Scholars@Duke
Sua Yoo

Sua Yoo

Associate Professor of Radiation Oncology
Radiation Oncology
sua.yoo@duke.edu
Box 3295 Med Ctr, Durham, NC
Duke South Physics, Durham, NC
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Selected Publications

Breast Cancer

Chapter · 2022 Cite

Dosimetric variation in preoperative partial breast radiosurgery assessed by deformable image registrations.

Journal Article J Radiosurg SBRT · 2022 OBJECTIVE: To assess dosimetric variation caused by breast deformation in breast radiosurgery based on deformable image registration. METHODS: This study included 30 patients who were treated in the prone position for preoperative partial breast radiosurge ... Link to item Cite

Clinical Experience With Machine Learning-Based Automated Treatment Planning for Whole Breast Radiation Therapy.

Journal Article Adv Radiat Oncol · 2021 PURPOSE: The machine learning-based automated treatment planning (MLAP) tool has been developed and evaluated for breast radiation therapy planning at our institution. We implemented MLAP for patient treatment and assessed our clinical experience for its p ... Full text Open Access Link to item Cite

Abstract P4-12-10: Clinical implementation of the machine learning-based automated treatment planning tool for whole breast radiotherapy

Conference Cancer Research · February 15, 2020 AbstractObjectives: The machine learning (ML)-based automated treatment planning tool has been developed and evaluated for whole breast radiotherapy. This study implemented the tool in clinic and compared pl ... Full text Cite

Accuracy and efficiency of image-guided radiation therapy (IGRT) for preoperative partial breast radiosurgery.

Journal Article J Radiosurg SBRT · 2020 OBJECTIVE: To analyze and evaluate accuracy and efficiency of IGRT process for preoperative partial breast radiosurgery. METHODS: Patients were initially setup with skin marks and 5 steps were performed: (1) Initial orthogonal 2D kV images, (2) pre-treatme ... Open Access Link to item Cite

Single dose partial breast irradiation using an MRI linear accelerator in the supine and prone treatment position.

Journal Article Clin Transl Radiat Oncol · January 2019 BACKGROUND: In selected patients with early-stage and low-risk breast cancer, an MRI-linac based treatment might enable a radiosurgical, non-invasive alternative for current standard breast conserving therapy. AIM: To investigate whether single dose accele ... Full text Link to item Cite

Goal-Driven Beam Setting Optimization for Whole-Breast Radiation Therapy.

Journal Article Technol Cancer Res Treat · January 1, 2019 PURPOSE: To develop an automated optimization program to generate optimal beam settings for whole-breast radiation therapy driven by clinically oriented goals. MATERIALS AND METHODS: Forty patients were retrospectively included in this study. Each patient' ... Full text Open Access Link to item Cite

Automatic Planning of Whole Breast Radiation Therapy Using Machine Learning Models.

Journal Article Front Oncol · 2019 Purpose: To develop an automatic treatment planning system for whole breast radiation therapy (WBRT) based on two intensity-modulated tangential fields, enabling near-real-time planning. Methods and Materials: A total of 40 WBRT plans from a single institu ... Full text Open Access Link to item Cite

Treatment constraints for single dose external beam preoperative partial breast irradiation in early-stage breast cancer.

Journal Article Clin Transl Radiat Oncol · October 2017 BACKGROUND: Following breast-conserving surgery and post-operative 3D-conformal accelerated partial breast irradiation (APBI), suboptimal cosmetic results have been reported. Preoperative radiation delivery to the intact tumor enables better target visuali ... Full text Link to item Cite

WE-AB-209-05: Development of an Ultra-Fast High Quality Whole Breast Radiotherapy Treatment Planning System.

Journal Article Med Phys · June 2016 PURPOSE: To enable near-real-time (<20sec) and interactive planning without compromising quality for whole breast RT treatment planning using tangential fields. METHODS: Whole breast RT plans from 20 patients treated with single energy (SE, 6MV, 10 patient ... Full text Link to item Cite

Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers.

Journal Article Int J Radiat Oncol Biol Phys · July 15, 2015 PURPOSE: Women with biologically favorable early-stage breast cancer are increasingly treated with accelerated partial breast radiation (PBI). However, treatment-related morbidities have been linked to the large postoperative treatment volumes required for ... Full text Link to item Cite

Dosimetric comparison of preoperative single-fraction partial breast radiotherapy techniques: 3D CRT, noncoplanar IMRT, coplanar IMRT, and VMAT.

Journal Article J Appl Clin Med Phys · January 8, 2015 The purpose of this study was to compare dosimetric parameters of treatment plans among four techniques for preoperative single-fraction partial breast radiotherapy in order to select an optimal treatment technique. The techniques evaluated were noncoplana ... Full text Link to item Cite

Dosimetric comparison of preoperative single-fraction partial breast radiotherapy techniques: 3D CRT, noncoplanar IMRT, coplanar IMRT, and VMAT

Journal Article Journal of Applied Clinical Medical Physics · January 1, 2015 The purpose of this study was to compare dosimetric parameters of treatment plans among four techniques for preoperative single-fraction partial breast radiotherapy in order to select an optimal treatment technique. The techniques evaluated were noncoplana ... Cite

A phase 1 trial of preoperative partial breast radiation therapy: Patient selection, target delineation, and dose delivery.

Journal Article Pract Radiat Oncol · 2015 PURPOSE: Diffusion of accelerated partial breast irradiation into clinical practice is limited by the need for specialized equipment and training. The accessible external beam technique yields unacceptable complication rates, likely from large postoperativ ... Full text Link to item Cite

Dosimetric comparison of 3D conformal, IMRT, and V-MAT techniques for accelerated partial-breast irradiation (APBI).

Journal Article Med Dosim · 2014 The purpose is to dosimetrically compare the following 3 delivery techniques: 3-dimensional conformal radiation therapy (3D-CRT), intensity-modulated arc therapy (IMRT), and volumetric-modulated arc therapy (V-MAT) in the treatment of accelerated partial-b ... Full text Link to item Cite

SU-D-500-06: On-Board Robotic Multi-Pinhole SPECT System for Prone Breast Imaging.

Journal Article Med Phys · June 2013 PURPOSE: To investigate a novel Single Photon Emission Computed Tomography (SPECT) system for on-board molecular and functional imaging in partial breast radiation therapy of prone patients. METHODS: Computer-simulation studies were performed for on-board ... Full text Link to item Cite

Investigation of sliced body volume (SBV) as respiratory surrogate.

Journal Article J Appl Clin Med Phys · January 7, 2013 The purpose of this study was to evaluate the sliced body volume (SBV) as a respiratory surrogate by comparing with the real-time position management (RPM) in phantom and patient cases. Using the SBV surrogate, breathing signals were extracted from unsorte ... Full text Open Access Link to item Cite

SU‐E‐CAMPUS‐J‐04: Evaluating Radiation‐Induced Changes with Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI in Patients with Early Stage Breast Cancer Treated with Stereotactic Body Radiotherapy: Initial Results

Conference Medical Physics · January 1, 2013 Purpose: Pre‐operative stereotactic body radiosurgery (SBRT) was delivered in a single fraction to treat patients with early stage breast cancer; however, few data are available regarding radiation‐induced changes by SBRT. In this work, diffusion weighted ... Full text Cite

Breast Cancer

Chapter · 2022 Cite

Dosimetric variation in preoperative partial breast radiosurgery assessed by deformable image registrations.

Journal Article J Radiosurg SBRT · 2022 OBJECTIVE: To assess dosimetric variation caused by breast deformation in breast radiosurgery based on deformable image registration. METHODS: This study included 30 patients who were treated in the prone position for preoperative partial breast radiosurge ... Link to item Cite

Clinical Experience With Machine Learning-Based Automated Treatment Planning for Whole Breast Radiation Therapy.

Journal Article Adv Radiat Oncol · 2021 PURPOSE: The machine learning-based automated treatment planning (MLAP) tool has been developed and evaluated for breast radiation therapy planning at our institution. We implemented MLAP for patient treatment and assessed our clinical experience for its p ... Full text Open Access Link to item Cite

Abstract P4-12-10: Clinical implementation of the machine learning-based automated treatment planning tool for whole breast radiotherapy

Conference Cancer Research · February 15, 2020 AbstractObjectives: The machine learning (ML)-based automated treatment planning tool has been developed and evaluated for whole breast radiotherapy. This study implemented the tool in clinic and compared pl ... Full text Cite

Accuracy and efficiency of image-guided radiation therapy (IGRT) for preoperative partial breast radiosurgery.

Journal Article J Radiosurg SBRT · 2020 OBJECTIVE: To analyze and evaluate accuracy and efficiency of IGRT process for preoperative partial breast radiosurgery. METHODS: Patients were initially setup with skin marks and 5 steps were performed: (1) Initial orthogonal 2D kV images, (2) pre-treatme ... Open Access Link to item Cite

Single dose partial breast irradiation using an MRI linear accelerator in the supine and prone treatment position.

Journal Article Clin Transl Radiat Oncol · January 2019 BACKGROUND: In selected patients with early-stage and low-risk breast cancer, an MRI-linac based treatment might enable a radiosurgical, non-invasive alternative for current standard breast conserving therapy. AIM: To investigate whether single dose accele ... Full text Link to item Cite

Goal-Driven Beam Setting Optimization for Whole-Breast Radiation Therapy.

Journal Article Technol Cancer Res Treat · January 1, 2019 PURPOSE: To develop an automated optimization program to generate optimal beam settings for whole-breast radiation therapy driven by clinically oriented goals. MATERIALS AND METHODS: Forty patients were retrospectively included in this study. Each patient' ... Full text Open Access Link to item Cite

Automatic Planning of Whole Breast Radiation Therapy Using Machine Learning Models.

Journal Article Front Oncol · 2019 Purpose: To develop an automatic treatment planning system for whole breast radiation therapy (WBRT) based on two intensity-modulated tangential fields, enabling near-real-time planning. Methods and Materials: A total of 40 WBRT plans from a single institu ... Full text Open Access Link to item Cite

Treatment constraints for single dose external beam preoperative partial breast irradiation in early-stage breast cancer.

Journal Article Clin Transl Radiat Oncol · October 2017 BACKGROUND: Following breast-conserving surgery and post-operative 3D-conformal accelerated partial breast irradiation (APBI), suboptimal cosmetic results have been reported. Preoperative radiation delivery to the intact tumor enables better target visuali ... Full text Link to item Cite

WE-AB-209-05: Development of an Ultra-Fast High Quality Whole Breast Radiotherapy Treatment Planning System.

Journal Article Med Phys · June 2016 PURPOSE: To enable near-real-time (<20sec) and interactive planning without compromising quality for whole breast RT treatment planning using tangential fields. METHODS: Whole breast RT plans from 20 patients treated with single energy (SE, 6MV, 10 patient ... Full text Link to item Cite

Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers.

Journal Article Int J Radiat Oncol Biol Phys · July 15, 2015 PURPOSE: Women with biologically favorable early-stage breast cancer are increasingly treated with accelerated partial breast radiation (PBI). However, treatment-related morbidities have been linked to the large postoperative treatment volumes required for ... Full text Link to item Cite

Dosimetric comparison of preoperative single-fraction partial breast radiotherapy techniques: 3D CRT, noncoplanar IMRT, coplanar IMRT, and VMAT.

Journal Article J Appl Clin Med Phys · January 8, 2015 The purpose of this study was to compare dosimetric parameters of treatment plans among four techniques for preoperative single-fraction partial breast radiotherapy in order to select an optimal treatment technique. The techniques evaluated were noncoplana ... Full text Link to item Cite

Dosimetric comparison of preoperative single-fraction partial breast radiotherapy techniques: 3D CRT, noncoplanar IMRT, coplanar IMRT, and VMAT

Journal Article Journal of Applied Clinical Medical Physics · January 1, 2015 The purpose of this study was to compare dosimetric parameters of treatment plans among four techniques for preoperative single-fraction partial breast radiotherapy in order to select an optimal treatment technique. The techniques evaluated were noncoplana ... Cite

A phase 1 trial of preoperative partial breast radiation therapy: Patient selection, target delineation, and dose delivery.

Journal Article Pract Radiat Oncol · 2015 PURPOSE: Diffusion of accelerated partial breast irradiation into clinical practice is limited by the need for specialized equipment and training. The accessible external beam technique yields unacceptable complication rates, likely from large postoperativ ... Full text Link to item Cite

Dosimetric comparison of 3D conformal, IMRT, and V-MAT techniques for accelerated partial-breast irradiation (APBI).

Journal Article Med Dosim · 2014 The purpose is to dosimetrically compare the following 3 delivery techniques: 3-dimensional conformal radiation therapy (3D-CRT), intensity-modulated arc therapy (IMRT), and volumetric-modulated arc therapy (V-MAT) in the treatment of accelerated partial-b ... Full text Link to item Cite

SU-D-500-06: On-Board Robotic Multi-Pinhole SPECT System for Prone Breast Imaging.

Journal Article Med Phys · June 2013 PURPOSE: To investigate a novel Single Photon Emission Computed Tomography (SPECT) system for on-board molecular and functional imaging in partial breast radiation therapy of prone patients. METHODS: Computer-simulation studies were performed for on-board ... Full text Link to item Cite

Investigation of sliced body volume (SBV) as respiratory surrogate.

Journal Article J Appl Clin Med Phys · January 7, 2013 The purpose of this study was to evaluate the sliced body volume (SBV) as a respiratory surrogate by comparing with the real-time position management (RPM) in phantom and patient cases. Using the SBV surrogate, breathing signals were extracted from unsorte ... Full text Open Access Link to item Cite

SU‐E‐CAMPUS‐J‐04: Evaluating Radiation‐Induced Changes with Diffusion Weighted MRI and Dynamic Contrast Enhanced MRI in Patients with Early Stage Breast Cancer Treated with Stereotactic Body Radiotherapy: Initial Results

Conference Medical Physics · January 1, 2013 Purpose: Pre‐operative stereotactic body radiosurgery (SBRT) was delivered in a single fraction to treat patients with early stage breast cancer; however, few data are available regarding radiation‐induced changes by SBRT. In this work, diffusion weighted ... Full text Cite

Investigation of sliced body volume (SBV) as respiratory surrogate

Journal Article Journal of Applied Clinical Medical Physics · January 1, 2013 The purpose of this study was to evaluate the sliced body volume (SBV) as a respiratory surrogate by comparing with the real-time position management (RPM) in phantom and patient cases. Using the SBV surrogate, breathing signals were extracted from unsorte ... Full text Cite

Implementing and integrating a clinically driven electronic medical record for radiation oncology in a large medical enterprise.

Journal Article Front Oncol · 2013 PURPOSE/OBJECTIVE: While our department is heavily invested in computer-based treatment planning, we historically relied on paper-based charts for management of Radiation Oncology patients. In early 2009, we initiated the process of conversion to an electr ... Full text Link to item Cite

Imaging system QA of a medical accelerator, Novalis Tx, for IGRT per TG 142: our 1 year experience.

Journal Article J Appl Clin Med Phys · July 5, 2012 American Association of Physicists in Medicine (AAPM) task group (TG) 142 has recently published a report to update recommendations of the AAPM TG 40 report and add new recommendations concerning medical accelerators in the era of image-guided radiation th ... Full text Open Access Link to item Cite

SU-E-T-559: Evaluation of Flatening Filter Free (FFF) Beams in Radiotherapy of Head and Neck Cancer.

Journal Article Med Phys · June 2012 PURPOSE: To investigate th applicability of the flattening filter free (FFF) to fractionated radiotherapy of head and neck cancer. METHODS: Twelve patients previously treated with IMRT were selected. A SIB protocol was chosen so that 66/54 Gy were prescrib ... Full text Link to item Cite

Comparison of 3D conformal breast radiation treatment plans using the anisotropic analytical algorithm and pencil beam convolution algorithm.

Journal Article Radiother Oncol · May 2012 Featured Publication PURPOSE: To investigate (1) dosimetric differences between plans calculated using the anisotropic analytical algorithm (AAA) and pencil beam convolution (PBC) algorithm, (2) the plan quality achieved using AAA compared to PBC based on dosimetric parameters ... Full text Link to item Cite

Effect of increasing experience on dosimetric and clinical outcomes in the management of malignant pleural mesothelioma with intensity-modulated radiation therapy.

Journal Article Int J Radiat Oncol Biol Phys · May 1, 2012 PURPOSE: To assess the impact of increasing experience with intensity-modulated radiation therapy (IMRT) after extrapleural pneumonectomy (EPP) for malignant pleural mesothelioma (MPM). METHODS AND MATERIALS: The records of all patients who received IMRT f ... Full text Link to item Cite

Quality assurance for image-guided radiation therapy utilizing CT-based technologies: a report of the AAPM TG-179.

Journal Article Med Phys · April 2012 Featured Publication PURPOSE: Commercial CT-based image-guided radiotherapy (IGRT) systems allow widespread management of geometric variations in patient setup and internal organ motion. This document provides consensus recommendations for quality assurance protocols that ensu ... Full text Link to item Cite

On-Board Digital Tomosynthesis: An Emerging New Technology for Image-Guided Radiation Therapy

Chapter · January 1, 2012 External-beam radiation therapy is a common treatment modality for cancers. e treatment course typically consists of 30-40 daily fractions of 180-200 cGy over several weeks. On-board imaging (OBI) guidance is oen designed to track shis in patient positioni ... Full text Cite

Preoperative single fraction partial breast radiotherapy for early-stage breast cancer.

Journal Article Int J Radiat Oncol Biol Phys · January 1, 2012 Featured Publication PURPOSE: Several recent series evaluating external beam accelerated partial breast irradiation (PBI) have reported adverse cosmetic outcomes, possibly related to large volumes of normal tissue receiving near-prescription doses. We hypothesized that deliver ... Full text Link to item Cite

Imaging system QA of a medical accelerator, Novalis Tx, for IGRT per TG 142: Our 1 year experience

Journal Article Journal of Applied Clinical Medical Physics · January 1, 2012 Featured Publication American Association of Physicists in Medicine (AAPM) task group (TG) 142 has recently published a report to update recommendations of the AAPM TG 40 report and add new recommendations concerning medical accelerators in the era of image-guided radiation th ... Full text Cite

TU‐E‐BRC‐08: Investigation of Anatomical Surrogate for 4DCT Imaging

Conference Medical Physics · January 1, 2011 Purpose: Respiratory signal for 4DCT is typically extracted using an external respiratory positioning management device (RPM) which is often inconvenient and time consuming. The efficiency of 4DCT imaging could be substantially improved if anatomical body ... Full text Cite

A comparison of clinical and dosimetric outcomes in patients receiving partial breast irradiation with photon-only versus mixed photon/electron treatment plans.

Journal Article Med Dosim · 2011 Several series evaluating external-beam partial breast irradiation (PBI) have linked negative cosmetic outcomes to large normal tissue treatment volumes. We compared patients treated with PBI whose treatment plans included only photons to those whose plans ... Full text Link to item Cite

Intensity-modulated radiation therapy for anal malignancies: a preliminary toxicity and disease outcomes analysis.

Journal Article Int J Radiat Oncol Biol Phys · December 1, 2010 PURPOSE: Intensity-modulated radiation therapy (IMRT) has the potential to reduce toxicities associated with chemoradiotherapy in the treatment of anal cancer. This study reports the results of using IMRT in the treatment of anal cancer. METHODS AND MATERI ... Full text Link to item Cite

Impact of volumetric modulated arc therapy technique on treatment with partial breast irradiation.

Journal Article Int J Radiat Oncol Biol Phys · September 1, 2010 Featured Publication PURPOSE: To investigate the technical feasibility of volumetric modulated arc therapy (V-MAT) in the delivery of partial breast irradiation (PBI). METHODS AND MATERIALS: V-MAT and the standard, three-dimensional conformal radiotherapy (3D-CRT), were compar ... Full text Link to item Cite

Kilovoltage cone-beam CT: comparative dose and image quality evaluations in partial and full-angle scan protocols.

Journal Article Med Phys · July 2010 PURPOSE: To assess imaging dose of partial and full-angle kilovoltage CBCT scan protocols and to evaluate image quality for each protocol. METHODS: The authors obtained the CT dose index (CTDI) of the kilovoltage CBCT protocols in an on-board imager by ion ... Full text Link to item Cite

Estimation of computed tomography dose index in cone beam computed tomography: MOSFET measurements and Monte Carlo simulations.

Journal Article Health Phys · May 2010 To address the lack of accurate dose estimation method in cone beam computed tomography (CBCT), we performed point dose metal oxide semiconductor field-effect transistor (MOSFET) measurements and Monte Carlo (MC) simulations. A Varian On-Board Imager (OBI) ... Full text Link to item Cite

Investigation into the feasibility of using PRESAGE/optical-CT dosimetry for the verification of gating treatments.

Journal Article Phys Med Biol · April 21, 2010 This work presents an investigation into the use of PRESAGE dosimeters with an optical-CT scanner as a 3D dosimetry system for quantitative verification of respiratory-gated treatments. The CIRS dynamic thorax phantom was modified to incorporate a moving P ... Full text Link to item Cite

Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes.

Journal Article Int J Radiat Oncol Biol Phys · March 1, 2010 Featured Publication PURPOSE: Dosimetric results and treatment delivery efficiency of RapidArc plans to those of conventional intensity-modulated radiotherapy (IMRT) plans were compared using the Eclipse treatment planning system for high-risk prostate cancer. MATERIALS AND ME ... Full text Link to item Cite

SU‐GG‐T‐136: Treatment Plans Comparison with Static‐Gantry IMRT and RapidArcTM for Head‐And‐Neck Cancers Involving Cervical Lymph Nodes

Conference Medical Physics · January 1, 2010 Purpose: To compare the dosimetric results and treatment efficiency of intensity modulated arc therapy using RapidArc™ to static‐gantry IMRT plans for conventional fractionation treatment of head‐and‐neck cancer. Materials and Methods: This study evaluated ... Full text Cite

SU‐GG‐T‐225: Gantry‐Angle Dependence of a 2D Ion Chamber Array for IMAT QA

Conference Medical Physics · January 1, 2010 Purpose: Gantry‐angle dependence of dose measurement for intensity‐modulated arc therapy (IMAT) quality assurance (QA) using a two‐dimensional ion chamber array may be significant. A new device, the gantry angle sensor, has been provided to compensate for ... Full text Cite

SU‐GG‐T‐583: Dosimetric Comparison of Anisotropic Analytical and Pencil Beam Convolution Algorithms in Breast Cancer Radiation Treatment Planning

Conference Medical Physics · January 1, 2010 Purpose: The anisotropic analytical algorithm (AAA) has been shown to provide more accurate dose calculation due to 3D scatter and inhomogeneity corrections than the pencil beam convolution algorithm (PBC) for inhomogeneous anatomical regions such as lung ... Full text Cite

SU‐GG‐I‐57: Dose and Image Quality Evaluation for Partial and Full‐Angle Kilovoltage Cone‐Beam CT Protocols

Conference Medical Physics · January 1, 2010 Purpose: To assess imaging dose of partial and full‐angle CBCT scan protocols, and to evaluate their image quality. Method and Materials: The CTDI of the six new CBCT protocols for Varian OBI were obtained by ion chamber (IC) measurements and Monte Carlo ( ... Full text Cite

TH‐B‐BRA‐01: Treatment Planning Based on CBCT Images Acquired for On‐Line Position Verification

Conference Medical Physics · January 1, 2010 The primary purpose of in‐room CBCT volumetric 3D verification images is to verify patient position and target localization in real‐time. However they are also used for clinical treatment evaluation or plan modification for adaptive radiation therapy. Dail ... Full text Cite

Volumetric arc intensity-modulated therapy for spine body radiotherapy: comparison with static intensity-modulated treatment.

Journal Article Int J Radiat Oncol Biol Phys · December 1, 2009 PURPOSE: This clinical study evaluates the feasibility of using volumetric arc-modulated treatment (VMAT) for spine stereotactic body radiotherapy (SBRT) to achieve highly conformal dose distributions that spare adjacent organs at risk (OAR) with reduced t ... Full text Link to item Cite

Intensity-modulated radiation therapy for anal cancer.

Journal Article Oncology (Williston Park) · November 15, 2009 The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin. This therapy results in long-term disease-free survival and sphincter preservation in the majority of patients. Tempering these posi ... Link to item Cite

Intensity-modulated radiation therapy for anal cancer

Journal Article ONCOLOGY · November 15, 2009 The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin. This therapy results in long-term disease-free survival and sphincter preservation in the majority of patients. Tempering these posi ... Cite

Tradeoffs of integrating real-time tracking into IGRT for prostate cancer treatment.

Journal Article Phys Med Biol · September 7, 2009 This study investigated the integration of the Calypso real-time tracking system, based on implanted ferromagnetic transponders and a detector array, into the current process for image-guided radiation treatment (IGRT) of prostate cancer at our institution ... Full text Link to item Cite

Comparison of online IGRT techniques for prostate IMRT treatment: adaptive vs repositioning correction.

Journal Article Med Phys · May 2009 This study compares three online image guidance techniques (IGRT) for prostate IMRT treatment: bony-anatomy matching, soft-tissue matching, and online replanning. Six prostate IMRT patients were studied. Five daily CBCT scans from the first week were acqui ... Full text Link to item Cite

Refinement of treatment setup and target localization accuracy using three-dimensional cone-beam computed tomography for stereotactic body radiotherapy.

Journal Article Int J Radiat Oncol Biol Phys · February 1, 2009 PURPOSES: To quantitatively compare two-dimensional (2D) orthogonal kV with three-dimensional (3D) cone-beam CT (CBCT) for target localization; and to assess intrafraction motion with kV images in patients undergoing stereotactic body radiotherapy (SBRT). ... Full text Link to item Cite

SU‐FF‐T‐309: Quality Assurance for Imaging Guided Stereotactic RadioSurgery with Novalis Tx™ System

Conference Medical Physics · January 1, 2009 Purpose: To present QA measurements over extended periods at our institute and recommend a QA program for image‐guided radiosurgery on Novalis Tx system. Method and Materials: Novalis Tx system is developed based on a Trilogy linear accelerator featuring B ... Full text Cite

SU‐FF‐T‐130: Radiotherapy Treatment Plans with RapidArc for Head‐And‐Neck Cancer

Conference Medical Physics · January 1, 2009 Purpose: The purpose of this study is to compare RapidArc plans and conventional IMRT plans for head‐and‐neck cancer treatment involving bilateral nodes. Methods and Materials: This study included 10 locally advanced head‐and‐neck cancer patients. The plan ... Full text Cite

SU‐FF‐T‐301: Clinical Implementation and Commission of Volumetric Modulated Arc Therapy

Conference Medical Physics · January 1, 2009 Purpose Volumetric modulated arc therapy (VMAT) is a rotational IMRT modality that combines dose rate modulation with gantry and MLC motion, thereby increasing the complexity of IMRT delivery. Effective implementation of this technology is still quite new ... Full text Cite

SU‐FF‐J‐56: Integrating Real‐Time Tracking Into Image Guided Radiation Therapy for Prostate Cancer Treatment

Conference Medical Physics · January 1, 2009 Purpose: To investigate how a real‐time tracking technique, based on implanted transponders, could be effectively integrated into the current process for image‐guided radiation treatment of prostate cancer. Method and Materials: Current prostate IGRT proce ... Full text Cite

TH‐A‐211A‐01: Digital Tomosynthesis for Target Localization

Conference Medical Physics · January 1, 2009 Any deviation between treated and planned volumes for 3‐D conformal therapy, such as IMRT, may cause an adverse clinical outcome. It is therefore critical to minimize all potential deviations using an on‐board (or real‐time) imaging procedure immediately p ... Full text Cite

SU‐FF‐T‐567: Volumetric Modulated Arc Therapy for Spine Body Radiotherapy: Comparison with Static Intensity Modulated Treatment

Conference Medical Physics · January 1, 2009 Purpose: Volumetric modulated arc treatment (VMAT) reduces treatment time over static beam intensity modulated treatment (IMRT) by delivering IMRT using arcs. This clinical study evaluates the feasibility of using VMAT for spine stereotactic body radiother ... Full text Cite

SU‐FF‐T‐574: Radiotherapy Treatment Plans with RapidArc for Prostate Cancer Involving Seminal Vesicles

Conference Medical Physics · January 1, 2009 Purpose: The purpose of this report is to compare RapidArc plans and conventional IMRT plans for prostate cancer involving seminal vesicles. Methods and Materials: This study included 10 patients. The planning‐target volume (PTV) contained the prostate and ... Full text Cite

SU‐FF‐J‐12: HU and Dosimetric Comparison of Six Cone‐Beam CT Acquisition Techniques for Radiation Therapy Planning

Conference Medical Physics · January 1, 2009 Purpose: It has been shown that cone‐beam computed tomography (CBCT) can be used in dose calculation for treatment planning. This study investigates the HU and dosimetric properties of six CBCT techniques in comparison with conventional CT to determine whi ... Full text Cite

Clinical evaluation of positioning verification using digital tomosynthesis and bony anatomy and soft tissues for prostate image-guided radiotherapy.

Journal Article Int J Radiat Oncol Biol Phys · January 1, 2009 Featured Publication PURPOSE: To evaluate on-board digital tomosynthesis (DTS) for patient positioning vs. two-dimensional (2D) radiography and three-dimensional cone beam (CBCT). METHODS AND MATERIALS: A total of 92 image sessions from 9 prostate cancer patients were analyzed ... Full text Link to item Cite

Analysis of image quality for real-time target tracking using simultaneous kV-MV imaging.

Journal Article Med Phys · December 2008 Real-time tracking can provide high accuracy localization for a moving target and minimize the effect of motion. Simultaneous kV-MV imaging has been proposed as a real-time tracking technique by utilizing the existing kV on-board imager (OBI) and the MV el ... Full text Link to item Cite

Moving from IMRT QA measurements toward independent computer calculations using control charts.

Journal Article Radiother Oncol · December 2008 BACKGROUND AND PURPOSE: In this study, we investigated IMRT QA using Statistical Process Control for the purpose of comparing the processes of patient-specific measurements and the corresponding independent computer calculations. MATERIALS AND METHODS: Poi ... Full text Link to item Cite

Process control analysis of IMRT QA: implications for clinical trials.

Journal Article Phys Med Biol · September 21, 2008 The purpose of this study is two-fold: first is to investigate the process of IMRT QA using control charts and second is to compare control chart limits to limits calculated using the standard deviation (sigma). Head and neck and prostate IMRT QA cases fro ... Full text Link to item Cite

Intensity-modulated radiotherapy for resected mesothelioma: the Duke experience.

Journal Article Int J Radiat Oncol Biol Phys · July 15, 2008 PURPOSE: To assess the safety and efficacy of intensity-modulated radiotherapy (IMRT) after extrapleural pneumonectomy for malignant pleural mesothelioma. METHODS AND MATERIALS: Thirteen patients underwent IMRT after extrapleural pneumonectomy between July ... Full text Link to item Cite

Integration of cone-beam CT in stereotactic body radiation therapy.

Journal Article Technol Cancer Res Treat · April 2008 This report describes the technique and initial experience using cone beam CT (CBCT) for localization of treatment targets in patients undergoing stereotactic body radiation therapy (SBRT). Patients selected for SBRT underwent 3-D or 4-D CT scans in a cust ... Full text Link to item Cite

Assessment of the residual error in soft tissue setup in patients undergoing partial breast irradiation: results of a prospective study using cone-beam computed tomography.

Journal Article Int J Radiat Oncol Biol Phys · March 15, 2008 Featured Publication PURPOSE: On-board cone-beam computed tomography (CBCT) provides soft tissue information that may improve setup accuracy in patients undergoing accelerated partial breast irradiation (APBI). We used CBCT to assess the residual error in soft tissue after two ... Full text Link to item Cite

On-line re-optimization of prostate IMRT plans for adaptive radiation therapy.

Journal Article Phys Med Biol · February 7, 2008 For intermediate and high risk prostate cancer, both the prostate gland and seminal vesicles are included in the clinical target volume. Internal motion patterns of these two organs vary, presenting a challenge for adaptive treatment. Adaptive techniques s ... Full text Link to item Cite

SU‐GG‐J‐177: The Application of An ASi‐Based EPID to Guide Intensity Modulated Radiation Therapy (IMRT) of Head‐And‐Neck Cancer

Conference Medical Physics · January 1, 2008 Purpose: In head‐and‐neck IMRT treatment, doses to targets and critical organs are affected by many factors including patient positioning, weight loss and tumor shrinkage. To ensure therapeutic effectiveness, re‐planning with a new CT is often conducted. H ... Full text Cite

SU‐GG‐J‐81: Efficacy of Patient Setup Correction Procedure in Prostate Radiotherapy

Conference Medical Physics · January 1, 2008 Purpose: Using an on‐board cone‐beam CT (CBCT) based statistical margin model to determine whether a prostate center‐of‐mass (COM) based translation correction procedure can significantly reduce the CTV‐to‐PTV margin required for prostate patients who were ... Full text Cite

SU‐GG‐I‐52: Conversion of On‐Board Digital TomoSynthesis (DTS) to HU Values

Conference Medical Physics · January 1, 2008 Purpose: To investigate a method to convert the pixel values of DTS images to HU values with reference HU values from CT images. Method and Materials: This study included CT and DTS images of two phantoms (Catphan and a chest phantom) and three patients (p ... Full text Cite

SU‐GG‐J‐119: Localization Accuracy of Target Verification System Using Digitial Tomosynthesis (DTS)

Conference Medical Physics · January 1, 2008 Purposes: A research platform was developed for target verification using digital tomosynthesis (DTS). To verify its accuracy, a phantom study was conducted and several clinical cases were investigated. Method and Materials: customer‐developed reconstructi ... Full text Cite

TU‐FF‐A2‐06: The Verification of Respiratory‐Gated Radiation Treatments Using 3D Dosimetry Techniques

Conference Medical Physics · January 1, 2008 Purpose: This work investigates the feasibility of verifying respiratory gated treatments using a new 3D dosimetry system consisting of a radiochromic plastic (PRESAGE™) with optical‐CT readout. Method and Materials: Three identical PRESAGE™ dosimeters (5c ... Full text Cite

SU‐GG‐T‐53: Integrating An Online Adaptive IMRT Process to the Prostate IGRT

Conference Medical Physics · January 1, 2008 Purpose: To investigate the feasibility of a novel online IMRT re‐optimization process. This online process can be an integral part to the current prostate IGRT paradigm to augment the existing patient alignment techniques for cases with complex daily orga ... Full text Cite

SU‐GG‐J‐47: Clinical Implementation of An Integrated System for Image‐Guided Radiation Therapy (IGRT) and Adaptive Radiation Therapy (ART)

Conference Medical Physics · January 1, 2008 Purpose: It is critical that image‐guided radiation therapy (IGRT) and adaptive radiation therapy (ART) are performed with clearly defined goals without abusing the technologies. This study illustrates the current integrated system that provides efficient ... Full text Cite

SU‐GG‐T‐255: Experimental Verification of Lung Tumor Dose with Radiochromic Film

Conference Medical Physics · January 1, 2008 Purpose: To assess the absorbed doses in and around lung tumor by performing radiochromic film measurements. Method and Materials: A phantom was made to have a water equivalent central core, a low‐density middle layer and a water equivalent outer layer to ... Full text Cite

Comparison of radiation doses between cone beam CT and multi detector CT: TLD measurements.

Journal Article Radiat Prot Dosimetry · 2008 In recent years, wide beam computed tomography (CT) technique has become standard in radiation oncology whereas there is little information about radiation dose assessments for the technique. A point dose measurement method was employed to assess the radia ... Full text Link to item Cite

On-board patient positioning for head-and-neck IMRT: comparing digital tomosynthesis to kilovoltage radiography and cone-beam computed tomography.

Journal Article Int J Radiat Oncol Biol Phys · October 1, 2007 PURPOSE: High-precision intensity-modulated radiotherapy demands high patient positioning accuracy. On-board digital tomosynthesis (DTS) provides three-dimensional (3D) image guidance for daily positioning with a lower imaging dose, faster acquisition, and ... Full text Link to item Cite

Evaluation of three types of reference image data for external beam radiotherapy target localization using digital tomosynthesis (DTS).

Journal Article Med Phys · August 2007 Digital tomosynthesis (DTS) is a fast, low-dose three-dimensional (3D) imaging approach which yields slice images with excellent in-plane resolution, though low plane-to-plane resolution. A stack of DTS slices can be reconstructed from a single limited-ang ... Full text Link to item Cite

A model for optimizing adenoviral delivery in human cancer gene therapy trials.

Journal Article Hum Gene Ther · June 2007 Optimization of adenoviral delivery to the target volume is required for adenovirus-mediated cancer gene therapy to reach its maximal potential. The purpose of these studies was to develop a model of gene expression to improve adenovirus-mediated cancer ge ... Full text Link to item Cite

A greedy heuristic using adjoint functions for the optimization of seed and needle configurations in prostate seed implant.

Journal Article Phys Med Biol · February 7, 2007 We continue our work on the development of an efficient treatment-planning algorithm for prostate seed implants by incorporation of an automated seed and needle configuration routine. The treatment-planning algorithm is based on region of interest (ROI) ad ... Full text Link to item Cite

Multi-species prostate implant treatment plans incorporating 192Ir and 125I using a Greedy Heuristic based 3D optimization algorithm.

Journal Article Med Phys · February 2007 The goals of interstitial implant brachytherapy include delivery of the target dose in a uniform manner while sparing sensitive structures, and minimizing the number of needles and sources. We investigated the use of a multi-species source arrangement (192 ... Full text Link to item Cite

MO‐SAMS‐AUD‐01: Daily Localization — I: Kilovolt Imaging

Journal Article Medical Physics · January 1, 2007 As high‐precision 3‐D conformal radiation therapy and intensity‐modulated radiation therapy have become standard practice, radiographic imaging using kilovoltage (kV) x‐ray sources has been rapidly implemented for in‐room target localization and patient po ... Full text Cite

TU‐EE‐A2‐05: Challenges in Limiting Kidney Dose When Delivering Total Body Irradiation (TBI) for Patients with Severe Systemic Sclerosis (SSc)

Conference Medical Physics · January 1, 2007 Purpose: To describe challenges in limiting kidney dose when delivering TBI to SSc patients enrolled on a multicenter Phase II/III SCOT (Scleroderma Cyclophosphamide or Transplantation) protocol. Material and Methods: The SCOT protocol uses a preparative r ... Full text Cite

SU‐FF‐J‐58: Clinical Evaluation Using Digital Tomosynthesis for Positioning Verification of Breath‐Hold Liver Treatment

Conference Medical Physics · January 1, 2007 Purpose: To demonstrate clinical feasibility of generating digital tomosynthesis (DTS) in a single breath‐hold (BH) period compared to multiple BH periods for CBCT acquisition and to examine on‐board BH‐DTS as an efficient alternative to BH‐CBCT for target ... Full text Cite

SU‐FF‐T‐252: Improvement of Localization Accuracy by Using 3D Cone Beam CT for Stereotactic Body Radiation Therapy of Liver, Lung and Spine Lesions

Conference Medical Physics · January 1, 2007 Purpose: To compare treatment isocenter placement based on OBI 2D kV imaging and OBI 3D‐CBCT imaging for patients undergoing SBRT, and compare the CBCT based isocenter shifts among liver, lung and spine lesions. Material and Methods: 119 SBRT fractions wer ... Full text Cite

TU‐EE‐A3‐03: Performing Concurrent Kilovoltage Imaging While Delivering Megavoltage Treatment Beams

Conference Medical Physics · January 1, 2007 Purpose: To investigate the clinical feasibility of performing concurrent kilovoltage (kV) x‐ray imaging while the patient at the treatment position was irradiated by megavoltage (MV) beams. Method and Materials: Anatomical visibility and contrast details ... Full text Cite

SU‐FF‐J‐68: Dosimetric Comparison of Patient‐Specific Margins Vs. Uniform Margins for Prostate IMRT Treatments

Conference Medical Physics · January 1, 2007 Purpose: To evaluate the dosimetric improvement of IMRT treatment plans generated with patient‐specific margins compared to uniform margins for prostate cancer patients. Methods and Materials: For 13 prostate cancer patients who underwent IMRT treatment, d ... Full text Cite

A quality assurance program for the on-board imager®

Conference IFMBE Proceedings · January 1, 2007 Purpose: To develop a comprehensive quality assurance (QA) program for the On-Board Imager (OBI) used for patient positioning verification and to present the results of QA tests over extended periods from multiple institutions. Radiographic and cone-beam c ... Full text Cite

SU‐FF‐T‐300: Monte Carlo Benchmark for Radiation Dose Assessment in Varian On‐Board Imager

Conference Medical Physics · January 1, 2007 Purpose: To evaluate radiation dose in kV cone‐beam computed tomography (CBCT) and to benchmark Monte Carlo (MC) simulations in the PMMA CT phantoms Method and Materials: Using an On‐Board Imager (Varian Medical Systems), we measured absorbed doses to the ... Full text Cite

Feasibility of cone-beam CT based treatment planning

Conference IFMBE Proceedings · January 1, 2007 Purpose: This study investigates feasibility of CBCT-based treatment planning. Methods and materials: Hounsfield unit (HU) values and profiles of phantoms and patients in CBCT images were compared to those in CT images. CBCT-based treatment plans for the p ... Full text Cite

SU‐FF‐J‐81: Estimation of Dose Variations During Prostate Radiation Treatment Due to Elastic Deformations of Soft Tissues

Conference Medical Physics · January 1, 2007 Objective: The true dose distribution is subject to change due to organ shifts and also deformations. The goal of this work is to estimate the effect of the elastic organ deformations on the dose distribution for the average prostate IMRT treatment. Method ... Full text Cite

Dosimetric feasibility of cone-beam CT-based treatment planning compared to CT-based treatment planning.

Journal Article Int J Radiat Oncol Biol Phys · December 1, 2006 Featured Publication PURPOSE: Cone-beam computed tomography (CBCT) images are currently used for positioning verification. However, it is yet unknown whether CBCT could be used in dose calculation for replanning in adaptive radiation therapy. This study investigates the dosime ... Full text Link to item Cite

A quality assurance program for the on-board imager®.

Journal Article Med Phys · November 2006 Featured Publication To develop a quality assurance (QA) program for the On-Board Imager (OBI) system and to summarize the results of these QA tests over extended periods from multiple institutions. Both the radiographic and cone-beam computed tomography (CBCT) mode of operati ... Full text Link to item Cite

Digital tomosynthesis with an on-board kilovoltage imaging device.

Journal Article Int J Radiat Oncol Biol Phys · May 1, 2006 PURPOSE: To generate on-board digital tomosynthesis (DTS) and reference DTS images for three-dimensional image-guided radiation therapy (IGRT) as an alternative to conventional portal imaging or on-board cone-beam computed tomography (CBCT). METHODS AND MA ... Full text Link to item Cite

WE‐E‐ValA‐03: Dosimetric Evaluation of Prostate IMRT Treatments Positioned Based On Cone‐Beam CT

Conference Medical Physics · January 1, 2006 Purpose: To evaluate the dosimetric consequence of 3D positioning verification for prostate IMRT treatment using CBCT. Method and Materials: Patients in this study were repositioned using 2D orthogonal radiographic images, taken prior to treatment to match ... Full text Cite

SU‐FF‐T‐334: Moving From Measurements Toward Independent Computer Calculations for Patient‐Specific IMRT QA

Conference Medical Physics · January 1, 2006 Purpose: A medical physicist's time and resources are always balanced between many clinical obligations. It would be advantageous for physicists to forgo measurements of IMRT plans in lieu of independent computer calculations. In this work, we investigate ... Full text Cite

SU‐FF‐T‐66: A Technique for Cone‐Beam CT‐Guided Stereotactic Body Radiation Therapy

Conference Medical Physics · January 1, 2006 Purpose: To develop and assess a technique using cone‐beam CT (CBCT) to localize treatment targets for stereotactic body radiation therapy (SBRT). Material and Methods: Patients selected for SBRT had 3‐D or 4‐D CT simulation with immobilization. GTV, CTV, ... Full text Cite

SU‐FF‐J‐22: An Image Based Statistical Shape Model and Its Application in Radiotherapy Margin Design

Conference Medical Physics · January 1, 2006 Purpose: A novel imaging based model is proposed to describe the stochastic nature of the shape and location of a volume of interest (VOI). Based on the VOIs in sequential patient images, the model can predict the probability that a specific point will bel ... Full text Cite

SU‐FF‐I‐17: Reduction of Set‐Up Error Using Cone Beam‐CT in Patients Undergoing Partial Breast Irradiation

Conference Medical Physics · January 1, 2006 Purpose: Partial breast irradiation with multiple external beams requires accurate alignment of the target volume and treatment isocenter. On‐board plannar kV/MV imaging can verify set‐up based on boney landmarks. On‐board cone beam CT (CBCT) may provide a ... Full text Cite

SU‐EE‐A1‐04: Verifying Internal Target Volume Using Cone‐Beam CT for Stereotactic Body Radiotherapy Treatment

Conference Medical Physics · January 1, 2006 Purpose: The internal target volume (ITV) could be determined using 4D CT simulation images and be verified in the treatment room using on‐board cone‐beam CT (CBCT) since the CBCT projection images are acquired over approximately 10 breathing cycles. This ... Full text Cite

SU‐FF‐J‐86: Intra‐ and Inter‐Breath‐Hold Position Variations for OBI Guided Amplitude Gating Treatment with Breath Hold

Conference Medical Physics · January 1, 2006 Purpose: We have applied OBI guidance together with a respiratory gating system to effectively control patient positioning for amplitude gating treatment with breath hold. The deep inspiration breath‐hold treatment has been proven effective in reducing the ... Full text Cite

MO‐A‐224C‐01: Daily Localization I: KV/CBCT

Conference Medical Physics · January 1, 2006 Daily target localization is a critical step to secure accurate delivery for 3‐D conformal radiation therapy and intensity‐modulated radiation therapy. One emerging technology using in‐room kilovoltage (kV) imaging has shown to be very promising for target ... Full text Cite

SU‐FF‐J‐16: A Tool for Off‐Line Review of 3D Target Verification and Localization with Cone‐Beam Computed Tomography

Conference Medical Physics · January 1, 2006 Purpose: To implement a clinical tool for off‐line review of Cone‐Beam Computed Tomography (CBCT) based 3D target verification and localization. Methods and Materials: An in‐house 3D target localization and verification tool is being developed to allow phy ... Full text Cite

SU‐FF‐T‐374: Quality Assurance of the On‐Board Imager and Cone‐Beam Computed Tomography Systems

Conference Medical Physics · January 1, 2006 Purpose: To develop a comprehensive quality assurance (QA) program for the On‐Board Imager (OBI) used for patient positioning verification and to present the results of QA tests over extended periods from multiple institutions. Radiographic and cone‐beam c ... Full text Cite

TU‐FF‐A2‐01: Feasibility of Cone‐Beam CT Based Treatment Planning

Conference Medical Physics · January 1, 2006 Purpose: To investigate the feasibility of cone‐beam computed tomography (CBCT)‐based treatment planning. Methods: HU of material disks in Catphan, HU profiles for homogeneous and inhomogeneous phantoms, and HU values in different tissue areas of brain, th ... Full text Cite

SU‐FF‐T‐212: Quality Assurance (QA) Procedure of On‐Board Imager (OBI) for Portal Imaging

Journal Article Medical Physics · January 1, 2005 Purpose: On‐board imager (OBI) has been implemented to improve the in‐room patient positioning. It is therefore important to establish quality assurance (QA) procedure to ensure proper functionality and operational accuracy. This report presents monthly OB ... Full text Cite

SU‐FF‐T‐186: Commissioning of Tissue Inhomogeneity Correction of Eclipse Radiation Treatment Planning System Using a Lung Phantom

Conference Medical Physics · January 1, 2005 Purpose: It has been noted that dosimetric difference due to tissue inhomogeneity is significant for a lung patient. If there is no tissue inhomogeneity correction (IC) made, the treatment plan could mislead treatment. Commercial radiation treatment planni ... Full text Cite

SU‐FF‐J‐80: Clinical Procedures for Daily Patient Setup Verification Using On‐Board Imager (OBI)

Conference Medical Physics · January 1, 2005 Purpose: The newly installed OBI system consists of a kilo‐voltage (KV) X‐ray source and a flat‐ panel detector mounted orthogonally to the megavoltage portal imager (MV) in Varian 21EX machine. These devices are linked to the OBI workstation which provide ... Full text Cite

Treatment planning for prostate brachytherapy using region of interest adjoint functions and a greedy heuristic.

Journal Article Phys Med Biol · December 21, 2003 We have developed an efficient treatment-planning algorithm for prostate implants that is based on region of interest (ROI) adjoint functions and a greedy heuristic. For this work, we define the adjoint function for an ROI as the sensitivity of the average ... Full text Link to item Cite

Characteristics of sensitometric curves of radiographic films.

Journal Article Med Phys · May 2003 A new type of radiographic film, EDR (extended dose range) film, has been recently become available for film dosimetry. It is particularly attractive for composite isodose verification of intensity modulated radiation therapy because of its low sensitivity ... Full text Link to item Cite

Clinical implementation of AAPM TG61 protocol for kilovoltage x-ray beam dosimetry.

Journal Article Med Phys · October 2002 Historically, there have been a variety of dosimetry protocols used for kilovoltage x-ray therapy beams with a set of conversion factors and correction factors taken from different references. Corresponding to the continued installation and use of kilovolt ... Full text Link to item Cite