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Tomi Akinyemiju

Professor in Population Health Sciences
Population Health Sciences
215 Morris St Ste 210, PO Box 104023, Durham, NC 27701

Selected Publications


Frailty in patients with ovarian cancer and the role of healthcare access, race, and ethnicity.

Journal Article Gynecol Oncol · August 29, 2024 OBJECTIVE: Ovarian cancer has poor 5-year survival, particularly among non-Hispanic (NH) Black patients. Efforts to identify patients at high-risk of functional limitations and frailty may improve outcomes. In this study, we examined how healthcare access ... Full text Link to item Cite

Early-onset cancer incidence in the United States by race/ethnicity between 2011 and 2020.

Journal Article Cancer Epidemiol · August 1, 2024 We characterized trends in early onset (aged 20-49) cancer incidence by race/ethnicity and sex using the 2011-2020 Surveillance, Epidemiology, and End Results (SEER) Program dataset. We estimated age-standardized cancer incidence rates, incidence rate rati ... Full text Link to item Cite

Neighborhood-level socioeconomic disparities in Radon testing in North Carolina from 2010 to 2020.

Journal Article J Environ Radioact · July 2024 Radon is a naturally occurring radioactive gas that poses significant health risks to humans, including increased risk of lung cancer. This study investigates the association of neighborhood-level socioeconomic variables with radon testing and radon exposu ... Full text Link to item Cite

Racial and ethnic disparities in genomic testing among lung cancer patients: a systematic review.

Journal Article J Natl Cancer Inst · June 7, 2024 BACKGROUND: Racial and ethnic disparities in genomic testing could exacerbate disparities in access to precision cancer therapies and survival-particularly in the context of lung cancer where genomic testing has been recommended for the past decade. Howeve ... Full text Open Access Link to item Cite

Characterizing Cancer Burden in the American Indian Population in North Carolina.

Journal Article Cancer Epidemiol Biomarkers Prev · June 3, 2024 BACKGROUND: The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer population and examine AI-White dis ... Full text Link to item Cite

Supplemental Table S1 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Table S1: Clinical and sociodemographic characteristics of Non-Hispanic American Indian in PRCDA counties and Non-Hispanic White cancer cases diagnosed between 2014-2018 (n=206,774)</p> ... Full text Cite

Supplemental Table S2 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Table S2: Comparison of clinical and sociodemographic characteristics across American Indian classifications for persons diagnosed with cancer between 2014-2018</p> ... Full text Cite

Data from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <div>AbstractBackground:<p>The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer ... Full text Cite

Data from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <div>AbstractBackground:<p>The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer ... Full text Cite

Supplemental Figure S1 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Figure S1: Standardized incidence estimates per 100k across classifications of American Indian persons</p> ... Full text Cite

Supplemental Table S2 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Table S2: Comparison of clinical and sociodemographic characteristics across American Indian classifications for persons diagnosed with cancer between 2014-2018</p> ... Full text Cite

Supplemental Figure S1 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Figure S1: Standardized incidence estimates per 100k across classifications of American Indian persons</p> ... Full text Cite

Supplemental Table S1 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Table S1: Clinical and sociodemographic characteristics of Non-Hispanic American Indian in PRCDA counties and Non-Hispanic White cancer cases diagnosed between 2014-2018 (n=206,774)</p> ... Full text Cite

Racial Differences in Vaginal Fluid Metabolites and Association with Systemic Inflammation Markers among Ovarian Cancer Patients: A Pilot Study.

Journal Article Cancers (Basel) · March 23, 2024 The vaginal microbiome differs by race and contributes to inflammation by directly producing or consuming metabolites or by indirectly inducing host immune response, but its potential contributions to ovarian cancer (OC) disparities remain unclear. In this ... Full text Link to item Cite

Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer.

Journal Article Cancer Res Commun · March 18, 2024 UNLABELLED: This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients with ovarian cancer. Th ... Full text Link to item Cite

TABLE 2 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Estimates of the associations between HCA dimensions, patient race and ethnicity, and EOL care quality outcomes on entire study cohort (<i>N</i> = 4,646), subcohort of patients that died from ovarian cancer (<i>N</i&gt ... Full text Cite

TABLE 1 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Baseline characteristics of patients with ovarian cancer who died during study follow-up stratified by race and ethnicity (<i>N</i> = 4,646)</p> ... Full text Cite

Supplementary Table 5 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Relative risk ratio (RR) for receipt of any chemotherapy within 14 days of death with interaction term between accessibility score and patient race</p> ... Full text Cite

TABLE 1 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Baseline characteristics of patients with ovarian cancer who died during study follow-up stratified by race and ethnicity (<i>N</i> = 4,646)</p> ... Full text Cite

Frailty in patients with ovarian cancer and the role of healthcare access, race, and ethnicity.

Journal Article Gynecol Oncol · August 29, 2024 OBJECTIVE: Ovarian cancer has poor 5-year survival, particularly among non-Hispanic (NH) Black patients. Efforts to identify patients at high-risk of functional limitations and frailty may improve outcomes. In this study, we examined how healthcare access ... Full text Link to item Cite

Early-onset cancer incidence in the United States by race/ethnicity between 2011 and 2020.

Journal Article Cancer Epidemiol · August 1, 2024 We characterized trends in early onset (aged 20-49) cancer incidence by race/ethnicity and sex using the 2011-2020 Surveillance, Epidemiology, and End Results (SEER) Program dataset. We estimated age-standardized cancer incidence rates, incidence rate rati ... Full text Link to item Cite

Neighborhood-level socioeconomic disparities in Radon testing in North Carolina from 2010 to 2020.

Journal Article J Environ Radioact · July 2024 Radon is a naturally occurring radioactive gas that poses significant health risks to humans, including increased risk of lung cancer. This study investigates the association of neighborhood-level socioeconomic variables with radon testing and radon exposu ... Full text Link to item Cite

Racial and ethnic disparities in genomic testing among lung cancer patients: a systematic review.

Journal Article J Natl Cancer Inst · June 7, 2024 BACKGROUND: Racial and ethnic disparities in genomic testing could exacerbate disparities in access to precision cancer therapies and survival-particularly in the context of lung cancer where genomic testing has been recommended for the past decade. Howeve ... Full text Open Access Link to item Cite

Characterizing Cancer Burden in the American Indian Population in North Carolina.

Journal Article Cancer Epidemiol Biomarkers Prev · June 3, 2024 BACKGROUND: The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer population and examine AI-White dis ... Full text Link to item Cite

Supplemental Table S1 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Table S1: Clinical and sociodemographic characteristics of Non-Hispanic American Indian in PRCDA counties and Non-Hispanic White cancer cases diagnosed between 2014-2018 (n=206,774)</p> ... Full text Cite

Supplemental Table S2 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Table S2: Comparison of clinical and sociodemographic characteristics across American Indian classifications for persons diagnosed with cancer between 2014-2018</p> ... Full text Cite

Data from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <div>AbstractBackground:<p>The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer ... Full text Cite

Data from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <div>AbstractBackground:<p>The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer ... Full text Cite

Supplemental Figure S1 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Figure S1: Standardized incidence estimates per 100k across classifications of American Indian persons</p> ... Full text Cite

Supplemental Table S2 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Table S2: Comparison of clinical and sociodemographic characteristics across American Indian classifications for persons diagnosed with cancer between 2014-2018</p> ... Full text Cite

Supplemental Figure S1 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Figure S1: Standardized incidence estimates per 100k across classifications of American Indian persons</p> ... Full text Cite

Supplemental Table S1 from Characterizing Cancer Burden in the American Indian Population in North Carolina

Other · June 3, 2024 <p>Supplemental Table S1: Clinical and sociodemographic characteristics of Non-Hispanic American Indian in PRCDA counties and Non-Hispanic White cancer cases diagnosed between 2014-2018 (n=206,774)</p> ... Full text Cite

Racial Differences in Vaginal Fluid Metabolites and Association with Systemic Inflammation Markers among Ovarian Cancer Patients: A Pilot Study.

Journal Article Cancers (Basel) · March 23, 2024 The vaginal microbiome differs by race and contributes to inflammation by directly producing or consuming metabolites or by indirectly inducing host immune response, but its potential contributions to ovarian cancer (OC) disparities remain unclear. In this ... Full text Link to item Cite

Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer.

Journal Article Cancer Res Commun · March 18, 2024 UNLABELLED: This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients with ovarian cancer. Th ... Full text Link to item Cite

TABLE 2 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Estimates of the associations between HCA dimensions, patient race and ethnicity, and EOL care quality outcomes on entire study cohort (<i>N</i> = 4,646), subcohort of patients that died from ovarian cancer (<i>N</i&gt ... Full text Cite

TABLE 1 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Baseline characteristics of patients with ovarian cancer who died during study follow-up stratified by race and ethnicity (<i>N</i> = 4,646)</p> ... Full text Cite

Supplementary Table 5 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Relative risk ratio (RR) for receipt of any chemotherapy within 14 days of death with interaction term between accessibility score and patient race</p> ... Full text Cite

TABLE 1 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Baseline characteristics of patients with ovarian cancer who died during study follow-up stratified by race and ethnicity (<i>N</i> = 4,646)</p> ... Full text Cite

FIGURE 1 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Participant flowchart for NHB, Hispanic and NHW patients with ovarian cancer, SEER-Medicare 2008–2015. Percentage of NHB patients presented for sensitivity purposes.</p> ... Full text Cite

TABLE 3 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Adjusted count ratio estimates of the associations between HCA dimensions, patient race and ethnicity, and counts of EOL care quality outcomes as count ratios, from fully-adjusted<a href="#tb3fn1" target="_blank"><sup>a</sup ... Full text Cite

Supplementary Table 1 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Patient, census tract, and regional level variables measuring dimensions of healthcare affordability, availability and accessibility</p> ... Full text Cite

TABLE 3 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Adjusted count ratio estimates of the associations between HCA dimensions, patient race and ethnicity, and counts of EOL care quality outcomes as count ratios, from fully-adjusted<a href="#tb3fn1" target="_blank"><sup>a</sup ... Full text Cite

Supplementary Table 4 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Relative risk ratio estimates of the associations between HCA dimensions, patient race/ethnicity, and EOL care quality outcomes</p> ... Full text Cite

Supplementary Table 5 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Relative risk ratio (RR) for receipt of any chemotherapy within 14 days of death with interaction term between accessibility score and patient race</p> ... Full text Cite

Data from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <div>Abstract<p>This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients ... Full text Cite

TABLE 2 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Estimates of the associations between HCA dimensions, patient race and ethnicity, and EOL care quality outcomes on entire study cohort (<i>N</i> = 4,646), subcohort of patients that died from ovarian cancer (<i>N</i&gt ... Full text Cite

Supplementary Table 4 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Relative risk ratio estimates of the associations between HCA dimensions, patient race/ethnicity, and EOL care quality outcomes</p> ... Full text Cite

Data from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <div>Abstract<p>This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients ... Full text Cite

FIGURE 1 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Participant flowchart for NHB, Hispanic and NHW patients with ovarian cancer, SEER-Medicare 2008–2015. Percentage of NHB patients presented for sensitivity purposes.</p> ... Full text Cite

FIGURE 2 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>EOL care quality outcomes by patient race and ethnicity (<i>N</i> = 4,646). ICU stay and ER visit outcomes not shown due to cell suppression rules. Outcomes that differ by patient race/ethnicity (<i>χ</i><sup> ... Full text Cite

FIGURE 2 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>EOL care quality outcomes by patient race and ethnicity (<i>N</i> = 4,646). ICU stay and ER visit outcomes not shown due to cell suppression rules. Outcomes that differ by patient race/ethnicity (<i>χ</i><sup> ... Full text Cite

Supplementary Table 1 from Health Care Access Dimensions and Racial Disparities in End-of-Life Care Quality among Patients with Ovarian Cancer

Other · March 18, 2024 <p>Patient, census tract, and regional level variables measuring dimensions of healthcare affordability, availability and accessibility</p> ... Full text Cite

Racial and socioeconomic disparities in survival among women with advanced-stage ovarian cancer who received systemic therapy.

Journal Article Cancer Causes Control · March 2024 PURPOSE: The purpose of this study was to assess the association between race/ethnicity and all-cause mortality among women with advanced-stage ovarian cancer who received systemic therapy. METHODS: We analyzed data from the National Cancer Database on wom ... Full text Link to item Cite

Association of reproductive risk factors and breast cancer molecular subtypes: a systematic review and meta-analysis.

Journal Article BMC Cancer · July 10, 2023 BACKGROUND: Associations between reproductive factors and breast cancer (BC) risk vary by molecular subtype (i.e., luminal A, luminal B, HER2, and triple negative/basal-like [TNBC]). In this systematic review and meta-analysis, we summarized the associatio ... Full text Link to item Cite

Socioeconomic disparities in immunotherapy use among advanced-stage non-small cell lung cancer patients: analysis of the National Cancer Database.

Journal Article Sci Rep · May 20, 2023 Socioeconomic and racial disparities exist in access to care among patients with non-small cell lung cancer (NSCLC) in the United States. Immunotherapy is a widely established treatment modality for patients with advanced-stage NSCLC (aNSCLC). We examined ... Full text Link to item Cite

The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study.

Journal Article Cancer Epidemiol Biomarkers Prev · April 3, 2023 BACKGROUND: Head and neck cancer (HNC) mortality differs by race, ethnicity, and socioeconomic status (SES). However, it is unclear whether the relationship between race/ethnicity and HNC-specific mortality varies according to the residence-level SES. METH ... Full text Link to item Cite

Supplementary Table S4 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S4 shows the joint association between race/ethnicity and socioeconomic status and mortality.</p> ... Full text Cite

Data from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <div>AbstractBackground:<p>Head and neck cancer (HNC) mortality differs by race, ethnicity, and socioeconomic status (SES). However, it is unclear whether the relationship between race/ethnicity and HNC-specific mortality varies accordi ... Full text Cite

Supplementary Table S2 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S2 shows demographic and clinical characteristics of patients with primary head and neck cancer by race/ethnicity with missing socioeconomic status.</p> ... Full text Cite

Supplementary Table S1 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S1 shows descriptive statistics of primary head and neck cancer patients with survival time <12 Months by race/ethnicity.</p> ... Full text Cite

Supplementary Table S4 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S4 shows the joint association between race/ethnicity and socioeconomic status and mortality.</p> ... Full text Cite

Supplementary Table S3 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S3 shows demographic and clinical characteristics of patients with primary head and neck cancer by socioeconomic status.</p> ... Full text Cite

Supplementary Figure S2 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Figure S2 shows cumulative incidence curves by socioeconomic status for the HNC-specific death by race/ethnicity.</p> ... Full text Cite

Supplementary Table S3 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S3 shows demographic and clinical characteristics of patients with primary head and neck cancer by socioeconomic status.</p> ... Full text Cite

Supplementary Table S6 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S6a shows the Cox proportional hazards model for laryngeal cancer, stratified by race/ethnicity and socioeconomic status. Table S6b shows the Cox proportional hazards model for sinonasal cancers, stratified by race/ethnicity and soci ... Full text Cite

Supplementary Table S1 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S1 shows descriptive statistics of primary head and neck cancer patients with survival time <12 Months by race/ethnicity.</p> ... Full text Cite

Supplementary Table S5 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S5a shows the Cox proportional hazards model for oral cavity cancer, stratified by race/ethnicity and socioeconomic status. Table S5b shows the Cox proportional hazards model for pharyngeal cancers, stratified by race/ethnicity and s ... Full text Cite

Supplementary Table S5 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S5a shows the Cox proportional hazards model for oral cavity cancer, stratified by race/ethnicity and socioeconomic status. Table S5b shows the Cox proportional hazards model for pharyngeal cancers, stratified by race/ethnicity and s ... Full text Cite

Supplementary Figure S2 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Figure S2 shows cumulative incidence curves by socioeconomic status for the HNC-specific death by race/ethnicity.</p> ... Full text Cite

Supplementary Table S2 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S2 shows demographic and clinical characteristics of patients with primary head and neck cancer by race/ethnicity with missing socioeconomic status.</p> ... Full text Cite

Supplementary Table S6 from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <p>Table S6a shows the Cox proportional hazards model for laryngeal cancer, stratified by race/ethnicity and socioeconomic status. Table S6b shows the Cox proportional hazards model for sinonasal cancers, stratified by race/ethnicity and soci ... Full text Cite

Data from The Intersectionality between Race, Ethnicity, and Residential-Level Socioeconomic Status in Disparities of Head and Neck Cancer Outcomes: A SEER Study

Other · April 3, 2023 <div>AbstractBackground:<p>Head and neck cancer (HNC) mortality differs by race, ethnicity, and socioeconomic status (SES). However, it is unclear whether the relationship between race/ethnicity and HNC-specific mortality varies accordi ... Full text Cite

Racial and ethnic inequities of palliative care use among advanced Non-Small cell lung cancer patients in the US.

Journal Article Cancer Med · April 2023 BACKGROUND: With early intervention, palliative care (PC) can improve quality of life and increase survival among advanced-stage non-small cell lung cancer (aNCSLC) patients. However, PC is often offered late in the cancer treatment course and is underused ... Full text Link to item Cite

Association between peripheral blood cytopenia and cancer mortality: A race-specific risk factor for cancer death.

Journal Article Cancer Med · April 2023 BACKGROUND: Cytopenia is associated with cancer through mechanisms including clonal hematopoiesis and chronic inflammation. Cytopenia is more prevalent in Black people but its relationship with racial disparities in cancer mortality is unknown. METHODS: Cy ... Full text Link to item Cite

Health-care access dimensions and ovarian cancer survival: SEER-Medicare analysis of the ORCHiD study.

Journal Article JNCI Cancer Spectr · March 1, 2023 BACKGROUND: Racial and ethnic disparities in ovarian cancer (OC) survival are well-documented. However, few studies have investigated how health-care access (HCA) contributes to these disparities. METHODS: To evaluate the influence of HCA on OC mortality, ... Full text Link to item Cite

Healthcare Access Domains Mediate Racial Disparities in Ovarian Cancer Treatment Quality in a US Patient Cohort: A Structural Equation Modelling Analysis.

Journal Article Cancer Epidemiol Biomarkers Prev · January 9, 2023 BACKGROUND: Ovarian cancer survival disparities have persisted for decades, driven by lack of access to quality treatment. We conducted structural equation modeling (SEM) to define latent variables representing three healthcare access (HCA) domains: afford ... Full text Link to item Cite

Development and Psychometric Evaluation of Healthcare Access Measures among Women with Ovarian Cancer.

Journal Article Cancers (Basel) · December 19, 2022 Several proposed theoretical frameworks have defined the complex nature of healthcare access (HCA) [...]. ... Full text Link to item Cite

Race, Affordability and Utilization of Supportive Care in Ovarian Cancer Patients.

Journal Article J Pain Symptom Manage · December 2022 OBJECTIVE: Lack of access to supportive care (SC) among cancer patients have been well documented. However, the role of affordability in this disparity among ovarian cancer (OC) patients remain poorly understood. METHODS: Patients with OC between 2008 and ... Full text Link to item Cite

Palliative Care Use among People Living with HIV and Cancer: An Analysis of the National Cancer Database (2004-2018)

Conference JCO Oncology Practice · October 1, 2022 PURPOSE:People living with HIV (PLWH) diagnosed with cancer are less likely to receive quality cancer treatment compared with HIV-negative patients. Timely provision of palliative care (PC) during cancer treatment can increase patient's survival and improv ... Full text Cite

Palliative Care Use Among People Living With HIV and Cancer: An Analysis of the National Cancer Database (2004-2018).

Journal Article JCO Oncol Pract · October 2022 PURPOSE: People living with HIV (PLWH) diagnosed with cancer are less likely to receive quality cancer treatment compared with HIV-negative patients. Timely provision of palliative care (PC) during cancer treatment can increase patient's survival and impro ... Full text Link to item Cite

Association of area-level socioeconomic status and non-small cell lung cancer stage by race/ethnicity and health care-level factors: Analysis of the National Cancer Database.

Journal Article Cancer · August 15, 2022 BACKGROUND: This study examined whether the association of socioeconomic status (SES) and non-small cell lung cancer (NSCLC) stage varied by race/ethnicity and health care access measures. METHODS: This study used data from the 2004-2016 National Cancer Da ... Full text Link to item Cite

Associations of Healthcare Affordability, Availability, and Accessibility with Quality Treatment Metrics in Patients with Ovarian Cancer.

Journal Article Cancer Epidemiol Biomarkers Prev · July 1, 2022 BACKGROUND: Differential access to quality care is associated with racial disparities in ovarian cancer survival. Few studies have examined the association of multiple healthcare access (HCA) dimensions with racial disparities in quality treatment metrics, ... Full text Link to item Cite

Association of lipid profile biomarkers with breast cancer by molecular subtype: analysis of the MEND study.

Journal Article Sci Rep · June 23, 2022 There is conflicting evidence on the role of lipid biomarkers in breast cancer (BC), and no study to our knowledge has examined this association among African women. We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) for the association o ... Full text Link to item Cite

Metabolic Syndrome and Risk of Breast Cancer by Molecular Subtype: Analysis of the MEND Study.

Journal Article Clin Breast Cancer · June 2022 BACKGROUND: Metabolic syndrome (MetS) is characterized by a cluster of biological irregularities. The purpose of this analysis was to examine the association of MetS with BC among Nigerian women, and for the first time evaluate this association by molecula ... Full text Link to item Cite

Racial Differences in Survival Among Advanced-stage Non-small-Cell Lung Cancer Patients Who Received Immunotherapy: An Analysis of the US National Cancer Database (NCDB).

Journal Article J Immunother · February 2022 Lung cancer is the most common cause of cancer death among men and women in the United States, with significant racial disparities in survival. It is unclear whether these disparities persist upon equal utilization of immunotherapy. The purpose of this stu ... Full text Link to item Cite

Social determinants of health and cancer mortality in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort study.

Journal Article Cancer · January 1, 2022 BACKGROUND: Social determinants of health (SDOHs) cluster together and can have deleterious impacts on health outcomes. Individually, SDOHs increase the risk of cancer mortality, but their cumulative burden is not well understood. The authors sought to det ... Full text Link to item Cite

Association of aflatoxin B1 levels with mean CD4 cell count and uptake of ART among HIV infected patients: A prospective study.

Journal Article PLoS One · 2022 BACKGROUND: Aflatoxin suppresses cellular immunity and accentuates HIV-associated changes in T- cell phenotypes and B- cells. OBJECTIVE: This prospective study was conducted to examine the association of aflatoxin levels with CD4 T-cell count and antiretro ... Full text Link to item Cite

Abstract PO-107: Racial differences in survival among advanced-stage non-small cell lung cancer patients who received immunotherapy: An analysis of the U.S. National Cancer Database (NCDB)

Conference Cancer Epidemiology, Biomarkers & Prevention · January 1, 2022 AbstractBackground: Lung cancer is the most common cause of cancer death among men and women in the United States, with 85% of all cases characterized as non-small cell lung cancer (NSCLC). These cancers are ... Full text Cite

Abstract PO-113: Overall survival in ovarian cancer patients seeking care at more than one treatment facility

Conference Cancer Epidemiology, Biomarkers & Prevention · January 1, 2022 AbstractPurpose: Ovarian cancer is the most lethal gynecological cancer and despite advances in treatment, most patients are diagnosed at an advanced stage with poor prognosis. Black women have a lower 5 yea ... Full text Cite

Abstract PO-178: Metabolic syndrome and risk of breast cancer by molecular subtype: Analysis of the Mechanisms for Novel and Established Risk Factors for Breast Cancer in Women of Nigerian Descent (MEND) study

Conference Cancer Epidemiology, Biomarkers & Prevention · January 1, 2022 AbstractBackground: The African continent experiences the highest age-standardized breast cancer mortality globally, with Nigeria reporting the highest rate within the continent. Breast cancer in Nigeria is ... Full text Cite

A Socio-Ecological Framework for Cancer Prevention in Low and Middle-Income Countries.

Journal Article Front Public Health · 2022 Cancer incidence and mortality rates continue to rise globally, a trend mostly driven by preventable cancers occurring in low-and middle-income countries (LMICs). There is growing concern that many LMICs are ill-equipped to cope with markedly increased bur ... Full text Link to item Cite

Early Medicaid Expansion and Cancer Mortality.

Journal Article J Natl Cancer Inst · November 29, 2021 BACKGROUND: Although Medicaid expansion is associated with decreased uninsured rates and earlier cancer diagnoses, no study has demonstrated an association between Medicaid expansion and cancer mortality. Our primary objective was to quantify the relations ... Full text Link to item Cite

Comorbidity Profiles and Lung Cancer Screening among Older Adults: U.S. Behavioral Risk Factor Surveillance System 2017-2019.

Journal Article Ann Am Thorac Soc · November 2021 Rationale: Although lung cancer screening (LCS) with low-dose computed tomography (LDCT) is now recommended for those meeting standard risk factor-based eligibility criteria, the role of comorbidity in the uptake of LCS with LDCT in an older real-world U.S ... Full text Link to item Cite

Ovarian Cancer Epidemiology, Healthcare Access and Disparities (ORCHiD): methodology for a population-based study of black, Hispanic and white patients with ovarian cancer.

Journal Article BMJ Open · October 4, 2021 INTRODUCTION: Less than 40% of patients with ovarian cancer (OC) in the USA receive stage-appropriate guideline-adherent surgery and chemotherapy. Black patients with cancer report greater depression, pain and fatigue than white patients. Lack of access to ... Full text Link to item Cite

Association of genetic variants of FBXO32 and FOXO6 in the FOXO pathway with breast cancer risk.

Journal Article Mol Carcinog · October 2021 Forkhead box class O (FOXO) transcription factors play a pivotal role in regulating a variety of biological processes, including organismal development, cell signaling, cell metabolism, and tumorigenesis. Therefore, we hypothesize that genetic variants in ... Full text Open Access Link to item Cite

Association of body composition with odds of breast cancer by molecular subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Nigerian Women (MEND) study.

Journal Article BMC Cancer · September 25, 2021 BACKGROUND: The association between obesity and breast cancer (BC) has been extensively studied among US, European and Asian study populations, with often conflicting evidence. However, despite the increasing prevalence of obesity and associated conditions ... Full text Link to item Cite

A novel evolutionary-concordance lifestyle score is inversely associated with all-cause, all-cancer, and all-cardiovascular disease mortality risk.

Journal Article Eur J Nutr · September 2021 PURPOSE: Evolutionary discordance may contribute to the high burden of chronic disease-related mortality in modern industrialized nations. We aimed to investigate the associations of a 7-component, equal-weight, evolutionary-concordance lifestyle (ECL) sco ... Full text Link to item Cite

Association of high-sensitivity C-reactive protein and odds of breast cancer by molecular subtype: analysis of the MEND study.

Journal Article Oncotarget · June 22, 2021 Breast cancer (BC) in Nigeria is characterized by disproportionately aggressive molecular subtypes. C-reactive protein (CRP) is associated with risk and aggressiveness for several types of cancer. We examined the association of high-sensitivity CRP (hsCRP) ... Full text Link to item Cite

Health Care Access Measures and Palliative Care Use by Race/Ethnicity among Metastatic Gynecological Cancer Patients in the United States.

Journal Article Int J Environ Res Public Health · June 4, 2021 Palliative care improves quality-of-life and extends survival, however, is underutilized among gynecological cancer patients in the United States (U.S.). Our objective was to evaluate associations between healthcare access (HCA) measures and palliative car ... Full text Link to item Cite

Use of therapeutic plasma exchange in heparin-induced thrombocytopenia: A population-based study.

Journal Article J Clin Apher · June 2021 BACKGROUND: Heparin-induced thrombocytopenia (HIT) is characterized by anti-heparin/platelet factor 4 immune complexes, which are removed by therapeutic plasma exchange (TPE). Our main objective was to study TPE outcomes in HIT using a large administrative ... Full text Open Access Link to item Cite

Temporal changes in allostatic load patterns by age, race/ethnicity, and gender among the US adult population; 1988-2018.

Journal Article Prev Med · June 2021 The objective of this study is to provide an assessment of allostatic load (AL) burden among US adults across race/ethnicity, gender, and age groups over a 30-year time period. We analyzed data from 50,671 participants of the National Health and Nutrition ... Full text Link to item Cite

Immunotherapy Utilization Among Patients With Metastatic NSCLC: Impact of Comorbidities.

Journal Article J Immunother · June 1, 2021 In patients with metastatic non-small cell lung cancer (mNSCLC), the extent to which immunotherapy utilization rate varies by comorbidities is unclear. Using the National Cancer Database from 2015 to 2016, we assessed the association between levels of como ... Full text Link to item Cite

Patterns of de-novo metastasis and breast cancer-specific mortality by race and molecular subtype in the SEER population-based dataset.

Journal Article Breast Cancer Res Treat · April 2021 PURPOSE: To examine patterns of de-novo metastases (mets) and association with breast cancer-specific mortality across subtypes and racial groups. METHODS: Non-Hispanic (NH) Black and NH-White patients ages 40 years and older with primary breast cancer (BC ... Full text Link to item Cite

Association of Lipid Profile Biomarkers with Breast Cancer by Molecular Subtype: analysis of the Mechanisms for Established and Novel Risk Factors for Breast Cancer in Women of African Descent (MEND) study

Journal Article · March 10, 2021 AbstractPurpose: There is conflicting evidence on the role of lipid biomarkers in breast cancer (BC), and no study to our knowledge has examined this association among African women. Full text Cite

Racial and ethnic disparities in palliative care utilization among gynecological cancer patients.

Journal Article Gynecol Oncol · February 2021 BACKGROUND: Palliative care (PC) is recommended for gynecological cancer patients to improve survival and quality-of-life. Our objective was to evaluate racial/ethnic disparities in PC utilization among patients with metastatic gynecologic cancer. METHODS: ... Full text Link to item Cite

Racial disparities in palliative care utilization among metastatic gynecological cancer patients living at last follow-up: An analysis of the National Cancer Data Base.

Journal Article Data Brief · February 2021 The National Comprehensive Cancer Network recommends palliative care should be integrated in to cancer care starting from cancer diagnosis. However, traditionally palliative care is prioritized for cancer patients at the end-of-life. In our main article ti ... Full text Link to item Cite

Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems.

Journal Article BMC Med · January 8, 2021 BACKGROUND: Human immunodeficiency virus (HIV) remains a public health priority in Latin America. While the burden of HIV is historically concentrated in urban areas and high-risk groups, subnational estimates that cover multiple countries and years are mi ... Full text Link to item Cite

Mapping routine measles vaccination in low- and middle-income countries.

Journal Article Nature · January 2021 The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income ... Full text Link to item Cite

Socio-Economic and Rural-Urban Differences in Healthcare and Catastrophic Health Expenditure Among Cancer Patients in China: Analysis of the China Health and Retirement Longitudinal Study.

Journal Article Front Public Health · 2021 Objective: In China, cancer accounts for one-fifth of all deaths, and exerts a heavy toll on patients, families, healthcare systems, and society as a whole. This study aims to examine the temporal trends in socio-economic and rural-urban differences in tre ... Full text Link to item Cite

Association of Life-Course Educational Attainment and Breast Cancer Grade in the MEND Study.

Journal Article Ann Glob Health · 2021 BACKGROUND: Nigeria reports the highest age-standardized mortality rate for breast cancer (BC) among African countries and disproportionately high rates of high-grade cancer. Histological grade is a strong predictor of mortality, and evidence suggests that ... Full text Link to item Cite

A Prospective Study of Community Mediators on the Risk of Sepsis After Cancer.

Journal Article J Intensive Care Med · December 2020 BACKGROUND: Few studies have examined whether community factors mediate the relationship between patients surviving cancer and future development of sepsis. We determined the influence of community characteristics upon risk of sepsis after cancer, and whet ... Full text Link to item Cite

Five insights from the Global Burden of Disease Study 2019.

Journal Article Lancet · October 17, 2020 The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 ... Full text Open Access Link to item Cite

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019.

Journal Article Lancet · October 17, 2020 BACKGROUND: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study ... Full text Link to item Cite

Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Journal Article Lancet · October 17, 2020 BACKGROUND: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries ... Full text Link to item Cite

Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019.

Journal Article Lancet · October 17, 2020 BACKGROUND: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. Th ... Full text Link to item Cite

Association of Sedentary Behavior With Cancer Mortality in Middle-aged and Older US Adults.

Journal Article JAMA Oncol · August 1, 2020 IMPORTANCE: Sedentary behavior is associated with several health outcomes, including diabetes, cardiovascular disease, and all-cause mortality. Less is known about the association between objectively measured sedentary behavior and cancer mortality, as wel ... Full text Link to item Cite

Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017.

Journal Article Nat Med · August 2020 An amendment to this paper has been published and can be accessed via a link at the top of the paper. ... Full text Open Access Link to item Cite

Mediating Effects of Frailty Indicators on the Risk of Sepsis After Cancer.

Journal Article J Intensive Care Med · July 2020 BACKGROUND: Cancer survivors are at increased risk of sepsis, possibly attributed to weakened physiologic conditions. The aims of this study were to examine the mediation effect of indicators of frailty on the association between cancer survivorship and se ... Full text Link to item Cite

Association of Allostatic Load with All-Cause andCancer Mortality by Race and Body Mass Index in theREGARDS Cohort.

Journal Article Cancers (Basel) · June 26, 2020 Among 29,701 Black and White participants aged 45 years and older in the Reasons forGeographic and Racial Difference in Stroke (REGARDS) study, allostatic load (AL) was defined asthe sum score of established baseline risk-associated biomarkers for which pa ... Full text Link to item Cite

The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet Gastroenterol Hepatol · June 2020 BACKGROUND: Oesophageal cancer is a common and often fatal cancer that has two main histological subtypes: oesophageal squamous cell carcinoma and oesophageal adenocarcinoma. Updated statistics on the incidence and mortality of oesophageal cancer, and on t ... Full text Link to item Cite

Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017.

Journal Article Nat Med · May 2020 A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- ... Full text Open Access Link to item Cite

Mobile Technologies and Cervical Cancer Screening in Low- and Middle-Income Countries: A Systematic Review.

Journal Article JCO Glob Oncol · April 2020 PURPOSE: Cervical cancer screening is not well implemented in many low- and middle-income countries (LMICs). Mobile health (mHealth) refers to utilization of mobile technologies in health promotion and disease management. We aimed to qualitatively synthesi ... Full text Link to item Cite

The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet Gastroenterol Hepatol · March 2020 BACKGROUND: Cirrhosis and other chronic liver diseases (collectively referred to as cirrhosis in this paper) are a major cause of morbidity and mortality globally, although the burden and underlying causes differ across locations and demographic groups. We ... Full text Link to item Cite

Global and regional burden of disease and injury in 2016 arising from occupational exposures: a systematic analysis for the Global Burden of Disease Study 2016.

Journal Article Occup Environ Med · March 2020 OBJECTIVES: This study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study. METHODS: The GBD 2016 study estimated the ... Full text Open Access Link to item Cite

Global and regional burden of cancer in 2016 arising from occupational exposure to selected carcinogens: a systematic analysis for the Global Burden of Disease Study 2016.

Journal Article Occup Environ Med · March 2020 OBJECTIVES: This study provides a detailed analysis of the global and regional burden of cancer due to occupational carcinogens from the Global Burden of Disease 2016 study. METHODS: The burden of cancer due to 14 International Agency for Research on Cance ... Full text Open Access Link to item Cite

Correction: Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort.

Journal Article Oncotarget · February 18, 2020 [This corrects the article DOI: 10.18632/oncotarget.27108.]. ... Full text Link to item Cite

Erratum: Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort (Oncotarget (2019) 10 (4857-4867) DOI: 10.18632/oncotarget.27108)

Journal Article Oncotarget · February 18, 2020 This article has been corrected: The third author in the listing, along with a new affiliation, has been added as follows: Daniel Tefera Dibaba3 3Tennessee Clinical and Translational Science Institute, University of Tennessee Health Science Center, Memphis ... Cite

The global, regional, and national burden of stomach cancer in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease study 2017.

Journal Article Lancet Gastroenterol Hepatol · January 2020 BACKGROUND: Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach cancer and the differential trends across various locations is essential for formulating effective preventive strategies. We report on the i ... Full text Link to item Cite

Mapping disparities in education across low- and middle-income countries.

Journal Article Nature · January 2020 Educational attainment is an important social determinant of maternal, newborn, and child health1-3. As a tool for promoting gender equity, it has gained increasing traction in popular media, international aid strategies, and global agenda-setting4-6. The ... Full text Open Access Link to item Cite

Variants in SNAI1, AMDHD1 and CUBN in vitamin D pathway genes are associated with breast cancer risk: a large-scale analysis of 14 GWASs in the DRIVE study.

Journal Article Am J Cancer Res · 2020 Vitamin D has a potential anticarcinogenic role, possibly through regulation of cell proliferation and differentiation, stimulation of apoptosis, immune modulation and regulation of estrogen receptor levels. Because breast cancer (BC) risk varies among ind ... Open Access Link to item Cite

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study.

Journal Article JAMA Oncol · December 1, 2019 IMPORTANCE: Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the ... Full text Link to item Cite

Hospitalization outcomes and racial disparities in cervical cancer patients: An analysis of the national inpatient sample data from 2002 to 2014.

Journal Article Cancer Epidemiol · December 2019 BACKGROUND: Little is known about outcomes in patients after being hospitalized for care of cancer or comorbid conditions and the disparity between African-American and White cervical cancer patients. METHODS: Using the national inpatient sample (HCUP-NIS) ... Full text Link to item Cite

The global, regional, and national burden of pancreatic cancer and its attributable risk factors in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet Gastroenterol Hepatol · December 2019 BACKGROUND: Worldwide, both the incidence and death rates of pancreatic cancer are increasing. Evaluation of pancreatic cancer burden and its global, regional, and national patterns is crucial to policy making and better resource allocation for controlling ... Full text Link to item Cite

The global, regional, and national burden of colorectal cancer and its attributable risk factors in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet Gastroenterol Hepatol · December 2019 BACKGROUND: Data about the global, regional, and country-specific variations in the levels and trends of colorectal cancer are required to understand the impact of this disease and the trends in its burden to help policy makers allocate resources. Here we ... Full text Link to item Cite

Race, Socioeconomic Status, and Health-Care Access Disparities in Ovarian Cancer Treatment and Mortality: Systematic Review and Meta-Analysis.

Journal Article JNCI Cancer Spectr · December 2019 BACKGROUND: Ovarian cancer remains a leading cause of death from gynecological malignancies. Race, socioeconomic status (SES), and access to health care are important predictors of quality treatment and survival. We provide a systematic review and meta-ana ... Full text Link to item Cite

Current smoking and quit-attempts among US adults following Medicaid expansion.

Journal Article Prev Med Rep · September 2019 The objective of this study was to estimate the influence of the Affordable Care Act (ACA) Medicaid Expansion on current smoking and quit attempts in expanded and non-expanded states. We analyzed data from the Behavioral Risk Factor Surveillance System (BR ... Full text Link to item Cite

Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort.

Journal Article Oncotarget · August 6, 2019 This study examines the association between inflammatory biomarkers and risk of cancer mortality by race. Data were obtained from 1,856 participants in the prospective REGARDS cohort who were cancer-free at baseline, and analyzed in relation to cancer mort ... Full text Link to item Cite

Department of Error.

Journal Article Lancet · June 22, 2019 Full text Link to item Cite

Collaborative Molecular Epidemiology Study of Metabolic Dysregulation, DNA Methylation, and Breast Cancer Risk Among Nigerian Women: MEND Study Objectives and Design.

Journal Article J Glob Oncol · June 2019 PURPOSE: To elucidate the role of metabolic dysregulation and associated DNA methylation changes on breast cancer risk and aggressive subtypes among Nigerian women. We describe the design and methods of a collaborative molecular epidemiology study of breas ... Full text Link to item Cite

Health effects of dietary risks in 195 countries, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · May 11, 2019 BACKGROUND: Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate the consumption of major foods and nutri ... Full text Link to item Cite

Association between obesity and biomarkers of inflammation and metabolism with cancer mortality in a prospective cohort study.

Journal Article Metabolism · May 2019 OBJECTIVE: To investigate the association between biomarkers of inflammation and metabolic dysregulation and cancer mortality by obesity status. METHODS: Data from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort was used to exa ... Full text Link to item Cite

Chronic inflammation and risk of lung cancer in older adults in the health, aging and body composition cohort study.

Journal Article J Geriatr Oncol · March 2019 OBJECTIVES: We examined the association between three inflammatory markers (Interleukin (IL)-6, C-reactive protein (CRP), tumor necrosis factor (TNF)-α) and incident lung cancer using baseline, updated, and averaged inflammatory measures in older adults. M ... Full text Link to item Cite

Targeting risk factors for reducing the racially disparate burden in breast cancer.

Journal Article Front Biosci (Schol Ed) · March 1, 2019 African-American (AA) women are more likely to die from breast cancer (BC), at any age, compared to European-American women. Although breakthroughs in pre-clinical studies have resulted in potentially actionable targets in AA BC, drugs that were rationally ... Full text Link to item Cite

Metabolic syndrome and risk of breast cancer mortality by menopause, obesity, and subtype.

Journal Article Breast Cancer Res Treat · February 2019 PURPOSE: To investigate the association between metabolic syndrome (MetS) and risk of breast cancer mortality by menopausal status, obesity, and subtype. METHODS: Data from 94,555 women free of cancer at baseline in the National Institute of Health-America ... Full text Link to item Cite

Medicaid Expansion and Breast Cancer Screening in Appalachia and Non-Appalachia, United States, BRFSS 2003 to 2015.

Journal Article Cancer Control · 2019 BACKGROUND: Prior data suggests that breast cancer screening rates are lower among women in the Appalachian region of the United States. This study examined the changes in breast cancer screening before and after the implementation of the Affordable Care A ... Full text Link to item Cite

Association between life-course socio-economic status and prevalence of cardio-metabolic risk ractors in five middle-income countries.

Journal Article J Glob Health · December 2018 BACKGROUND: The burden of non-communicable diseases has increased rapidly in low- and middle-income countries. Past studies have reported an association between socioeconomic status (SES) and cardio-metabolic risk factors, but most have focused on upper in ... Full text Link to item Cite

Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk-outcome ... Full text Open Access Link to item Cite

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 20 ... Full text Open Access Link to item Cite

Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global B ... Full text Open Access Link to item Cite

Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates of population and fertility, alth ... Full text Open Access Link to item Cite

Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no on ... Full text Open Access Link to item Cite

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

Journal Article Lancet · November 10, 2018 BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We c ... Full text Open Access Link to item Cite

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016: A Systematic Analysis for the Global Burden of Disease Study.

Journal Article JAMA Oncol · November 1, 2018 IMPORTANCE: The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organizati ... Full text Link to item Cite

Alcohol use and burden for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

Journal Article Lancet · September 22, 2018 BACKGROUND: Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to ... Full text Link to item Cite

Metabolic Syndrome and the Risk of Breast Cancer and Subtypes by Race, Menopause and BMI.

Journal Article Cancers (Basel) · September 1, 2018 The objective of this study was to investigate the association of metabolic syndrome (MetS) with the risk of invasive breast cancer and molecular subtypes across race, menopause, and body mass index (BMI) groups. We examined the association of metabolic sy ... Full text Link to item Cite

The association of early life socioeconomic position on breast cancer incidence and mortality: a systematic review.

Journal Article Int J Public Health · September 2018 OBJECTIVES: We conducted a systematic review of the literature relating early life socioeconomic position (SEP) to breast cancer incidence and mortality from a critical period and life-course trajectory perspective. METHODS: PubMed, EMBASE and Web of Scien ... Full text Link to item Cite

A prospective study of cancer survivors and risk of sepsis within the REGARDS cohort.

Journal Article Cancer Epidemiol · August 2018 BACKGROUND: Hospitalized cancer patients are nearly 10 times more likely to develop sepsis when compared to patients with no cancer history. We compared the risk of sepsis between cancer survivors and no cancer history participants, and examined whether ra ... Full text Link to item Cite

Mapping hot spots of breast cancer mortality in the United States: place matters for Blacks and Hispanics.

Journal Article Cancer Causes Control · August 2018 PURPOSE: The goals of this study were to identify geographic and racial/ethnic variation in breast cancer mortality, and evaluate whether observed geographic differences are explained by county-level characteristics. METHODS: We analyzed data on breast can ... Full text Link to item Cite

Abstract 3229: Prediagnostic biomarkers of metabolic dysregulation and cancer mortality

Conference Cancer Research · July 1, 2018 AbstractINTRODUCTION: The obesogenic milieu is a pro-tumorigenic environment that promotes tumor initiation, angiogenesis and metastasis. In this prospective cohort, we examined the association between pre-d ... Full text Cite

Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016.

Journal Article Lancet · June 2, 2018 BACKGROUND: A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries is crucial to guiding decisions ... Full text Link to item Cite

Sleep disorder diagnoses and clinical outcomes among hospitalized breast cancer patients: a nationwide inpatient sample study.

Journal Article Support Care Cancer · June 2018 PURPOSE: Sleep disturbances are recognized as a problem for many cancer patients, but little is known about the prevalence of sleep disorders among women hospitalized with breast cancer, or their relationship to in-hospital outcomes. The present study repr ... Full text Link to item Cite

The State of US Health, 1990-2016: Burden of Diseases, Injuries, and Risk Factors Among US States.

Journal Article JAMA · April 10, 2018 INTRODUCTION: Several studies have measured health outcomes in the United States, but none have provided a comprehensive assessment of patterns of health by state. OBJECTIVE: To use the results of the Global Burden of Disease Study (GBD) to report trends i ... Full text Link to item Cite

Racial/ethnic disparities in de novo metastases sites and survival outcomes for patients with primary breast, colorectal, and prostate cancer.

Journal Article Cancer Med · April 2018 Racial disparities in cancer mortality still exist despite improvements in treatment strategies leading to improved survival for many cancer types. In this study, we described race/ethnic differences in patterns of de novo metastasis and evaluated the asso ... Full text Link to item Cite

Pre-diagnostic biomarkers of metabolic dysregulation and cancer mortality.

Journal Article Oncotarget · March 23, 2018 INTRODUCTION: The obesogenic milieu is a pro-tumorigenic environment that promotes tumor initiation, angiogenesis and metastasis. In this prospective cohort, we examined the association between pre-diagnostic metabolic biomarkers, plasma adiponectin, resis ... Full text Link to item Cite

In-Hospital Mortality and Post-Surgical Complications Among Cancer Patients with Metabolic Syndrome.

Journal Article Obes Surg · March 2018 BACKGROUND: Metabolic syndrome (MetS) is an important etiologic and prognostic factor for cancer, but few studies have assessed hospitalization outcomes among patients with both conditions. METHODS: Data was obtained from the Healthcare Cost and Utilizatio ... Full text Link to item Cite

Demographic, presentation, and treatment factors and racial disparities in ovarian cancer hospitalization outcomes.

Journal Article Cancer Causes Control · March 2018 BACKGROUND: This study examines whether racial disparities in hospitalization outcomes persist between African-American and White women with ovarian cancer after matching on demographic, presentation, and treatment factors. METHODS: Using data from the Nat ... Full text Link to item Cite

A Prospective Study of Obesity, Metabolic Health, and Cancer Mortality.

Journal Article Obesity (Silver Spring) · January 2018 OBJECTIVE: This study examined whether metabolic health status is associated with risk of cancer mortality and whether this varies by body mass index (BMI) category. METHODS: A prospective study of 22,514 participants from the Reasons for Geographic and Ra ... Full text Link to item Cite

Screening mammography use in older women according to health status: a systematic review and meta-analysis.

Journal Article Clin Interv Aging · 2018 BACKGROUND: The extent to which screening mammography (SM) recommendations in older women incorporate life expectancy factors is not well established. OBJECTIVE: The objective of this review was to evaluate evidence on SM utilization in older women by life ... Full text Link to item Cite

Epigenome-wide association study of metabolic syndrome in African-American adults.

Journal Article Clin Epigenetics · 2018 BACKGROUND: The high prevalence of obesity among US adults has resulted in significant increases in associated metabolic disorders such as diabetes, dyslipidemia, and high blood pressure. Together, these disorders constitute metabolic syndrome, a clinicall ... Full text Link to item Cite

Mediating effects of cancer risk factors on the association between race and cancer incidence: analysis of the NIH-AARP Diet and Health Study.

Journal Article Ann Epidemiol · January 2018 PURPOSE: Racial disparities exist in the prevalence of cancer-related risk factors and incidence of cancer. The objective of this study is to determine if cancer-related risk factors mediate the association between race and cancer incidence. METHODS: We pe ... Full text Link to item Cite

Metabolic dysregulation and cancer mortality in a national cohort of blacks and whites.

Journal Article BMC Cancer · December 15, 2017 BACKGROUND: We examined the association between metabolic dysregulation and cancer mortality in a prospective cohort of Black and White adults. METHODS: A total of 25,038 Black and White adults were included in the analysis. Metabolic dysregulation was def ... Full text Link to item Cite

Meta-analysis of the association between dietary inflammatory index (DII) and cancer outcomes.

Journal Article Int J Cancer · December 1, 2017 Proinflammatory dietary patterns have been associated with increased cancer risk and mortality. We present a systematic review and meta-analysis of the current published literature on a dietary inflammatory index (DII) score and its association with cancer ... Full text Link to item Cite

The Burden of Primary Liver Cancer and Underlying Etiologies From 1990 to 2015 at the Global, Regional, and National Level: Results From the Global Burden of Disease Study 2015.

Journal Article JAMA Oncol · December 1, 2017 IMPORTANCE: Liver cancer is among the leading causes of cancer deaths globally. The most common causes for liver cancer include hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and alcohol use. OBJECTIVE: To report results of the Global Burden ... Full text Link to item Cite

Metabolic syndrome and in-hospital outcomes among pancreatic cancer patients.

Journal Article Diabetes Metab Syndr · December 2017 AIMS: Metabolic Syndrome (MetS) is an important etiologic and prognostic factor for pancreatic cancer, but few studies have assessed health outcomes among hospitalized pancreatic cancer patients. We examined the associations between MetS and in-hospital ou ... Full text Link to item Cite

Global, regional, and national under-5 mortality, adult mortality, age-specific mortality, and life expectancy, 1970-2016: a systematic analysis for the Global Burden of Disease Study 2016.

Journal Article Lancet · September 16, 2017 BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respe ... Full text Link to item Cite

Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016.

Journal Article Lancet · September 16, 2017 BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and pro ... Full text Link to item Cite

Trends in smoking and obesity among US adults before, during, and after the great recession and Affordable Care Act roll-out.

Journal Article Prev Med · September 2017 This study examined trends in smoking and overweight/obesity rates among United States (US) adults ages 40years and older by race and socio-economic status (SES) across three study periods; pre-recession (2003-2005), recession (2007-2009), and post-recessi ... Full text Link to item Cite

Trends in breast and colorectal cancer screening among U.S. adults by race, healthcare coverage, and SES before, during, and after the great recession.

Journal Article Prev Med Rep · September 2017 The aim of this study is examine trends in breast and colorectal cancer screening in the U.S. by race, healthcare coverage, and socio-economic status (SES) before the Great Recession (2003-2005), during the recession (2007-2009), and post-recession/Afforda ... Full text Link to item Cite

Cancer-related risk factors and incidence of major cancers by race, gender and region; analysis of the NIH-AARP diet and health study.

Journal Article BMC Cancer · August 30, 2017 BACKGROUND: Racial disparities in the incidence of major cancers may be attributed to differences in the prevalence of established, modifiable risk factors such as obesity, smoking, physical activity and diet. METHODS: Data from a prospective cohort of 566 ... Full text Link to item Cite

Availability of healthcare resources and epithelial ovarian cancer stage of diagnosis and mortality among Blacks and Whites.

Journal Article J Ovarian Res · August 22, 2017 BACKGROUND: The purpose of this study is to examine whether racial disparities in epithelial ovarian cancer stage at diagnosis and survival may be explained by geographic availability of healthcare resources among Blacks and Whites. METHODS: Data from the ... Full text Link to item Cite

Sequential matched analysis of racial disparities in breast cancer hospitalization outcomes among African American and White patients.

Journal Article Cancer Epidemiol · August 2017 BACKGROUND: The purpose of this study is to determine if racial disparities in inpatient outcomes persist among hospitalized patients comparing African American and White breast cancer patients matched on demographics, presentation and treatment. METHODS: ... Full text Link to item Cite

Pollution and regional variations of lung cancer mortality in the United States.

Journal Article Cancer Epidemiol · August 2017 INTRODUCTION: The aims of this study were to identify counties in the United States (US) with high rates of lung cancer mortality, and to characterize the associated community-level factors while focusing on particulate-matter pollution. METHODS: We perfor ... Full text Link to item Cite

Healthcare Access and Quality Index based on mortality from causes amenable to personal health care in 195 countries and territories, 1990-2015: a novel analysis from the Global Burden of Disease Study 2015.

Journal Article Lancet · July 15, 2017 BACKGROUND: National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality ... Full text Link to item Cite

Abstract 4243: Epigenome-wide association study of metabolic syndrome in African-Americans

Conference Cancer Research · July 1, 2017 AbstractBackground: The epidemic of obesity among US adults has resulted in significant increases in associated metabolic disorders such as diabetes, dyslipidemia and high blood pressure. Together, these dis ... Full text Cite

Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988-2012.

Journal Article Prev Chronic Dis · March 16, 2017 INTRODUCTION: Metabolic syndrome is a cluster of cardiometabolic risk factors associated with increased risk of multiple chronic diseases, including cancer and cardiovascular disease. The objectives of this study were to estimate the prevalence of metaboli ... Full text Link to item Cite

HYPERTHYROIDISM INCREASES THE RISK OF TAKOTSUBO CARDIOMYOPATHY AMONG HOSPITALIZED U.S. PATIENTS

Conference Journal of the American College of Cardiology · March 2017 Full text Cite

Screening, prevalence, and risk factors for cervical lesions among HIV positive and HIV negative women in Swaziland.

Journal Article BMC Public Health · February 21, 2017 BACKGROUND: Cervical Cancer (CC) is the number one cancer among women in sub-Saharan Africa. Although CC is preventable, most women in developing countries do not have access to screening. METHODS: This cross-sectional study was conducted to determine the ... Full text Link to item Cite

Lifecourse socioeconomic status and cancer-related risk factors: Analysis of the WHO study on global ageing and adult health (SAGE).

Journal Article Int J Cancer · February 15, 2017 Few studies have examined cancer-related risk factors in relation to SES across the lifecourse in low to middle income countries. This analysis focuses on adult women in India, China, Mexico, Russia and South Africa, and examines the association between in ... Full text Link to item Cite

Disparities in hospitalization outcomes among African-American and White prostate cancer patients.

Journal Article Cancer Epidemiol · February 2017 OBJECTIVES: This paper aims to determine whether racial disparities exist in hospitalization outcomes among African-American and White hospitalized prostate cancer patients in the United States. We evaluated racial differences among matched groups of patie ... Full text Link to item Cite

Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015.

Journal Article JAMA · January 10, 2017 IMPORTANCE: Elevated systolic blood (SBP) pressure is a leading global health risk. Quantifying the levels of SBP is important to guide prevention policies and interventions. OBJECTIVE: To estimate the association between SBP of at least 110 to 115 mm Hg a ... Full text Link to item Cite

Department of Error.

Journal Article Lancet · January 7, 2017 Full text Link to item Cite

Department of Error.

Journal Article Lancet · January 7, 2017 Full text Link to item Cite

Diabetes Mellitus with Chronic Complications in Relation to Carotid Endarterectomy and Carotid Artery Stenting Outcomes.

Journal Article J Stroke Cerebrovasc Dis · January 2017 BACKGROUND: Carotid endarterectomy and carotid artery stenting are effective treatment procedures for carotid artery stenosis. Although diabetes mellitus is highly prevalent among patients undergoing these revascularization procedures, few studies have exa ... Full text Link to item Cite

Socioeconomic Disparities in the Prevalence of Cardiometabolic Risk Factors in Ghanaian Women.

Journal Article Ann Glob Health · 2017 BACKGROUND: Recent trends toward urbanization in developing countries like Ghana, coupled with nutritional transition and aging populations, have led to a rapid increase in the prevalence of noncommunicable diseases such as obesity, diabetes, and hypertens ... Full text Link to item Cite

Marijuana use and inpatient outcomes among hospitalized patients: analysis of the nationwide inpatient sample database.

Journal Article Cancer Med · January 2017 The purpose of this paper is to examine the relationship between marijuana use and health outcomes among hospitalized patients, including those hospitalized with a diagnosis of cancer. A total of 387,608 current marijuana users were identified based on ICD ... Full text Link to item Cite

Pathway-Structured Predictive Model for Cancer Survival Prediction: A Two-Stage Approach.

Journal Article Genetics · January 2017 Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer patients has been a persistent problem for many decades. Currently, prognosis and outcome predictions are made based on clinical factors and/or by incorporating molecular ... Full text Link to item Cite

Socio-economic status over the life course and obesity: Systematic review and meta-analysis.

Journal Article PLoS One · 2017 BACKGROUND: The purpose of this review was to summarize the published literature on the association of childhood, adulthood and life course socio-economic status (SES) with obesity between January 1990 and June 2015. METHODS: The major medical electronic d ... Full text Link to item Cite

Epidemiology of Chikungunya fever outbreak in Western Jamaica during July-December 2014

Journal Article Res Rep Trop Med · 2017 Objective: Our study describes the 2014 Chikungunya outbreak in Western Jamaica in terms of geographic distribution and trend of the outbreak over time, and evaluates clinical symptoms of the disease based on pre-existing conditions. Methods: We conducted ... Full text Cite

Epigenetic Biomarkers in Cancer Epidemiology

Chapter · January 1, 2017 Cancer remains a significant global public health issue, with 17.5 million incident cancer cases and 8.7 million cancer deaths in 2015. Although traditional epidemiology methods have significantly improved understanding of etiologic and prognostic risk fac ... Full text Cite

Life-course socioeconomic status and breast and cervical cancer screening: analysis of the WHO's Study on Global Ageing and Adult Health (SAGE).

Journal Article BMJ Open · November 22, 2016 OBJECTIVES: Socioeconomic differences in screening have been well documented in upper-income countries; however, few studies have examined socioeconomic status (SES) over the life-course in relation to cancer screening in lower-income and middle-income cou ... Full text Link to item Cite

A prospective study of dietary patterns and cancer mortality among Blacks and Whites in the REGARDS cohort.

Journal Article Int J Cancer · November 15, 2016 Marked racial differences exist in dietary patterns and obesity, as well as cancer mortality. This study aims to assess whether dietary patterns are associated with cancer mortality overall and by race. We identified 22,041 participants from the REasons fo ... Full text Link to item Cite

Life-course socio-economic status and adult BMI in Ghana; analysis of the WHO study on global ageing and adult health (SAGE).

Journal Article Int J Equity Health · November 15, 2016 BACKGROUND: Obesity rates have continued to increase over time globally, resulting in an increase in the burden of obesity-associated chronic diseases. There is a paucity of research on the association between obesity and generational changes in socio-econ ... Full text Link to item Cite

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.

Journal Article Lancet · October 8, 2016 BACKGROUND: Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-caus ... Full text Link to item Cite

Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015.

Journal Article Lancet · October 8, 2016 BACKGROUND: In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 health-related SDG indicator ... Full text Link to item Cite

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

Journal Article Lancet · October 8, 2016 BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning th ... Full text Link to item Cite

Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.

Journal Article Lancet · October 8, 2016 BACKGROUND: Established in 2000, Millennium Development Goal 4 (MDG4) catalysed extraordinary political, financial, and social commitments to reduce under-5 mortality by two-thirds between 1990 and 2015. At the country level, the pace of progress in improv ... Full text Link to item Cite

Global, regional, and national levels of maternal mortality, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

Journal Article Lancet · October 8, 2016 BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame ... Full text Link to item Cite

Race/ethnicity and socio-economic differences in colorectal cancer surgery outcomes: analysis of the nationwide inpatient sample.

Journal Article BMC Cancer · September 5, 2016 BACKGROUND: The purpose of this study was to examine racial and socio-economic differences in the receipt of laparoscopic or open surgery among patients with colorectal cancer, and to determine if racial and socio-economic differences exist in post-surgica ... Full text Link to item Cite

Erratum: Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: The Global Burden of Disease Study 2015 (The Lancet HIV (2016) 3 (e361-e387) PII: S235230181630087X DOI: 10.1016/S2352-3018(16)30087-X)

Journal Article The Lancet HIV · September 1, 2016 GBD 2015 HIV Collaborators. Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015. Lancet HIV 2016; 3: e361–87—In this Article, Kerrie E Doyle and David M Pereira have be ... Full text Cite

Data on burden of comorbidities in the united states and medicaid expansion status.

Journal Article Data Brief · September 2016 The high prevalence of comorbidities among US adults is a major public health problem. However, there is limited data on the geographic distribution of comorbidities. In addition, recent changes to health insurance programs in the US through the Affordable ... Full text Link to item Cite

A two-stage approach for combining gene expression and mutation with clinical data improves survival prediction in myelodysplastic syndromes and ovarian cancer.

Journal Article J Bioinform Genom · September 2016 MOTIVATION: Many traditional clinical prognostic factors have been known for cancer for years, but usually provide poor survival prediction. Genomic information is more easily available now which offers opportunities to build more accurate prognostic model ... Full text Link to item Cite

Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980-2015: the Global Burden of Disease Study 2015.

Journal Article Lancet HIV · August 2016 BACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS inciden ... Full text Link to item Cite

Racial and socio-economic disparities in breast cancer hospitalization outcomes by insurance status.

Journal Article Cancer Epidemiol · August 2016 BACKGROUND: Breast cancer remains a major cause of morbidity and mortality among women in the US, and despite numerous studies documenting racial disparities in outcomes, the survival difference between Black and White women diagnosed with breast cancer co ... Full text Link to item Cite

Early life growth, socioeconomic status, and mammographic breast density in an urban US birth cohort.

Journal Article Ann Epidemiol · August 2016 PURPOSE: Rapid infant and childhood growth has been associated with chronic disease later in life, including breast cancer. Early life socioeconomic status (SES) influences childhood growth, but few studies have prospective measures from birth to consider ... Full text Link to item Cite

Abstract 1771: Metabolic dysregulation and cancer mortality in a national cohort of African-Americans and whites

Conference Cancer Research · July 15, 2016 AbstractIntroduction: Complex biological pathways link metabolic dysregulation (obesity, hypertension, dyslipidemia and diabetes) with cancer tumorigenesis, progression and metastasis, and those include high ... Full text Cite

Disparities in the prevalence of comorbidities among US adults by state Medicaid expansion status.

Journal Article Prev Med · July 2016 INTRODUCTION: About 92% of US older adults have at least one chronic disease or medical condition and 77% have at least two. Low-income and uninsured adults in particular experience a higher burden of comorbidities, and the Medicaid expansion provision of ... Full text Link to item Cite

Association between body mass index and in-hospital outcomes: Analysis of the nationwide inpatient database.

Journal Article Medicine (Baltimore) · July 2016 IMPORTANCE: Over one-third of American adults (36%) are obese and more than two-thirds (69%) are overweight. The impact of obesity on hospitalization outcomes is not well understood. OBJECTIVE: To examine the association between body mass index (BMI) and o ... Full text Link to item Cite

Racial disparities in individual breast cancer outcomes by hormone-receptor subtype, area-level socio-economic status and healthcare resources.

Journal Article Breast Cancer Res Treat · June 2016 The aim of the study is to determine the influence of area-level socio-economic status and healthcare access in addition to tumor hormone-receptor subtype on individual breast cancer stage, treatment, and mortality among Non-Hispanic (NH)-Black, NH-White, ... Full text Link to item Cite

Adherence to cancer prevention guidelines in South Africa is associated with health care access.

Journal Article Int Health · May 2016 BACKGROUND: Cancer prevention guidelines have been developed to improve knowledge and adherence to modifiable cancer risk factors. The implementation of these guidelines has largely been studied in North American and European populations. The aim of this s ... Full text Link to item Cite

Availability of Healthcare Resources and Colorectal Cancer Outcomes Among Non-Hispanic White and Non-Hispanic Black Adults.

Journal Article J Community Health · April 2016 This study aims to examine if access to healthcare, measured through the availability of medical resources at the neighborhood level, influences colorectal cancer (CRC) stage, treatment and survival using the Surveillance Epidemiology and Ends Result (SEER ... Full text Link to item Cite

Temporal Variation and Association of Aflatoxin B₁ Albumin-Adduct Levels with Socio-Economic and Food Consumption Factors in HIV Positive Adults.

Journal Article Toxins (Basel) · November 30, 2015 The association between aflatoxin exposure and alteration in immune responses observed in humans suggest that aflatoxin could suppress the immune system and work synergistically with HIV to increase disease severity and progression to AIDS. No longitudinal ... Full text Link to item Cite

Race/ethnicity and socio-economic differences in breast cancer surgery outcomes.

Journal Article Cancer Epidemiol · October 2015 BACKGROUND: The purpose of this study is to evaluate racial and socio-economic differences in breast cancer surgery treatment, post-surgical complications, hospital length of stay and mortality among hospitalized breast cancer patients. METHODS: We examine ... Full text Link to item Cite

Breast cancer survival in African-American women by hormone receptor subtypes.

Journal Article Breast Cancer Res Treat · August 2015 Breast cancer accounts for over 200,000 annual cases among women in the United States, and is the second leading cause of cancer-related deaths. However, few studies have investigated the association between breast cancer subtype and survival among African ... Full text Link to item Cite

Health care access dimensions and cervical cancer screening in South Africa: analysis of the world health survey.

Journal Article BMC Public Health · April 15, 2015 BACKGROUND: Cervical cancer is the most commonly diagnosed cancer and the leading cause of cancer mortality among women in sub-Saharan Africa. Recent recommendations for cervical cancer primary prevention highlight HPV vaccination, and secondary prevention ... Full text Link to item Cite

Acculturation and Ethnic Variations in Breast Cancer Risk Factors, Gail Model Risk Estimates and Mammographic Breast Density

Conference Cancer Epidemiology, Biomarkers & Prevention · April 1, 2015 AbstractBreast cancer (BC) incidence varies across countries and across US ethnic groups. US Immigrants often exhibit an intermediate level of risk between those observed in their birth country and in the US ... Full text Cite

Residential environment and breast cancer incidence and mortality: a systematic review and meta-analysis.

Journal Article BMC Cancer · March 28, 2015 BACKGROUND: Factors beyond the individual level such as those characterizing the residential environment may be important to breast cancer outcomes. We provide a systematic review and results of meta-analysis of the published empirical literature on the as ... Full text Link to item Cite

Socioeconomic status and incidence of breast cancer by hormone receptor subtype

Journal Article Springerplus · 2015 Recent developments in genetics and molecular biology have classified breast cancer into subtypes based on tumor markers of estrogen (ER), progesterone (PR) and human epidermal growth Factor-2 receptors (Her-2), with the basal-like (ER-, PR-, Her2-) subtyp ... Full text Cite

Depression and Anxiety Disorders among Hospitalized Women with Breast Cancer.

Journal Article PLoS One · 2015 PURPOSE: To document the prevalence of depression and anxiety disorders, and their associations with mortality among hospitalized breast cancer patients. METHODS: We examined the associations between breast cancer diagnosis and the diagnoses of anxiety or ... Full text Link to item Cite

Adherence to cancer prevention guidelines in 18 African countries.

Journal Article PLoS One · 2014 BACKGROUND: Cancer rates in Africa are projected to double by 2030 due to aging and increased exposure to cancer risk factors, including modifiable risk factors. We assessed adherence to 5 modifiable cancer risk factors across 18 African countries. METHODS ... Full text Link to item Cite

Trends in breast cancer stage and mortality in Michigan (1992-2009) by race, socioeconomic status, and area healthcare resources.

Journal Article PLoS One · 2013 The long-term effect of socioeconomic status (SES) and healthcare resources availability (HCA) on breast cancer stage of presentation and mortality rates among patients in Michigan is unclear. Using data from the Michigan Department of Community Health (MD ... Full text Link to item Cite

Individual and neighborhood socioeconomic status and healthcare resources in relation to black-white breast cancer survival disparities

Journal Article J Cancer Epidemiol · 2013 Background. Breast cancer survival has improved significantly in the US in the past 10-15 years. However, disparities exist in breast cancer survival between black and white women. Purpose. To investigate the effect of county healthcare resources and SES a ... Full text Cite

Healthcare access and mammography screening in Michigan: a multilevel cross-sectional study.

Journal Article Int J Equity Health · March 21, 2012 BACKGROUND: Breast cancer screening rates have increased over time in the United States. However actual screening rates appear to be lower among black women compared with white women. PURPOSE: To assess determinants of breast cancer screening among women i ... Full text Link to item Cite

Socio-economic and health access determinants of breast and cervical cancer screening in low-income countries: analysis of the World Health Survey.

Journal Article PLoS One · 2012 BACKGROUND: Breast and Cervical cancer are the two most common cancers among women in developing countries. Regular screening is the most effective way of ensuring that these cancers are detected at early stages; however few studies have assessed factors t ... Full text Link to item Cite