Journal ArticleGynecol Oncol · August 29, 2024
OBJECTIVE: Ovarian cancer has poor 5-year survival, particularly among non-Hispanic (NH) Black patients. Efforts to identify patients at high-risk of functional limitations and frailty may improve outcomes. In this study, we examined how healthcare access ...
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Journal ArticleCancer Epidemiol · August 1, 2024
We characterized trends in early onset (aged 20-49) cancer incidence by race/ethnicity and sex using the 2011-2020 Surveillance, Epidemiology, and End Results (SEER) Program dataset. We estimated age-standardized cancer incidence rates, incidence rate rati ...
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Journal ArticleJ Environ Radioact · July 2024
Radon is a naturally occurring radioactive gas that poses significant health risks to humans, including increased risk of lung cancer. This study investigates the association of neighborhood-level socioeconomic variables with radon testing and radon exposu ...
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Journal ArticleJ Natl Cancer Inst · June 7, 2024
BACKGROUND: Racial and ethnic disparities in genomic testing could exacerbate disparities in access to precision cancer therapies and survival-particularly in the context of lung cancer where genomic testing has been recommended for the past decade. Howeve ...
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Journal ArticleCancer Epidemiol Biomarkers Prev · June 3, 2024
BACKGROUND: The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer population and examine AI-White dis ...
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Other · June 3, 2024
<p>Supplemental Table S1: Clinical and sociodemographic characteristics of Non-Hispanic American Indian in PRCDA counties and Non-Hispanic White cancer cases diagnosed between 2014-2018 (n=206,774)</p> ...
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Other · June 3, 2024
<p>Supplemental Table S2: Comparison of clinical and sociodemographic characteristics across American Indian classifications for persons diagnosed with cancer between 2014-2018</p> ...
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Other · June 3, 2024
<div>AbstractBackground:<p>The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer ...
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Other · June 3, 2024
<div>AbstractBackground:<p>The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer ...
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Other · June 3, 2024
<p>Supplemental Figure S1: Standardized incidence estimates per 100k across classifications of American Indian persons</p> ...
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Other · June 3, 2024
<p>Supplemental Table S2: Comparison of clinical and sociodemographic characteristics across American Indian classifications for persons diagnosed with cancer between 2014-2018</p> ...
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Other · June 3, 2024
<p>Supplemental Figure S1: Standardized incidence estimates per 100k across classifications of American Indian persons</p> ...
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Other · June 3, 2024
<p>Supplemental Table S1: Clinical and sociodemographic characteristics of Non-Hispanic American Indian in PRCDA counties and Non-Hispanic White cancer cases diagnosed between 2014-2018 (n=206,774)</p> ...
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Journal ArticleCancers (Basel) · March 23, 2024
The vaginal microbiome differs by race and contributes to inflammation by directly producing or consuming metabolites or by indirectly inducing host immune response, but its potential contributions to ovarian cancer (OC) disparities remain unclear. In this ...
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Journal ArticleCancer Res Commun · March 18, 2024
UNLABELLED: This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients with ovarian cancer. Th ...
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Other · March 18, 2024
<p>Estimates of the associations between HCA dimensions, patient race and ethnicity, and EOL care quality outcomes on entire study cohort (<i>N</i> = 4,646), subcohort of patients that died from ovarian cancer (<i>N</i> ...
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Other · March 18, 2024
<p>Baseline characteristics of patients with ovarian cancer who died during study follow-up stratified by race and ethnicity (<i>N</i> = 4,646)</p> ...
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Other · March 18, 2024
<p>Relative risk ratio (RR) for receipt of any chemotherapy within 14 days of death with interaction term between accessibility score and patient race</p> ...
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Other · March 18, 2024
<p>Baseline characteristics of patients with ovarian cancer who died during study follow-up stratified by race and ethnicity (<i>N</i> = 4,646)</p> ...
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Journal ArticleGynecol Oncol · August 29, 2024
OBJECTIVE: Ovarian cancer has poor 5-year survival, particularly among non-Hispanic (NH) Black patients. Efforts to identify patients at high-risk of functional limitations and frailty may improve outcomes. In this study, we examined how healthcare access ...
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Journal ArticleCancer Epidemiol · August 1, 2024
We characterized trends in early onset (aged 20-49) cancer incidence by race/ethnicity and sex using the 2011-2020 Surveillance, Epidemiology, and End Results (SEER) Program dataset. We estimated age-standardized cancer incidence rates, incidence rate rati ...
Full textLink to itemCite
Journal ArticleJ Environ Radioact · July 2024
Radon is a naturally occurring radioactive gas that poses significant health risks to humans, including increased risk of lung cancer. This study investigates the association of neighborhood-level socioeconomic variables with radon testing and radon exposu ...
Full textLink to itemCite
Journal ArticleJ Natl Cancer Inst · June 7, 2024
BACKGROUND: Racial and ethnic disparities in genomic testing could exacerbate disparities in access to precision cancer therapies and survival-particularly in the context of lung cancer where genomic testing has been recommended for the past decade. Howeve ...
Full textOpen AccessLink to itemCite
Journal ArticleCancer Epidemiol Biomarkers Prev · June 3, 2024
BACKGROUND: The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer population and examine AI-White dis ...
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Other · June 3, 2024
<p>Supplemental Table S1: Clinical and sociodemographic characteristics of Non-Hispanic American Indian in PRCDA counties and Non-Hispanic White cancer cases diagnosed between 2014-2018 (n=206,774)</p> ...
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Other · June 3, 2024
<p>Supplemental Table S2: Comparison of clinical and sociodemographic characteristics across American Indian classifications for persons diagnosed with cancer between 2014-2018</p> ...
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Other · June 3, 2024
<div>AbstractBackground:<p>The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer ...
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Other · June 3, 2024
<div>AbstractBackground:<p>The American Indian (AI) population in North Carolina has limited access to the Indian Health Service. Consequently, cancer burden and disparities may differ from national estimates. We describe the AI cancer ...
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Other · June 3, 2024
<p>Supplemental Figure S1: Standardized incidence estimates per 100k across classifications of American Indian persons</p> ...
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Other · June 3, 2024
<p>Supplemental Table S2: Comparison of clinical and sociodemographic characteristics across American Indian classifications for persons diagnosed with cancer between 2014-2018</p> ...
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Other · June 3, 2024
<p>Supplemental Figure S1: Standardized incidence estimates per 100k across classifications of American Indian persons</p> ...
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Other · June 3, 2024
<p>Supplemental Table S1: Clinical and sociodemographic characteristics of Non-Hispanic American Indian in PRCDA counties and Non-Hispanic White cancer cases diagnosed between 2014-2018 (n=206,774)</p> ...
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Journal ArticleCancers (Basel) · March 23, 2024
The vaginal microbiome differs by race and contributes to inflammation by directly producing or consuming metabolites or by indirectly inducing host immune response, but its potential contributions to ovarian cancer (OC) disparities remain unclear. In this ...
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Journal ArticleCancer Res Commun · March 18, 2024
UNLABELLED: This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients with ovarian cancer. Th ...
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Other · March 18, 2024
<p>Estimates of the associations between HCA dimensions, patient race and ethnicity, and EOL care quality outcomes on entire study cohort (<i>N</i> = 4,646), subcohort of patients that died from ovarian cancer (<i>N</i> ...
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Other · March 18, 2024
<p>Baseline characteristics of patients with ovarian cancer who died during study follow-up stratified by race and ethnicity (<i>N</i> = 4,646)</p> ...
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Other · March 18, 2024
<p>Relative risk ratio (RR) for receipt of any chemotherapy within 14 days of death with interaction term between accessibility score and patient race</p> ...
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Other · March 18, 2024
<p>Baseline characteristics of patients with ovarian cancer who died during study follow-up stratified by race and ethnicity (<i>N</i> = 4,646)</p> ...
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Other · March 18, 2024
<p>Participant flowchart for NHB, Hispanic and NHW patients with ovarian cancer, SEER-Medicare 2008–2015. Percentage of NHB patients presented for sensitivity purposes.</p> ...
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Other · March 18, 2024
<p>Adjusted count ratio estimates of the associations between HCA dimensions, patient race and ethnicity, and counts of EOL care quality outcomes as count ratios, from fully-adjusted<a href="#tb3fn1" target="_blank"><sup>a</sup ...
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Other · March 18, 2024
<p>Patient, census tract, and regional level variables measuring dimensions of healthcare affordability, availability and accessibility</p> ...
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Other · March 18, 2024
<p>Adjusted count ratio estimates of the associations between HCA dimensions, patient race and ethnicity, and counts of EOL care quality outcomes as count ratios, from fully-adjusted<a href="#tb3fn1" target="_blank"><sup>a</sup ...
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Other · March 18, 2024
<p>Relative risk ratio estimates of the associations between HCA dimensions, patient race/ethnicity, and EOL care quality outcomes</p> ...
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Other · March 18, 2024
<p>Relative risk ratio (RR) for receipt of any chemotherapy within 14 days of death with interaction term between accessibility score and patient race</p> ...
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Other · March 18, 2024
<div>Abstract<p>This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients ...
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Other · March 18, 2024
<p>Estimates of the associations between HCA dimensions, patient race and ethnicity, and EOL care quality outcomes on entire study cohort (<i>N</i> = 4,646), subcohort of patients that died from ovarian cancer (<i>N</i> ...
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Other · March 18, 2024
<p>Relative risk ratio estimates of the associations between HCA dimensions, patient race/ethnicity, and EOL care quality outcomes</p> ...
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Other · March 18, 2024
<div>Abstract<p>This study investigated the association between health care access (HCA) dimensions and racial disparities in end-of-life (EOL) care quality among non-Hispanic Black (NHB), non-Hispanic White (NHW), and Hispanic patients ...
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Other · March 18, 2024
<p>Participant flowchart for NHB, Hispanic and NHW patients with ovarian cancer, SEER-Medicare 2008–2015. Percentage of NHB patients presented for sensitivity purposes.</p> ...
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Other · March 18, 2024
<p>EOL care quality outcomes by patient race and ethnicity (<i>N</i> = 4,646). ICU stay and ER visit outcomes not shown due to cell suppression rules. Outcomes that differ by patient race/ethnicity (<i>χ</i><sup> ...
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Other · March 18, 2024
<p>EOL care quality outcomes by patient race and ethnicity (<i>N</i> = 4,646). ICU stay and ER visit outcomes not shown due to cell suppression rules. Outcomes that differ by patient race/ethnicity (<i>χ</i><sup> ...
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Other · March 18, 2024
<p>Patient, census tract, and regional level variables measuring dimensions of healthcare affordability, availability and accessibility</p> ...
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Journal ArticleCancer Causes Control · March 2024
PURPOSE: The purpose of this study was to assess the association between race/ethnicity and all-cause mortality among women with advanced-stage ovarian cancer who received systemic therapy. METHODS: We analyzed data from the National Cancer Database on wom ...
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Journal ArticleBMC Cancer · July 10, 2023
BACKGROUND: Associations between reproductive factors and breast cancer (BC) risk vary by molecular subtype (i.e., luminal A, luminal B, HER2, and triple negative/basal-like [TNBC]). In this systematic review and meta-analysis, we summarized the associatio ...
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Journal ArticleSci Rep · May 20, 2023
Socioeconomic and racial disparities exist in access to care among patients with non-small cell lung cancer (NSCLC) in the United States. Immunotherapy is a widely established treatment modality for patients with advanced-stage NSCLC (aNSCLC). We examined ...
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Journal ArticleCancer Epidemiol Biomarkers Prev · April 3, 2023
BACKGROUND: Head and neck cancer (HNC) mortality differs by race, ethnicity, and socioeconomic status (SES). However, it is unclear whether the relationship between race/ethnicity and HNC-specific mortality varies according to the residence-level SES. METH ...
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Other · April 3, 2023
<div>AbstractBackground:<p>Head and neck cancer (HNC) mortality differs by race, ethnicity, and socioeconomic status (SES). However, it is unclear whether the relationship between race/ethnicity and HNC-specific mortality varies accordi ...
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Other · April 3, 2023
<p>Table S2 shows demographic and clinical characteristics of patients with primary head and neck cancer by race/ethnicity with missing socioeconomic status.</p> ...
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Other · April 3, 2023
<p>Table S1 shows descriptive statistics of primary head and neck cancer patients with survival time <12 Months by race/ethnicity.</p> ...
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Other · April 3, 2023
<p>Table S3 shows demographic and clinical characteristics of patients with primary head and neck cancer by socioeconomic status.</p> ...
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Other · April 3, 2023
<p>Figure S2 shows cumulative incidence curves by socioeconomic status for the HNC-specific death by race/ethnicity.</p> ...
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Other · April 3, 2023
<p>Table S3 shows demographic and clinical characteristics of patients with primary head and neck cancer by socioeconomic status.</p> ...
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Other · April 3, 2023
<p>Table S6a shows the Cox proportional hazards model for laryngeal cancer, stratified by race/ethnicity and socioeconomic status. Table S6b shows the Cox proportional hazards model for sinonasal cancers, stratified by race/ethnicity and soci ...
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Other · April 3, 2023
<p>Table S1 shows descriptive statistics of primary head and neck cancer patients with survival time <12 Months by race/ethnicity.</p> ...
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Other · April 3, 2023
<p>Table S5a shows the Cox proportional hazards model for oral cavity cancer, stratified by race/ethnicity and socioeconomic status. Table S5b shows the Cox proportional hazards model for pharyngeal cancers, stratified by race/ethnicity and s ...
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Other · April 3, 2023
<p>Table S5a shows the Cox proportional hazards model for oral cavity cancer, stratified by race/ethnicity and socioeconomic status. Table S5b shows the Cox proportional hazards model for pharyngeal cancers, stratified by race/ethnicity and s ...
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Other · April 3, 2023
<p>Figure S2 shows cumulative incidence curves by socioeconomic status for the HNC-specific death by race/ethnicity.</p> ...
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Other · April 3, 2023
<p>Table S2 shows demographic and clinical characteristics of patients with primary head and neck cancer by race/ethnicity with missing socioeconomic status.</p> ...
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Other · April 3, 2023
<p>Table S6a shows the Cox proportional hazards model for laryngeal cancer, stratified by race/ethnicity and socioeconomic status. Table S6b shows the Cox proportional hazards model for sinonasal cancers, stratified by race/ethnicity and soci ...
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Other · April 3, 2023
<div>AbstractBackground:<p>Head and neck cancer (HNC) mortality differs by race, ethnicity, and socioeconomic status (SES). However, it is unclear whether the relationship between race/ethnicity and HNC-specific mortality varies accordi ...
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Journal ArticleCancer Med · April 2023
BACKGROUND: With early intervention, palliative care (PC) can improve quality of life and increase survival among advanced-stage non-small cell lung cancer (aNCSLC) patients. However, PC is often offered late in the cancer treatment course and is underused ...
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Journal ArticleCancer Med · April 2023
BACKGROUND: Cytopenia is associated with cancer through mechanisms including clonal hematopoiesis and chronic inflammation. Cytopenia is more prevalent in Black people but its relationship with racial disparities in cancer mortality is unknown. METHODS: Cy ...
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Journal ArticleJNCI Cancer Spectr · March 1, 2023
BACKGROUND: Racial and ethnic disparities in ovarian cancer (OC) survival are well-documented. However, few studies have investigated how health-care access (HCA) contributes to these disparities. METHODS: To evaluate the influence of HCA on OC mortality, ...
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Journal ArticleCancer Epidemiol Biomarkers Prev · January 9, 2023
BACKGROUND: Ovarian cancer survival disparities have persisted for decades, driven by lack of access to quality treatment. We conducted structural equation modeling (SEM) to define latent variables representing three healthcare access (HCA) domains: afford ...
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Journal ArticleCancers (Basel) · December 19, 2022
Several proposed theoretical frameworks have defined the complex nature of healthcare access (HCA) [...]. ...
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Journal ArticleJ Pain Symptom Manage · December 2022
OBJECTIVE: Lack of access to supportive care (SC) among cancer patients have been well documented. However, the role of affordability in this disparity among ovarian cancer (OC) patients remain poorly understood. METHODS: Patients with OC between 2008 and ...
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ConferenceJCO Oncology Practice · October 1, 2022
PURPOSE:People living with HIV (PLWH) diagnosed with cancer are less likely to receive quality cancer treatment compared with HIV-negative patients. Timely provision of palliative care (PC) during cancer treatment can increase patient's survival and improv ...
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Journal ArticleJCO Oncol Pract · October 2022
PURPOSE: People living with HIV (PLWH) diagnosed with cancer are less likely to receive quality cancer treatment compared with HIV-negative patients. Timely provision of palliative care (PC) during cancer treatment can increase patient's survival and impro ...
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Journal ArticleCancer · August 15, 2022
BACKGROUND: This study examined whether the association of socioeconomic status (SES) and non-small cell lung cancer (NSCLC) stage varied by race/ethnicity and health care access measures. METHODS: This study used data from the 2004-2016 National Cancer Da ...
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Journal ArticleCancer Epidemiol Biomarkers Prev · July 1, 2022
BACKGROUND: Differential access to quality care is associated with racial disparities in ovarian cancer survival. Few studies have examined the association of multiple healthcare access (HCA) dimensions with racial disparities in quality treatment metrics, ...
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Journal ArticleSci Rep · June 23, 2022
There is conflicting evidence on the role of lipid biomarkers in breast cancer (BC), and no study to our knowledge has examined this association among African women. We estimated odds ratios (ORs) and 95% confidence intervals (95% CI) for the association o ...
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Journal ArticleClin Breast Cancer · June 2022
BACKGROUND: Metabolic syndrome (MetS) is characterized by a cluster of biological irregularities. The purpose of this analysis was to examine the association of MetS with BC among Nigerian women, and for the first time evaluate this association by molecula ...
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Journal ArticleJ Immunother · February 2022
Lung cancer is the most common cause of cancer death among men and women in the United States, with significant racial disparities in survival. It is unclear whether these disparities persist upon equal utilization of immunotherapy. The purpose of this stu ...
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Journal ArticleCancer · January 1, 2022
BACKGROUND: Social determinants of health (SDOHs) cluster together and can have deleterious impacts on health outcomes. Individually, SDOHs increase the risk of cancer mortality, but their cumulative burden is not well understood. The authors sought to det ...
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Journal ArticlePLoS One · 2022
BACKGROUND: Aflatoxin suppresses cellular immunity and accentuates HIV-associated changes in T- cell phenotypes and B- cells. OBJECTIVE: This prospective study was conducted to examine the association of aflatoxin levels with CD4 T-cell count and antiretro ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · January 1, 2022
AbstractBackground: Lung cancer is the most common cause of cancer death among men and women in the United States, with 85% of all cases characterized as non-small cell lung cancer (NSCLC). These cancers are ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · January 1, 2022
AbstractPurpose: Ovarian cancer is the most lethal gynecological cancer and despite advances in treatment, most patients are diagnosed at an advanced stage with poor prognosis. Black women have a lower 5 yea ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · January 1, 2022
AbstractBackground: The African continent experiences the highest age-standardized breast cancer mortality globally, with Nigeria reporting the highest rate within the continent. Breast cancer in Nigeria is ...
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Journal ArticleFront Public Health · 2022
Cancer incidence and mortality rates continue to rise globally, a trend mostly driven by preventable cancers occurring in low-and middle-income countries (LMICs). There is growing concern that many LMICs are ill-equipped to cope with markedly increased bur ...
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Journal ArticleJ Natl Cancer Inst · November 29, 2021
BACKGROUND: Although Medicaid expansion is associated with decreased uninsured rates and earlier cancer diagnoses, no study has demonstrated an association between Medicaid expansion and cancer mortality. Our primary objective was to quantify the relations ...
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Journal ArticleAnn Am Thorac Soc · November 2021
Rationale: Although lung cancer screening (LCS) with low-dose computed tomography (LDCT) is now recommended for those meeting standard risk factor-based eligibility criteria, the role of comorbidity in the uptake of LCS with LDCT in an older real-world U.S ...
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Journal ArticleBMJ Open · October 4, 2021
INTRODUCTION: Less than 40% of patients with ovarian cancer (OC) in the USA receive stage-appropriate guideline-adherent surgery and chemotherapy. Black patients with cancer report greater depression, pain and fatigue than white patients. Lack of access to ...
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Journal ArticleMol Carcinog · October 2021
Forkhead box class O (FOXO) transcription factors play a pivotal role in regulating a variety of biological processes, including organismal development, cell signaling, cell metabolism, and tumorigenesis. Therefore, we hypothesize that genetic variants in ...
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Journal ArticleBMC Cancer · September 25, 2021
BACKGROUND: The association between obesity and breast cancer (BC) has been extensively studied among US, European and Asian study populations, with often conflicting evidence. However, despite the increasing prevalence of obesity and associated conditions ...
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Journal ArticleEur J Nutr · September 2021
PURPOSE: Evolutionary discordance may contribute to the high burden of chronic disease-related mortality in modern industrialized nations. We aimed to investigate the associations of a 7-component, equal-weight, evolutionary-concordance lifestyle (ECL) sco ...
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Journal ArticleOncotarget · June 22, 2021
Breast cancer (BC) in Nigeria is characterized by disproportionately aggressive molecular subtypes. C-reactive protein (CRP) is associated with risk and aggressiveness for several types of cancer. We examined the association of high-sensitivity CRP (hsCRP) ...
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Journal ArticleInt J Environ Res Public Health · June 4, 2021
Palliative care improves quality-of-life and extends survival, however, is underutilized among gynecological cancer patients in the United States (U.S.). Our objective was to evaluate associations between healthcare access (HCA) measures and palliative car ...
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Journal ArticleJ Clin Apher · June 2021
BACKGROUND: Heparin-induced thrombocytopenia (HIT) is characterized by anti-heparin/platelet factor 4 immune complexes, which are removed by therapeutic plasma exchange (TPE). Our main objective was to study TPE outcomes in HIT using a large administrative ...
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Journal ArticlePrev Med · June 2021
The objective of this study is to provide an assessment of allostatic load (AL) burden among US adults across race/ethnicity, gender, and age groups over a 30-year time period. We analyzed data from 50,671 participants of the National Health and Nutrition ...
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Journal ArticleJ Immunother · June 1, 2021
In patients with metastatic non-small cell lung cancer (mNSCLC), the extent to which immunotherapy utilization rate varies by comorbidities is unclear. Using the National Cancer Database from 2015 to 2016, we assessed the association between levels of como ...
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Journal ArticleBreast Cancer Res Treat · April 2021
PURPOSE: To examine patterns of de-novo metastases (mets) and association with breast cancer-specific mortality across subtypes and racial groups. METHODS: Non-Hispanic (NH) Black and NH-White patients ages 40 years and older with primary breast cancer (BC ...
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Journal Article · March 10, 2021
AbstractPurpose: There is conflicting evidence on the role of lipid biomarkers in breast cancer (BC), and no study to our knowledge has examined this association among African women.
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Journal ArticleGynecol Oncol · February 2021
BACKGROUND: Palliative care (PC) is recommended for gynecological cancer patients to improve survival and quality-of-life. Our objective was to evaluate racial/ethnic disparities in PC utilization among patients with metastatic gynecologic cancer. METHODS: ...
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Journal ArticleData Brief · February 2021
The National Comprehensive Cancer Network recommends palliative care should be integrated in to cancer care starting from cancer diagnosis. However, traditionally palliative care is prioritized for cancer patients at the end-of-life. In our main article ti ...
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Journal ArticleBMC Med · January 8, 2021
BACKGROUND: Human immunodeficiency virus (HIV) remains a public health priority in Latin America. While the burden of HIV is historically concentrated in urban areas and high-risk groups, subnational estimates that cover multiple countries and years are mi ...
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Journal ArticleNature · January 2021
The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income ...
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Journal ArticleFront Public Health · 2021
Objective: In China, cancer accounts for one-fifth of all deaths, and exerts a heavy toll on patients, families, healthcare systems, and society as a whole. This study aims to examine the temporal trends in socio-economic and rural-urban differences in tre ...
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Journal ArticleAnn Glob Health · 2021
BACKGROUND: Nigeria reports the highest age-standardized mortality rate for breast cancer (BC) among African countries and disproportionately high rates of high-grade cancer. Histological grade is a strong predictor of mortality, and evidence suggests that ...
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Journal ArticleJ Intensive Care Med · December 2020
BACKGROUND: Few studies have examined whether community factors mediate the relationship between patients surviving cancer and future development of sepsis. We determined the influence of community characteristics upon risk of sepsis after cancer, and whet ...
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Journal ArticleLancet · October 17, 2020
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 ...
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Journal ArticleLancet · October 17, 2020
BACKGROUND: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study ...
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Journal ArticleLancet · October 17, 2020
BACKGROUND: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries ...
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Journal ArticleLancet · October 17, 2020
BACKGROUND: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. Th ...
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Journal ArticleJAMA Oncol · August 1, 2020
IMPORTANCE: Sedentary behavior is associated with several health outcomes, including diabetes, cardiovascular disease, and all-cause mortality. Less is known about the association between objectively measured sedentary behavior and cancer mortality, as wel ...
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Journal ArticleNat Med · August 2020
An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
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Journal ArticleJ Intensive Care Med · July 2020
BACKGROUND: Cancer survivors are at increased risk of sepsis, possibly attributed to weakened physiologic conditions. The aims of this study were to examine the mediation effect of indicators of frailty on the association between cancer survivorship and se ...
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Journal ArticleCancers (Basel) · June 26, 2020
Among 29,701 Black and White participants aged 45 years and older in the Reasons forGeographic and Racial Difference in Stroke (REGARDS) study, allostatic load (AL) was defined asthe sum score of established baseline risk-associated biomarkers for which pa ...
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Journal ArticleLancet Gastroenterol Hepatol · June 2020
BACKGROUND: Oesophageal cancer is a common and often fatal cancer that has two main histological subtypes: oesophageal squamous cell carcinoma and oesophageal adenocarcinoma. Updated statistics on the incidence and mortality of oesophageal cancer, and on t ...
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Journal ArticleNat Med · May 2020
A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- ...
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Journal ArticleJCO Glob Oncol · April 2020
PURPOSE: Cervical cancer screening is not well implemented in many low- and middle-income countries (LMICs). Mobile health (mHealth) refers to utilization of mobile technologies in health promotion and disease management. We aimed to qualitatively synthesi ...
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Journal ArticleLancet Gastroenterol Hepatol · March 2020
BACKGROUND: Cirrhosis and other chronic liver diseases (collectively referred to as cirrhosis in this paper) are a major cause of morbidity and mortality globally, although the burden and underlying causes differ across locations and demographic groups. We ...
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Journal ArticleOccup Environ Med · March 2020
OBJECTIVES: This study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study. METHODS: The GBD 2016 study estimated the ...
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Journal ArticleOccup Environ Med · March 2020
OBJECTIVES: This study provides a detailed analysis of the global and regional burden of cancer due to occupational carcinogens from the Global Burden of Disease 2016 study. METHODS: The burden of cancer due to 14 International Agency for Research on Cance ...
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Journal ArticleOncotarget · February 18, 2020
This article has been corrected: The third author in the listing, along with a new affiliation, has been added as follows: Daniel Tefera Dibaba3 3Tennessee Clinical and Translational Science Institute, University of Tennessee Health Science Center, Memphis ...
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Journal ArticleLancet Gastroenterol Hepatol · January 2020
BACKGROUND: Stomach cancer is a major health problem in many countries. Understanding the current burden of stomach cancer and the differential trends across various locations is essential for formulating effective preventive strategies. We report on the i ...
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Journal ArticleNature · January 2020
Educational attainment is an important social determinant of maternal, newborn, and child health1-3. As a tool for promoting gender equity, it has gained increasing traction in popular media, international aid strategies, and global agenda-setting4-6. The ...
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Journal ArticleAm J Cancer Res · 2020
Vitamin D has a potential anticarcinogenic role, possibly through regulation of cell proliferation and differentiation, stimulation of apoptosis, immune modulation and regulation of estrogen receptor levels. Because breast cancer (BC) risk varies among ind ...
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Journal ArticleJAMA Oncol · December 1, 2019
IMPORTANCE: Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the ...
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Journal ArticleCancer Epidemiol · December 2019
BACKGROUND: Little is known about outcomes in patients after being hospitalized for care of cancer or comorbid conditions and the disparity between African-American and White cervical cancer patients. METHODS: Using the national inpatient sample (HCUP-NIS) ...
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Journal ArticleLancet Gastroenterol Hepatol · December 2019
BACKGROUND: Worldwide, both the incidence and death rates of pancreatic cancer are increasing. Evaluation of pancreatic cancer burden and its global, regional, and national patterns is crucial to policy making and better resource allocation for controlling ...
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Journal ArticleLancet Gastroenterol Hepatol · December 2019
BACKGROUND: Data about the global, regional, and country-specific variations in the levels and trends of colorectal cancer are required to understand the impact of this disease and the trends in its burden to help policy makers allocate resources. Here we ...
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Journal ArticleJNCI Cancer Spectr · December 2019
BACKGROUND: Ovarian cancer remains a leading cause of death from gynecological malignancies. Race, socioeconomic status (SES), and access to health care are important predictors of quality treatment and survival. We provide a systematic review and meta-ana ...
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Journal ArticlePrev Med Rep · September 2019
The objective of this study was to estimate the influence of the Affordable Care Act (ACA) Medicaid Expansion on current smoking and quit attempts in expanded and non-expanded states. We analyzed data from the Behavioral Risk Factor Surveillance System (BR ...
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Journal ArticleOncotarget · August 6, 2019
This study examines the association between inflammatory biomarkers and risk of cancer mortality by race. Data were obtained from 1,856 participants in the prospective REGARDS cohort who were cancer-free at baseline, and analyzed in relation to cancer mort ...
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Journal ArticleJ Glob Oncol · June 2019
PURPOSE: To elucidate the role of metabolic dysregulation and associated DNA methylation changes on breast cancer risk and aggressive subtypes among Nigerian women. We describe the design and methods of a collaborative molecular epidemiology study of breas ...
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Journal ArticleLancet · May 11, 2019
BACKGROUND: Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate the consumption of major foods and nutri ...
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Journal ArticleMetabolism · May 2019
OBJECTIVE: To investigate the association between biomarkers of inflammation and metabolic dysregulation and cancer mortality by obesity status. METHODS: Data from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort was used to exa ...
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Journal ArticleJ Geriatr Oncol · March 2019
OBJECTIVES: We examined the association between three inflammatory markers (Interleukin (IL)-6, C-reactive protein (CRP), tumor necrosis factor (TNF)-α) and incident lung cancer using baseline, updated, and averaged inflammatory measures in older adults. M ...
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Journal ArticleFront Biosci (Schol Ed) · March 1, 2019
African-American (AA) women are more likely to die from breast cancer (BC), at any age, compared to European-American women. Although breakthroughs in pre-clinical studies have resulted in potentially actionable targets in AA BC, drugs that were rationally ...
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Journal ArticleBreast Cancer Res Treat · February 2019
PURPOSE: To investigate the association between metabolic syndrome (MetS) and risk of breast cancer mortality by menopausal status, obesity, and subtype. METHODS: Data from 94,555 women free of cancer at baseline in the National Institute of Health-America ...
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Journal ArticleCancer Control · 2019
BACKGROUND: Prior data suggests that breast cancer screening rates are lower among women in the Appalachian region of the United States. This study examined the changes in breast cancer screening before and after the implementation of the Affordable Care A ...
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Journal ArticleJ Glob Health · December 2018
BACKGROUND: The burden of non-communicable diseases has increased rapidly in low- and middle-income countries. Past studies have reported an association between socioeconomic status (SES) and cardio-metabolic risk factors, but most have focused on upper in ...
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Journal ArticleLancet · November 10, 2018
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 comparative risk assessment (CRA) is a comprehensive approach to risk factor quantification that offers a useful tool for synthesising evidence on risks and risk-outcome ...
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Journal ArticleLancet · November 10, 2018
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 20 ...
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Journal ArticleLancet · November 10, 2018
BACKGROUND: Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global B ...
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Journal ArticleLancet · November 10, 2018
BACKGROUND: Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates of population and fertility, alth ...
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Journal ArticleLancet · November 10, 2018
BACKGROUND: Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no on ...
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Journal ArticleLancet · November 10, 2018
BACKGROUND: How long one lives, how many years of life are spent in good and poor health, and how the population's state of health and leading causes of disability change over time all have implications for policy, planning, and provision of services. We c ...
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Journal ArticleJAMA Oncol · November 1, 2018
IMPORTANCE: The increasing burden due to cancer and other noncommunicable diseases poses a threat to human development, which has resulted in global political commitments reflected in the Sustainable Development Goals as well as the World Health Organizati ...
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Journal ArticleLancet · September 22, 2018
BACKGROUND: Alcohol use is a leading risk factor for death and disability, but its overall association with health remains complex given the possible protective effects of moderate alcohol consumption on some conditions. With our comprehensive approach to ...
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Journal ArticleCancers (Basel) · September 1, 2018
The objective of this study was to investigate the association of metabolic syndrome (MetS) with the risk of invasive breast cancer and molecular subtypes across race, menopause, and body mass index (BMI) groups. We examined the association of metabolic sy ...
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Journal ArticleInt J Public Health · September 2018
OBJECTIVES: We conducted a systematic review of the literature relating early life socioeconomic position (SEP) to breast cancer incidence and mortality from a critical period and life-course trajectory perspective. METHODS: PubMed, EMBASE and Web of Scien ...
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Journal ArticleCancer Epidemiol · August 2018
BACKGROUND: Hospitalized cancer patients are nearly 10 times more likely to develop sepsis when compared to patients with no cancer history. We compared the risk of sepsis between cancer survivors and no cancer history participants, and examined whether ra ...
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Journal ArticleCancer Causes Control · August 2018
PURPOSE: The goals of this study were to identify geographic and racial/ethnic variation in breast cancer mortality, and evaluate whether observed geographic differences are explained by county-level characteristics. METHODS: We analyzed data on breast can ...
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ConferenceCancer Research · July 1, 2018
AbstractINTRODUCTION: The obesogenic milieu is a pro-tumorigenic environment that promotes tumor initiation, angiogenesis and metastasis. In this prospective cohort, we examined the association between pre-d ...
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Journal ArticleLancet · June 2, 2018
BACKGROUND: A key component of achieving universal health coverage is ensuring that all populations have access to quality health care. Examining where gains have occurred or progress has faltered across and within countries is crucial to guiding decisions ...
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Journal ArticleSupport Care Cancer · June 2018
PURPOSE: Sleep disturbances are recognized as a problem for many cancer patients, but little is known about the prevalence of sleep disorders among women hospitalized with breast cancer, or their relationship to in-hospital outcomes. The present study repr ...
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Journal ArticleJAMA · April 10, 2018
INTRODUCTION: Several studies have measured health outcomes in the United States, but none have provided a comprehensive assessment of patterns of health by state. OBJECTIVE: To use the results of the Global Burden of Disease Study (GBD) to report trends i ...
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Journal ArticleCancer Med · April 2018
Racial disparities in cancer mortality still exist despite improvements in treatment strategies leading to improved survival for many cancer types. In this study, we described race/ethnic differences in patterns of de novo metastasis and evaluated the asso ...
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Journal ArticleOncotarget · March 23, 2018
INTRODUCTION: The obesogenic milieu is a pro-tumorigenic environment that promotes tumor initiation, angiogenesis and metastasis. In this prospective cohort, we examined the association between pre-diagnostic metabolic biomarkers, plasma adiponectin, resis ...
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Journal ArticleObes Surg · March 2018
BACKGROUND: Metabolic syndrome (MetS) is an important etiologic and prognostic factor for cancer, but few studies have assessed hospitalization outcomes among patients with both conditions. METHODS: Data was obtained from the Healthcare Cost and Utilizatio ...
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Journal ArticleCancer Causes Control · March 2018
BACKGROUND: This study examines whether racial disparities in hospitalization outcomes persist between African-American and White women with ovarian cancer after matching on demographic, presentation, and treatment factors. METHODS: Using data from the Nat ...
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Journal ArticleObesity (Silver Spring) · January 2018
OBJECTIVE: This study examined whether metabolic health status is associated with risk of cancer mortality and whether this varies by body mass index (BMI) category. METHODS: A prospective study of 22,514 participants from the Reasons for Geographic and Ra ...
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Journal ArticleClin Interv Aging · 2018
BACKGROUND: The extent to which screening mammography (SM) recommendations in older women incorporate life expectancy factors is not well established. OBJECTIVE: The objective of this review was to evaluate evidence on SM utilization in older women by life ...
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Journal ArticleClin Epigenetics · 2018
BACKGROUND: The high prevalence of obesity among US adults has resulted in significant increases in associated metabolic disorders such as diabetes, dyslipidemia, and high blood pressure. Together, these disorders constitute metabolic syndrome, a clinicall ...
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Journal ArticleAnn Epidemiol · January 2018
PURPOSE: Racial disparities exist in the prevalence of cancer-related risk factors and incidence of cancer. The objective of this study is to determine if cancer-related risk factors mediate the association between race and cancer incidence. METHODS: We pe ...
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Journal ArticleBMC Cancer · December 15, 2017
BACKGROUND: We examined the association between metabolic dysregulation and cancer mortality in a prospective cohort of Black and White adults. METHODS: A total of 25,038 Black and White adults were included in the analysis. Metabolic dysregulation was def ...
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Journal ArticleInt J Cancer · December 1, 2017
Proinflammatory dietary patterns have been associated with increased cancer risk and mortality. We present a systematic review and meta-analysis of the current published literature on a dietary inflammatory index (DII) score and its association with cancer ...
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Journal ArticleJAMA Oncol · December 1, 2017
IMPORTANCE: Liver cancer is among the leading causes of cancer deaths globally. The most common causes for liver cancer include hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and alcohol use. OBJECTIVE: To report results of the Global Burden ...
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Journal ArticleDiabetes Metab Syndr · December 2017
AIMS: Metabolic Syndrome (MetS) is an important etiologic and prognostic factor for pancreatic cancer, but few studies have assessed health outcomes among hospitalized pancreatic cancer patients. We examined the associations between MetS and in-hospital ou ...
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Journal ArticleLancet · September 16, 2017
BACKGROUND: Detailed assessments of mortality patterns, particularly age-specific mortality, represent a crucial input that enables health systems to target interventions to specific populations. Understanding how all-cause mortality has changed with respe ...
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Journal ArticleLancet · September 16, 2017
BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and pro ...
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Journal ArticlePrev Med · September 2017
This study examined trends in smoking and overweight/obesity rates among United States (US) adults ages 40years and older by race and socio-economic status (SES) across three study periods; pre-recession (2003-2005), recession (2007-2009), and post-recessi ...
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Journal ArticlePrev Med Rep · September 2017
The aim of this study is examine trends in breast and colorectal cancer screening in the U.S. by race, healthcare coverage, and socio-economic status (SES) before the Great Recession (2003-2005), during the recession (2007-2009), and post-recession/Afforda ...
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Journal ArticleBMC Cancer · August 30, 2017
BACKGROUND: Racial disparities in the incidence of major cancers may be attributed to differences in the prevalence of established, modifiable risk factors such as obesity, smoking, physical activity and diet. METHODS: Data from a prospective cohort of 566 ...
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Journal ArticleJ Ovarian Res · August 22, 2017
BACKGROUND: The purpose of this study is to examine whether racial disparities in epithelial ovarian cancer stage at diagnosis and survival may be explained by geographic availability of healthcare resources among Blacks and Whites. METHODS: Data from the ...
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Journal ArticleCancer Epidemiol · August 2017
BACKGROUND: The purpose of this study is to determine if racial disparities in inpatient outcomes persist among hospitalized patients comparing African American and White breast cancer patients matched on demographics, presentation and treatment. METHODS: ...
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Journal ArticleCancer Epidemiol · August 2017
INTRODUCTION: The aims of this study were to identify counties in the United States (US) with high rates of lung cancer mortality, and to characterize the associated community-level factors while focusing on particulate-matter pollution. METHODS: We perfor ...
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Journal ArticleLancet · July 15, 2017
BACKGROUND: National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality ...
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ConferenceCancer Research · July 1, 2017
AbstractBackground: The epidemic of obesity among US adults has resulted in significant increases in associated metabolic disorders such as diabetes, dyslipidemia and high blood pressure. Together, these dis ...
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Journal ArticlePrev Chronic Dis · March 16, 2017
INTRODUCTION: Metabolic syndrome is a cluster of cardiometabolic risk factors associated with increased risk of multiple chronic diseases, including cancer and cardiovascular disease. The objectives of this study were to estimate the prevalence of metaboli ...
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Journal ArticleBMC Public Health · February 21, 2017
BACKGROUND: Cervical Cancer (CC) is the number one cancer among women in sub-Saharan Africa. Although CC is preventable, most women in developing countries do not have access to screening. METHODS: This cross-sectional study was conducted to determine the ...
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Journal ArticleInt J Cancer · February 15, 2017
Few studies have examined cancer-related risk factors in relation to SES across the lifecourse in low to middle income countries. This analysis focuses on adult women in India, China, Mexico, Russia and South Africa, and examines the association between in ...
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Journal ArticleCancer Epidemiol · February 2017
OBJECTIVES: This paper aims to determine whether racial disparities exist in hospitalization outcomes among African-American and White hospitalized prostate cancer patients in the United States. We evaluated racial differences among matched groups of patie ...
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Journal ArticleJAMA · January 10, 2017
IMPORTANCE: Elevated systolic blood (SBP) pressure is a leading global health risk. Quantifying the levels of SBP is important to guide prevention policies and interventions. OBJECTIVE: To estimate the association between SBP of at least 110 to 115 mm Hg a ...
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Journal ArticleJ Stroke Cerebrovasc Dis · January 2017
BACKGROUND: Carotid endarterectomy and carotid artery stenting are effective treatment procedures for carotid artery stenosis. Although diabetes mellitus is highly prevalent among patients undergoing these revascularization procedures, few studies have exa ...
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Journal ArticleAnn Glob Health · 2017
BACKGROUND: Recent trends toward urbanization in developing countries like Ghana, coupled with nutritional transition and aging populations, have led to a rapid increase in the prevalence of noncommunicable diseases such as obesity, diabetes, and hypertens ...
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Journal ArticleCancer Med · January 2017
The purpose of this paper is to examine the relationship between marijuana use and health outcomes among hospitalized patients, including those hospitalized with a diagnosis of cancer. A total of 387,608 current marijuana users were identified based on ICD ...
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Journal ArticleGenetics · January 2017
Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer patients has been a persistent problem for many decades. Currently, prognosis and outcome predictions are made based on clinical factors and/or by incorporating molecular ...
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Journal ArticlePLoS One · 2017
BACKGROUND: The purpose of this review was to summarize the published literature on the association of childhood, adulthood and life course socio-economic status (SES) with obesity between January 1990 and June 2015. METHODS: The major medical electronic d ...
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Journal ArticleRes Rep Trop Med · 2017
Objective: Our study describes the 2014 Chikungunya outbreak in Western Jamaica in terms of geographic distribution and trend of the outbreak over time, and evaluates clinical symptoms of the disease based on pre-existing conditions. Methods: We conducted ...
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Chapter · January 1, 2017
Cancer remains a significant global public health issue, with 17.5 million incident cancer cases and 8.7 million cancer deaths in 2015. Although traditional epidemiology methods have significantly improved understanding of etiologic and prognostic risk fac ...
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Journal ArticleBMJ Open · November 22, 2016
OBJECTIVES: Socioeconomic differences in screening have been well documented in upper-income countries; however, few studies have examined socioeconomic status (SES) over the life-course in relation to cancer screening in lower-income and middle-income cou ...
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Journal ArticleInt J Cancer · November 15, 2016
Marked racial differences exist in dietary patterns and obesity, as well as cancer mortality. This study aims to assess whether dietary patterns are associated with cancer mortality overall and by race. We identified 22,041 participants from the REasons fo ...
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Journal ArticleInt J Equity Health · November 15, 2016
BACKGROUND: Obesity rates have continued to increase over time globally, resulting in an increase in the burden of obesity-associated chronic diseases. There is a paucity of research on the association between obesity and generational changes in socio-econ ...
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Journal ArticleLancet · October 8, 2016
BACKGROUND: Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-caus ...
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Journal ArticleLancet · October 8, 2016
BACKGROUND: In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 health-related SDG indicator ...
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Journal ArticleLancet · October 8, 2016
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning th ...
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Journal ArticleLancet · October 8, 2016
BACKGROUND: Established in 2000, Millennium Development Goal 4 (MDG4) catalysed extraordinary political, financial, and social commitments to reduce under-5 mortality by two-thirds between 1990 and 2015. At the country level, the pace of progress in improv ...
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Journal ArticleLancet · October 8, 2016
BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame ...
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Journal ArticleBMC Cancer · September 5, 2016
BACKGROUND: The purpose of this study was to examine racial and socio-economic differences in the receipt of laparoscopic or open surgery among patients with colorectal cancer, and to determine if racial and socio-economic differences exist in post-surgica ...
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Journal ArticleThe Lancet HIV · September 1, 2016
GBD 2015 HIV Collaborators. Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: the Global Burden of Disease Study 2015. Lancet HIV 2016; 3: e361–87—In this Article, Kerrie E Doyle and David M Pereira have be ...
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Journal ArticleData Brief · September 2016
The high prevalence of comorbidities among US adults is a major public health problem. However, there is limited data on the geographic distribution of comorbidities. In addition, recent changes to health insurance programs in the US through the Affordable ...
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Journal ArticleJ Bioinform Genom · September 2016
MOTIVATION: Many traditional clinical prognostic factors have been known for cancer for years, but usually provide poor survival prediction. Genomic information is more easily available now which offers opportunities to build more accurate prognostic model ...
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Journal ArticleLancet HIV · August 2016
BACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS inciden ...
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Journal ArticleCancer Epidemiol · August 2016
BACKGROUND: Breast cancer remains a major cause of morbidity and mortality among women in the US, and despite numerous studies documenting racial disparities in outcomes, the survival difference between Black and White women diagnosed with breast cancer co ...
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Journal ArticleAnn Epidemiol · August 2016
PURPOSE: Rapid infant and childhood growth has been associated with chronic disease later in life, including breast cancer. Early life socioeconomic status (SES) influences childhood growth, but few studies have prospective measures from birth to consider ...
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ConferenceCancer Research · July 15, 2016
AbstractIntroduction: Complex biological pathways link metabolic dysregulation (obesity, hypertension, dyslipidemia and diabetes) with cancer tumorigenesis, progression and metastasis, and those include high ...
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Journal ArticlePrev Med · July 2016
INTRODUCTION: About 92% of US older adults have at least one chronic disease or medical condition and 77% have at least two. Low-income and uninsured adults in particular experience a higher burden of comorbidities, and the Medicaid expansion provision of ...
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Journal ArticleMedicine (Baltimore) · July 2016
IMPORTANCE: Over one-third of American adults (36%) are obese and more than two-thirds (69%) are overweight. The impact of obesity on hospitalization outcomes is not well understood. OBJECTIVE: To examine the association between body mass index (BMI) and o ...
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Journal ArticleBreast Cancer Res Treat · June 2016
The aim of the study is to determine the influence of area-level socio-economic status and healthcare access in addition to tumor hormone-receptor subtype on individual breast cancer stage, treatment, and mortality among Non-Hispanic (NH)-Black, NH-White, ...
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Journal ArticleInt Health · May 2016
BACKGROUND: Cancer prevention guidelines have been developed to improve knowledge and adherence to modifiable cancer risk factors. The implementation of these guidelines has largely been studied in North American and European populations. The aim of this s ...
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Journal ArticleJ Community Health · April 2016
This study aims to examine if access to healthcare, measured through the availability of medical resources at the neighborhood level, influences colorectal cancer (CRC) stage, treatment and survival using the Surveillance Epidemiology and Ends Result (SEER ...
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Journal ArticleToxins (Basel) · November 30, 2015
The association between aflatoxin exposure and alteration in immune responses observed in humans suggest that aflatoxin could suppress the immune system and work synergistically with HIV to increase disease severity and progression to AIDS. No longitudinal ...
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Journal ArticleCancer Epidemiol · October 2015
BACKGROUND: The purpose of this study is to evaluate racial and socio-economic differences in breast cancer surgery treatment, post-surgical complications, hospital length of stay and mortality among hospitalized breast cancer patients. METHODS: We examine ...
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Journal ArticleBreast Cancer Res Treat · August 2015
Breast cancer accounts for over 200,000 annual cases among women in the United States, and is the second leading cause of cancer-related deaths. However, few studies have investigated the association between breast cancer subtype and survival among African ...
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Journal ArticleBMC Public Health · April 15, 2015
BACKGROUND: Cervical cancer is the most commonly diagnosed cancer and the leading cause of cancer mortality among women in sub-Saharan Africa. Recent recommendations for cervical cancer primary prevention highlight HPV vaccination, and secondary prevention ...
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ConferenceCancer Epidemiology, Biomarkers & Prevention · April 1, 2015
AbstractBreast cancer (BC) incidence varies across countries and across US ethnic groups. US Immigrants often exhibit an intermediate level of risk between those observed in their birth country and in the US ...
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Journal ArticleBMC Cancer · March 28, 2015
BACKGROUND: Factors beyond the individual level such as those characterizing the residential environment may be important to breast cancer outcomes. We provide a systematic review and results of meta-analysis of the published empirical literature on the as ...
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Journal ArticleSpringerplus · 2015
Recent developments in genetics and molecular biology have classified breast cancer into subtypes based on tumor markers of estrogen (ER), progesterone (PR) and human epidermal growth Factor-2 receptors (Her-2), with the basal-like (ER-, PR-, Her2-) subtyp ...
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Journal ArticlePLoS One · 2015
PURPOSE: To document the prevalence of depression and anxiety disorders, and their associations with mortality among hospitalized breast cancer patients. METHODS: We examined the associations between breast cancer diagnosis and the diagnoses of anxiety or ...
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Journal ArticlePLoS One · 2014
BACKGROUND: Cancer rates in Africa are projected to double by 2030 due to aging and increased exposure to cancer risk factors, including modifiable risk factors. We assessed adherence to 5 modifiable cancer risk factors across 18 African countries. METHODS ...
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Journal ArticlePLoS One · 2013
The long-term effect of socioeconomic status (SES) and healthcare resources availability (HCA) on breast cancer stage of presentation and mortality rates among patients in Michigan is unclear. Using data from the Michigan Department of Community Health (MD ...
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Journal ArticleJ Cancer Epidemiol · 2013
Background. Breast cancer survival has improved significantly in the US in the past 10-15 years. However, disparities exist in breast cancer survival between black and white women. Purpose. To investigate the effect of county healthcare resources and SES a ...
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Journal ArticleInt J Equity Health · March 21, 2012
BACKGROUND: Breast cancer screening rates have increased over time in the United States. However actual screening rates appear to be lower among black women compared with white women. PURPOSE: To assess determinants of breast cancer screening among women i ...
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Journal ArticlePLoS One · 2012
BACKGROUND: Breast and Cervical cancer are the two most common cancers among women in developing countries. Regular screening is the most effective way of ensuring that these cancers are detected at early stages; however few studies have assessed factors t ...
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