Laura Jean Havrilesky

Journal Article Gynecol Oncol · December 2025 OBJECTIVE: To compare cost-effectiveness of targeted therapeutic strategies for non-Hispanic Black (NHB) and non-Hispanic White (NHB) patients with newly diagnosed, advanced-stage endometrial cancer. METHODS: A Markov-based cost-utility model using a third ... Full text Link to item Cite

Preferences of BRCA mutation carriers for attributes of risk-reducing surgical options for breast and ovarian cancer.

Journal Article Cancer · November 15, 2025 BACKGROUND: Risk-reducing surgeries are the most effective strategies for cancer prevention in patients with germline pathogenic variants in the BRCA1/BRCA2 genes; these surgeries are associated with early menopause, loss of childbearing potential, and cos ... Full text Link to item Cite

Gynecologic oncology fellowship trends: Supply outpacing demand, geographical maldistribution.

Journal Article Gynecol Oncol · November 2025 OBJECTIVE: To examine the trends and geographic distribution of US GO fellowship programs over time and analyze GO specific procedures by regions. METHODS: Using the publicly available data from the NRMP, the number of GO fellowship programs and positions ... Full text Link to item Cite

Performance of ultrasound and rates of guideline-concordant care in a diverse postmenopausal bleeding cohort.

Journal Article Am J Obstet Gynecol · October 10, 2025 BACKGROUND: Professional society guidelines endorse the use of ultrasound to evaluate an initial episode of postmenopausal bleeding, with endometrial sampling reserved for patients with an endometrial thickness exceeding 4 mm. However, the data supporting ... Full text Link to item Cite

Survival After Fertility-Preserving Hormonal Therapy vs Hysterectomy for Early-Stage Endometrial Cancer.

Journal Article JAMA Oncol · October 1, 2025 IMPORTANCE: As the number of young women with early-stage endometrial cancer is increasing, there is growing interest in use of progesterone-based therapy to allow fertility preservation. OBJECTIVE: To ascertain the long-term survival of premenopausal wome ... Full text Link to item Cite

Trends in uterine cancer incidence and mortality: insights from a natural history model.

Journal Article J Natl Cancer Inst · September 1, 2025 BACKGROUND: Uterine cancer incidence and mortality are increasing, with concomitant disparities in outcomes between racial groups. Natural history modeling can evaluate risk factors, predict future trends, and simulate approaches to reducing mortality and ... Full text Link to item Cite

Relationship between abnormal p53 expression and high-risk histology in endometrial cancers and living in proximity to hog concentrated animal feeding operations in North Carolina.

Journal Article Gynecol Oncol Rep · August 2025 OBJECTIVE: Prior research demonstrated a 2.27-fold increase in uterine cancer mortality among North Carolinians living near hog concentrated animal feeding operations (CAFOs). Endometrial cancer (EC) accounts for 90% of uterine cancer cases. Mutation and a ... Full text Link to item Cite

Projected Trends in the Incidence and Mortality of Uterine Cancer in the United States.

Journal Article Cancer Epidemiol Biomarkers Prev · July 1, 2025 BACKGROUND: To develop a natural history model for uterine cancer calibrated to population-based incidence and mortality data to project future trends in the disease through 2050. METHODS: We developed a state-transition microsimulation model of uterine ca ... Full text Link to item Cite

A pilot study investigating the effect of pembrolizumab on the tumoral immunoprofile of newly diagnosed mullerian cancers.

Journal Article Gynecol Oncol Rep · June 2025 OBJECTIVE: This pilot window of opportunity study was conducted to assess feasibility, toxicity, and changes in immune parameters in response to one dose of the PD-1 inhibitor, pembrolizumab, in patients newly diagnosed with mullerian epithelial cancers. M ... Full text Link to item Cite

Quality for All: Clinical Trial Enrollment and End-of-Life Care in Solid and Hematologic Malignancies.

Journal Article Cancer Med · May 2025 BACKGROUND: Patients with incurable cancer deserve quality end-of-life (EOL) care. Despite established EOL quality metrics, many patients receive aggressive EOL care with limited goals of care (GOC) documentation. Concurrently, clinical trials are critical ... Full text Link to item Cite

Too Much of a Good Thing? Projecting the Need for Gynecologic Oncologists Over the Next 20 Years

Journal Article Obstetrical and Gynecological Survey · May 1, 2025 There are currently 71 gynecologic oncology fellowship programs in the United States, with a rapid increase in the number of programs occurring within the last 5 years. Additionally, accreditation for these fellowships has shifted from the American Board o ... Full text Cite

In Reply.

Journal Article Obstet Gynecol · April 1, 2025 Full text Link to item Cite

Response to the letter to the editor - Quality and accuracy of physician and chatbot responses to clinical questions in gynecologic oncology: Correspondence.

Journal Article Gynecol Oncol Rep · April 2025 Full text Link to item Cite

Ultrasound-based versus immediate biopsy-based management of postmenopausal bleeding in non-Hispanic Black and non-Hispanic White individuals.

Journal Article Gynecol Oncol · March 2025 BACKGROUND: Ultrasound-based evaluation of endometrial thickness to rule out endometrial cancer in patients with postmenopausal bleeding (PMB) is not sufficiently validated in the non-Hispanic Black (NHB) population. Differences in ultrasound performance b ... Full text Link to item Cite

Surgical Deescalation Within Gynecologic Oncology.

Journal Article JAMA Netw Open · January 2, 2025 IMPORTANCE: The goal of surgical deescalation is to minimize tissue damage, enhance patient outcomes, and reduce the adverse effects often associated with extensive or traditional surgical procedures. This shift toward less invasive techniques has the pote ... Full text Link to item Cite

Screening for Bacterial Vaginosis Prior to Delivery: A Cost-Effectiveness Study.

Journal Article Am J Perinatol · January 2025 OBJECTIVE: The objective of this study was to compare the cost and effectiveness of three strategies for screening and/or treating bacterial vaginosis (BV) during pregnancy prior to delivery: (1) the current standard of care was neither test nor treat for ... Full text Link to item Cite

Optimization of Timing for Risk-Reducing Salpingectomy and Oophorectomy.

Journal Article Obstet Gynecol · January 1, 2025 ClinicalTrials.gov , NCT04251052. ... Full text Link to item Cite

Transcutaneous Electric Nerve Stimulation for Analgesia During Outpatient Endometrial Biopsy: A Randomized Controlled Trial.

Journal Article Obstet Gynecol · January 1, 2025 OBJECTIVE: To evaluate whether transcutaneous electric nerve stimulation (TENS) decreases pain at the time of outpatient endometrial biopsy. METHODS: We conducted a randomized, double-blind trial of active TENS compared with placebo TENS at the time of end ... Full text Link to item Cite

The Role of Sleep Apnea in Postoperative Neurocognitive Disorders Among Older Noncardiac Surgery Patients: A Prospective Cohort Study.

Journal Article Anesth Analg · January 1, 2025 BACKGROUND: Obstructive sleep apnea is associated with increased dementia risk, yet its role in postoperative neurocognitive disorders is unclear. Here, we studied whether the severity of untreated obstructive sleep apnea is associated with the severity of ... Full text Link to item Cite

Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities

Journal Article Npj Precision Oncology · December 1, 2024 We performed a deep proteogenomic analysis of bulk tumor and laser microdissection enriched tumor cell populations from high-grade serous ovarian cancer (HGSOC) tissue specimens spanning a broad spectrum of purity. We identified patients with longer progre ... Full text Cite

Author Correction: Proteogenomic analysis of enriched HGSOC tumor epithelium identifies prognostic signatures and therapeutic vulnerabilities (npj Precision Oncology, (2024), 8, 1, (68), 10.1038/s41698-024-00519-8)

Journal Article Npj Precision Oncology · December 1, 2024 Correction to: npj Precision Oncologyhttps://doi.org/10.1038/s41698-024-00519-8, published online 13 March 2024 In the original version of this article, the wrong file was inadvertently supplied for Supplementary Data 15. The original article has been corr ... Full text Cite

Adjuvant therapy and recurrence risk in non-myoinvasive high-grade (stage IC) endometrial cancer: A systematic review and meta-analysis.

Journal Article Gynecol Oncol · December 2024 OBJECTIVE: To summarize practice patterns and outcomes among patients with non-myoinvasive high-grade (formerly stage IA, now stage IC) endometrial cancer. METHODS: We conducted a systematic search using MEDLINE, Embase, Cochrane, Web of Science, and Clini ... Full text Link to item Cite

Too much of a good thing? Projecting the need for gynecologic oncologists over the next 20 years.

Journal Article Gynecol Oncol · December 2024 OBJECTIVE: To estimate the effect of growth in gynecologic oncology fellowships in the United States on surgical volume for trainees and practicing gynecologic oncologists over the next 20 years. METHODS: Using 2010-2019 age-specific gynecologic cancer inc ... Full text Link to item Cite

Weight-loss therapy in patients with obesity with endometrial intraepithelial neoplasia and uterine cancer.

Journal Article Gynecol Oncol · November 2024 OBJECTIVE: Although obesity is an important risk factor for endometrial intraepithelial neoplasia (EIN) and uterine cancer, little is known about the trends in use of weight-loss therapy for patients with obesity with EIN and uterine cancer. We examined th ... Full text Link to item Cite

The doc versus the bot: A pilot study to assess the quality and accuracy of physician and chatbot responses to clinical questions in gynecologic oncology.

Journal Article Gynecol Oncol Rep · October 2024 Artificial intelligence (AI) applications to medical care are currently under investigation. We aimed to evaluate and compare the quality and accuracy of physician and chatbot responses to common clinical questions in gynecologic oncology. In this cross-se ... Full text Link to item Cite

Development of a Predictive Model for Emergency Department Utilization and Unanticipated Hospital Admission in Patients Receiving Cancer Treatment for Solid Tumor Malignancies

Conference JCO Oncology Practice · September 1, 2024 PURPOSEUnanticipated health care resource utilization, in the form of either emergency department utilization (EDU) or hospital admission (HA), may be an indicator of lower-quality cancer care. The objective of this study was to develop a predictive model ... Full text Cite

Moving the needle: Quality improvement strategies to achieve guideline-concordant care of obstetric patients with severe hypertension.

Journal Article Pregnancy Hypertens · September 2024 OBJECTIVES: To improve timely treatment and follow-up of birthing individuals with severe hypertension. STUDY DESIGN: A quality improvement (QI) initiative was implemented at an academic tertiary care center in the United States of America for individuals ... Full text Link to item Cite

Trends in uterine cancer incidence in the United States: The contribution of age, period and cohort effects.

Journal Article Gynecol Oncol · August 2024 OBJECTIVE: In the U.S., uterine cancer incidence is rising, with racial and ethnic minorities experiencing the largest increases. We performed age-period-cohort analyses using novel methods to examine the contribution of age at diagnosis (age), year of dia ... Full text Link to item Cite

ACO leakage among gynecologic cancer patients: Incidence, predictors, and impact on annual Medicare expenditure.

Journal Article Gynecol Oncol · August 2024 OBJECTIVE: To examine patterns of Accountable Care Organizations (ACO) leakage, the receipt of healthcare by ACO-assigned patients from institutions outside assigned ACO network, among patients with gynecologic cancer. ACO leakage was estimated as rates of ... Full text Link to item Cite

Ensuring safe and equitable discharge: a quality improvement initiative for individuals with hypertensive disorders of pregnancy.

Journal Article BMJ Qual Saf · May 17, 2024 OBJECTIVE: To improve timely and equitable access to postpartum blood pressure (BP) monitoring in individuals with hypertensive disorders of pregnancy (HDP). METHODS: A quality improvement initiative was implemented at a large academic medical centre in th ... Full text Open Access Link to item Cite

Cryocompression to Reduce Peripheral Neuropathy in Gynecologic Cancer: A Randomized Controlled Trial

Journal Article Obstetrical and Gynecological Survey · May 1, 2024 Full text Cite

Role of endometrial sampling to differentiate between advanced endometrial versus ovarian malignancy: retrospective cohort study.

Journal Article Int J Gynecol Cancer · April 1, 2024 OBJECTIVE: Distinguishing between advanced stage endometrial and ovarian cancer at diagnosis can be challenging, especially when patients do not present with abnormal uterine bleeding. Given emerging systemic therapies specific for ovarian versus endometri ... Full text Link to item Cite

Randomized Comparison of Electronic Health Record Alert Types in Eliciting Responses about Prognosis in Gynecologic Oncology Patients.

Journal Article Appl Clin Inform · March 2024 OBJECTIVES: To compare the ability of different electronic health record alert types to elicit responses from users caring for cancer patients benefiting from goals of care (GOC) conversations. METHODS: A validated question asking if the user would be su ... Full text Link to item Cite

Development and testing of patient-centered education about hormone replacement therapy for women at high genetic risk of breast and ovarian cancer.

Journal Article Gynecol Oncol · February 2024 OBJECTIVE: In this study, we aimed to develop education to assist BRCA mutation carriers in making informed decisions about HRT in the context of risk-reducing surgery, while simultaneously clarifying their treatment-specific values and reducing decisional ... Full text Link to item Cite

An Obstetrician-Gynecologist's Review of Hernias: Risk Factors, Diagnosis, Prevention, and Repair

Journal Article Obstetrical and Gynecological Survey · February 1, 2024 Full text Cite

Long-term survival outcomes for hormonal therapy in premenopausal patients with clinical stage I endometrial cancer

Conference Journal of Clinical Oncology · January 1, 2024 Background: As the number of young women with early-stage endometrial cancer is increasing, there is growing interest in use of progesterone-based therapy to allow fertility preservation. To date, there is a paucity of data on the safety and long-term outc ... Full text Cite

PALLIATIVE SURGERY FOR OVARIAN CANCER

Chapter · January 1, 2024 The majority of patients with advanced-stage ovarian cancer will recur and ultimately succumb to their disease. Interventions such as secondary cytoreduction, salvage chemotherapy, and clinical trials may prolong life but are almost never curative. The sur ... Full text Cite

Deep learning-based segmentation of multisite disease in ovarian cancer.

Journal Article Eur Radiol Exp · December 7, 2023 PURPOSE: To determine if pelvic/ovarian and omental lesions of ovarian cancer can be reliably segmented on computed tomography (CT) using fully automated deep learning-based methods. METHODS: A deep learning model for the two most common disease sites of h ... Full text Link to item Cite

Cryocompression to Reduce Peripheral Neuropathy in Gynecologic Cancer: A Randomized Controlled Trial.

Journal Article Obstet Gynecol · December 1, 2023 OBJECTIVE: To investigate the efficacy of cryocompression therapy to prevent chemotherapy-induced peripheral neuropathy. METHODS: This single-institution, randomized, self-controlled trial of cryocompression enrolled gynecologic cancer patients planned for ... Full text Link to item Cite

Radical hysterectomy case volume and cervical cancer treatment in the era of COVID-19: A multi-site analysis of National Cancer Institute-designated Comprehensive Cancer Centers.

Journal Article Gynecol Oncol · December 2023 OBJECTIVE: To compare radical hysterectomy case volume, cancer stage, and biopsy-to-treatment time of invasive cervical cancer diagnosed before and after onset of the COVID-19 pandemic. METHODS: In a multi-institution retrospective cohort study conducted a ... Full text Link to item Cite

Efficacy of cyclin-dependent kinase 4/6 inhibitors in combination with hormonal therapy in patients with recurrent granulosa cell tumor of the ovary: A case series.

Journal Article Gynecol Oncol Rep · December 2023 Cyclin-dependent kinase inhibitors are approved in combination with hormonal therapy for treatment of hormone receptor expressing breast cancers. Activity in hormone receptor expressing gynecologic cancers has been postulated. Granulosa cell tumor of the o ... Full text Link to item Cite

Geographic variation in the rate and route of hysterectomy for benign disease in the USA: A retrospective cross-sectional study.

Journal Article BJOG : an international journal of obstetrics and gynaecology · November 2023 ObjectivesTo describe population rate of hysterectomy for benign disease in the USA, including geographic variation across states and Hospital Service Areas (HSAs; areas defined by common patient flows to healthcare facilities).DesignCros ... Full text Cite

Outcomes and Complications for Concurrent Hernia Repair Among Women Undergoing Hysterectomy.

Journal Article Obstet Gynecol · November 1, 2023 OBJECTIVE: To assess whether concurrent hernia repair at time of hysterectomy is associated with increased complications. METHODS: In this retrospective cohort study, patients who underwent hysterectomy and hysterectomy with concurrent hernia repair were q ... Full text Link to item Cite

Intraluminal tumor cells and prognostic accuracy of endometrial cancer stage criteria: A multi-institution study.

Journal Article Gynecol Oncol · November 2023 OBJECTIVE: Endometrial cancer stage is a strong prognostic factor; however, the current stage classification does not incorporate transtubal spread as determined by intraluminal tumor cells (ILTCs). We examined relationships between ILTCs and survival outc ... Full text Link to item Cite

An obstetrician-gynecologist's review of hernias: risk factors, diagnosis, prevention, and repair.

Journal Article Am J Obstet Gynecol · September 2023 Management of obstetrical and gynecologic patients with hernias poses challenges to providers. Risks for hernia development include well-described factors that impair surgical wound healing and increase abdominal pressure. Among the diverse populations car ... Full text Link to item Cite

The Clinical Trial Conundrum for Gynecologic Cancers.

Journal Article Obstet Gynecol · September 1, 2023 Full text Link to item Cite

Universal thromboprophylaxis in ovarian cancer patients before and after surgery?

Journal Article Gynecol Oncol · September 2023 Full text Link to item Cite

Guidelines for goals of care discussions in patients with gynecologic cancer.

Journal Article Gynecol Oncol · July 2023 This article represents a distillation of literature to provide guidance for goals of care discussions with patients who have gynecologic malignancies. As clinicians who provide surgical care, chemotherapy, and targeted therapeutics, gynecologic oncology c ... Full text Link to item Cite

Treatments and outcomes in high-risk gestational trophoblastic neoplasia: A systematic review and meta-analysis.

Journal Article BJOG · April 2023 BACKGROUND: High-risk gestational trophoblastic neoplasia (GTN) is rare and treated with diverse approaches. Limited published institutional data has yet to be systematically reviewed. OBJECTIVES: To compile global high-risk GTN (prognostic score ≥7) cohor ... Full text Link to item Cite

A Pilot Study of a Screening Program for Human Papillomavirus-Related Squamous Intraepithelial Lesion and Malignancy in Gynecologic Oncology Patients.

Journal Article J Low Genit Tract Dis · April 1, 2023 OBJECTIVE: Human papillomavirus (HPV)-related squamous intraepithelial lesion (SIL) or malignancy is associated with a significantly increased risk of second-site SIL or malignancy. The primary objective of this study was to determine the feasibility and a ... Full text Link to item Cite

BAP1 Tumor Predisposition Syndrome Presenting as a Recurrent Ovarian Sex Cord-Stromal Tumor.

Journal Article Int J Gynecol Pathol · January 1, 2023 The BRCA1-associated protein 1 ( BAP1 ) gene encodes a tumor suppressor that functions as a ubiquitin hydrolase involved in DNA damage repair. BAP1 germline mutations are associated with increased risk of multiple solid malignancies, including mesothelioma ... Full text Link to item Cite

Implementing guidelines for risk-stratified thromboprophylaxis among gynecologic oncology patients: A quality improvement initiative.

Journal Article Gynecol Oncol · January 2023 OBJECTIVE(S): Risk-stratified thromboprophylaxis is recommended for oncology patients with a Khorana risk score (KS) ≥ 2 receiving cancer-directed therapy. We describe a quality improvement (QI) initiative designed to increase adherence to thromboprophylax ... Full text Link to item Cite

Cost-effectiveness of management strategies for patients with recurrent ovarian cancer and inoperable malignant bowel obstruction.

Journal Article Gynecol Oncol · December 2022 OBJECTIVES: Patients with recurrent platinum-resistant ovarian cancer often present with inoperable malignant bowel obstruction (MBO) from a large burden of abdominal disease. Interventions such as total parenteral nutrition (TPN) and chemotherapy may be u ... Full text Link to item Cite

Telemedicine and gynecologic oncology: caring for patients remotely during a global pandemic

Conference Ajog Global Reports · November 1, 2022 BACKGROUND: Telemedicine uses technology to deliver medical care remotely and has been shown to provide similar patient satisfaction and care outcomes compared with in-person visits. OBJECTIVE: This study aimed to assess the gynecologic oncology patient te ... Full text Cite

Understanding the needs and perspectives of ovarian cancer patients when considering PARP inhibitor maintenance therapy: Findings from two online community events.

Journal Article Gynecol Oncol Rep · October 2022 OBJECTIVE: The online environment is an ideal setting to understand how many women seek, receive, and understand information about cancer treatment. The purpose of this study was to understand women's needs and information-seeking around Poly ADP ribose po ... Full text Link to item Cite

Improving Risk Assessment for Metastatic Disease in Endometrioid Endometrial Cancer Patients Using Molecular and Clinical Features: An NRG Oncology/Gynecologic Oncology Group Study.

Journal Article Cancers (Basel) · August 23, 2022 Objectives: A risk assessment model for metastasis in endometrioid endometrial cancer (EEC) was developed using molecular and clinical features, and prognostic association was examined. Methods: Patients had stage I, IIIC, or IV EEC with tumor-derived RNA- ... Full text Link to item Cite

Ridiculously good writing: How to write like a pro and publish like a boss.

Journal Article Gynecol Oncol Rep · August 2022 Full text Link to item Cite

Development and Validation of a Model for Opioid Prescribing Following Gynecological Surgery.

Journal Article JAMA Netw Open · July 1, 2022 IMPORTANCE: Overprescription of opioid medications following surgery is well documented. Current prescribing models have been proposed in narrow patient populations, which limits their generalizability. OBJECTIVE: To develop and validate a model for predic ... Full text Open Access Link to item Cite

Malnutrition as a Risk Factor for Post-Operative Morbidity in Gynecologic Cancer: Analysis Using a National Surgical Outcomes Database

Other Obstetrical and Gynecological Survey · July 1, 2022 Full text Cite

Cost-effectiveness of bacteriuria screening before urogynecologic surgery.

Journal Article Am J Obstet Gynecol · June 2022 BACKGROUND: Currently, there is controversy over who requires preoperative screening for bacteriuria in the urogynecologic population and whether treating asymptomatic bacteriuria reduces postoperative urinary tract infection rates. OBJECTIVE: To evaluate ... Full text Link to item Cite

Malnutrition as a risk factor for post-operative morbidity in gynecologic cancer: Analysis using a national surgical outcomes database.

Journal Article Gynecol Oncol · May 2022 OBJECTIVE: To assess, using a national surgical outcomes database, the association of various malnutrition definitions with post-operative morbidity in three gynecologic malignancies. METHODS: Patients undergoing resection of ovarian, uterine, or cervical ... Full text Link to item Cite

Out-of-network bills among privately insured patients undergoing hysterectomy.

Journal Article Am J Obstet Gynecol · April 2022 BACKGROUND: In recent years, the issue of out-of-network billing for privately insured patients has been highlighted as a source of unexpected out-of-pocket charges for patients, even in the setting of an in-network primary surgeon. The Congress recently p ... Full text Link to item Cite

Reducing non-surgical readmissions on a gynecologic oncology service.

Journal Article Gynecol Oncol · April 2022 OBJECTIVE: To assess the effects of a quality improvement (QI) initiative designed to reduce non-surgical readmissions on a gynecologic oncology service. METHODS: A two-phase QI initiative was implemented on an inpatient gynecologic oncology service to red ... Full text Link to item Cite

Evaluation of Surgical Morbidity After Hysterectomy During an Obesity Epidemic.

Journal Article Obstet Gynecol · April 1, 2022 OBJECTIVE: To assess 30-day outcomes for hysterectomy by body mass index (BMI) classification and estimate trends in 30-day outcomes by BMI over time. METHODS: This is a retrospective cohort study of patients older than age 18 years undergoing hysterectomy ... Full text Link to item Cite

Catastrophic health expenditures, insurance churn, and nonemployment among gynecologic cancer patients in the United States.

Journal Article Am J Obstet Gynecol · March 2022 BACKGROUND: In recent years, there has been growing recognition of the financial burden of severe illness, including associations with higher rates of nonemployment, uninsurance, and catastrophic out-of-pocket health spending. Patients with gynecologic can ... Full text Link to item Cite

Opportunities to Advance the Delivery of High-Quality, Goal-Concordant End-of-Life Care in Ovarian Cancer.

Journal Article JCO Oncol Pract · March 2022 Full text Link to item Cite

Distress screening in endometrial cancer leads to disparity in referral to support services.

Journal Article Gynecol Oncol · March 2022 OBJECTIVES: Racial disparities in survival from endometrial cancer (EC) are well known. Cancer distress has also been associated with worse clinical outcomes. We characterized the association between race/ethnicity, patient distress reported on the Nationa ... Full text Link to item Cite

Promoting timely goals of care conversations between gynecologic cancer patients at high-risk of death and their providers.

Journal Article Gynecol Oncol · February 2022 OBJECTIVE: We designed a multi-faceted intervention to increase the rate of outpatient goals of care (GOC) conversations in women with gynecologic cancers who are at high-risk of death. METHODS AND MATERIALS: A multidisciplinary team developed an education ... Full text Link to item Cite

Standardization of caregiver and nursing perioperative care on gynecologic oncology wards in a resource-limited setting.

Journal Article Gynecol Oncol Rep · February 2022 INTRODUCTION: In Kampala, Uganda, there is a strong cultural practice for patients to have designated caregivers for the duration of hospitalization. At the same time, nursing support is limited. This quality improvement project aimed to standardize caregi ... Full text Link to item Cite

A Qualitative Assessment of Patient Experience following Systematic Implementation of Goals of Care Conversations in the Ambulatory Gynecologic Oncology Setting.

Journal Article Palliat Med Rep · 2022 OBJECTIVE: Although skilled goals of care (GOC) conversations are known to reduce aggressive futile end-of-life care, they have not been widely implemented nor standardized in the care of gynecologic malignancies. Clinicians express concern regarding patie ... Full text Link to item Cite

Adjuvant treatment and outcomes for patients with stage IIIA grade 1 endometrioid endometrial cancer.

Journal Article Int J Gynecol Cancer · December 2021 OBJECTIVE: The role and type of adjuvant therapy for patients with International Federation of Gynecology and Obstetrics (FIGO) stage IIIA grade 1 endometrioid endometrial adenocarcinoma are controversial. This retrospective cohort study aimed to determine ... Full text Link to item Cite

Patient Preferences for Outcomes Following DCIS Management Strategies: A Discrete Choice Experiment.

Journal Article JCO Oncol Pract · November 2021 PURPOSE: Ductal carcinoma in situ (DCIS), a nonobligate precursor of breast cancer, is often aggressively managed with multimodal therapy. However, there is limited research on patients' preferences for trade-offs among treatment-related outcomes such as b ... Full text Link to item Cite

Surveillance for gestational trophoblastic neoplasia following molar pregnancy: a cost-effectiveness analysis.

Journal Article Am J Obstet Gynecol · November 2021 BACKGROUND: Historically, published guidelines for care after molar pregnancy recommended monitoring human chorionic gonadotropin levels for the development of gestational trophoblastic neoplasia until normal and then for 6 months after the first normal hu ... Full text Link to item Cite

Neoadjuvant chemotherapy for advanced stage endometrial cancer: A systematic review.

Journal Article Gynecol Oncol Rep · November 2021 OBJECTIVE: While primary cytoreductive surgery (PCS) is considered the standard of care for women who present with stage IV endometrial cancer, neoadjuvant chemotherapy (NACT) followed by interval cytoreductive surgery (ICS) has emerged as an alternative t ... Full text Link to item Cite

Histopathology after lidocaine/prilocaine cream administration for vulvar biopsy.

Journal Article J Cutan Pathol · October 2021 BACKGROUND: Case series have described disruptive histopathologic changes following lidocaine/prilocaine cream anesthetic for biopsies. METHODS: A study of histopathologic changes was performed following a randomized trial comparing topical lidocaine/prilo ... Full text Link to item Cite

Real-world treatment patterns of maintenance therapy in platinum-sensitive recurrent ovarian cancer.

Journal Article Gynecol Oncol · October 2021 OBJECTIVES: The clinical utility of maintenance therapy (MT) for patients with platinum-sensitive recurrent ovarian cancer has been validated in several clinical trials. We assessed "real-world" treatment patterns using an electronic health record (EHR) da ... Full text Link to item Cite

Primary cytoreductive surgery for advanced stage endometrial cancer: a systematic review and meta-analysis.

Journal Article Am J Obstet Gynecol · September 2021 OBJECTIVE: Endometrial cancer uncommonly presents at an advanced stage and little prospective evidence exists to guide the management thereof. We aimed to summarize the evidence about primary cytoreductive surgery in the treatment of advanced stage endomet ... Full text Link to item Cite

Associations of Insurance Churn and Catastrophic Health Expenditures With Implementation of the Affordable Care Act Among Nonelderly Patients With Cancer in the United States.

Journal Article JAMA Netw Open · September 1, 2021 IMPORTANCE: Health insurance coverage is dynamic in the United States, potentially changing from month to month. The Patient Protection and Affordable Care Act (ACA) aimed to stabilize markets and reduce financial burden, particularly among those with pree ... Full text Link to item Cite

Cost-Effectiveness of Venous Thromboembolism Prophylaxis During Neoadjuvant Chemotherapy for Ovarian Cancer.

Journal Article JCO Oncol Pract · August 2021 PURPOSE: Two recent clinical trials have demonstrated that direct oral anticoagulants (DOACs) are effective as venous thromboembolism (VTE) prophylaxis in patients with moderate-to-high risk ambulatory cancer initiating chemotherapy. Patients with advanced ... Full text Link to item Cite

The preferences of women with ovarian cancer for oral versus intravenous recurrence regimens.

Journal Article Gynecol Oncol · August 2021 OBJECTIVE: To assess preferences of women with ovarian cancer regarding features of available anti-cancer regimens for platinum-resistant, biomarker-positive disease, with an emphasis on oral PARP inhibitor and standard intravenous (IV) chemotherapy regime ... Full text Link to item Cite

Medicaid Expansion Reduced Uninsured Surgical Hospitalizations And Associated Catastrophic Financial Burden.

Journal Article Health Aff (Millwood) · August 2021 An important function of health insurance is protecting enrollees from excessively burdensome charges for unanticipated medical events. Unexpected surgery can be financially catastrophic for uninsured people. By targeting the low-income uninsured populatio ... Full text Link to item Cite

Evaluation of the clinical Index of Stable febrile neutropenia risk stratification system for management of febrile neutropenia in gynecologic oncology patients.

Journal Article Gynecol Oncol Rep · August 2021 OBJECTIVE: Scoring systems have been developed to identify low risk patients with febrile neutropenia (FN) who may be candidates for outpatient management. We sought to validate the predictive accuracy of the Clinical Index of Stable Febrile Neutropenia (C ... Full text Link to item Cite

Evaluation of pelvic washing specimens in patients with endometrial cancer: Cytomorphological features, diagnostic agreement, and pathologist experience.

Journal Article Cancer Cytopathol · July 2021 BACKGROUND: Pelvic washings for patients with endometrial cancer is recommended but not used for staging. The International System for Reporting Serous Fluid Cytology (TIS) has standardized diagnostic categories, but the criteria remain incomplete. The 3 p ... Full text Link to item Cite

A quality improvement initiative to reduce venous thromboembolism on a gynecologic oncology service.

Journal Article Gynecol Oncol · July 2021 OBJECTIVE: To describe and evaluate the effects of implementation of a venous thromboembolism (VTE) prophylaxis quality improvement (QI) initiative on a gynecologic oncology service at a single institution. METHODS: Prior to 2018, no consensus gynecologic ... Full text Link to item Cite

Cost-effectiveness of prenatal screening methods for congenital heart defects in pregnancies conceived by in-vitro fertilization.

Journal Article Ultrasound Obstet Gynecol · June 2021 OBJECTIVES: To determine if a policy of universal fetal echocardiography (echo) in pregnancies conceived by in-vitro fertilization (IVF) is cost-effective as a screening strategy for congenital heart defects (CHDs) and to examine the cost-effectiveness of ... Full text Link to item Cite

Chemotherapy discontinuation processes in a gynecologic oncology population.

Journal Article Gynecol Oncol · May 2021 OBJECTIVE: We sought to categorize the processes by which gynecologic oncology patients stop chemotherapy and to evaluate associations between these processes and end-of-life outcome metrics. METHODS: A cohort of patients with metastatic or recurrent gynec ... Full text Link to item Cite

Universal Screening for Lynch Syndrome in Uterine Cancer Patients: A Quality Improvement Initiative

Journal Article Obstetrical and Gynecological Survey · April 1, 2021 Full text Cite

Association of Medicaid expansion with mortality from gynecologic cancers.

Journal Article Am J Obstet Gynecol · March 2021 Full text Link to item Cite

Universal screening for Lynch syndrome in uterine cancer patients: A quality improvement initiative.

Journal Article Gynecol Oncol · January 2021 OBJECTIVE: To determine the feasibility and effectiveness of a quality improvement initiative (QI) to adopt universal screening for Lynch syndrome in uterine cancer patients at an institution that previously employed age-based screening. METHODS: Prior to ... Full text Link to item Cite

Results and Clinical Utilization of Foundation Medicine Molecular Tumor Profiling in Uterine and Ovarian Cancers.

Journal Article Target Oncol · January 2021 BACKGROUND: Recent advances in next-generation sequencing have allowed for an increase in molecular tumor profiling. OBJECTIVE: We sought to assess the actionability and clinical utilization of molecular tumor profiling results obtained via Foundation Medi ... Full text Link to item Cite

Evidence-based medicine and clinical epidemiology

Chapter · January 1, 2021 As the body of scientific literature grows exponentially, the ability to interpret and apply the results of clinical research becomes increasingly important to the practice of medicine. This chapter presents the basics of epidemiologic study designs and th ... Full text Cite

The cost-effectiveness of ertapenem for the treatment of chorioamnionitis after cesarean delivery.

Journal Article J Matern Fetal Neonatal Med · December 2020 Background: Chorioamnionitis affects 1-4% of pregnancies, and patients who undergo cesarean delivery in the setting of chorioamnionitis have an increased risk of endometritis and surgical site infection (SSI). The standard treatment for chorioamnionitis af ... Full text Link to item Cite

Adherence to Oral Anticancer Therapeutics in the Gynecologic Oncology Population.

Journal Article Obstet Gynecol · December 2020 INTRODUCTION: To gain a better understanding of gynecologic oncology patient adherence to oral anticancer agents through both a cross-sectional survey of adherence and qualitative interviews with patients and clinicians regarding their experience with thes ... Full text Link to item Cite

Adjuvant treatment improves overall survival in women with high-intermediate risk early-stage endometrial cancer with lymphovascular space invasion.

Journal Article Int J Gynecol Cancer · November 2020 BACKGROUND: Adjuvant therapy in early-stage endometrial cancer has not shown a clear overall survival benefit, and hence, patient selection remains crucial. OBJECTIVE: To determine whether women with high-intermediate risk, early-stage endometrial cancer w ... Full text Link to item Cite

Cost-effectiveness analysis comparing "PARP inhibitors-for-all" to the biomarker-directed use of PARP inhibitor maintenance therapy for newly diagnosed advanced stage ovarian cancer.

Journal Article Gynecol Oncol · November 2020 OBJECTIVES: Clinical trials evaluating universal PARP inhibitor (PARPi) frontline maintenance therapy for advanced stage ovarian cancer have reported progression-free survival (PFS) benefit. It is unclear whether PARPi maintenance therapy will universally ... Full text Link to item Cite

Management of high, moderate, and low penetrance ovarian cancer susceptibility mutations: an assessment of current risk reduction practices.

Journal Article Int J Gynecol Cancer · October 2020 OBJECTIVE: Limited information exists regarding risk reduction strategies for women with moderate and low penetrance ovarian cancer susceptibility mutations. We sought to assess current risk reduction practice patterns for carriers of these mutations throu ... Full text Link to item Cite

Are Videos or Text Better for Describing Attributes in Stated-Preference Surveys?

Journal Article Patient · August 2020 OBJECTIVE: In stated-preference research, the conventional approach to describing study attributes is through text, often with easy-to-understand graphics. More recently, researchers have begun to present attribute descriptions and content in videos. Some ... Full text Link to item Cite

Randomized Phase II Trial of Carboplatin-Paclitaxel Compared with Carboplatin-Paclitaxel-Trastuzumab in Advanced (Stage III-IV) or Recurrent Uterine Serous Carcinomas that Overexpress Her2/Neu (NCT01367002): Updated Overall Survival Analysis.

Journal Article Clin Cancer Res · August 1, 2020 PURPOSE: Uterine-serous-carcinoma (USC) is an aggressive variant of endometrial cancer. On the basis of preliminary results of a multicenter, randomized phase II trial, trastuzumab (T), a humanized-mAb targeting Her2/Neu, in combination with carboplatin/pa ... Full text Link to item Cite

Incidence of venous thromboembolism among patients receiving neoadjuvant chemotherapy for advanced epithelial ovarian cancer.

Journal Article Int J Gynecol Cancer · April 2020 OBJECTIVES: Neoadjuvant chemotherapy may be considered for women with epithelial ovarian cancer who have poor performance status or a disease burden not amenable to primary cytoreductive surgery. Overlap exists between indications for neoadjuvant chemother ... Full text Link to item Cite

Society of gynecologic oncology future of physician payment reform task force: Lessons learned in developing and implementing surgical alternative payment models.

Journal Article Gynecol Oncol · March 2020 Full text Link to item Cite

Intraperitoneal chemotherapy following neoadjuvant chemotherapy and optimal interval tumor reductive surgery for advanced ovarian cancer.

Journal Article Gynecol Oncol · March 2020 OBJECTIVES: Intraperitoneal (IP) chemotherapy following neoadjuvant chemotherapy (NACT) and interval tumor reductive surgery (TRS) for advanced ovarian cancer is feasible, however, the impact on disease outcomes remains unclear. We compare outcomes of pati ... Full text Link to item Cite

Adjuvant therapy for early stage, endometrial cancer with lymphovascular space invasion: Is there a role for chemotherapy?

Journal Article Gynecol Oncol · March 2020 OBJECTIVES: Lymphovascular space invasion (LVSI) is an independent risk factor for recurrence and poor survival in early-stage endometrioid endometrial cancer (EEC), but optimal adjuvant treatment is unknown. We aimed to compare the survival of women with ... Full text Link to item Cite

Patient preferences for maintenance PARP inhibitor therapy in ovarian cancer treatment.

Journal Article Gynecol Oncol · March 2020 OBJECTIVE: To measure preferences of women with ovarian cancer regarding risks, side effects, costs and benefits afforded by maintenance therapy (MT) with a poly ADP ribose polymerase (PARP) inhibitor. METHODS: A discrete-choice experiment elicited prefere ... Full text Link to item Cite

Lidocaine-Prilocaine Cream Compared With Injected Lidocaine for Vulvar Biopsy: A Randomized Controlled Trial.

Journal Article Obstet Gynecol · February 2020 OBJECTIVE: To compare pain control during vulvar biopsy after either application of 5% lidocaine-prilocaine cream or injection of 1% lidocaine. METHODS: In a single-site randomized trial, patients who needed vulvar biopsy on a non-hair-bearing surface were ... Full text Link to item Cite

Off-study utilization of experimental therapies: Analysis of GOG249-eligible cohorts using real world data.

Journal Article Gynecol Oncol · January 2020 OBJECTIVE: Adjuvant management of women with high-intermediate- and high-risk early-stage endometrial cancer remains controversial. Recently published results of GOG 249 revealed that vaginal brachytherapy plus chemotherapy (VBT + CT) was not superior to w ... Full text Link to item Cite

Cell-free DNA for Down syndrome screening in obese women: Is it a cost-effective strategy?

Journal Article Prenat Diagn · January 2020 OBJECTIVE: Determine cost differences between cell-free DNA (cfDNA) and serum integrated screening (INT) in obese women given the limitations of aneuploidy screening in this population. METHODS: Using a decision-analytic model, we estimated the cost-effect ... Full text Link to item Cite

The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.

Journal Article J Alzheimers Dis · 2020 BACKGROUND: Perioperative neurocognitive disorders (PND) are common complications in older adults associated with increased 1-year mortality and long-term cognitive decline. One risk factor for worsened long-term postoperative cognitive trajectory is the A ... Full text Open Access Link to item Cite

Radiotherapy use in the treatment of gastrointestinal cancers in Medicare patients: An analysis of a CMS database

Conference JOURNAL OF CLINICAL ONCOLOGY · 2020 Cite

Patient preferences for attributes of primary surgical debulking versus neoadjuvant chemotherapy for treatment of newly diagnosed ovarian cancer.

Journal Article Cancer · December 15, 2019 BACKGROUND: Randomized trials have reported conflicting findings on survival for advanced-stage ovarian cancer treated with primary debulking surgery (PDS) versus neoadjuvant chemotherapy with interval debulking; surgical complications and mortality are hi ... Full text Link to item Cite

Simulated Costs of the ASCO Patient-Centered Oncology Payment Model in Medicare Beneficiaries With Newly Diagnosed Advanced Ovarian Cancer.

Journal Article J Oncol Pract · December 2019 PURPOSE: Efforts to curb the rising costs of cancer care while improving quality include alternative payment models (APMs), which offer incentives to reduce avoidable spending and provide high-quality and cost-efficient care. The impact of proposed APMs ha ... Full text Link to item Cite

Patient Preferences for Attributes of Primary Surgical Debulking Versus Neoadjuvant Chemotherapy for Treatment of Newly Diagnosed Ovarian Cancer

Journal Article Obstetrical and Gynecological Survey · December 1, 2019 Full text Cite

PCN532 WOMEN'S PREFERENCES ON BENEFITS, RISKS, AND SIDE EFFECTS OF MAINTENANCE PARP INHIBITOR THERAPY IN OVARIAN CANCER

Conference Value in Health · November 2019 Full text Cite

Place of death by region and urbanization among gynecologic cancer patients: 2006-2016.

Journal Article Gynecol Oncol · October 2019 OBJECTIVE: To evaluate associations between US region of residence and urbanization and the place of death among women with gynecologic malignancies in the United States. METHODS: A retrospective cross-sectional study was performed using publicly available ... Full text Link to item Cite

Gender variation in Medicare utilization and payments in gynecologic oncology.

Journal Article Gynecol Oncol · September 2019 OBJECTIVES: The Medicare Provider Utilization and Payment Data: Physician and Other Supplier Public Use File (POSPUF) and Medicare Physician and Other Supplier National Provider Identifier (POS NPI) Aggregate Report are publicly available files from the Ce ... Full text Link to item Cite

COST EFFECTIVENESS OF SELECTIVE COMPARED TO UNIVERSAL URINE SCREENING PROTOCOL PRIOR TO UROGYNECOLOGIC SURGERY

Conference INTERNATIONAL UROGYNECOLOGY JOURNAL · September 1, 2019 Link to item Cite

Constitutively active ESR1 mutations in gynecologic malignancies and clinical response to estrogen-receptor directed therapies.

Journal Article Gynecol Oncol · July 2019 OBJECTIVE: Endocrine therapy is often considered as a treatment for hormone-responsive gynecologic malignancies. In breast cancer, activating mutations in the estrogen receptor (mutESR1) contribute to therapeutic resistance to endocrine therapy, especially ... Full text Link to item Cite

Phase II trial of nintedanib in patients with bevacizumab-resistant recurrent epithelial ovarian, tubal, and peritoneal cancer.

Journal Article Gynecol Oncol · June 2019 BACKGROUND: Bevacizumab provides benefit in epithelial ovarian cancer (EOC), yet resistance to bevacizumab often occurs. We determined if nintedanib, a tyrosine kinase inhibitor of VEGF, FGF, and PDGF receptors has antitumor activity in bevacizumab-resista ... Full text Link to item Cite

Reduction in opioid use and postoperative pain scores after elective laparotomy with implementation of enhanced recovery after surgery protocol on a gynecologic oncology service.

Journal Article Int J Gynecol Cancer · June 2019 OBJECTIVE: Enhanced Recovery After Surgery (ERAS) protocols are designed to mitigate the physiologic stress response created by surgery, to decrease the time to resumption of daily activities, and to improve overall recovery. This study aims to investigate ... Full text Link to item Cite

Therapy discontinuation processes in a gynecologic oncology population

Conference JOURNAL OF CLINICAL ONCOLOGY · May 20, 2019 Link to item Cite

Patient preferences for maintenance PARP therapy in ovarian cancer treatment.

Conference Journal of Clinical Oncology · May 20, 2019 5558 Background: Maintenance therapy with PARP inhibitors has become prevalent in treating ovarian cancer. However, the preferences of women with ovarian cancer regarding the risks, side effects and benefits afforded by maintenan ... Full text Cite

Management of high, moderate, and low penetrance ovarian cancer susceptibility gene mutations: An assessment of current practice patterns.

Conference Journal of Clinical Oncology · May 20, 2019 1536 Background: Limited information exists regarding appropriate risk-reduction strategies for women with moderate and low penetrance ovarian cancer (OVCA) susceptibility mutations. We sought to assess current practice patterns ... Full text Cite

Associations between lymphovascular space invasion, nodal recurrence, and survival in patients with surgical stage I endometrioid endometrial adenocarcinoma.

Journal Article World J Surg Oncol · May 10, 2019 OBJECTIVE: To investigate the predictive value of lymphovascular space invasion (LVSI) for nodal recurrence and overall survival (OS) in patients with stage I endometrioid endometrial cancer (EC) following surgical staging that included adequate lymph node ... Full text Link to item Cite

Cost-effectiveness of hyperthermic intraperitoneal chemotherapy (HIPEC) at interval debulking of epithelial ovarian cancer following neoadjuvant chemotherapy.

Journal Article Gynecol Oncol · May 2019 OBJECTIVES: A recent randomized controlled trial demonstrated an overall survival benefit to the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to neoadjuvant chemotherapy (NACT) for stage III epithelial ovarian cancer (EOC). The objective o ... Full text Link to item Cite

Impact of a documentation intervention on health-assessment metrics on an inpatient gynecologic oncology service.

Journal Article Gynecol Oncol · May 2019 OBJECTIVE: Accurate documentation is critical for patient care and hospital reimbursement. We sought to improve the accuracy of severity of illness (SOI) and risk of mortality (ROM) scores through implementation of documentation initiatives. METHODS: We pe ... Full text Link to item Cite

A pilot study of lower extremity lymphedema, lower extremity function, and quality of life in women after minimally invasive endometrial cancer staging surgery.

Journal Article Gynecol Oncol · May 2019 OBJECTIVE: The primary aim of this study was to pilot the use of an objective measurement technique to prospectively evaluate the incidence of lower extremity lymphedema (LEL) after minimally invasive staging surgery for endometrial cancer. Secondary objec ... Full text Link to item Cite

Radiation Records in the National Cancer Database: Variations in Coding and/or Practice Can Significantly Alter Survival Results.

Journal Article JCO Clin Cancer Inform · May 2019 PURPOSE: The aim of the current work was to quantify internally inconsistent and anomalous radiation therapy (RT) data in the National Cancer Database (NCDB) and determine their association with overall survival (OS) using node-positive uterine cancer as a ... Full text Link to item Cite

PNS232 ARE VIDEOS OR TEXT BETTER FOR DESCRIBING ATTRIBUTES IN STATED-PREFERENCE SURVEYS? SOME EXPERTS WILL BE SURPRISED

Conference Value in Health · May 2019 Full text Cite

The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.

Journal Article J Am Geriatr Soc · April 2019 BACKGROUND/OBJECTIVES: Every year, up to 40% of the more than 16 million older Americans who undergo anesthesia/surgery develop postoperative cognitive dysfunction (POCD) or delirium. Each of these distinct syndromes is associated with decreased quality of ... Full text Open Access Link to item Cite

U.S. Food and Drug Administration-Approved Poly (ADP-Ribose) Polymerase Inhibitor Maintenance Therapy for Recurrent Ovarian Cancer: A Cost-Effectiveness Analysis.

Journal Article Obstet Gynecol · April 2019 OBJECTIVE: We sought to determine whether use of a poly (ADP-ribose) polymerase inhibitor is cost effective for maintenance treatment of platinum-sensitive recurrent ovarian cancer. METHODS: A decision analysis model compared four maintenance strategies: 1 ... Full text Link to item Cite

Impact of a Documentation Intervention on Health-Assessment Metrics on an Inpatient Gynecologic Oncology Service [24A]: Correction.

Journal Article Obstet Gynecol · April 2019 Full text Link to item Cite

Induction of Labor versus Scheduled Cesarean in Morbidly Obese Women: A Cost-Effectiveness Analysis.

Journal Article Am J Perinatol · March 2019 OBJECTIVE: To assess the costs, complication rates, and harm-benefit tradeoffs of induction of labor (IOL) compared to scheduled cesarean delivery (CD) in women with class III obesity. STUDY DESIGN: We conducted a cost analysis of IOL versus scheduled CD i ... Full text Link to item Cite

Targeted composite value-based endpoints in platinum-sensitive recurrent ovarian cancer.

Journal Article Gynecol Oncol · March 2019 OBJECTIVES: FDA-approved treatments for platinum-sensitive recurrent ovarian cancer (PSROC) include bevacizumab and PARP inhibitors (PARPi); clinical decisions regarding therapy must be made prior to initiating chemotherapy. Using the American Society of C ... Full text Link to item Cite

Health Services Research: Not just retrospective chart reviews.

Journal Article Gynecol Oncol · March 2019 Full text Link to item Cite

Changes in insurance coverage for cancer patients receiving brachytherapy before and after enactment of the Affordable Care Act.

Journal Article Brachytherapy · 2019 PURPOSE: The Patient Protection and Affordable Care Act called for expansion of Medicaid in 2014. As some states elected to expand Medicaid and others did not, the goal of this study was to determine the effect of Medicaid expansion on the insurance status ... Full text Link to item Cite

Preferences of women with epithelial ovarian cancer for aspects of genetic testing.

Journal Article Gynecol Oncol Res Pract · 2019 BACKGROUND: Although genetic testing is recommended for women with epithelial ovarian cancer (EOC), little is known about patient preferences for various testing options. We measured relative preferences for attributes of testing in women with EOC referred ... Full text Link to item Cite

Hysterectomy with sentinel lymph node biopsy in the setting of pre-operative diagnosis of endometrial intraepithelial neoplasia: A cost-effectiveness analysis.

Journal Article Gynecol Oncol · December 2018 OBJECTIVES: Sentinel lymph node biopsy (SLNB) may be considered in the setting of a pre-operative diagnosis of endometrial intraepithelial neoplasia (EIN) due to high rates of concurrent invasive cancer. The aim of this study is to compare the cost-effecti ... Full text Link to item Cite

Gender trends in gynecologic oncology authorship: Implications for the critical evaluation of gender distribution in academic rank and leadership positions.

Journal Article Gynecol Oncol · December 2018 OBJECTIVE: To investigate trends in the representation of women as first, last, or co-authors in Gynecologic Oncology (GO) publications over the past 15 years. To compare rates of female authorship in GO versus general Obstetrics and Gynecology (Ob/Gyn) an ... Full text Link to item Cite

The cost-effectiveness of ertapenem for the treatment of chorioamnionitis after cesarean section

Conference American Journal of Obstetrics and Gynecology · December 2018 Full text Cite

PMD180 - THE VALUE TO WOMEN WITH OVARIAN CANCER OF GENE VARIANTS WITH KNOWN AND UNKNOWN SIGNIFICANCE: A DISCRETE CHOICE EXPERIMENT

Conference Value in Health · October 2018 Full text Cite

Randomized Phase II Trial of Carboplatin-Paclitaxel Versus Carboplatin-Paclitaxel-Trastuzumab in Uterine Serous Carcinomas That Overexpress Human Epidermal Growth Factor Receptor 2/neu.

Journal Article J Clin Oncol · July 10, 2018 Purpose Uterine serous carcinoma is a rare, aggressive variant of endometrial cancer. Trastuzumab is a humanized monoclonal antibody that targets human epidermal growth factor receptor 2 (HER2)/neu, a receptor overexpressed in 30% of uterine serous carcino ... Full text Link to item Cite

Measuring the Health Benefits of the Affordable Care Act for Young Women.

Journal Article Obstet Gynecol · June 2018 Full text Link to item Cite

Assessment of activating estrogen receptor 1 (ESR1) mutations in gynecologic malignancies.

Conference Journal of Clinical Oncology · May 20, 2018 Full text Cite

Variability in Medicare utilization and payment among gynecologic oncologists.

Conference Journal of Clinical Oncology · May 20, 2018 Full text Cite

Prospective Evaluation of Lymph Node Processing at Staging Surgery for High-grade Endometrial Cancer.

Journal Article Int J Gynecol Pathol · May 2018 To determine whether the processing of additional adipose tissue collected during lymph node (LN) dissection results in the identification of additional LNs during endometrial cancer (EC) staging and to determine if the division of LNs into nodal basin-spe ... Full text Link to item Cite

Health Care Disparities in Cancer Patients Receiving Radiation: Changes in Insurance Status After Medicaid Expansion Under the Affordable Care Act.

Conference Int J Radiat Oncol Biol Phys · May 1, 2018 PURPOSE: To compare insurance status in cancer patients receiving radiation before and after Medicaid expansion under the Patient Protection and Affordable Care Act (ACA), in both expanded and non-expanded states. METHODS AND MATERIALS: Newly diagnosed can ... Full text Link to item Cite

Estimating potential for savings for low risk endometrial cancer using the Endometrial Cancer Alternative Payment Model (ECAP): A companion paper to the Society of Gynecologic Oncology Report on the Endometrial Cancer Alternative Payment Model.

Journal Article Gynecol Oncol · May 2018 OBJECTIVE: To design an endometrial cancer (EC) alternative payment (ECAP) model focused on surgical management of EC, as well as identify drivers of cost in order to develop opportunities for cost-savings while maintaining quality of care. METHODS: Nation ... Full text Link to item Cite

Society of Gynecologic Oncology Future of Physician Payment Reform Task Force report: The Endometrial Cancer Alternative Payment Model (ECAP).

Journal Article Gynecol Oncol · May 2018 Health care in the United States is in the midst of a significant transformation from a "fee for service" to a "fee for value" based model. The Medicare Access and CHIP Reauthorization Act of 2015 has only accelerated this transition. Anticipating these re ... Full text Link to item Cite

Estimating the number of potential family members eligible for BRCA1 and BRCA2 mutation testing in a "Traceback" approach.

Journal Article Genet Epidemiol · February 2018 U.S. guidelines recommend BRCA1/2 mutation testing for women diagnosed with high-grade ovarian cancer (HGOC) to increase recognition of carriers, but most remain unidentified and at risk. Accordingly, an approach termed "Traceback" has been proposed in whi ... Full text Link to item Cite

Estimating Cost-effectiveness of a Multimodal Ovarian Cancer Screening Program in the United States: Secondary Analysis of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS).

Journal Article JAMA Oncol · February 1, 2018 IMPORTANCE: The United Kingdom Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) is the largest randomized clinical trial to evaluate screening's impact on ovarian cancer mortality, assigning women to multimodal screening (MMS) with serum cancer an ... Full text Link to item Cite

Predicting 6- and 12-Month Risk of Mortality in Patients With Platinum-Resistant Advanced-Stage Ovarian Cancer: Prognostic Model to Guide Palliative Care Referrals.

Journal Article Int J Gynecol Cancer · February 2018 OBJECTIVE: Predictive models are increasingly being used in clinical practice. The aim of the study was to develop a predictive model to identify patients with platinum-resistant ovarian cancer with a prognosis of less than 6 to 12 months who may benefit f ... Full text Link to item Cite

Trends in Insurance Status Among Patients Diagnosed With Cancer Before and After Implementation of the Affordable Care Act.

Journal Article J Oncol Pract · February 2018 PURPOSE: The Affordable Care Act (ACA) aimed to increase insurance coverage through key provisions such as expansion of Medicaid eligibility and enforcement of an individual mandate. The objective of this study is to examine the impact of the ACA on insura ... Full text Link to item Cite

Geriatric Assessment: Precision Medicine for Older Adults With Cancer

Journal Article Journal of Oncology Practice · February 2018 Full text Cite

The use of patient-reported outcome tools in Gynecologic Oncology research, clinical practice, and value-based care.

Journal Article Gynecol Oncol · January 2018 Patient-reported outcomes (PRO) are defined as a report of a patient's symptoms, function and general well-being that comes directly from the patient, without interpretation of the response by a medical provider. As greater emphasis is placed on high-quali ... Full text Link to item Cite

Is it reasonable to administer pegfilgrastim on day 1 of a myelosuppressive chemotherapy regimen? A cost-utility analysis.

Journal Article Cancer Treat Res Commun · 2018 BACKGROUND: There is recent evidence supporting the safety and efficacy of same-day dosing of pegfilgrastim in patients undergoing chemotherapy. OBJECTIVE: To determine the cost-effectiveness of pegfilgrastim on day 1 (D1) versus day 2 (D2) for primary pre ... Full text Link to item Cite

High-volume providers and brachytherapy practice: A Medicare provider utilization and payment analysis.

Journal Article Brachytherapy · 2018 PURPOSE: Brachytherapy is an important component of the treatment of gynecologic and prostate cancers, with data supporting its impact on clinical outcomes. Prior data have suggested that brachytherapy tends to be focused at high-volume centers. Medicare r ... Full text Link to item Cite

Maintenance Poly (ADP-ribose) Polymerase Inhibitor Therapy for Ovarian Cancer: Precision Oncology or One Size Fits All?

Journal Article J Clin Oncol · December 20, 2017 Full text Link to item Cite

ASCO Value Framework Highlights the Relative Value of Treatment Options in Ovarian Cancer.

Journal Article J Oncol Pract · December 2017 PURPOSE: The ASCO value framework allows physicians and patients to compare the relative value of novel treatments. Our aim was to assess the value of three frontline ovarian cancer therapies by using this framework. METHODS: From phase III, randomized con ... Full text Link to item Cite

Use of a novel sentinel lymph node mapping algorithm reduces the need for pelvic lymphadenectomy in low-grade endometrial cancer.

Journal Article Gynecol Oncol · December 2017 OBJECTIVES: To evaluate the capability of a novel sentinel lymph node (SLN) mapping algorithm to reduce the need for pelvic lymphadenectomy (PLND) in patients with low-grade (G1-2) endometrial cancer (LGEC). METHODS: Patients with LGEC underwent evaluation ... Full text Link to item Cite

Data-Derived Treatment Duration Goal for Cervical Cancer: Should 8 Weeks Remain the Target in the Era of Concurrent Chemoradiation?

Journal Article JCO Clin Cancer Inform · November 2017 PURPOSE: Prior studies have demonstrated the importance of treatment duration (TD) in radiation therapy (RT) for cervical cancer, with an 8-week goal based primarily on RT alone. This study uses a contemporary cohort to estimate the time point by which com ... Full text Link to item Cite

Race-specific molecular alterations correlate with differential outcomes for black and white endometrioid endometrial cancer patients.

Journal Article Cancer · October 15, 2017 BACKGROUND: The objective of this study was to identify molecular alterations associated with disease outcomes for white and black patients with endometrioid endometrial cancer (EEC). METHODS: EEC samples from black (n = 17) and white patients (n = 13) wer ... Full text Link to item Cite

Cost Effectiveness of Risk-Reducing Mastectomy versus Surveillance in BRCA Mutation Carriers with a History of Ovarian Cancer.

Journal Article Ann Surg Oncol · October 2017 BACKGROUND: The appropriate management of breast cancer risk in BRCA mutation carriers following ovarian cancer diagnosis remains unclear. We sought to determine the survival benefit and cost effectiveness of risk-reducing mastectomy (RRM) among women with ... Full text Link to item Cite

Quality of life is significantly associated with survival in women with advanced epithelial ovarian cancer: An ancillary data analysis of the NRG Oncology/Gynecologic Oncology Group (GOG-0218) study.

Journal Article Gynecol Oncol · October 2017 OBJECTIVE: Evaluate association between baseline quality of life (QOL) and changes in QOL measured by FACT-O TOI with progression-free disease (PFS) and overall survival (OS) in advanced epithelial ovarian cancer (EOC). METHODS: Patients enrolled in GOG-02 ... Full text Link to item Cite

Insurance coverage among women diagnosed with a gynecologic malignancy before and after implementation of the Affordable Care Act.

Journal Article Gynecol Oncol · September 2017 OBJECTIVE: The Patient Protection and Affordable Care Act (ACA) included provisions to expand insurance coverage by expanding Medicaid eligibility, providing subsidies of private coverage and enforcing an individual mandate. The objective of this study is ... Full text Link to item Cite

The costs of adding laparoscopy to the management of advanced stage epithelial ovarian cancer.

Journal Article Gynecol Oncol · September 2017 Full text Link to item Cite

Cost-effectiveness of opportunistic salpingectomy for ovarian cancer prevention.

Journal Article Gynecol Oncol · August 2017 OBJECTIVES: Data suggesting a link between the fallopian tube and ovarian cancer have led to an increase in rates of salpingectomy at the time of pelvic surgery, a practice known as opportunistic salpingectomy (OS). However, the potential benefits, risks a ... Full text Link to item Cite

Rationale and study protocol for the Patient-Centered Outcome Aid (PCOA) randomized controlled trial: A personalized decision tool for newly diagnosed ovarian cancer patients.

Journal Article Contemp Clin Trials · June 2017 Full text Link to item Cite

Mortality reduction and cost-effectiveness of performing hysterectomy at the time of risk-reducing salpingo-oophorectomy for prophylaxis against serous/serous-like uterine cancers in BRCA1 mutation carriers.

Journal Article Gynecol Oncol · June 2017 OBJECTIVE: To estimate the survival benefit and cost-effectiveness of performing hysterectomy during risk-reducing salpingo-oophorectomy (RRSO) for BRCA1 mutation carriers. METHODS: Based on a recent prospective cohort study indicating an elevated incidenc ... Full text Link to item Cite

Shared decision-making in ovarian cancer.

Conference Journal of Clinical Oncology · May 20, 2017 5549 Background: The value of shared decision-making in ovarian cancer is relatively unexplored. The goal of this study was to test a new decision aid, Patient Centered Outcome Aid (PCOA), that facilitates shared decision-making ... Full text Cite

Management of platinum-sensitive recurrent ovarian cancer (PSROC) in the era of biologics: Can ASCO’s net health benefits (NHB) inform our decisions?

Conference Journal of Clinical Oncology · May 20, 2017 5544 Background: The ASCO value framework allows assessment of novel cancer therapies based on NHB. We assessed novel biologic therapies in the management of PSROC. Methods: ASCO’s revised value framework NHBs were constructed fo ... Full text Cite

Cost-effectiveness of ovarian cancer screening: An analysis of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) from a U.S. health system perspective.

Conference Journal of Clinical Oncology · May 20, 2017 6608 Background: UKCTOCS is the largest randomized controlled trial to evaluate screening’s impact on ovarian cancer mortality, assigning women to multimodal screening (MMS) with serum CA125 interpreted with a risk algorithm; ann ... Full text Cite

Evaluating the repertoire of immune checkpoint markers expressed on peripheral and ascites CD8⁺ T cells in ovarian cancer.

Conference Journal of Clinical Oncology · May 20, 2017 5571 Background: Understanding the immune checkpoint marker repertoire can facilitate development of therapeutic strategies to improve efficacy of immune-based therapies. We used a novel high-dimensional flow cytometry panel to d ... Full text Cite

Primary Versus Preoperative Radiation for Locally Advanced Vulvar Cancer.

Journal Article Int J Gynecol Cancer · May 2017 OBJECTIVES: The objective of this study was to evaluate patterns of care and the survival impact of primary radiation and preoperative radiation therapy with surgery in women with locally advanced vulvar cancer using a large national cohort. METHODS AND MA ... Full text Link to item Cite

Impact of Chemotherapy and Radiotherapy on Management of Early Stage Clear Cell and Papillary Serous Carcinoma of the Uterus.

Journal Article Int J Gynecol Cancer · May 2017 OBJECTIVE: The aim of the study was to assess interaction of lymph node dissection (LND), adjuvant chemotherapy (CT), and radiotherapy (RT) in stage I uterine papillary serous carcinoma (UPSC) and uterine clear cell carcinoma (UCC). METHODS/MATERIALS: The ... Full text Link to item Cite

Is There a Role for Ovarian Cancer Screening in High-Risk Women?

Journal Article J Clin Oncol · May 1, 2017 Full text Link to item Cite

The "value" of value in gynecologic oncology practice in the United States: Society of Gynecologic Oncology evidence-based review and recommendations.

Journal Article Gynecol Oncol · April 2017 Full text Link to item Cite

Prior breast cancer and tamoxifen exposure does not influence outcomes in women with uterine papillary serous carcinoma.

Journal Article Gynecol Oncol · March 2017 OBJECTIVES: To evaluate progression-free survival (PFS) and overall survival (OS) outcomes in women diagnosed with uterine papillary serous carcinoma (UPSC) who have had (UPSCBR+) or have not had (UPSCBR-) an antecedent history of breast cancer and to corr ... Full text Link to item Cite

Cost Comparison of Genetic Testing Strategies in Women With Epithelial Ovarian Cancer.

Journal Article J Oncol Pract · February 2017 PURPOSE: The advent of multigene panels has increased genetic testing options for women with epithelial ovarian cancer (EOC). We designed a decision model to compare costs and probabilities of identifying a deleterious mutation or variant of uncertain sign ... Full text Link to item Cite

Are different methotrexate regimens as first line therapy for low risk gestational trophoblastic neoplasia more cost effective than the dactinomycin regimen used in GOG 0174?

Journal Article Gynecol Oncol · January 2017 OBJECTIVES: Gynecologic Oncology Group (GOG) 0174 compared weekly intramuscular methotrexate (MTX) with biweekly pulsed intravenous dactinomycin (Act-D) as single-agent chemotherapy for low-risk gestational trophoblastic neoplasia (GTN). Act-D had a higher ... Full text Link to item Cite

Disparities in the surgical staging of high-grade endometrial cancer in the United States.

Journal Article Gynecol Oncol Res Pract · 2017 BACKGROUND: The National Comprehensive Cancer Network (NCCN) and the Society of Gynecologic Oncology (SGO) recommend lymph node sampling (LNS) as a key component in the surgical staging of high-grade endometrial cancer. Our goal was to examine surgical sta ... Full text Open Access Link to item Cite

Promoting Same-Day Discharge for Gynecologic Oncology Patients in Minimally Invasive Hysterectomy.

Journal Article J Minim Invasive Gynecol · 2017 STUDY OBJECTIVE: Despite clear data demonstrating feasibility, safety, and cost-effectiveness of same-day discharge after minimally invasive hysterectomy, a paucity of data suggests ways to increase same-day discharge rates. Our objectives were to promote ... Full text Link to item Cite

Multidisciplinary approach to manage antenatally suspected placenta percreta: updated algorithm and patient outcomes.

Journal Article Gynecol Oncol Res Pract · 2017 BACKGROUND: Due to the significant morbidity and mortality associated with placenta percreta, alternative management options are needed. Beginning in 2005, our institution implemented a multidisciplinary strategy to patients with suspected placenta percret ... Full text Open Access Link to item Cite

Definitive Chemoradiotherapy for Vulvar Cancer.

Journal Article Int J Gynecol Cancer · November 2016 OBJECTIVES: This study aimed to evaluate clinical outcomes after chemoradiation (CRT) for the definitive (nonsurgical) treatment of vulvar cancer. MATERIALS AND METHODS: Women with vulvar cancer treated with definitive CRT at a single academic institution ... Full text Link to item Cite

Levonorgestrel Intrauterine Device as an Endometrial Cancer Prevention Strategy in Obese Women: A Cost-Effectiveness Analysis.

Journal Article Obstet Gynecol · October 2016 OBJECTIVE: To estimate the cost-effectiveness of the levonorgestrel intrauterine device (IUD) as an endometrial cancer prevention strategy in obese women. METHODS: A modified Markov model was used to compare IUD placement at age 50 with usual care among wo ... Full text Link to item Cite

Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.

Journal Article J Natl Compr Canc Netw · September 2016 This selection from the NCCN Guidelines for Ovarian Cancer focuses on the less common ovarian histopathologies (LCOHs), because new algorithms were added for LCOHs and current algorithms were revised for the 2016 update. The new LCOHs algorithms include cl ... Full text Link to item Cite

Tumor grade and chemotherapy response in endometrioid endometrial cancer.

Journal Article Gynecol Oncol Rep · August 2016 The objective of this study is to evaluate the association between tumor grade and response to chemotherapy in patients with endometrioid endometrial adenocarcinoma. Patients with advanced or recurrent endometrioid endometrial adenocarcinoma of known tumor ... Full text Link to item Cite

Performance of sentinel lymph node biopsy in high-risk endometrial cancer.

Journal Article Gynecol Oncol Rep · August 2016 OBJECTIVE: To determine the rate and performance of sentinel lymph node (SLN) mapping among women with high-risk endometrial cancers. METHODS: Patients diagnosed between 2012 and 2015 with uterine cancer of grade 3 endometrioid, clear cell, serous or carci ... Full text Link to item Cite

A personalized paradigm in the treatment of platinum-resistant ovarian cancer - A cost utility analysis of genomic-based versus cytotoxic therapy.

Journal Article Gynecol Oncol · July 2016 OBJECTIVE: To assess the cost-effectiveness of a strategy employing genomic-based tumor testing to guide therapy for platinum-resistant ovarian cancer. METHODS: A decision model was created to compare standard of care (SOC) cytotoxic chemotherapy to a geno ... Full text Link to item Cite

Does Routine Posttreatment PET/CT Add Value to the Care of Women With Locally Advanced Cervical Cancer?

Journal Article Int J Gynecol Cancer · June 2016 OBJECTIVES: The aim of this study was to determine the necessary reduction in recurrence rate that would make postchemoradiation positron emission tomography (PET)/computed tomography (CT) to direct completion hysterectomy for locally advanced cervical can ... Full text Link to item Cite

Is Intraperitoneal Chemotherapy Dead?

Journal Article Obstet Gynecol · June 2016 Full text Link to item Cite

Chemotherapy and radiotherapy in early stage uterine papillary serous and clear-cell carcinoma: A National Cancer Data Base study.

Conference Journal of Clinical Oncology · May 20, 2016 Full text Cite

Patient preference-weighted assessments using the ASCO value framework in recurrent, platinum-sensitive ovarian cancer.

Conference Journal of Clinical Oncology · May 20, 2016 Full text Cite

Phase II evaluation of nintedanib in the treatment of bevacizumab-resistant persistent/recurrent ovarian, fallopian tube, or primary peritoneal carcinoma.

Conference Journal of Clinical Oncology · May 20, 2016 Full text Cite

Sensitivity of ovarian cancer cells to acetaminophen reveals biological pathways that affect patient survival.

Journal Article Mol Clin Oncol · March 2016 Experimental and epidemiological data support the potential activity of acetaminophen against ovarian cancer (OVCA). In this study, we sought to confirm the activity of acetaminophen in OVCA cell lines and to investigate the molecular basis of response. A ... Full text Link to item Cite

Prospective Evaluation of Lymph Node Processing at Staging Surgery for High-Grade Endometrial Cancer

Conference MODERN PATHOLOGY · February 1, 2016 Link to item Cite

Body mass index and mortality in endometrial cancer: A systematic review and meta-analysis.

Journal Article Gynecol Oncol · January 2016 OBJECTIVE: To evaluate the association between body mass index (BMI) and mortality in women with endometrial cancer. METHODS: A systematic review was performed utilizing a Medline search with Mesh keywords 'endometrial neoplasms' and ('body mass index' or ... Full text Link to item Cite

Impact of postoperative nausea and vomiting prophylaxis with dexamethasone on the risk of recurrence of endometrial cancer.

Journal Article Curr Med Res Opin · 2016 OBJECTIVE: To assess whether antiemetic doses of dexamethasone are associated with an increased risk of cancer recurrence in women who underwent surgery for endometrial cancer. RESEARCH DESIGN AND METHODS: This is a retrospective study at an academic unive ... Full text Link to item Cite

Analysis of in vitro chemoresponse assays in endometrioid endometrial adenocarcinoma: an observational ancillary analysis.

Journal Article Gynecol Oncol Res Pract · 2016 BACKGROUND: Chemotherapy plays a role in the treatment of endometrioid endometrial cancer (EEC); however, tumor grade may affect response. Our objective was to evaluate associations between tumor grade and in vitro chemoresponse. METHODS: We conducted an a ... Full text Open Access Link to item Cite

Cognitive function during and six months following chemotherapy for front-line treatment of ovarian, primary peritoneal or fallopian tube cancer: An NRG oncology/gynecologic oncology group study.

Journal Article Gynecol Oncol · December 2015 OBJECTIVES: Changes in cognitive function have been identified in and reported by many cancer survivors. These changes have the potential to impact patient quality of life and functional ability. This prospective longitudinal study was designed to quantify ... Full text Link to item Cite

A multi-institutional study of outcomes in stage I-III uterine carcinosarcoma.

Journal Article Gynecol Oncol · November 2015 OBJECTIVE: To evaluate the use of adjuvant therapy after primary surgery for stage I-III uterine carcinosarcoma (CS). METHODS: A multi-institutional retrospective study of women with stage I-III CS was conducted. Analyses were stratified by stage (I/II and ... Full text Link to item Cite

Benefits and Harms of Breast Cancer Screening: A Systematic Review.

Journal Article JAMA · October 20, 2015 IMPORTANCE: Patients need to consider both benefits and harms of breast cancer screening. OBJECTIVE: To systematically synthesize available evidence on the association of mammographic screening and clinical breast examination (CBE) at different ages and in ... Full text Link to item Cite

Improving NCCN guideline-adherent care for ovarian cancer: Value of an intervention.

Journal Article Gynecol Oncol · September 2015 OBJECTIVE: To estimate the potential cost-effectiveness of an intervention to improve adherence to National Comprehensive Cancer Network (NCCN) guideline-based care for ovarian cancer. METHODS: A modified Markov model with a 5-year time horizon estimated t ... Full text Link to item Cite

Consensus in controversy: The modified Delphi method applied to Gynecologic Oncology practice.

Journal Article Gynecol Oncol · September 2015 OBJECTIVES: To determine the degree of consensus regarding the probabilities of outcomes associated with IP/IV and IV chemotherapy. METHODS: A survey was administered to an expert panel using the Delphi method. Ten ovarian cancer experts were asked to esti ... Full text Link to item Cite

Bariatric surgery as a means to decrease mortality in women with type I endometrial cancer - An intriguing option in a population at risk for dying of complications of metabolic syndrome.

Journal Article Gynecol Oncol · September 2015 OBJECTIVE: To estimate the cost-effectiveness and utility of a strategy of offering weight loss surgery (WLS) to women with low risk stage I endometrial cancer (EC) and BMI≥40kg/m(2). METHODS: A modified Markov state transition model was designed to compar ... Full text Link to item Cite

Lumbee Native American ancestry and the incidence of aggressive histologic subtypes of endometrial cancer.

Journal Article Gynecol Oncol Rep · August 2015 OBJECTIVE: The Lumbee Indian tribe is the largest Native American tribe in North Carolina, with about 55,000 enrolled members who mostly reside in southeastern counties. We evaluated whether Lumbee heritage is associated with high-risk histologic subtypes ... Full text Link to item Cite

Patient and physician factors associated with participation in cervical and uterine cancer trials: an NRG/GOG247 study.

Journal Article Gynecol Oncol · July 2015 PURPOSE: The aim of this study was to identify patient and physician factors related to enrollment onto Gynecologic Oncology Group (GOG) trials. METHODS: Prospective study of women with primary or recurrent cancer of the uterus or cervix treated at a GOG i ... Full text Link to item Cite

Selective cardiac surveillance in patients with gynecologic cancer undergoing treatment with pegylated liposomal doxorubicin (PLD).

Journal Article Gynecol Oncol · June 2015 OBJECTIVE: The study objective was to examine the safety and cost savings of selective cardiac surveillance (CS) during treatment with pegylated liposomal doxorubicin (PLD). METHODS: A retrospective, dual institution study of women receiving PLD for the tr ... Full text Link to item Cite

Patient-reported outcomes as end points and outcome indicators in solid tumours.

Journal Article Nat Rev Clin Oncol · June 2015 Patient-reported outcome (PRO) measures, such as quality of life, have been associated with relevant clinical end points and are prognostic for survival outcomes in a variety of solid cancers in adults. In the past few years, PROs have garnered a greater i ... Full text Link to item Cite

Abstract 10: Does routine post-treatment PET/CT add value to the care of women with locally advanced cervical cancer?

Journal Article Gynecologic Oncology · June 2015 Full text Cite