acute myocardial infarction (AMI) are at risk of death or recurrent ischemic events, despite receiving aspirin and unfractionated heparin (UFH). This study investigates the effect of ... Full text Link to item Cite

Exploring health-related quality of life in patients with diseases of the ear, nose, and throat: a multicenter observational study.

Journal Article Otolaryngol Head Neck Surg · October 2001 OBJECTIVES: This study was undertaken to explore which diseases of the ear, nose, and throat impact daily functioning of patients in an outpatient setting and to observe how specific demographic variables affect health-related quality of life (HRQOL) in th ... Full text Link to item Cite

Hemodynamics as surrogate end points for survival in advanced heart failure: an analysis from FIRST.

Journal Article Am Heart J · June 2001 BACKGROUND: Hemodynamics often are used as surrogate end points in phase II trials of acute heart failure (HF). We reviewed the Flolan International Randomized Survival Trial (FIRST) database to identify the hemodynamic variables that best predict survival ... Full text Link to item Cite

Hemodynamic profiles of advanced heart failure: association with clinical characteristics and long-term outcomes.

Journal Article J Card Fail · June 2001 BACKGROUND: Classifying patients with advanced congestive heart failure (CHF) by baseline measures of congestion and perfusion has been used to estimate hemodynamic status and to select and titrate therapy. We describe clinical characteristics of 4 hemodyn ... Full text Link to item Cite

Predictors of recurrent ischemic events and death in unstable coronary artery disease after treatment with combination antithrombotic therapy.

Journal Article Am Heart J · June 2000 BACKGROUND: Patients with non-Q-wave acute coronary syndromes (ACS) have substantial rates of recurrent ischemic events, but prognostic studies have been small or preceded the routine use of aggressive combination antithrombotic therapy. We sought to ident ... Full text Link to item Cite

Efficacy and tolerability of lovastatin in 3390 women with moderate hypercholesterolemia.

Journal Article Ann Intern Med · June 1, 1993 OBJECTIVE: To evaluate the efficacy and safety of lovastatin in women with moderate hypercholesterolemia. DESIGN: The Expanded Clinical Evaluation of Lovastatin (EXCEL) Study, a multicenter, double-blind, diet- and placebo-controlled trial, in which partic ... Full text Link to item Cite

Expanded Clinical Evaluation of Lovastatin (EXCEL) study results. Effect of patient characteristics on lovastatin-induced changes in plasma concentrations of lipids and lipoproteins.

Journal Article Circulation · April 1992 BACKGROUND: Lovastatin produces consistent dose-related reductions in plasma levels of low density lipoprotein (LDL) cholesterol along with variable decreases in triglycerides and increases in high density lipoprotein (HDL) cholesterol. Patient characteris ... Full text Link to item Cite

Lovastatin and coadministered antihypertensive/cardiovascular agents.

Journal Article Hypertension · March 1992 Hypertension and hypercholesterolemia frequently coexist and may require concomitant drug treatments. The efficacy and safety profile of lovastatin given in the presence of antihypertensive medication was evaluated using patient subgroups identified in the ... Full text Link to item Cite

Update on the use of distal radial bone density measurements in prediction of hip and Colles' fracture risk.

Journal Article J Orthop Res · March 1990 Featured Publication A controversy has developed around the question as to whether bone density values from the distal radius can be used to accurately predict risk of future fractures. To address this question, two separate studies were undertaken: (a) Bone density was measur ... Full text Link to item Cite

Women in Statistics: Sesquicentennial Activities

Journal Article The American Statistician · 1990 Cite

A benefit of spinal manipulation as adjunctive therapy for acute low-back pain: a stratified controlled trial

Other Manuelle Medizin · January 1, 1990 Fifty-four subjects volunteered to participate in a controlled study contrasting spinal manipulation with spinal mobilization without the rotational forces and leverage required to move facet joints. All suffered from regional lowback pain for less than 1 ... Cite

Air pollution and lung cancer mortality in Harris County, Texas, 1979-1981.

Journal Article Am J Epidemiol · October 1988 Elevated lung cancer mortality rates in Harris County, Texas compared with other US counties and previously published reports that suggested a causal relation between air pollution and lung cancer in Houston prompted this ecologic analysis. A weighted regr ... Full text Link to item Cite

Correlates of systolic and diastolic blood pressure in men 40 to 59 years of age sampled from United States of America and Union of Soviet Socialist Republics Lipid Research Clinics populations.

Journal Article Am J Cardiol · May 1, 1988 The correlates of blood pressure (BP) were investigated in 2 samples using common protocols, one from a Union of Soviet Socialist Republics study in 2 locations and one from a United States of America study in 9 locations. Age, heart rate, Quetelet index, ... Full text Link to item Cite

An Example of Simultaneous Multivariate Linear Modelling of Among and Within Subject Variation

Journal Article Biometrical Journal · January 1, 1988 An example of simultaneous linear modelling of among and within subject variation through weighted least squares methods is presented as an alternative to standard multivariate analysis of variance techniques. The data pertain to a study of temporal charac ... Full text Cite

Medical disability assessment of the back pain patient for the Social Security Administration: the weighting of presenting clinical features.

Journal Article J Clin Epidemiol · 1988 We investigated how physicians use history and physical findings when assessing disability for low back pain. Thirty-six North Carolina physicians, either practitioners experienced in disability determinations (26) or employees of the Social Security disab ... Full text Link to item Cite

A benefit of spinal manipulation as adjunctive therapy for acute low-back pain: a stratified controlled trial.

Journal Article Spine (Phila Pa 1976) · September 1987 Fifty-four subjects volunteered to participate in a controlled study contrasting spinal manipulation with spinal mobilization without the rotational forces and leverage required to move facet joints. All suffered from regional low-back pain for less than 1 ... Link to item Cite

A benefit of spinal manipulation as adjunctive therapy for acute low-back pain: A stratified controlled trial

Journal Article Spine · January 1, 1987 Fifty-four subjects volunteered to participate in a controlled study contrasting spinal manipulation with spinal mobilization without the rotational forces and leverage required to move facet joints. All suffered from regional low-back pain for less than 1 ... Full text Cite

Age-related loss of bone mineral density in non-athletic and athletic women.

Journal Article Bone Miner · April 1986 Single and dual photon absorptiometry were performed at the mid-radius, distal radius and lumbar spine in 1105 non-athletic and 124 athletic Caucasian women aged 18-98 years. An age-related loss of bone mineral density in mg/cm2 (BMD) occurred at the three ... Link to item Cite

Populations and methods for assessing dyslipoproteinemia and its correlates. The Lipid Research Clinics Program Prevalence Study.

Journal Article Circulation · January 1986 This article presents the basic methods and populations of the Lipid Research Clinics (LRC) Program Prevalence Study. The purpose is to provide a frame of reference for the other articles in this monograph; hence, the populations and major data collected a ... Cite

Detection of dyslipoproteinemia with the use of plasma total cholesterol and triglyceride as screening tests. The Lipid Research Clinics Program Prevalence Study.

Journal Article Circulation · January 1986 The efficiency of screening for dyslipoproteinemias associated with hyperlipoproteinemia or with hypolipoproteinemia was examined in 8449 white examinees from the Lipid Research Clinics Prevalence Study. A two-stage lipid screening approach was used. A pos ... Link to item Cite

The association of dyslipoproteinemia with corneal arcus and xanthelasma. The Lipid Research Clinics Program Prevalence Study.

Journal Article Circulation · January 1986 The prevalence rates of xanthelasma and corneal arcus were computed for normolipidemic and dyslipoproteinemic participants in the Lipid Research Clinics population surveys. The prevalence of both xanthelasma and corneal arcus increased with age, was highes ... Link to item Cite

U.S.S.R. and U.S. nutrient intake, plasma lipids, and lipoproteins in men ages 40-59 sampled from Lipid Research Clinics populations.

Journal Article Prev Med · May 1985 Correlates of high-density lipoprotein (HDL) cholesterol and other lipids and lipoproteins were studied in white men ages 40-59 who were part of the 15% random sample recalled to Visit 2 of the Lipid Research Clinics Program Prevalence Study. Standardized ... Full text Link to item Cite