Daniele Marin

Journal Article Int J Cancer · December 1, 2024 The purpose of this study was to determine if dual-energy CT (DECT) vital iodine tumor burden (ViTB), a direct assessment of tumor vascularity, allows reliable response assessment in patients with GIST compared to established CT criteria such as RECIST1.1 ... Full text Link to item Cite

Approaches, advantages, and challenges to photon counting detector and multi-energy CT.

Journal Article Abdom Radiol (NY) · September 2024 Photon counting detector CT (PCD-CT) is the newest major development in CT technology and has been commercially available since 2021. It offers major technological advantages over current standard-of-care energy integrating detector CT (EID-CT) including i ... Full text Link to item Cite

Photon-counting computed tomography versus energy-integrating computed tomography for detection of small liver lesions: comparison using a virtual framework imaging.

Journal Article J Med Imaging (Bellingham) · September 2024 PURPOSE: Photon-counting computed tomography (PCCT) has the potential to provide superior image quality to energy-integrating CT (EICT). We objectively compare PCCT to EICT for liver lesion detection. APPROACH: Fifty anthropomorphic, computational phantoms ... Full text Link to item Cite

Protocol optimization for abdominal imaging using photon-counting CT: a consensus of two academic institutions.

Journal Article Abdom Radiol (NY) · May 2024 PURPOSE: Photon-counting detector CT (PCD CT) is a promising technology for abdominal imaging due to its ability to provide high spatial and contrast resolution images with reduced patient radiation exposure. However, there is currently no consensus regard ... Full text Link to item Cite

First experience of evaluation of the impact of high-matrix size reconstruction in image quality in arterial CT runoff studies of the lower extremities.

Journal Article Eur Radiol · December 2023 OBJECTIVES: To determine whether image reconstruction with a higher matrix size improves image quality for lower extremity CTA studies. METHODS: Raw data from 50 consecutive lower extremity CTA studies acquired on two MDCT scanners (SOMATOM Flash, Force) i ... Full text Link to item Cite

Photon Counting Computed Tomography-Applications.

Journal Article Radiol Clin North Am · November 2023 Photon-counting detector CT (PCCT) is a new technology that has recently emerged as a powerful tool for a more precise, patient-centered imaging. Ever since the FDA approved the first Photon-counting system on September 30, 2021, this new technology raised ... Full text Link to item Cite

Dual-Energy Computed Tomography to Photon Counting Computed Tomography: Emerging Technological Innovations.

Journal Article Radiol Clin North Am · November 2023 Computed tomography (CT) has seen remarkable developments in the past several decades, radically transforming the role of imaging in day-to-day clinical practice. Dual-energy CT (DECT), an exciting innovation introduced in the early part of this century, h ... Full text Link to item Cite

Unveiling the Spectrum: Dual-Energy Computed Tomography and Beyond!

Journal Article Radiol Clin North Am · November 2023 Full text Link to item Cite

Evaluation of the impact of a novel denoising algorithm on image quality in dual-energy abdominal CT of obese patients.

Journal Article Eur Radiol · October 2023 OBJECTIVES: Evaluate a novel algorithm for noise reduction in obese patients using dual-source dual-energy (DE) CT imaging. METHODS: Seventy-nine patients with contrast-enhanced abdominal imaging (54 women; age: 58 ± 14 years; BMI: 39 ± 5 kg/m2, range: 35- ... Full text Open Access Link to item Cite

Optimization of non-endorectal prostate MR image quality using PI-QUAL: A multidisciplinary team approach.

Journal Article Eur J Radiol · September 2023 PURPOSE: To evaluate the utility of the PI-QUAL score in assessing protocol changes aimed to improve image quality from a non-endorectal coil prostate MR imaging protocol during a 9-month quality improvement (QI) project and to quantify the inter-reader ag ... Full text Link to item Cite

Image quality of photon counting and energy integrating chest CT - Prospective head-to-head comparison on same patients.

Journal Article Eur J Radiol · September 2023 PURPOSE: To prospectively compare the image quality of high-resolution, low-dose photon-counting detector CT (PCD-CT) with standard energy-integrating-detector CT (EID) on the same patients. METHOD: IRB-approved, prospective study; patients received same-d ... Full text Open Access Link to item Cite

Exploratory analysis of mesenteric-portal axis CT radiomic features for survival prediction of patients with pancreatic ductal adenocarcinoma.

Journal Article Eur Radiol · August 2023 OBJECTIVE: To develop and evaluate task-based radiomic features extracted from the mesenteric-portal axis for prediction of survival and response to neoadjuvant therapy in patients with pancreatic ductal adenocarcinoma (PDAC). METHODS: Consecutive patients ... Full text Link to item Cite

Exploiting the Potential of Photon-Counting CT in Abdominal Imaging.

Journal Article Invest Radiol · July 1, 2023 Photon-counting computed tomography (PCCT) imaging uses a new detector technology to provide added information beyond what can already be obtained with current CT and MR technologies. This review provides an overview of PCCT of the abdomen and focuses spec ... Full text Link to item Cite

Liver fat quantification in photon counting CT in head to head comparison with clinical MRI - First experience.

Journal Article Eur J Radiol · April 2023 PURPOSE: To compare liver fat quantification between MRI and photon-counting CT (PCCT). METHOD: A cylindrical phantom with inserts containing six concentrations of oil (0, 10, 20, 30, 50 and 100%) and oil-iodine mixtures (0, 10, 20, 30 and 50% fat +3 mg/mL ... Full text Link to item Cite

Is it possible to use low-dose deep learning reconstruction for the detection of liver metastases on CT routinely?

Journal Article Eur Radiol · March 2023 OBJECTIVES: To compare the image quality and hepatic metastasis detection of low-dose deep learning image reconstruction (DLIR) with full-dose filtered back projection (FBP)/iterative reconstruction (IR). METHODS: A contrast-detail phantom consisting of lo ... Full text Link to item Cite

Coronary Artery Calcium Evaluation Using New Generation Photon-counting Computed Tomography Yields Lower Radiation Dose Compared With Standard Computed Tomography.

Journal Article J Thorac Imaging · January 1, 2023 Prospective head-to-head comparison of coronary calcium scores between standard computed tomography (CT) and photon-counting CT show no significant differences, while photon-counting CT administers substantially lower radiation dose. ... Full text Link to item Cite

Deep learning image reconstruction for optimizing image quality of low-energy spectral monochromatic CT and detecting liver small low-contrast lesions

Journal Article Chinese Journal of Medical Imaging Technology · January 1, 2023 Objective To investigate the feasibility of deep learning image reconstruction (DLIR) for optimizing image quality of low-energy spectral monochromatic CT and improving detection of liver small low-contrast lesions. Methods Thirty patients with 58 hepatic ... Full text Cite

Unsupervised learning of robust models for cardiac and photon-counting x-ray CT denoising

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2023 Supervised deep learning methods have rapidly advanced to the forefront of medical imaging research; however, they face limitations in advanced CT applications. For instance, label generation is difficult for retrospective cardiac CT data where dose modula ... Full text Cite

A patient-informed approach to predict iodinated-contrast media enhancement in the liver.

Journal Article Eur J Radiol · November 2022 OBJECTIVE: To devise a patient-informed time series model that predicts liver contrast enhancement, by integrating clinical data and pharmacokinetics models, and to assess its feasibility to improve enhancement consistency in contrast-enhanced liver CT sca ... Full text Open Access Link to item Cite

ACR Appropriateness Criteria® Right Lower Quadrant Pain: 2022 Update.

Journal Article J Am Coll Radiol · November 2022 This document focuses on imaging in the adult and pregnant populations with right lower quadrant (RLQ) abdominal pain, including patients with fever and leukocytosis. Appendicitis remains the most common surgical pathology responsible for RLQ abdominal pai ... Full text Link to item Cite

ACR Appropriateness Criteria® Hernia.

Journal Article J Am Coll Radiol · November 2022 Abdominopelvic hernias are common clinical entities composed of a wide variety of congenital, traumatic, and iatrogenic etiologies. Any weakness in the body wall may result in hernia of cavity contents with concomitant risks of morbidity and mortality. Pre ... Full text Link to item Cite

Can radiomic analysis of a single-phase dual-energy CT improve the diagnostic accuracy of differentiating enhancing from non-enhancing small renal lesions?

Journal Article Acta Radiol · June 2022 BACKGROUND: The value of dual-energy computed tomography (DECT)-based radiomics in renal lesions is unknown. PURPOSE: To develop DECT-based radiomic models and assess their incremental values in comparison to conventional measurements for differentiating e ... Full text Link to item Cite

Dual energy CT for the identification of CSF-Venous Fistulas and CSF leaks in spontaneous intracranial hypotension: Report of four cases.

Journal Article Radiol Case Rep · May 2022 Spontaneous intracranial hypotension (SIH) is a debilitating condition caused by spinal CSF leaks or CSF-venous fistulas (CVFs). Localizing the causative CSF leak or CVF is critical for definitive treatment but can be difficult using conventional myelograp ... Full text Link to item Cite

ACR Appropriateness Criteria® Staging of Colorectal Cancer: 2021 Update.

Journal Article J Am Coll Radiol · May 2022 Preoperative imaging of rectal carcinoma involves accurate assessment of the primary tumor as well as distant metastatic disease. Preoperative imaging of nonrectal colon cancer is most beneficial in identifying distant metastases, regardless of primary T o ... Full text Link to item Cite

Dual-Energy CT Vital Iodine Tumor Burden for Response Assessment in Patients With Metastatic GIST Undergoing TKI Therapy: Comparison With Standard CT and FDG PET/CT Criteria.

Journal Article AJR Am J Roentgenol · April 2022 BACKGROUND. CT-based criteria for assessing the gastrointestinal stromal tumor (GIST) response to tyrosine kinase inhibitor (TKI) therapy are limited in part because tumor attenuation is influenced by treatment-related changes including hemorrhage and calc ... Full text Link to item Cite

Left lateral segment liver volume is not correlated with anthropometric measures.

Journal Article HPB (Oxford) · December 2021 BACKGROUND: Liver transplantation is definitive therapy for end stage liver disease in pediatric patients. Living donor liver transplantation (LDLT) with the left lateral segment (LLS) is often a feasible option. However, the size of LLS is an important fa ... Full text Link to item Cite

Diagnostic performance of single-phase dual-energy CT to differentiate vascular and nonvascular incidental renal lesions on portal venous phase: comparison with CT.

Journal Article European radiology · December 2021 ObjectivesTo determine whether single-phase dual-energy CT (DECT) differentiates vascular and nonvascular renal lesions in the portal venous phase (PVP). Optimal iodine threshold was determined and compared to Hounsfield unit (HU) measurements. Full text Cite

CT Radiomic Features of Superior Mesenteric Artery Involvement in Pancreatic Ductal Adenocarcinoma: A Pilot Study.

Journal Article Radiology · December 2021 Background Current imaging methods for prediction of complete margin resection (R0) in patients with pancreatic ductal adenocarcinoma (PDAC) are not reliable. Purpose To investigate whether tumor-related and perivascular CT radiomic features improve preope ... Full text Open Access Link to item Cite

ACR Appropriateness Criteria® Anorectal Disease.

Journal Article J Am Coll Radiol · November 2021 This review summarizes the relevant literature for the selection of the initial imaging in 4 clinical scenarios in patients with suspected inflammatory disease or postoperative complication of the anorectum. These clinical scenarios include suspected peria ... Full text Link to item Cite

Clinical Implementation of Dual-Energy CT for Gastrointestinal Imaging.

Journal Article AJR Am J Roentgenol · September 2021 Dual-energy CT (DECT) overcomes several limitations of conventional single-energy CT (SECT) for the evaluation of gastrointestinal diseases. This article provides an overview of practical aspects of the DECT technology and acquisition protocols, reviews ex ... Full text Link to item Cite

Can procedure time for paracentesis be optimized based on bottle selection?

Journal Article Abdom Radiol (NY) · August 2021 PURPOSE: The purpose of our study was to assess if plastic containers could decrease the overall procedure time for paracentesis relative to more commonly used glass containers. METHODS: In this IRB exempt study, initial pilot data comparing filling time o ... Full text Link to item Cite

Multisite multivendor validation of a quantitative MRI and CT compatible fat phantom.

Journal Article Med Phys · August 2021 PURPOSE: Chemical shift-encoded magnetic resonance imaging enables accurate quantification of liver fat content though estimation of proton density fat-fraction (PDFF). Computed tomography (CT) is capable of quantifying fat, based on decreased attenuation ... Full text Link to item Cite

Effect of deep learning image reconstruction in the prediction of resectability of pancreatic cancer: Diagnostic performance and reader confidence.

Journal Article Eur J Radiol · August 2021 OBJECTIVE: To assess the diagnostic performance and reader confidence in determining the resectability of pancreatic cancer at computed tomography (CT) using a new deep learning image reconstruction (DLIR) algorithm. METHODS: A retrospective review was con ... Full text Link to item Cite

Evaluating renal lesions using deep-learning based extension of dual-energy FoV in dual-source CT-A retrospective pilot study.

Journal Article Eur J Radiol · June 2021 PURPOSE: Dual-source (DS) CT, dual-energy (DE) field of view (FoV) is limited to the size of the smaller detector array. The purpose was to establish a deep learning-based approach to DE extrapolation by estimating missing image data using data from both t ... Full text Open Access Link to item Cite

Automated coronary calcium scoring using deep learning with multicenter external validation.

Journal Article NPJ digital medicine · June 2021 Coronary artery disease (CAD), the most common manifestation of cardiovascular disease, remains the most common cause of mortality in the United States. Risk assessment is key for primary prevention of coronary events and coronary artery calcium (CAC) scor ... Full text Cite

ACR Appropriateness Criteria® Radiologic Management of Lower Gastrointestinal Tract Bleeding: 2021 Update.

Journal Article J Am Coll Radiol · May 2021 Diverticulosis remains the commonest cause for acute lower gastrointestinal tract bleeding (GIB). Conservative management is initially sufficient for most patients, followed by elective diagnostic tests. However, if acute lower GIB persists, it can be inve ... Full text Link to item Cite

How frequently does hepatocellular carcinoma develop in at-risk patients with a negative liver MRI examination with intravenous Gadobenate dimeglumine?

Journal Article Abdom Radiol (NY) · March 2021 OBJECTIVE: To determine the rate of development of clinically significant liver nodules (LR-4, LR-5, LR-M) after a negative MRI in an HCC screening population. METHODS: This retrospective study included patients at risk of developing HCC requiring imaging ... Full text Link to item Cite

LRP1B mutations are associated with favorable outcomes to immune checkpoint inhibitors across multiple cancer types.

Journal Article J Immunother Cancer · March 2021 BACKGROUND: Low-density lipoprotein receptor-related protein 1b (encoded by LRP1B) is a putative tumor suppressor, and preliminary evidence suggests LRP1B-mutated cancers may have improved outcomes with immune checkpoint inhibitors (ICI). METHODS: We condu ... Full text Open Access Link to item Cite

"Bull's eye" appearance of hepatocellular adenomas in patients with glycogen storage disease type I - atypical magnetic resonance imaging findings: Two case reports.

Journal Article World J Clin Cases · February 6, 2021 BACKGROUND: Hepatocellular adenomas are rare tumors that can occur in patients with glycogen storage disease type I. CASE SUMMARY: We herein report two cases of histologically proven hepatocellular adenomas in patients with glycogen storage disease type I. ... Full text Link to item Cite

CT and MR imaging evaluation of living liver donors.

Journal Article Abdom Radiol (NY) · January 2021 Preoperative cross-sectional imaging evaluation of potential living liver donors allows to exclude donors with an increased risk for morbidity and mortality, and to assure that a suitable graft for the recipient can be obtained, minimizing the risk of comp ... Full text Link to item Cite

Variability of quantitative measurements of metastatic liver lesions: a multi-radiation-dose-level and multi-reader comparison.

Journal Article Abdom Radiol (NY) · January 2021 PURPOSE: To evaluate the variability of quantitative measurements of metastatic liver lesions by using a multi-radiation-dose-level and multi-reader comparison. METHODS: Twenty-three study subjects (mean age, 60 years) with 39 liver lesions who underwent a ... Full text Link to item Cite

Automated patient-specific and organ-based image quality metrics on dual-energy ct datasets for large scale studies

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2021 The purpose of this study was to develop an automated patient-specific and organ-based image quality (IQ) assessment tool for dual energy (DE) computed tomography (CT) images for large scale clinical analysis. To demonstrate its utility, this tool was used ... Full text Cite

Seeing is believing: A roadmap for implementing bolus-tracked multiphasic CT simulation for ablative radiotherapy of abdominal malignancies.

Journal Article J Radiosurg SBRT · 2021 Link to item Cite

Split-Bolus, Single-Acquisition, Dual-Phase Abdominopelvic CT Angiography for the Evaluation of Lung Transplant Candidates: Image Quality and Resource Utilization.

Journal Article AJR Am J Roentgenol · December 2020 OBJECTIVE. The purpose of this study was to assess the image quality and resource utilization of single-injection, split-bolus, dual-enhancement abdominopelvic CT angiography (hereafter referred to as dual-enhancement CTA) performed for combined vascular a ... Full text Link to item Cite

Noise and spatial resolution properties of a commercially available deep learning-based CT reconstruction algorithm.

Journal Article Med Phys · September 2020 PURPOSE: To characterize the noise and spatial resolution properties of a commercially available deep learning-based computed tomography (CT) reconstruction algorithm. METHODS: Two phantom experiments were performed. The first used a multisized image quali ... Full text Link to item Cite

Deep learning based spectral extrapolation for dual-source, dual-energy x-ray computed tomography.

Journal Article Med Phys · September 2020 PURPOSE: Data completion is commonly employed in dual-source, dual-energy computed tomography (CT) when physical or hardware constraints limit the field of view (FoV) covered by one of two imaging chains. Practically, dual-energy data completion is accompl ... Full text Open Access Link to item Cite

Impact of dual energy cardiac CT for metal artefact reduction post aortic valve replacement.

Journal Article Eur J Radiol · August 2020 PURPOSE: Assess image quality of dual-energy (DE) and single-energy (SE) cardiac multi-detector computed tomographic (MDCT) post aortic valve replacement (AVR) on a dual source MDCT scanner. METHODS: Eighty patients with cardiac MDCT acquisitions (ECG gate ... Full text Link to item Cite

Liver Imaging Reporting and Data System (LI-RADS) v2018: diagnostic value of ancillary features favoring malignancy in hypervascular observations ≥ 10 mm at intermediate (LR-3) and high probability (LR-4) for hepatocellular carcinoma.

Journal Article Eur Radiol · July 2020 OBJECTIVE: This study was conducted in order to assess the diagnostic accuracy of LI-RADS v2018 ancillary features (AFs) favoring malignancy applied to LR-3 and LR-4 observations on gadoxetate-enhanced MRI. METHODS: In this retrospective dual-institution s ... Full text Link to item Cite

Hepatobiliary phase hypointensity predicts progression to hepatocellular carcinoma for intermediate-high risk observations, but not time to progression.

Journal Article Eur J Radiol · July 2020 PURPOSE: To determine whether hepatobiliary phase hypointensity, enhancing "capsule" and size provide prognostic information regarding the risk of progression to hepatocellular carcinoma (HCC), as well as the time to progression, of intermediate to high ri ... Full text Link to item Cite

Cost-effectiveness of dual-energy CT versus multiphasic single-energy CT and MRI for characterization of incidental indeterminate renal lesions.

Journal Article Abdom Radiol (NY) · June 2020 PURPOSE: To evaluate the cost-effectiveness of DECT versus multiphasic CT and MRI for characterizing small incidentally detected indeterminate renal lesions using a Markov Monte Carlo decision-analytic model. BACKGROUND: Incidental renal lesions are common ... Full text Link to item Cite

Ultrasound-guided non-targeted liver core biopsy: comparison of the efficacy of two different core needle biopsy systems using an ex-vivo animal model and retrospective review of clinical experience.

Journal Article Clin Imaging · May 2020 PURPOSE: To compare the efficacy of two 18-gauge core needle biopsy systems, the Achieve® (Merit Medical) and the Marquee® (BD Bard), using an ex-vivo animal liver model and retrospective review of clinical experience. METHODS: Sixty ex-vivo liver biopsy s ... Full text Link to item Cite

ACR Appropriateness Criteria® Suspected Small-Bowel Obstruction.

Journal Article J Am Coll Radiol · May 2020 Small-bowel obstruction is a common cause of abdominal pain and accounts for a significant proportion of hospital admissions. Radiologic imaging plays the key role in the diagnosis and management of small-bowel obstruction as neither patient presentation, ... Full text Link to item Cite

ACR Appropriateness Criteria® Crohn Disease.

Journal Article Journal of the American College of Radiology : JACR · May 2020 Three common clinical scenarios involving use of imaging in Crohn disease are covered. These include the initial evaluation of Crohn disease when the diagnosis has not been previously established, the evaluation for anticipated exacerbation of known diseas ... Full text Cite

Correlation of preoperative imaging characteristics with donor outcomes and operative difficulty in laparoscopic donor nephrectomy.

Journal Article Am J Transplant · March 2020 This study aimed to understand the relationship of preoperative measurements and risk factors on operative time and outcomes of laparoscopic donor nephrectomy. Two hundred forty-two kidney donors between 2010 and 2017 were identified. Patients' demographic ... Full text Open Access Link to item Cite

VISUAL VIGNETTE.

Chapter · March 2020 Full text Link to item Cite

Evaluation of Intraindividual Contrast Enhancement Variability for Determining the Maximum Achievable Consistency in CT.

Journal Article AJR Am J Roentgenol · January 2020 OBJECTIVE. The purpose of this study was to quantify temporal variability in vascular and parenchymal enhancement within the same patient and to determine technique-related factors contributing to this variability. MATERIALS AND METHODS. We identified 100 ... Full text Link to item Cite

Reproducibility of CT Radiomic Features within the Same Patient: Influence of Radiation Dose and CT Reconstruction Settings.

Journal Article Radiology · December 2019 Background Results of recent phantom studies show that variation in CT acquisition parameters and reconstruction techniques may make radiomic features largely nonreproduceable and of limited use for prognostic clinical studies. Purpose To investigate the e ... Full text Link to item Cite

Local Tumor Control and Patient Outcome Using Stereotactic Body Radiation Therapy for Hepatocellular Carcinoma: iRECIST as a Potential Substitute for Traditional Criteria.

Journal Article AJR Am J Roentgenol · December 2019 OBJECTIVE. The purpose of this study was to investigate whether, compared with traditional criteria, the modified Response Evaluation Criteria in Solid Tumors version 1.1 for immune-based therapeutics (iRECIST) improves prediction of local tumor control an ... Full text Link to item Cite

Clinical utility of FoundationOne tissue molecular profiling in men with metastatic prostate cancer.

Journal Article Urol Oncol · November 2019 PURPOSE: Targeted inhibitors and immunotherapy have entered the treatment landscape of metastatic prostate cancer. Genomic testing may uncover which patients benefit most from these therapies. We report the clinical utility and benefits of FoundationOne te ... Full text Link to item Cite

Validation of algorithmic CT image quality metrics with preferences of radiologists.

Journal Article Med Phys · November 2019 PURPOSE: Automated assessment of perceptual image quality on clinical Computed Tomography (CT) data by computer algorithms has the potential to greatly facilitate data-driven monitoring and optimization of CT image acquisition protocols. The application of ... Full text Open Access Link to item Cite

ACR Appropriateness Criteria® Palpable Abdominal Mass-Suspected Neoplasm.

Journal Article J Am Coll Radiol · November 2019 Palpable abdominal masses may arise from the abdominal cavity or the abdominal wall. The differential diagnosis is broad for each variant ranging from benign lipomas, inflammatory processes, to malignant tumors. The imaging approach to diagnosis varies by ... Full text Link to item Cite

A Simulation Paradigm for Evaluation of Subtle Liver Lesions at Pediatric CT: Performance and Confidence.

Journal Article Radiol Imaging Cancer · September 2019 PURPOSE: To create and validate a systematic observer performance platform for evaluation of simulated liver lesions at pediatric CT and to test this paradigm to measure the effect of radiation dose reduction on detection performance and reader confidence. ... Full text Link to item Cite

LI-RADS: Diagnostic Performance of Hepatobiliary Phase Hypointensity and Major Imaging Features of LR-3 and LR-4 Lesions Measuring 10-19 mm With Arterial Phase Hyperenhancement.

Journal Article AJR Am J Roentgenol · August 2019 OBJECTIVE. The purpose of this study was to determine the diagnostic performance of hepatobiliary phase hypointensity and Liver Imaging Reporting and Data System (LI-RADS) major imaging features in the diagnosis of hepatocellular carcinoma (HCC) in hepatic ... Full text Link to item Cite

Pembrolizumab in men with heavily treated metastatic castrate-resistant prostate cancer.

Journal Article Cancer Med · August 2019 BACKGROUND: Pembrolizumab is approved for patients with metastatic, microsatellite instability (MSI)-high or mismatch repair-deficient (dMMR) solid tumors. However, very few men with prostate cancer were included in these initial studies. METHODS: We perfo ... Full text Link to item Cite

Comparison of Iodine Quantification and Conventional Attenuation Measurements for Differentiating Small, Truly Enhancing Renal Masses From High-Attenuation Nonenhancing Renal Lesions With Dual-Energy CT.

Journal Article AJR Am J Roentgenol · July 2019 OBJECTIVE. The purpose of this study is to determine whether iodine quantification techniques from contrast-enhanced dual-energy CT (DECT) data allow equal differentiation of small enhancing renal masses from high-attenuation (> 20 HU of unenhanced attenua ... Full text Link to item Cite

Systematic analysis of bias and variability of texture measurements in computed tomography.

Journal Article J Med Imaging (Bellingham) · July 2019 Texture is a key radiomics measurement for quantification of disease and disease progression. The sensitivity of the measurements to image acquisition, however, is uncertain. We assessed bias and variability of computed tomography (CT) texture feature meas ... Full text Link to item Cite

Can virtual monochromatic images from dual-energy CT replace low-kVp images for abdominal contrast-enhanced CT in small- and medium-sized patients?

Journal Article Eur Radiol · June 2019 OBJECTIVE: To investigate the image quality and radiation dose of dual-energy computed tomography (DECT) with automatic spectral imaging protocol selection (ASIS) compared with those of low-kVp CT in abdominal multiphase CT. METHODS: Four groups of 60 pati ... Full text Link to item Cite

Systematic Review and Meta-Analysis Investigating the Diagnostic Yield of Dual-Energy CT for Renal Mass Assessment.

Journal Article AJR Am J Roentgenol · May 2019 OBJECTIVE. The objective of our study was to perform a systematic review and meta-analysis to evaluate the diagnostic accuracy of dual-energy CT (DECT) for renal mass evaluation. MATERIALS AND METHODS. In March 2018, we searched MEDLINE, Cochrane Database ... Full text Link to item Cite

Virtual Unenhanced Images at Dual-Energy CT: Influence on Renal Lesion Characterization.

Journal Article Radiology · May 2019 Background Dual-energy (DE) CT allows reconstruction of virtual noncontrast (VNC) images from a single-phase contrast agent-enhanced examination, potentially reducing the need for multiphasic CT to characterize renal lesions. However, data regarding diagno ... Full text Link to item Cite

ACR Appropriateness Criteria® Dysphagia.

Journal Article J Am Coll Radiol · May 2019 This review summarizes the relevant literature for the initial imaging of patients with symptoms of dysphagia. For patients with oropharyngeal dysphagia who have an underlying attributable cause, a modified barium swallow is usually appropriate for initial ... Full text Link to item Cite

ACR Appropriateness Criteria® Left Lower Quadrant Pain-Suspected Diverticulitis.

Journal Article J Am Coll Radiol · May 2019 This review summarizes the relevant literature regarding imaging of suspected diverticulitis as an etiology for left lower quadrant pain, and imaging of complications of acute diverticulitis. The most common cause of left lower quadrant pain in adults is a ... Full text Link to item Cite

Design and fabrication of heterogeneous lung nodule phantoms for assessing the accuracy and variability of measured texture radiomics features in CT.

Journal Article J Med Imaging (Bellingham) · April 2019 We aimed to design and fabricate synthetic lung nodules with patient-informed internal heterogeneity to assess the variability and accuracy of measured texture features in CT. To that end, 190 lung nodules from a publicly available database of chest CT ima ... Full text Link to item Cite

Can Texture Analysis Be Used to Distinguish Benign From Malignant Adrenal Nodules on Unenhanced CT, Contrast-Enhanced CT, or In-Phase and Opposed-Phase MRI?

Journal Article AJR Am J Roentgenol · March 2019 OBJECTIVE: The purpose of this study is to determine whether second-order texture analysis can be used to distinguish lipid-poor adenomas from malignant adrenal nodules on unenhanced CT, contrast-enhanced CT (CECT), and chemical-shift MRI. MATERIALS AND ME ... Full text Link to item Cite

High-Pitch Wide-Coverage Fast-Kilovoltage-Switching Dual-Energy CT: Impact of Pitch on Noise, Spatial Resolution, and Iodine Quantification in a Phantom Study.

Journal Article AJR Am J Roentgenol · March 2019 OBJECTIVE: The purpose of this study was to assess the impact of high pitch values on image noise, spatial resolution, and iodine quantification in single-source wide-coverage fast-kilovoltage-switching dual-energy CT (DECT). MATERIALS AND METHODS: Two pha ... Full text Link to item Cite

Negative Biopsy of Focal Hepatic Lesions: Decision Tree Model for Patient Management.

Journal Article AJR Am J Roentgenol · March 2019 OBJECTIVE: The purpose of this study was to investigate patient- and procedure-related variables affecting the false-negative rate of ultrasound (US)-guided liver biopsy and to develop a standardized patient-tailored predictive model for the management of ... Full text Link to item Cite

Dual-Energy CT Material Density Iodine Quantification for Distinguishing Vascular From Nonvascular Renal Lesions: Normalization Reduces Intermanufacturer Threshold Variability.

Journal Article AJR Am J Roentgenol · February 2019 OBJECTIVE: The purpose of this study was to determine whether a single, uniform normalized iodine threshold reduces variability and enables reliable differentiation between vascular and nonvascular renal lesions independent of the dual-energy CT (DECT) pla ... Full text Link to item Cite

Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients.

Journal Article J Immunother Cancer · February 1, 2019 BACKGROUND: Resistance to immune checkpoint inhibitors (ICIs) has been linked to local immunosuppression independent of major ICI targets (e.g., PD-1). Clinical experience with response prediction based on PD-L1 expression suggests that other factors influ ... Full text Link to item Cite

Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors.

Journal Article J Immunother Cancer · January 24, 2019 BACKGROUND: PD-L1 immunohistochemistry (IHC) has been traditionally used for predicting clinical responses to immune checkpoint inhibitors (ICIs). However, there are at least 4 different assays and antibodies used for PD-L1 IHC, each developed with a diffe ... Full text Link to item Cite

Kidneys, ureters, and bladder

Chapter · January 1, 2019 The kidneys are situated in the perirenal space, which is enclosed by the anterior (Gerota) and posterior renal fasciae and located on the posterior abdominal wall on each side of the vertebral column. The kidney’s three-dimensional orientation is parallel ... Full text Cite

CT material identification

Chapter · January 1, 2019 Technical advances in CT imaging have improved ability to discriminate different materials, going beyond the attenuation imaging provided by most current systems. Nowadays, dual-energy CT systems allow for material identification and quantification providi ... Full text Cite

Intratreatment Response Assessment With 18F-FDG PET: Correlation of Semiquantitative PET Features With Pathologic Response of Esophageal Cancer to Neoadjuvant Chemoradiotherapy.

Journal Article Int J Radiat Oncol Biol Phys · November 15, 2018 PURPOSE: This prospective study seeks to extract semiquantitative positron emission tomography (PET) features from 18F-fluorodeoxyglucose PET scans performed before and during neoadjuvant chemoradiotherapy for esophageal cancer and to compare their accurac ... Full text Link to item Cite

ACR Appropriateness Criteria® Right Lower Quadrant Pain-Suspected Appendicitis.

Journal Article J Am Coll Radiol · November 2018 Appendicitis remains the most common surgical pathology responsible for right lower quadrant (RLQ) abdominal pain presenting to emergency departments in the United States, where the incidence continues to increase. Appropriate imaging in the diagnosis of a ... Full text Link to item Cite

ACR Appropriateness Criteria® Acute Nonlocalized Abdominal Pain.

Journal Article J Am Coll Radiol · November 2018 The range of pathology in adults that can produce abdominal pain is broad and necessitates an imaging approach to evaluate many different organ systems. Although localizing pain prompts directed imaging/management, clinical presentations may vary and resul ... Full text Link to item Cite

CT evaluation of the renal donor and recipient.

Journal Article Abdom Radiol (NY) · October 2018 Proper pre- and post-transplant diagnostic imaging work-up is fundamental in ensuring a successful outcome for renal transplantation. Despite exposure to ionizing radiation, CT has high spatial resolution and is a widely available and fast imaging techniqu ... Full text Link to item Cite

The role of MR imaging in the assessment of renal allograft vasculature.

Journal Article Abdom Radiol (NY) · October 2018 Renal allograft dysfunction after transplantation is a relatively common occurrence with various potential etiologies. Vascular etiologies are of particular importance as early surgical or minimally invasive intervention can, in some cases, salvage the gra ... Full text Link to item Cite

Abdominal Radiography With Digital Tomosynthesis: An Alternative to Computed Tomography for Identification of Urinary Calculi?

Journal Article Urology · October 2018 OBJECTIVE: To compare the accuracy of plain abdominal radiography (kidneys, ureter, and bladder [KUB]) with digital tomosynthesis (DT) to noncontrast computed tomography (NCCT), the gold standard imaging modality for urinary stones. Due to radiation and co ... Full text Link to item Cite

The role of external beam radiotherapy in the treatment of hepatocellular cancer.

Journal Article Cancer · September 1, 2018 Hepatocellular carcinoma (HCC) is increasing in incidence and mortality. Although the prognosis remains poor, long-term survival has improved from 3% in 1970 to an 18% 5-year survival rate today. This is likely because of the introduction of well tolerated ... Full text Link to item Cite

Characterization of Small Incidental Indeterminate Hypoattenuating Hepatic Lesions: Added Value of Single-Phase Contrast-Enhanced Dual-Energy CT Material Attenuation Analysis.

Journal Article AJR Am J Roentgenol · September 2018 OBJECTIVE: The objective of this study is to determine whether single-phase contrast-enhanced dual-energy CT (DECT) material attenuation analysis improves the characterization of small (< 2.0 cm) incidental indeterminate hypoattenuating hepatic lesions, co ... Full text Link to item Cite

Comparison of image quality and radiation dose between split-filter dual-energy images and single-energy images in single-source abdominal CT.

Journal Article Eur Radiol · August 2018 OBJECTIVES: To compare image quality and radiation dose of abdominal split-filter dual-energy CT (SF-DECT) combined with monoenergetic imaging to single-energy CT (SECT) with automatic tube voltage selection (ATVS). METHODS: Two-hundred single-source abdom ... Full text Link to item Cite

Use of Dual-Energy Computed Tomography for Evaluation of Genitourinary Diseases.

Journal Article Urol Clin North Am · August 2018 Since its clinical inception a decade ago, dual-energy computed tomography has expanded the array of computed tomography imaging tools available to the practicing abdominal radiologist. Of note, diagnostic solutions for imaging-based evaluation of genitour ... Full text Link to item Cite

Strategies to Improve Image Quality on Dual-Energy Computed Tomography.

Journal Article Radiol Clin North Am · July 2018 Dual-energy computed tomography (DECT) offers several advantages over conventional single-energy CT. These advantages include improved image quality, beam hardening correction, and metal artifact reduction. Additionally, DECT allows derivation of quantitat ... Full text Link to item Cite

Renal Lesion Characterization with Spectral CT: Determining the Optimal Energy for Virtual Monoenergetic Reconstruction.

Journal Article Radiology · June 2018 Purpose To investigate the relationship between energy level of virtual monoenergetic (VM) imaging and sensitivity in the detection of minimally enhancing renal lesions. Materials and Methods Phantoms simulating unenhanced and contrast material-enhanced re ... Full text Link to item Cite

A Third-Generation Adaptive Statistical Iterative Reconstruction Technique: Phantom Study of Image Noise, Spatial Resolution, Lesion Detectability, and Dose Reduction Potential.

Journal Article AJR Am J Roentgenol · June 2018 OBJECTIVE: The purpose of this study was to assess image noise, spatial resolution, lesion detectability, and the dose reduction potential of a proprietary third-generation adaptive statistical iterative reconstruction (ASIR-V) technique. MATERIALS AND MET ... Full text Link to item Cite

Tin-filtered low-dose chest CT to quantify macroscopic calcification burden of the thoracic aorta.

Journal Article Eur Radiol · May 2018 OBJECTIVES: To compare a low-dose, tin-filtered, nonenhanced, high-pitch Sn100 kVp CT protocol (Sn100) with a standard protocol (STP) for the detection of calcifications in the ascending aorta in patients scheduled for cardiac surgery. METHODS: Institution ... Full text Link to item Cite

Progression of Treated versus Untreated Liver Imaging Reporting and Data System Category 4 Masses after Transcatheter Arterial Embolization Therapy.

Journal Article J Vasc Interv Radiol · May 2018 PURPOSE: To compare outcomes of treated vs untreated Liver Imaging Reporting and Data System category 4 (LR-4) masses after transcatheter arterial embolization. MATERIALS AND METHODS: In 167 patients undergoing embolization for HCC from January 2005 to Dec ... Full text Link to item Cite

Energy-Specific Optimization of Attenuation Thresholds for Low-Energy Virtual Monoenergetic Images in Renal Lesion Evaluation.

Journal Article AJR Am J Roentgenol · May 2018 OBJECTIVE: The purpose of this study was to determine in vitro and in vivo the optimal threshold for renal lesion vascularity at low-energy (40-60 keV) virtual monoenergetic imaging. MATERIALS AND METHODS: A rod simulating unenhanced renal parenchymal atte ... Full text Link to item Cite

ACR Appropriateness Criteria® Colorectal Cancer Screening.

Journal Article J Am Coll Radiol · May 2018 This review summarizes the relevant literature regarding colorectal screening with imaging. For individuals at average or moderate risk for colorectal cancer, CT colonography is usually appropriate for colorectal cancer screening. After positive results on ... Full text Link to item Cite

Clinically Acceptable Optimized Dose Reduction in Computed Tomographic Imaging of Necrotizing Pancreatitis Using a Noise Addition Software Tool.

Journal Article J Comput Assist Tomogr · 2018 OBJECTIVE: This study aimed to determine potential radiation dose reduction of contrast-enhanced computed tomography (CECT) for imaging necrotizing pancreatitis (NP) using a noise addition tool. METHODS: Eighty-four patients were identified with at least 1 ... Full text Link to item Cite

How reliable are texture measurements?

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2018 The purpose of this study was to assess the bias (objectivity) and variability (robustness) of computed tomography (CT) texture features (internal heterogeneities) across a series of image acquisition settings and reconstruction algorithms. We simulated a ... Full text Cite

Optimizing window settings for improved presentation of virtual monoenergetic images in dual-energy computed tomography.

Journal Article Med Phys · November 2017 PURPOSE: Dual-energy computed tomography virtual monoenergetic imaging (VMI) at 40 keV exhibits superior contrast-to-noise ratio (CNR), although practicing radiologists do not consistently prefer it over VMI at 70 keV due to high perceivable noise. We hypo ... Full text Link to item Cite

Pilot Evaluation of Angiogenesis Signaling Factor Response after Transcatheter Arterial Embolization for Hepatocellular Carcinoma.

Journal Article Radiology · October 2017 Purpose To identify changes in a broad panel of circulating angiogenesis factors after bland transcatheter arterial embolization (TAE), a purely ischemic treatment for hepatocellular carcinoma (HCC). Materials and Methods This prospective HIPAA-compliant s ... Full text Link to item Cite

Characterization of Small (< 4 cm) Focal Renal Lesions: Diagnostic Accuracy of Spectral Analysis Using Single-Phase Contrast-Enhanced Dual-Energy CT.

Journal Article AJR Am J Roentgenol · October 2017 OBJECTIVE: The purpose of this study is to determine whether single-phase contrast-enhanced dual-energy quantitative spectral analysis improves the accuracy of diagnosis of small (< 4.0 cm) renal lesions, compared with conventional single-energy attenuatio ... Full text Link to item Cite

Effect of Radiation Dose Reduction and Reconstruction Algorithm on Image Noise, Contrast, Resolution, and Detectability of Subtle Hypoattenuating Liver Lesions at Multidetector CT: Filtered Back Projection versus a Commercial Model-based Iterative Reconstruction Algorithm.

Journal Article Radiology · September 2017 Purpose To determine the effect of radiation dose and iterative reconstruction (IR) on noise, contrast, resolution, and observer-based detectability of subtle hypoattenuating liver lesions and to estimate the dose reduction potential of the IR algorithm in ... Full text Link to item Cite

Characterization of Small Focal Renal Lesions: Diagnostic Accuracy with Single-Phase Contrast-enhanced Dual-Energy CT with Material Attenuation Analysis Compared with Conventional Attenuation Measurements.

Journal Article Radiology · September 2017 Purpose To determine whether single-phase contrast material-enhanced dual-energy material attenuation analysis improves the characterization of small (1-4 cm) renal lesions compared with conventional attenuation measurements by using histopathologic analys ... Full text Link to item Cite

Imaging Advances in Urolithiasis.

Journal Article J Endourol · July 2017 The prevalence of urinary stones in the United States has been described as 1 in 11 persons reporting a history of stones. Imaging plays a crucial role in diagnosis, management, and follow-up for these patients and imaging technology over the last 100 year ... Full text Link to item Cite

The Effect of Contrast Material on Radiation Dose at CT: Part I. Incorporation of Contrast Material Dynamics in Anthropomorphic Phantoms.

Journal Article Radiology · June 2017 Purpose To develop a method to incorporate the propagation of contrast material into computational anthropomorphic phantoms for estimation of organ dose at computed tomography (CT). Materials and Methods A patient-specific physiologically based pharmacokin ... Full text Link to item Cite

The Effect of Contrast Material on Radiation Dose at CT: Part II. A Systematic Evaluation across 58 Patient Models.

Journal Article Radiology · June 2017 Purpose To estimate the radiation dose as a result of contrast medium administration in a typical abdominal computed tomographic (CT) examination across a library of contrast material-enhanced computational patient models. Materials and Methods In part II ... Full text Link to item Cite

Variability in Radiation Dose From Repeat Identical CT Examinations: Longitudinal Analysis of 2851 Patients Undergoing 12,635 Thoracoabdominal CT Scans in an Academic Health System.

Journal Article AJR Am J Roentgenol · June 2017 OBJECTIVE: The purpose of this study was to conduct longitudinal analyses of radiation dose data from adult patients undergoing clinically indicated, repeat identical thoracoabdominal CT examinations. MATERIALS AND METHODS: Radiation dose data were electro ... Full text Link to item Cite

Dual-Source Single-Energy Multidetector CT Used to Obtain Multiple Radiation Exposure Levels within the Same Patient: Phantom Development and Clinical Validation.

Journal Article Radiology · May 2017 Purpose To develop, in a phantom environment, a method to obtain multidetector computed tomographic (CT) data sets at multiple radiation exposure levels within the same patient and to validate its use for potential dose reduction by using different image r ... Full text Link to item Cite

Use of Preprocedural MDCT for Cardiac Implantable Electric Device Lead Extraction: Frequency of Findings That Change Management.

Journal Article AJR Am J Roentgenol · April 2017 OBJECTIVE: Five percent of cardiac implantable electric devices (CIEDs) are removed each year. Percutaneous extraction is preferred but can be complicated if the leads adhere to the vasculature or perforate. The goal of this study is to assess the frequenc ... Full text Link to item Cite

Dual-energy CT workflow: multi-institutional consensus on standardization of abdominopelvic MDCT protocols.

Journal Article Abdom Radiol (NY) · March 2017 PURPOSE: To standardize workflow for dual-energy computed tomography (DECT) involving common abdominopelvic exam protocols. MATERIALS AND METHODS: 9 institutions (4 rsDECT, 1 dsDECT, 4 both) with 32 participants [average # years (range) in practice and DEC ... Full text Link to item Cite

Dual-Energy Computed Tomography in Genitourinary Imaging.

Journal Article Radiol Clin North Am · March 2017 Reignited by innovations in scanner engineering and software design, dual-energy computed tomography (CT) has come back into the clinical radiology arena in the last decade. Possibilities for noninvasive in vivo characterization of genitourinary disease, e ... Full text Link to item Cite

Use of a Noise Optimized Monoenergetic Algorithm for Patient-Size Independent Selection of an Optimal Energy Level During Dual-Energy CT of the Pancreas.

Journal Article J Comput Assist Tomogr · January 2017 PURPOSE: To investigate the impact of a second-generation noise-optimized monoenergetic algorithm on selection of the optimal energy level, image quality, and effect of patient body habitus for dual-energy multidetector computed tomography of the pancreas. ... Full text Link to item Cite

Accuracy and variability of texture-based radiomics features of lung lesions across CT imaging conditions

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2017 Texture analysis for lung lesions is sensitive to changing imaging conditions but these effects are not well understood, in part, due to a lack of ground-truth phantoms with realistic textures. The purpose of this study was to explore the accuracy and vari ... Full text Cite

Imaging the renal lesion with dual-energy multidetector CT and multi-energy applications in clinical practice: what can it truly do for you?

Journal Article Eur Radiol · October 2016 OBJECTIVE: Many fortuitously detected renal lesions are incompletely characterised at traditional MDCT imaging, thus posing daily challenges to radiologists and referring physicians. There is burgeoning evidence that dual-energy MDCT and multi-energy appli ... Full text Link to item Cite

Adoption of Splenic Enhancement to Time and Trigger the Late Hepatic Arterial Phase During MDCT of the Liver: Proof of Concept and Clinical Feasibility.

Journal Article AJR Am J Roentgenol · August 2016 OBJECTIVE: The purpose of this study was to prospectively investigate the clinical feasibility of adopting splenic enhancement for timing and triggering the acquisition of late hepatic arterial phase images during multiphasic liver MDCT for assessment of h ... Full text Link to item Cite

Regional Mapping of Aortic Wall Stress by Using Deformable, Motion-coherent Modeling based on Electrocardiography-gated Multidetector CT Angiography: Feasibility Study.

Journal Article Radiology · July 2016 Purpose To investigate the feasibility of deformable, motion-coherent modeling based on electrocardiography-gated multidetector computed tomographic (CT) angiography of the thoracic aorta and to evaluate whether quantifiable information on aortic wall stre ... Full text Link to item Cite

Effect of a Noise-Optimized Second-Generation Monoenergetic Algorithm on Image Noise and Conspicuity of Hypervascular Liver Tumors: An In Vitro and In Vivo Study.

Journal Article AJR Am J Roentgenol · June 2016 OBJECTIVE: The purpose of this study is to investigate whether the reduction in noise using a second-generation monoenergetic algorithm can improve the conspicuity of hypervascular liver tumors on dual-energy CT (DECT) images of the liver. MATERIALS AND ME ... Full text Link to item Cite

Can combining triple-arterial phase acquisition with fluoroscopic triggering provide both optimal early and late hepatic arterial phase images during gadoxetic acid-enhanced MRI?

Journal Article J Magn Reson Imaging · May 2016 PURPOSE: To determine whether triple-arterial phase acquisition with fluoroscopic triggering can provide both well-timed early and late hepatic arterial phase (HAP) images more frequently than when using a fixed-time delay during gadoxetic acid-enhanced ma ... Full text Link to item Cite

Virtual Monochromatic Images from Dual-Energy Multidetector CT: Variance in CT Numbers from the Same Lesion between Single-Source Projection-based and Dual-Source Image-based Implementations.

Journal Article Radiology · April 2016 PURPOSE: To determine the variance in virtual monochromatic computed tomography (CT) numbers from the same lesion, comparing the two clinically available dual-energy multidetector CT hardware implementations (single-source projection-based and dual-source ... Full text Link to item Cite

Application of a Novel CT-Based Iliac Artery Calcification Scoring System for Predicting Renal Transplant Outcomes.

Journal Article AJR Am J Roentgenol · February 2016 OBJECTIVE: The objective of our study was to assess whether the degree and distribution of iliac artery calcifications as determined by a CT-based calcium scoring system correlates with outcomes after renal transplant. MATERIALS AND METHODS: A retrospectiv ... Full text Link to item Cite

Determination of contrast media administration to achieve a targeted contrast enhancement in computed tomography.

Journal Article J Med Imaging (Bellingham) · January 2016 Contrast enhancement is a key component of computed tomography (CT) imaging and offers opportunities for optimization. The design and optimization of techniques, however, require orchestration with the scan parameters and, further, a methodology to relate ... Full text Link to item Cite

New Imaging in Gastrointestinal Tract.

Journal Article Gastroenterol Res Pract · 2016 Full text Link to item Cite

Dual-Energy Multidetector Computed Tomography With Iodine Quantification in the Evaluation of Portal Vein Thrombosis: Is It Possible to Discard the Unenhanced Phase?

Journal Article Can Assoc Radiol J · November 2015 Full text Link to item Cite

Effect of radiologists' experience with an adaptive statistical iterative reconstruction algorithm on detection of hypervascular liver lesions and perception of image quality.

Journal Article Abdom Imaging · October 2015 PURPOSE: To prospectively evaluate whether clinical experience with an adaptive statistical iterative reconstruction algorithm (ASiR) has an effect on radiologists' diagnostic performance and confidence for the diagnosis of hypervascular liver tumors, as w ... Full text Link to item Cite

Diagnostic performance of imaging criteria for distinguishing autoimmune cholangiopathy from primary sclerosing cholangitis and bile duct malignancy.

Journal Article Abdom Imaging · October 2015 OBJECTIVE: To determine the diagnostic performance of imaging criteria for distinguishing Ig-G4-associated autoimmune cholangiopathy (IAC) from primary sclerosing cholangitis (PSC) and bile duct malignancy. METHODS: A medical records search between January ... Full text Link to item Cite

High-Pitch Dual-Source MDCT for Imaging of the Thoracoabdominal Aorta: Relationships Among Radiation Dose, Noise, Pitch, and Body Size in a Phantom Experiment and Clinical Study.

Journal Article AJR Am J Roentgenol · October 2015 OBJECTIVE: The purpose of this study was to investigate, both in a phantom experiment and a within-patient clinical study the relationships among radiation dose, image noise, pitch, and body size in MDCT angiography of the thoracoabdominal aorta, with the ... Full text Link to item Cite

Dual energy CT in renal tumors

Chapter · August 19, 2015 Full text Cite

Concordance of hypervascular liver nodule characterization between the organ procurement and transplant network and liver imaging reporting and data system classifications.

Journal Article J Magn Reson Imaging · August 2015 PURPOSE: To determine the rate of agreement between the Organ Procurement and Transplant Network (OPTN) and Liver Imaging Reporting and Data System (LI-RADS) classifications for hypervascular liver nodules at least 1 cm in diameter, and for patient eligibi ... Full text Link to item Cite

Image-guided percutaneous drainage vs. surgical repair of gastrointestinal anastomotic leaks: is there a difference in hospital course or hospitalization cost?

Journal Article Abdom Imaging · June 2015 PURPOSE: To identify differences in hospital course and hospitalization cost when comparing image-guided percutaneous drainage with surgical repair for gastrointestinal anastomotic leaks. MATERIALS AND METHODS: A retrospective IRB-approved search using key ... Full text Link to item Cite

Computer-aided liver volumetry: performance of a fully-automated, prototype post-processing solution for whole-organ and lobar segmentation based on MDCT imaging.

Journal Article Abdom Imaging · June 2015 PURPOSE: To evaluate the performance of a prototype, fully-automated post-processing solution for whole-liver and lobar segmentation based on MDCT datasets. MATERIALS AND METHODS: A polymer liver phantom was used to assess accuracy of post-processing appli ... Full text Link to item Cite

Dual-Energy MDCT for Imaging the Renal Mass.

Journal Article AJR Am J Roentgenol · June 2015 OBJECTIVE: The purpose of this article is to provide the reader with a comprehensive overview of dual-energy MDCT applications for imaging renal masses. CONCLUSION: Dual-energy MDCT has the potential to substantially improve the ability of radiologists to ... Full text Link to item Cite

Emerging applications for ferumoxytol as a contrast agent in MRI.

Journal Article J Magn Reson Imaging · April 2015 Ferumoxytol is an ultrasmall superparamagnetic iron oxide (USPIO) agent initially approved by the Food and Drug Administration (FDA) as an iron replacement therapy for patients with anemia due to chronic renal failure. Recently, ferumoxytol has been invest ... Full text Link to item Cite

Interdependencies of acquisition, detection, and reconstruction techniques on the accuracy of iodine quantification in varying patient sizes employing dual-energy CT.

Journal Article Eur Radiol · March 2015 PURPOSE: To assess the impact of patient habitus, acquisition parameters, detector efficiencies, and reconstruction techniques on the accuracy of iodine quantification using dual-source dual-energy CT (DECT). MATERIALS AND METHODS: Two phantoms simulating ... Full text Link to item Cite

Dual-energy multidetector CT for the characterization of incidental adrenal nodules: diagnostic performance of contrast-enhanced material density analysis.

Journal Article Radiology · February 2015 PURPOSE: To determine whether contrast material-enhanced dual-energy multidetector computed tomography (CT) with material decomposition analysis allows differentiation of adrenal adenomas from nonadenomatous lesions and to compare findings with those of no ... Full text Link to item Cite

Respiratory motion artifact affecting hepatic arterial phase MR imaging with gadoxetate disodium is more common in patients with a prior episode of arterial phase motion associated with gadoxetate disodium.

Journal Article Radiology · January 2015 PURPOSE: To determine, in a dual-center setting, whether patients who experience transient severe motion ( TSM transient severe motion ) in the arterial phase during gadoxetate disodium-enhanced magnetic resonance (MR) imaging are at higher risk for a subs ... Full text Link to item Cite

Dual-Energy Multidetector-Row Computed Tomography of the Hepatic Arterial System: Optimization of Energy and Material-Specific Reconstruction Techniques.

Journal Article J Comput Assist Tomogr · 2015 PURPOSE: To investigate the optimal dual-energy reconstruction technique for the visualization of the hepatic arterial system during dual-energy multidetector computed tomographic (MDCT) angiography of the liver. MATERIALS AND METHODS: Twenty-nine nonconse ... Full text Link to item Cite

Determination of contrast media administration to achieve a targeted contrast enhancement in CT

Conference Progress in Biomedical Optics and Imaging - Proceedings of SPIE · January 1, 2015 Contrast enhancement is a key component of CT imaging and offer opportunities for optimization. The design and optimization of new techniques however requires orchestration with the scan parameters and further a methodology to relate contrast enhancement a ... Full text Cite

CT Appearance of Hepatocellular Carcinoma after Locoregional Treatments: A Comprehensive Review.

Journal Article Gastroenterol Res Pract · 2015 Hepatocellular carcinoma (HCC) is a major health problem worldwide, affecting more than 600,000 new patients per year. Curative treatments are available in a small percentage of patients, while most of them present in stages requiring locoregional treatmen ... Full text Link to item Cite

Iodine quantification to distinguish clear cell from papillary renal cell carcinoma at dual-energy multidetector CT: a multireader diagnostic performance study.

Journal Article Radiology · December 2014 PURPOSE: To investigate whether dual-energy multidetector row computed tomographic (CT) imaging with iodine quantification is able to distinguish between clear cell and papillary renal cell carcinoma ( RCC renal cell carcinoma ) subtypes. MATERIALS AND MET ... Full text Link to item Cite

Dual-energy MDCT in hypervascular liver tumors: effect of body size on selection of the optimal monochromatic energy level.

Journal Article AJR Am J Roentgenol · December 2014 OBJECTIVE: The purpose of this article is to investigate the effect of body size on the selection of optimal monochromatic energy level for maximizing the conspicuity of hypervascular liver tumors during late hepatic arterial phase using dual-energy MDCT. ... Full text Link to item Cite

Nonlinear image blending for dual-energy MDCT of the abdomen: can image quality be preserved if the contrast medium dose is reduced?

Journal Article AJR Am J Roentgenol · October 2014 OBJECTIVE: The objective of this study was to compare the image quality of a dual-energy nonlinear image blending technique at reduced load of contrast medium with a simulated 120-kVp linear blending technique at a full dose during portal venous phase MDCT ... Full text Link to item Cite

Dual-energy multi-detector row CT with virtual monochromatic imaging for improving patient-to-patient uniformity of aortic enhancement during CT angiography: an in vitro and in vivo study.

Journal Article Radiology · September 2014 PURPOSE: To determine whether virtual monochromatic imaging from a dual-energy acquisition can improve patient-to-patient uniformity of aortic enhancement during multi-detector row computed tomographic (CT) angiography. MATERIALS AND METHODS: This retrospe ... Full text Link to item Cite

Impact of dual-energy multi-detector row CT with virtual monochromatic imaging on renal cyst pseudoenhancement: in vitro and in vivo study.

Journal Article Radiology · September 2014 PURPOSE: To investigate whether dual-energy multi-detector row computed tomography (CT) with virtual monochromatic imaging can overcome renal cyst pseudoenhancement in a phantom experiment and a clinical study. MATERIALS AND METHODS: This retrospective sin ... Full text Link to item Cite

Vascular artifact mimicking thrombosis on MR imaging using ferumoxytol as a contrast agent in abdominal vascular assessment.

Journal Article J Vasc Interv Radiol · June 2014 PURPOSE: To describe an artifact that mimics thrombosis when assessing abdominal vasculature on magnetic resonance (MR) imaging using ferumoxytol in patients with contraindications to gadolinium-based contrast agents and to evaluate factors that may contri ... Full text Link to item Cite

Respiratory motion artifact affecting hepatic arterial phase imaging with gadoxetate disodium: examination recovery with a multiple arterial phase acquisition.

Journal Article Radiology · May 2014 PURPOSE: To determine whether the use of a multiple arterial phase imaging technique provides adequate image quality in patients experiencing transient severe motion (TSM) in the arterial phase on abdominal magnetic resonance (MR) images obtained with gado ... Full text Link to item Cite

State of the art: dual-energy CT of the abdomen.

Journal Article Radiology · May 2014 Recent technologic advances in computed tomography (CT)--enabling the nearly simultaneous acquisition of clinical images using two different x-ray energy spectra--have sparked renewed interest in dual-energy CT. By interrogating the unique characteristics ... Full text Link to item Cite

Accuracy of contrast-enhanced dual-energy MDCT for the assessment of iodine uptake in renal lesions.

Journal Article AJR Am J Roentgenol · May 2014 OBJECTIVE: The objective of our study was to assess the accuracy of iodine-related attenuation and iodine quantification as imaging biomarkers of iodine uptake in renal lesions on a single-phase nephrographic image with dual-energy MDCT. MATERIALS AND METH ... Full text Link to item Cite

Adrenal glands

Chapter · May 1, 2014 The adrenal glands can develop a myriad of abnormalities, which can be fundamentally differentiated into benign or malignant lesions having either hyperfunction or non-hyperfunction (i.e., non-function) [1, 2]. Functioning lesions typically secrete hormona ... Full text Cite

Hepatocellular carcinoma enhancement on contrast-enhanced CT and MR imaging: response assessment after treatment with sorafenib: preliminary results.

Journal Article Radiol Med · April 2014 PURPOSE: This study was undertaken to compare response evaluation criteria in solid tumours (RECIST) 1.1 and modified RECIST (mRECIST) in patients with unresectable hepatocellular carcinoma (HCC) on sorafenib, and to describe HCC enhancement changes before ... Full text Link to item Cite

Dual energy MDCT assessment of renal lesions: an overview.

Journal Article Eur Radiol · February 2014 With the expansion of cross-sectional imaging, the number of renal lesions that are incidentally discovered has increased. Multidetector CT (MDCT) is the investigation of choice for characterising and staging renal lesions. Although a definitive diagnosis ... Full text Link to item Cite

Focal lesions in cirrhotic liver: what else beyond hepatocellular carcinoma?

Journal Article Diagn Interv Radiol · 2014 Detection and characterization of focal lesions in the cirrhotic liver may pose a diagnostic dilemma. Several benign and malignant lesions may be found in a cirrhotic liver along with hepatocellular carcinoma (HCC), and may exhibit typical or atypical imag ... Full text Link to item Cite

Multimodality approach to detection and characterization of hepatic hemangiomas

Chapter · January 1, 2014 Hemangiomas are the most common benign hepatic tumor and represent a common incidental finding on routine imaging examinations of the liver. The majority of hemangiomas demonstrate classical imaging findings on grayscale ultrasound (US), multidetector-row ... Full text Cite

Clinical impact of an adaptive statistical iterative reconstruction algorithm for detection of hypervascular liver tumours using a low tube voltage, high tube current MDCT technique.

Journal Article Eur Radiol · December 2013 OBJECTIVES: To investigate the impact of an adaptive statistical iterative reconstruction (ASiR) algorithm on diagnostic accuracy and confidence for the diagnosis of hypervascular liver tumours, as well as the reader's perception of image quality, using a ... Full text Link to item Cite

Cirrhosis

Chapter · November 1, 2013 Cirrhosis is a pathologic and clinical entity that occurs following repeated hepatocyte damage and is characterized by extensive fibrosis and innumerable regenerative nodules replacing the normal liver parenchyma. Ultimately, the process can lead to liver ... Full text Cite

FDG-PET/CT characterization of adrenal nodules: diagnostic accuracy and interreader agreement using quantitative and qualitative methods.

Journal Article Acad Radiol · August 2013 PURPOSE: To determine interreader agreement and diagnostic accuracy across varying levels of reader experience using qualitative and quantitative methods of evaluating adrenal nodules using ((18)F)-fluorodeoxyglucose-positron emission tomography/computed t ... Full text Link to item Cite

Pancreas

Chapter · May 1, 2013 Imaging of the pancreas is challenging because of its anatomic location in the retroperitoneum and its intricate relationship with major blood vessels and bowel [1]. In the United States, acute pancreatitis, chronic pancreatitis, and pancreatic cancer are ... Full text Cite

Precision of iodine quantification in hepatic CT: effects of iterative reconstruction with various imaging parameters.

Journal Article AJR Am J Roentgenol · May 2013 OBJECTIVE: The objective of this study was to evaluate the feasibility of using iterative reconstructions in hepatic CT to improve the precision of Hounsfield unit quantification, which is the degree to which repeated measurements under unchanged condition ... Full text Link to item Cite

Adrenal lesions: spectrum of imaging findings with emphasis on multi-detector computed tomography and magnetic resonance imaging.

Journal Article J Clin Imaging Sci · 2013 The adrenal gland is a common site of a large spectrum of abnormalities like primary tumors, hemorrhage, metastases, and enlargement of the gland from external hormonal stimulation. Most of these lesions represent nonfunctioning adrenal adenomas and thus w ... Full text Link to item Cite

Dual-energy CT applications in the abdomen.

Journal Article AJR Am J Roentgenol · November 2012 OBJECTIVE: The purpose of this article is to give a brief overview of the technical background of dual-energy CT (DECT) imaging and to review various DECT applications in the abdomen that are currently available for clinical practice. In a review of the re ... Full text Link to item Cite

Hepatic hemangiomas: difference in enhancement pattern on 3T MR imaging with gadobenate dimeglumine versus gadoxetate disodium.

Journal Article Eur J Radiol · October 2012 PURPOSE: To compare intraindividual differences in enhancement pattern of hepatic hemangiomas between gadobenate dimeglumine (Gd-BOPTA) and gadoxetate disodium (Gd-EOB-DTPA)-enhanced 3T MR imaging. MATERIALS AND METHODS: This is a HIPAA-compliant, IRB-appr ... Full text Link to item Cite

Enhancement pattern of small hepatocellular carcinoma (HCC) at contrast-enhanced US (CEUS), MDCT, and MRI: intermodality agreement and comparison of diagnostic sensitivity between 2005 and 2010 American Association for the Study of Liver Diseases (AASLD) guidelines.

Journal Article Eur J Radiol · September 2012 OBJECTIVE: To evaluate agreement between contrast-enhanced ultrasound (CEUS), multi-detector row computed tomography (MDCT) and magnetic resonance imaging (MRI) for the assessment of typical and atypical enhancement patterns of small hepatocellular carcino ... Full text Link to item Cite

Radiation dose reduction in abdominal computed tomography during the late hepatic arterial phase using a model-based iterative reconstruction algorithm: how low can we go?

Journal Article Invest Radiol · August 2012 Featured Publication OBJECTIVE: The aim of this study was to compare the image quality of abdominal computed tomography scans in an anthropomorphic phantom acquired at different radiation dose levels where each raw data set is reconstructed with both a standard convolution fil ... Full text Link to item Cite

Characterization of adrenal nodules with dual-energy CT: can virtual unenhanced attenuation values replace true unenhanced attenuation values?

Journal Article AJR Am J Roentgenol · April 2012 Featured Publication OBJECTIVE: The purpose of our study was to investigate whether virtual unenhanced adrenal nodule attenuation values can replace true noncontrast attenuation values. MATERIALS AND METHODS: Twenty-three incidentally discovered adrenal nodules (19 adenomas an ... Full text Link to item Cite

Imaging findings of liver resection using a bipolar radiofrequency electrosurgical device--initial observations.

Journal Article Eur J Radiol · April 2012 OBJECTIVE: To assess contrast-enhanced US (CEUS), computed tomography (CT) and magnetic resonance (MR) imaging findings and serial changes of the treated area at follow-up in patients who underwent liver resection using a bipolar radiofrequency electrosurg ... Full text Link to item Cite

Effect of tumor size and tumor-to-liver contrast of hypovascular liver tumors on the diagnostic performance of hepatic CT imaging.

Journal Article Invest Radiol · March 2012 OBJECTIVE: To assess the effect of tumor size and tumor-to-liver contrast of simulated hypovascular liver tumors on the diagnostic accuracy of hepatic computed tomography (CT). MATERIALS AND METHODS: This retrospective study was approved by the institution ... Full text Link to item Cite

Effect of tumor size and tumor-to-liver contrast of hypovascular liver tumors on the diagnostic performance of hepatic CT imaging.

Journal Article Investigative radiology · March 1, 2012 To assess the effect of tumor size and tumor-to-liver contrast of simulated hypovascular liver tumors on the diagnostic accuracy of hepatic computed tomography (CT). This retrospective study was approved by the institutional review board, and informed cons ... Cite