Scholars@Duke
Jonathan Charles Routh

Jonathan Charles Routh

Paul H. Sherman, M.D. Distinguished Associate Professor of Surgery
Urology
3831, Durham, NC 27710
200 Trent Dr, Durham, NC 27708

Selected Publications

Current clinical and surgical insights in the workup and management of Wilms tumor (nephroblastoma).

Journal Article Curr Opin Pediatr · October 1, 2025 PURPOSE OF REVIEW: Wilms tumor remains the most common renal malignancy in children. The treatment of Wilms tumor has evolved over the past decades improving overall survival while decreasing long-term, treatment-related sequelae. The purpose of this revie ... Full text Link to item Cite

Assessing and Optimizing Outcomes of Bladder Function

Journal Article Journal of Urology · October 1, 2025 Full text Cite

Furthering the Evidence for Antibiotic Stewardship in Urology

Journal Article Journal of Urology · August 1, 2025 Full text Cite

Nephrotoxicity Surveillance for Childhood and Young Adult Survivors of Cancer: Recommendations From the International Late Effects of Childhood Cancer Guideline Harmonization Group.

Journal Article J Clin Oncol · July 20, 2025 PURPOSE: Childhood, adolescent, and young adult (CAYA) survivors of cancer are at risk of nephrotoxicity. Surveillance guidelines are important for timely diagnosis and treatment of these survivors, which could slow the progression to higher stages of kidn ... Full text Link to item Cite

Impact of social determinants of health on fecal incontinence treatment in older women.

Journal Article Am J Obstet Gynecol · July 7, 2025 BACKGROUND: Many women with fecal incontinence do not seek care despite the availability of effective treatments. Factors influencing care-seeking for fecal incontinence are not well elucidated, and the role of social determinants of health in fecal incont ... Full text Link to item Cite

Challenging Dogma in Urology

Journal Article Journal of Urology · July 1, 2025 Full text Cite

Financial Toxicity in Spina Bifida: Development of a Patient and Caregiver Questionnaire.

Journal Article Urology · May 2025 OBJECTIVE: To develop and validate the first patient- and caregiver-reported measure of spina bifida-specific "financial toxicity" (SBFT), that is, the negative side effects of healthcare-related expenditures. Assessing financial toxicity is a growing area ... Full text Link to item Cite

Sentinel lymph node dissection during radical cystectomy for bladder adenocarcinoma following gastrocystoplasty.

Journal Article Urol Case Rep · May 2025 Patients with spina bifida are at increased risk of developing malignancy in the native or augmented bladder and tend to present with more advanced disease. Surgical guidelines for oncologic resections in patients with augmented bladders are not well descr ... Full text Link to item Cite

Lymph Node Staging and Treatment in Pediatric Patients With Soft Tissue Sarcomas: A Consensus Opinion From the Children's Oncology Group, European paediatric Soft Tissue Sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.

Journal Article Pediatr Blood Cancer · April 2025 Accurate staging of nodal involvement in pediatric sarcoma patients is important to determine correct systemic and local therapy, with the goal to reduce subsequent recurrences. However, differences in lymph node staging strategies, definitions, and treatm ... Full text Link to item Cite

Diagnostic Test Characteristics of Ultrasound-Based Hydronephrosis for Chronic Kidney Disease in Children and Adolescents With Myelomeningocele: Results From the UMPIRE and National Spina Bifida Patient Registry Cohort Studies.

Journal Article J Urol · March 2025 PURPOSE: Renal ultrasounds are performed in patients with myelomeningocele to screen for markers of kidney health, including hydronephrosis. We evaluated the diagnostic accuracy of hydronephrosis to screen for low kidney function defined by estimated glome ... Full text Link to item Cite

Editors' Choice

Journal Article Journal of Urology · March 1, 2025 Full text Cite

How Many Lymph Nodes are Enough in Paratesticular Rhabdomyosarcoma?

Journal Article J Pediatr Surg · February 2025 BACKGROUND: Treatment strategies for paratesticular rhabdomyosarcoma (PT RMS) are based on stage, which requires accurate lymph node (LN) evaluation. Previous methodology for determining quantity of LN for negative nodal status is based on LN positivity ra ... Full text Link to item Cite

Editors’ Choice

Journal Article Journal of Urology · December 1, 2024 Full text Cite

Jonathan C. Routh, MD, MPH.

Journal Article J Urol · November 2024 Full text Link to item Cite

Comparing binary & ordinal definitions of urinary & stool continence outcomes: Data from the National Spina Bifida Patient Registry.

Journal Article J Pediatr Urol · October 2024 INTRODUCTION: The National Spina Bifida Patient Registry (NSBPR) assesses bladder and bowel incontinence using ordinal categories, but prior NSBPR analyses employed binary classification. Our aims were to 1) perform the first NSBPR analysis of bladder and ... Full text Link to item Cite

Editors' Choice.

Journal Article J Urol · October 2024 Full text Link to item Cite

Editors' Choice.

Journal Article J Urol · August 14, 2024 Full text Link to item Cite

Editors' Choice.

Journal Article J Urol · August 2024 Full text Link to item Cite

Radiation-induced Sarcoma of the Prostate After Treatment for Rhabdomyosarcoma.

Journal Article Urology · July 2024 Rhabdomyosarcoma (RMS) is among the most common pediatric solid malignancies. Fusion-negative, embryonal RMS is the predominant histology among prostate and bladder lesions. Management strategies depend on the clinical stage and risk group. Although the op ... Full text Link to item Cite

Editors' Choice

Journal Article The Journal of urology · July 1, 2024 Full text Cite

Addition of temsirolimus to chemotherapy in children, adolescents, and young adults with intermediate-risk rhabdomyosarcoma (ARST1431): a randomised, open-label, phase 3 trial from the Children's Oncology Group.

Journal Article Lancet Oncol · July 2024 BACKGROUND: The Children's Oncology Group defines intermediate-risk rhabdomyosarcoma as unresected FOXO1 fusion-negative disease arising at an unfavourable site or non-metastatic FOXO1 fusion-positive disease. Temsirolimus in combination with chemotherapy ... Full text Link to item Cite

Pediatric urothelial cancer: a cross-sectional descriptive analysis of the National Cancer Database.

Journal Article Transl Androl Urol · May 31, 2024 BACKGROUND: Urothelial cancer is a rare pediatric malignancy; previous analyses suggest lower rates of recurrence and death as compared to adults. We analyzed pediatric bladder cancer information in a national database, hypothesizing that survival would be ... Full text Link to item Cite

The Persistency Index: a novel screening tool for identifying myofascial pelvic floor dysfunction in patients seeking care for lower urinary tract symptoms.

Journal Article Am J Obstet Gynecol · December 2023 BACKGROUND: Patients with myofascial pelvic floor dysfunction often present with lower urinary tract symptoms, such as urinary frequency, urgency, and bladder pressure. Often confused with other lower urinary tract disorders, this constellation of symptoms ... Full text Link to item Cite

Recurrent Papillary Bladder Tumors in a Boy With Lynch Syndrome.

Journal Article Urology · November 2023 Lynch syndrome (LS) is an autosomal dominant genetic disorder defined by germline mutations in one of four mismatch repair genes including PMS2, MLH2, MSH1, MSH2, or deletion in the EPCAM gene.1 The most common urologic manifestation of LS is upper tract u ... Full text Link to item Cite

Myofascial urinary frequency syndrome is a novel syndrome of bothersome lower urinary tract symptoms associated with myofascial pelvic floor dysfunction.

Journal Article Sci Rep · October 27, 2023 This study describes a novel, distinct phenotype of urinary symptoms named "myofascial urinary frequency syndrome" (MUFS) present in one-third of individuals presenting with urinary frequency. In addition to a characteristic symptom constellation suggestiv ... Full text Link to item Cite

Critical elements of pediatric rhabdomyosarcoma surgery.

Journal Article Semin Pediatr Surg · October 2023 Rhabdomyosarcoma (RMS), the most common soft tissue sarcoma in children, requires multimodal therapy which is determined by risk group stratification. Local control may be achieved by surgical resection, radiation, or both. Resection may occur upfront or f ... Full text Link to item Cite

Editorial Comment.

Journal Article J Urol · August 2023 Full text Link to item Cite

Single-port hidden incision endoscopic (HIdES) pediatric nephrectomy via pfannenstiel incision.

Conference J Pediatr Urol · June 2023 Laparoendoscopic single-site surgery (LESS) and hidden incision endoscopic surgery techniques are increasingly used in pediatric urology. For pediatric nephrectomy, access through a single Pfannenstiel incision is novel and may offer cosmetic benefit. In t ... Full text Link to item Cite

Editorial Comment.

Journal Article J Urol · June 2023 Full text Link to item Cite

Robot-assisted laparoscopic anterior urethral diverticulectomy.

Journal Article Int Urogynecol J · February 2023 INTRODUCTION AND HYPOTHESIS: A 31-year-old patient with a history of fetal sacrococcygeal teratoma requiring tumor resection and pelvic reconstruction in infancy presented with a 3-year history of recurrent vulvar abscesses and voiding dysfunction. Magneti ... Full text Link to item Cite

Medical management of neurogenic bladder in patients with spina bifida: A scoping review.

Journal Article J Pediatr Urol · February 2023 INTRODUCTION: Neurogenic bladder is a common source of morbidity in patients with spina bifida and can cause renal damage. Medical management may include imaging, urodynamic studies (UDS), laboratory testing, clean intermittent catheterization (CIC), and m ... Full text Link to item Cite

Causes of death among people with myelomeningocele: A multi-institutional 47-year retrospective study.

Journal Article J Pediatr Rehabil Med · 2023 PURPOSE: This study aimed to analyze organ system-based causes and non-organ system-based mechanisms of death (COD, MOD) in people with myelomeningocele (MMC), comparing urological to other COD. METHODS: A retrospective review was performed of 16 instituti ... Full text Open Access Link to item Cite

Variation in care between pediatric and adult patients presenting with nephrolithiasis to tertiary care pediatric emergency departments in the United States (2009-2020).

Journal Article J Pediatr Urol · December 2022 BACKGROUND: Individuals with nephrolithiasis frequently present to the Emergency Department (ED). Safety and quality principles are often applied in pediatric EDs to children presenting with nephrolithiasis, such as limiting ionizing radiation exposure and ... Full text Link to item Cite

Framing the picture: Impact of radiographic imaging on parental vesicoureteral reflux management preferences.

Journal Article J Pediatr Urol · October 2022 INTRODUCTION/OBJECTIVE: Given the variety of treatment options for vesicoureteral reflux (VUR), shared decision making between clinicians and parents is essential. Despite its importance, shared decision making is limited by the framing effect - people pro ... Full text Link to item Cite

Parents of Children With Newly Diagnosed Disorders of Sex Development Identify Major Concerns: A Qualitative Study.

Journal Article Urology · June 2022 OBJECTIVES: To develop a conceptual framework to understand and define the impact of DSD diagnosis and management from the perspective of parents of recently diagnosed children. METHODS: Semi-structured interviews were conducted with parents of children di ... Full text Link to item Cite

Variation in Definitions of Kidney Abnormality in Patients with Spina Bifida: A Systematic Scoping Review.

Journal Article J Urol · June 2022 PURPOSE: We systematically reviewed the variability in definitions of kidney abnormality (KA) outcomes in individuals with spina bifida (SB). MATERIALS AND METHODS: A systematic scoping review was conducted using MEDLINE, Embase™, Cochrane Library, CINAHL, ... Full text Link to item Cite

Financial toxicity among individuals with spina bifida and their families: A qualitative study and conceptual model.

Journal Article J Pediatr Urol · June 2022 INTRODUCTION: Spina bifida is the most common permanently disabling birth defect in the United States and requires lifelong, multi-specialty care. The cost of such care has the potential to result in financial toxicity - the 'objective financial burden' an ... Full text Link to item Cite

Predicting postoperative complications in pediatric surgery: A novel pediatric comorbidity index.

Journal Article J Pediatr Urol · June 2022 INTRODUCTION/BACKGROUND: Comorbidity-driven surgical risk assessment is essential for informed patient counseling, risk-stratification, and outcomes-based health-services research. Existing mortality-focused comorbidity indices have had mixed success at ri ... Full text Link to item Cite

Behavioral Economics in Urology: A Scoping Review.

Journal Article J Urol · June 2022 PURPOSE: Behavioral economics is the study of human behavior in the context of irrationality, self-control and self-interest. It has been leveraged in a variety of ways in health care, including efforts to decrease smoking, encourage weight loss and promot ... Full text Link to item Cite

Vaginal Complications after Cystectomy: Results from a Medicare Sample.

Journal Article J Urol · April 2022 PURPOSE: Cystectomy with a vaginal-sparing approach may be associated with unique complications specific to the female population. The objective of this study was to estimate the incidence of vaginal complications (defined to include vaginal prolapse, vagi ... Full text Link to item Cite

Combining adult with pediatric patient data to develop a clinical decision support tool intended for children: leveraging machine learning to model heterogeneity.

Journal Article BMC Med Inform Decis Mak · March 29, 2022 BACKGROUND: Clinical decision support (CDS) tools built using adult data do not typically perform well for children. We explored how best to leverage adult data to improve the performance of such tools. This study assesses whether it is better to build CDS ... Full text Open Access Link to item Cite

Machine Learning for Urodynamic Detection of Detrusor Overactivity.

Journal Article Urology · January 2022 OBJECTIVE: To develop a machine learning algorithm that identifies detrusor overactivity (DO) in Urodynamic Studies (UDS) in the spina bifida population. UDS plays a key role in assessment of neurogenic bladder in patients with spina bifida. Due to signifi ... Full text Link to item Cite

Sexual Function and Dysfunction in Individuals with Spina Bifida: A Systematic Review.

Journal Article Urology · October 2021 OBJECTIVE: To conduct a systematic review of self-reported experiences of sexual function and dysfunction in individuals with spina bifida (SB). MATERIALS AND METHODS: Medline, Embase, and Web of Science were systematically searched. Studies included conta ... Full text Link to item Cite

Urodynamic characteristics of neurogenic bladder in newborns with myelomeningocele and refinement of the definition of bladder hostility: Findings from the UMPIRE multi-center study.

Journal Article J Pediatr Urol · October 2021 INTRODUCTION: Infants with myelomeningocele are at risk for chronic kidney disease caused by neurogenic bladder dysfunction. Urodynamic evaluation plays a key role to risk stratify individuals for renal deterioration. OBJECTIVE: To present baseline urodyna ... Full text Link to item Cite

Translating pediatric urodynamics from clinic into collaborative research: Lessons and recommendations from the UMPIRE study group.

Journal Article J Pediatr Urol · October 2021 Pediatric patients present unique challenges in the performance and interpretation of urodynamic studies. Interpretation of urodynamics to guide clinical management at an institutional level is accepted as reliable. Challenges arise however when multi-site ... Full text Link to item Cite

Open versus minimally-invasive surgical techniques in pediatric renal tumors: A population-level analysis of in-hospital outcomes.

Journal Article J Pediatr Urol · August 2021 INTRODUCTION: Minimally-invasive surgery (MIS) has been adopted slowly in pediatric oncology. We attempted to describe contemporary national trends in MIS use; we hypothesized that adolescents (who are more likely to have relatively small renal cell carcin ... Full text Link to item Cite

Incidence of Urinary Tract Infections in Newborns with Spina Bifida-Is Antibiotic Prophylaxis Necessary?

Journal Article J Urol · July 2021 PURPOSE: Urinary tract infections commonly occur in patients with spina bifida and pose a risk of renal scarring. Routine antibiotic prophylaxis has been utilized in newborns with spina bifida to prevent urinary tract infections. We hypothesized that proph ... Full text Link to item Cite

Decreasing tracheostomy placement in hospitalized pediatric patients with subglottic stenosis - Kids' Inpatient Database (KID) analysis.

Journal Article Int J Pediatr Otorhinolaryngol · July 2021 OBJECTIVES: We aimed to assess procedural trends for tracheostomy placement in the management of children with subglottic stenosis. We hypothesize that with increased use of less invasive airway interventions for subglottic stenosis, tracheostomy may be pe ... Full text Link to item Cite

Pediatric Urology.

Journal Article J Urol · July 2021 Full text Link to item Cite

Utility estimation for neurogenic bowel dysfunction in the general population.

Journal Article J Pediatr Urol · June 2021 BACKGROUND: Neurogenic bowel dysfunction (NBD) affects over 80% of individuals with spina bifida causing bowel incontinence and/or constipation. NBD is also associated with decreased quality of life, depression, anxiety, and decreased employment/educationa ... Full text Link to item Cite

Editorial Comment.

Journal Article J Urol · June 2021 Full text Link to item Cite

Majority of females with a life-long experience of CAH and parents do not consider females with CAH to be intersex.

Journal Article J Pediatr Urol · April 2021 INTRODUCTION: To assess opinions of females with CAH, and parents of females with CAH, about designating this population "intersex," particularly in legislation about genital surgery during childhood. METHODS: We conducted a mixed-methods (quantitative and ... Full text Link to item Cite

Editorial Comment.

Journal Article J Urol · April 2021 Full text Link to item Cite

Surgical management of paratesticular rhabdomyosarcoma: A consensus opinion from the Children's Oncology Group, European paediatric Soft tissue sarcoma Study Group, and the Cooperative Weichteilsarkom Studiengruppe.

Journal Article Pediatr Blood Cancer · April 2021 The treatment of paratesticular rhabdomyosarcoma (PT-RMS) has varied over time and by cooperative group. The International Soft Tissue Sarcoma Database Consortium (INSTRuCT) is a collaboration of the Children's Oncology Group (COG) Soft Tissue Sarcoma Comm ... Full text Link to item Cite

Immune Expression in Children With Vesicoureteral Reflux: A Pilot Study.

Journal Article Urology · February 2021 OBJECTIVE: To perform an exploratory, descriptive pilot study of the systemic and local immune environment in patients with vesicoureteral reflux (VUR) and bladder-bowel dysfunction (BBD). METHODS: Consecutive children with VUR undergoing intravesical uret ... Full text Link to item Cite

Parental preferences for vesicoureteral reflux treatment: Profile case best-worst scaling.

Journal Article J Pediatr Urol · February 2021 INTRODUCTION: Vesicoureteral reflux is a common pediatric urologic condition that often has several reasonable treatment options depending on condition severity. In order to choose the best treatment for their child, parents are expected to make judgements ... Full text Link to item Cite

Benefit of delayed primary excision in rhabdomyosarcoma: A report from the Children's Oncology Group.

Journal Article Cancer · January 15, 2021 BACKGROUND: Most children with intermediate-risk rhabdomyosarcoma (RMS) have gross disease (group III) at the initiation of chemotherapy. Delayed primary excision (DPE) after induction chemotherapy allows for a reduction in adjuvant radiation dose, but wit ... Full text Link to item Cite

The Importance of Early Diagnosis and Management of Pediatric Neurogenic Bladder Dysfunction.

Journal Article Res Rep Urol · 2021 Neurogenic bladder dysfunction is a major source of urologic morbidity in children, especially in those with spina bifida (SB). Complications from progression of bladder dysfunction can include urinary tract infections (UTIs), urinary incontinence, upper t ... Full text Open Access Link to item Cite

Association between race and in-hospital outcomes in children with spina bifida following inpatient urologic surgery.

Journal Article J Pediatr Rehabil Med · 2021 PURPOSE: Post-operative complication rates may vary among racial and/or ethnic groups and have not been previously described in individuals with spina bifida (SB) undergoing urologic surgery. The aim of this study was to compare in-hospital complication fr ... Full text Link to item Cite

Impact of local control and surgical lymph node evaluation in localized paratesticular rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee.

Journal Article Int J Cancer · December 1, 2020 Paratesticular rhabdomyosarcoma (PT-RMS) carries a favorable prognosis, but questions persist regarding optimal management. Our goal was to determine the importance of primary tumor resection and surgical assessment of retroperitoneal lymph nodes during st ... Full text Link to item Cite

Minimally invasive pediatric oncology for renal malignancies

Chapter · November 25, 2020 Minimally invasive surgery (MIS) is increasingly used in adult tumor resections and has been shown to be associated with reduced pain and reduced length of stay, with similar oncologic and long-term survival outcomes. However, MIS is relatively infrequentl ... Full text Cite

Delayed presentation of urethrocutaneous fistulae after hypospadias repair.

Journal Article J Pediatr Surg · October 2020 BACKGROUND: Delayed urethrocutaneous fistula (UCF) presentation after hypospadias repair is rarely reported. The aim of this study is to report our experience with delayed UCF presenting more than 5 years after hypospadias repair. METHODS: We conducted a r ... Full text Open Access Link to item Cite

Relationship between tumor response at therapy completion and prognosis in patients with Group III rhabdomyosarcoma: A report from the Children's Oncology Group.

Conference Int J Cancer · September 1, 2020 A subset of patients with initially unresected (Clinical Group III) rhabdomyosarcoma achieve less than a complete response (CR) despite multimodal therapy. We assessed outcome based upon tumor response at the completion of all planned therapy. We studied 6 ... Full text Link to item Cite

Kidney Function Surveillance in the National Spina Bifida Patient Registry: A Retrospective Cohort Study.

Journal Article J Urol · September 2020 PURPOSE: Chronic kidney disease affects 25% to 50% of patients with spina bifida. Guidelines recommend kidney function surveillance in these patients but practice patterns are unknown. Variations in kidney function surveillance were assessed in patients wi ... Full text Link to item Cite

A survey and panel discussion of the effects of the COVID-19 pandemic on paediatric urological productivity, guideline adherence and provider stress.

Journal Article J Pediatr Urol · August 2020 INTRODUCTION: The COVID-19 pandemic has led to an unprecedented need to re-organise and re-align priorities for all surgical specialties. Despite the current declining numbers globally, the direct effects of the pandemic on institutional practices and on p ... Full text Open Access Link to item Cite

Community perspectives on difference of sex development (DSD) diagnoses: A crowdsourced survey.

Journal Article J Pediatr Urol · June 2020 INTRODUCTION AND OBJECTIVES: Differences of sex development (DSD) engender ethical, social and psychosexual complexities that can complicate medical decision-making. We performed a web-based pilot study to estimate the utility value of a DSD diagnosis and ... Full text Link to item Cite

Patterns of inpatient care for prostate cancer in men with spina bifida.

Journal Article Disabil Health J · April 2020 BACKGROUND: Advances in medical care have increased the long-term survival of patients with spina bifida. Despite this growing population, limited knowledge is available on age-related illnesses in adults with spina bifida, particularly prostate cancer for ... Full text Open Access Link to item Cite

Philosophy of care delivery for spina bifida.

Journal Article Disabil Health J · April 2020 The multidisciplinary model (MCM) is described as one that utilizes skills and experience from practitioners belonging to various disciplines, each treating patients from a specific clinical perspective.1 The Spina Bifida Association (SBA) supports and rec ... Full text Link to item Cite

In Reply.

Other Oncologist · April 2020 This letter to the editor responds to recent comments by Strohbehn and Daugherty in Mistaking the Trees for the Forest. ... Full text Link to item Cite

Bone scan positivity in non-metastatic, castrate-resistant prostate cancer: external validation study.

Journal Article Int Braz J Urol · 2020 INTRODUCTION: Tables predicting the probability of a positive bone scan in men with non-metastatic, castrate-resistant prostate cancer have recently been reported. We performed an external validation study of these bone scan positivity tables. MATERIALS AN ... Full text Open Access Link to item Cite

Neurogenic bowel treatments and continence outcomes in children and adults with myelomeningocele.

Journal Article J Pediatr Rehabil Med · 2020 PURPOSE: Neurogenic bowel dysfunction (NBD) is a common comorbidity of myelomeningocele (MMC), the most common and severe form of spina bifida. The National Spina Bifida Patient Registry (NSBPR) is a research collaboration between the CDC and Spina Bifida ... Full text Link to item Cite

Partial and radical nephrectomy in children, adolescents, and young adults: Equivalent readmissions and postoperative complications.

Journal Article J Pediatr Surg · November 2019 OBJECTIVES: To compare and contrast the use of partial nephrectomy (PN) and radical nephrectomy (RN) in pediatric malignant renal tumors using a nationally representative database. METHODS: The 2010-2014 Nationwide Readmissions Database (NRD) was used to o ... Full text Link to item Cite

Immune expression in children with Wilms tumor: a pilot study.

Journal Article J Pediatr Urol · October 2019 BACKGROUND: Given improvements in multimodality therapy, survival among children with Wilms tumor (WT) exceeds 90%. However, 15% of children with favorable histology and 50% of children with anaplastic WT experience recurrence or progression. Of patients w ... Full text Link to item Cite

National Imaging and Antibiotic Practice Patterns in Children Presenting With Urinary Tract Infection to Community Practices: Little Impact From the American Academy of Pediatrics Guidelines?

Journal Article Clin Pediatr (Phila) · October 2019 Our objective was to use community-based, national databases to evaluate diagnostic imaging and antibiotic prophylaxis practice patterns before and after the release of the 2011 American Academy of Pediatrics guidelines for acute febrile urinary tract infe ... Full text Link to item Cite

Increased local failure for patients with intermediate-risk rhabdomyosarcoma on ARST0531: A report from the Children's Oncology Group.

Journal Article Cancer · September 15, 2019 BACKGROUND: The objective of this study was to evaluate local control for patients with intermediate-risk rhabdomyosarcoma (RMS) treated on Children's Oncology Group (COG) protocol ARST0531. METHODS: This study analyzed 424 patients with intermediate-risk ... Full text Link to item Cite

Outcomes of Bladder Preservation Following Treatment for Rhabdomyosarcoma

Journal Article Current Bladder Dysfunction Reports · September 15, 2019 Purpose of Review: Genitourinary rhabdomyosarcoma (RMS) is a relatively uncommon pediatric urologic oncologic condition with significant implications for both short- and long-term bladder functions. It is important for both pediatric and adult urologists t ... Full text Cite

Nationwide Readmission Rates Following Percutaneous Nephrolithotomy: Does Age Matter?

Journal Article J Endourol · September 2019 Introduction/Objectives: Despite minimal evidence that evaluates the effect of age on percutaneous nephrolithotomy (PCNL) morbidity, pediatric and elderly patients are considered high-risk groups. Our objective was to assess the effect of the extremes of a ... Full text Link to item Cite

Editorial Comment.

Journal Article J Urol · August 2019 Full text Link to item Cite

Hospital and ED charges for spina bifida care in the United States between 2006 and 2014: Over $2 billion annually.

Journal Article Disabil Health J · July 2019 BACKGROUND: More children with spina bifida (SB) are surviving into adulthood. Unfortunately, little data exist regarding the economic implications of modern SB care. OBJECTIVE: We examined economic data from two national databases to estimate the annual n ... Full text Link to item Cite

Baseline Urinary Tract Imaging in Infants Enrolled in the UMPIRE Protocol for Children with Spina Bifida.

Journal Article J Urol · June 2019 PURPOSE: The lifetime risk of renal damage in children with spina bifida is high but only limited baseline imaging data are available for this population. We evaluated a large prospective cohort of infants with spina bifida to define their baseline imaging ... Full text Link to item Cite

Parental Preferences for Vesicoureteral Reflux Treatment: A Crowd-sourced, Best-worst Scaling Study.

Journal Article Urology · June 2019 OBJECTIVE: To quantitatively evaluate parental preferences for the various treatments for vesicoureteral reflux using crowd-sourced best-worst scaling, a novel technique in urologic preference estimation. METHODS: Preference data were collected from a comm ... Full text Open Access Link to item Cite

National estimations of airway foreign bodies in children in the United States, 2000 to 2009.

Journal Article Clin Otolaryngol · May 2019 OBJECTIVE: Identify risk factors associated with airway foreign bodies in children in the United States and report observed trends over time. DATA SOURCE: KID database (2000-2009). METHODS: ICD-9-CM codes for airway foreign bodies were used to identify pat ... Full text Link to item Cite

Early Impact of the Patient Protection and Affordable Care Act on Delivery of Children's Surgical Care.

Journal Article Clin Pediatr (Phila) · April 2019 The impact of the Patient Protection and Affordable Care Act (PPACA) on children's access to surgical care is not well-defined. Our objective was to describe the early impact of PPACA on children's surgical care before and after Medicaid expansion in 2014. ... Full text Link to item Cite

Discrepancies in Self-Reported and Actual Conflicts of Interest for Robotic Pediatric Urological Surgery.

Journal Article J Urol · February 2019 PURPOSE: Transparency of conflicts of interest is essential when assessing publications that address the benefits of robotic surgery over traditional laparoscopic and open operations. We assessed discrepancies between self-reported and actual conflicts of ... Full text Link to item Cite

NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation.

Journal Article Diabetes · February 2019 The NLRP3 inflammasome senses diabetic metabolites and initiates inflammation implicated in diabetic complications and neurodegeneration. No studies have investigated NLRP3 in diabetic bladder dysfunction (DBD), despite a high clinical prevalence. In vitro ... Full text Link to item Cite

Assessment of pediatric bowel and bladder dysfunction: a critical appraisal of the literature.

Journal Article J Pediatr Urol · December 2018 OBJECTIVE: Bowel and bladder dysfunction (BBD) is a clinical syndrome defined by the coexistence of constipation and lower urinary tract symptoms. Although BBD is a common condition in pediatric urology and can cause significant stress to patients/parents, ... Full text Link to item Cite

Wilms Tumor After Orthotopic Liver Transplant in a Patient With Alagille Syndrome.

Journal Article Urology · November 2018 We present a case of Wilms Tumor in a patient with Alagille syndrome 10 months after liver transplant. We explore a suggested genetic connection between these 2 diseases. In children with Wilms Tumor, we propose a pathoembryologic explanation for not just ... Full text Link to item Cite

Lower Urinary Tract Symptoms in Older Children With and Without Diabetes Mellitus.

Journal Article Clin Pediatr (Phila) · November 2018 Lower urinary tract symptoms (LUTS) are an underrecognized complication of diabetes mellitus (DM) in adults and have undergone limited investigation in children. We estimated the prevalence of LUTS in 120 older children (11-17 years) with and without DM an ... Full text Link to item Cite

How to close classic bladder exstrophy: Are subspecialty training and technique important?

Journal Article J Pediatr Urol · October 2018 INTRODUCTION: Successful primary closure is one of the main factors for achieving continence in a classic bladder exstrophy (CBE) patient. Even with contemporary management, patients still have failed primary closures. We sought to understand the role of t ... Full text Link to item Cite

Predominant bacteria and patterns of antibiotic susceptibility in urinary tract infection in children with spina bifida.

Journal Article J Pediatr Urol · October 2018 BACKGROUND: Urinary tract infection is more common in children with spina bifida (SB) than neurologically intact children, and Escherichia coli is the most common urinary pathogen in the general pediatric population. Less is known of the pathogens responsi ... Full text Link to item Cite

Disproportionate Use of Inpatient Care by Older Adults With Kidney Stones.

Journal Article Urology · October 2018 OBJECTIVE: To describe variation in utilization and costs of inpatient care for patients with kidney stones, examining associations with older age. MATERIALS AND METHODS: Using the Nationwide Inpatient Sample we examined inpatient discharges with stone dia ... Full text Link to item Cite

Analgesic Prescribing Patterns for Acute Symptomatic Kidney Stones in Emergency Departments

Conference Journal of the American College of Surgeons · October 2018 Full text Cite

Bladder Management and Continence Outcomes in Adults with Spina Bifida: Results from the National Spina Bifida Patient Registry, 2009 to 2015.

Journal Article J Urol · July 2018 PURPOSE: Most children with spina bifida now survive into adulthood, although most have neuropathic bladder with potential complications of incontinence, infection, renal damage and diminished quality of life. In this study we sought to 1) describe contemp ... Full text Link to item Cite

The evaluation of three comorbidity indices in predicting postoperative complications and readmissions in pediatric urology.

Journal Article J Pediatr Urol · June 2018 INTRODUCTION: The surgical comorbidity assessment is important for patient risk stratification, counseling, and research. In adults, risk assessment indices, such as the Charlson Co-morbidity Score (CCS) or Van Walraven Index (VWI), are well established. I ... Full text Link to item Cite

Interrater Reliability in Interpretation of Neuropathic Pediatric Urodynamic Tracings: An Expanded Multicenter Study.

Journal Article J Urol · May 2018 PURPOSE: Urodynamic findings often guide treatment for neuropathic bladder and are reported as objective data points in multi-institutional trials. However, urodynamic interpretation can be variable. In a pilot study pediatric urologists interpreting video ... Full text Link to item Cite

National Characteristics of Lymphatic Malformations in Children: Inpatient Estimates and Trends in the United States, 2000 to 2009.

Journal Article J Pediatr Hematol Oncol · April 2018 With ever increasing demands to manage finite resources for health care utilization, we performed an investigation to identify inpatient clinical characteristics and trends in children with lymphatic malformations using the Kids' Inpatient Database, years ... Full text Link to item Cite

Contemporary Demographic, Treatment, and Geographic Distribution Patterns for Disorders of Sex Development.

Journal Article Clin Pediatr (Phila) · March 2018 This study aimed to describe the demographic characteristics, hospital utilizations, patterns of inpatient surgical management, and the overall state/regional variation in surgery rate among patients with disorders of sex development (DSD). We analyzed the ... Full text Link to item Cite

Longitudinal Study of Bladder Continence in Patients with Spina Bifida in the National Spina Bifida Patient Registry.

Journal Article J Urol · March 2018 PURPOSE: Achieving bladder continence in individuals with spina bifida is a lifetime management goal. We investigated bladder continence status through time and factors associated with this status in patients with spina bifida. MATERIALS AND METHODS: We us ... Full text Link to item Cite

Comparing oncologic outcomes after minimally invasive and open surgery for pediatric neuroblastoma and Wilms tumor.

Journal Article Pediatr Blood Cancer · January 2018 BACKGROUND: Minimally invasive surgery (MIS) has been widely adopted for common operations in pediatric surgery; however, its role in childhood tumors is limited by concerns about oncologic outcomes. We compared open and MIS approaches for pediatric neurob ... Full text Link to item Cite

Bladder Reconstruction Rates Differ among Centers Participating in National Spina Bifida Patient Registry.

Journal Article J Urol · January 2018 PURPOSE: We performed an exploratory analysis of data from the NSBPR (National Spina Bifida Patient Registry) to assess variation in the frequency of bladder reconstruction surgeries among NSBPR centers. MATERIALS AND METHODS: We queried the 2009-2014 NSBP ... Full text Link to item Cite

Diabetic bladder dysfunction is associated with bladder inflammation triggered through hyperglycemia, not polyuria.

Journal Article Res Rep Urol · 2018 PURPOSE: Diabetes is a grave and progressive condition characterized by debilitating complications. Diabetic bladder dysfunction (DBD) is a very common complication with no specific treatments currently available. Unlike other tissues affected by this dise ... Full text Open Access Link to item Cite

Bowel management and continence in adults with spina bifida: Results from the National Spina Bifida Patient Registry 2009-15.

Journal Article J Pediatr Rehabil Med · December 11, 2017 INTRODUCTION: Advances in care have allowed most children with spina bifida (SB) to live to adulthood. The majority have neuropathic bowel dysfunction (NBD), resulting in constipation, incontinence, and diminished quality of life. We sought to 1) describe ... Full text Link to item Cite

Evaluation of spina bifida transitional care practices in the United States.

Journal Article J Pediatr Rehabil Med · December 11, 2017 PURPOSE: Recent studies have revealed that the lack of continuity in preparing patients with spina bifida to transition into adult-centered care may have detrimental health consequences. We sought to describe current practices of transitional care services ... Full text Link to item Cite

Variation in surgical management of neurogenic bowel among centers participating in National Spina Bifida Patient Registry.

Journal Article J Pediatr Rehabil Med · December 11, 2017 PURPOSE: Optimal management of neurogenic bowel in patients with spina bifida (SB) remains controversial. Surgical interventions may be utilized to treat constipation and provide fecal continence, but their use may vary among SB treatment centers. METHODS: ... Full text Link to item Cite

Crowdsourcing utility estimation for spina bifida in the general population.

Journal Article J Pediatr Rehabil Med · December 11, 2017 INTRODUCTION: Cost-utility analyses (CUA) are useful when the treatment conditions depend on patient preferences that are in turn dependent on health state utility value. Spina bifida (SB) is an example of such a preference-sensitive condition. Historicall ... Full text Link to item Cite

Editorial Comment.

Journal Article J Urol · December 2017 Full text Link to item Cite

Renal medullary carcinoma: A national analysis of 159 patients.

Journal Article Pediatr Blood Cancer · November 2017 BACKGROUND: Renal medullary carcinoma (RMC) is an aggressive malignancy seen predominantly in young males with sickle cell trait. RMC is poorly understood, with fewer than 220 cases described in the medical literature to date. We used a large national regi ... Full text Link to item Cite

Epidemiologic Analysis of Elective Operative Procedures in Infants Less Than 6 Months of Age in the United States.

Journal Article Anesth Analg · November 2017 BACKGROUND: This study uses publicly available data to analyze the total number of elective, potentially deferrable operative procedures involving infants <6 months of age in the United States. We investigated the factors associated with the performance of ... Full text Link to item Cite

Readmissions, unplanned emergency room visits, and surgical retreatment rates after anti-reflux procedures.

Journal Article J Pediatr Urol · October 2017 INTRODUCTION/BACKGROUND: The choice between endoscopic injection (EI) and ureteroneocystotomy (UNC) for surgical correction of vesicoureteral reflux (VUR) is controversial. OBJECTIVE: To compare postoperative outcomes of EI vs UNC. STUDY DESIGN: This study ... Full text Link to item Cite

The Public Health Burden of Lymphatic Malformations in Children: National Estimates in the United States, 2000-2009.

Journal Article Lymphat Res Biol · September 2017 OBJECTIVE: Describe inpatient resource utilization trends in children with lymphatic malformations using a national database. DATA SOURCE: Kids' inpatient database, years 2000-2009. METHODS: Subjects included children 18 years and under with International ... Full text Link to item Cite

Yellow-Orange Penile Papules.

Journal Article Pediatr Dermatol · September 2017 Full text Link to item Cite

The association between caudal anesthesia and increased risk of postoperative surgical complications in boys undergoing hypospadias repair.

Journal Article Paediatr Anaesth · July 2017 INTRODUCTION: Recent reports have suggested that caudal anesthesia may be associated with an increased risk of postoperative surgical complications. We examined our experience with caudal anesthesia in hypospadias repair to evaluate for increased risk of u ... Full text Link to item Cite

Open versus minimally invasive surgical approaches in pediatric urology: Trends in utilization and complications.

Journal Article J Pediatr Urol · June 2017 OBJECTIVE: Minimally invasive surgery (MIS) techniques are anecdotally reported to be increasingly used, but little objective data supports this. Our objective was to assess trends in MIS utilization across various procedures in pediatric urology and to co ... Full text Link to item Cite

Patterns of Performance of Oncologic Surgery by North American Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology.

Journal Article J Urol · May 2017 PURPOSE: Objective data on patterns of oncology practice among pediatric urologists are lacking. We reviewed surgical case logs submitted to the American Board of Urology by those self-reporting as pediatric urologists. We hypothesized that logs would reve ... Full text Link to item Cite

The public health resource utilization impact of airway foreign bodies in children.

Journal Article Int J Pediatr Otorhinolaryngol · May 2017 OBJECTIVE: Quantify the resource utilization associated with airway foreign bodies in children in the United States using a national database and report observed trends over time. STUDY TYPE: Cross-sectional analysis of national inpatient database with wei ... Full text Link to item Cite

Diagnostic evaluation of ovarian torsion: An analysis of pediatric patients using the Nationwide Emergency Department Sample.

Journal Article Am J Surg · April 2017 BACKGROUND: Ultrasonography (US) is the diagnostic modality of choice during work-up for ovarian torsion, although computed tomography (CT) may be used. We examined the utilization of CT in girls with ovarian torsion, and determined which patients are most ... Full text Link to item Cite

Risk Factors Associated With Recurrent Urinary Tract Infection in Neurogenic Bladders Managed by Clean Intermittent Catheterization.

Journal Article Urology · April 2017 OBJECTIVE: To identify risk factors for recurrent urinary tract infection (UTI) in patients who perform clean intermittent catheterization (CIC). METHODS: A 6-year retrospective chart review of patients with spina bifida or tethered cord who perform clean ... Full text Link to item Cite

Utility Estimation for Pediatric Vesicoureteral Reflux: Methodological Considerations Using an Online Survey Platform.

Journal Article J Urol · March 2017 PURPOSE: The advent of online task distribution has opened a new avenue for efficiently gathering community perspectives needed for utility estimation. Methodological consensus for estimating pediatric utilities is lacking, with disagreement over whom to s ... Full text Link to item Cite

A Society for Pediatric Urology Workforce Survey on the Current Perceptions of Oncology Care by Pediatric Urologists: A Report from the Pediatric Urologic Oncology Working Group of the Society for Pediatric Urology.

Journal Article J Urol · March 2017 PURPOSE: Data are lacking on the current perception of oncology care among pediatric urologists. Thus, we developed, pilot tested and administered a survey on this topic to SPU (Society for Pediatric Urology) members. MATERIALS AND METHODS: Approval for th ... Full text Link to item Cite

Parental Preference Assessment for Vesicoureteral Reflux Management in Children.

Journal Article J Urol · March 2017 PURPOSE: Parents of children with vesicoureteral reflux are presented with a variety of management options, which in many cases offer a similar risk-benefit ratio. To facilitate shared decision making, parental preferences regarding vesicoureteral reflux t ... Full text Link to item Cite

Editorial Comment.

Other J Urol · March 2017 Full text Link to item Cite

Editorial Comment.

Other J Urol · March 2017 Full text Link to item Cite

A Nationwide Assessment of the Emergency Department Management of Acute Urinary Retention Due to Urethral Stricture.

Journal Article Urology · February 2017 OBJECTIVE: To evaluate the nationwide practice patterns of the management of acute urinary retention (AUR) secondary to urethral stricture (US) in an emergency department (ED) setting. MATERIALS AND METHODS: We used the 2006-2010 Nationwide Emergency Depar ... Full text Link to item Cite

Incidence of Breakthrough Urinary Tract Infection in Hospitalized Infants Receiving Antibiotic Prophylaxis.

Journal Article Clin Pediatr (Phila) · January 2017 Urinary tract infections (UTIs) are a source of substantial morbidity in children in the neonatal intensive care unit. The incidence of UTIs that occur in critically ill infants during a course of antibiotic prophylaxis (i.e., breakthrough urinary tract in ... Full text Link to item Cite

Increased pediatric sub-specialization is associated with decreased surgical complication rates for inpatient pediatric urology procedures.

Journal Article J Pediatr Urol · December 2016 INTRODUCTION: Increased case volumes and training are associated with better surgical outcomes. However, the impact of pediatric urology sub-specialization on perioperative complication rates is unknown. OBJECTIVES: To determine the presence and magnitude ... Full text Link to item Cite

Design and Methodological Considerations of the Centers for Disease Control and Prevention Urologic and Renal Protocol for the Newborn and Young Child with Spina Bifida.

Journal Article J Urol · December 2016 PURPOSE: Care of children with spina bifida has significantly advanced in the last half century, resulting in gains in longevity and quality of life for affected children and caregivers. Bladder dysfunction is the norm in patients with spina bifida and may ... Full text Link to item Cite

Biomarkers for Wilms Tumor: A Systematic Review.

Journal Article J Urol · November 2016 PURPOSE: Wilms tumor is the most common childhood renal malignancy and the fourth most common childhood cancer. Many biomarkers have been studied but there has been no comprehensive summary. We systematically reviewed the literature on biomarkers in Wilms ... Full text Link to item Cite

Open versus minimally invasive ureteroneocystostomy: A population-level analysis.

Journal Article J Pediatr Urol · August 2016 INTRODUCTION: Open ureteroneocystostomy (UNC) is the gold standard for surgical correction of vesicoureteral reflux (VUR). Beyond single-center reports, there are few published data on outcomes of minimally-invasive (MIS) UNC. Our objective was to compare ... Full text Link to item Cite

Is the Economic Impact and Utilization of Imaging Studies for Pediatric Urolithiasis Across the United States Increasing?

Journal Article Urology · August 2016 OBJECTIVE: To identify longitudinal trends of economic impact and resource utilization for management of pediatric urolithiasis using national databases. METHODS: We analyzed the 2006-2012 Nationwide Emergency Department Sample and Nationwide Inpatient Sam ... Full text Link to item Cite

Outcomes of Shock Wave Lithotripsy and Ureteroscopy for Treatment of Pediatric Urolithiasis.

Journal Article J Urol · July 2016 PURPOSE: Shock wave lithotripsy has been commonly used to treat children with renal and ureteral calculi but recently ureteroscopy has been used more frequently. We examined postoperative outcomes from these 2 modalities in children. MATERIALS AND METHODS: ... Full text Link to item Cite

Nationwide Trends and Variations in Urological Surgical Interventions and Renal Outcome in Patients with Spina Bifida.

Journal Article J Urol · April 2016 PURPOSE: Bladder dysfunction in patients with spina bifida can lead to significant morbidity due to renal insufficiency. Indications for surgery vary among institutions and the impact is unclear. We examined trends and variations in urological intervention ... Full text Link to item Cite

Trends in Sickle Cell Disease-related Priapism in U.S. Children's Hospitals.

Journal Article Urology · March 2016 OBJECTIVE: To define rates of priapism diagnosis and inpatient admission among males with sickle cell disease (SCD). PATIENTS AND METHODS: We retrospectively reviewed the Pediatric Health Information System database for males aged <21 years treated 2004-20 ... Full text Link to item Cite

Rare variants in tenascin genes in a cohort of children with primary vesicoureteric reflux.

Journal Article Pediatr Nephrol · February 2016 BACKGROUND: Primary vesicoureteral reflux (PVUR) is the most common malformation of the kidney and urinary tract, and reflux nephropathy is a major cause of chronic kidney disease in children. Recently, we reported mutations in the tenascin XB gene (TNXB) ... Full text Link to item Cite

Nephron-sparing surgery for Wilms tumor: A systematic review.

Journal Article Urol Oncol · January 2016 INTRODUCTION: Radical nephrectomy (RN, or total nephrectomy) is the current gold-standard surgical treatment for children with Wilms tumors (WT). However, nephron-sparing surgery (NSS, or partial nephrectomy) has recently been gaining increasing attention. ... Full text Link to item Cite

High Flow Priapism in a Pediatric Patient after Circumcision with Dorsal Penile Nerve Block.

Journal Article Case Rep Pediatr · 2016 We report the first documented case of high flow priapism after circumcision with dorsal penile nerve block. A 7-year-old male who had undergone circumcision three years before presented to our institution with a 3-year history of persistent nonpainful ere ... Full text Open Access Link to item Cite

Medical expulsive therapy for pediatric urolithiasis: Systematic review and meta-analysis.

Journal Article J Pediatr Urol · December 2015 OBJECTIVE: Kidney stone disease has become more common among children and young adults. Despite its well-documented success in adults, published success rates of medical expulsive therapy (MET) for pediatric urolithiasis vary widely. Our objective was to d ... Full text Link to item Cite

Use of patient registries and administrative datasets for the study of pediatric cancer.

Journal Article Pediatr Blood Cancer · September 2015 Analysis of data from large administrative databases and patient registries is increasingly being used to study childhood cancer care, although the value of these data sources remains unclear to many clinicians. Interpretation of large databases requires a ... Full text Link to item Cite

Hospital Surgical Volume and Associated Postoperative Complications of Pediatric Urological Surgery in the United States.

Journal Article J Urol · August 2015 PURPOSE: Hospital and provider surgical volume have been increasingly linked to surgical outcomes. However, this topic has rarely been addressed in children. We investigated whether hospital surgical volume impacts complication rates in pediatric urology. ... Full text Link to item Cite

Utility scores for vesicoureteral reflux and anti-reflux surgery.

Journal Article J Pediatr Urol · August 2015 BACKGROUND: Management of vesicoureteral reflux (VUR) continues to be controversial. In conditions of uncertainty, decision analytic techniques such as cost-utility analysis (CUA) can help to structure the decision-making process. However, CUA analyses req ... Full text Link to item Cite

Estimating the nationwide, hospital based economic impact of pediatric urolithiasis.

Journal Article J Urol · May 2015 PURPOSE: The incidence of urolithiasis is increasing in children and adolescents but the economic impact of this problem is unclear. We examined 2 large databases to estimate the nationwide economic impact of pediatric urolithiasis. MATERIALS AND METHODS: ... Full text Link to item Cite

Editorial comment.

Other Urology · May 2015 Full text Link to item Cite

Emergent care patterns in patients with spina bifida: a case-control study.

Journal Article J Urol · January 2015 PURPOSE: Individuals with spina bifida are typically followed closely as outpatients by multidisciplinary teams. However, emergent care of these patients is not well defined. We describe patterns of emergent care in patients with spina bifida and healthy c ... Full text Link to item Cite

Editorial comment.

Other Urology · January 2015 Full text Link to item Cite

Editorial comment.

Other Urology · July 2014 Full text Link to item Cite

Trends in revision circumcision at pediatric hospitals.

Journal Article Clin Pediatr (Phila) · August 2013 BACKGROUND: We sought to determine the incidence of revision circumcision at freestanding children's hospitals, and examine trends over time. METHODS: We searched the Pediatric Health Information Systems database to identify boys undergoing revision circum ... Full text Link to item Cite

Variation in definitions of urinary tract infections in spina bifida patients: a systematic review.

Journal Article Pediatrics · July 2013 OBJECTIVE: Urinary tract infections (UTIs) are a common source of morbidity among children with spina bifida (SB) and are a frequently reported outcome in studies of this patient population. However, the criteria for a diagnosis of UTI are often not stated ... Full text Link to item Cite

Urological complications and vesicoureteral reflux following pediatric kidney transplantation.

Journal Article J Urol · March 2013 PURPOSE: Ureteral complications of renal transplantation can dramatically impact renal outcomes. We studied whether complications are associated with preexisting genitourinary pathology or transplant using a deceased donor allograft. MATERIALS AND METHODS: ... Full text Link to item Cite

Editorial comment.

Other J Urol · February 2013 Full text Link to item Cite

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Other Urology · February 1, 2013 Full text Cite

Quality assessment of economic analyses in pediatric urology.

Journal Article Urology · February 2013 OBJECTIVE: To describe and evaluate economic analyses or economic evaluations in pediatric urologic literature, including study types such as cost-effectiveness analysis, which are increasingly common in the medical literature. METHODS: We performed a syst ... Full text Link to item Cite

Partial orchiectomy for bilateral synchronous testicular masses in a prepubescent boy: a case report.

Journal Article Urology · November 2012 Testicular masses in prepubescent children are typically benign. Most masses are mature teratomas, epidermoid cysts, and stromal tumors. Synchronous bilateral testicular masses in children are rare. The etiology of these includes synchronous primary testic ... Full text Link to item Cite

How dry is dry? A review of definitions of continence in the contemporary exstrophy/epispadias literature.

Journal Article J Urol · November 2012 PURPOSE: Definitions of continence following surgery in children with exstrophy-epispadias complex vary widely. We assessed the most common definitions of continence and evaluated the clinical significance of usage patterns for those definitions. MATERIALS ... Full text Link to item Cite

Patient and family impact of pediatric genitourinary diagnostic imaging tests.

Journal Article J Urol · October 2012 PURPOSE: The impact of diagnostic genitourinary imaging on patients and families is poorly understood. We measured patient and family reaction to commonly performed genitourinary imaging studies using a standardized measurement tool. MATERIALS AND METHODS: ... Full text Link to item Cite

Association of urolithiasis with systemic conditions among pediatric patients at children's hospitals.

Journal Article J Urol · October 2012 PURPOSE: Urolithiasis is associated with systemic medical conditions in adults but associations have not been well studied in children. We investigated the association of urolithiasis with diabetes mellitus, hypertension and obesity among children with and ... Full text Link to item Cite

EFFECTS OF SODIUM AND FRUCTOSE INTAKE ON PEDIATRIC STONE FORMATION

Conference JOURNAL OF ENDOUROLOGY · September 1, 2012 Link to item Cite

Shock wave lithotripsy vs ureteroscopy: variation in surgical management of kidney stones at freestanding children's hospitals.

Journal Article J Urol · April 2012 Featured Publication PURPOSE: Although shock wave lithotripsy has long been considered the gold standard for treatment of kidney stones in children, ureteroscopy has become increasingly common. The factors determining procedure choice at individual centers are unclear. We soug ... Full text Link to item Cite

Vesicoureteral reflux: current trends in diagnosis, screening, and treatment.

Journal Article Eur Urol · April 2012 Featured Publication CONTEXT: Vesicoureteral reflux (VUR) is present in approximately 1% of children in North America and Europe and is associated with an increased risk of pyelonephritis and renal scarring. Despite its prevalence and potential morbidity, however, many aspects ... Full text Link to item Cite

Prospective measurement of patient exposure to radiation during pediatric ureteroscopy.

Journal Article J Urol · April 2012 Featured Publication PURPOSE: Few data have been reported regarding radiation exposure during pediatric endourological procedures, including ureteroscopy. We measured radiation exposure during pediatric ureteroscopy and identify opportunities for exposure reduction. MATERIALS ... Full text Link to item Cite

Economic and radiation costs of initial imaging approaches after a child's first febrile urinary tract infection.

Journal Article Clin Pediatr (Phila) · January 2012 Featured Publication BACKGROUND. The traditional initial imaging approach following pediatric urinary tract infection is the "bottom-up" approach (cystogram and renal ultrasound). Recently, the "top-down" approach (nuclear renal scan followed by cystogram for abnormal scans on ... Full text Link to item Cite

Racial variation in timing of pyeloplasty: prenatal versus postnatal diagnosis.

Journal Article J Urol · December 2011 Featured Publication PURPOSE: We have previously shown that nonwhite patients with ureteropelvic junction obstruction undergo pyeloplasty at a younger age than white patients. The mechanisms behind this finding are unclear, since there is no known racial variation in the natur ... Full text Link to item Cite

Vesicoureteral reflux in children with urachal anomalies.

Journal Article J Pediatr Urol · December 2011 Featured Publication OBJECTIVE: We report the largest known series of vesicoureteral reflux (VUR) in children with urachal anomalies (UA). METHODS: Two institutions' records were reviewed for children with UA (1951‒2007). RESULTS: Of 30 girls and 36 boys with UA (34 urachal cy ... Full text Link to item Cite

Does a controversial topic affect the quality of urologic information on the Internet?

Journal Article Urology · November 2011 OBJECTIVE: Increasingly, patients seek medical information via the Internet, despite highly variable information quality. We sought to determine whether controversial urological topics are associated with decreased content quality or search characteristics ... Full text Link to item Cite

Screening for malignancy after augmentation cystoplasty in children with spina bifida: a decision analysis.

Journal Article J Urol · October 2011 Featured Publication PURPOSE: Augmentation cystoplasty is the mainstay of surgical treatment for medically refractory neurogenic bladder in patients with spina bifida. Concerns regarding an increased risk of malignancy have prompted many centers to consider routine postoperati ... Full text Link to item Cite

Use of the ureteral access sheath during ureteroscopy in children.

Journal Article J Urol · October 2011 Featured Publication PURPOSE: The use of ureteral access sheaths during ureteroscopy is common but there are sparse data on the safety and outcomes of ureteral access sheath use in children. We compared the outcomes of ureteroscopy with vs without a ureteral access sheath in c ... Full text Link to item Cite

Editor's comment.

Other Indian J Plast Surg · September 2011 Link to item Cite

Evaluation of the United States pediatric urology workforce and fellowships: a series of surveys performed in 2006-2010.

Journal Article J Pediatr Urol · August 2011 Featured Publication OBJECTIVE: In the US, there has been an evolution in the practice of pediatric urology from a primary academic sub-specialty focused on reconstruction of major congenital genitorurinary abnormalities to a mixed academic and private practice that serves as ... Full text Link to item Cite

Contemporary use of nephron-sparing surgery for children with malignant renal tumors at freestanding children's hospitals.

Journal Article Urology · August 2011 Featured Publication OBJECTIVE: It is widely accepted that, when feasible, nephron-sparing surgery (NSS) is preferable to radical nephrectomy (RN) for treatment of renal tumors in adults. However, RN is more frequently used in children. We sought to compare in-hospital outcome ... Full text Link to item Cite

Editorial comment.

Other Urology · July 2011 Full text Link to item Cite

The gatekeeper disparity--why do some medical schools send more medical students into urology?

Journal Article J Urol · February 2011 PURPOSE: Urology continues to be a highly desirable specialty despite decreasing exposure of students to urology in American medical schools. We assessed how American medical schools compare to each other in regard to the number of students that each sends ... Full text Link to item Cite

Editorial comment.

Other Urology · January 2011 Full text Link to item Cite

Costs and consequences of universal sibling screening for vesicoureteral reflux: decision analysis.

Journal Article Pediatrics · November 2010 Featured Publication OBJECTIVE: Our objective was to evaluate screening for vesicoureteral reflux (VUR) among siblings of patients with VUR, in terms of cost, radiation exposure, and number of febrile urinary tract infections (fUTIs) averted. METHODS: We constructed a Markov m ... Full text Link to item Cite

Management strategies for Mayer-Rokitansky-Kuster-Hauser related vaginal agenesis: a cost-effectiveness analysis.

Journal Article J Urol · November 2010 PURPOSE: The optimal method for neovagina creation in patients with vaginal agenesis is controversial. Progressive perineal dilation is a minimally invasive method with high success rates. However, the economic merits of progressive perineal dilation compa ... Full text Link to item Cite

Trends in imaging and surgical management of pediatric urolithiasis at American pediatric hospitals.

Journal Article J Urol · October 2010 Featured Publication PURPOSE: Little is known of current practice patterns for pediatric urolithiasis. We examined recent trends in imaging and surgical management. MATERIALS AND METHODS: The Pediatric Health Information System database is a national database collected at Amer ... Full text Link to item Cite

Predicting renal outcomes in children with anterior urethral valves: a systematic review.

Journal Article J Urol · October 2010 Featured Publication PURPOSE: Prognostic information is limited on children with congenital anterior urethral valves or a diverticulum. We reviewed the literature and examined our clinical database to identify clinical features predicting a poor renal outcome, defined as azote ... Full text Link to item Cite

Epidemiological trends in pediatric urolithiasis at United States freestanding pediatric hospitals.

Journal Article J Urol · September 2010 Featured Publication PURPOSE: Anecdotal and lay press reports suggest that the incidence of pediatric urolithiasis is increasing but reliable data are lacking. The objective of this study was to examine trends in the epidemiology of urolithiasis at pediatric hospitals nationwi ... Full text Link to item Cite

Variations in timing of surgery among boys who underwent orchidopexy for cryptorchidism.

Journal Article Pediatrics · September 2010 Featured Publication OBJECTIVE: Current clinical guidelines recommend that orchidopexy be performed by the age of 1 in patients with congenital undescended testis. We sought to examine trends in surgical timing and to determine what factors are associated with age at surgery. ... Full text Link to item Cite

Editorial comment.

Other J Urol · August 2010 Full text Link to item Cite

Contemporary epidemiology and characterization of newborn males with prune belly syndrome.

Journal Article Urology · July 2010 Featured Publication OBJECTIVES: Prune belly syndrome (PBS) is a rare condition characterized by the congenital absence or deficiency of the abdominal wall musculature, with associated abnormalities of the genitourinary tract, including hydronephrosis and cryptorchidism. Few p ... Full text Link to item Cite

Predicting success in the endoscopic management of pediatric vesicoureteral reflux.

Journal Article Urology · July 2010 Featured Publication Vesicoureteral reflux is a common cause of pediatric morbidity. Though traditionally managed using a limited number of therapeutic modalities, the last decade has witnessed countless surgical innovations for treating reflux. A major force behind this innov ... Full text Link to item Cite

Ketorolac is underutilized after ureteral reimplantation despite reduced hospital cost and reduced length of stay.

Journal Article Urology · July 2010 OBJECTIVES: To examine patterns of ketorolac use and its association with hospital outcomes. Although ureteral reimplantation (UR) reliably corrects vesicoureteral reflux, postoperative pain and bladder spasm often occur. Multiple studies show that ketorol ... Full text Link to item Cite

Dextranomer/hyaluronic acid for pediatric vesicoureteral reflux: systematic review.

Journal Article Pediatrics · May 2010 Featured Publication OBJECTIVE: Published success rates of dextranomer/hyaluronic acid (Dx/HA) injection for pediatric vesicoureteral reflux (VUR) vary widely. Our objective of this study was to assess whether underlying patient or study factors could explain the heterogeneity ... Full text Link to item Cite

Regional variations in small intestinal submucosa evoke differences in inflammation with subsequent impact on tissue regeneration in the rat bladder augmentation model.

Journal Article BJU Int · May 2010 OBJECTIVE: To examine the histological differences in the inflammatory response and regenerative outcomes of distal vs proximal porcine small intestinal submucosa (SIS) grafts in the rat bladder, as SIS from distal small intestine yields reliable and repro ... Full text Link to item Cite

Variation among internet based calculators in predicting spontaneous resolution of vesicoureteral reflux.

Journal Article J Urol · April 2010 PURPOSE: An increasing number of parents and practitioners use the Internet for health related purposes, and an increasing number of models are available on the Internet for predicting spontaneous resolution rates for children with vesicoureteral reflux. W ... Full text Link to item Cite

Variation in surgical management of vesicoureteral reflux: influence of hospital and patient factors.

Journal Article Pediatrics · March 2010 Featured Publication OBJECTIVE: Controversy exists over surgical procedure choice for vesicoureteral reflux (VUR) in children. Either ureteral reimplantation (UR) or a newer procedure, endoscopic injection (EI), may be chosen; however, the factors that determine procedure choi ... Full text Link to item Cite

Editorial comment.

Other J Urol · February 2010 Full text Link to item Cite

Leukocyte inflammatory response in a rat urinary bladder regeneration model using porcine small intestinal submucosa scaffold.

Journal Article Tissue Eng Part A · November 2009 Small intestinal submucosa (SIS) is a biodegradable scaffold that supports bladder regeneration after partial cystectomy. We sought to define the inflammatory response present in a rat bladder augmentation model using distal ileal SIS. Fifteen Sprague-Dawl ... Full text Link to item Cite

Renal scarring and urinary tract infection after successful endoscopic correction of vesicoureteral reflux.

Journal Article J Urol · October 2009 PURPOSE: We evaluated renal function and the incidence of urinary tract infection after successful endoscopic correction of vesicoureteral reflux. MATERIALS AND METHODS: From 1988 to 2007, 169 male and 338 female patients (696 refluxing renal units) with a ... Full text Link to item Cite

Editorial comment.

Other J Urol · October 2009 Full text Link to item Cite

Pediatric urology and the internet--does an uncommon topic decrease content quality?

Journal Article J Urol · October 2009 PURPOSE: The Internet has become a widely used resource for patients and families to obtain medical information but the quality of information available is highly variable. We sought to determine if Web pages addressing common and uncommon pediatric urolog ... Full text Link to item Cite

Nonoperative management of nonvascular grade IV blunt renal trauma in children: meta-analysis and systematic review.

Journal Article Urology · September 2009 Featured Publication OBJECTIVES: To evaluate nonoperative management of grade IV blunt renal trauma in pediatric patients by performing a systematic review and meta-analysis of published studies. METHODS: MEDLINE, EMBASE, Cochrane, and Scopus databases were searched between Ja ... Full text Link to item Cite

Increasing prevalence and associated risk factors for methicillin resistant Staphylococcus aureus bacteriuria.

Journal Article J Urol · April 2009 PURPOSE: Infections due to methicillin resistant Staphylococcus aureus are becoming increasingly prevalent in hospitals and in the community. We reviewed our institutional experience to determine whether methicillin resistant S. aureus is becoming a more c ... Full text Link to item Cite

Minimal contamination of the human peritoneum after transvesical incision.

Journal Article J Endourol · April 2009 BACKGROUND AND PURPOSE: The recent literature has questioned the infectious risk of natural orifice translumenal endoscopic surgery (NOTES). The need for a clean portal of entry may be important to minimize peritoneal contamination after NOTES. Our study e ... Full text Link to item Cite

Sacral neuromodulation in children with dysfunctional elimination syndrome: description of incisionless first stage and second stage without fluoroscopy.

Journal Article Urology · March 2009 Featured Publication OBJECTIVES: To detail a percutaneous technique of sacral nerve neuromodulation (SN) that eliminates the first-stage incisions and the need for second-stage fluoroscopy. Our group has previously described the results of SN in children with medically refract ... Full text Link to item Cite

Iatrogenic ureteral injury: can adult repair techniques be used on children?

Journal Article J Pediatr Urol · February 2009 Featured Publication OBJECTIVE: Iatrogenic ureteral injury in children is a rare occurrence, with sparse literature available regarding optimal repair techniques. We reviewed our experience in the management of iatrogenic pediatric ureteral injuries, particularly with respect ... Full text Link to item Cite

Superficial genitourinary abscesses in children: emergence of methicillin resistant Staphylococcus aureus.

Journal Article J Urol · October 2008 Featured Publication PURPOSE: The prevalence of methicillin resistant Staphylococcus aureus is increasing. However, little is known about methicillin resistant S. aureus in the genitourinary tract, particularly in children. We assessed the incidence of pediatric genitourinary ... Full text Link to item Cite

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Other Journal of Urology · October 1, 2008 Full text Cite

Editorial Comment

Other Journal of Urology · October 1, 2008 Full text Cite

Unilateral vesicoureteral reflux: does endoscopic injection based on the cystoscopic appearance of the ureteral orifice decrease the incidence of de-novo contralateral reflux?

Journal Article J Pediatr Urol · August 2008 Featured Publication OBJECTIVE: In patients with unilateral vesicoureteral reflux (VUR), it has been suggested that injection of a non-refluxing but cystoscopically abnormal contralateral ureteral orifice (UO) with dextranomer/hyaluronic acid (Dx/HA) should be performed to pre ... Full text Link to item Cite

How long is too long? The effect of the duration of anaesthesia on the incidence of non-urological complications after surgery.

Journal Article BJU Int · August 2008 OBJECTIVE: To examine the association between the duration of anaesthesia and non-urological complication (NUC) rates after surgery, as the increasing complexity of minimally invasive and laparoscopic procedures in urology has resulted in longer surgery an ... Full text Link to item Cite

Reassessing the diagnostic yield of saturation biopsy of the prostate.

Journal Article Eur Urol · May 2008 OBJECTIVE: Prostate biopsy remains the gold standard for detection of prostate cancer (PCa). This study was performed to determine whether saturation biopsy (>or= 24 cores) detects more prostate cancer than a standard 12-18 core office biopsy technique. ME ... Full text Link to item Cite

B7-H1 expression in Wilms tumor: correlation with tumor biology and disease recurrence.

Journal Article J Urol · May 2008 PURPOSE: Despite tremendous gains in improving prognosis, 10% of patients with Wilms tumor will ultimately experience disease recurrence. The identification of novel prognostic markers and tumor associated targets for patients at risk could enable clinicia ... Full text Link to item Cite

Utility of dextranomer/hyaluronic acid injection in setting of bladder and ureteral anomalies.

Journal Article Urology · March 2008 OBJECTIVES: Previous studies have shown that the cure rates after dextranomer/hyaluronic acid (Dx/HA) injection can be decreased in patients with neurogenic bladder, previous ureteroneocystostomy, duplicated ureters, or periureteral diverticula. We attempt ... Full text Link to item Cite

Editorial Comment

Other Journal of Urology · January 1, 2008 Full text Cite

Preventing pain during office biopsy of the prostate: a single center, prospective, double-blind, 3-arm, parallel group, randomized clinical trial.

Journal Article Cancer · October 15, 2007 BACKGROUND: A prospective, double-blind, 3-arm, parallel group, randomized clinical trial was performed to compare 3 anesthetic techniques for preventing pain during prostate biopsy. METHODS: A total of 243 men undergoing a 12-core prostate biopsy were ran ... Full text Link to item Cite

Multivariate comparison of the efficacy of intraureteral versus subtrigonal techniques of dextranomer/hyaluronic acid injection.

Journal Article J Urol · October 2007 PURPOSE: Numerous factors have been postulated to increase success rates for dextranomer/hyaluronic acid injection for vesicoureteral reflux. Ureteral hydrodistention combined with intraureteral injection reportedly improves injection success rates. We com ... Full text Link to item Cite

Traumatic obliterative urethral strictures in pediatric patients: failure of the cut to light technique at long-term followup.

Journal Article J Urol · October 2007 Featured Publication PURPOSE: The cut to light procedure or antegrade and retrograde urethroscopy with endoscopic incision of obliterative urethral strictures is an accepted method of treating posterior urethral distraction injuries. We report long-term followup on 22 pediatri ... Full text Link to item Cite

Histopathological changes associated with dextranomer/hyaluronic acid injection for pediatric vesicoureteral reflux.

Journal Article J Urol · October 2007 Featured Publication PURPOSE: Few studies have examined the medium and long-term histological changes associated with periureteral injection of dextranomer/hyaluronic acid copolymer (Deflux(R)). We present the results of a histological review of a series of distal ureteral exc ... Full text Link to item Cite

Urachal anomalies: a longitudinal study of urachal remnants in children and adults.

Journal Article J Urol · October 2007 Featured Publication PURPOSE: Urachal anomalies are often recognized in children but they may persist into adulthood and cause considerable morbidity. We reviewed the clinical findings associated with these embryological structures and evaluated risk factors for cancer to defi ... Full text Link to item Cite

Long-term continence outcomes after immediate repair of pediatric bladder neck lacerations extending into the urethra.

Journal Article J Urol · October 2007 Featured Publication PURPOSE: Traumatic bladder neck lacerations extending into the urethra are devastating injuries that occur more commonly in children than in adults. It is unclear whether immediate repair of these injuries decreases long-term complications, such as urinary ... Full text Link to item Cite

Postoperative ureteral obstruction after subureteral injection of dextranomer/hyaluronic Acid copolymer.

Journal Article J Urol · October 2006 PURPOSE: Subureteral injection of dextranomer/hyaluronic acid copolymer is widely accepted for the treatment of primary vesicoureteral reflux. Few studies document the incidence of surgically relevant postoperative obstruction or the characteristics of pat ... Full text Link to item Cite

Tunneled tunica vaginalis flap is an effective technique for recurrent urethrocutaneous fistulas following tubularized incised plate urethroplasty.

Journal Article J Urol · October 2006 PURPOSE: In the last several years the use of the tubularized incised plate hypospadias repair has greatly increased. The most significant complication after this mode of urethroplasty is urethrocutaneous fistula development. Tunneled tunica vaginalis flap ... Full text Link to item Cite

Impact of Parkinson's disease on continence after radical prostatectomy.

Journal Article Urology · September 2006 OBJECTIVES: It is widely believed that men with idiopathic Parkinson's disease (PD) should not undergo prostate surgery because of the prohibitively high risk of incontinence. However, the data supporting this conclusion were based on cohorts undergoing pr ... Full text Link to item Cite

Single center experience with endoscopic management of vesicoureteral reflux in children.

Journal Article J Urol · May 2006 Featured Publication PURPOSE: Dx/HA copolymer was approved by the Food and Drug Administration in 2001 for the treatment of VUR in children. Published results have varied widely, prompting us to report our single center experience with 300 consecutive patients. MATERIALS AND M ... Full text Link to item Cite

Screening for Adenocarcinoma of the Prostate–Reply–I

Journal Article Mayo Clinic Proceedings · January 2006 Full text Cite

Adenocarcinoma of the prostate: epidemiological trends, screening, diagnosis, and surgical management of localized disease.

Journal Article Mayo Clin Proc · July 2005 Prostate cancer is a leading cause of mortality and morbidity worldwide. Despite years of study and effort, certain key questions remain unanswered, including how prostate cancer is best detected and diagnosed, how it is best treated, and how best to minim ... Full text Link to item Cite

Epididymo-orchitis and testicular abscess due to Nocardia asteroides complex.

Journal Article Urology · March 2005 Nocardia asteroides complex is a rare human pathogen chiefly affecting immunosuppressed patients. We present the sixth case of epididymo-orchitis attributable to this organism. A 78-year-old man presented to the Mayo Clinic with fever and weight loss after ... Full text Link to item Cite

Lactobacillus gasseri causing Fournier's gangrene.

Journal Article Scand J Infect Dis · 2004 Fournier's gangrene is characterized as an aggressive necrotizing process caused by a polymicrobial infection that includes virulent organisms. We report the first case of Fournier's gangrene caused by a low-virulence organism, Lactobacillus gasseri. ... Full text Link to item Cite

Six-year molecular analysis of Burkholderia cepacia complex isolates among cystic fibrosis patients at a referral center for lung transplantation.

Journal Article J Clin Microbiol · April 2002 Over a 6-year period, Burkholderia cepacia complex species were isolated from cystic fibrosis (CF) patients receiving care at The University of North Carolina Hospitals (clinic CF patients) and from those referred from other treatment centers. Fifty-six is ... Full text Link to item Cite

Lung transplantation for cystic fibrosis patients with Burkholderia cepacia complex. Survival linked to genomovar type.

Journal Article Am J Respir Crit Care Med · December 1, 2001 The number of cystic fibrosis (CF) patients undergoing lung transplant has risen over the past decade, because of a clear-cut survival benefit. However, patients with Burkholderia cepacia complex are often excluded from transplantation because of increased ... Full text Link to item Cite