Christopher Ignatius Shaffrey

Journal Article J Clin Neurosci · April 2025 Radiographic parameters for diagnosing cervical neuroforaminal stenosis (CNFS) are not well described. To develop definitive criteria for diagnosis of CNFS, a standardized baseline of average neuroforaminal dimensions must first be established. Thus, the a ... Full text Open Access Link to item Cite

Impact of Enhanced Recovery After Surgery Protocols on Outcomes Up to Two Years After Adult Structural Spine Disorder Surgery.

Journal Article Spine (Phila Pa 1976) · March 15, 2025 STUDY DESIGN: Retrospective cohort study of prospectively enrolled database. OBJECTIVE: We analyze the recovery pattern of patients with adult structural spine disorder (ASD) who underwent corrective surgery with enhanced recovery after surgery (ERAS+) pro ... Full text Open Access Link to item Cite

Antibiotic Use in Adult Spine Deformity Surgery: Results From the AO Spine Surveillance of the Management of Patients With Adult Spine Deformity.

Journal Article Global Spine J · March 2025 STUDY DESIGN: Cross-sectional international survey with literature review. OBJECTIVES: To evaluate the evidence for these strategies and to understand the current trends in prophylactic antibiotic use during ASD surgery through an international survey. MET ... Full text Open Access Link to item Cite

The ISSG-AO Complication Intervention Score, but Not Major/Minor Designation, is Correlated With Length of Stay Following Adult Spinal Deformity Surgery.

Journal Article Global Spine J · March 2025 STUDY DESIGN: Retrospective review. OBJECTIVES: The International Spine Study Group-AO (ISSG-AO) Adult Spinal Deformity (ASD) Complication Classification System was developed to improve classification, reporting, and study of complications among patients u ... Full text Open Access Link to item Cite

Adult Cervical Deformity Patients Have Higher Baseline Frailty, Disability, and Comorbidities Compared With Complex Adult Thoracolumbar Deformity Patients: A Comparative Cohort Study of 616 Patients.

Journal Article Global Spine J · March 2025 STUDY DESIGN: Multicenter comparative cohort. OBJECTIVE: Studies have shown markedly higher rates of complications and all-cause mortality following surgery for adult cervical deformity (ACD) compared with adult thoracolumbar deformity (ATLD), though the r ... Full text Open Access Link to item Cite

Alterations in Magnitude and Shape of Thoracic Kyphosis Following Surgical Correction for Adult Spinal Deformity.

Journal Article Global Spine J · March 2025 STUDY DESIGN: Retrospective review of prospective multicenter data. OBJECTIVES: This study aimed to investigate the shape of TK before and after fusion in ASD patients treated with long fusion. METHODS: ASD patients undergoing posterior spinal fusions incl ... Full text Open Access Link to item Cite

Cost Benefit of Implementation of Risk Stratification Models for Adult Spinal Deformity Surgery.

Journal Article Global Spine J · March 2025 STUDY DESIGN/SETTING: Retrospective cohort study. OBJECTIVE: Assess the extent to which defined risk factors of adverse events are drivers of cost-utility in spinal deformity (ASD) surgery. METHODS: ASD patients with 2-year (2Y) data were included. Tertile ... Full text Open Access Link to item Cite

Letter re: Incremental Increase in Hospital Length of Stay Due to Complications of Surgery for Adult Spinal Deformity.

Journal Article Global Spine J · March 2025 Full text Open Access Link to item Cite

The gap between surgeon goal and achieved sagittal alignment in adult cervical spine deformity surgery.

Journal Article J Neurosurg Spine · March 1, 2025 OBJECTIVE: Malalignment following cervical spine deformity (CSD) surgery can negatively impact outcomes and increase complications. Despite the growing ability to plan alignment, it remains unclear whether preoperative goals are achieved with surgery. The ... Full text Open Access Link to item Cite

Urinary control in cervical myelopathy: does it improve postsurgery? A Quality Outcomes Database study.

Journal Article J Neurosurg Spine · February 28, 2025 OBJECTIVE: Cervical spondylotic myelopathy (CSM) can be associated with urinary dysfunction, leading to an inability or marked difficulty with micturition. This study aimed to evaluate the urinary dysfunction, long-term prognosis, and recovery in patients ... Full text Open Access Link to item Cite

Iatrogenic posterior translation of the construct at the uppermost instrumented vertebrae is associated with proximal junctional kyphosis.

Journal Article Eur Spine J · February 17, 2025 PURPOSE: To determine if iatrogenic posterior translation (UIV SPi) at the upper instrumented vertebrae (UIV) is associated with increased mechanical complications and secondarily to generate and validate a UIV SPi threshold for increased complications. ME ... Full text Open Access Link to item Cite

Does smoking status affect baseline symptom severity and patient-reported outcomes and satisfaction in patients with cervical myelopathy at 24 months? A Quality Outcomes Database study.

Journal Article J Neurosurg Spine · February 14, 2025 OBJECTIVE: It is not clear whether smoking impacts patient-reported outcomes (PROs) in patients with cervical spondylotic myelopathy (CSM). The aim of this study was to explore the impact of smoking status on baseline symptom severity and the rate of achie ... Full text Open Access Link to item Cite

When is staging complex adult spinal deformity advantageous? Identifying subsets of patients who benefit from staged interventions.

Journal Article J Neurosurg Spine · February 1, 2025 OBJECTIVE: The objective of this study was to identify baseline patient and surgical factors predictive of optimal outcomes in staged versus same-day combined-approach surgery. METHODS: Adult spinal deformity (ASD) patients with baseline and perioperative ... Full text Open Access Link to item Cite

Fractional curve following adult idiopathic scoliosis correction: impact of curve magnitude on postoperative outcomes.

Journal Article J Neurosurg Spine · February 1, 2025 OBJECTIVE: The goal of this study was to assess the impact of fractional curve (FC) severity on curve progression and postoperative outcomes in patients undergoing adult idiopathic scoliosis (AdIS) correction. METHODS: Patients with AdIS who had preoperati ... Full text Open Access Link to item Cite

Assessing Abnormal Proximal Junctional Angles in Adult Spinal Deformity: A Normative Data Approach to Define Proximal Junctional Kyphosis.

Journal Article Spine (Phila Pa 1976) · January 15, 2025 STUDY DESIGN: Multicentric retrospective study of prospectively collected data. OBJECTIVE: On the basis of normative data from a cohort of asymptomatic volunteers, this study sought to determine the rate of abnormal values of proximal junctional angles (PJ ... Full text Open Access Link to item Cite

Patient-reported outcome trajectories the first 24 months after surgery for cervical spondylotic myelopathy: a Quality Outcomes Database study.

Journal Article J Neurosurg Spine · January 10, 2025 OBJECTIVE: Cervical spondylotic myelopathy (CSM) shows varying levels of improvement after surgical treatment. While some patients improve soon after surgery, others may take months to years to show any signs of improvement. The goal of this study was to e ... Full text Open Access Link to item Cite

Comparison of clinical and radiological outcomes of three-column lumbar osteotomies with and without interbody cages for adult spinal deformity.

Journal Article Spine J · January 10, 2025 BACKGROUND CONTEXT: Correcting sagittal malalignment in adult spinal deformity (ASD) is a challenging task, often requiring complex surgical interventions like pedicle subtraction osteotomies (PSOs). Different types of three-column osteotomies (3COs), incl ... Full text Open Access Link to item Cite

Wound Closure and Wound Dressings in Adult Spinal Deformity Surgery From the AO Spine Surveillance of Post-Operative Management

Journal Article Global Spine Journal · January 1, 2025 Study Design: An e-mail-based online survey for adult spinal deformity (ASD) surgeons. Objective: Wound closure and dressing techniques may vary according to the discretion of the surgeon as well as geographical location. However, there are no reports on m ... Full text Open Access Cite

Impact of Prior Cervical Fusion on Patients Undergoing Thoracolumbar Deformity Correction.

Journal Article Spine (Phila Pa 1976) · January 1, 2025 STUDY DESIGN: Retrospective analysis of prospectively collected data. OBJECTIVE: Evaluate the impact of prior cervical constructs on upper instrumented vertebrae (UIV) selection and postoperative outcomes among patients undergoing thoracolumbar deformity c ... Full text Open Access Link to item Cite

Intraoperative fluid management in adult spinal deformity surgery: variation analysis and association with outcomes.

Journal Article Spine Deform · January 2025 PURPOSE: To evaluate the variability in intraoperative fluid management during adult spinal deformity (ASD) surgery, and analyze the association with complications, intensive care unit (ICU) requirement, and length of hospital stay (LOS). METHODS: Multicen ... Full text Open Access Link to item Cite

Machine learning in the diagnosis, management, and care of patients with low back pain: a scoping review of the literature and future directions.

Journal Article Spine J · January 2025 BACKGROUND CONTEXT: Low back pain (LBP) remains the leading cause of disability globally. In recent years, machine learning (ML) has emerged as a potentially useful tool to aid the diagnosis, management, and prognostication of LBP. PURPOSE: In this review, ... Full text Open Access Link to item Cite

Incidence of revision surgery and patient-reported outcomes within 5 years of the index procedure for grade 1 spondylolisthesis: an analysis from the Quality Outcomes Database spondylolisthesis data.

Journal Article J Neurosurg Spine · January 1, 2025 OBJECTIVE: Some patients treated surgically for grade 1 spondylolisthesis require revision surgery. Outcomes after revision surgery are not well studied. The objective of this study was to determine how revision surgery impacts patient-reported outcomes (P ... Full text Open Access Link to item Cite

Which components of the global alignment proportionality score have the greatest impact on outcomes in adult spinal deformity corrective surgery?

Journal Article Eur Spine J · January 2025 PURPOSE: To investigate the impact of the Global Alignment and Proportion (GAP) score components on patient outcomes in Adult Spine Deformity (ASD) surgery. METHODS: Patients included underwent assessment via the GAP score and its individual components: pe ... Full text Open Access Link to item Cite

Proximal Lumbar Anterior Column Realignment for Iatrogenic Sagittal Plane Adult Spinal Deformity Correction: A Retrospective Case Series.

Journal Article World Neurosurg · January 2025 BACKGROUND: Anterior column realignment (ACR) is a powerful minimally invasive surgery technique to restore sagittal alignment in adult spinal deformity (ASD). This can accomplish similar segmental lordosis restoration as 3-column osteotomy with less blood ... Full text Open Access Link to item Cite

Long-term follow-up of non‑neurologic and neurologic complications after complex adult spinal deformity surgery: results from the Scoli-RISK-1 study

Journal Article European Spine Journal · January 1, 2025 Purpose: To report all complications that occurred during the 2 to 5-year postoperative period, describe reoperations during this time period, and compare patients who did and did not have major, surgery-related complications and/or reoperations during thi ... Full text Open Access Cite

Synthetic osteobiologics in spine surgery: A review

Journal Article Turkish Journal of Medical Sciences · January 1, 2025 Osteobiologics are increasingly used in orthopedics and spine surgery to facilitate bone healing and prevent nonunion. Synthetic osteobiologics are artificial materials crafted in laboratories that aim to replicate the natural composition and functionality ... Full text Open Access Cite

Cause and effect of revisions in adult spinal deformity surgery: a multicenter study on outcomes based on etiology.

Journal Article Spine J · December 18, 2024 BACKGROUND CONTEXT: While the treatment of adult spinal deformity (ASD) has increasingly favored surgical correction, the incidence of revision surgery remains high. Yet, little has been explored on the association between the etiology of reoperation and p ... Full text Open Access Link to item Cite

Comparative Analysis of Outcomes in Adult Spinal Deformity Patients with Proximal Junctional Kyphosis or Failure Initially Fused to Upper Versus Lower Thoracic Spine.

Journal Article J Clin Med · December 18, 2024 Background: Patients with proximal junctional kyphosis (PJK) or failure (PJF) may demonstrate disparate outcomes and recovery when fused to the upper (UT) versus lower (LT) thoracic spine. Few studies have distinguished the reoperation and recovery abiliti ... Full text Open Access Link to item Cite

The T4-L1-Hip Axis: Sagittal Spinal Realignment Targets in Long-Construct Adult Spinal Deformity Surgery: Early Impact.

Journal Article J Bone Joint Surg Am · December 4, 2024 BACKGROUND: Our understanding of the relationship between sagittal alignment and mechanical complications is evolving. In normal spines, the L1-pelvic angle (L1PA) accounts for the magnitude and distribution of lordosis and is strongly associated with pelv ... Full text Open Access Link to item Cite

High-Dose TXA Is Associated with Less Blood Loss Than Low-Dose TXA without Increased Complications in Patients with Complex Adult Spinal Deformity.

Journal Article J Bone Joint Surg Am · December 4, 2024 BACKGROUND: Tranexamic acid (TXA) is commonly utilized to reduce blood loss in adult spinal deformity (ASD) surgery. Despite its widespread use, there is a lack of consensus regarding the optimal dosing regimen. The aim of this study was to assess differen ... Full text Open Access Link to item Cite

Comparative analysis of patient-reported outcomes in myelopathy and myeloradiculopathy: a Quality Outcomes Database study.

Journal Article J Neurosurg Spine · December 1, 2024 OBJECTIVE: Myelopathy in the cervical spine can present with diverse symptoms, many of which can be debilitating for patients. Patients with radiculopathy symptoms demonstrate added complexity because of the overlapping symptoms and treatment consideration ... Full text Open Access Link to item Cite

Comparison of intraoperative and postoperative outcomes between open, wiltse, and percutaneous approach to traumatic thoracolumbar spine fractures without neurological injury: A systematic review and meta-analysis.

Journal Article N Am Spine Soc J · December 2024 BACKGROUND: Traumatic thoracolumbar fracture fixation without neurological injury can be performed using the traditional open, mini-open Wiltse, and percutaneous approaches. This systematic review and meta-analysis aims to compare perioperative outcomes be ... Full text Open Access Link to item Cite

Necessity of posterior osteotomies for mild flexible cervical deformity correction.

Journal Article J Neurosurg Spine · December 1, 2024 OBJECTIVE: Correction of mild flexible cervical deformity (CD) via the posterior approach has been described with and without the use of posterior osteotomies (POs), despite a lack of clarity regarding their necessity or risks. The purpose of this study wa ... Full text Open Access Link to item Cite

So Close yet So Far: The impact of undercorrection of cervical sagittal alignment during adult cervical deformity surgery - An Incremental correction analysis.

Journal Article J Clin Neurosci · December 2024 BACKGROUND: To compare degrees of cSVA correction and to theorize possible minimum and maximum thresholds of cSVA correction for patients to benefit clinically. METHODS: 657 operative ACD patients in a retrospective cohort study of a prospectively enrolled ... Full text Open Access Link to item Cite

Defining modern iatrogenic flatback syndrome: examination of segmental lordosis in short lumbar fusion patients undergoing thoracolumbar deformity correction.

Journal Article Eur Spine J · December 2024 PURPOSE: Understanding the mechanism and extent of preoperative deformity in revision procedures may provide data to prevent future failures in lumbar spinal fusion patients. METHODS: ASD patients without prior spine surgery (PRIMARY) and with prior short ... Full text Open Access Link to item Cite

Treatment of adult spine deformity: A retrospective comparison of bone morphogenic protein and bone marrow aspirate with bone allograft.

Journal Article Acta Neurochir (Wien) · November 11, 2024 UNLABELLED: BACKGROUND : The use of bone morphogenic protein (BMP-2) in adult spine deformity (ASD) surgery remains controversial more than two decades following its approval for clinical application in spine surgery. This study was performed to assess ou ... Full text Open Access Link to item Cite

Prevalence and Prognosis of Coronal Malalignment Following Lateral Lumbar Interbody Fusion for Minimally Invasive Treatment of Adult Spinal Deformity.

Journal Article Spine (Phila Pa 1976) · November 7, 2024 STUDY DESIGN: Retrospective analysis of prospective multicenter adult spinal deformity (ASD) database. OBJECTIVE: To determine the prevalence and prognosis of postoperative coronal malalignment following LLIF for ASD with Qiu type A coronal alignment. SUMM ... Full text Open Access Link to item Cite

Impact of Knee Osteoarthritis and Arthroplasty on Full Body Sagittal Alignment in Adult Spinal Deformity Patients.

Journal Article Spine (Phila Pa 1976) · November 6, 2024 STUDY DESIGN: Retrospective analysis of prospectively collected data. OBJECTIVE: This study evaluates the impact of knee osteoarthritis (OA) and knee arthroplasty on alignments and patient-reported outcomes measures (PROMS) of patients undergoing adult spi ... Full text Open Access Link to item Cite

Have We Made Advancements in Optimizing Surgical Outcomes and Enhancing Recovery for Patients With High-Risk Adult Spinal Deformity Over Time?

Journal Article Oper Neurosurg (Hagerstown) · November 4, 2024 BACKGROUND AND OBJECTIVES: The spectrum of patients requiring adult spinal deformity (ASD) surgery is highly variable in baseline (BL) risk such as age, frailty, and deformity severity. Although improvements have been realized in ASD surgery over the past ... Full text Open Access Link to item Cite

Independent Prognostic Factors Associated With Improved Patient-Reported Outcomes in the Prospective Evaluation of Elderly Deformity Surgery (PEEDS) Study.

Journal Article Global Spine J · November 2024 STUDY DESIGN: Prospective, multicenter, international, observational study. OBJECTIVE: Identify independent prognostic factors associated with achieving the minimal clinically important difference (MCID) in patient reported outcome measures (PROMs) among a ... Full text Open Access Link to item Cite

The Incremental Clinical Benefit of Adding Layers of Complexity to the Planning and Execution of Adult Spinal Deformity Corrective Surgery.

Journal Article Oper Neurosurg (Hagerstown) · November 1, 2024 BACKGROUND AND OBJECTIVES: For patients with surgical adult spinal deformity (ASD), our understanding of alignment has evolved, especially in the last 20 years. Determination of optimal restoration of alignment and spinal shape has been increasingly studie ... Full text Open Access Link to item Cite

Contemporary utilization of three-column osteotomy techniques in a prospective complex spinal deformity multicenter database: implications on full-body alignment and perioperative course.

Journal Article Spine Deform · November 2024 BACKGROUND: Research has focused on the increased correction from a three-column osteotomy (3CO) during adult spinal deformity (ASD) surgery. However, an in-depth analysis on the performance of a 3CO in a cohort of complex spinal deformity cases has not be ... Full text Open Access Link to item Cite

Thoracolumbar fusions for adult lumbar deformity show superior QALY gain and lower costs compared with upper thoracic fusions.

Journal Article Spine Deform · November 2024 PURPOSE: Adult spinal deformity (ASD) patients with sagittal plane deformity (N) or structural lumbar/thoraco-lumbar (TL) curves can be treated with fusions stopping at the TL junction or extending to the upper thoracic (UT) spine. This study evaluates the ... Full text Open Access Link to item Cite

Cost-effectiveness of posterior lumbar interbody fusion and/or transforaminal lumbar interbody fusion for grade 1 lumbar spondylolisthesis: a 5-year Quality Outcomes Database study.

Journal Article J Neurosurg Spine · November 1, 2024 OBJECTIVE: Posterior lumbar interbody fusion (PLIF) and/or transforaminal lumbar interbody fusion (TLIF), referred to as "PLIF/TLIF," is a commonly performed operation for lumbar spondylolisthesis. Its long-term cost-effectiveness has not been well describ ... Full text Open Access Link to item Cite

Predictors of patient satisfaction in the surgical treatment of cervical spondylotic myelopathy.

Journal Article J Neurosurg Spine · November 1, 2024 OBJECTIVE: Patients with cervical spondylotic myelopathy (CSM) experience progressive neurological impairment. Surgical intervention is often pursued to halt neurological symptom progression and allow for recovery of function. In this paper, the authors ex ... Full text Open Access Link to item Cite

Predictors of patient satisfaction after surgery for grade 1 degenerative spondylolisthesis: a 5-year analysis of the Quality Outcomes Database.

Journal Article J Neurosurg Spine · November 1, 2024 OBJECTIVE: Lumbar decompression and/or fusion surgery is a common operation for symptomatic lumbar spondylolisthesis refractory to conservative management. Multiyear follow-up of patient outcomes can be difficult to obtain but allows for identification of ... Full text Open Access Link to item Cite

Do obese patients undergoing surgery for grade 1 spondylolisthesis have worse outcomes at 5 years' follow-up? A QOD study.

Journal Article J Neurosurg Spine · November 1, 2024 OBJECTIVE: The long-term effects of increased body mass index (BMI) on surgical outcomes are unknown for patients who undergo surgery for low-grade lumbar spondylolisthesis. The goal of this study was to assess long-term outcomes in obese versus nonobese p ... Full text Open Access Link to item Cite

Do class III obese patients achieve similar outcomes and satisfaction to nonobese patients following surgery for cervical myelopathy? A QOD study.

Journal Article J Neurosurg Spine · November 1, 2024 OBJECTIVE: The aim of this study was to compare the rate of achievement of the minimal clinically important difference (MCID) in patient-reported outcomes (PROs) and satisfaction between cervical spondylotic myelopathy (CSM) patients with and without class ... Full text Open Access Link to item Cite

Does comorbid depression and anxiety portend poor long-term outcomes following surgery for lumbar spondylolisthesis? Five-year analysis of the Quality Outcomes Database.

Journal Article J Neurosurg Spine · November 1, 2024 OBJECTIVE: Depression and anxiety are associated with poor outcomes following spine surgery. However, the influence of these conditions on achieving a minimal clinically important difference (MCID) following lumbar spine surgery, as well as the potential c ... Full text Open Access Link to item Cite

Frail patients require instrumentation of a more proximal vertebra for a successful outcome after surgery for adult spine deformity.

Journal Article Bone Joint J · November 1, 2024 AIMS: The aim of this study was to investigate the impact of the level of upper instrumented vertebra (UIV) in frail patients undergoing surgery for adult spine deformity (ASD). METHODS: Patients with adult spinal deformity who had undergone T9-to-pelvis f ... Full text Open Access Link to item Cite

Unsupervised Clustering of Adult Spinal Deformity Patterns Predicts Surgical and Patient-Reported Outcomes.

Journal Article Global Spine J · October 23, 2024 STUDY DESIGN: Retrospective cohort study. OBJECTIVES: To evaluate whether different radiographic clusters of adult spinal deformity identified using artificial intelligence-based clustering are associated with distinct surgical outcomes. METHODS: Patients ... Full text Open Access Link to item Cite

Factors Associated With the Maintenance of Cost-effectiveness at Five Years in Adult Spinal Deformity Corrective Surgery.

Journal Article Spine (Phila Pa 1976) · October 15, 2024 STUDY DESIGN: Retrospective cohort. OBJECTIVE: To evaluate factors associated with the long-term durability of cost-effectiveness (CE) in ASD patients. BACKGROUND: A substantial increase in costs associated with the surgical treatment for adult spinal defo ... Full text Open Access Link to item Cite

Postoperative C5 Palsy after Anterior or Posterior Decompression for Degenerative Cervical Myelopathy: A Subgroup Analysis of the Multicenter, Prospective, Randomized, Phase III, CSM-Protect Clinical Trial.

Journal Article Spine (Phila Pa 1976) · October 15, 2024 STUDY DESIGN: Retrospective cohort study of prospectively accrued data. OBJECTIVE: To evaluate a large, prospective, multicentre dataset of surgically treated degenerative cervical myelopathy (DCM) cases on the contemporary risk of C5 palsy with surgical a ... Full text Open Access Link to item Cite

Cost-effectiveness Improves for Operative vs Nonoperative Treatment of Adult Symptomatic Lumbar Scoliosis at Eight-Year Follow-up.

Journal Article Spine (Phila Pa 1976) · October 14, 2024 STUDY DESIGN: Secondary data analysis of the NIH sponsored study on Adult Symptomatic Lumbar Scoliosis (ASLS). OBJECTIVES: The purpose of this study is to perform a cost-effectiveness analysis comparing operative versus non-operative care for ASLS eight ye ... Full text Open Access Link to item Cite

Mechanisms of lumbar spine "flattening" in adult spinal deformity: defining changes in shape that occur relative to a normative population.

Journal Article Eur Spine J · October 2024 PURPOSE: Previous work comparing ASD to a normative population demonstrated that a large proportion of lumbar lordosis is lost proximally (L1-L4). The current study expands on these findings by collectively investigating regional angles and spinal contours ... Full text Open Access Link to item Cite

The Conceptualization and Derivation of the Cervical Lordosis Distribution Index.

Journal Article Spine (Phila Pa 1976) · September 30, 2024 SUMMARY OF BACKGROUND DATA: Yilgor et al developed the lumbar Lordosis Distribution Index to individualize the pelvic mismatch to each patient's pelvic incidence. The cervical lordosis distribution in relation to its apex has not been characterized. OBJECT ... Full text Open Access Link to item Cite

Benchmark Values for Construct Survival and Complications by Type of ASD Surgery.

Journal Article Spine (Phila Pa 1976) · September 15, 2024 OBJECTIVE: The aim of this study was to provide benchmarks for the rates of complications by type of surgery performed. STUDY DESIGN: Prospective multicenter database. BACKGROUND: We have previously examined overall construct survival and complication rate ... Full text Open Access Link to item Cite

Incremental Increase in Hospital Length of Stay Due to Complications of Surgery for Adult Spinal Deformity.

Journal Article Global Spine J · September 5, 2024 STUDY DESIGN: Retrospective Cohort Study. OBJECTIVES: Length of Stay (LOS) and resource utilization are of primary importance for hospital administration. This study aimed to understand the incremental effect of having a specific complication on LOS among ... Full text Open Access Link to item Cite

How Good Are Surgeons at Achieving Their Preoperative Goal Sagittal Alignment Following Adult Deformity Surgery?

Journal Article Global Spine J · September 2024 STUDY DESIGN: Multicenter, prospective cohort. OBJECTIVES: Malalignment following adult spine deformity (ASD) surgery can impact outcomes and increase mechanical complications. We assess whether preoperative goals for sagittal alignment following ASD surge ... Full text Open Access Link to item Cite

The Influence of Multilevel Spinal Deformity Surgery on the EuroQol 5 Dimensions' (EQ-5D) Questionnaire and Residential Status in the Elderly: A Prospective, Observational, Multicenter Study.

Journal Article Global Spine J · September 2024 STUDY DESIGN: Multicenter, international prospective study. OBJECTIVE: This study investigated the clinical outcome up to 2 years after multi-level spinal deformity surgery in the elderly by reporting the minimal clinically important difference (MCID) of E ... Full text Open Access Link to item Cite

Lumbar Lordosis Redistribution and Segmental Correction in Adult Spinal Deformity: Does it Matter?

Journal Article Spine (Phila Pa 1976) · September 1, 2024 STUDY DESIGN: Retrospective analysis of prospectively collected data. OBJECTIVE: Evaluate the impact of correcting normative segmental lordosis values on postoperative outcomes. BACKGROUND: Restoring lumbar lordosis magnitude is crucial in adult spinal def ... Full text Open Access Link to item Cite

Impact of educational background on preoperative disease severity and postoperative outcomes among patients with lumbar spondylolisthesis: a Quality Outcomes Database study.

Journal Article J Neurosurg Spine · September 1, 2024 OBJECTIVE: Deficiency in patient education has been correlated with increased disease-related morbidity and decreased access to care. However, the associations between educational level, preoperative disease severity, and postoperative outcomes in patients ... Full text Open Access Link to item Cite

Restoring L4-S1 Lordosis Shape in Severe Sagittal Deformity: Impact of Correction Techniques on Alignment and Complication Profile.

Journal Article World Neurosurg · September 2024 BACKGROUND: Severe sagittal plane deformity with loss of L4-S1 lordosis is disabling and can be improved through various surgical techniques. However, data are limited on the differing ability of anterior lumbar interbody fusion (ALIF), pedicle subtraction ... Full text Open Access Link to item Cite

Shifting Trends in the Epidemiology of Cervical Spine Injuries: An Analysis of 11,822 Patients from the National Electronic Injury Surveillance System over Two Decades.

Journal Article J Neurotrauma · September 2024 Cervical spine injuries (CSIs) are heterogeneous in nature and often lead to long-term disability and morbidity. However, there are few recent and comprehensive epidemiological studies on CSI. The objective of this study was to characterize recent trends i ... Full text Open Access Link to item Cite

Expectations of clinical improvement following corrective surgery for adult cervical deformity based on functional disability at presentation.

Journal Article Spine Deform · September 2024 PURPOSE: To assess impact of baseline disability on HRQL outcomes. METHODS: CD patients with baseline (BL) and 2 year (2Y) data included, and ranked into quartiles by baseline NDI, from lowest/best score (Q1) to highest/worst score (Q4). Means comparison t ... Full text Open Access Link to item Cite

Contemporary guidelines for acetabular positioning in hip arthroplasty may jeopardize hip dislocation for select ASD patients

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Lewinnek et al previously defined a safe zone for cup inclination (40° ± 10°) and anteversion (15° ± 10°) to reduce dislocations after total hip arthroplasty (THA). Despite the Lewinnek safe zone being respected, higher rates of prosthe ... Full text Cite

Who are super-utilizers in adult spine deformity surgery and how can surgeons identify them preoperatively?

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: A relatively small percentage of patients are responsible for a disproportional amount of resource utilization in adult ASD surgery and contribute to significantly elevating the average cost across the surgically treated patients. These ... Full text Open Access Cite

Three-dimensional evaluation of the dynamic interplay between pelvic anatomy, lower-limb compensation, and standing alignment in ASD

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Previous studies have shown that lower limbs play a crucial role in compensating for sagittal spinal malalignment. However, these studies primarily focused on lower limb parameters in the sagittal plane, mainly knee flexion, leaving com ... Full text Open Access Cite

Quantifying the importance of upper cervical extension reserve in adult cervical deformity surgery and its impact on baseline presentation and outcomes

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Hyperextension of the upper cervical spine is a prominent compensatory mechanism to maintain horizontal gaze and balance in adult cervical deformity (ACD) patients, akin to pelvic tilt in spinal deformity. The relaxation of ER and its i ... Full text Open Access Cite

Medicare's benchmarking spinal DRGs have limited utility in capturing key quality metrics for adult spinal deformity (ASD)

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Heterogeneity of adult spinal deformity (ASD) and associated surgical options call into question Medicare's spinal-deformity-specific diagnosis-related group (DRG) to accurately capture nuances of episodes of care associated with ASD op ... Full text Cite

Does coronal plane deformity matter for cervicothoracic kyphosis surgery? The incidence of cervical scoliosis and influence on the outcomes of cervical deformity surgery

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Cervical deformity (CD) patients may have both cervical kyphosis (CK) and coronal plane cervical deformity, ie, cervical scoliosis (CS). Although the deformity with the greatest influence on the clinical outcomes is CK, few studies have ... Full text Cite

Late to extubate? Risk factors & associations for delayed extubation after adult cervical deformity

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Due to the proximity of the surgical site to important respiratory and oropharyngeal structures, patients may undergo delayed extubation after adult cervical deformity (ACD) surgery to manage postoperative airway edema/obstruction and r ... Full text Cite

Factors associated with timing for revision surgery for proximal junctional kyphosis (PJK)

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Proximal junctional kyphosis (PJK) is a radiographic complication following adult spinal deformity (ASD) surgery. The decision-making process for PJK revision surgery is multi-faceted, involving the evaluation of clinical symptoms, radi ... Full text Cite

Comparison of elderly patients with spinal deformity fused from the upper versus the lower thoracic/thoracolumbar spine to the sacrum. Prospective evaluation of elderly deformity surgery (PEEDS) study

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: In adult spinal deformity (ASD) surgery, choosing the upper instrumented vertebra (UIV) between the upper thoracic (UT) or lower thoracic/thoracolumbar (LT) spine is critical to balancing the risk of perioperative surgical morbidity wit ... Full text Cite

Opportunistic tool for immediate assessment of bone mineral density

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: While the role of several spinal radiographic measurements on patients’ spinal health, surgical planning, and outcome prediction has been investigated, the role of BMD values in treatment of spinal condition is not well documented. A hi ... Full text Cite

Fractional curve behavior following adult idiopathic scoliosis correction

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Despite being a potential common cause of poor functional outcomes, few studies have assessed lumbosacral fractional curves (FC) behavior in adults. In particular, little is known about the temporal progression of FC in adults undergoin ... Full text Cite

Analysis of success versus failed realignment in patients with cervical deformity: in-construct angles provide novel targets for correction

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Correction of cervical deformity (CD) has the potential to improve patient function significantly. However, previously described radiographic parameters cannot be measured intraoperatively. The present study investigates in-construct me ... Full text Cite

The cervical lordosis distribution index and its consideration of upper cervical region and morphology

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: The cervical lordosis distribution in relation to its apex has not been characterized, nor has the impact of morphologic differences and upper cervical segments. PURPOSE: The goal of this study is assess whether tailored correction of c ... Full text Open Access Cite

Do interbody devices that traverse the lumbar apex result in improved outcomes and alignment in adult spinal deformity

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Interbody devices (IBD) are commonly used to correct deformity and are more often employed distally at the lumbosacral junction. Assessment of the impact on alignment and outcomes for IBD placed distal to the lumbar lordosis apex relati ... Full text Cite

Selection of upper instrumented vertebra in adult spinal deformity: risk calculator and recommendations based on proximal junctional kyphosis

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: The surgical correction of adult spinal deformity (ASD) presents a complex and multifaceted challenge, further intensified by the need for revision surgery. Determination of the upper instrumented vertebra can often be challenging. PURP ... Full text Open Access Cite

Contemporary treatment of complex adult spine deformity using bone morphogenic protein: a comparative analysis of outcome and complication profiles

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: There is controversy surrounding the use of bone morphogenic protein (BMP-2) in spine surgery with multiple off-label uses. The widespread use of BMP-2 is spine deformity surgery remains unsupported by literature. PURPOSE: To assess out ... Full text Cite

Sarcopenic obesity: an underrated phenomenon impacting adult spinal deformity intervention outcomes

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: The amount and quality of tissue do not always positively correlate as is the case with sarcopenic obesity. As the population of elderly people with adult spinal deformity (ASD) continues to increase, sarcopenia (decreased muscle mass) ... Full text Open Access Cite

Severe hip and knee osteoarthritis worsens patient-reported disability in adult spinal deformity patients

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: The complex interplay between lower extremity osteoarthritis and sagittal alignment in adult spinal deformity patients is of growing clinical interest. PURPOSE: To quantify the sequential effects of lower extremity OA on PROMs in ASD pa ... Full text Open Access Cite

A hard pill to swallow: factors associated with dysphagia following adult cervical deformity surgery

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Dysphagia has long been intertwined with cervical interventions and significantly impacts patients’ quality of life. Still, the development and evolution of dysphagia is difficult to predict. PURPOSE: To discern which factors affect the ... Full text Cite

Preoperative dysphonia and dysphagia improve following cervical deformity surgery

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Twenty-five percent of adult cervical deformity patients undergoing deformity correction have impairment due to a voice problem prior to surgery. Prior work has shown that these patients tend to be more frail and more likely to report p ... Full text Open Access Cite

Clinical and Patient-Reported Outcomes of Adult Spinal Deformity Surgery with 10-Year Follow-Up

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Adult spinal deformity (ASD) has been demonstrated to negatively influence patients’ physical and mental health. Yet, previous literature has described that ASD corrective surgery to significantly improve patients’ quality of life and r ... Full text Cite

Optimizing surgical timing: evaluating disability, frailty, and deformity severity thresholds in adult spinal deformity

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Adult spinal deformity is a complex condition with a challenging demographic that often has high frailty, disability, and deformity at the time of surgical correction. Thresholds at which there is a point of diminishing returns can help ... Full text Cite

Cost-benefit of Enhanced Recovery After Surgery protocols in adult spine deformity surgery

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Enhanced Recovery After Surgery (ERAS) has been shown to accelerate patient recovery while reducing costs and maintaining high-quality patient care. The long-term effects after implementation in adult spine deformity (ASD) patients rema ... Full text Cite

Proximal junctional kyphosis and failure: How much can we attribute to known risk factors?

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Despite advancements in the understanding of spinal alignment and in instrumentation for adult spine deformity (ASD) surgery, complications such as proximal junctional kyphosis and proximal junctional failure (PJK/PJF) continue to be a ... Full text Open Access Cite

Interbody device placement in thoracolumbar scoliosis malalignment affects mechanical complications and outcomes

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Focal coronal malalignment in the lower lumbar spine can place significant forces on the construct and can be a challenge to correct. The use of supplemental rods and interbody devices (IBD) can potentially reduce rates of mechanical fa ... Full text Cite

Optimal octogenarians: which elderly patients best tolerate adult spinal deformity corrective surgery?

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Intervention for adult spinal deformity (ASD) can be invasive, and often as patients age, they are more susceptible to the physiological burden imposed by such extensive surgeries. Still studies have proven that rigorous realignment is ... Full text Cite

The dreaded false negatives – when intraoperative neuromonitoring fails to detect neural deficits associated with complex, noncord-level spinal deformity corrections

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Preservation of postoperative neural function is necessary to the success of operations to address spinal deformity. PURPOSE: To evaluate rates of new neural deficits relative to intraoperative neuromonitoring (IONM) alerts in noncord-l ... Full text Cite

Impact of Enhanced Recovery After Surgery (ERAS) protocols in adult spinal deformity corrective surgery utilizing three-column osteotomies

Conference Spine Journal · September 1, 2024 BACKGROUND CONTEXT: Spine surgery for ASD is often highly invasive, especially when requiring three column osteotomies, that can often coincide with a prolonged recovery phase. These patients might benefit from ERAS, an evidence-based multidisciplinary app ... Full text Cite

Spinal cord injury in high-risk complex adult spinal deformity surgery: review of incidence and outcomes from the Scoli-RISK-1 study.

Journal Article Spinal Cord Ser Cases · August 17, 2024 STUDY DESIGN: Clinical case series. OBJECTIVE: To describe the cause, treatment and outcome of 6 cases of perioperative spinal cord injury (SCI) in high-risk adult deformity surgery. SETTING: Adult spinal deformity patients were enrolled in the multi-cente ... Full text Open Access Link to item Cite

The Importance of Planning Ahead: A Three-Dimensional Analysis of the Novel Trans-Facet Corridor for Posterior Lumbar Interbody Fusion Using Segmentation Technology.

Journal Article World Neurosurg · August 2024 BACKGROUND: The rise of minimally invasive lumbar fusions and advanced imaging technologies has facilitated the introduction of novel surgical techniques with the trans-facet approach being one of the newest additions. We aimed to quantify any pathology-dr ... Full text Open Access Link to item Cite

Predictors of Delayed Clinical Benefit Following Surgical Treatment for Low Grade Spondylolisthesis.

Journal Article Spine (Phila Pa 1976) · August 1, 2024 STUDY DESIGN: Retrospective review of prospectively collected data. OBJECTIVE: To investigate what factors predict delayed improvement after surgical treatment of low grade spondylolisthesis. SUMMARY OF BACKGROUND DATA: Lumbar surgery leads to clinical imp ... Full text Open Access Link to item Cite

Social determinants of health and disparities in spine surgery: a 10-year analysis of 8,565 cases using ensemble machine learning and multilayer perceptron.

Journal Article Spine J · July 20, 2024 BACKGROUND CONTEXT: The influence of SDOH on spine surgery is poorly understood. Historically, researchers commonly focused on the isolated influences of race, insurance status, or income on healthcare outcomes. However, analysis of SDOH is becoming increa ... Full text Open Access Link to item Cite

Hip Osteoarthritis in Patients Undergoing Surgery for Severe Adult Spinal Deformity: Prevalence and Impact on Spine Surgery Outcomes.

Journal Article J Bone Joint Surg Am · July 3, 2024 BACKGROUND: Hip osteoarthritis (OA) is common in patients with adult spinal deformity (ASD). Limited data exist on the prevalence of hip OA in patients with ASD, or on its impact on baseline and postoperative alignment and patient-reported outcome measures ... Full text Open Access Link to item Cite

Critical Analysis of Radiographic and Patient-Reported Outcomes Following Anterior/Posterior Staged Versus Same-Day Surgery in Patients Undergoing Identical Corrective Surgery for Adult Spinal Deformity.

Journal Article Spine (Phila Pa 1976) · July 1, 2024 STUDY DESIGN: A retrospective cohort study of a prospectively collected multicenter adult spinal deformity (ASD) database. OBJECTIVE: The aim of this study was to compare staged procedures to same-day interventions and identify the optimal time interval be ... Full text Open Access Link to item Cite

Using Novel Segmentation Technology to Define Safe Corridors for Minimally Invasive Posterior Lumbar Interbody Fusion.

Journal Article Oper Neurosurg (Hagerstown) · July 1, 2024 BACKGROUND AND OBJECTIVES: There has been a rise in minimally invasive methods to access the intervertebral disk space posteriorly given their decreased tissue destruction, lower blood loss, and earlier return to work. Two such options include the percutan ... Full text Open Access Link to item Cite

Comparing posterior cervical foraminotomy with anterior cervical discectomy and fusion in radiculopathic patients: an analysis from the Quality Outcomes Database.

Conference J Neurosurg Spine · July 1, 2024 OBJECTIVE: The objective of this study was to compare clinical and patient-reported outcomes (PROs) between posterior foraminotomy and anterior cervical discectomy and fusion (ACDF) in patients presenting with cervical radiculopathy. METHODS: The Quality O ... Full text Link to item Cite

Randomized Trial of Augmented Pelvic Fixation in Patients Undergoing Thoracolumbar Fusion for Adult Spine Deformity: Initial Results from a Multicenter Randomized Trial.

Journal Article World Neurosurg · July 2024 BACKGROUND: The optimal configuration for spinopelvic fixation during multilevel spine fusion surgery for adult spine deformity remains unclear. Postoperative sacroiliac (SI) joint pain, S2AI screw loosening and implant breakage could be related to continu ... Full text Open Access Link to item Cite

Complication Rates Following Adult Spinal Deformity Surgery: Evaluation of the Category of Complication and Chronology.

Journal Article Spine (Phila Pa 1976) · June 15, 2024 OBJECTIVE: Provide benchmarks for the rates of complications by type and timing. STUDY DESIGN: Prospective multicenter database. BACKGROUND: Complication rates following adult spinal deformity (ASD) surgery have been previously reported. However, the inter ... Full text Open Access Link to item Cite

Opioid Use Prior to Adult Spine Deformity Correction Surgery is Associated With Worse Pre- and Postoperative Back Pain and Prolonged Opioid Demands.

Journal Article Global Spine J · June 4, 2024 STUDY DESIGN: Prospective multicenter database post-hoc analysis. OBJECTIVES: Opioids are frequently prescribed for painful spinal conditions to provide pain relief and to allow for functional improvement, both before and after spine surgery. Amidst a curr ... Full text Open Access Link to item Cite

Riluzole for Degenerative Cervical Myelopathy: A Secondary Analysis of the CSM-PROTECT Trial.

Journal Article JAMA Netw Open · June 3, 2024 IMPORTANCE: The modified Japanese Orthopaedic Association (mJOA) scale is the most common scale used to represent outcomes of degenerative cervical myelopathy (DCM); however, it lacks consideration for neck pain scores and neglects the multidimensional asp ... Full text Open Access Link to item Cite

The Shape of the Fused Spine is Associated With Acute Proximal Junctional Kyphosis in Adult Spinal Deformity: An Assessment Based on Vertebral Pelvic Angles.

Journal Article Global Spine J · June 2024 STUDY DESIGN: Retrospective review of prospective database. OBJECTIVES: Vertebral pelvic angles (VPAs) account for complexity in spine shape by assessing the relative position of each vertebra with regard to the pelvis. This study uses VPAs to investigate ... Full text Open Access Link to item Cite

Impact of Hip and Knee Osteoarthritis on Full Body Sagittal Alignment and Compensation for Sagittal Spinal Deformity.

Journal Article Spine (Phila Pa 1976) · June 1, 2024 STUDY DESIGN: Retrospective review of prospectively collected data. OBJECTIVE: To investigate the effect of lower extremity osteoarthritis on sagittal alignment and compensatory mechanisms in adult spinal deformity (ASD). BACKGROUND: Spine, hip, and knee p ... Full text Open Access Link to item Cite

Machine learning clustering of adult spinal deformity patients identifies four prognostic phenotypes: a multicenter prospective cohort analysis with single surgeon external validation.

Journal Article Spine J · June 2024 BACKGROUND CONTEXT: Among adult spinal deformity (ASD) patients, heterogeneity in patient pathology, surgical expectations, baseline impairments, and frailty complicates comparisons in clinical outcomes and research. This study aims to qualitatively segmen ... Full text Open Access Link to item Cite

Stronger association of objective physical metrics with baseline patient-reported outcome measures than preoperative standing sagittal parameters for adult spinal deformity patients.

Journal Article J Neurosurg Spine · June 1, 2024 OBJECTIVE: Sagittal alignment measured on standing radiography remains a fundamental component of surgical planning for adult spinal deformity (ASD). However, the relationship between classic sagittal alignment parameters and objective metrics, such as wal ... Full text Open Access Link to item Cite

Analysis of tranexamic acid usage in adult spinal deformity patients with relative contraindications: does it increase the risk of complications?

Journal Article J Neurosurg Spine · June 1, 2024 OBJECTIVE: Complex spinal deformity surgeries may involve significant blood loss. The use of antifibrinolytic agents such as tranexamic acid (TXA) has been proven to reduce perioperative blood loss. However, for patients with a history of thromboembolic ev ... Full text Open Access Link to item Cite

Validation of the Oswestry Disability Index in Adult Spinal Deformity.

Journal Article Spine (Phila Pa 1976) · May 15, 2024 STUDY DESIGN: Retrospective cohort. OBJECTIVE: To examine the validity of the Oswestry Disability Index (ODI) in patients with adult spinal deformity (ASD) treated with surgery. BACKGROUND: The ODI is a patient-reported outcome measure of low back pain and ... Full text Open Access Link to item Cite

Revision Strategy for Proximal Junctional Failure: Combined Effect of Proximal Extension and Focal Correction.

Journal Article Global Spine J · May 12, 2024 STUDY DESIGN: Retrospective review of a prospectively-collected multicenter database. OBJECTIVES: The objective of this study was to determine optimal strategies in terms of focal angular correction and length of proximal extension during revision for PJF. ... Full text Open Access Link to item Cite

Postoperative Discharge to Acute Rehabilitation or Skilled Nursing Facility Compared With Home Does Not Reduce Hospital Readmissions, Return to Surgery, or Improve Outcomes Following Adult Spine Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · May 1, 2024 STUDY DESIGN: Retrospective review of a prospective multicenter adult spinal deformity (ASD) study. OBJECTIVE: The aim of this study was to evaluate 30-day readmissions, 90-day return to surgery, postoperative complications, and patient-reported outcomes ( ... Full text Open Access Link to item Cite

Development of a modified frailty index for adult spinal deformities independent of functional changes following surgical correction: a true baseline risk assessment tool.

Journal Article Spine Deform · May 2024 PURPOSE: To develop a simplified, modified frailty index for adult spinal deformity (ASD) patients dependent on objective clinical factors. METHODS: ASD patients with baseline (BL) and 2-year (2Y) follow-up were included. Factors with the largest R2 value ... Full text Open Access Link to item Cite

Cervical spondylotic myelopathy and driving abilities: defining the prevalence and long-term postoperative outcomes using the Quality Outcomes Database.

Journal Article J Neurosurg Spine · May 1, 2024 OBJECTIVE: Cervical spondylotic myelopathy (CSM) can cause significant difficulty with driving and a subsequent reduction in an individual's quality of life due to neurological deterioration. The positive impact of surgery on postoperative patient-reported ... Full text Open Access Link to item Cite

What is the effect of preoperative depression on outcomes after minimally invasive surgery for adult spinal deformity? A prospective cohort analysis.

Journal Article J Neurosurg Spine · May 1, 2024 OBJECTIVE: Depression has been implicated with worse immediate postoperative outcomes in adult spinal deformity (ASD) correction, yet the specific impact of depression on those patients undergoing minimally invasive surgery (MIS) requires further clarity. ... Full text Open Access Link to item Cite

Is Upper Extremity or Lower Extremity Function More Important for Patient Satisfaction? An Analysis of 24-Month Outcomes from the QOD Cervical Spondylotic Myelopathy Cohort.

Journal Article Clin Spine Surg · May 1, 2024 STUDY DESIGN: Retrospective analysis of a prospective, multicenter registry. OBJECTIVE: To assess whether upper or lower limb mJOA improvement more strongly associates with patient satisfaction after surgery for cervical spondylotic myelopathy (CSM). SUMMA ... Full text Open Access Link to item Cite

Are insufficient corrections a major factor in distal junctional kyphosis? A simulated analysis of cervical deformity correction using in-construct measurements.

Journal Article J Neurosurg Spine · May 1, 2024 OBJECTIVE: The present study utilized recently developed in-construct measurements in simulations of cervical deformity surgery in order to assess undercorrection and predict distal junctional kyphosis (DJK). METHODS: A retrospective review of a database o ... Full text Open Access Link to item Cite

Pushing the Limits of Minimally Invasive Spine Surgery-From Preoperative to Intraoperative to Postoperative Management.

Journal Article J Clin Med · April 20, 2024 The introduction of minimally invasive surgery ushered in a new era of spine surgery by minimizing the undue iatrogenic injury, recovery time, and blood loss, among other complications, of traditional open procedures. Over time, technological advancements ... Full text Open Access Link to item Cite

Early Experience with Prone Lateral Interbody Fusion in Deformity Correction: A Single-Institution Experience.

Journal Article J Clin Med · April 15, 2024 Background/Objectives: Lateral spine surgery offers effective minimally invasive deformity correction, but traditional approaches often involve separate anterior, lateral, and posterior procedures. The prone lateral technique streamlines this process by al ... Full text Open Access Link to item Cite

Evolution of the Transforaminal Lumbar Interbody Fusion (TLIF): From Open to Percutaneous to Patient-Specific.

Journal Article J Clin Med · April 14, 2024 The transforaminal lumbar interbody fusion (TLIF) has seen significant evolution since its early inception, reflecting advancements in surgical techniques, patient safety, and outcomes. Originally described as an improvement over the posterior lumbar inter ... Full text Open Access Link to item Cite

Impact of Self-Reported Loss of Balance and Gait Disturbance on Outcomes following Adult Spinal Deformity Surgery.

Journal Article J Clin Med · April 11, 2024 Background: The objective of this study was to evaluate if imbalance influences complication rates, radiological outcomes, and patient-reported outcomes (PROMs) following adult spinal deformity (ASD) surgery. Methods: ASD patients with baseline and 2-year ... Full text Open Access Link to item Cite

Impact of Educational Background on Preoperative Disease Severity and Postoperative Outcomes Among Patients With Cervical Spondylotic Myelopathy.

Journal Article Clin Spine Surg · April 1, 2024 STUDY DESIGN: Retrospective review of a prospectively maintained database. OBJECTIVE: Assess differences in preoperative status and postoperative outcomes among patients of different educational backgrounds undergoing surgical management of cervical spondy ... Full text Open Access Link to item Cite

What predicts the best 24-month outcomes following surgery for cervical spondylotic myelopathy? A QOD prospective registry study.

Journal Article J Neurosurg Spine · April 1, 2024 OBJECTIVE: The aim of this study was to identify predictors of the best 24-month improvements in patients undergoing surgery for cervical spondylotic myelopathy (CSM). For this purpose, the authors leveraged a large prospective cohort of surgically treated ... Full text Open Access Link to item Cite

Predictors of pelvic tilt normalization: a multicenter study on the impact of regional and lower-extremity compensation on pelvic alignment after complex adult spinal deformity surgery.

Journal Article J Neurosurg Spine · April 1, 2024 OBJECTIVE: The objective was to determine the degree of regional decompensation to pelvic tilt (PT) normalization after complex adult spinal deformity (ASD) surgery. METHODS: Operative ASD patients with 1 year of PT measurements were included. Patients wit ... Full text Open Access Link to item Cite

Does the number of social factors affect long-term patient-reported outcomes and satisfaction in those with cervical myelopathy? A QOD study.

Journal Article J Neurosurg Spine · April 1, 2024 OBJECTIVE: It is not clear whether there is an additive effect of social factors in keeping patients with cervical spondylotic myelopathy (CSM) from achieving both a minimum clinically important difference (MCID) in outcomes and satisfaction after surgery. ... Full text Open Access Link to item Cite

Normative Measurements of L1-S1 Segmental Angulation, Disk Space Height, and Neuroforaminal Dimensions Using Computed Tomography.

Journal Article Neurosurgery · April 1, 2024 BACKGROUND AND OBJECTIVES: To establish normative anatomic measurements of lumbar segmental angulation (SA) and disk space height (DSH) in relation to neuroforaminal dimensions (NFDs), and to uncover the influence of patient demographic and anthropometric ... Full text Open Access Link to item Cite

Functional Alignment Within the Fusion in Adult Spinal Deformity (ASD) Improves Outcomes and Minimizes Mechanical Failures.

Journal Article Spine (Phila Pa 1976) · March 15, 2024 STUDY DESIGN: Retrospective review of an adult deformity database. OBJECTIVE: To identify pelvic incidence (PI) and age-appropriate physical function alignment targets using a component angle of T1-pelvic angle within the fusion to define correction and th ... Full text Open Access Link to item Cite

Using Augmented Reality Technology to Optimize Transfacet Lumbar Interbody Fusion: A Case Report.

Journal Article J Clin Med · March 6, 2024 The transfacet minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) is a novel approach available for the management of lumbar spondylolisthesis. It avoids the need to manipulate either of the exiting or traversing nerve roots, both protect ... Full text Open Access Link to item Cite

Reliability of a Novel Classification System for Thoracic Disc Herniations.

Journal Article Spine (Phila Pa 1976) · March 1, 2024 STUDY DESIGN: This is a cross-sectional survey. OBJECTIVE: The aim was to assess the reliability of a proposed novel classification system for thoracic disc herniations (TDHs). SUMMARY OF BACKGROUND DATA: TDHs are complex entities varying substantially in ... Full text Open Access Link to item Cite

The Case for Operative Efficiency in Adult Spinal Deformity Surgery: Impact of Operative Time on Complications, Length of Stay, Alignment, Fusion Rates, and Patient-Reported Outcomes.

Journal Article Spine (Phila Pa 1976) · March 1, 2024 STUDY DESIGN: Retrospective review of prospectively collected data. OBJECTIVE: To analyze the impact of operative room (OR) time in adult spinal deformity (ASD) surgery on patient outcomes. BACKGROUND: It is currently unknown if OR time in ASD patients mat ... Full text Open Access Link to item Cite

Does diabetes affect outcome or reoperation rate after lumbar decompression or arthrodesis? A matched analysis of the Quality Outcomes Database data set.

Journal Article J Neurosurg Spine · March 1, 2024 OBJECTIVE: Diabetes mellitus (DM) is a known risk factor for postsurgical and systemic complications after lumbar spinal surgery. Smaller studies have also demonstrated diminished improvements in patient-reported outcomes (PROs), with increased reoperation ... Full text Open Access Link to item Cite

Advancing Prone-Transpsoas Spine Surgery: A Narrative Review and Evolution of Indications with Representative Cases.

Journal Article J Clin Med · February 16, 2024 The Prone Transpsoas (PTP) approach to lumbar spine surgery, emerging as an evolution of lateral lumbar interbody fusion (LLIF), offers significant advantages over traditional methods. PTP has demonstrated increased lumbar lordosis gains compared to LLIF, ... Full text Open Access Link to item Cite

Patient-specific Cervical Deformity Corrections With Consideration of Associated Risk: Establishment of Risk Benefit Thresholds for Invasiveness Based on Deformity and Frailty Severity.

Journal Article Clin Spine Surg · February 1, 2024 STUDY DESIGN/SETTING: This was a retrospective cohort study. BACKGROUND: Little is known of the intersection between surgical invasiveness, cervical deformity (CD) severity, and frailty. OBJECTIVE: The aim of this study was to investigate the outcomes of C ... Full text Open Access Link to item Cite

Revision-Free Loss of Sagittal Correction Greater Than Three Years After Adult Spinal Deformity Surgery: Who and Why?

Journal Article Spine (Phila Pa 1976) · February 1, 2024 STUDY DESIGN: Multicenter retrospective cohort study. OBJECTIVE: To investigate risk factors for loss of correction within the instrumented lumbar spine after adult spinal deformity surgery. SUMMARY OF BACKGROUND DATA: The sustainability of adult spinal de ... Full text Open Access Link to item Cite

What factors influence surgical decision-making in anterior versus posterior surgery for cervical myelopathy? A QOD analysis.

Journal Article J Neurosurg Spine · February 1, 2024 OBJECTIVE: The aim of this study was to explore the preoperative patient characteristics that affect surgical decision-making when selecting an anterior or posterior operative approach in patients diagnosed with cervical spondylotic myelopathy (CSM). METHO ... Full text Open Access Link to item Cite

Persistent Lower Extremity Compensation for Sagittal Imbalance After Surgical Correction of Complex Adult Spinal Deformity: A Radiographic Analysis of Early Impact.

Journal Article Oper Neurosurg (Hagerstown) · February 1, 2024 BACKGROUND AND OBJECTIVES: Achieving spinopelvic realignment during adult spinal deformity (ASD) surgery does not always produce ideal outcomes. Little is known whether compensation in lower extremities (LEs) plays a role in this disassociation. The object ... Full text Open Access Link to item Cite

How Much Lumbar Lordosis does a Patient Need to Reach their Age-Adjusted Alignment Target? A Formulated Approach Predicting Successful Surgical Outcomes.

Journal Article Global Spine J · January 2024 STUDY DESIGN: Retrospective cohort study. OBJECTIVES: Identify optimal lumbar lordosis in adult deformity correction to achieve age-adjusted targets and sustained alignment. METHODS: Surgical adult spinal deformity patients reaching an age-adjusted ideal a ... Full text Open Access Link to item Cite

Efficacy of Varying Surgical Approaches on Achieving Optimal Alignment in Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · January 1, 2024 BACKGROUND: The Roussouly, SRS-Schwab, and Global Alignment and Proportion (GAP) classifications define alignment by spinal shape and deformity severity. The efficacy of different surgical approaches and techniques to successfully achieve these goals is no ... Full text Open Access Link to item Cite

Adult cervical spine deformity: a state-of-the-art review.

Journal Article Spine Deform · January 2024 Adult cervical deformity is a structural malalignment of the cervical spine that may present with variety of significant symptomatology for patients. There are clear and substantial negative impacts of cervical spine deformity, including the increased burd ... Full text Open Access Link to item Cite

Determining the best vertebra for measuring pelvic incidence and spinopelvic parameters in adult spinal deformity patients with transitional anatomy.

Journal Article J Neurosurg Spine · January 1, 2024 OBJECTIVE: The aim of this study was to determine if spinal deformity patients with L5 sacralization should have pelvic incidence (PI) and other spinopelvic parameters measured from the L5 or S1 endplate. METHODS: This study was a multicenter retrospective ... Full text Open Access Link to item Cite

Compensation from mild and severe cases of early proximal junctional kyphosis may manifest as progressive cervical deformity at two year follow-up.

Journal Article Spine Deform · January 2024 BACKGROUND: Postoperative reciprocal changes (RC) in the cervical spine associated with varying factors of proximal junctional kyphosis (PJK) following fusions of the thoracopelvic spine are poorly understood. PURPOSE: Explore reciprocal changes in the cer ... Full text Open Access Link to item Cite

What predicts the best 24-month outcomes following surgery for cervical spondylotic myelopathy? A QOD prospective registry study

Journal Article JOURNAL OF NEUROSURGERY-SPINE · 2024 Full text Open Access Cite

Post-operative bracing following adult spine deformity surgery: Results from the AO Spine surveillance of post-operative management of patients with adult spine deformity.

Journal Article PLoS One · 2024 STUDY DESIGN: Cross-sectional international survey with a literature review. OBJECTIVES: While some surgeons favor spine bracing after surgery for adult spine deformity (ASD) to help prevent mechanical failures, there is a lack of evidence. The objective o ... Full text Open Access Link to item Cite

What is the effect of preoperative depression on outcomes after minimally invasive surgery for adult spinal deformity? A prospective cohort analysis

Journal Article JOURNAL OF NEUROSURGERY-SPINE · 2024 Full text Open Access Cite

Analysis of tranexamic acid usage in adult spinal deformity patients with relative contraindications: does it increase the risk of complications?

Journal Article JOURNAL OF NEUROSURGERY-SPINE · 2024 Full text Open Access Cite

A comparative cohort study of surgical approaches for adult spinal deformity at a minimum 2-year follow-up

Journal Article European Spine Journal · January 1, 2024 Study design: This study was a retrospective multi-center comparative cohort study. Materials and methods: A retrospective institutional database of operative adult spinal deformity patients was utilized. All fusions > 5 vertebral levels and including the ... Full text Open Access Cite

Preoperative depression among patients undergoing spine surgery Response

Journal Article JOURNAL OF NEUROSURGERY-SPINE · 2024 Full text Open Access Cite

The Response

Journal Article JOURNAL OF NEUROSURGERY-SPINE · 2024 Full text Cite

Redefining Clinically Significant Blood Loss in Complex Adult Spine Deformity Surgery

Journal Article Spine · January 1, 2024 Study Design. Retrospective analysis of prospectively-collected data Objective. This study aims to define clinically relevant blood loss in adult spinal deformity (ASD) surgery. Background. Current definitions of excessive blood loss following spine surger ... Full text Open Access Cite

Two-Year Clinical and Radiographic Outcomes for Percutaneous Lumbar Interbody Fusion With an Expandable Titanium Cage Through Kambin's Triangle Without Facetectomy.

Journal Article Int J Spine Surg · December 26, 2023 BACKGROUND: There has been heightened interest in performing percutaneous lumbar interbody fusions (percLIFs) through Kambin's triangle, an anatomic corridor allowing entrance into the disc space. However, due to its novelty, there are limited data regardi ... Full text Open Access Link to item Cite

Research using the Quality Outcomes Database: accomplishments and future steps toward higher-quality real-world evidence.

Journal Article J Neurosurg · December 1, 2023 OBJECTIVE: The Quality Outcomes Database (QOD) was established in 2012 by the NeuroPoint Alliance, a nonprofit organization supported by the American Association of Neurological Surgeons. Currently, the QOD has launched six different modules to cover a bro ... Full text Open Access Link to item Cite

The impact of baseline cervical malalignment on the development of proximal junctional kyphosis following surgical correction of thoracolumbar adult spinal deformity.

Journal Article J Neurosurg Spine · December 1, 2023 OBJECTIVE: The objective of this study was to identify the effect of baseline cervical deformity (CD) on proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) in patients with adult spinal deformity (ASD). METHODS: This study was a retro ... Full text Open Access Link to item Cite

Clinical outcomes and proximal junctional failure in adult spinal deformity patients corrected to normative alignment versus functional alignment.

Journal Article J Neurosurg Spine · December 1, 2023 OBJECTIVE: The objective of this study was to explore the rate of proximal junctional failure (PJF) and functional outcomes of normative alignment goals compared with alignment targets based on age-appropriate physical function. METHODS: Baseline relations ... Full text Open Access Link to item Cite

Predictive role of global spinopelvic alignment and upper instrumented vertebra level in symptomatic proximal junctional kyphosis in adult spinal deformity.

Journal Article J Neurosurg Spine · December 1, 2023 OBJECTIVE: The authors of this study sought to evaluate the predictive role of global sagittal alignment and upper instrumented vertebra (UIV) level in symptomatic proximal junctional kyphosis (PJK) among patients with adult spinal deformity (ASD). METHODS ... Full text Open Access Link to item Cite

“Selection, planning and execution of minimally invasive surgery in adult spinal deformity correction”

Journal Article Seminars in Spine Surgery · December 1, 2023 Minimally invasive surgery (MIS) for correction of adult spinal deformity was developed to address the high rate of medical and surgical complications rate in open surgical treatment of increasingly aging and frail patient population. In the past decade, M ... Full text Open Access Cite

Use of supplemental rod constructs in adult spinal deformity surgery

Journal Article Seminars in Spine Surgery · December 1, 2023 Operative treatment for adult spinal deformity (ASD) commonly involves long posterior instrumented fusions with primary rods spanning from the base of the construct to the upper instrumented vertebra. Over the past decade, additional supplemental rods have ... Full text Open Access Cite

Evolving concepts in pelvic fixation in adult spinal deformity surgery

Journal Article Seminars in Spine Surgery · December 1, 2023 Long-segment adult spinal deformity (ASD) constructs carry a high risk of mechanical complications. Pelvic fixation was introduced to improve distal construct mechanics and has since become the standard for long constructs spanning the lumbosacral junction ... Full text Open Access Cite

Economic burden of nonoperative treatment of adult spinal deformity.

Journal Article J Neurosurg Spine · December 1, 2023 OBJECTIVE: The purpose of this study was to investigate the cost utility of nonoperative treatment for adult spinal deformity (ASD). METHODS: Nonoperatively and operatively treated patients who met database criteria for ASD and in whom complete radiographi ... Full text Open Access Link to item Cite

The Benefit of Addressing Malalignment in Revision Surgery for Proximal Junctional Kyphosis Following ASD Surgery.

Journal Article Spine (Phila Pa 1976) · November 15, 2023 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: Understand the benefit of addressing malalignment in revision surgery for proximal junctional kyphosis (PJK). SUMMARY OF BACKGROUND DATA: PJK is a common cause of revision surgery for adult spinal deform ... Full text Open Access Link to item Cite

Activity and sports resumption after long segment fusions to the pelvis for adult spinal deformity: survey results of AO Spine members.

Journal Article Spine Deform · November 2023 PURPOSE: To assess recommendations for when adult spinal deformity (ASD) patients may return to athletic activities after surgery. METHODS: A web-based survey was administered to members of AO Spine. The survey consisted of surgeon demographic information ... Full text Open Access Link to item Cite

When not to Operate in Spinal Deformity: Identifying Subsets of Patients With Simultaneous Clinical Deterioration, Major Complications, and Reoperation.

Journal Article Spine (Phila Pa 1976) · November 1, 2023 STUDY DESIGN: Retrospective review of a prospectively enrolled adult spinal deformity (ASD) database. OBJECTIVE: To investigate what patient factors elevate the risk of sub-optimal outcomes after deformity correction. BACKGROUND: Currently, it is unknown w ... Full text Open Access Link to item Cite

Are we improving in the optimization of surgery for high-risk adult cervical spine deformity patients over time?

Journal Article J Neurosurg Spine · November 1, 2023 OBJECTIVE: The aim of this study was to investigate whether surgery for high-risk patients is being optimized over time and if poor outcomes are being minimized. METHODS: Patients who underwent surgery for cervical deformity (CD) and were ≥ 18 years with b ... Full text Open Access Link to item Cite

Cervical laminoplasty versus laminectomy and posterior cervical fusion for cervical myelopathy: propensity-matched analysis of 24-month outcomes from the Quality Outcomes Database.

Journal Article J Neurosurg Spine · November 1, 2023 OBJECTIVE: Compared with laminectomy with posterior cervical fusion (PCF), cervical laminoplasty (CL) may result in different outcomes for those operated on for cervical spondylotic myelopathy (CSM). The aim of this study was to compare 24-month patient-re ... Full text Open Access Link to item Cite

Greater improvement in Neck Disability Index scores in women after surgery for cervical myelopathy: an analysis of the Quality Outcomes Database.

Journal Article Neurosurg Focus · November 2023 OBJECTIVE: There is a high prevalence of cervical myelopathy that requires surgery; as such, it is important to identify how different groups benefit from surgery. The American Association of Neurological Surgeons launched the Quality Outcomes Database (QO ... Full text Open Access Link to item Cite

International Society for the Advancement of Spine Surgery Statement: Restorative Neurostimulation for Chronic Mechanical Low Back Pain Resulting From Neuromuscular Instability

Journal Article International Journal of Spine Surgery · October 30, 2023 This International Society for the Advancement of Spine Surgery statement has been generated to respond to growing requests for background, supporting literature and evidence, and proper coding for restorative neurostimulation for chronic low back pain. Ch ... Full text Open Access Cite

Predicting Mechanical Failure Following Cervical Deformity Surgery: A Composite Score Integrating Age-Adjusted Cervical Alignment Targets.

Journal Article Global Spine J · October 2023 STUDY DESIGN: Retrospective cohort study. OBJECTIVES: Investigate a composite score to evaluate the relationship between alignment proportionality and risk of distal junctional kyphosis (DJK). METHODS: 84 patients with minimum 1 year follow-up were include ... Full text Open Access Link to item Cite

Failure of nonoperative care in adult symptomatic lumbar scoliosis: incidence, timing, and risk factors for conversion from nonoperative to operative treatment.

Journal Article J Neurosurg Spine · October 1, 2023 OBJECTIVE: The Adult Symptomatic Lumbar Scoliosis (ASLS) study is a prospective multicenter trial with randomized and observational cohorts comparing operative and nonoperative treatment for ASLS. The objective of the present study was to perform a post ho ... Full text Open Access Link to item Cite

Measuring Outcomes in Spinal Deformity Surgery.

Journal Article Neurosurg Clin N Am · October 2023 Outcome assessment in adult spinal deformity has evolved from radiographic analysis of curve correction to patient-centered perception of health-related quality-of-life. Oswestry Disability Index and the Scoliosis Research Society-22 Patient Questionnaire ... Full text Open Access Link to item Cite

Posterior-based Osteotomies for Deformity Correction.

Journal Article Neurosurg Clin N Am · October 2023 Posterior-based osteotomies are crucial to the restoration of lordosis in adult spinal deformity. Posterior-column osteotomies are suited for patients with an unfused anterior column and non-focal sagittal deformity requiring modest correction in lordosis. ... Full text Open Access Link to item Cite

Surgical technique of combined minimally invasive anterior column realignment at L1-L2 with open extension of prior fusion.

Journal Article J Spine Surg · September 22, 2023 Surgical correction of fixed kyphotic deformity or severe sagittal imbalance traditionally involves three column osteotomies, which are associated with high morbidity rates. Anterior column realignment (ACR) has emerged as a minimally invasive alternative ... Full text Open Access Link to item Cite

Height Gain Following Correction of Adult Spinal Deformity.

Journal Article J Bone Joint Surg Am · September 20, 2023 BACKGROUND: Height gain following a surgical procedure for patients with adult spinal deformity (ASD) is incompletely understood, and it is unknown if height gain correlates with patient-reported outcome measures (PROMs). METHODS: This was a retrospective ... Full text Open Access Link to item Cite

Prevention of Surgical Site Infections in Spine Surgery: An International Survey of Clinical Practices Among Expert Spine Surgeons.

Journal Article Global Spine J · September 2023 STUDY DESIGN: Questionnaire-based survey. OBJECTIVES: Surgical site infection (SSI) is a common complication in spine surgery but universal guidelines for SSI prevention are lacking. The objectives of this study are to depict a global status quo on impleme ... Full text Open Access Link to item Cite

Patterns of Lumbar Spine Malalignment Leading to Revision Surgery for Proximal Junctional Kyphosis: A Cluster Analysis of Over- Versus Under-Correction.

Journal Article Global Spine J · September 2023 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: Investigate the patterns of fused lumbar alignment in patients requiring revision surgery for proximal junctional kyphosis (PJK). METHODS: Fifty patients (67.8 yo, 76% female) with existing thoraco-lumba ... Full text Open Access Link to item Cite

History and Accomplishments of the North American Clinical Trials Network for Spinal Cord Injury, 2004-2022.

Journal Article J Neurotrauma · September 2023 This is a historical account of the origin and accomplishments of the North American Clinical Trials Network (NACTN) for traumatic spinal cord injury (SCI), which was established in 2004 by Christopher Reeve and Robert Grossman. Christopher Reeve was an ac ... Full text Open Access Link to item Cite

Trends in the Use of Corticosteroids in the Management of Acute Spinal Cord Injury in North American Clinical Trials Network Sites.

Journal Article J Neurotrauma · September 2023 Immunomodulatory therapeutics represent a potential neuroprotective strategy for the management of acute spinal cord injury (SCI). One of the most intensely debated neuroprotective drugs has been methylprednisolone sodium succinate (MPSS), which was invest ... Full text Open Access Link to item Cite

Demographics, Mechanism of Injury, and Outcomes for Acute Upper and Lower Cervical Spinal Cord Injuries: An Analysis of 470 Patients in the Prospective, Multi-Center, North American Clinical Trials Network Registry.

Journal Article J Neurotrauma · September 2023 There is a paucity of data comparing the demographics, mechanism of injury, and outcomes of upper versus lower cervical spinal cord injuries (cSCI). The study objective was to define different clinical manifestations of cSCI. Data were collected prospectiv ... Full text Open Access Link to item Cite

Bulbocavernosus Reflex Has No Prognostic Features During the Acute Evaluation of Spinal Cord Injuries.

Journal Article J Neurotrauma · September 2023 The bulbocavernosus reflex (BCR) has been used during the initial evaluation of a spinal cord injury patient as a metric to determine prognosis and whether the patient is in "spinal shock." This reflex has been less utilized over the last decade, and there ... Full text Open Access Link to item Cite

Interhospital Transfer Delays Care for Spinal Cord Injury Patients: A Report from the North American Clinical Trials Network for Spinal Cord Injury.

Journal Article J Neurotrauma · September 2023 Abstract The North America Clinical Trials Network (NACTN) for Spinal Cord Injury (SCI) is a consortium of tertiary medical centers that has maintained a prospective SCI registry since 2004, and it has espoused that early surgical intervention is associate ... Full text Open Access Link to item Cite

Variability in Early Surgery for Acute Cervical Spinal Cord Injury Patients: An Opportunity for Enhanced Care Delivery.

Journal Article J Neurotrauma · September 2023 Data supporting the benefits of early surgical intervention in acute spinal cord injury (SCI) is growing. For early surgery to be accomplished, understanding the causes of variabilities that effect the timing of surgery is needed to achieve this goal. The ... Full text Open Access Link to item Cite

Calibration of a comprehensive predictive model for the development of proximal junctional kyphosis and failure in adult spinal deformity patients with consideration of contemporary goals and techniques.

Journal Article J Neurosurg Spine · September 1, 2023 OBJECTIVE: The objective of this study was to calibrate an updated predictive model incorporating novel clinical, radiographic, and prophylactic measures to assess the risk of proximal junctional kyphosis (PJK) and failure (PJF). METHODS: Operative patient ... Full text Open Access Link to item Cite

Use of multiple rods and proximal junctional kyphosis in adult spinal deformity surgery.

Journal Article J Neurosurg Spine · September 1, 2023 OBJECTIVE: Multiple rods are utilized in adult spinal deformity (ASD) surgery to increase construct stiffness. However, the impact of multiple rods on proximal junctional kyphosis (PJK) is not well established. This study aimed to investigate the impact of ... Full text Open Access Link to item Cite

Treatment of adult deformity surgery by orthopedic and neurological surgeons: trends in treatment, techniques, and costs by specialty.

Journal Article Spine J · September 2023 BACKGROUND CONTEXT: Surgery to correct adult spinal deformity (ASD) is performed by both neurological surgeons and orthopedic surgeons. Despite well-documented high costs and complication rates following ASD surgery, there is a dearth of research investiga ... Full text Open Access Link to item Cite

Three-level ACDF versus 3-level laminectomy and fusion: are there differences in outcomes? An analysis of the Quality Outcomes Database cervical spondylotic myelopathy cohort.

Journal Article Neurosurg Focus · September 2023 OBJECTIVE: The authors sought to compare 3-level anterior with posterior fusion surgical procedures for the treatment of multilevel cervical spondylotic myelopathy (CSM). METHODS: The authors analyzed prospective data from the 14 highest enrolling sites of ... Full text Open Access Link to item Cite

Surgeon input can increase the value of registry data: early experience from the American Spine Registry.

Journal Article J Neurosurg Spine · September 1, 2023 OBJECTIVE: Clear diagnostic delineation is necessary for the development of a strong evidence base in lumbar spinal surgery. Experience with existing national databases suggests that International Classification of Diseases, Tenth Edition (ICD-10) coding i ... Full text Open Access Link to item Cite

Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery.

Journal Article J Clin Med · August 26, 2023 BACKGROUND: While reimbursement is centered on 90-day outcomes, many patients may still achieve optimal, long-term outcomes following adult spinal deformity (ASD) surgery despite transient short-term complications. OBJECTIVE: Compare long-term clinical suc ... Full text Open Access Link to item Cite

Identifying Subsets of Patients With Adult Spinal Deformity Who Maintained a Positive Response to Nonoperative Management.

Journal Article Neurosurgery · August 1, 2023 BACKGROUND: Adult spinal deformity (ASD) represents a major cause of disability in the elderly population in the United States. Surgical intervention has been shown to reduce disability and pain in properly indicated patients. However, there is a small sub ... Full text Open Access Link to item Cite

Quantifying the Contribution of Lower Limb Compensation to Upright Posture: What Happens If Adult Spinal Deformity Patients Do Not Compensate?

Journal Article Spine (Phila Pa 1976) · August 1, 2023 STUDY DESIGN: This is a multicenter, prospective cohort study. OBJECTIVE: This study tests the hypothesis that the elimination of lower limb compensation in patients with adult spinal deformity (ASD) will significantly increase the magnitude of sagittal ma ... Full text Open Access Link to item Cite

Incremental benefits of circumferential minimally invasive surgery for increasingly frail patients with adult spinal deformity.

Journal Article J Neurosurg Spine · August 1, 2023 OBJECTIVE: Circumferential minimally invasive surgery (cMIS) may provide incremental benefits compared with open surgery for patients with increasing frailty status by decreasing peri- and postoperative complications. METHODS: Operative patients with adult ... Full text Open Access Link to item Cite

Awake Spinal Fusion Is Associated with Reduced Length of Stay, Opioid Use, and Time to Ambulation Compared to General Anesthesia: A Matched Cohort Study.

Journal Article World Neurosurg · August 2023 OBJECTIVE: There is increasing interest in performing awake spinal fusion under spinal anesthesia (SA). Evidence supporting SA has been positive, albeit limited. The authors set out to investigate the effects of SA versus general anesthesia (GA) for spinal ... Full text Open Access Link to item Cite

Would you do it again? Discrepancies between patient and surgeon perceptions following adult spine deformity surgery.

Journal Article Spine J · August 2023 BACKGROUND: Adult spinal deformity (ASD) surgery can improve patient pain and physical function but is associated with high complication rates and long postoperative recovery. Accordingly, if given a choice, patients may indicate they would not undergo ASD ... Full text Open Access Link to item Cite

Patient and procedural risk factors for decline in lower-extremity motor scores following adult spinal deformity surgery.

Journal Article J Neurosurg Spine · August 1, 2023 OBJECTIVE: The purpose of this study was to discern factors that differentiate patients who experience postoperative lower-extremity motor function decline in the early postoperative period. METHODS: Adult spinal deformity (ASD) patients who were enrolled ... Full text Open Access Link to item Cite

Longitudinal Assessment of Modern Spine Surgery Training: 10-Year Follow-up of a Nationwide Survey of Residency and Spine Fellowship Program Directors

Journal Article JBJS Open Access · August 1, 2023 Background:Spine surgeons complete training through residency in orthopaedic surgery (ORTH) or neurosurgery (NSGY). A survey was conducted in 2013 to evaluate spine surgery training. Over the past decade, advances in surgical techniques and the changing dy ... Full text Open Access Cite

One-year Postoperative Radiographic and Patient-reported Outcomes Following Cervical Deformity Correction Are Not Affected by a Short-term Unplanned Return to the OR.

Journal Article Spine (Phila Pa 1976) · July 15, 2023 STUDY DESIGN: Retrospective analysis of a prospectively collected multicenter database. OBJECTIVE: The objective of this study was to assess the radiographic and health-related quality of life (HRQoL) impact of a short-term (<1 y) return to the operating r ... Full text Open Access Link to item Cite

Spinopelvic sagittal compensation in adult cervical deformity.

Journal Article J Neurosurg Spine · July 1, 2023 OBJECTIVE: The objective of this study was to evaluate spinopelvic sagittal alignment and spinal compensatory changes in adult cervical kyphotic deformity. METHODS: A database composed of 13 US spine centers was retrospectively reviewed for adult patients ... Full text Open Access Link to item Cite

Do comorbid self-reported depression and anxiety influence outcomes following surgery for cervical spondylotic myelopathy?

Journal Article J Neurosurg Spine · July 1, 2023 OBJECTIVE: Depression and anxiety are associated with inferior outcomes following spine surgery. In this study, the authors examined whether patients with cervical spondylotic myelopathy (CSM) who have both self-reported depression (SRD) and self-reported ... Full text Open Access Link to item Cite

Novel Approach to Percutaneous Lumbar Surgeries via Kambin's Triangle-Radiographic and Surgical Planning Analysis with Nerve Segmentation Technology.

Journal Article World Neurosurg · June 22, 2023 OBJECTIVE: While Kambin's Triangle has become an ever more important anatomic window given its proximity to the exiting nerve root, there have been limited studies examining the effect of disease on the corridor. Our goal was to better understand how patho ... Full text Open Access Link to item Cite

Which supervised machine learning algorithm can best predict achievement of minimum clinically important difference in neck pain after surgery in patients with cervical myelopathy? A QOD study.

Journal Article Neurosurg Focus · June 2023 OBJECTIVE: The purpose of this study was to evaluate the performance of different supervised machine learning algorithms to predict achievement of minimum clinically important difference (MCID) in neck pain after surgery in patients with cervical spondylot ... Full text Open Access Link to item Cite

Developing nonlinear k-nearest neighbors classification algorithms to identify patients at high risk of increased length of hospital stay following spine surgery.

Journal Article Neurosurg Focus · June 2023 OBJECTIVE: Spondylolisthesis is a common operative disease in the United States, but robust predictive models for patient outcomes remain limited. The development of models that accurately predict postoperative outcomes would be useful to help identify pat ... Full text Open Access Link to item Cite

Cervicothoracic Versus Proximal Thoracic Lower Instrumented Vertebra Have Comparable Radiographic and Clinical Outcomes in Adult Cervical Deformity.

Journal Article Global Spine J · May 2023 STUDY DESIGN: Comparative cohort study. OBJECTIVE: Factors that influence the lower instrumented vertebra (LIV) selection in adult cervical deformity (ACD) are less reported, and outcomes in the cervicothoracic junction (CTJ) and proximal thoracic (PT) spi ... Full text Open Access Link to item Cite

Lowest Instrumented Vertebra Selection to S1 or Ilium Versus L4 or L5 in Adult Spinal Deformity: Factors for Consideration in 349 Patients With a Mean 46-Month Follow-Up

Journal Article Global Spine Journal · May 1, 2023 Study Design: Retrospective cohort study. Objective: To compare the outcomes of patients with adult spinal deformity (ASD) following spinal fusion with the lowest instrumented vertebra (LIV) at L4/L5 versus S1/ilium. Methods: A multicenter ASD database was ... Full text Open Access Cite

Pelvic Nonresponse Following Treatment of Adult Spinal Deformity: Influence of Realignment Strategies on Occurrence.

Journal Article Spine (Phila Pa 1976) · May 1, 2023 PURPOSE: Despite adequate correction, the pelvis may fail to readjust, deemed pelvic nonresponse (PNR). To assess alignment outcomes [PNR, proximal junctional kyphosis (PJK), postoperative cervical deformity (CD)] following adult spinal deformity (ASD) sur ... Full text Open Access Link to item Cite

Changes in health-related quality of life measures associated with degree of proximal junctional kyphosis.

Journal Article Spine Deform · May 2023 PURPOSE: To explore the changes in health-related quality of life parameters observed in patients experiencing varying degrees of proximal junctional kyphosis following corrective adult spinal deformity fusions. METHODS: Inclusion: adult spinal deformity p ... Full text Open Access Link to item Cite

How closely are outcome questionnaires correlated to patient satisfaction after cervical spine surgery for myelopathy?

Journal Article J Neurosurg Spine · May 1, 2023 OBJECTIVE: Patient-reported outcomes (PROs) have become the standard means to measure surgical outcomes. Insurers and policy makers are also increasingly utilizing PROs to assess the value of care and measure different aspects of a patient's condition. For ... Full text Open Access Link to item Cite

Characteristics of patients who return to work after undergoing surgery for cervical spondylotic myelopathy: a Quality Outcomes Database study.

Journal Article J Neurosurg Spine · May 1, 2023 OBJECTIVE: Return to work (RTW) is an important surgical outcome for patients who are employed, yet a significant number of patients with cervical spondylotic myelopathy (CSM) who are employed undergo cervical spine surgery and fail to RTW. In this study, ... Full text Open Access Link to item Cite

Can unsupervised cluster analysis identify patterns of complex adult spinal deformity with distinct perioperative outcomes?

Journal Article J Neurosurg Spine · May 1, 2023 OBJECTIVE: The objective of this study was to use an unsupervised cluster approach to identify patterns of operative adult spinal deformity (ASD) and compare the perioperative outcomes of these groups. METHODS: A multicenter data set included patients with ... Full text Open Access Link to item Cite

Spine Surgical Subspecialty and Its Effect on Patient Outcomes: A Systematic Review and Meta-Analysis.

Journal Article Spine (Phila Pa 1976) · May 1, 2023 STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To perform a systematic review and meta-analysis to identify if intraoperative or postoperative differences in outcomes exist between orthopedic and neurological spine surgeons. SUMMARY OF BACKG ... Full text Open Access Link to item Cite

Distal junctional kyphosis in adult cervical deformity patients: where does it occur?

Journal Article Eur Spine J · May 2023 PURPOSE: To evaluate the impact of the lowest instrumented vertebra (LIV) on Distal Junctional kyphosis (DJK) incidence in adult cervical deformity (ACD) surgery. METHODS: Prospectively collected data from ACD patients undergoing posterior or anterior-post ... Full text Open Access Link to item Cite

Awake spinal anesthesia facilitates spine surgery in poor surgical candidates: A case series.

Journal Article Neurochirurgie · May 2023 BACKGROUND: Annually, hundreds of thousands of patients undergo surgery for degenerative spine disease (DSD). This represents only a fraction of patients that present for surgical consideration. Procedures are often avoided due to comorbidities that make p ... Full text Open Access Link to item Cite

Effect of Restorative Neurostimulation on Major Drivers of Chronic Low Back Pain Economic Impact.

Journal Article Neurosurgery · April 1, 2023 BACKGROUND: High-impact chronic low back pain (CLBP) correlates with high healthcare resource utilization. Therapies that can alter impact status may provide beneficial long-term economic benefits. An implantable restorative neurostimulation system (ReActi ... Full text Open Access Link to item Cite

Sleep Disturbances in Cervical Spondylotic Myelopathy: Prevalence and Postoperative Outcomes-an Analysis From the Quality Outcomes Database.

Journal Article Clin Spine Surg · April 1, 2023 STUDY DESIGN: Prospective observational study, level of evidence 1 for prognostic investigations. OBJECTIVES: To evaluate the prevalence of sleep impairment and predictors of improved sleep quality 24 months postoperatively in cervical spondylotic myelopat ... Full text Open Access Link to item Cite

Optimizing the Definition of Proximal Junctional Kyphosis: A Sensitivity Analysis.

Journal Article Spine (Phila Pa 1976) · March 15, 2023 STUDY DESIGN: Diagnostic binary threshold analysis. OBJECTIVE: (1) Perform a sensitivity analysis demonstrating the test performance metrics for any combination of proximal junctional angle (PJA) magnitude and change; (2) Propose a new proximal junctional ... Full text Open Access Link to item Cite

High-Impact Chronic Pain Transition in Lumbar Surgery Recipients.

Journal Article Pain Med · March 1, 2023 OBJECTIVE: High-impact chronic pain (HICP) is a term that characterizes the presence of a severe and troubling pain-related condition. To date, the prevalence of HICP in lumbar spine surgery recipients and their HICP transitions from before to after surger ... Full text Open Access Link to item Cite

Development of new postoperative neck pain at 12 and 24 months after surgery for cervical spondylotic myelopathy: a Quality Outcomes Database study.

Journal Article J Neurosurg Spine · March 1, 2023 OBJECTIVE: Patients who undergo surgery for cervical spondylotic myelopathy (CSM) will occasionally develop postoperative neck pain that was not present preoperatively, yet the incidence of this phenomenon is unclear. The authors aimed to elucidate patient ... Full text Open Access Link to item Cite

Proximal junctional failure in primary thoracolumbar fusion/fixation to the sacrum/pelvis for adult symptomatic lumbar scoliosis: long-term follow-up of a prospective multicenter cohort of 160 patients.

Journal Article J Neurosurg Spine · March 1, 2023 OBJECTIVE: Proximal junctional failure (PJF) is a severe form of proximal junctional kyphosis. Previous reports on PJF have been limited by heterogeneous cohorts and relatively short follow-ups. The authors' objectives herein were to identify risk factors ... Full text Open Access Link to item Cite

Diagnosis-Related Group-Based Payments for Adult Spine Deformity Surgery Significantly Vary across Centers: Results from a Multicenter Prospective Cohort Study.

Journal Article World Neurosurg · March 2023 BACKGROUND: To investigate the variation in total episode-of-care (EOC) payment and quality-adjusted life-year (QALY) gain for complex adult spine deformity surgeries in the United States, adjusting for case type and surgeon preferences. METHODS: Patients ... Full text Open Access Link to item Cite

Author Correction: Sagittal age-adjusted score (SAAS) for adult spinal deformity (ASD) more effectively predicts surgical outcomes and proximal junctional kyphosis than previous classifications.

Journal Article Spine Deform · March 2023 Full text Open Access Link to item Cite

Novel Merging of CT and MRI to Allow for Safe Navigation into Kambin's Triangle for Percutaneous Lumbar Interbody Fusion-Initial Case Series Investigating Safety and Efficacy.

Journal Article Oper Neurosurg (Hagerstown) · March 1, 2023 BACKGROUND: For percutaneous lumbar fusion (percLIF), magnetic resonance imaging and computed tomography are critical to defining surgical corridors. Currently, these scans are performed separately, and surgeons then use fluoroscopy or neuromonitoring to g ... Full text Open Access Link to item Cite

Predicting the Magnitude of Distal Junctional Kyphosis Following Cervical Deformity Correction.

Journal Article Spine (Phila Pa 1976) · February 15, 2023 STUDY DESIGN: Retrospective review of a cervical deformity database. OBJECTIVE: This study aimed to develop a model that can predict the postoperative distal junctional kyphosis angle (DJKA) using preoperative and postoperative radiographic measurements. S ... Full text Open Access Link to item Cite

Leveraging machine learning to ascertain the implications of preoperative body mass index on surgical outcomes for 282 patients with preoperative obesity and lumbar spondylolisthesis in the Quality Outcomes Database.

Journal Article J Neurosurg Spine · February 1, 2023 OBJECTIVE: Prior studies have revealed that a body mass index (BMI) ≥ 30 is associated with worse outcomes following surgical intervention in grade 1 lumbar spondylolisthesis. Using a machine learning approach, this study aimed to leverage the prospective ... Full text Open Access Link to item Cite

Improvements in Outcomes and Cost After Adult Spinal Deformity Corrective Surgery Between 2008 and 2019.

Journal Article Spine (Phila Pa 1976) · February 1, 2023 STUDY DESIGN: A retrospective cohort study. OBJECTIVE: To assess whether patient outcomes and cost-effectiveness of adult spinal deformity (ASD) surgery have improved over the past decade. BACKGROUND: Surgery for ASD is an effective intervention, but one t ... Full text Open Access Link to item Cite

Rod fractures in thoracolumbar fusions to the sacrum/pelvis for adult symptomatic lumbar scoliosis: long-term follow-up of a prospective, multicenter cohort of 160 patients.

Journal Article J Neurosurg Spine · February 1, 2023 OBJECTIVE: Previous reports of rod fracture (RF) in adult spinal deformity are limited by heterogeneous cohorts, low follow-up rates, and relatively short follow-up durations. Since the majority of RFs present > 2 years after surgery, true occurrence and r ... Full text Open Access Link to item Cite

Comparable satisfaction and clinical outcomes after surgery for adolescent idiopathic scoliosis in the adult (AISA) between the US and Japan.

Journal Article J Orthop Sci · January 2023 BACKGROUND: The impact of ethnicity on the surgery outcomes of adolescent idiopathic scoliosis in the adult (AISA) is poorly understood. This study aimed to compare the surgery outcomes for AISA between the United States (US) and Japan (JP). METHODS: 171 s ... Full text Open Access Link to item Cite

Validation of Adult Spinal Deformity Surgical Outcome Prediction Tools in Adult Symptomatic Lumbar Scoliosis.

Journal Article Spine (Phila Pa 1976) · January 1, 2023 STUDY DESIGN: A post hoc analysis. OBJECTIVE: Advances in machine learning (ML) have led to tools offering individualized outcome predictions for adult spinal deformity (ASD). Our objective is to examine the properties of these ASD models in a cohort of ad ... Full text Open Access Link to item Cite

Establishment of an Individualized Distal Junctional Kyphosis Risk Index following the Surgical Treatment of Adult Cervical Deformities.

Journal Article Spine (Phila Pa 1976) · January 1, 2023 STUDY DESIGN: A retrospective review of a multicenter comprehensive cervical deformity (CD) database. OBJECTIVE: To develop a novel risk index specific to each patient to aid in patient counseling and surgical planning to minimize postop distal junctional ... Full text Open Access Link to item Cite

Cervical spondylotic myelopathy with severe axial neck pain: is anterior or posterior approach better?

Journal Article J Neurosurg Spine · January 1, 2023 OBJECTIVE: The aim of this study was to determine whether multilevel anterior cervical discectomy and fusion (ACDF) or posterior cervical laminectomy and fusion (PCLF) is superior for patients with cervical spondylotic myelopathy (CSM) and high preoperativ ... Full text Open Access Link to item Cite

Patient satisfaction after multiple revision surgeries for adult spinal deformity.

Journal Article J Neurosurg Spine · January 1, 2023 OBJECTIVE: Revision surgery is often necessary for adult spinal deformity (ASD) patients. Satisfaction with management is an important component of health-related quality of life. The authors hypothesized that patients who underwent multiple revision surge ... Full text Open Access Link to item Cite

Return to work after adult spinal deformity surgery.

Journal Article Spine Deform · January 2023 PURPOSE: To determine the proportions of patients returning to work at various points after adult spinal deformity (ASD) surgery and the associations between surgical invasiveness and time to return to work. METHODS: Using a multicenter database of patient ... Full text Open Access Link to item Cite

Instrument Tracking for Prone Lateral Surgery.

Journal Article World Neurosurg · January 2023 The prone lateral transpsoas approach for lumbar interbody fusion and posterior instrumentation enables a large surface area implant without disruption of the posterior spine musculature from a single position.1,2 The addition of virtual live fluoroscopy i ... Full text Open Access Link to item Cite

Minimally invasive versus open transforaminal lumbar interbody fusion for grade I lumbar spondylolisthesis: 5-year follow-up from the prospective multicenter Quality Outcomes Database registry.

Journal Article Neurosurg Focus · January 2023 OBJECTIVE: Minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) has been used to treat degenerative lumbar spondylolisthesis and is associated with expedited recovery, reduced operative blood loss, and shorter hospitalizations compared to th ... Full text Open Access Link to item Cite

Foreword

Book · January 1, 2023 Cite

Awake Spinal Fusion Leads to Decreased Postoperative Opioid Use and Decreased Length of Stay Compared to General Anesthesia: A Matched Cohort Study

Conference NEUROSURGERY · 2023 Cite

Beyond Placement of Pedicle Screws - New Applications for Robotics in Spine Surgery: A Multi-Surgeon, Single-Institution Experience

Conference NEUROSURGERY · 2023 Open Access Cite

Awake Spine Surgery for Traditionally Poor Surgical Candidates: An Illustrative Cohort

Conference NEUROSURGERY · 2023 Cite

Assessing Correlations Between NASS Patient Satisfaction Index and Patient-Reported Outcomes (PROs) at 3-month, 12-month, and 24-month Timepoints in Patients Undergoing Cervical Spine Surgery Using the QOD Registry

Conference NEUROSURGERY · 2023 Cite

Operative treatment outcomes for adult cervical deformity: a prospective multicenter assessment with mean 3-year follow-up.

Journal Article J Neurosurg Spine · December 1, 2022 OBJECTIVE: Adult cervical deformity (ACD) has high complication rates due to surgical complexity and patient frailty. Very few studies have focused on longer-term outcomes of operative ACD treatment. The objective of this study was to assess minimum 2-year ... Full text Open Access Link to item Cite

Correlation of the Modified Japanese Orthopedic Association With Functional and Quality-of-Life Outcomes After Surgery for Degenerative Cervical Myelopathy: A Quality Outcomes Database Study.

Journal Article Neurosurgery · December 1, 2022 BACKGROUND: The modified Japanese Orthopedic Association (mJOA) score is a widely used and validated metric for assessing severity of myelopathy. Its relationship to functional and quality-of-life outcomes after surgery has not been fully described. OBJECT ... Full text Open Access Link to item Cite

Real-World Evidence for Restorative Neurostimulation in Chronic Low Back Pain-a Consecutive Cohort Study.

Journal Article World Neurosurg · December 2022 BACKGROUND: Neuromuscular instability of the lumbar spine resulting from impaired motor control and degeneration of the multifidus muscle is a known root cause of refractory chronic low back pain (LBP). An implantable neurostimulation system that aims to r ... Full text Open Access Link to item Cite

Development of Risk Stratification Predictive Models for Cervical Deformity Surgery.

Journal Article Neurosurgery · December 1, 2022 BACKGROUND: As corrective surgery for cervical deformity (CD) increases, so does the rate of complications and reoperations. To minimize suboptimal postoperative outcomes, it is important to develop a tool that allows for proper preoperative risk stratific ... Full text Open Access Link to item Cite

Evolution of Adult Cervical Deformity Surgery Clinical and Radiographic Outcomes Based on a Multicenter Prospective Study: Are Behaviors and Outcomes Changing With Experience?

Journal Article Spine (Phila Pa 1976) · November 15, 2022 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: Assess changes in outcomes and surgical approaches for adult cervical deformity surgery over time. SUMMARY OF BACKGROUND DATA: As the population ages and the prevalence of cervical deformity increases, c ... Full text Open Access Link to item Cite

Three-Column Osteotomy in Adult Spinal Deformity: An Analysis of Temporal Trends in Usage and Outcomes.

Journal Article J Bone Joint Surg Am · November 2, 2022 BACKGROUND: Three-column osteotomies (3COs), usually in the form of pedicle subtraction or vertebral column resection, have become common in adult spinal deformity surgery. Although a powerful tool for deformity correction, 3COs can increase the risks of p ... Full text Open Access Link to item Cite

Dr. Ruth Jackson: the legacy of the first female spine surgeon.

Journal Article J Neurosurg Spine · November 1, 2022 Dr. Ruth Jackson, born in 1902, was the first female spine surgeon on record. Her story of remarkable resilience and sacrifice is even more relevant given the stark gender disparities in orthopedic surgery and neurosurgery that remain today. Dr. Jackson en ... Full text Open Access Link to item Cite

Highest Achievable Outcomes for Patients Undergoing Cervical Deformity Corrective Surgery by Frailty.

Journal Article Neurosurgery · November 1, 2022 BACKGROUND: Frailty is influential in determining operative outcomes, including complications, in patients with cervical deformity (CD). OBJECTIVE: To assess whether frailty status limits the highest achievable outcomes of patients with CD. METHODS: Adult ... Full text Open Access Link to item Cite

Primary Spinal Cord Astrocytomas: Two-Center Clinical Experience of Low- and High-Grade Lesions.

Journal Article World Neurosurg · November 2022 OBJECTIVE: Primary spinal cord astrocytomas are rare, fatal, and poorly studied. METHODS: This study included a 2-center, retrospective analysis of primary spinal cord astrocytoma patients from 1997 to 2020. Patients with drop metastases or without at leas ... Full text Open Access Link to item Cite

The Additional Economic Burden of Frailty in Adult Cervical Deformity Patients Undergoing Surgical Intervention.

Journal Article Spine (Phila Pa 1976) · October 15, 2022 SUMMARY OF BACKGROUND DATA: The influence of frailty on economic burden following corrective surgery for the adult cervical deformity (CD) is understudied and may provide valuable insights for preoperative planning. OBJECTIVE: To assess the influence of ba ... Full text Open Access Link to item Cite

Patient-Reported Outcomes After Complex Adult Spinal Deformity Surgery: 5-Year Results of the Scoli-Risk-1 Study.

Journal Article Global Spine J · October 2022 STUDY DESIGN: Prospective cohort. OBJECTIVE: To prospectively evaluate PROs up to 5-years after complex ASD surgery. METHODS: The Scoli-RISK-1 study enrolled 272 ASD patients undergoing surgery from 15 centers. Inclusion criteria was Cobb angle of >80°, co ... Full text Open Access Link to item Cite

Surgical Planning for Adult Spinal Deformity: Anticipated Sagittal Alignment Corrections According to the Surgical Level.

Journal Article Global Spine J · October 2022 STUDY DESIGN: Retrospective cohort study. OBJECTIVES: Establish simultaneous focal and regional corrective guidelines accounting for reciprocal global and pelvic compensation. METHODS: 433 ASD patients (mean age 62.9 yrs, 81.3% F) who underwent corrective ... Full text Open Access Link to item Cite

Proximal and distal reciprocal changes following cervical deformity malalignment correction.

Journal Article J Neurosurg Spine · October 1, 2022 OBJECTIVE: Hyperextension of C0-2 is a debilitating compensatory mechanism used to maintain horizontal gaze, analogous to high pelvic tilt in the lumbopelvic complex to maintain an upright posture. This study aims to investigate the impact of cervical defo ... Full text Open Access Link to item Cite

Outcomes of operative treatment for adult spinal deformity: a prospective multicenter assessment with mean 4-year follow-up.

Journal Article J Neurosurg Spine · October 1, 2022 OBJECTIVE: The current literature has primarily focused on the 2-year outcomes of operative adult spinal deformity (ASD) treatment. Longer term durability is important given the invasiveness, complications, and costs of these procedures. The aim of this st ... Full text Open Access Link to item Cite

Differences in postoperative quality of life in young, early elderly, and late elderly patients undergoing surgical treatment for degenerative cervical myelopathy.

Journal Article J Neurosurg Spine · September 1, 2022 OBJECTIVE: Cervical spondylotic myelopathy (CSM) is a common progressive spine disorder affecting predominantly middle-aged and elderly populations. With increasing life expectancy, the incidence of CSM is expected to rise further. The outcomes of elderly ... Full text Open Access Link to item Cite

Individual differences in postoperative recovery trajectories for adult symptomatic lumbar scoliosis.

Journal Article J Neurosurg Spine · September 1, 2022 OBJECTIVE: The Adult Symptomatic Lumbar Scoliosis-1 (ASLS-1) trial demonstrated the benefit of adult symptomatic lumbar scoliosis (ASLS) surgery. However, the extent to which individuals differ in their postoperative recovery trajectories is unknown. This ... Full text Open Access Link to item Cite

Single-position prone transpsoas fusion for the treatment of lumbar adjacent segment disease: early experience of twenty-four cases across three tertiary medical centers.

Journal Article Eur Spine J · September 2022 PURPOSE: Prone transpsoas fusion (PTP) is a minimally invasive technique that maximizes the benefit of lateral access interbody surgery and the prone positioning for surgically significant adjacent segment disease. The authors describe the feasibility, rep ... Full text Open Access Link to item Cite

Are Minimally Invasive Spine Surgeons or Classical Open Spine Surgeons More Consistent with Their Treatment of Adult Spinal Deformity?

Journal Article World Neurosurg · September 2022 OBJECTIVE: Spine surgeons have a heuristic sense of how to surgically restore alignment and address adult spinal deformity (ASD) symptoms, but consensus on the extent of treatment remains unclear. We sought to determine the variability of surgical approach ... Full text Open Access Link to item Cite

Upper versus Lower Lumbar Lordosis Corrections in Relation to Pelvic Tilt - An Essential Element in Surgical Planning for Sagittal Plane Deformity.

Journal Article Spine (Phila Pa 1976) · August 15, 2022 STUDY DESIGN: Retrospective study of a multicenter Adult Spinal Deformity (ASD) Database. OBJECTIVE: To investigate the change in Pelvic tilt (PT) imparted by regional changes in lumbar lordosis at 2-year minimum follow up. SUMMARY OF BACKGROUND DATA: The ... Full text Open Access Link to item Cite

Role of obesity in less radiographic correction and worse health-related quality-of-life outcomes following minimally invasive deformity surgery.

Journal Article J Neurosurg Spine · August 1, 2022 OBJECTIVE: Minimally invasive surgery (MIS) for adult spinal deformity (ASD) can offer deformity correction with less tissue manipulation and damage. However, the impact of obesity on clinical outcomes and radiographic correction following MIS for ASD is p ... Full text Open Access Link to item Cite

Inferior Clinical Outcomes for Patients with Medicaid Insurance After Surgery for Degenerative Lumbar Spondylolisthesis: A Prospective Registry Analysis of 608 Patients.

Journal Article World Neurosurg · August 2022 BACKGROUND: It remains unclear how type of insurance coverage affects long-term, spine-specific patient-reported outcomes (PROs). This study sought to elucidate the impact of insurance on clinical outcomes after lumbar spondylolisthesis surgery. METHODS: T ... Full text Open Access Link to item Cite

Rates of Loosening, Failure, and Revision of Iliac Fixation in Adult Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · July 15, 2022 STUDY DESIGN: Retrospective cohort review of a prospective multicenter database. OBJECTIVE: Identify rates and variations in lumbopelvic fixation failure after adult spinal deformity (ASD) correction. SUMMARY OF BACKGROUND DATA: Traditional iliac (IS) and ... Full text Open Access Link to item Cite

Neurological Complications and Recovery Rates of Patients With Adult Cervical Deformity Surgeries.

Journal Article Global Spine J · July 2022 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: This study aims to report the incidence, risk factors, and recovery rate of neurological complications (NC) in patients with adult cervical deformity (ACD) who underwent corrective surgery. METHODS: ACD ... Full text Open Access Link to item Cite

Alignment Targets, Curve Proportion and Mechanical Loading: Preliminary Analysis of an Ideal Shape Toward Reducing Proximal Junctional Kyphosis.

Journal Article Global Spine J · July 2022 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: Investigate risk factors for PJK including theoretical kyphosis, mechanical loading at the UIV and age adjusted offset alignment. METHODS: 373 ASD patients (62.7 yrs ± 9.9; 81%F) with 2-year follow up an ... Full text Open Access Link to item Cite

High-impact chronic pain transition in surgical recipients with cervical spondylotic myelopathy.

Journal Article J Neurosurg Spine · July 1, 2022 OBJECTIVE: High-impact chronic pain (HICP) is a recently proposed metric that indicates the presence of a severe and troubling pain-related condition. Surgery for cervical spondylotic myelopathy (CSM) is designed to halt disease transition independent of c ... Full text Open Access Link to item Cite

Social risk factors predicting outcomes of cervical myelopathy surgery.

Journal Article J Neurosurg Spine · July 1, 2022 OBJECTIVE: Combinations of certain social risk factors of race, sex, education, socioeconomic status (SES), insurance, education, employment, and one's housing situation have been associated with poorer pain and disability outcomes after lumbar spine surge ... Full text Open Access Link to item Cite

Patient-reported outcome measure clustering after surgery for adult symptomatic lumbar scoliosis.

Journal Article J Neurosurg Spine · July 1, 2022 OBJECTIVE: Adult symptomatic lumbar scoliosis (ASLS) is a widespread and debilitating subset of adult spinal deformity. Although many patients benefit from operative treatment, surgery entails substantial cost and risk for adverse events. Patient-reported ... Full text Open Access Link to item Cite

Is frailty responsive to surgical correction of adult spinal deformity? An investigation of sagittal re-alignment and frailty component drivers of postoperative frailty status.

Journal Article Spine Deform · July 2022 PURPOSE: Frailty has been associated with adverse postoperative outcomes. Recently, a novel frailty index for preoperative risk stratification in patients with adult spinal deformity was developed. Components of the ASD-FI utilize patient comorbidity, clin ... Full text Open Access Link to item Cite

Evolution of Proximal Junctional Kyphosis and Proximal Junctional Failure Rates Over 10 Years of Enrollment in a Prospective Multicenter Adult Spinal Deformity Database.

Journal Article Spine (Phila Pa 1976) · July 1, 2022 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: The aim of this study was to investigate the evolution of proximal junctional kyphosis (PJK) rate over 10-year enrollment period within a prospective database. SUMMARY OF BACKGROUND DATA: PJK is a common ... Full text Open Access Link to item Cite

Sacroiliac Joint Fusion Using Robotic Navigation: Technical Note and Case Series.

Conference Oper Neurosurg (Hagerstown) · July 1, 2022 BACKGROUND: Patients undergoing sacroiliac (SI) fusion can oftentimes experience significant improvements in pain and quality of life. OBJECTIVE: To describe a novel application of robotic navigation to assist with minimally invasive SI joint fusion. METHO ... Full text Link to item Cite

Minimally invasive lateral retroperitoneal transpsoas approach for lumbar corpectomy and fusion with posterior instrumentation.

Journal Article Neurosurg Focus Video · July 2022 In this video, the authors highlight the operative treatment of a 55-year-old man with chronic osteomyelitis discitis. The operation entailed a minimally invasive lateral retroperitoneal transpsoas approach for L3 and L4 corpectomies, L2-5 interbody fusion ... Full text Open Access Link to item Cite

Predicting development of severe clinically relevant distal junctional kyphosis following adult cervical deformity surgery, with further distinction from mild asymptomatic episodes.

Journal Article J Neurosurg Spine · June 1, 2022 OBJECTIVE: This retrospective cohort study aimed to develop a formal predictive model distinguishing between symptomatic and asymptomatic distal junctional kyphosis (DJK). In this study the authors identified a DJK rate of 32.2%. Predictive models were cre ... Full text Open Access Link to item Cite

Are the Arbeitsgemeinschaft Für Osteosynthesefragen (AO) Principles for Long Bone Fractures Applicable to 3-Column Osteotomy to Reduce Rod Fracture Rates?

Journal Article Clin Spine Surg · June 1, 2022 OBJECTIVE: The aim was to determine whether applying Arbeitsgemeinschaft für Osteosynthesefragen (AO) principles for external fixation of long bone fracture to patients with a 3-column osteotomy (3CO) would be associated with reduced rod fracture (RF) rate ... Full text Open Access Link to item Cite

Radiographic Characteristics of Cervical Deformity (CD) Using a Discriminant Analysis: The Value of Extension Radiographs.

Journal Article Clin Spine Surg · June 1, 2022 STUDY DESIGN: This was a retrospective review of a prospectively collected database. OBJECTIVE: The aim of this study was to delineate radiographic parameters that distinguish severe cervical spine deformity (CSD). SUMMARY OF BACKGROUND DATA: Our objective ... Full text Open Access Link to item Cite

Perioperative Pain Management for Elective Spine Surgery: Opioid Use and Multimodal Strategies.

Journal Article World Neurosurg · June 2022 In recent years, physicians and institutions have come to recognize the increasing opioid epidemic in the United States, thus prompting a dramatic shift in opioid prescribing patterns. The lack of well-studied alternative treatment regimens has led to a su ... Full text Open Access Link to item Cite

Complication rate evolution across a 10-year enrollment period of a prospective multicenter database.

Journal Article J Neurosurg Spine · June 1, 2022 OBJECTIVE: Adult spinal deformity is a complex pathology that benefits greatly from surgical treatment. Despite continuous innovation, little is known regarding continuous changes in surgical techniques and the complications rate. The objective of the curr ... Full text Open Access Link to item Cite

The impact of lumbar alignment targets on mechanical complications after adult lumbar scoliosis surgery.

Journal Article Eur Spine J · June 2022 PURPOSE: The purpose of this study was to determine the discriminatory ability of age-adjusted alignment offset and the global alignment and proportion (GAP) score parameters to predict postoperative mechanical complications. METHODS: Surgical patients fro ... Full text Open Access Link to item Cite

Time trend analysis of database and registry use in the neurosurgical literature: evidence for the advance of registry science.

Journal Article J Neurosurg · June 1, 2022 Full text Open Access Link to item Cite

Revision Strategies for Harrington Rod Instrumentation: Radiographic Outcomes and Complications.

Journal Article Global Spine J · May 2022 STUDY DESIGN: Retrospective case series. OBJECTIVE: The purpose of this study is to evaluate the clinical and radiographic outcomes following revision surgery following Harrington rod instrumentation. METHODS: Patients who underwent revision surgery with a ... Full text Open Access Link to item Cite

Improvement and International Validation of the Predictive Probability of the Patient Demographics, Radiographic Index, and Surgical Invasiveness for Mechanical Failure (PRISM) Model for Preventive Procedures in Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · May 1, 2022 STUDY DESIGN: This is an international multicenter retrospective review of 219 surgically treated consecutive adult spinal deformity (ASD) patients who had a minimum of five fused segments, completed a 2-year follow-up. OBJECTIVE: The purpose of this study ... Full text Open Access Link to item Cite

Kickstand rods and correction of coronal malalignment in patients with adult spinal deformity.

Journal Article Eur Spine J · May 2022 PURPOSE: Coronal malalignment (CM) is a challenging spinal deformity to treat. The kickstand rod (KR) technique is powerful for correcting truncal shift. This study tested the hypothesis that the KR technique provides superior coronal alignment correction ... Full text Open Access Link to item Cite

Surgeons' risk perception in ASD surgery: The value of objective risk assessment on decision making and patient counselling.

Journal Article Eur Spine J · May 2022 BACKGROUND: Surgeons often rely on their intuition, experience and published data for surgical decision making and informed consent. Literature provides average values that do not allow for individualized assessments. Accurate validated machine learning (M ... Full text Open Access Link to item Cite

Two- and three-year outcomes of minimally invasive and hybrid correction of adult spinal deformity.

Journal Article J Neurosurg Spine · April 1, 2022 OBJECTIVE: Previous studies have demonstrated the short-term radiographic and clinical benefits of circumferential minimally invasive surgery (cMIS) and hybrid (i.e., minimally invasive anterior or lateral interbody fusion with an open posterior approach) ... Full text Open Access Link to item Cite

Image Quality and Dose Comparison of 3 Mobile Intraoperative Three-Dimensional Imaging Systems in Spine Surgery.

Journal Article World Neurosurg · April 2022 OBJECTIVE: To evaluate radiation exposure and image quality (IQ) for 3 intraoperative imaging systems (Airo TruCT, Cios Spin, O-arm) using varying radiation dose settings in a single cadaveric model. METHODS: Axial images of L4-5 instrumentation were obtai ... Full text Open Access Link to item Cite

Differences in Patient-Reported Outcomes Between Anterior and Posterior Approaches for Treatment of Cervical Spondylotic Myelopathy: A Quality Outcomes Database Analysis.

Journal Article World Neurosurg · April 2022 OBJECTIVE: Surgery for cervical spondylotic myelopathy (CSM) may use anterior or posterior approaches. Our objective was to compare baseline differences and validated postoperative patient-reported outcome measures between anterior and posterior approaches ... Full text Open Access Link to item Cite

When can we expect global sagittal alignment to reach a stable value following cervical deformity surgery?

Journal Article J Neurosurg Spine · April 1, 2022 OBJECTIVE: Cervical deformity (CD) is a complex condition with a clear impact on patient quality of life, which can be improved with surgical treatment. Previous study following thoracolumbar surgery demonstrated a spontaneous and maintained improvement in ... Full text Open Access Link to item Cite

Predictive Analytics for Determining Extended Operative Time in Corrective Adult Spinal Deformity Surgery.

Journal Article Int J Spine Surg · April 2022 BACKGROUND: More sophisticated surgical techniques for correcting adult spinal deformity (ASD) have increased operative times, adding to physiologic stress on patients and increased complication incidence. This study aims to determine factors associated wi ... Full text Open Access Link to item Cite

Comparing and Contrasting the Clinical Utility of Sagittal Spine Alignment Classification Frameworks: Roussouly Versus SRS-Schwab.

Journal Article Spine (Phila Pa 1976) · March 15, 2022 STUDY DESIGN: Retrospective cohort study of a prospectively collected database. OBJECTIVE: To compare clinical utility of two common classification systems for adult spinal deformity (ASD) and determine whether both should be considered in surgical plannin ... Full text Open Access Link to item Cite

Low-Density Pedicle Screw Constructs Are Associated with Lower Incidence of Proximal Junctional Failure in Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · March 15, 2022 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: Determine whether screws per level and rod material/diameter are associated with incidence of proximal junctional kyphosis (PJF). SUMMARY OF BACKGROUND DATA: PJF is a common and particularly adverse comp ... Full text Open Access Link to item Cite

Assessment of Adult Spinal Deformity Complication Timing and Impact on 2-Year Outcomes Using a Comprehensive Adult Spinal Deformity Classification System.

Journal Article Spine (Phila Pa 1976) · March 15, 2022 STUDY DESIGN: Retrospective review of prospectively collected multicenter registry data. OBJECTIVE: To identify rates and timing of postoperative complications in adult spinal deformity (ASD) patients, the impact of complication type and timing on health r ... Full text Open Access Link to item Cite

Reaching the medicare allowable threshold in adult spinal deformity surgery: multicenter cost analysis comparing actual direct hospital costs versus what the government will pay.

Journal Article Spine Deform · March 2022 STUDY DESIGN: Retrospective multicenter cost analysis. OBJECTIVE: To (1) determine if index episode of care (iEOC) costs of Adult Spinal Deformity (ASD) surgeries are below the Medicare Allowable (MA) threshold, and (2) identify variables that can predict ... Full text Open Access Link to item Cite

Opioid use prior to surgery is associated with worse preoperative and postoperative patient reported quality of life and decreased surgical cost effectiveness for symptomatic adult spine deformity; A matched cohort analysis.

Journal Article N Am Spine Soc J · March 2022 BACKGROUND: Preoperative opioid is associated with poor postoperative outcomes for several surgical specialties, including neurosurgical, orthopedic, and general surgery. Patients with symptomatic adult spinal deformity (SASD) are among the highest patient ... Full text Open Access Link to item Cite

Adult Spinal Deformity Surgery Is Associated with Increased Productivity and Decreased Absenteeism From Work and School.

Journal Article Spine (Phila Pa 1976) · February 15, 2022 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: We hypothesized that adult spinal deformity (ASD) surgery would be associated with improved work- and school-related productivity, as well as decreased rates of absenteeism. SUMMARY OF BACKGROUND DATA: A ... Full text Open Access Link to item Cite

Examination of Adult Spinal Deformity Patients Undergoing Surgery with Implanted Spinal Cord Stimulators and Intrathecal Pumps.

Journal Article Spine (Phila Pa 1976) · February 1, 2022 STUDY DESIGN: Retrospective cohort study of a prospectively collected multi-center database of adult spinal deformity (ASD) patients. OBJECTIVE: We hypothesized that patients undergoing ASD surgery with and without previous spinal cord stimulators (SCS)/ i ... Full text Open Access Link to item Cite

Patient outcomes after circumferential minimally invasive surgery compared with those of open correction for adult spinal deformity: initial analysis of prospectively collected data.

Journal Article J Neurosurg Spine · February 1, 2022 OBJECTIVE: Circumferential minimally invasive spine surgery (cMIS) for adult scoliosis has become more advanced and powerful, but direct comparison with traditional open correction using prospectively collected data is limited. The authors performed a retr ... Full text Open Access Link to item Cite

Does reduction of the Meyerding grade correlate with outcomes in patients undergoing decompression and fusion for grade I degenerative lumbar spondylolisthesis?

Journal Article J Neurosurg Spine · February 1, 2022 OBJECTIVE: Reduction of Meyerding grade is often performed during fusion for spondylolisthesis. Although radiographic appearance may improve, correlation with patient-reported outcomes (PROs) is rarely reported. In this study, the authors' aim was to asses ... Full text Open Access Link to item Cite

Quality metrics in adult spinal deformity surgery over the last decade: a combined analysis of the largest prospective multicenter data sets.

Journal Article J Neurosurg Spine · February 1, 2022 OBJECTIVE: The reported rate of complications and cost of adult spinal deformity (ASD) surgery, associated with an exponential increase in the number of surgeries, cause alarm among healthcare payers and providers worldwide. The authors conjointly analyzed ... Full text Open Access Link to item Cite

Posterior Cervical Decompression and Fusion With Exoscope: 2-Dimensional Operative Video.

Journal Article Oper Neurosurg (Hagerstown) · February 1, 2022 Posterior cervical decompression and fusion is an effective strategy for correction of cervical spondylotic myelopathy. Here, we highlight the operative treatment of a 63-yr-old man entailing a 4-level posterior cervical laminectomy and fusion, with the us ... Full text Open Access Link to item Cite

Surgical Factors and Treatment Severity for Perioperative Complications Predict Hospital Length of Stay in Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · January 15, 2022 STUDY DESIGN: Retrospective review of prospectively collected multicenter registry data. OBJECTIVE: The aim of this study was to determine whether surgical variables and complications as graded by treatment severity impact postoperative hospital length of ... Full text Open Access Link to item Cite

Increasing Cost Efficiency in Adult Spinal Deformity Surgery: Identifying Predictors of Lower Total Costs.

Journal Article Spine (Phila Pa 1976) · January 1, 2022 STUDY DESIGN: Retrospective study of a prospective multicenter database. OBJECTIVE: The purpose of this study was to identify predictors of lower total surgery costs at 3 years for adult spinal deformity (ASD) patients. SUMMARY OF BACKGROUND DATA: ASD surg ... Full text Open Access Link to item Cite

Sagittal age-adjusted score (SAAS) for adult spinal deformity (ASD) more effectively predicts surgical outcomes and proximal junctional kyphosis than previous classifications.

Journal Article Spine Deform · January 2022 BACKGROUND: Several methodologies have been proposed to determine ideal ASD sagittal spinopelvic alignment (SRS-Schwab classification) global alignment and proportion (GAP) score, patient age-adjusted alignment). A recent study revealed the ability and lim ... Full text Open Access Link to item Cite

Examination of the Economic Burden of Frailty in Patients With Adult Spinal Deformity Undergoing Surgical Intervention.

Journal Article Neurosurgery · January 1, 2022 BACKGROUND: With increasing interest in cost optimization, costs of adult spinal deformity (ASD) surgery intersections with frailty merit investigation. OBJECTIVE: To investigate costs associated with ASD and frailty. METHODS: Patients with ASD (scoliosis ... Full text Open Access Link to item Cite

Multi-institutional Analysis on Rate of Pseudarthrosis Following Anterior Cervical Discectomy and Fusion Using Allograft Cellular Bone Matrix (Osteocel)

Conference NEUROSURGERY · 2022 Cite

Assessing the Efficacy of the mJOA in Myelopathic Patients: A Cervical QOD Study

Conference NEUROSURGERY · 2022 Cite

Have We Made Temporal Advancements in Optimizing Surgical Outcomes and Recovery for High Risk Spinal Deformity Patients?

Conference NEUROSURGERY · 2022 Cite

Beyond Placement of Pedicle Screws - New Applications for Robotics in Spine Surgery: A Multi-Surgeon, Single-Institution Experience.

Journal Article Front Surg · 2022 Interest in robotic-assisted spine surgery has grown as surgeon comfort and technology has evolved to maximize benefits of time saving and precision. However, the Food and Drug Administration (FDA) has currently only approved robotics to assist in determin ... Full text Open Access Link to item Cite

Cervical deformity patients with baseline hyperlordosis or hyperkyphosis differ in surgical treatment and radiographic outcomes.

Journal Article J Craniovertebr Junction Spine · 2022 BACKGROUND: Patients with symptomatic cervical deformity (CD) requiring surgical correction often present with hyperkyphosis (HK), although patients with hyperlordotic curves may require surgery as well. Few studies have investigated differences in CD corr ... Full text Open Access Link to item Cite

Individual differences in postoperative recovery trajectories for adult symptomatic lumbar scoliosis

Journal Article JOURNAL OF NEUROSURGERY-SPINE · 2022 Full text Open Access Cite

Barriers to Early Surgery for Spinal Cord Injuries: A Report from the North American Clinical Trials Network for Spinal Cord Injury

Conference JOURNAL OF NEUROSURGERY · 2022 Cite

Multicenter assessment of outcomes and complications associated with transforaminal versus anterior lumbar interbody fusion for fractional curve correction.

Journal Article J Neurosurg Spine · December 1, 2021 OBJECTIVE: Few studies have compared fractional curve correction after long fusion between transforaminal lumbar interbody fusion (TLIF) and anterior lumbar interbody fusion (ALIF) for adult symptomatic thoracolumbar/lumbar scoliosis (ASLS). The objective ... Full text Open Access Link to item Cite

Orthopedic disease burden in adult patients with symptomatic lumbar scoliosis: results from a prospective multicenter study.

Journal Article J Neurosurg Spine · December 1, 2021 OBJECTIVE: Although the health impact of adult symptomatic lumbar scoliosis (ASLS) is substantial, these patients often have other orthopedic problems that have not been previously quantified. The objective of this study was to assess disease burden of oth ... Full text Open Access Link to item Cite

Global coronal decompensation and adult spinal deformity surgery: comparison of upper-thoracic versus lower-thoracic proximal fixation for long fusions.

Journal Article J Neurosurg Spine · December 1, 2021 OBJECTIVE: Deterioration of global coronal alignment (GCA) may be associated with worse outcomes after adult spinal deformity (ASD) surgery. The impact of fusion length and upper instrumented vertebra (UIV) selection on patients with this complication is u ... Full text Open Access Link to item Cite

Lateral Thoracolumbar Listhesis as an Independent Predictor of Disability in Adult Scoliosis Patients: Multivariable Assessment Before and After Surgical Realignment.

Journal Article Neurosurgery · November 18, 2021 BACKGROUND: Lateral (ie, coronal) vertebral listhesis may contribute to disability in adult scoliosis patients. OBJECTIVE: To assess for a correlation between lateral listhesis and disability among patients with adult scoliosis. METHODS: This was a retrosp ... Full text Open Access Link to item Cite

Classifying Patients Operated for Spondylolisthesis: A K-Means Clustering Analysis of Clinical Presentation Phenotypes.

Journal Article Neurosurgery · November 18, 2021 BACKGROUND: Trials of lumbar spondylolisthesis are difficult to compare because of the heterogeneity in the populations studied. OBJECTIVE: To define patterns of clinical presentation. METHODS: This is a study of the prospective Quality Outcomes Database s ... Full text Open Access Link to item Cite

Operative Treatment of Severe Scoliosis in Symptomatic Adults: Multicenter Assessment of Outcomes and Complications With Minimum 2-Year Follow-up.

Journal Article Neurosurgery · November 18, 2021 BACKGROUND: Few reports focus on adults with severe scoliosis. OBJECTIVE: To report surgical outcomes and complications for adults with severe scoliosis. METHODS: A multicenter, retrospective review was performed on operatively treated adults with severe s ... Full text Open Access Link to item Cite

A Novel Weave Tether Technique for Proximal Junctional Kyphosis Prevention in 71 Adult Spinal Deformity Patients: A Preliminary Case Series Assessing Early Complications and Efficacy.

Journal Article Oper Neurosurg (Hagerstown) · November 15, 2021 BACKGROUND: Proximal junctional kyphosis (PJK) rates may be as high as 69.4% after adult spinal deformity (ASD) surgery. PJK is one of the greatest unsolved challenges in long-segment fusions for ASD and remains a common indication for costly and impactful ... Full text Open Access Link to item Cite

Stratifying outcome based on the Oswestry Disability Index for operative treatment of adult spinal deformity on patients 60 years of age or older: a multicenter, multi-continental study on Prospective Evaluation of Elderly Deformity Surgery (PEEDS).

Journal Article Spine J · November 2021 BACKGROUND CONTEXT: Patients with adult spinal deformity suffer from disease related disability as measured by the Oswestry Disability Index (ODI) for which surgery can result in significant improvements. PURPOSE: The purpose of this study was to show the ... Full text Open Access Link to item Cite

The Scoli-RISK 1 results of lower extremity motor function 5 years after complex adult spinal deformity surgery.

Journal Article Eur Spine J · November 2021 INTRODUCTION: Neurologic complications after complex adult spinal deformity (ASD) surgery are important, yet outcomes are heterogeneously reported, and long-term follow-up of actual lower extremity motor function is unknown. OBJECTIVE: To prospectively eva ... Full text Open Access Link to item Cite

Appropriate Risk Stratification and Accounting for Age-Adjusted Reciprocal Changes in the Thoracolumbar Spine Reduces the Incidence and Magnitude of Distal Junctional Kyphosis in Cervical Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · November 1, 2021 STUDY DESIGN: Retrospective cohort study of a prospective cervical deformity (CD) database. OBJECTIVE: Identify factors associated with distal junctional kyphosis (DJK); assess differences across DJK types. SUMMARY OF BACKGROUND DATA: DJK may develop as co ... Full text Open Access Link to item Cite

Editorial. Training the next generation of spine surgeons: an orthopedic and neurosurgical collaboration with historical precedence.

Journal Article J Neurosurg Spine · November 1, 2021 Full text Open Access Link to item Cite

Surgical Strategy for the Management of Cervical Deformity Is Based on Type of Cervical Deformity.

Journal Article J Clin Med · October 21, 2021 OBJECTIVES: Cervical deformity morphotypes based on type and location of deformity have previously been described. This study aimed to examine the surgical strategies implemented to treat these deformity types and identify if differences in treatment strat ... Full text Open Access Link to item Cite

At What Point Should the Thoracolumbar Region Be Addressed in Patients Undergoing Corrective Cervical Deformity Surgery?

Journal Article Spine (Phila Pa 1976) · October 15, 2021 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: The aim of this study was to investigate the impact of cervical to thoracolumbar ratios on poor outcomes in cervical deformity (CD) corrective surgery. SUMMARY OF BACKGROUND DATA: Consideration of distal ... Full text Open Access Link to item Cite

Reduced occurrence of primary rod fracture after adult spinal deformity surgery with accessory supplemental rods: retrospective analysis of 114 patients with minimum 2-year follow-up.

Journal Article J Neurosurg Spine · October 1, 2021 OBJECTIVE: Rod fracture (RF) after adult spinal deformity (ASD) surgery is reported in approximately 6.8%-33% of patients and is associated with loss of deformity correction and higher reoperation rates. The authors' objective was to determine the effect o ... Full text Open Access Link to item Cite

Impact of predominant symptom location among patients undergoing cervical spine surgery on 12-month outcomes: an analysis from the Quality Outcomes Database.

Journal Article J Neurosurg Spine · October 1, 2021 OBJECTIVE: The impact of the type of pain presentation on outcomes of spine surgery remains elusive. The aim of this study was to assess the impact of predominant symptom location (predominant arm pain vs predominant neck pain vs equal neck and arm pain) o ... Full text Open Access Link to item Cite

Longitudinal Impact of Acute Spinal Cord Injury on Clinical Pharmacokinetics of Riluzole, a Potential Neuroprotective Agent.

Journal Article J Clin Pharmacol · September 2021 Riluzole, a benzothiazole sodium channel blocker that received US Food and Drug Administration approval to attenuate neurodegeneration in amyotrophic lateral sclerosis in 1995, was found to be safe and potentially efficacious in a spinal cord injury (SCI) ... Full text Open Access Link to item Cite

Predictors of serious, preventable, and costly medical complications in a population of adult spinal deformity patients.

Journal Article Spine J · September 2021 BACKGROUND CONTEXT: In 2008, the Centers for Medicare and Medicaid Services (CMS) established a list of hospital-acquired conditions (HACs) with significant deleterious effects on both patients and providers. Adult spinal deformity (ASD) surgery is complex ... Full text Open Access Link to item Cite

Prioritization of Realignment Associated With Superior Clinical Outcomes for Cervical Deformity Patients.

Journal Article Neurospine · September 2021 OBJECTIVE: To prioritize the cervical parameter targets for alignment. METHODS: Included: cervical deformity (CD) patients (C2-7 Cobb angle > 10°, cervical lordosis > 10°, cervical sagittal vertical axis [cSVA] > 4 cm, or chin-brow vertical angle > 25°) wi ... Full text Open Access Link to item Cite

Front-Back Cervical Deformity Correction by Anterior Cervical Discectomy and Fusion With Posterior Instrumentation: 2-Dimensional Operative Video.

Journal Article Oper Neurosurg (Hagerstown) · August 16, 2021 Front-back procedures for cervical deformity permit the correction of cervical kyphosis in the setting of unfused facets. Here, we highlight the operative treatment of a 65-yr-old female entailing a 4-level anterior cervical discectomy and fusion (ACDF) at ... Full text Open Access Link to item Cite

Outcomes of Surgical Treatment for 138 Patients With Severe Sagittal Deformity at a Minimum 2-Year Follow-up: A Case Series.

Journal Article Oper Neurosurg (Hagerstown) · August 16, 2021 BACKGROUND: Operative treatment of adult spinal deformity (ASD) can be very challenging with high complication rates. It is well established that patients benefit from such treatment; however, the surgical outcomes for patients with severe sagittal deformi ... Full text Open Access Link to item Cite

A Risk-Benefit Analysis of Increasing Surgical Invasiveness Relative to Frailty Status in Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · August 15, 2021 STUDY DESIGN: Retrospective review of a prospectively enrolled multicenter Adult Spinal Deformity (ASD) database. OBJECTIVE: Investigate invasiveness and outcomes of ASD surgery by frailty state. SUMMARY OF BACKGROUND DATA: The ASD Invasiveness Index incor ... Full text Open Access Link to item Cite

Does Achieving Global Spinal Alignment Lead to Higher Patient Satisfaction and Lower Disability in Adult Spinal Deformity?

Journal Article Spine (Phila Pa 1976) · August 15, 2021 STUDY DESIGN: Multicenter retrospective review of prospective database. OBJECTIVE: The aim of this study was to investigate potential associations between postoperative alignment and satisfaction. SUMMARY OF BACKGROUND DATA: Achieving high satisfaction is ... Full text Open Access Link to item Cite

Artificial intelligence clustering of adult spinal deformity sagittal plane morphology predicts surgical characteristics, alignment, and outcomes.

Journal Article Eur Spine J · August 2021 PURPOSE: AI algorithms have shown promise in medical image analysis. Previous studies of ASD clusters have analyzed alignment metrics-this study sought to complement these efforts by analyzing images of sagittal anatomical spinopelvic landmarks. We hypothe ... Full text Open Access Link to item Cite

Racial and Socioeconomic Minorities May Have Lower Quality of Life and Lower Chance of Returning to Work Following Surgery for Cervical Myelopathy: Analyses from the Quality Outcomes Database (QOD)

Conference JOURNAL OF NEUROSURGERY · August 2021 Link to item Cite

Posterior Polyethylene Tethers Reduce Occurrence of Proximal Junctional Kyphosis After Multilevel Spinal Instrumentation for Adult Spinal Deformity: A Retrospective Analysis.

Journal Article Neurosurgery · July 15, 2021 BACKGROUND: Proximal junctional kyphosis (PJK) is a common postoperative complication after adult spinal deformity (ASD) surgery and may manifest with neurological decline, worsening spinal deformity, and spinal instability, which warrant reoperation. Rate ... Full text Open Access Link to item Cite

Defining a Surgical Invasiveness Threshold for Increased Risk of a Major Complication Following Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · July 15, 2021 STUDY DESIGN: Retrospective review. OBJECTIVES: The aim of this study was to define a surgical invasiveness threshold that predicts major complications after adult spinal deformity (ASD) surgery; use this threshold to categorize patients into quartiles by ... Full text Open Access Link to item Cite

Patient-reported outcome improvements at 24-month follow-up after fusion added to decompression for grade I degenerative lumbar spondylolisthesis: a multicenter study using the Quality Outcomes Database.

Journal Article J Neurosurg Spine · July 1, 2021 OBJECTIVE: The ideal surgical management of grade I lumbar spondylolisthesis has not been determined despite extensive prior investigations. In this cohort study, the authors used data from the large, multicenter, prospectively collected Quality Outcomes D ... Full text Open Access Link to item Cite

Operative versus nonoperative treatment for adult symptomatic lumbar scoliosis at 5-year follow-up: durability of outcomes and impact of treatment-related serious adverse events.

Journal Article J Neurosurg Spine · July 1, 2021 OBJECTIVE: Although short-term adult symptomatic lumbar scoliosis (ASLS) studies favor operative over nonoperative treatment, longer outcomes are critical for assessment of treatment durability, especially for operative treatment, because the majority of i ... Full text Open Access Link to item Cite

Identifying patients at risk for nonroutine discharge after surgery for cervical myelopathy: an analysis from the Quality Outcomes Database.

Journal Article J Neurosurg Spine · July 1, 2021 OBJECTIVE: Optimizing patient discharge after surgery has been shown to impact patient recovery and hospital/physician workflow and to reduce healthcare costs. In the current study, the authors sought to identify risk factors for nonroutine discharge after ... Full text Open Access Link to item Cite

Improvement in some Ames-ISSG cervical deformity classification modifier grades may correlate with clinical improvement.

Journal Article J Clin Neurosci · July 2021 This retrospective cohort study describes adult cervical deformity(ACD) patients with Ames-ACD classification at baseline(BL) and 1-year post-operatively and assesses the relationship of improvement in Ames modifiers with clinical outcomes. Patients ≥ 18yr ... Full text Open Access Link to item Cite

Improvement in SRS-22R Self-Image Correlate Most with Patient Satisfaction after 3-Column Osteotomy.

Journal Article Spine (Phila Pa 1976) · June 15, 2021 STUDY DESIGN: Longitudinal cohort. OBJECTIVES: The aim of this study was to examine the relationship between patient satisfaction, patient-reported outcome measures (PROMs) and radiographic parameters in adult spine deformity (ASD) patients undergoing thre ... Full text Open Access Link to item Cite

"July Effect" Revisited: July Surgeries at Residency Training Programs are Associated with Equivalent Long-term Clinical Outcomes Following Lumbar Spondylolisthesis Surgery.

Journal Article Spine (Phila Pa 1976) · June 15, 2021 STUDY DESIGN: Retrospective analysis of a prospective registry. OBJECTIVE: We utilized the Quality Outcomes Database (QOD) registry to investigate the "July Effect" at QOD spondylolisthesis module sites with residency trainees. SUMMARY OF BACKGROUND DATA: ... Full text Open Access Link to item Cite

The Impact of Instrumentation and Implant Surface Technology on Cervical and Thoracolumbar Fusion.

Journal Article Oper Neurosurg (Hagerstown) · June 15, 2021 Spinal fusion has undergone significant evolution and improvement over the past 50 yr. Historically, spine fusion was noninstrumented and arthrodesis was based entirely on autograft. Improved understanding of spinal anatomy and materials science ushered in ... Full text Open Access Link to item Cite

Timing of conversion to cervical malalignment and proximal junctional kyphosis following surgical correction of adult spinal deformity: a 3-year radiographic analysis.

Journal Article J Neurosurg Spine · June 1, 2021 OBJECTIVE: The goal of this study was to assess the conversion rate from baseline cervical alignment to postoperative cervical deformity (CD) and the corresponding proximal junctional kyphosis (PJK) rate in patients undergoing thoracolumbar adult spinal de ... Full text Open Access Link to item Cite

Patient-related and radiographic predictors of inferior health-related quality-of-life measures in adult patients with nonoperative spinal deformity.

Journal Article J Neurosurg Spine · June 1, 2021 OBJECTIVE: Patients with nonoperative (N-Op) adult spinal deformity (ASD) have inferior long-term spinopelvic alignment and clinical outcomes. Predictors of lower quality-of-life measures in N-Op populations have yet to be sufficiently investigated. The ai ... Full text Open Access Link to item Cite

Impact of US hospital center and interhospital transfer on spinal cord injury management: An analysis of the National Trauma Data Bank.

Journal Article J Trauma Acute Care Surg · June 1, 2021 BACKGROUND: Traumatic spinal cord injury (SCI) is a serious public health problem. Outcomes are determined by severity of immediate injury, mitigation of secondary downstream effects, and rehabilitation. This study aimed to understand how the center type a ... Full text Open Access Link to item Cite

Use of rhBMP-2 for adult spinal deformity surgery: patterns of usage and changes over the past decade.

Journal Article Neurosurg Focus · June 2021 OBJECTIVE: Recombinant human bone morphogenetic protein-2 (rhBMP-2) has been shown to increase fusion rates; however, cost, limited FDA approval, and possible complications impact its use. Decisions regarding rhBMP-2 use and changes over time have not been ... Full text Open Access Link to item Cite

Pseudarthrosis rate following anterior cervical discectomy with fusion using an allograft cellular bone matrix: a multi-institutional analysis.

Journal Article Neurosurg Focus · June 2021 OBJECTIVE: The use of osteobiologics, engineered materials designed to promote bone healing by enhancing bone growth, is becoming increasingly common for spinal fusion procedures, but the efficacy of some of these products is unclear. The authors performed ... Full text Open Access Link to item Cite

Editorial. Anterior cervical fusion and rhBMP-2: a prospective study is needed to assess optimal dosing and delivery.

Journal Article Neurosurg Focus · June 2021 Full text Open Access Link to item Cite

Fractional Curve in Adult Spinal Deformity: Is it a Driver of or a Compensation for Coronal Malalignment?

Journal Article Clin Spine Surg · June 1, 2021 STUDY DESIGN: This was a retrospective review of the multicenter adult spine deformity database. OBJECTIVE: The objective of this study was to investigate the role of the fractional curve (FC) on global coronal malalignment. SUMMARY OF BACKGROUND DATA: Des ... Full text Open Access Link to item Cite

Introduction. Biologics in spine surgery.

Journal Article Neurosurg Focus · June 2021 Full text Open Access Link to item Cite

Trajectory-Based Classification of Recovery in Sensorimotor Complete Traumatic Cervical Spinal Cord Injury.

Journal Article Neurology · May 31, 2021 OBJECTIVE: To test the hypothesis that sensorimotor complete traumatic cervical spinal cord injury (SCI) is a heterogenous clinical entity comprising several subpopulations that follow fundamentally different trajectories of neurologic recovery. METHODS: W ... Full text Open Access Link to item Cite

Baseline Frailty Status Influences Recovery Patterns and Outcomes Following Alignment Correction of Cervical Deformity.

Journal Article Neurosurgery · May 13, 2021 BACKGROUND: Frailty severity may be an important determinant for impaired recovery after cervical spine deformity (CD) corrective surgery. OBJECTIVE: To evaluate postop clinical recovery among CD patients between frailty states undergoing primary procedure ... Full text Open Access Link to item Cite

Predictors of Superior Recovery Kinetics in Adult Cervical Deformity Correction: An Analysis Using a Novel Area Under the Curve Methodology.

Journal Article Spine (Phila Pa 1976) · May 1, 2021 STUDY DESIGN: Retrospective review of a prospective database. OBJECTIVE: The aim of this study was to identify demographic, surgical, and radiographic factors that predict superior recovery kinetics following cervical deformity (CD) corrective surgery. SUM ... Full text Open Access Link to item Cite

The minimally invasive interbody selection algorithm for spinal deformity.

Journal Article J Neurosurg Spine · May 1, 2021 OBJECTIVE: Minimally invasive surgery (MIS) for spinal deformity uses interbody techniques for correction, indirect decompression, and arthrodesis. Selection criteria for choosing a particular interbody approach are lacking. The authors created the minimal ... Full text Open Access Link to item Cite

A Comparison of Three Different Positioning Techniques on Surgical Corrections and Postoperative Alignment in Cervical Spinal Deformity (CD) Surgery.

Journal Article Spine (Phila Pa 1976) · May 1, 2021 STUDY DESIGN: Retrospective review of a prospective multicenter cervical deformity database. OBJECTIVE: To examine the differences in sagittal alignment correction between three positioning methods in cervical spinal deformity surgery (CD). SUMMARY OF BACK ... Full text Open Access Link to item Cite

Interhospital transfer status for spinal metastasis patients in the United States is associated with more severe clinical presentations and higher rates of inpatient complications.

Journal Article Neurosurg Focus · May 2021 OBJECTIVE: In patients with metastatic spinal disease (MSD), interhospital transfer can potentially impact clinical outcomes as the possible benefits of transferring a patient to a higher level of care must be weighed against the negative effects associate ... Full text Open Access Link to item Cite

Clinical characteristics and long-term outcomes for patients who undergo cytoreductive surgery for thoracic meningiomas: a retrospective analysis.

Journal Article Neurosurg Focus · May 2021 OBJECTIVE: Primary spinal meningiomas represent a rare indolent neoplasm usually situated in the intradural-extramedullary compartment. They have a predilection for afflicting the thoracic spine and most frequently present with sensory and/or motor symptom ... Full text Open Access Link to item Cite

Surgical outcomes in rigid versus flexible cervical deformities.

Journal Article J Neurosurg Spine · May 1, 2021 OBJECTIVE: Cervical deformity (CD) patients have severe disability and poor health status. However, little is known about how patients with rigid CD compare with those with flexible CD. The main objectives of this study were to 1) assess whether patients w ... Full text Open Access Link to item Cite

Impact of New Motor Deficit on HRQOL After Adult Spinal Deformity Surgery: Subanalysis From Scoli Risk 1 Prospective Study.

Journal Article Spine (Phila Pa 1976) · April 1, 2021 STUDY DESIGN: International, multicenter, prospective, longitudinal observational cohort. OBJECTIVE: To assess how new motor deficits affect patient reported quality of life scores after adult deformity surgery. SUMMARY OF BACKGROUND DATA: Adult spinal def ... Full text Open Access Link to item Cite

Depression Symptoms Are Associated with Poor Functional Status Among Operative Spinal Deformity Patients.

Journal Article Spine (Phila Pa 1976) · April 1, 2021 STUDY DESIGN: Retrospective review of prospective multicenter database. OBJECTIVE: The aim of this study was to investigate how preoperative mental status affects preoperative and postoperative disability and health scores in adult spinal deformity (ASD) p ... Full text Open Access Link to item Cite

Multicenter assessment of surgical outcomes in adult spinal deformity patients with severe global coronal malalignment: determination of target coronal realignment threshold.

Journal Article J Neurosurg Spine · March 1, 2021 OBJECTIVE: The impact of global coronal malalignment (GCM; C7 plumb line-midsacral offset) on adult spinal deformity (ASD) treatment outcomes is unclear. Here, the authors' primary objective was to assess surgical outcomes and complications in patients wit ... Full text Open Access Link to item Cite

Preoperative optimization for patients undergoing elective spine surgery.

Journal Article Clin Neurol Neurosurg · March 2021 Full text Open Access Link to item Cite

Factors influencing upper-most instrumented vertebrae selection in adult spinal deformity patients: qualitative case-based survey of deformity surgeons.

Journal Article J Spine Surg · March 2021 BACKGROUND: The decision upper-most instrumented vertebrae (UIV) in a multi-level fusion procedure can dramatically influence outcomes of corrective spine surgery. We aimed to create an algorithm for selection of UIV based on surgeon selection/reasoning of ... Full text Open Access Link to item Cite

Development and Validation of a Multidomain Surgical Complication Classification System for Adult Spinal Deformity.

Journal Article Spine (Phila Pa 1976) · February 15, 2021 STUDY DESIGN: Prospective analysis of example cases. OBJECTIVE: The aim of this study was to analyze the accuracy and repeatability of a new comprehensive classification system for capturing complications data in adult spinal deformity. SUMMARY OF BACKGROU ... Full text Open Access Link to item Cite

Practical answers to frequently asked questions for shared decision-making in adult spinal deformity surgery.

Journal Article J Neurosurg Spine · February 1, 2021 OBJECTIVE: The shared decision-making (SDM) process provides an opportunity to answer frequently asked questions (FAQs). The authors aimed to present a concise list of answers to FAQs to aid in SDM for adult spinal deformity (ASD) surgery. METHODS: From a ... Full text Open Access Link to item Cite

Safety and efficacy of riluzole in patients undergoing decompressive surgery for degenerative cervical myelopathy (CSM-Protect): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial.

Journal Article Lancet Neurol · February 2021 BACKGROUND: Degenerative cervical myelopathy represents the most common form of non-traumatic spinal cord injury. This trial investigated whether riluzole enhances outcomes in patients undergoing decompression surgery for degenerative cervical myelopathy. ... Full text Open Access Link to item Cite

Are Higher Global Alignment and Proportion Scores Associated With Increased Risks of Mechanical Complications After Adult Spinal Deformity Surgery? An External Validation.

Journal Article Clin Orthop Relat Res · February 1, 2021 BACKGROUND: The Global Alignment and Proportion (GAP) score, based on pelvic incidence-based proportional parameters, was recently developed to predict mechanical complications after surgery for spinal deformities in adults. However, this score has not bee ... Full text Open Access Link to item Cite

Measurement Properties of the Oswestry Disability Index in Recipients of Lumbar Spine Surgery.

Journal Article Spine (Phila Pa 1976) · January 15, 2021 STUDY DESIGN: This is an observational study on the measurement properties of the Oswestry Disability Index (ODI) version 1.0. OBJECTIVES: To (1) determine the construct validity of the tool, specifically structural validity; (2) analyze the criterion vali ... Full text Open Access Link to item Cite

Long-term impact of obesity on patient-reported outcomes and patient satisfaction after lumbar spine surgery: an observational study.

Journal Article J Neurosurg Spine · January 1, 2021 OBJECTIVE: Obese body habitus is a challenging issue to address in lumbar spine surgery. There is a lack of consensus on the long-term influence of BMI on patient-reported outcomes and satisfaction. This study aimed to examine the differences in patient-re ... Full text Open Access Link to item Cite

A single-center retrospective analysis of 3- or 4-level anterior cervical discectomy and fusion: surgical outcomes in 66 patients.

Journal Article J Neurosurg Spine · January 1, 2021 OBJECTIVE: Anterior cervical discectomy and fusion (ACDF) is a safe and effective intervention to treat cervical spine pathology. Although these were originally performed as single-level procedures, multilevel ACDF has been performed for patients with exte ... Full text Open Access Link to item Cite

Hematocrit as a predictor of preoperative transfusion-associated complications in spine surgery: A NSQIP study.

Journal Article Clin Neurol Neurosurg · January 2021 BACKGROUND CONTEXT: Preoperative optimization of medical comorbidities prior to spinal surgery is becoming an increasingly important intervention in decreasing postoperative complications and ensuring a satisfactory postoperative course. The treatment of p ... Full text Open Access Link to item Cite

Biomechanics, evaluation, and management of subaxial cervical spine injuries: A comprehensive review of the literature.

Journal Article J Clin Neurosci · January 2021 STUDY DESIGN: Literature review. OBJECTIVES: It has been reported that 2.4-3.7% of all blunt trauma victims suffer some element of cervical spine fracture, with the majority of these patients suffering from C3-7 (subaxial) involvement. With the improvement ... Full text Open Access Link to item Cite

Effect of age-adjusted alignment goals and distal inclination angle on the fate of distal junctional kyphosis in cervical deformity surgery.

Journal Article J Craniovertebr Junction Spine · 2021 BACKGROUND: Age-adjusted alignment targets in the context of distal junctional kyphosis (DJK) development have yet to be investigated. Our aim was to assess age-adjusted alignment targets, reciprocal changes, and role of lowest instrumented level orientati ... Full text Open Access Link to item Cite

The Influence of Unemployment and Disability Status on Clinical Outcomes in Patients Receiving Surgery for Low Back-Related Disorders: An Observational Study.

Journal Article Spine Surg Relat Res · 2021 INTRODUCTION: Employment status plays an essential role as a social determinant of health. Unemployed are more likely to have a longer length of hospital stay and a nearly twofold greater rate of 30 day readmission than those who were well employed at the ... Full text Open Access Link to item Cite

Redefining cervical spine deformity classification through novel cutoffs: An assessment of the relationship between radiographic parameters and functional neurological outcomes.

Journal Article J Craniovertebr Junction Spine · 2021 PURPOSE: The aim is to investigate the relationship between cervical parameters and the modified Japanese Orthopedic Association scale (mJOA). MATERIALS AND METHODS: Surgical adult cervical deformity (CD) patients were included in this retrospective analys ... Full text Open Access Link to item Cite

Racial and Socioeconomic Minorities May Have Lower Quality of Life and Lower Chance of Returning to Work Following Surgery for Cervical Myelopathy: Analyses from the Quality Outcomes Database (QOD)

Conference JOURNAL OF NEUROSURGERY · 2021 Cite

Predictive model for achieving good clinical and radiographic outcomes at one-year following surgical correction of adult cervical deformity.

Journal Article J Craniovertebr Junction Spine · 2021 BACKGROUND: For cervical deformity (CD) surgery, goals include realignment, improved patient quality of life, and improved clinical outcomes. There is limited research identifying patients most likely to achieve all three. OBJECTIVE: The objective is to cr ... Full text Open Access Link to item Cite

Prioritization of realignment associated with superior clinical outcomes for surgical cervical deformity patients.

Journal Article J Craniovertebr Junction Spine · 2021 BACKGROUND: To optimize quality of life in patients with cervical deformity (CD), there may be alignment targets to be prioritized. OBJECTIVE: To prioritize the cervical parameter targets for alignment. METHODS: Included: CD patients (C2-C7 Cobb >10°°, C2- ... Full text Open Access Link to item Cite

Cervical deformity patients with baseline hyperlordosis or hyperkyphosis differ in surgical treatment and radiographic outcomes.

Journal Article J Craniovertebr Junction Spine · 2021 INTRODUCTION: Patients with symptomatic cervical deformity (CD) requiring surgical correction often present with hyperkyphosis (HK), though patients with hyperlordotic curves may require surgery as well. Few studies have investigated differences in CD-corr ... Full text Open Access Link to item Cite

Risk-benefit assessment of major versus minor osteotomies for flexible and rigid cervical deformity correction.

Journal Article J Craniovertebr Junction Spine · 2021 INTRODUCTION: Osteotomies are commonly performed to correct sagittal malalignment in cervical deformity (CD). However, the risks and benefits of performing a major osteotomy for cervical deformity correction have been understudied. The objective of this re ... Full text Open Access Link to item Cite

Management of Acute Traumatic Spinal Cord Injury: A Review of the Literature.

Journal Article Front Surg · 2021 Traumatic spinal cord injury (TSCI) is a debilitating disease that poses significant functional and economic burden on both the individual and societal levels. Prognosis is dependent on the extent of the spinal injury and the severity of neurological dysfu ... Full text Open Access Link to item Cite

The impact of postoperative neurologic complications on recovery kinetics in cervical deformity surgery.

Journal Article J Craniovertebr Junction Spine · 2021 OBJECTIVE: The objective of the study is to investigate which neurologic complications affect clinical outcomes the most following cervical deformity (CD) surgery. METHODS: CD patients (C2-C7 Cobb >10°, CL >10°, cSVA >4 cm or chin-brow vertical angle >25°) ... Full text Open Access Link to item Cite

Pedicle Subtraction Osteotomy

Chapter · January 1, 2021 Patients with spinal malalignment may present with disabling back pain, increased fatigue, difficulty maintaining an erect posture, and reduced health-related quality of life (HRQL). The etiopathogenesis of curve progression with ensuing spinal malalignmen ... Full text Cite

A Radiographic Analysis of Lumbar Fusion Status and Instrumentation Failure After Complex Adult Spinal Deformity Surgery With Spinopelvic Fixation: Two-Year Follow-up From the Scoli-Risk-1 Prospective Database.

Journal Article Clin Spine Surg · December 2020 STUDY DESIGN: A retrospective review of prospectively collected data. OBJECTIVE: The objective of this study was to investigate the fusion status of the lumbar spine and lumbosacral junction at 2 years postoperatively after complex adult spinal deformity ( ... Full text Open Access Link to item Cite

Cost-effectiveness of adult lumbar scoliosis surgery: an as-treated analysis from the adult symptomatic scoliosis surgery trial with 5-year follow-up.

Journal Article Spine Deform · December 2020 STUDY DESIGN: Longitudinal comparative cohort. OBJECTIVE: The purpose of this study is to report on the cost-effectiveness of surgical versus non-surgical treatment for Adult Symptomatic Lumbar Scoliosis (ASLS) using the as-treated data and provide a compa ... Full text Open Access Link to item Cite

Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis.

Journal Article Neurospine · December 2020 OBJECTIVE: This was a retrospective, cohort study investigating the efficacy and safety of continuous low-dose postoperative tranexamic acid (PTXA) on drain output and transfusion requirements following adult spinal deformity surgery. METHODS: One hundred ... Full text Open Access Link to item Cite

Predictors of the Best Outcomes Following Minimally Invasive Surgery for Grade 1 Degenerative Lumbar Spondylolisthesis.

Journal Article Neurosurgery · November 16, 2020 BACKGROUND: The factors driving the best outcomes following minimally invasive surgery (MIS) for grade 1 degenerative lumbar spondylolisthesis are not clearly elucidated. OBJECTIVE: To investigate the factors that drive the best 24-mo patient-reported outc ... Full text Open Access Link to item Cite

Development and Validation of Cervical Prediction Models for Patient-Reported Outcomes at 1 Year After Cervical Spine Surgery for Radiculopathy and Myelopathy.

Journal Article Spine (Phila Pa 1976) · November 15, 2020 STUDY DESIGN: Retrospective analysis of prospectively collected registry data. OBJECTIVE: To develop and validate prediction models for 12-month patient-reported outcomes of disability, pain, and myelopathy in patients undergoing elective cervical spine su ... Full text Open Access Link to item Cite

Assessing the differences in characteristics of patients lost to follow-up at 2 years: results from the Quality Outcomes Database study on outcomes of surgery for grade I spondylolisthesis.

Journal Article J Neurosurg Spine · November 1, 2020 OBJECTIVE: Loss to follow-up has been shown to bias outcomes assessment among studies utilizing clinical registries. Here, the authors analyzed patients enrolled in a national surgical registry and compared the baseline characteristics of patients captured ... Full text Open Access Link to item Cite

Prospective multicenter assessment of complication rates associated with adult cervical deformity surgery in 133 patients with minimum 1-year follow-up.

Journal Article J Neurosurg Spine · November 1, 2020 OBJECTIVE: Although surgical treatment can provide significant improvement of symptomatic adult cervical spine deformity (ACSD), few reports have focused on the associated complications. The objective of this study was to assess complication rates at a min ... Full text Open Access Link to item Cite

Factors affecting approach selection for minimally invasive versus open surgery in the treatment of adult spinal deformity: analysis of a prospective, nonrandomized multicenter study.

Journal Article J Neurosurg Spine · November 1, 2020 OBJECTIVE: Surgical decision-making and planning is a key factor in optimizing outcomes in adult spinal deformity (ASD). Minimally invasive spinal (MIS) strategies for ASD have been increasingly used as an option to decrease postoperative morbidity. This s ... Full text Open Access Link to item Cite

The medicolegal impact of misplaced pedicle and lateral mass screws on spine surgery in the United States.

Journal Article Neurosurg Focus · November 2020 Spine surgery has been disproportionately impacted by medical liability and malpractice litigation, with the majority of claims and payouts related to procedural error. One common area for the potential avoidance of malpractice claims and subsequent payout ... Full text Open Access Link to item Cite

Impact of Dominant Symptom on 12-Month Patient-Reported Outcomes for Patients Undergoing Lumbar Spine Surgery.

Journal Article Neurosurgery · October 15, 2020 BACKGROUND: The impact of symptom characteristics on outcomes of spine surgery remains elusive. OBJECTIVE: To determine the impact of symptom location, severity, and duration on outcomes following lumbar spine surgery. METHODS: We queried the Quality Outco ... Full text Open Access Link to item Cite

Risk Factor Analysis for Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery: A New Simple Scoring System to Identify High-Risk Patients.

Journal Article Global Spine J · October 2020 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: Develop a simple scoring system to estimate proximal junctional kyphosis (PJK) risk. METHODS: A total of 417 adult spinal deformity (ASD) patients (80% females, 57.8 years) with 2-year follow-up were inc ... Full text Open Access Link to item Cite

Patients with a depressive and/or anxiety disorder can achieve optimum Long term outcomes after surgery for grade 1 spondylolisthesis: Analysis from the quality outcomes database (QOD).

Journal Article Clin Neurol Neurosurg · October 2020 INTRODUCTION: In the current study, we sought to compare baseline demographic, clinical, and operative characteristics, as well as baseline and follow-up patient reported outcomes (PROs) of patients with any depressive and/or anxiety disorder undergoing su ... Full text Open Access Link to item Cite

Coronal Correction Using Kickstand Rods for Adult Thoracolumbar/Lumbar Scoliosis: Case Series With Analysis of Early Outcomes and Complications.

Journal Article Oper Neurosurg (Hagerstown) · September 15, 2020 BACKGROUND: The "kickstand rod technique" has been recently described for achieving and maintaining coronal correction in adult spinal deformity (ASD). Kickstand rods span scoliotic lumbar spine from the thoracolumbar junction proximally to a "kickstand il ... Full text Open Access Link to item Cite

Lower Satisfaction After Adult Spinal Deformity Surgery in Japan Than in the United States Despite Similar SRS-22 Pain and Function Scores: A Propensity-Score Matched Analysis.

Journal Article Spine (Phila Pa 1976) · September 1, 2020 STUDY DESIGN: A multicenter retrospective case series. OBJECTIVE: The purpose of this study was to compare the clinical outcomes of a surgical treatment for adult spinal deformity (ASD) in the United States (US) with those in Japan (JP) in a matched cohort ... Full text Open Access Link to item Cite

Cost-effectiveness of surgical treatment of adult spinal deformity: comparison of posterior-only versus anteroposterior approach.

Journal Article Spine J · September 2020 BACKGROUND CONTEXT: Considerable debate exists regarding the optimal surgical approach for adult spinal deformity (ASD). It remains unclear which approach, posterior-only or combined anterior-posterior (AP), is more cost-effective. Our goal is to determine ... Full text Open Access Link to item Cite

Open versus minimally invasive decompression for low-grade spondylolisthesis: analysis from the Quality Outcomes Database.

Journal Article J Neurosurg Spine · September 1, 2020 OBJECTIVE: Lumbar decompression without arthrodesis remains a potential treatment option for cases of low-grade spondylolisthesis (i.e., Meyerding grade I). Minimally invasive surgery (MIS) techniques have recently been increasingly used because of their t ... Full text Open Access Link to item Cite

Artificial Intelligence Models Predict Operative Versus Nonoperative Management of Patients with Adult Spinal Deformity with 86% Accuracy.

Journal Article World Neurosurg · September 2020 OBJECTIVE: Patients with ASD show complex and highly variable disease. The decision to manage patients operatively is largely subjective and varies based on surgeon training and experience. We sought to develop models capable of accurately discriminating b ... Full text Open Access Link to item Cite

A Comparison of Minimally Invasive and Open Transforaminal Lumbar Interbody Fusion for Grade 1 Degenerative Lumbar Spondylolisthesis: An Analysis of the Prospective Quality Outcomes Database.

Journal Article Neurosurgery · September 1, 2020 BACKGROUND: It remains unclear if minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) is comparable to traditional, open TLIF because of the limitations of the prior small-sample-size, single-center studies reporting comparative effectivene ... Full text Open Access Link to item Cite

The spino-pelvic ratio: a novel global sagittal parameter associated with clinical outcomes in adult spinal deformity patients.

Journal Article Eur Spine J · September 2020 PURPOSE: Analysis of interactions of spinal alignment metrics may uncover novel alignment parameters, similar to PI-LL. This study utilized a data-driven approach to hypothesis generation by testing all possible division interactions between spinal alignme ... Full text Open Access Link to item Cite

Counseling Guidelines for Anticipated Postsurgical Improvements in Pain, Function, Mental Health, and Self-image for Different Types of Adult Spinal Deformity.

Journal Article Spine (Phila Pa 1976) · August 15, 2020 STUDY DESIGN: Retrospective analysis of a multicenter prospective adult spinal deformity (ASD) database. OBJECTIVE: Quantify postoperative improvements in pain, function, mental health, and self-image for different ASD types. SUMMARY OF BACKGROUND DATA: Me ... Full text Open Access Link to item Cite

Kickstand Rod Technique for Correcting Coronal Imbalance in Adult Scoliosis: 2-Dimensional Operative Video.

Journal Article Oper Neurosurg (Hagerstown) · August 1, 2020 Restoration of spinal alignment and balance is a major goal of adult scoliosis surgery. In the past, sagittal alignment has been emphasized and was shown to have the greatest impact on functional outcomes. However, recent evidence suggests the impact of co ... Full text Open Access Link to item Cite

Sexual Dysfunction: Prevalence and Prognosis in Patients Operated for Degenerative Lumbar Spondylolisthesis.

Journal Article Neurosurgery · August 1, 2020 BACKGROUND: There is a paucity of investigation on the impact of spondylolisthesis surgery on back pain-related sexual inactivity. OBJECTIVE: To investigate predictors of improved sex life postoperatively by utilizing the prospective Quality Outcomes Datab ... Full text Open Access Link to item Cite

Intraoperative alignment goals for distinctive sagittal morphotypes of severe cervical deformity to achieve optimal improvements in health-related quality of life measures.

Journal Article Spine J · August 2020 BACKGROUND CONTEXT: Patients with severe cervical deformity (CD) often have profound deficits in numerous activities of daily living. The association between health status and postoperative radiographic goals is difficult to quantify. PURPOSE: We aimed to ... Full text Open Access Link to item Cite

Sacral insufficiency fractures after lumbosacral arthrodesis: salvage lumbopelvic fixation and a proposed management algorithm.

Journal Article J Neurosurg Spine · August 1, 2020 OBJECTIVE: Sacral insufficiency fracture after lumbosacral (LS) arthrodesis is an uncommon complication. The objective of this study was to report the authors' operative experience managing this complication, review pertinent literature, and propose a trea ... Full text Open Access Link to item Cite

Probability of severe frailty development among operative and nonoperative adult spinal deformity patients: an actuarial survivorship analysis over a 3-year period.

Journal Article Spine J · August 2020 BACKGROUND: Little is known of how frailty, a dynamic measure of physiological age, progresses relative to age or disability status. Operative treatment of adult spinal deformity (ASD) may play a role in frailty remediation and maintenance. PURPOSE: Compar ... Full text Open Access Link to item Cite

Deformity Correction Through the Use of Reduction Towers: 2-Dimensional Operative Video.

Journal Article Oper Neurosurg (Hagerstown) · August 1, 2020 Spinal deformity management can be difficult. The decision for surgery, approach, number of levels, and surgical technique all present challenges. Even when other issues are managed appropriately the process of how to correct the deformity needs special co ... Full text Open Access Link to item Cite

Outcomes and Complications With Age in Spondylolisthesis: An Evaluation of the Elderly From the Quality Outcomes Database.

Journal Article Spine (Phila Pa 1976) · July 15, 2020 STUDY DESIGN: Prospective database analysis. OBJECTIVE: To assess the effect of age on patient-reported outcomes (PROs) and complication rates after surgical treatment for spondylolisthesis SUMMARY OF BACKGROUND DATA.: Degenerative lumbar spondylolisthesis ... Full text Open Access Link to item Cite

Cost-Utility Analysis of rhBMP-2 Use in Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · July 15, 2020 STUDY DESIGN: Economic modeling of data from a multicenter, prospective registry. OBJECTIVE: The aim of this study was to analyze the cost utility of recombinant human bone morphogenetic protein-2 (BMP) in adult spinal deformity (ASD) surgery. SUMMARY OF B ... Full text Open Access Link to item Cite

Letter to the Editor. Education and evidence-based medicine in neurosurgery.

Journal Article J Neurosurg Spine · July 1, 2020 Full text Open Access Link to item Cite

Assessment of Patient Outcomes and Proximal Junctional Failure Rate of Patients with Adult Spinal Deformity Undergoing Caudal Extension of Previous Spinal Fusion.

Journal Article World Neurosurg · July 2020 OBJECTIVE: This case series examined patients undergoing caudal extension of prior fusion without alteration of the prior upper instrumented vertebra (UIV) to assess patient outcomes and rates of proximal junctional kyphosis (PJK)/proximal junctional failu ... Full text Open Access Link to item Cite

Sexual Dysfunction Secondary to Lumbar Stiffness in Adult Spinal Deformity Patients Before and After Long-Segment Spinal Fusion.

Journal Article World Neurosurg · July 2020 OBJECTIVE: Sexual function is an important factor contributing to quality of life. Adult spinal deformity (ASD) patients may have sexual limitations due to lumbar spinal stiffness that may be affected by long-segment fusion. METHODS: This study utilized a ... Full text Open Access Link to item Cite

Neuroanesthesia Guidelines for Optimizing Transcranial Motor Evoked Potential Neuromonitoring During Deformity and Complex Spinal Surgery: A Delphi Consensus Study.

Journal Article Spine (Phila Pa 1976) · July 1, 2020 STUDY DESIGN: Expert opinion-modified Delphi study. OBJECTIVE: We used a modified Delphi approach to obtain consensus among leading spinal deformity surgeons and their neuroanesthesiology teams regarding optimal practices for obtaining reliable motor evoke ... Full text Open Access Link to item Cite

Group-based Trajectory Modeling: A Novel Approach to Classifying Discriminative Functional Status Following Adult Spinal Deformity Surgery: Study of a 3-year Follow-up Group.

Journal Article Spine (Phila Pa 1976) · July 1, 2020 STUDY DESIGN: Retrospective review of prospectively collected database. OBJECTIVE: To delineate and visualize trajectories of the functional status in surgically-treated adult spinal deformity (ASD) patients. SUMMARY OF BACKGROUND DATA: Classifying long-te ... Full text Open Access Link to item Cite

Trajectory of Improvement in Myelopathic Symptoms From 3 to 12 Months Following Surgery for Degenerative Cervical Myelopathy.

Journal Article Neurosurgery · June 1, 2020 BACKGROUND: Degenerative cervical myelopathy (DCM) is a progressive disease resulting from cervical cord compression. The modified Japanese Orthopaedic Association (mJOA) is commonly used to grade myelopathic symptoms, but its persistent postoperative impr ... Full text Open Access Link to item Cite

Mini-Open Lateral Corpectomy for Thoracolumbar Junction Lesions.

Journal Article Oper Neurosurg (Hagerstown) · June 1, 2020 BACKGROUND: Neoplastic, traumatic, infectious, and degenerative pathologies affecting the thoracolumbar junction pose a unique challenge to spine surgeons. Posterior or anterior approaches have traditionally been utilized to treat these lesions. Although m ... Full text Open Access Link to item Cite

Intermediate-term clinical and radiographic outcomes with less invasive adult spinal deformity surgery: patients with a minimum follow-up of 4 years.

Journal Article Acta Neurochir (Wien) · June 2020 BACKGROUND: Little information exists regarding longer-term outcomes with minimally invasive spine surgery (MISS), particularly regarding long-segment and deformity procedures. We aimed to evaluate intermediate-term outcomes of MISS for adult spinal deform ... Full text Open Access Link to item Cite

The Influence of Surgical Intervention and Sagittal Alignment on Frailty in Adult Cervical Deformity.

Journal Article Oper Neurosurg (Hagerstown) · June 1, 2020 BACKGROUND: Frailty is a relatively new area of study for patients with cervical deformity (CD). As of yet, little is known of how operative intervention influences frailty status for patients with CD. OBJECTIVE: To investigate drivers of postoperative fra ... Full text Open Access Link to item Cite

Does Neck Disability Index Correlate With 12-Month Satisfaction After Elective Surgery for Cervical Radiculopathy? Results From a National Spine Registry.

Journal Article Neurosurgery · May 1, 2020 BACKGROUND: Modern healthcare reforms focus on identifying and measuring the quality and value of care. Patient satisfaction is particularly important in the management of degenerative cervical radiculopathy (DCR) since it leads to significant neck pain an ... Full text Open Access Link to item Cite

Minimally Invasive Spinal Deformity Surgery: Analysis of Patients Who Fail to Reach Minimal Clinically Important Difference.

Journal Article World Neurosurg · May 2020 BACKGROUND: It is well known that clinical improvements following surgical intervention are variable. While all surgeons strive to maximize reliability and degree of improvement, certain patients will fail to achieve meaningful gains. We aim to analyze pat ... Full text Open Access Link to item Cite

Quality Outcomes Database Spine Care Project 2012-2020: milestones achieved in a collaborative North American outcomes registry to advance value-based spine care and evolution to the American Spine Registry.

Journal Article Neurosurg Focus · May 1, 2020 The Quality Outcomes Database (QOD), formerly known as the National Neurosurgery Quality Outcomes Database (N2QOD), was established by the NeuroPoint Alliance (NPA) in collaboration with relevant national stakeholders and experts. The overarching goal of t ... Full text Open Access Link to item Cite

Correlation of return to work with patient satisfaction after surgery for lumbar spondylolisthesis: an analysis of the Quality Outcomes Database.

Journal Article Neurosurg Focus · May 1, 2020 OBJECTIVE: Return to work (RTW) and satisfaction are important outcome measures after surgery for degenerative spine disease. The authors queried the prospective Quality Outcomes Database (QOD) to determine if RTW correlated with patient satisfaction. METH ... Full text Open Access Link to item Cite

Does Patient Frailty Status Influence Recovery Following Spinal Fusion for Adult Spinal Deformity?: An Analysis of Patients With 3-Year Follow-up.

Journal Article Spine (Phila Pa 1976) · April 1, 2020 STUDY DESIGN: Retrospective review of a prospective database. OBJECTIVE: The aim of this study was to evaluate postop clinical recovery among adult spinal deformity (ASD) patients between frailty states undergoing primary procedures SUMMARY OF BACKGROUND D ... Full text Open Access Link to item Cite

Predictors of nonroutine discharge among patients undergoing surgery for grade I spondylolisthesis: insights from the Quality Outcomes Database.

Journal Article J Neurosurg Spine · April 1, 2020 OBJECTIVE: Discharge to an inpatient rehabilitation facility or another acute-care facility not only constitutes a postoperative challenge for patients and their care team but also contributes significantly to healthcare costs. In this era of changing dyna ... Full text Open Access Link to item Cite

Upper-thoracic versus lower-thoracic upper instrumented vertebra in adult spinal deformity patients undergoing fusion to the pelvis: surgical decision-making and patient outcomes.

Journal Article J Neurosurg Spine · April 1, 2020 OBJECTIVE: Optimal patient selection for upper-thoracic (UT) versus lower-thoracic (LT) fusion during adult spinal deformity (ASD) correction is challenging. Radiographic and clinical outcomes following UT versus LT fusion remain incompletely understood. T ... Full text Open Access Link to item Cite

Validation of the recently developed Total Disability Index: a single measure of disability in neck and back pain patients.

Journal Article J Neurosurg Spine · April 1, 2020 OBJECTIVE: Neck and back pain are highly prevalent conditions that account for major disability. The Neck Disability Index (NDI) and Oswestry Disability Index (ODI) are the two most common functional status measures for neck and back pain. However, no sing ... Full text Open Access Link to item Cite

Multicenter Prospective Assessment of Outcomes and Complications Associated with Severe Adult Scoliosis Surgery in 146 Patients with Minimum 2-Year Follow-up

Conference JOURNAL OF NEUROSURGERY · April 1, 2020 Link to item Cite

Team Approach: Safety and Value in the Practice of Complex Adult Spinal Surgery.

Journal Article JBJS Rev · April 2020 Surgical management of complex adult spinal deformities is of high risk, with a substantial risk of operative mortality. Current evidence shows that potential risk and morbidity resulting from surgery for complex spinal deformity may be minimized through r ... Full text Open Access Link to item Cite

Correction to: Natural History, Predictors of Outcome, and Effects of Treatment in Thoracic Spinal Cord Injury: A Multi-Center Cohort Study from the North American Clinical Trials Network by Wilson, J.R. et al. J. Neurotrauma 2018;35(21):2554–2560. (DOI: 10.1089/neu.2017.5535)

Journal Article Journal of Neurotrauma · March 15, 2020 Full text Open Access Cite

Effect modifiers for patient-reported outcomes in operatively and nonoperatively treated patients with adult symptomatic lumbar scoliosis: a combined analysis of randomized and observational cohorts.

Journal Article J Neurosurg Spine · March 6, 2020 OBJECTIVE: Adult symptomatic lumbar scoliosis (ASLS) is a common and disabling condition. The ASLS-1 was a multicenter, dual-arm study (with randomized and observational cohorts) examining operative and nonoperative care on health-related quality of life i ... Full text Open Access Link to item Cite

Utilization of Predictive Modeling to Determine Episode of Care Costs and to Accurately Identify Catastrophic Cost Nonwarranty Outlier Patients in Adult Spinal Deformity Surgery: A Step Toward Bundled Payments and Risk Sharing.

Journal Article Spine (Phila Pa 1976) · March 1, 2020 STUDY DESIGN: Retrospective review of prospectively-collected, multicenter adult spinal deformity (ASD) database. OBJECTIVE: The aim of this study was to evaluate the rate of patients who accrue catastrophic cost (CC) with ASD surgery utilizing direct, act ... Full text Open Access Link to item Cite

The morphology of cervical deformities: a two-step cluster analysis to identify cervical deformity patterns.

Journal Article J Neurosurg Spine · March 1, 2020 OBJECTIVE: Cervical deformity (CD) is difficult to define due to the high variability in normal cervical alignment based on postural- and thoracolumbar-driven changes to cervical alignment. The purpose of this study was to identify whether patterns of sagi ... Full text Open Access Link to item Cite

A New Piece of the Puzzle to Understand Cervical Sagittal Alignment: Utilizing a Novel Angle δ to Describe the Relationship among T1 Vertebral Body Slope, Cervical Lordosis, and Cervical Sagittal Alignment.

Journal Article Neurosurgery · March 1, 2020 Cervical alignment has become increasingly important in the planning of spine surgery. A relationship between the slope of T1 (T1S), the cervical lordosis (CL), and the overall cervical sagittal vertical axis (cSVA) has previously been demonstrated, but th ... Full text Open Access Link to item Cite

Effective Prevention of Proximal Junctional Failure in Adult Spinal Deformity Surgery Requires a Combination of Surgical Implant Prophylaxis and Avoidance of Sagittal Alignment Overcorrection.

Journal Article Spine (Phila Pa 1976) · February 15, 2020 STUDY DESIGN: Propensity score matched analysis of a multi-center prospective adult spinal deformity (ASD) database. OBJECTIVE: Evaluate if surgical implant prophylaxis combined with avoidance of sagittal overcorrection more effectively prevents proximal j ... Full text Open Access Link to item Cite

Should Sagittal Spinal Alignment Targets for Adult Spinal Deformity Correction Depend on Pelvic Incidence and Age?

Journal Article Spine (Phila Pa 1976) · February 15, 2020 STUDY DESIGN: Retrospective analysis. OBJECTIVE: Determine whether deformity corrections should vary by pelvic incidence (PI). SUMMARY OF BACKGROUND DATA: Alignment targets for deformity correction have been reported for various radiographic parameters. Th ... Full text Open Access Link to item Cite

The Importance of C2 Slope, a Singular Marker of Cervical Deformity, Correlates With Patient-reported Outcomes.

Journal Article Spine (Phila Pa 1976) · February 1, 2020 STUDY DESIGN: Retrospective review of a prospectively collected database. OBJECTIVE: To define a simplified singular measure of cervical deformity (CD), C2 slope (C2S), which correlates with postoperative outcomes. SUMMARY OF BACKGROUND DATA: Sagittal mala ... Full text Open Access Link to item Cite

The MISDEF2 algorithm: an updated algorithm for patient selection in minimally invasive deformity surgery.

Journal Article J Neurosurg Spine · February 1, 2020 OBJECTIVE: Minimally invasive surgery (MIS) can be used as an alternative or adjunct to traditional open techniques for the treatment of patients with adult spinal deformity. Recent advances in MIS techniques, including advanced anterior approaches, have i ... Full text Open Access Link to item Cite

Cervical, Thoracic, and Spinopelvic Compensation After Proximal Junctional Kyphosis (PJK): Does Location of PJK Matter?

Journal Article Global Spine J · February 2020 STUDY DESIGN: Retrospective case series. OBJECTIVE: Compensatory changes above a proximal junctional kyphosis (PJK) have not been defined. Understanding these mechanisms may help determine optimal level selection when performing revision for PJK. This stud ... Full text Open Access Link to item Cite

Durability of Satisfactory Functional Outcomes Following Surgical Adult Spinal Deformity Correction: A 3-Year Survivorship Analysis.

Journal Article Oper Neurosurg (Hagerstown) · February 1, 2020 BACKGROUND: Despite reports showing positive long-term functional outcomes following adult spinal deformity (ASD)-corrective surgery, it is unclear which factors affect the durability of these outcomes. OBJECTIVE: To assess durability of functional gains f ... Full text Open Access Link to item Cite

Fatty infiltration of the cervical extensor musculature, cervical sagittal balance, and clinical outcomes: An analysis of operative adult cervical deformity patients.

Journal Article J Clin Neurosci · February 2020 PURPOSE: To assess preliminary associations between fatty-infiltration (FI) of cervical spine extensor musculature, cervical sagittal balance, and clinical outcomes in cervical deformity (CD) patients. METHODS: Operative CD patients (C2-C7 Cobb > 10°, CL > ... Full text Open Access Link to item Cite

The clinical impact of global coronal malalignment is underestimated in adult patients with thoracolumbar scoliosis.

Journal Article Spine Deform · February 2020 STUDY DESIGN: Retrospective review of multicenter adult spine deformity (ASD) database. OBJECTIVES: A recent publication demonstrated that the laterality of the coronal offset is a key parameter that directly impacts postoperative outcomes. The objective o ... Full text Open Access Link to item Cite

Postoperative pyoderma gangrenosum after spinal fusion with instrumentation: case report.

Journal Article J Neurosurg Spine · February 1, 2020 Pyoderma gangrenosum (PG) is a rare inflammatory dermatosis that is most often associated with inflammatory bowel disease, but which can occur as a pathergic reaction around surgical incisions. The authors report the case of a patient who developed postope ... Full text Open Access Link to item Cite

Predicting the combined occurrence of poor clinical and radiographic outcomes following cervical deformity corrective surgery.

Journal Article J Neurosurg Spine · February 1, 2020 OBJECTIVE: Cervical deformity (CD) correction is clinically challenging. There is a high risk of developing complications with these highly complex procedures. The aim of this study was to use baseline demographic, clinical, and surgical factors to predict ... Full text Open Access Link to item Cite

Development of a Novel Cervical Deformity Surgical Invasiveness Index.

Journal Article Spine (Phila Pa 1976) · January 15, 2020 STUDY DESIGN: Retrospective review. OBJECTIVE: The aim of this study was to develop a novel surgical invasiveness index for cervical deformity (CD) surgery that incorporates CD-specific parameters. SUMMARY OF BACKGROUND DATA: There has been a surgical inva ... Full text Open Access Link to item Cite

Ventilator Mode Does Not Influence Blood Loss or Transfusion Requirements During Major Spine Surgery: A Retrospective Study.

Journal Article Anesth Analg · January 2020 BACKGROUND: Blood loss during adult spinal deformity surgery is multifactorial. Anesthetic-related factors, such as mode of mechanical ventilation, may contribute to intraoperative blood loss. The aim of this study was to determine the influence of ventila ... Full text Open Access Link to item Cite

Recurrent Proximal Junctional Kyphosis: Incidence, Risk Factors, Revision Rates, and Outcomes at 2-Year Minimum Follow-up.

Journal Article Spine (Phila Pa 1976) · January 1, 2020 STUDY DESIGN: Retrospective comparative cohort study. OBJECTIVE: Assess the incidence, risk factors, and outcomes of recurrent proximal junctional kyphosis (r-PJK) in PJK revision patients. SUMMARY OF BACKGROUND DATA: Several studies have identified the in ... Full text Open Access Link to item Cite

The Effect of Tobacco Smoking on Adverse Events Following Adult Complex Deformity Surgery: Analysis of 270 Patients From the Prospective, Multicenter Scoli-RISK-1 Study.

Journal Article Spine (Phila Pa 1976) · January 1, 2020 STUDY DESIGN: Post-hoc analysis of a prospective, multicenter cohort study. OBJECTIVE: To analyze the impact of smoking on rates of postoperative adverse events (AEs) in patients undergoing high-risk adult spine deformity surgery. SUMMARY OF BACKGROUND DAT ... Full text Open Access Link to item Cite

Incidence of Acute, Progressive, and Delayed Proximal Junctional Kyphosis Over an 8-Year Period in Adult Spinal Deformity Patients.

Journal Article Oper Neurosurg (Hagerstown) · January 1, 2020 BACKGROUND: Proximal junctional kyphosis (PJK) is a common radiographic complication of adult spinal deformity (ASD) corrective surgery. Although previous literature has reported a 5 to 61% incidence of PJK, these studies are limited by small sample sizes ... Full text Open Access Link to item Cite

Predicting the Occurrence of Postoperative Distal Junctional Kyphosis in Cervical Deformity Patients.

Journal Article Neurosurgery · January 1, 2020 BACKGROUND: Distal junctional kyphosis (DJK) development after cervical deformity (CD)-corrective surgery is a growing concern for surgeons and patients. Few studies have investigated risk factors that predict the occurrence of DJK. OBJECTIVE: To predict D ... Full text Open Access Link to item Cite

Obese Patients Benefit, but do not Fare as Well as Nonobese Patients, Following Lumbar Spondylolisthesis Surgery: An Analysis of the Quality Outcomes Database.

Journal Article Neurosurgery · January 1, 2020 BACKGROUND: Given recent differing findings following 2 randomized clinical trials on degenerative lumbar spondylolisthesis (DLS) surgery, there is a need to better define how subsets of patients fare following surgery. OBJECTIVE: To investigate the impact ... Full text Open Access Link to item Cite

Radiographic benefit of incorporating the inflection between the cervical and thoracic curves in fusion constructs for surgical cervical deformity patients.

Journal Article J Craniovertebr Junction Spine · 2020 PURPOSE: The aim is to assess the relationship between cervicothoracic inflection point and baseline disability, as well as the relationship between clinical outcomes and pre- to postoperative changes in inflection point. METHODS: Cervical deformity (CD) p ... Full text Open Access Link to item Cite

Patient satisfaction after minimally invasive spine surgery Response

Journal Article NEUROSURGICAL FOCUS · 2020 Full text Open Access Cite

Adult revision surgery of prior hook-and-rod wire instrumentation for idiopathic scoliosis.

Journal Article Neurosurg Focus Video · January 2020 Adolescent idiopathic scoliosis patients treated with spinal fusion may develop adjacent segment disease and curve progression into adulthood. Revision operations can be challenging, especially for adult patients treated with outdated instrumentation such ... Full text Open Access Link to item Cite

Revision thoracolumbar surgery for flat back deformity: staged ALIF and posterior column osteotomies to avoid three-column osteotomy.

Journal Article Neurosurg Focus Video · January 2020 Three-column osteotomies (3COs) can achieve significant alignment correction when revising fixed sagittal plane deformities; however, the technique is associated with high complication rates. The authors demonstrate staged anterior-posterior surgery with L ... Full text Open Access Link to item Cite

Back Injuries and Management of low Back Pain in Basketball

Chapter · January 1, 2020 Low back pain is common among the general population, with a prevalence of up to 80% [1]. However, professional athletes put repetitive, unnatural levels of stress on their spine in the form of dynamic loading (jumping), lateral bending, twisting, shear, a ... Full text Cite

Introduction: Video Illustrations of Techniques and Strategies for Adult and Pediatric Spinal Deformity Surgery

Journal Article Neurosurgical Focus: Video · January 1, 2020 Full text Open Access Cite

Less invasive spinal deformity surgery: the impact of the learning curve at tertiary spine care centers.

Journal Article J Neurosurg Spine · December 1, 2019 OBJECTIVE: The past decade has seen major advances in techniques for treating more complex spinal disorders using minimally invasive surgery (MIS). While appealing from the standpoint of patient perioperative outcomes, a major impediment to adoption has be ... Full text Open Access Link to item Cite

Impact of occupational characteristics on return to work for employed patients after elective lumbar spine surgery.

Journal Article Spine J · December 2019 BACKGROUND CONTEXT: Low back pain has an immense impact on the US economy. A significant number of patients undergo surgical management in order to regain meaningful functionality in daily life and in the workplace. Return to work (RTW) is a key metric in ... Full text Open Access Link to item Cite

Importance of Spinal Alignment in Primary and Metastatic Spine Tumors.

Journal Article World Neurosurg · December 2019 Spinal alignment, particularly with respect to spinopelvic parameters, is highly correlated with morbidity and health-related quality-of-life outcomes. Although the importance of spinal alignment has been emphasized in the deformity literature, spinopelvic ... Full text Open Access Link to item Cite

Younger Patients Are Differentially Affected by Stiffness-Related Disability Following Adult Spinal Deformity Surgery.

Journal Article World Neurosurg · December 2019 OBJECTIVE: The Lumbar Stiffness Disability Index (LSDI) assesses impact of lumbar stiffness on activities of daily living. We hypothesized that patients <60 years old would perceive greater lumbar stiffness-related functional limitation following fusion fo ... Full text Open Access Link to item Cite

Brief History of Spinal Neurosurgical Societies in the United States: Part 1.

Journal Article Neurospine · December 2019 Full text Open Access Link to item Cite

Association of Pneumonia, Wound Infection, and Sepsis with Clinical Outcomes after Acute Traumatic Spinal Cord Injury.

Journal Article J Neurotrauma · November 1, 2019 Pneumonia, wound infections, and sepsis (PWS) are the leading causes of acute mortality after traumatic spinal cord injury (SCI). However, the impact of PWS on neurological and functional outcomes is largely unknown. The present study analyzed participants ... Full text Open Access Link to item Cite

Predicting extended operative time and length of inpatient stay in cervical deformity corrective surgery.

Journal Article J Clin Neurosci · November 2019 It's increasingly common for surgeons to operate on more challenging cases and higher risk patients, resulting in longer op-time and inpatient LOS. Factors predicting extended op-time and LOS for cervical deformity (CD) patients are understudied. This stud ... Full text Open Access Link to item Cite

Cost-effectiveness of Operative versus Nonoperative Treatment of Adult Symptomatic Lumbar Scoliosis an Intent-to-treat Analysis at 5-year Follow-up.

Journal Article Spine (Phila Pa 1976) · November 1, 2019 STUDY DESIGN: Secondary analysis using data from the NIH-sponsored study on adult symptomatic lumbar scoliosis (ASLS) that included randomized and observational arms. OBJECTIVE: The aim of this study was to perform an intent-to-treat cost-effectiveness stu ... Full text Open Access Link to item Cite

Acute Adverse Events After Spinal Cord Injury and Their Relationship to Long-term Neurologic and Functional Outcomes: Analysis From the North American Clinical Trials Network for Spinal Cord Injury.

Journal Article Crit Care Med · November 2019 OBJECTIVES: There are few contemporary, prospective multicenter series on the spectrum of acute adverse events and their relationship to long-term outcomes after traumatic spinal cord injury. The goal of this study is to assess the prevalence of adverse ev ... Full text Open Access Link to item Cite

Relationship between body mass index and sagittal vertical axis change as well as health-related quality of life in 564 patients after deformity surgery.

Journal Article J Neurosurg Spine · November 1, 2019 OBJECTIVE: Obesity, a condition that is increasing in prevalence in the United States, has previously been associated with poorer outcomes following deformity surgery, including higher rates of perioperative complications such as deep and superficial infec ... Full text Open Access Link to item Cite

Surgical correction of severe adult lumbar scoliosis (major curves ≥ 75°): retrospective analysis with minimum 2-year follow-up.

Journal Article J Neurosurg Spine · October 1, 2019 OBJECTIVE: Prior reports have demonstrated the efficacy of surgical correction for adult lumbar scoliosis. Many of these reports focused on mild to moderate scoliosis. The authors' objective was to report their experience and to assess outcomes and complic ... Full text Open Access Link to item Cite

Development and validation of risk stratification models for adult spinal deformity surgery.

Journal Article J Neurosurg Spine · October 1, 2019 OBJECTIVE: Adult spinal deformity (ASD) surgery has a high rate of major complications (MCs). Public information about adverse outcomes is currently limited to registry average estimates. The object of this study was to assess the incidence of adverse even ... Full text Open Access Link to item Cite

Utility of neuromonitoring during lumbar pedicle subtraction osteotomy for adult spinal deformity.

Journal Article J Neurosurg Spine · September 1, 2019 OBJECTIVE: The benefits and utility of routine neuromonitoring with motor and somatosensory evoked potentials during lumbar spine surgery remain unclear. This study assesses measures of performance and utility of transcranial motor evoked potentials (MEPs) ... Full text Open Access Link to item Cite

Development of predictive models for all individual questions of SRS-22R after adult spinal deformity surgery: a step toward individualized medicine.

Journal Article Eur Spine J · September 2019 PURPOSE: Health-related quality of life (HRQL) instruments are essential in value-driven health care, but patients often have more specific, personal priorities when seeking surgical care. The Scoliosis Research Society-22R (SRS-22R), an HRQL instrument fo ... Full text Open Access Link to item Cite

Effect of Serious Adverse Events on Health-related Quality of Life Measures Following Surgery for Adult Symptomatic Lumbar Scoliosis.

Journal Article Spine (Phila Pa 1976) · September 1, 2019 STUDY DESIGN: Secondary analysis of prospective multicenter cohort. OBJECTIVE: To assess effect of serious adverse events (SAEs) on 2- and 4-year patient-reported outcomes measures (PROMs) in patients surgically treated for adult symptomatic lumbar scolios ... Full text Open Access Link to item Cite

Indicators for Nonroutine Discharge Following Cervical Deformity-Corrective Surgery: Radiographic, Surgical, and Patient-Related Factors.

Journal Article Neurosurgery · September 1, 2019 BACKGROUND: Nonroutine discharge, including discharge to inpatient rehab and skilled nursing facilities, is associated with increased cost-of-care. Given the rising prevalence of cervical deformity (CD)-corrective surgery and the necessity of value-based h ... Full text Open Access Link to item Cite

Development of Deployable Predictive Models for Minimal Clinically Important Difference Achievement Across the Commonly Used Health-related Quality of Life Instruments in Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · August 15, 2019 STUDY DESIGN: Retrospective analysis of prospectively-collected, multicenter adult spinal deformity (ASD) databases. OBJECTIVE: To predict the likelihood of reaching minimum clinically important differences in patient-reported outcomes after ASD surgery. S ... Full text Open Access Link to item Cite

Recovery kinetics following spinal deformity correction: a comparison of isolated cervical, thoracolumbar, and combined deformity morphometries.

Journal Article Spine J · August 2019 BACKGROUND CONTEXT: The postoperative recovery patterns of cervical deformity patients, thoracolumbar deformity patients, and patients with combined cervical and thoracolumbar deformities, all relative to one another, is not well understood. Clear objectiv ... Full text Open Access Link to item Cite

Effect of Prone Positional Apparatus on the Occurrence of Acute Kidney Injury After Spine Surgery.

Journal Article World Neurosurg · August 2019 BACKGROUND AND OBJECTIVE: Increased intra-abdominal pressure with prone positioning for spinal surgery is associated with intraoperative hemodynamic alterations and the potential for postoperative complications. This study investigated the incidence of pos ... Full text Open Access Link to item Cite

The Impact of Alvimopan on Return of Bowel Function After Major Spine Surgery - A Prospective, Randomized, Double-Blind Study.

Journal Article Neurosurgery · August 1, 2019 BACKGROUND: Pain management following major spine surgery requires high doses of opioids and is associated with a risk of opioid-induced constipation. Peripheral mu-receptor antagonists decrease the gastrointestinal complications of perioperative systemic ... Full text Open Access Link to item Cite

Grading of Complications After Cervical Deformity-corrective Surgery: Are Existing Classification Systems Applicable?

Journal Article Clin Spine Surg · July 2019 STUDY DESIGN: This is a retrospective review of prospective multicenter cervical deformity (CD) database. OBJECTIVE: Assess the impact of complication type and Clavien complication (Cc) grade on clinical outcomes of surgical CD patients BACKGROUND:: Valida ... Full text Open Access Link to item Cite

Minimally Invasive Surgery for Mild-to-Moderate Adult Spinal Deformities: Impact on Intensive Care Unit and Hospital Stay.

Journal Article World Neurosurg · July 2019 OBJECTIVE: To compare circumferential minimally invasive (cMIS) versus open surgeries for mild-to-moderate adult spinal deformity (ASD) with regard to intensive care unit (ICU) and hospital lengths of stay (LOS). METHODS: A retrospective review of 2 multic ... Full text Open Access Link to item Cite

Recovery Kinetics: Comparison of Patients Undergoing Primary or Revision Procedures for Adult Cervical Deformity Using a Novel Area Under the Curve Methodology.

Journal Article Neurosurgery · July 1, 2019 BACKGROUND: Limited data are available to objectively define what constitutes a "good" versus a "bad" recovery for operative cervical deformity (CD) patients. Furthermore, the recovery patterns of primary versus revision procedures for CD is poorly underst ... Full text Open Access Link to item Cite

Artificial Intelligence Based Hierarchical Clustering of Patient Types and Intervention Categories in Adult Spinal Deformity Surgery: Towards a New Classification Scheme that Predicts Quality and Value.

Journal Article Spine (Phila Pa 1976) · July 1, 2019 STUDY DESIGN: Retrospective review of prospectively-collected, multicenter adult spinal deformity (ASD) databases. OBJECTIVE: To apply artificial intelligence (AI)-based hierarchical clustering as a step toward a classification scheme that optimizes overal ... Full text Open Access Link to item Cite

The Safety And Efficacy Of Riluzole As A Neuroprotective Therapy In Patients Undergoing Surgical Decompression For Cervical Spondylotic Myelopathy: Results Of The CSM-Protect Trial

Conference JOURNAL OF NEUROSURGERY · July 1, 2019 Link to item Cite

A Predictive Model and Nomogram for Predicting Return to Work at 3 Months After Cervical Spine Surgery: An Analysis from the Quality Outcome Database

Conference JOURNAL OF NEUROSURGERY · July 1, 2019 Link to item Cite

The Impact of Osteotomy Grade and Location on Regional and Global Alignment Following Cervical Deformity Surgery

Conference JOURNAL OF NEUROSURGERY · July 1, 2019 Link to item Cite

Pseudarthrosis in adult and pediatric spinal deformity surgery: a systematic review of the literature and meta-analysis of incidence, characteristics, and risk factors.

Journal Article Neurosurg Rev · June 2019 We conducted a systematic review with meta-analysis and qualitative synthesis. This study aims to characterize pseudarthrosis after long-segment fusion in spinal deformity by identifying incidence rates by etiology, risk factors for its development, and co ... Full text Open Access Link to item Cite

Effect of Modified Japanese Orthopedic Association Severity Classifications on Satisfaction With Outcomes 12 Months After Elective Surgery for Cervical Spine Myelopathy.

Journal Article Spine (Phila Pa 1976) · June 1, 2019 STUDY DESIGN: This study retrospectively analyzes prospectively collected data. OBJECTIVE: Here, we aim to determine the influence of preoperative and 12-month modified Japanese Orthopedic Association (mJOA) on satisfaction and understand the change in mJO ... Full text Open Access Link to item Cite

Examining the Patient-Reported Outcomes Measurement Information System versus the Scoliosis Research Society-22r in adult spinal deformity.

Journal Article J Neurosurg Spine · June 1, 2019 OBJECTIVE: After using PROsetta Stone crosswalk tables to calculate Patient-Reported Outcomes Measurement Information System (PROMIS) Physical Function (PF) and Pain Interference (PI) scores, the authors sought to examine 1) correlations with Scoliosis Res ... Full text Open Access Link to item Cite

What Factors Predict the Risk of Proximal Junctional Failure in the Long Term, Demographic, Surgical, or Radiographic?: Results From a Time-dependent ROC Curve.

Journal Article Spine (Phila Pa 1976) · June 1, 2019 STUDY DESIGN: Retrospective review of prospective multicenter database. OBJECTIVE: To identify an optimal set of factors predicting the risk of proximal junctional failure (PJF) while taking the time dependency of PJF and those factors into account. SUMMAR ... Full text Open Access Link to item Cite

Limited morbidity and possible radiographic benefit of C2 vs. subaxial cervical upper-most instrumented vertebrae.

Journal Article J Spine Surg · June 2019 BACKGROUND: The study aims to evaluate differences in alignment and clinical outcomes between surgical cervical deformity (CD) patients with a subaxial upper-most instrumented vertebra (UIV) and patients with a UIV at C2. Use of CD-corrective instrumentati ... Full text Open Access Link to item Cite

Effect of Obesity on Radiographic Alignment and Short-Term Complications After Surgical Treatment of Adult Cervical Deformity.

Journal Article World Neurosurg · May 2019 OBJECTIVE: We investigated the 30-day complication incidence and 1-year radiographic correction in obese patients undergoing surgical treatment of cervical deformity. METHODS: The patients were stratified according to World Health Organization's definition ... Full text Open Access Link to item Cite

Treatment of adult thoracolumbar spinal deformity: past, present, and future.

Journal Article J Neurosurg Spine · May 1, 2019 Care of the patient with adult spinal deformity (ASD) has evolved from being primarily supportive to now having the ability to directly treat and correct the spinal pathology. The focus of this narrative literature review is to briefly summarize the histor ... Full text Open Access Link to item Cite

Predictive model for long-term patient satisfaction after surgery for grade I degenerative lumbar spondylolisthesis: insights from the Quality Outcomes Database.

Journal Article Neurosurg Focus · May 1, 2019 OBJECTIVESince the enactment of the Affordable Care Act in 2010, providers and hospitals have increasingly prioritized patient-centered outcomes such as patient satisfaction in an effort to adapt the "value"-based healthcare model. In the current study, th ... Full text Open Access Link to item Cite

A comparison of minimally invasive transforaminal lumbar interbody fusion and decompression alone for degenerative lumbar spondylolisthesis.

Journal Article Neurosurg Focus · May 1, 2019 OBJECTIVEThe optimal minimally invasive surgery (MIS) approach for grade 1 lumbar spondylolisthesis is not clearly elucidated. In this study, the authors compared the 24-month patient-reported outcomes (PROs) after MIS transforaminal lumbar interbody fusio ... Full text Open Access Link to item Cite

Optimal tether configurations and preload tensioning to prevent proximal junctional kyphosis: a finite element analysis.

Journal Article J Neurosurg Spine · May 1, 2019 OBJECTIVE: Proximal junctional kyphosis (PJK) is, in part, due to altered segmental biomechanics at the junction of rigid instrumented spine and relatively hypermobile non-instrumented adjacent segments. Proper application of posteriorly anchored polyethyl ... Full text Open Access Link to item Cite

Low rates of complications after spinopelvic fixation with iliac screws in 260 adult patients with a minimum 2-year follow-up.

Journal Article J Neurosurg Spine · May 1, 2019 OBJECTIVE: Recent literature describing complications associated with spinopelvic fixation with iliac screws in adult patients has been limited but has suggested high complication rates. The authors' objective was to report their experience with iliac scre ... Full text Open Access Link to item Cite

Evolution and Advancement of Adult Spinal Deformity Research and Clinical Care: An Overview of the Scoli-RISK-1 Study

Journal Article Global Spine Journal · May 1, 2019 Study Design: Narrative review. Objective: The prevalence of adult spinal deformity (ASD) has been cited anywhere between 2-32%, while the prevalence in the elderly population has been estimated at 68%. Neurologic complications following ASD surgery remain ... Full text Open Access Cite

Responding to Intraoperative Neuromonitoring Changes During Pediatric Coronal Spinal Deformity Surgery

Journal Article Global Spine Journal · May 1, 2019 Study Design: Retrospective case study on prospectively collected data. Objectives: The purpose of this explorative study was: 1) to determine if patterns of spinal cord injury could be detected through intra-operative neuromonitoring (IONM) changes in ped ... Full text Open Access Cite

Comparison of Best Versus Worst Clinical Outcomes for Adult Cervical Deformity Surgery.

Journal Article Global Spine J · May 2019 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: Factors that predict outcomes for adult cervical spine deformity (ACSD) have not been well defined. To compare ACSD patients with best versus worst outcomes. METHODS: This study was based on a prospectiv ... Full text Open Access Link to item Cite

Evolution in Surgical Approach, Complications, and Outcomes in an Adult Spinal Deformity Surgery Multicenter Study Group Patient Population.

Journal Article Spine Deform · May 2019 STUDY DESIGN: Retrospective review of a prospectively collected multicenter database. OBJECTIVES: To evaluate the evolution of surgical treatment strategies, complications, and patient-reported outcomes for adult spinal deformity (ASD) patients. ASD surger ... Full text Open Access Link to item Cite

Comparison of Outcomes Following Anterior vs Posterior Fusion Surgery for Patients With Degenerative Cervical Myelopathy: An Analysis From Quality Outcomes Database.

Journal Article Neurosurgery · April 1, 2019 BACKGROUND: The choice of anterior vs posterior approach for degenerative cervical myelopathy that spans multiple segments remains controversial. OBJECTIVE: To compare the outcomes following the 2 approaches using multicenter prospectively collected data. ... Full text Open Access Link to item Cite

Rotational thromboelastometry-guided transfusion during lumbar pedicle subtraction osteotomy for adult spinal deformity: preliminary findings from a matched cohort study.

Journal Article Neurosurg Focus · April 1, 2019 OBJECTIVESignificant blood loss and coagulopathy are often encountered during adult spinal deformity (ASD) surgery, and the optimal intraoperative transfusion algorithm is debatable. Rotational thromboelastometry (ROTEM), a functional viscoelastometric met ... Full text Open Access Link to item Cite

Utility of topical tranexamic acid for adult patients with spinal deformity and contraindications to systemic tranexamic acid: initial experience and report of 2 cases.

Journal Article J Neurosurg Spine · April 1, 2019 Tranexamic acid (TXA) is an antifibrinolytic agent with demonstrated efficacy in reducing blood loss when administered systemically. However, in patients with contraindications to systemic or intravenous TXA, topical TXA (tTXA) has been shown to reduce per ... Full text Open Access Link to item Cite

Unilateral versus bilateral lower extremity motor deficit following complex adult spinal deformity surgery: is there a difference in recovery up to 2-year follow-up?

Journal Article Spine J · March 2019 BACKGROUND CONTEXT: Scoli-RISK-1 is a multicenter prospective cohort designed to study neurologic outcomes following complex adult spinal deformity (ASD). The effect of unilateral versus bilateral postoperative motor deficits on the likelihood of long-term ... Full text Open Access Link to item Cite

Operative Versus Nonoperative Treatment for Adult Symptomatic Lumbar Scoliosis.

Journal Article J Bone Joint Surg Am · February 20, 2019 BACKGROUND: The effectiveness of operative compared with nonoperative treatment at initial presentation (no prior fusion) for adult lumbar scoliosis has not, to our knowledge, been evaluated in controlled trials. The goals of this study were to evaluate th ... Full text Open Access Link to item Cite

Characteristics of deformity surgery in patients with severe and rigid cervical kyphosis (CK): results of the CSRS-Europe multi-centre study project.

Journal Article Eur Spine J · February 2019 INTRODUCTION AND PURPOSE: Little information exists on surgical characteristics, complications and outcomes with corrective surgery for rigid cervical kyphosis (CK). To collate the experience of international experts, the CSRS-Europe initiated an internati ... Full text Open Access Link to item Cite

Effect of Resident and Fellow Involvement in Adult Spinal Deformity Surgery.

Journal Article World Neurosurg · February 2019 BACKGROUND: Adult spinal deformity (ASD) operations are complex and often require a multisurgeon team. Simultaneously, it is the responsibility of academic spine surgeons to train future complex spine surgeons. Our objective was to assess the effect of res ... Full text Open Access Link to item Cite

Development of a Modified Cervical Deformity Frailty Index: A Streamlined Clinical Tool for Preoperative Risk Stratification.

Journal Article Spine (Phila Pa 1976) · February 1, 2019 STUDY DESIGN: Retrospective review. OBJECTIVE: Develop a simplified frailty index for cervical deformity (CD) patients. SUMMARY OF BACKGROUND DATA: To improve preoperative risk stratification for surgical CD patients, a CD frailty index (CD-FI) incorporati ... Full text Open Access Link to item Cite

Extended Asymmetrical Pedicle Subtraction Osteotomy for Adult Spinal Deformity: 2-Dimensional Operative Video.

Journal Article Oper Neurosurg (Hagerstown) · February 1, 2019 Pedicle subtraction osteotomy (PSO) is an effective technique to correct fixed sagittal malalignment. A variation of this technique, the "trans-discal" or "extended" PSO (Schwab grade IV osteotomy), involves extending the posterior wedge resection of the i ... Full text Open Access Link to item Cite

A Pilot Study on Posterior Polyethylene Tethers to Prevent Proximal Junctional Kyphosis After Multilevel Spinal Instrumentation for Adult Spinal Deformity.

Journal Article Oper Neurosurg (Hagerstown) · February 1, 2019 BACKGROUND: Proximal junctional kyphosis (PJK) is a common problem after multilevel spine instrumentation. OBJECTIVE: To determine if junctional tethers reduce PJK after multilevel instrumented surgery for adult spinal deformity (ASD). METHODS: ASD patient ... Full text Open Access Link to item Cite

A Novel Junctional Tether Weave Technique for Adult Spinal Deformity: 2-Dimensional Operative Video.

Journal Article Oper Neurosurg (Hagerstown) · February 1, 2019 Proximal junctional kyphosis (PJK) is a common problem after multilevel spine instrumentation for adult spinal deformity. Various anti-PJK techniques such as junctional tethers for ligamentous augmentation have been proposed. We present an operative video ... Full text Open Access Link to item Cite

Laminectomy alone versus fusion for grade 1 lumbar spondylolisthesis in 426 patients from the prospective Quality Outcomes Database.

Journal Article J Neurosurg Spine · February 1, 2019 OBJECTIVEThe AANS launched the Quality Outcomes Database (QOD), a prospective longitudinal registry that includes demographic, clinical, and patient-reported outcome (PRO) data to measure the safety and quality of spine surgery. Registry data offer "real-w ... Full text Open Access Link to item Cite

Radiographic outcome and complications after single-level lumbar extended pedicle subtraction osteotomy for fixed sagittal malalignment: a retrospective analysis of 55 adult spinal deformity patients with a minimum 2-year follow-up.

Journal Article J Neurosurg Spine · February 1, 2019 OBJECTIVEFixed sagittal spinal malalignment is a common problem in adult spinal deformity (ASD). Various three-column osteotomy techniques, including the extended pedicle subtraction osteotomy (ePSO), may correct global and regional malalignment in this pa ... Full text Open Access Link to item Cite

Non-neurologic adverse events after complex adult spinal deformity surgery: results from the prospective, multicenter Scoli-RISK-1 study.

Journal Article Eur Spine J · January 2019 PURPOSE: Accurate information regarding the expected complications of complex adult spinal deformity (ASD) is important for shared decision making and informed consent. The purpose of the present study was to investigate the rate and types of non-neurologi ... Full text Open Access Link to item Cite

Alignment Risk Factors for Proximal Junctional Kyphosis and the Effect of Lower Thoracic Junctional Tethers for Adult Spinal Deformity.

Journal Article World Neurosurg · January 2019 OBJECTIVE: The aims of this retrospective cohort study were to 1) identify new alignment risk factors for proximal junctional kyphosis (PJK) in adult spinal deformity (ASD) patients with lower thoracic upper instrumented vertebra (UIV) and 2) determine the ... Full text Open Access Link to item Cite

Surgery for the Adolescent Idiopathic Scoliosis Patients After Skeletal Maturity: Early Versus Late Surgery.

Journal Article Spine Deform · January 2019 INTRODUCTION: Informed decision making for operative treatment of the skeletally mature adolescent idiopathic scoliosis (AIS) patient meeting surgical indications requires a discussion of differences in operative morbidity in adult scoliosis versus AIS. Th ... Full text Open Access Link to item Cite

Determinants of Patient Satisfaction 2 Years After Spinal Deformity Surgery: A Latent Class Analysis.

Journal Article Spine (Phila Pa 1976) · January 1, 2019 STUDY DESIGN: Retrospective review of prospective multicenter database. OBJECTIVE: To investigate the determinants of patient satisfaction with respect to changes in functional limitations 2 years after spinal deformity surgery. SUMMARY OF BACKGROUND DATA: ... Full text Open Access Link to item Cite

Location of correction within the lumbar spine impacts acute adjacent-segment kyphosis.

Journal Article J Neurosurg Spine · January 1, 2019 OBJECTIVEThe surgical correction of adult spinal deformity (ASD) often involves modifying lumbar lordosis (LL) to restore ideal sagittal alignment. However, corrections that include large changes in LL increase the risk for development of proximal junction ... Full text Open Access Link to item Cite

Cervical mismatch: the normative value of T1 slope minus cervical lordosis and its ability to predict ideal cervical lordosis.

Journal Article J Neurosurg Spine · January 1, 2019 OBJECTIVE: Numerous studies have attempted to delineate the normative value for T1S-CL (T1 slope minus cervical lordosis) as a marker for both cervical deformity and a goal for correction similar to how PI-LL (pelvic incidence-lumbar lordosis) mismatch inf ... Full text Open Access Link to item Cite

The Clinical Impact of Global Coronal Malalignment Is Underestimated in Adult Patients With Thoracolumbar Scoliosis

Journal Article Spine Deformity · January 1, 2019 Study Design: Retrospective review of multicenter adult spine deformity (ASD) database. Objectives: A recent publication demonstrated that the laterality of the coronal offset is a key parameter that directly impacts postoperative outcomes. The objective o ... Full text Open Access Cite

The impact of osteotomy grade and location on regional and global alignment following cervical deformity surgery.

Journal Article J Craniovertebr Junction Spine · 2019 INTRODUCTION: Correction of cervical deformity (CD) often involves different types of osteotomies to address sagittal malalignment. This study assessed the relationship between osteotomy grade and vertebral level on alignment and clinical outcomes. METHODS ... Full text Open Access Link to item Cite

Global spinal deformity from the upper cervical perspective. What is "Abnormal" in the upper cervical spine?

Journal Article J Craniovertebr Junction Spine · 2019 HYPOTHESIS: Reciprocal changes in the upper cervical spine correlate with adult TL deformity modifiers. DESIGN: This was a retrospective review. INTRODUCTION: The upper cervical spine has remarkable adaptability to wide ranges of thoracolumbar (TL) deformi ... Full text Open Access Link to item Cite

Neuroanesthesia Guidelines for Optimizing Transcranial Motor Evoked Potentials Neuromonitoring During Deformity and Complex Spinal Surgery: A Delphi Consensus Study

Conference NEUROSURGERY · 2019 Cite

Atlantoaxial stabilization

Chapter · December 22, 2018 Full text Cite

Predictive model for distal junctional kyphosis after cervical deformity surgery.

Journal Article Spine J · December 2018 BACKGROUND CONTEXT: Distal junctional kyphosis (DJK) is a primary concern of surgeons correcting cervical deformity. Identifying patients and procedures at higher risk of developing this condition is paramount in improving patient selection and care. PURPO ... Full text Open Access Link to item Cite

Diversity in Surgical Decision Strategies for Adult Spine Deformity Treatment: The Effects of Neurosurgery or Orthopedic Training Background and Surgical Experience.

Journal Article Neurospine · December 2018 OBJECTIVE: This study is aimed to investigate whether surgical strategies for adult spinal deformity (ASD) treatment differed among Korean physicians. METHODS: This study is retrospective questionnaire-based study. ASD is challenging to manage, with a broa ... Full text Open Access Link to item Cite

Cervical Versus Thoracolumbar Spinal Deformities: A Comparison of Baseline Quality-of-Life Burden.

Journal Article Clin Spine Surg · December 2018 STUDY DESIGN: Retrospective analysis of 2 prospectively collected multicenter databases, one for cervical deformity (CD) and the other for general adult spinal deformity. OBJECTIVE: To investigate the relative quality-of-life and disability burden in patie ... Full text Open Access Link to item Cite

Prospective Multicenter Assessment of All-Cause Mortality Following Surgery for Adult Cervical Deformity.

Journal Article Neurosurgery · December 1, 2018 BACKGROUND: Surgical treatments for adult cervical spinal deformity (ACSD) are often complex and have high complication rates. OBJECTIVE: To assess all-cause mortality following ACSD surgery. METHODS: ACSD patients presenting for surgical treatment were id ... Full text Open Access Link to item Cite

Presentation and Outcomes After Medical and Surgical Treatment Versus Medical Treatment Alone of Spontaneous Infectious Spondylodiscitis: A Systematic Literature Review and Meta-Analysis

Journal Article Global Spine Journal · December 1, 2018 Study Design: Systematic literature review. Objectives: The aims of this study were to (1) describe the clinical features, disabilities, and incidence of neurologic deficits of pyogenic spondylodiscitis prior to treatment and (2) compare the functional out ... Full text Open Access Cite

Identifying Thoracic Compensation and Predicting Reciprocal Thoracic Kyphosis and Proximal Junctional Kyphosis in Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · November 1, 2018 STUDY DESIGN: Retrospective analysis. OBJECTIVE: To define thoracic compensation and investigate its association with postoperative reciprocal thoracic kyphosis and proximal junctional kyphosis (PJK) SUMMARY OF BACKGROUND DATA.: Adult spinal deformity (ASD ... Full text Open Access Link to item Cite

Incidence and Predictive Factors of Sepsis Following Adult Spinal Deformity Surgery.

Journal Article Neurosurgery · November 1, 2018 BACKGROUND: Surgery for adult spinal deformity (ASD) improves quality of life, yet morbidity is high. Sepsis is a challenging postoperative complication that can result in death and drive inpatient resources. OBJECTIVE: To identify the incidence and risk f ... Full text Open Access Link to item Cite

Natural History, Predictors of Outcome, and Effects of Treatment in Thoracic Spinal Cord Injury: A Multi-Center Cohort Study from the North American Clinical Trials Network.

Journal Article J Neurotrauma · November 1, 2018 The course, treatment response, and recovery potential after acute traumatic spinal cord injury (SCI) have been shown to differ depending on the neurological level of injury. There are limited data focused on thoracic-level injuries, however. A cohort of 8 ... Full text Open Access Link to item Cite

Outcomes of Operative Treatment for Adult Cervical Deformity: A Prospective Multicenter Assessment With 1-Year Follow-up.

Journal Article Neurosurgery · November 1, 2018 BACKGROUND: Despite the potential for profound impact of adult cervical deformity (ACD) on function and health-related quality of life (HRQOL), there are few high-quality studies that assess outcomes of surgical treatment for these patients. OBJECTIVE: To ... Full text Open Access Link to item Cite

Development of a validated computer-based preoperative predictive model for pseudarthrosis with 91% accuracy in 336 adult spinal deformity patients.

Journal Article Neurosurg Focus · November 1, 2018 OBJECTIVEPseudarthrosis can occur following adult spinal deformity (ASD) surgery and can lead to instrumentation failure, recurrent pain, and ultimately revision surgery. In addition, it is one of the most expensive complications of ASD surgery. Risk facto ... Full text Open Access Link to item Cite

A predictive model and nomogram for predicting return to work at 3 months after cervical spine surgery: an analysis from the Quality Outcomes Database.

Journal Article Neurosurg Focus · November 1, 2018 OBJECTIVEBack pain and neck pain are two of the most common causes of work loss due to disability, which poses an economic burden on society. Due to recent changes in healthcare policies, patient-centered outcomes including return to work have been increas ... Full text Open Access Link to item Cite

The impact of age on surgical goals for spinopelvic alignment in minimally invasive surgery for adult spinal deformity.

Journal Article J Neurosurg Spine · November 1, 2018 OBJECTIVEAchieving appropriate spinopelvic alignment in deformity surgery has been correlated with improvement in pain and disability. Minimally invasive surgery (MIS) techniques have been used to treat adult spinal deformity (ASD); however, there is conce ... Full text Open Access Link to item Cite

Letter to the Editor. Proximal junctional kyphosis and proximal junctional failure.

Journal Article J Neurosurg Spine · November 1, 2018 Full text Open Access Link to item Cite

External Validation of the Adult Spinal Deformity (ASD) Frailty Index (ASD-FI) in the Scoli-RISK-1 Patient Database.

Journal Article Spine (Phila Pa 1976) · October 15, 2018 STUDY DESIGN: Analysis of a prospective multicenter database. OBJECTIVE: To assess the ability of the recently created Adult Spinal Deformity (ASD) Frailty Index (ASD-FI) to predict odds of major complications and length of hospital stay for patients who h ... Full text Open Access Link to item Cite

Clinical and radiographic presentation and treatment of patients with cervical deformity secondary to thoracolumbar proximal junctional kyphosis are distinct despite achieving similar outcomes: Analysis of 123 prospective CD cases.

Journal Article J Clin Neurosci · October 2018 CD development secondary to PJK was recently documented in adult spinal deformity patients after surgical correction for thoracolumbar ASD. This study analyzes surgical management of patients with CD secondary to proximal junctional kyphosis (PJK) versus p ... Full text Open Access Link to item Cite

Incidence and risk factors of postoperative neurologic decline after complex adult spinal deformity surgery: results of the Scoli-RISK-1 study.

Journal Article Spine J · October 2018 BACKGROUND CONTEXT: Significant variability in neurologic outcomes after surgical correction for adult spinal deformity (ASD) has been reported. Risk factors for decline in neurologic motor outcomes are poorly understood. PURPOSE: The objective of the pres ... Full text Open Access Link to item Cite

Primary Drivers of Adult Cervical Deformity: Prevalence, Variations in Presentation, and Effect of Surgical Treatment Strategies on Early Postoperative Alignment.

Journal Article Neurosurgery · October 1, 2018 BACKGROUND: Primary drivers (PDs) of adult cervical deformity (ACD) have not been described in relation to pre- and early postoperative alignment or degree of correction. OBJECTIVE: To define the PDs of ACD to understand the impact of driver region on glob ... Full text Open Access Link to item Cite

Rod Fracture After Apparently Solid Radiographic Fusion in Adult Spinal Deformity Patients.

Journal Article World Neurosurg · September 2018 BACKGROUND: Rod fracture occurs with delayed fusion or pseudarthrosis after adult spinal deformity (ASD) surgery. Rod fracture after apparent radiographic fusion has not been previously investigated. METHODS: Patients with ASD in a multicenter database wer ... Full text Open Access Link to item Cite

Radiographic Fusion Grade Does Not Impact Health-Related Quality of Life in the Absence of Instrumentation Failure for Patients Undergoing Posterior Instrumented Fusion for Adult Spinal Deformity.

Journal Article World Neurosurg · September 2018 BACKGROUND: Pseudarthrosis and rod fracture (RF) remain significant concerns after fusion for adult spinal deformity (ASD). Although a radiographic system of fusion grade has been proposed, the correlation between fusion grade and health-related quality of ... Full text Open Access Link to item Cite

Cost-utility analysis of cervical deformity surgeries using 1-year outcome.

Journal Article Spine J · September 2018 BACKGROUND CONTEXT: Cost-utility analysis, a special case of cost-effectiveness analysis, estimates the ratio between the cost of an intervention to the benefit it produces in number of quality-adjusted life years. Cervical deformity correction has not bee ... Full text Open Access Link to item Cite

External validation of the adult spinal deformity (ASD) frailty index (ASD-FI).

Journal Article Eur Spine J · September 2018 PURPOSE: To assess the ability of the recently developed adult spinal deformity frailty index (ASD-FI) to predict odds of perioperative complications, odds of reoperation, and length of hospital stay after adult spinal deformity (ASD) surgery using a datab ... Full text Open Access Link to item Cite

Patients with Adult Spinal Deformity with Previous Fusions Have an Equal Chance of Reaching Substantial Clinical Benefit Thresholds in Health-Related Quality of Life Measures but Do Not Reach the Same Absolute Level of Improvement.

Journal Article World Neurosurg · August 2018 BACKGROUND: Substantial clinical benefit (SCB) represents a threshold above which patients recognize substantial improvement and represents a rational target for defining clinical success. In adult spinal deformity (ASD) surgery, previous fusions may impac ... Full text Open Access Link to item Cite

THE EFFECT OF RILUZOLE ON INTRAMEDULLARY LESION LENGTH AND DTI, RATIONALE AND DESIGN OF RISCIS MRI-SUBSTUDY

Conference JOURNAL OF NEUROTRAUMA · August 1, 2018 Open Access Link to item Cite

The Relationship Between Improvements in Myelopathy and Sagittal Realignment in Cervical Deformity Surgery Outcomes.

Journal Article Spine (Phila Pa 1976) · August 2018 STUDY DESIGN: Retrospective review. OBJECTIVE: Determine whether alignment or myelopathy improvement drives patient outcomes after cervical deformity (CD) corrective surgery. SUMMARY OF BACKGROUND DATA: CD correction involves radiographic malalignment corr ... Full text Open Access Link to item Cite

After 9 Years of 3-Column Osteotomies, Are We Doing Better? Performance Curve Analysis of 573 Surgeries With 2-Year Follow-up.

Journal Article Neurosurgery · July 1, 2018 BACKGROUND: In spinal deformity treatment, the increased utilization of 3-column (3CO) osteotomies reflects greater comfort and better training among surgeons. This study aims to evaluate the longitudinal performance and adverse events (complications or re ... Full text Open Access Link to item Cite

In Reply: Incidence and Predictive Factors of Sepsis Following Adult Spinal Deformity Surgery.

Journal Article Neurosurgery · July 1, 2018 Full text Open Access Link to item Cite

Analysis of Successful Versus Failed Radiographic Outcomes After Cervical Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · July 1, 2018 STUDY DESIGN: Prospective multicenter cohort study with consecutive enrollment. OBJECTIVE: To evaluate preoperative alignment and surgical factors associated with suboptimal early postoperative radiographic outcomes after surgery for cervical deformity. SU ... Full text Open Access Link to item Cite

Minimum Detectable Measurement Difference for Health-Related Quality of Life Measures Varies With Age and Disability in Adult Spinal Deformity: Implications for Calculating Minimal Clinically Important Difference.

Journal Article Spine (Phila Pa 1976) · July 1, 2018 STUDY DESIGN: Retrospective cohort. OBJECTIVE: To investigate the minimum detectable measurement difference (MDMD) in the Scoliosis Research Society-22r (SRS-22r) outcomes instrument in adult spinal deformity (ASD) and to evaluate the effect of baseline da ... Full text Open Access Link to item Cite

An Analysis of the Incidence and Outcomes of Major Versus Minor Neurological Decline After Complex Adult Spinal Deformity Surgery: A Subanalysis of Scoli-RISK-1 Study.

Journal Article Spine (Phila Pa 1976) · July 1, 2018 STUDY DESIGN: A subanalysis from a prospective, multicenter, international cohort study in 15 sites (Scoli-RISK-1). OBJECTIVE: To report detailed information regarding the severity of neurological decline related to complex adult spine deformity (ASD) surg ... Full text Open Access Link to item Cite

Approach Selection: Multiple Anterior Lumbar Interbody Fusion to Recreate Lumbar Lordosis Versus Pedicle Subtraction Osteotomy: When, Why, How?

Journal Article Neurosurg Clin N Am · July 2018 Restoration of physiologic lumbar lordosis is a fundamental principle of spinal deformity surgery. Techniques using multilevel anterior lumbar interbody fusion or pedicle subtraction osteotomy (PSO) are described. Multilevel anterior lumbar interbody fusio ... Full text Open Access Link to item Cite

Peak Timing for Complications After Adult Spinal Deformity Surgery.

Journal Article World Neurosurg · July 2018 BACKGROUND: Overall complication rates for adult spinal deformity (ASD) surgery have been reported; however, little data exist on the peak timing associated with specific complications. This study quantifies the peak timing for multiple complication types ... Full text Open Access Link to item Cite

Predictive Modeling of Length of Hospital Stay Following Adult Spinal Deformity Correction: Analysis of 653 Patients with an Accuracy of 75% within 2 Days.

Journal Article World Neurosurg · July 2018 BACKGROUND: Length of stay (LOS) after surgery for adult spinal deformity (ASD) is a critical period that allows for optimal recovery. Predictive models that estimate LOS allow for stratification of high-risk patients. METHODS: A prospectively acquired mul ... Full text Open Access Link to item Cite

T1 Slope Minus Cervical Lordosis (TS-CL), the Cervical Answer to PI-LL, Defines Cervical Sagittal Deformity in Patients Undergoing Thoracolumbar Osteotomy.

Journal Article Int J Spine Surg · June 2018 BACKGROUND: Cervical kyphosis and C2-C7 plumb line (CPL) are established descriptors of cervical sagittal deformity (CSD). Reciprocal changes in these parameters have been demonstrated in thoracolumbar deformity correction. The purpose of this study was to ... Full text Open Access Link to item Cite

Frequency and Acceptability of Adverse Events After Anterior Cervical Discectomy and Fusion: A Survey Study From the Cervical Spine Research Society.

Journal Article Clin Spine Surg · June 2018 PURPOSE: Anterior cervical discectomy and fusion has a low but well-established profile of adverse events. The goal of this study was to gauge surgeon opinion regarding the frequency and acceptability of these events. METHODS: A 2-page survey was distribut ... Full text Open Access Link to item Cite

Ethnic Variations in Radiographic Parameters and SRS-22 Scores in Adult Spinal Deformity: A Comparison Between North American and Japanese Patients Above 50 Years of Age With Minimum 2-Year Follow-up.

Journal Article Clin Spine Surg · June 2018 STUDY DESIGN: Retrospective review of North American and Japanese adult spinal deformity (ASD) database. OBJECTIVE: To investigate the ethnical differences in radiographic parameters and Scoliosis Research Society (SRS)-22 between North American and Japane ... Full text Open Access Link to item Cite

Serious Adverse Events Significantly Reduce Patient-Reported Outcomes at 2-Year Follow-up: Nonoperative, Multicenter, Prospective NIH Study of 105 Patients.

Journal Article Spine (Phila Pa 1976) · June 1, 2018 STUDY DESIGN: This is an analysis of a prospective 2-year study on nonoperative patients enrolled in the Adult Symptomatic Lumbar Scoliosis (ASLS) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) trial. OBJECTIVE: The purpose w ... Full text Open Access Link to item Cite

The Prevalence of Incidental and Symptomatic Lumbar Synovial Facet Cysts

Journal Article Clinical Spine Surgery: A Spine Publication · June 2018 Study Design:This was a retrospective cohort study from 2 affiliated tertiary care referral centers for spine disease. Full text Open Access Cite

The Lumbar Pelvic Angle, the Lumbar Component of the T1 Pelvic Angle, Correlates With HRQOL, PI-LL Mismatch, and it Predicts Global Alignment.

Journal Article Spine (Phila Pa 1976) · May 15, 2018 STUDY DESIGN: Prospective multicenter analysis of adult spinal deformity (ASD) patients. OBJECTIVE: The aim of this study was to introduce the lumbar pelvic angle (LPA), a novel parameter of spinopelvic alignment. SUMMARY OF BACKGROUND DATA: The T1 pelvic ... Full text Open Access Link to item Cite

Clinically Significant Thromboembolic Disease in Adult Spinal Deformity Surgery: Incidence and Risk Factors in 737 Patients

Journal Article Global Spine Journal · May 1, 2018 Study Design: Retrospective cohort study. Objectives: Describe the rate and risk factors for venous thromboembolic events (VTEs; defined as deep venous thrombosis [DVT] and/or pulmonary embolism [PE]) in adult spinal deformity (ASD) surgery. Methods: ASD p ... Full text Open Access Cite

Lower Extremity Motor Function Following Complex Adult Spinal Deformity Surgery: Two-Year Follow-up in the Scoli-RISK-1 Prospective, Multicenter, International Study.

Journal Article J Bone Joint Surg Am · April 18, 2018 BACKGROUND: The reported neurologic complication rate following surgery for complex adult spinal deformity (ASD) is variable due to several factors. Most series have been retrospective with heterogeneous patient populations and use of nonuniform neurologic ... Full text Open Access Link to item Cite

Inter- and Intra-rater Reliability of the Hart-ISSG Proximal Junctional Failure Severity Scale.

Journal Article Spine (Phila Pa 1976) · April 15, 2018 STUDY DESIGN: Reliability/external validation study. OBJECTIVE: Investigate inter- and intrarater reliability of the Hart-International Spine Study Group (ISSG) Proximal Junctional Failure Severity Scale (PJFSS) and its correlation with operative revision ... Full text Open Access Link to item Cite

Drivers of Cervical Deformity Have a Strong Influence on Achieving Optimal Radiographic and Clinical Outcomes at 1 Year After Cervical Deformity Surgery.

Journal Article World Neurosurg · April 2018 OBJECTIVE: The primary driver (PD) of cervical malalignment is important in characterizing cervical deformity (CD) and should be included in fusion to achieve alignment and quality-of-life goals. This study aims to define how PDs improve understanding of t ... Full text Open Access Link to item Cite

Frailty and Health-Related Quality of Life Improvement Following Adult Spinal Deformity Surgery.

Journal Article World Neurosurg · April 2018 BACKGROUND: Although the Adult Spinal Deformity Frailty Index (ASD-FI) predicts major complications and prolonged hospital length of stay after adult spinal deformity surgery, the impact of frailty on postoperative changes in health-related quality of life ... Full text Open Access Link to item Cite

Geographic variations in clinical presentation and outcomes of decompressive surgery in patients with symptomatic degenerative cervical myelopathy: analysis of a prospective, international multicenter cohort study of 757 patients

Journal Article Spine Journal · April 1, 2018 Background Context: Degenerative cervical myelopathy (DCM) is a progressive degenerative spine disease and the most common cause of spinal cord impairment in adults worldwide. Few studies have reported on regional variations in demographics, clinical prese ... Full text Open Access Cite

Utility of neuromonitoring during lumbar pedicle subtraction osteotomy for adult spinal deformity

Conference JOURNAL OF NEUROSURGERY · April 1, 2018 Link to item Cite

Elderly patients have worse EQ-5D outcomes after spondylolisthesis surgery than young patients, yet they are satisfied with surgery

Conference JOURNAL OF NEUROSURGERY · April 1, 2018 Link to item Cite

Under Correction of Sagittal Deformities Based on Age-adjusted Alignment Thresholds Leads to Worse Health-related Quality of Life Whereas Over Correction Provides No Additional Benefit.

Journal Article Spine (Phila Pa 1976) · March 15, 2018 STUDY DESIGN: Retrospective review of prospectively-collected database. OBJECTIVE: This study aims to compare 2-year clinical outcomes of patients who underwent surgical reconstructions based on their achievement to age-adjusted alignment ideals. SUMMARY O ... Full text Open Access Link to item Cite

Xipho-pubic angle (XPA) correlates with patient's reported outcomes in a population of adult spinal deformity: results from a multi-center cohort study.

Journal Article Eur Spine J · March 2018 STUDY DESIGN: Retrospective multi-center cohort study. PURPOSE: Sagittal misalignment causes changes in the abdominal shape. Xipho-pubic angle (XPA) has been previously described to radiographically evaluate the shape of the abdominal cavity in patients wi ... Full text Open Access Link to item Cite

A cost-effectiveness comparisons of adult spinal deformity surgery in the United States and Japan.

Journal Article Eur Spine J · March 2018 PURPOSE: Information about the cost-effectiveness of surgical procedures for adult spinal deformity (ASD) is critical for providing appropriate treatments for these patients. The purposes of this study were to compare the direct cost and cost-effectiveness ... Full text Open Access Link to item Cite

An international consensus on the appropriate evaluation and treatment for adults with spinal deformity.

Journal Article Eur Spine J · March 2018 PURPOSE: Evaluation and surgical management for adult spinal deformity (ASD) patients varies between health care providers. The purpose of this study is to identify appropriateness of specific approaches and management strategies for the treatment of ASD. ... Full text Open Access Link to item Cite

Operative Management of Adult Spinal Deformity Results in Significant Increases in QALYs Gained Compared to Nonoperative Management: Analysis of 479 Patients With Minimum 2-Year Follow-Up.

Journal Article Spine (Phila Pa 1976) · March 1, 2018 STUDY DESIGN: Retrospective review of prospective multicenter adult spinal deformity (ASD) database. OBJECTIVE: To compare the quality-adjusted life years (QALYs) between operative and nonoperative treatments for ASD patients. SUMMARY OF BACKGROUND DATA: O ... Full text Open Access Link to item Cite

Characterizing Adult Cervical Deformity and Disability Based on Existing Cervical and Adult Deformity Classification Schemes at Presentation and Following Correction.

Journal Article Neurosurgery · February 1, 2018 BACKGROUND: Adult cervical deformity (ACD) classifications have not been implemented in a prospective ACD population and in conjunction with adult spinal deformity (ASD) classifications. OBJECTIVE: To characterize cervical deformity type and malalignment w ... Full text Open Access Link to item Cite

Re-operation After Long-Segment Fusions for Adult Spinal Deformity: The Impact of Extending the Construct Below the Lumbar Spine.

Journal Article Neurosurgery · February 1, 2018 BACKGROUND: Deciding where to end a long-segment fusion for adult spinal deformity (ASD) may be a challenge, particularly in the absence of an abnormality at L5/S1. Some suggest prophylactic extension of the construct to the sacrum and/or ilium (S/I) to pr ... Full text Open Access Link to item Cite

Prospective multi-centric evaluation of upper cervical and infra-cervical sagittal compensatory alignment in patients with adult cervical deformity.

Journal Article Eur Spine J · February 2018 PURPOSE: Reciprocal mechanisms for standing alignment have been described in thoraco-lumbar deformity but have not been studied in patients with primary cervical deformity (CD). The purpose of this study is to report upper- and infra-cervical sagittal comp ... Full text Open Access Link to item Cite

Patient profiling can identify patients with adult spinal deformity (ASD) at risk for conversion from nonoperative to surgical treatment: initial steps to reduce ineffective ASD management.

Journal Article Spine J · February 2018 BACKGROUND CONTEXT: Non-operative management is a common initial treatment for patients with adult spinal deformity (ASD) despite reported superiority of surgery with regard to outcomes. Ineffective medical care is a large source of resource drain on the h ... Full text Open Access Link to item Cite

Prevalence and Indications for Unplanned Reoperations Following Index Surgery in the Adult Symptomatic Lumbar Scoliosis NIH-Sponsored Clinical Trial.

Journal Article Spine Deform · 2018 STUDY DESIGN: Longitudinal cohort. OBJECTIVE: To report on the prevalence and indications for unplanned reoperations following index surgery in the Adult Symptomatic Lumbar Scoliosis NIH-sponsored Clinical Trial. SUMMARY OF BACKGROUND DATA: Reoperation fol ... Full text Open Access Link to item Cite

Development of a Preoperative Predictive Model for Reaching the Oswestry Disability Index Minimal Clinically Important Difference for Adult Spinal Deformity Patients.

Journal Article Spine Deform · 2018 STUDY DESIGN: Retrospective review of prospective multicenter adult spinal deformity (ASD) database. OBJECTIVE: To create a model based on baseline demographic, radiographic, health-related quality of life (HRQOL), and surgical factors that can predict pat ... Full text Open Access Link to item Cite

Defining the minimum clinically important difference for grade I degenerative lumbar spondylolisthesis: insights from the Quality Outcomes Database.

Journal Article Neurosurg Focus · January 2018 OBJECTIVE Patient-reported outcomes (PROs) play a pivotal role in defining the value of surgical interventions for spinal disease. The concept of minimum clinically important difference (MCID) is considered the new standard for determining the effectivenes ... Full text Open Access Link to item Cite

Women fare best following surgery for degenerative lumbar spondylolisthesis: a comparison of the most and least satisfied patients utilizing data from the Quality Outcomes Database.

Journal Article Neurosurg Focus · January 2018 OBJECTIVE The American Association of Neurological Surgeons launched the Quality Outcomes Database (QOD), a prospective longitudinal registry that includes demographic, clinical, and patient-reported outcome (PRO) data, to measure the safety and quality of ... Full text Open Access Link to item Cite

Health-Related Quality of Life Scores Underestimate the Impact of Major Complications in Lumbar Degenerative Scoliosis Surgery.

Journal Article Spine Deform · January 2018 STUDY DESIGN: Retrospective cohort. OBJECTIVE: To examine Charlson Comorbidity Index (CCMI) as a marker for deterioration in health status not reflected in standard Health Related Quality of Life (HRQOL) measures. SUMMARY OF BACKGROUND DATA: HRQOL has beco ... Full text Open Access Link to item Cite

SRS-22R Minimum Clinically Important Difference and Substantial Clinical Benefit After Adult Lumbar Scoliosis Surgery.

Journal Article Spine Deform · January 2018 STUDY DESIGN: Longitudinal cohort. OBJECTIVES: To determine if the minimum clinically important difference (MCID) and substantial clinical benefit (SCB) thresholds for the Scoliosis Research Society-22R (SRS22R) domains in patients with degenerative lumbar ... Full text Open Access Link to item Cite

Adult Spinal Deformity Knowledge in Orthopedic Spine Surgeons: Impact of Fellowship Training, Experience, and Practice Characteristics.

Journal Article Spine Deform · January 2018 STUDY DESIGN: Survey study. OBJECTIVE: The purpose of this paper was to assess the level of adult spine deformity (ASD) knowledge among orthopedic spine surgeons and identify areas for improvement in spine surgery training. SUMMARY OF BACKGROUND DATA: ASD ... Full text Open Access Link to item Cite

Importance of Sagittal Alignment of the Cervical Spine in the Management of Degenerative Cervical Myelopathy.

Journal Article Neurosurg Clin N Am · January 2018 Cervical spine sagittal malalignment correlates with worse symptoms and outcomes in patients with degenerative cervical myelopathy (DCM), and should influence surgical management. An anterior versus posterior surgical approach may not significantly change ... Full text Open Access Link to item Cite

Assessment of a Novel Adult Cervical Deformity Frailty Index as a Component of Preoperative Risk Stratification.

Journal Article World Neurosurg · January 2018 OBJECTIVE: To determine the value of a novel adult cervical deformity frailty index (CD-FI) in preoperative risk stratification. METHODS: We reviewed a prospective, multicenter database of adults with cervical spine deformity. We selected 40 variables to c ... Full text Open Access Link to item Cite

Postoperative spinal deformities: Kyphosis, nonunion, and loss of motion segment

Chapter · January 1, 2018 Full text Cite

Patient characteristics of smokers undergoing lumbar spine surgery: an analysis from the Quality Outcomes Database.

Journal Article J Neurosurg Spine · December 2017 OBJECTIVE In this analysis the authors compare the characteristics of smokers to nonsmokers using demographic, socioeconomic, and comorbidity variables. They also investigate which of these characteristics are most strongly associated with smoking status. ... Full text Open Access Link to item Cite

Despite worse baseline status depressed patients achieved outcomes similar to those in nondepressed patients after surgery for cervical deformity.

Journal Article Neurosurg Focus · December 2017 OBJECTIVE Depression and anxiety have been demonstrated to have negative impacts on outcomes after spine surgery. In patients with cervical deformity (CD), the psychological and physiological burdens of the disease may overlap without clear boundaries. Whi ... Full text Open Access Link to item Cite

Impact of case type, length of stay, institution type, and comorbidities on Medicare diagnosis-related group reimbursement for adult spinal deformity surgery.

Journal Article Neurosurg Focus · December 2017 OBJECTIVE The aim of this study was to educate medical professionals about potential financial impacts of improper diagnosis-related group (DRG) coding in adult spinal deformity (ASD) surgery. METHODS Medicare's Inpatient Prospective Payment System PC Pric ... Full text Open Access Link to item Cite

Male sex may not be associated with worse outcomes in primary all-posterior adult spinal deformity surgery: a multicenter analysis.

Journal Article Neurosurg Focus · December 2017 OBJECTIVE Adolescent spine deformity studies have shown that male patients require longer surgery and have greater estimated blood loss (EBL) and complications compared with female patients. No studies exist to support this relationship in adult spinal def ... Full text Open Access Link to item Cite

Potential of predictive computer models for preoperative patient selection to enhance overall quality-adjusted life years gained at 2-year follow-up: a simulation in 234 patients with adult spinal deformity.

Journal Article Neurosurg Focus · December 2017 OBJECTIVE Patients with adult spinal deformity (ASD) experience significant quality of life improvements after surgery. Treatment, however, is expensive and complication rates are high. Predictive analytics has the potential to use many variables to make a ... Full text Open Access Link to item Cite

An assessment of frailty as a tool for risk stratification in adult spinal deformity surgery.

Journal Article Neurosurg Focus · December 2017 OBJECTIVE The goal of this study was to analyze the value of an adult spinal deformity frailty index (ASD-FI) in preoperative risk stratification. Preoperative risk assessment is imperative before procedures known to have high complication rates, such as A ... Full text Open Access Link to item Cite

Introduction. Adult spinal deformity.

Journal Article Neurosurg Focus · December 2017 Full text Open Access Link to item Cite

Initial Experience With Real-Time Continuous Physical Activity Monitoring in Patients Undergoing Spine Surgery.

Journal Article Clin Spine Surg · December 2017 STUDY DESIGN: Multicenter prospective pilot study. OBJECTIVE: To evaluate if continuous physical activity monitoring by a personal electronic 3-dimensional accelerometer device is feasible and can provide objective data that correlates with patient-reporte ... Full text Open Access Link to item Cite

Minimally Invasive Posterior Cervical Foraminotomy

Journal Article Clinical Spine Surgery: A Spine Publication · December 2017 Study Design:Retrospective cohort study.Objective:Assessment of outcome afte ... Full text Open Access Cite

Incidence of perioperative medical complications and mortality among elderly patients undergoing surgery for spinal deformity: analysis of 3519 patients.

Journal Article J Neurosurg Spine · November 2017 OBJECTIVE Using 2 complication-reporting methods, the authors investigated the incidence of major medical complications and mortality in elderly patients after surgery for adult spinal deformity (ASD) during a 2-year follow-up period. METHODS The authors q ... Full text Open Access Link to item Cite

Comparative analysis of perioperative complications between a multicenter prospective cervical deformity database and the Nationwide Inpatient Sample database.

Journal Article Spine J · November 2017 BACKGROUND CONTEXT: Complication rates for adult cervical deformity are poorly characterized given the complexity and heterogeneity of cases. PURPOSE: To compare perioperative complication rates following adult cervical deformity corrective surgery between ... Full text Open Access Link to item Cite

An analysis from the Quality Outcomes Database, Part 2. Predictive model for return to work after elective surgery for lumbar degenerative disease.

Journal Article J Neurosurg Spine · October 2017 OBJECTIVE Current costs associated with spine care are unsustainable. Productivity loss and time away from work for patients who were once gainfully employed contributes greatly to the financial burden experienced by individuals and, more broadly, society. ... Full text Open Access Link to item Cite

Complication rates associated with 3-column osteotomy in 82 adult spinal deformity patients: retrospective review of a prospectively collected multicenter consecutive series with 2-year follow-up.

Journal Article J Neurosurg Spine · October 2017 OBJECTIVE Although 3-column osteotomy (3CO) can provide powerful alignment correction in adult spinal deformity (ASD), these procedures are complex and associated with high complication rates. The authors' objective was to assess complications associated w ... Full text Open Access Link to item Cite

An analysis from the Quality Outcomes Database, Part 1. Disability, quality of life, and pain outcomes following lumbar spine surgery: predicting likely individual patient outcomes for shared decision-making.

Journal Article J Neurosurg Spine · October 2017 OBJECTIVE Quality and outcomes registry platforms lie at the center of many emerging evidence-driven reform models. Specifically, clinical registry data are progressively informing health care decision-making. In this analysis, the authors used data from a ... Full text Open Access Link to item Cite

Proximal Junctional Kyphosis Prevention Strategies: A Video Technique Guide.

Journal Article Oper Neurosurg (Hagerstown) · October 1, 2017 BACKGROUND: Proximal junctional kyphosis (PJK) is a well-recognized complication in patients undergoing posterior instrumented fusion procedures for adult spinal deformity. Strategies that reduce rates of PJK have the potential to improve the safety of the ... Full text Open Access Link to item Cite

Comparing Quality of Life in Cervical Spondylotic Myelopathy with Other Chronic Debilitating Diseases Using the Short Form Survey 36-Health Survey.

Journal Article World Neurosurg · October 2017 BACKGROUND: Although cervical spondylotic myelopathy (CSM) can be devastating, its relative impact on general health remains unclear. Patient responses to the Short Form Survey 36-Health Survey (SF-36) Physical Component Summary (PCS)/Mental Component Summ ... Full text Open Access Link to item Cite

Is There a Patient Profile That Characterizes a Patient With Adult Spinal Deformity as a Candidate for Minimally Invasive Surgery?

Journal Article Global Spine J · October 2017 STUDY DESIGN: Retrospective review. OBJECTIVES: The goal of this study was to evaluate the baseline characteristics of patients chosen to undergo traditional open versus minimally invasive surgery (MIS) for adult spinal deformity (ASD). METHODS: A multicen ... Full text Open Access Link to item Cite

The Fate of Patients with Adult Spinal Deformity Incurring Rod Fracture After Thoracolumbar Fusion.

Journal Article World Neurosurg · October 2017 OBJECTIVE: To report the outcome of adult spinal deformity (ASD) in patients with rod fracture (RF) after thoracolumbar fusion. METHODS: Retrospective review of prospective, multicenter database. Operative patients with ASD ≥18 years old with RF after ASD ... Full text Open Access Link to item Cite

In-Hospital Complications and Resource Utilization Following Lumbar Spine Surgery in Patients with Parkinson Disease: Evaluation of the National Inpatient Sample Database.

Journal Article World Neurosurg · October 2017 BACKGROUND: Previous reports suggest that patients with Parkinson disease (PD) have elevated rates of complications following spine surgery; however, these reports are limited by small patient series. In this study, we used the National Inpatient Sample (N ... Full text Open Access Link to item Cite

Importance of patient-reported individualized goals when assessing outcomes for adult spinal deformity (ASD): initial experience with a Patient Generated Index (PGI).

Journal Article Spine J · October 2017 BACKGROUND CONTEXT: Current metrics to assess patients' health-related quality of life (HRQOL) may not reflect a true change in the patients' specific perception of what is most important to them. PURPOSE: This study aimed to describe the initial experienc ... Full text Open Access Link to item Cite

Achieving Optimal Outcome for Degenerative Lumbar Spondylolisthesis: Randomized Controlled Trial Results.

Conference Neurosurgery · September 1, 2017 Full text Link to item Cite

Timing of Decompression in Patients With Acute Spinal Cord Injury: A Systematic Review.

Journal Article Global Spine J · September 2017 STUDY DESIGN: Systematic review. OBJECTIVE: To conduct a systematic review and synthesis of the literature to assess the comparative effectiveness, safety, and cost-effectiveness of early (≤24 hours) versus late decompression (>24 hours) in adults with acu ... Full text Open Access Link to item Cite

Predictors of Hospital Readmission and Surgical Site Infection in the United States, Denmark, and Japan: Is Risk Stratification a Universal Language?

Journal Article Spine (Phila Pa 1976) · September 1, 2017 STUDY DESIGN: Retrospective review of three spine surgery databases. OBJECTIVES: The purpose of the present study is to determine whether predictors of hospital readmission and surgical site infection (SSI) after lumbar fusion will be the same in United St ... Full text Open Access Link to item Cite

Risk factors for 30-day reoperation and 3-month readmission: analysis from the Quality and Outcomes Database lumbar spine registry.

Journal Article J Neurosurg Spine · August 2017 OBJECTIVE The aim of this paper was to use a prospective, longitudinal, multicenter outcome registry of patients undergoing surgery for lumbar degenerative disease in order to assess the incidence and factors associated with 30-day reoperation and 90-day r ... Full text Open Access Link to item Cite

Minimally invasive versus open fusion for Grade I degenerative lumbar spondylolisthesis: analysis of the Quality Outcomes Database.

Journal Article Neurosurg Focus · August 2017 OBJECTIVE Lumbar spondylolisthesis is a degenerative condition that can be surgically treated with either open or minimally invasive decompression and instrumented fusion. Minimally invasive surgery (MIS) approaches may shorten recovery, reduce blood loss, ... Full text Open Access Link to item Cite

Novel Angular Measures of Cervical Deformity Account for Upper Cervical Compensation and Sagittal Alignment.

Journal Article Clin Spine Surg · August 2017 STUDY DESIGN: This is a retrospective review of a prospective multicenter database. OBJECTIVE: This study introduces 2 new cervical alignment measures accounting for both cervical deformity (CD) and upper cervical compensation. SUMMARY OF BACKGROUND DATA: ... Full text Open Access Link to item Cite

A Novel Tool for Deformity Surgery Planning: Determining the Magnitude of Lordotic Correction Required to Achieve a Desired Sagittal Vertical Axis.

Journal Article World Neurosurg · August 2017 OBJECTIVE: We sought to create a model capable of predicting the magnitude of pelvic incidence-lumbar lordosis (PI-LL) correction necessary to achieve a desired change in sagittal vertical axis (SVA). METHODS: A retrospective review was conducted of a pros ... Full text Open Access Link to item Cite

Three-column osteotomy for correction of cervical and cervicothoracic deformities: alignment changes and early complications in a multicenter prospective series of 23 patients.

Journal Article Eur Spine J · August 2017 PURPOSE: Three-column osteotomy (3CO), including pedicle subtraction osteotomy (PSO) and vertebral column resection (VCR), can provide powerful alignment correction for adult cervical deformity (ACD). Our objective was to assess alignment changes and early ... Full text Open Access Link to item Cite

Magnitude, Location, and Factors Related to Regional and Global Sagittal Alignment Change in Long Adult Deformity Constructs: Report of 183 Patients With 2-Year Follow-up.

Journal Article Clin Spine Surg · August 2017 STUDY DESIGN: This is a retrospective review of a prospective multicenter adult spinal deformity (ASD) database. OBJECTIVE: To quantify the location and magnitude of sagittal alignment changes within instrumented and noninstrumented spinal segments and to ... Full text Open Access Link to item Cite

Stiffness After Pan-Lumbar Arthrodesis for Adult Spinal Deformity Does Not Significantly Impact Patient Functional Status or Satisfaction Irrespective of Proximal Endpoint.

Journal Article Spine (Phila Pa 1976) · August 1, 2017 STUDY DESIGN: Prospective, multicenter. OBJECTIVE: To determine if stiffness significantly affects function or satisfaction after pan-lumbar arthrodesis. SUMMARY OF BACKGROUND DATA: The Lumbar Stiffness Disability Index (LSDI) is a validated measure of the ... Full text Open Access Link to item Cite

Retrospective analysis underestimates neurological deficits in complex spinal deformity surgery: a Scoli-RISK-1 Study.

Journal Article J Neurosurg Spine · July 2017 OBJECTIVE The authors conducted a study to compare neurological deficit rates associated with complex adult spinal deformity (ASD) surgery when recorded in retrospective and prospective studies. Retrospective studies may underreport neurological deficits d ... Full text Open Access Link to item Cite

Cell Saver for Adult Spinal Deformity Surgery Reduces Cost.

Journal Article Spine Deform · July 2017 STUDY DESIGN: Retrospective cohort. OBJECTIVES: To determine if the use of cell saver reduces overall blood costs in adult spinal deformity (ASD) surgery. SUMMARY OF BACKGROUND DATA: Recent studies have questioned the clinical value of cell saver during sp ... Full text Open Access Link to item Cite

Adult Scoliosis Deformity Surgery: Comparison of Outcomes Between One Versus Two Attending Surgeons.

Journal Article Spine (Phila Pa 1976) · July 1, 2017 STUDY DESIGN: Retrospective review of prospectively collected data. OBJECTIVE: Assess outcomes of adult spinal deformity (ASD) surgery performed by one versus two attending surgeons. SUMMARY OF BACKGROUND DATA: ASD centers have developed two attending team ... Full text Open Access Link to item Cite

Poor Nutrition Status and Lumbar Spine Fusion Surgery in the Elderly: Readmissions, Complications, and Mortality.

Journal Article Spine (Phila Pa 1976) · July 1, 2017 STUDY DESIGN: Retrospective database review. OBJECTIVE: To quantify the medical and surgical risks associated with elective lumbar spine fusion surgery in patients with poor preoperative nutritional status and to assess how nutritional status alters length ... Full text Open Access Link to item Cite

Development of a preoperative predictive model for major complications following adult spinal deformity surgery.

Journal Article J Neurosurg Spine · June 2017 OBJECTIVE The operative management of patients with adult spinal deformity (ASD) has a high complication rate and it remains unknown whether baseline patient characteristics and surgical variables can predict early complications (intraoperative and periope ... Full text Open Access Link to item Cite

Early Patient-Reported Outcomes Predict 3-Year Outcomes in Operatively Treated Patients with Adult Spinal Deformity.

Journal Article World Neurosurg · June 2017 BACKGROUND: For patients with adult spinal deformity (ASD), surgical treatment may improve their health-related quality of life. This study investigates when the greatest improvement in outcomes occurs and whether incremental improvements in patient-report ... Full text Open Access Link to item Cite

Selecting caudal fusion levels: 2 year functional and stiffness outcomes with matched pairs analysis in multilevel fusion to L5 versus S1.

Journal Article Eur Spine J · June 2017 PURPOSE: Controversy persists as to whether to end multilevel thoracolumbar fusions caudally at L5 or S1. Some argue that stopping at L5 may preserve greater function, but there are few data comparing functional limitations due to lumbar stiffness in patie ... Full text Open Access Link to item Cite

Patient Satisfaction After Adult Spinal Deformity Surgery Does Not Strongly Correlate With Health-Related Quality of Life Scores, Radiographic Parameters, or Occurrence of Complications.

Journal Article Spine (Phila Pa 1976) · May 15, 2017 STUDY DESIGN: This is a multicenter retrospective review of prospectively collected cases. OBJECTIVE: Our objective was to evaluate the relationship between patient satisfaction, health-related quality of life (HRQoL) scores, complications, and radiographi ... Full text Open Access Link to item Cite

The Health Impact of Adult Cervical Deformity in Patients Presenting for Surgical Treatment: Comparison to United States Population Norms and Chronic Disease States Based on the EuroQuol-5 Dimensions Questionnaire.

Journal Article Neurosurgery · May 1, 2017 BACKGROUND: Although adult cervical spine deformity (ACSD) is associated with pain and disability, its health impact has not been quantified in comparison to other chronic diseases. OBJECTIVE: To perform a comparative analysis of the health impact of sympt ... Full text Open Access Link to item Cite

A Multicenter Evaluation of Clinical and Radiographic Outcomes Following High-grade Spondylolisthesis Reduction and Fusion.

Journal Article Clin Spine Surg · May 2017 OBJECTIVE: A retrospective review of the clinical and radiographic outcomes from a multicenter study of surgical treatment for high-grade spondylolisthesis (HGS) in adults. The objective was to assess the safety of surgical reduction, its ability to correc ... Full text Open Access Link to item Cite

Esophageal Perforation Following Anterior Cervical Spine Surgery: Case Report and Review of the Literature.

Journal Article Global Spine J · April 2017 STUDY DESIGN: Multicenter retrospective case series and review of the literature. OBJECTIVE: To determine the rate of esophageal perforations following anterior cervical spine surgery. METHODS: As part of an AOSpine series on rare complications, a retrospe ... Full text Open Access Link to item Cite

A Multicenter Study of the Presentation, Treatment, and Outcomes of Cervical Dural Tears.

Journal Article Global Spine J · April 2017 STUDY DESIGN: Retrospective multicenter case series study. OBJECTIVE: Because cervical dural tears are rare, most surgeons have limited experience with this complication. A multicenter study was performed to better understand the presentation, treatment, a ... Full text Open Access Link to item Cite

Rare Complications of Cervical Spine Surgery: Horner's Syndrome.

Journal Article Global Spine J · April 2017 STUDY DESIGN: A multicenter retrospective case series. OBJECTIVE: Horner's syndrome is a known complication of anterior cervical spinal surgery, but it is rarely encountered in clinical practice. To better understand the incidence, risks, and neurologic ou ... Full text Open Access Link to item Cite

Rare Complications of Cervical Spine Surgery: Pseudomeningocoele.

Journal Article Global Spine J · April 2017 STUDY DESIGN: This study was a retrospective, multicenter cohort study. OBJECTIVES: Rare complications of cervical spine surgery are inherently difficult to investigate. Pseudomeningocoele (PMC), an abnormal collection of cerebrospinal fluid that communica ... Full text Open Access Link to item Cite

A Multicenter Review of Superior Laryngeal Nerve Injury Following Anterior Cervical Spine Surgery.

Journal Article Global Spine J · April 2017 STUDY DESIGN: A retrospective multicenter case-series study; case report and review of the literature. OBJECTIVE: The anatomy and function of the superior laryngeal nerve (SLN) are well described; however, the consequences of SLN injury remain variable and ... Full text Open Access Link to item Cite

Neurologic Deficits Have a Negative Impact on Patient-Related Outcomes in Primary Presentation Adult Symptomatic Lumbar Scoliosis Surgical Treatment at One-Year Follow-up.

Journal Article Spine (Phila Pa 1976) · April 1, 2017 STUDY DESIGN: A retrospective analysis of prospective, multicenter National Institute of Health clinical trial. OBJECTIVE: The aim of this study was to assess the rate of neurologic complications and impact of new neurologic deficits on 1-year postoperativ ... Full text Open Access Link to item Cite

Cervical sagittal deformity develops after PJK in adult thoracolumbar deformity correction: radiographic analysis utilizing a novel global sagittal angular parameter, the CTPA.

Journal Article Eur Spine J · April 2017 PURPOSE: To describe reciprocal changes in cervical alignment after adult spinal deformity (ASD) correction and subsequent development of proximal junctional kyphosis (PJK). This study also investigated these changes using two novel global sagittal angular ... Full text Open Access Link to item Cite

Does Myelopathy or Alignment Improvement Drive Acute Post-Operative Outcomes in Cervical Deformity Patients?

Conference JOURNAL OF NEUROSURGERY · April 1, 2017 Link to item Cite

Frail Patients Achieve Greater Health Related Quality of Life Improvement Following Adult Spinal Deformity Surgery

Conference JOURNAL OF NEUROSURGERY · April 1, 2017 Link to item Cite

Recent and Emerging Advances in Spinal Deformity.

Journal Article Neurosurgery · March 1, 2017 BACKGROUND: Over the last several decades, significant advances have occurred in the assessment and management of spinal deformity. OBJECTIVE: The primary focus of this narrative review is on recent advances in adult thoracic, thoracolumbar, and lumbar def ... Full text Open Access Link to item Cite

Predictors of Health-Related Quality-of-Life After Complex Adult Spinal Deformity Surgery: A Scoli-RISK-1 Secondary Analysis.

Journal Article Spine Deform · March 2017 STUDY DESIGN: Longitudinal cohort. OBJECTIVES: To identify variables that predict 2-year Short Form-36 Physical Composite Summary Score (SF-36PCS) and the Scoliosis Research Society-22R (SRS22-R) Total score after surgery for complex adult spinal deformity ... Full text Open Access Link to item Cite

Comparison of Structural Disease Burden to Health-related Quality of Life Scores in 264 Adult Spinal Deformity Patients With 2-Year Follow-up: Novel Insights into Drivers of Disability.

Journal Article Clin Spine Surg · March 2017 STUDY DESIGN: This is a review of a prospective multicenter database. OBJECTIVE: To investigate the relationship between preoperative disability and sagittal deformity in patients with high Oswestry Disability Index (ODI) and no sagittal malalignment, or l ... Full text Open Access Link to item Cite

Commentary: Appropriate Use Criteria for Lumbar Degenerative Scoliosis: Developing Evidence-based Guidance for Complex Treatment Decisions.

Journal Article Neurosurgery · March 1, 2017 Lumbar degenerative scoliosis is a relatively common problem, and is being treated more frequently due to the confluence of an aging population and an increased capacity and willingness to manage difficult problems in older patients. Lumbar degenerative sc ... Full text Open Access Link to item Cite

Does MIS Surgery Allow for Shorter Constructs in the Surgical Treatment of Adult Spinal Deformity?

Journal Article Neurosurgery · March 1, 2017 BACKGROUND: The length of construct can potentially influence perioperative risks in adult spinal deformity (ASD) surgery. A head-to-head comparison between open and minimally invasive surgery (MIS) techniques for treatment of ASD has yet to be performed. ... Full text Open Access Link to item Cite

Randomized controlled trials for degenerative lumbar spondylolisthesis: which patients benefit from lumbar fusion?

Journal Article J Neurosurg Spine · February 2017 Full text Open Access Link to item Cite

Utility of multilevel lateral interbody fusion of the thoracolumbar coronal curve apex in adult deformity surgery in combination with open posterior instrumentation and L5-S1 interbody fusion: a case-matched evaluation of 32 patients.

Journal Article J Neurosurg Spine · February 2017 OBJECTIVE The aim of this study was to evaluate the utility of supplementing long thoracolumbar posterior instrumented fusion (posterior spinal fusion, PSF) with lateral interbody fusion (LIF) of the lumbar/thoracolumbar coronal curve apex in adult spinal ... Full text Open Access Link to item Cite

Impact of obesity on complications and outcomes: a comparison of fusion and nonfusion lumbar spine surgery.

Journal Article J Neurosurg Spine · February 2017 OBJECTIVE Prior studies have shown obesity to be associated with higher complication rates but equivalent clinical outcomes following lumbar spine surgery. These findings have been reproducible across lumbar spine surgery in general and for lumbar fusion s ... Full text Open Access Link to item Cite

Sagittal plane deformity surgery (VCR) complication

Chapter · January 1, 2017 Surgery for adult spinal deformity (ASD) remains a technically challenging undertaking. Improvements in surgical techniques, instrumentation, and perioperative management have enabled correction of increasingly more complex multiplanar deformities. The sur ... Full text Cite

Sacral insufficiency fracture surgery complication

Chapter · January 1, 2017 Sacral insufficiency fractures are a relatively uncommon complication following lumbosacral instrumented arthrodesis. Risk factors for developing an insufficiency fracture include osteopenia/osteoporosis, increased body mass index, an increased pelvic inci ... Full text Cite

The effect of posterior polyester tethers on the biomechanics of proximal junctional kyphosis: a finite element analysis.

Journal Article J Neurosurg Spine · January 2017 OBJECTIVE Proximal junctional kyphosis (PJK) remains problematic following multilevel instrumented spine surgery. Previous biomechanical studies indicate that providing less rigid fixation at the cranial aspect of a long posterior instrumented construct, v ... Full text Open Access Link to item Cite

Impact of poor mental health in adult spinal deformity patients with poor physical function: a retrospective analysis with a 2-year follow-up.

Journal Article J Neurosurg Spine · January 2017 OBJECTIVE Mental disease burden can have a significant impact on levels of disability and health-related quality of life (HRQOL) measures. Therefore, the authors investigated the significance of mental health status in adults with spinal deformity and poor ... Full text Open Access Link to item Cite

Impact of cost valuation on cost-effectiveness in adult spine deformity surgery.

Journal Article Spine J · January 2017 BACKGROUND CONTEXT: Over the past decade, the number of adult spinal deformity (ASD) surgeries has more than doubled in the United States. The complex surgeries needed to manage ASD are associated with significant resource utilization and high cost, making ... Full text Open Access Link to item Cite

Baseline Patient-Reported Outcomes Correlate Weakly With Radiographic Parameters: A Multicenter, Prospective NIH Adult Symptomatic Lumbar Scoliosis Study of 286 Patients.

Journal Article Spine (Phila Pa 1976) · November 15, 2016 STUDY DESIGN: Prospective, cross-sectional study. OBJECTIVE: The aim of the study was to determine which radiographic parameters drive patient-reported outcomes (PROs) in primary presentation adult symptomatic lumbar scoliosis (ASLS). SUMMARY OF BACKGROUND ... Full text Open Access Link to item Cite

Medical Complications After Adult Spinal Deformity Surgery: Incidence, Risk Factors, and Clinical Impact.

Journal Article Spine (Phila Pa 1976) · November 15, 2016 STUDY DESIGN: Retrospective review of a prospective multicenter database evaluating surgical adult spinal deformity (ASD) patients. OBJECTIVE: This study aims to identify risk factors for medical complications in ASD patients undergoing surgery. SUMMARY OF ... Full text Open Access Link to item Cite

Development of Validated Computer-based Preoperative Predictive Model for Proximal Junction Failure (PJF) or Clinically Significant PJK With 86% Accuracy Based on 510 ASD Patients With 2-year Follow-up.

Journal Article Spine (Phila Pa 1976) · November 15, 2016 STUDY DESIGN: A retrospective review of large, multicenter adult spinal deformity (ASD) database. OBJECTIVE: The aim of this study was to build a model based on baseline demographic, radiographic, and surgical factors that can predict clinically significan ... Full text Open Access Link to item Cite

Response

Journal Article Journal of Neurosurgery: Spine · November 1, 2016 Full text Open Access Cite

Impact of preoperative depression on 2-year clinical outcomes following adult spinal deformity surgery: the importance of risk stratification based on type of psychological distress.

Journal Article J Neurosurg Spine · October 2016 OBJECTIVE The objective of this study was to isolate whether the effect of a baseline clinical history of depression on outcome is independent of associated physical disability and to evaluate which mental health screening tool has the most utility in dete ... Full text Open Access Link to item Cite

Validity, Reliability, and Responsiveness of SRS-7 as an Outcomes Assessment Instrument for Operatively Treated Patients With Adult Spinal Deformity.

Journal Article Spine (Phila Pa 1976) · September 15, 2016 STUDY DESIGN: A retrospective analysis. OBJECTIVE: The aim of our study was to compare the normality, concurrent validity, internal consistency, responsiveness, and dimensionality of an item response theory-derived seven-question instrument (SRS-7), agains ... Full text Open Access Link to item Cite

Complications of surgical intervention in adult lumbar scoliosis

Journal Article Current Reviews in Musculoskeletal Medicine · September 1, 2016 If nonoperative measures are unsuccessful in managing the pain and disability of adult spinal deformities, surgical correction may provide the potential for significant improvement in a patient’s quality of life. However, these procedures have a relatively ... Full text Open Access Cite

Hospital Readmission Within 2 Years Following Adult Thoracolumbar Spinal Deformity Surgery: Prevalence, Predictors, and Effect on Patient-derived Outcome Measures.

Journal Article Spine (Phila Pa 1976) · September 2016 STUDY DESIGN: A retrospective review of prospective multicenter database. OBJECTIVE: The aim of this study was to identify factors influencing readmission, reoperation, and the impact on health-related quality of life outcomes (HRQoLs) in adult spinal defo ... Full text Open Access Link to item Cite

Prospective Multicenter Assessment of Early Complication Rates Associated With Adult Cervical Deformity Surgery in 78 Patients.

Journal Article Neurosurgery · September 2016 BACKGROUND: Few reports have focused on treatment of adult cervical deformity (ACD). OBJECTIVE: To present early complication rates associated with ACD surgery. METHODS: A prospective multicenter database of consecutive operative ACD patients was reviewed ... Full text Open Access Link to item Cite

Outcomes of Operative and Nonoperative Treatment for Adult Spinal Deformity

Journal Article Neurosurgery · September 2016 Full text Open Access Cite

166 Predictive Modeling of Length of Hospital Stay Following Adult Spinal Deformity Correction: Analysis of 653 Patients With an Accuracy of 75% Within 2 Days

Journal Article Neurosurgery · August 1, 2016 INTRODUCTION: The length of stay (LOS) following adult spinal deformity (ASD) surgery is a critical time period allowing for recovery to levels safe enough to return home or to rehabilitation. Thus, the goal is to minimize it for conserving hospital resour ... Full text Open Access Cite

148 Predictive Model for Return to Work After Elective Surgery for Lumbar Degenerative Disease: An Analysis From National Neurosurgery Quality Outcomes Database Registry

Journal Article Neurosurgery · August 1, 2016 INTRODUCTION: The current costs associated with spine care are unsustainable. The productivity loss and time away from work in gainfully employed patients contributes greatly to the financial burden. Therefore, it is vital to identify the factors associate ... Full text Open Access Cite

Minimally Invasive Spine Surgery and Sagittal Correction

Conference Neurosurgery · August 1, 2016 Full text Cite

How to predict return to work after lumbar discectomy: answers from the NeuroPoint-SD registry.

Conference J Neurosurg Spine · August 2016 OBJECTIVE To date, the factors that predict whether a patient returns to work after lumbar discectomy are poorly understood. Information on postoperative work status is important in analyzing the cost-effectiveness of the procedure. METHODS An observationa ... Full text Link to item Cite

A comparative analysis of the prevalence and characteristics of cervical malalignment in adults presenting with thoracolumbar spine deformity based on variations in treatment approach over 2 years.

Journal Article Eur Spine J · August 2016 PURPOSE: Characteristics specific to cervical deformity (CD) concomitant with adult thoracolumbar deformity (TLD) remains uncertain, particularly regarding treatment. This study identifies cervical malalignment prevalence following surgical and conservativ ... Full text Open Access Link to item Cite

Reoperation rates in minimally invasive, hybrid and open surgical treatment for adult spinal deformity with minimum 2-year follow-up.

Journal Article Eur Spine J · August 2016 INTRODUCTION: Minimally invasive surgical (MIS) techniques are gaining popularity in the treatment of adult spinal deformity (ASD). The premise is that MIS techniques will lead to equivalent outcomes and a reduction in perioperative complications when comp ... Full text Open Access Link to item Cite

Long-Segment Fusion for Adult Spinal Deformity Correction Using Low-Dose Recombinant Human Bone Morphogenetic Protein-2: A Retrospective Review of Fusion Rates.

Journal Article Neurosurgery · August 2016 BACKGROUND: Although use of very high-dose recombinant human bone morphogenetic protein-2 (rhBMP-2) has been reported to markedly improve fusion rates in adult spinal deformity (ASD) surgery, most centers use much lower doses due to cost constraints. How e ... Full text Open Access Link to item Cite

Patients with spinal deformity over the age of 75: a retrospective analysis of operative versus non-operative management.

Journal Article Eur Spine J · August 2016 PURPOSE: The goal of the present study was to compare the outcomes of operative and non-operative patients with adult spinal deformity (ASD) over 75 years of age. METHODS: A retrospective review of a multicenter prospective adult spinal deformity database ... Full text Open Access Link to item Cite

Recovery following adult spinal deformity surgery: the effect of complications and reoperation in 149 patients with 2-year follow-up.

Journal Article Eur Spine J · August 2016 PURPOSE: To identify the effect of complications and reoperation on the recovery process following adult spinal deformity (ASD) surgery by examining health-related quality of life (HRQOL) measures over time via an integrated health state analysis (IHS). ME ... Full text Open Access Link to item Cite

Effect of Antifibrinolytic Therapy on Complications, Thromboembolic Events, Blood Product Utilization, and Fusion in Adult Spinal Deformity Surgery.

Journal Article Spine (Phila Pa 1976) · July 15, 2016 STUDY DESIGN: A multicenter, prospective, consecutive database of surgical patients with adult spinal deformity (ASD). OBJECTIVE: This study investigated the use of antifibrinolytic (AF) therapy in ASD surgery. SUMMARY OF BACKGROUND DATA: AF therapy has be ... Full text Open Access Link to item Cite

Treatment of Axis Body Fractures: A Systematic Review.

Journal Article Clin Spine Surg · July 14, 2016 STUDY DESIGN: Evidence based systematic review. OBJECTIVE: To define the optimal treatment of fractures involving the C2 body, including those with concomitant injuries, based upon a systematic review of the literature. SUMMARY OF BACKGROUND DATA: Axis bod ... Full text Open Access Link to item Cite

Clinical and radiographic parameters associated with best versus worst clinical outcomes in minimally invasive spinal deformity surgery.

Journal Article J Neurosurg Spine · July 2016 OBJECTIVE Minimally invasive surgery (MIS) techniques are increasingly used to treat adult spinal deformity. However, standard minimally invasive spinal deformity techniques have a more limited ability to restore sagittal balance and match the pelvic incid ... Full text Open Access Link to item Cite

Prospective multicenter assessment of perioperative and minimum 2-year postoperative complication rates associated with adult spinal deformity surgery.

Journal Article J Neurosurg Spine · July 2016 OBJECTIVE Although multiple reports have documented significant benefit from surgical treatment of adult spinal deformity (ASD), these procedures can have high complication rates. Previously reported complications rates associated with ASD surgery are limi ... Full text Open Access Link to item Cite

Adult Spinal Deformity Surgeons Are Unable to Accurately Predict Postoperative Spinal Alignment Using Clinical Judgment Alone

Journal Article Spine Deformity · July 1, 2016 Object Adult spinal deformity (ASD) surgery seeks to reduce disability and improve quality of life through restoration of spinal alignment. In particular, correction of sagittal malalignment is correlated with patient outcome. Inadequate correction of sagi ... Full text Open Access Cite

Assessment of Surgical Treatment Strategies for Moderate to Severe Cervical Spinal Deformity Reveals Marked Variation in Approaches, Osteotomies, and Fusion Levels.

Journal Article World Neurosurg · July 2016 OBJECTIVE: Although previous reports suggest that surgery can improve the pain and disability of cervical spinal deformity (CSD), techniques are not standardized. Our objective was to assess for consensus on recommended surgical plans for CSD treatment. ME ... Full text Open Access Link to item Cite

Outcomes of Operative and Nonoperative Treatment for Adult Spinal Deformity: A Prospective, Multicenter, Propensity-Matched Cohort Assessment With Minimum 2-Year Follow-up.

Journal Article Neurosurgery · June 2016 BACKGROUND: High-quality studies that compare operative and nonoperative treatment for adult spinal deformity (ASD) are needed. OBJECTIVE: To compare outcomes of operative and nonoperative treatment for ASD. METHODS: This is a multicenter, prospective anal ... Full text Open Access Link to item Cite

Assessment of Impact of Long-Cassette Standing X-Rays on Surgical Planning for Cervical Pathology: An International Survey of Spine Surgeons.

Journal Article Neurosurgery · May 2016 BACKGROUND: Understanding the role of regional segments of the spine in maintaining global balance has garnered significant attention recently. Long-cassette radiographs (LCR) are necessary to evaluate global spinopelvic alignment. However, it is unclear h ... Full text Open Access Link to item Cite

Predictors of Revision Surgical Procedure Excluding Wound Complications in Adult Spinal Deformity and Impact on Patient-Reported Outcomes and Satisfaction: A Two-Year Follow-up.

Journal Article J Bone Joint Surg Am · April 6, 2016 BACKGROUND: The surgical procedure to treat adult spinal deformity is challenging, with high rates of complications, including revision procedures performed to repair instrumentation failure or unplanned surgical complications. This study quantifies the in ... Full text Open Access Link to item Cite

Prevalence and type of cervical deformities among adults with Parkinson's disease: a cross-sectional study.

Journal Article J Neurosurg Spine · April 2016 OBJECT: To identify the characteristics of cervical deformities in Parkinson's disease (PD) and the role of severity of PD in the development of cervical spine deformities, the authors investigated the prevalence of the cervical deformities, cervical kypho ... Full text Open Access Link to item Cite

Visual loss after corrective surgery for pediatric scoliosis: incidence and risk factors from a nationwide database.

Journal Article Spine J · April 2016 BACKGROUND CONTEXT: Perioperative visual loss (POVL) after spinal deformity surgery is an uncommon but severe complication. Data on the incidence and risk factors of this complication after corrective surgery in the pediatric population are limited. PURPOS ... Full text Open Access Link to item Cite

Comparison of early and late complications after minimally invasive and hybrid adult spinal deformity surgery

Conference JOURNAL OF NEUROSURGERY · April 1, 2016 Link to item Cite

Development of a Preoperative Predictive Model for Intra- or Peri-operative Major Complications with High Accuracy Validated with 558 ASD Patients

Conference JOURNAL OF NEUROSURGERY · April 1, 2016 Link to item Cite

Comparison of Complications and Clinical and Radiographic Outcomes Between Nonobese and Obese Patients with Adult Spinal Deformity Undergoing Minimally Invasive Surgery.

Journal Article World Neurosurg · March 2016 OBJECTIVE: Obesity can be associated with increased complications and potentially worse outcomes. We aimed to evaluate the impact of obesity on complications and outcomes in patients with adult spinal deformity (ASD) who underwent minimally invasive surger ... Full text Open Access Link to item Cite

Surgical considerations for major deformity correction spine surgery.

Journal Article Best Pract Res Clin Anaesthesiol · March 2016 Spinal deformity is defined as abnormality in alignment, formation, or curvature of one or more segments of the spine. Its characteristic clinical presentation and radiographic appearance differ according to patient age and the underlying cause. The most c ... Full text Open Access Link to item Cite

Patient Factors That Influence Decision Making: Randomization Versus Observational Nonoperative Versus Observational Operative Treatment for Adult Symptomatic Lumbar Scoliosis.

Journal Article Spine (Phila Pa 1976) · March 2016 STUDY DESIGN: A prospective study with randomized and observational cohorts. OBJECTIVE: The aim of this study was to determine baseline variables affecting adult symptomatic lumbar scoliosis (ASLS) decision making to participate in randomization (RAND), ob ... Full text Open Access Link to item Cite

Nonoperative Management in Neurologically Intact Thoracolumbar Burst Fractures: Clinical and Radiographic Outcomes.

Journal Article Spine (Phila Pa 1976) · March 2016 STUDY DESIGN: Retrospective cohort study. OBJECTIVE: The identification of factors that lead to the failure of nonoperative management in neurologically intact thoracolumbar burst fractures. SUMMARY OF BACKGROUND DATA: The treatment of thoracolumbar burst ... Full text Open Access Link to item Cite

Treatment of isolated cervical facet fractures: A systematic review

Journal Article Journal of Neurosurgery: Spine · February 1, 2016 OBJECTIVE: In this clinically based systematic review of cervical facet fractures, the authors' aim was to determine the optimal clinical care for patients with isolated fractures of the cervical facets through a systematic review. METHODS: A systematic re ... Full text Open Access Cite

The Clinical Correlation of the Hart-ISSG Proximal Junctional Kyphosis Severity Scale With Health-Related Quality-of-life Outcomes and Need for Revision Surgery.

Journal Article Spine (Phila Pa 1976) · February 2016 STUDY DESIGN: Retrospective analysis of prospective data. OBJECTIVE: Evaluate the utility of the Hart-International Spine Study Group proximal junctional kyphosis severity scale (Hart-ISSG PJKSS). SUMMARY OF BACKGROUND DATA: Proximal junctional kyphosis (P ... Full text Open Access Link to item Cite

Neurologic Outcomes of Complex Adult Spinal Deformity Surgery: Results of the Prospective, Multicenter Scoli-RISK-1 Study.

Journal Article Spine (Phila Pa 1976) · February 2016 STUDY DESIGN: Prospective, multicenter, international observational study. OBJECTIVE: To evaluate motor neurologic outcomes in patients undergoing surgery for complex adult spinal deformity (ASD). SUMMARY OF BACKGROUND DATA: The neurologic outcomes after s ... Full text Open Access Link to item Cite

The Health Impact of Symptomatic Adult Spinal Deformity: Comparison of Deformity Types to United States Population Norms and Chronic Diseases.

Journal Article Spine (Phila Pa 1976) · February 2016 STUDY DESIGN: A retrospective analysis of a prospective, multicenter database. OBJECTIVE: The aim of this study was to evaluate the health impact of symptomatic adult spinal deformity (SASD) by comparing Standard Form Version 2 (SF-36) scores for SASD with ... Full text Open Access Link to item Cite

Can a Minimal Clinically Important Difference Be Achieved in Elderly Patients with Adult Spinal Deformity Who Undergo Minimally Invasive Spinal Surgery?

Journal Article World Neurosurg · February 2016 BACKGROUND: Older age has been considered a relative contraindication to complex spinal procedures. Minimally invasive surgery (MIS) techniques to treat patients with adult spinal deformity (ASD) have emerged with the potential benefit of decreased approac ... Full text Open Access Link to item Cite

Effectiveness of preoperative autologous blood donation for protection against allogeneic blood exposure in adult spinal deformity surgeries: a propensity-matched cohort analysis.

Journal Article J Neurosurg Spine · January 2016 OBJECTIVE: The goal of this study was to examine the effectiveness of preoperative autologous blood donation (PABD) in adult spinal deformity (ASD) surgery. METHODS: Patients undergoing single-stay ASD reconstructions were identified in a multicenter datab ... Full text Open Access Link to item Cite

Association between preoperative cervical sagittal deformity and inferior outcomes at 2-year follow-up in patients with adult thoracolumbar deformity: analysis of 182 patients.

Journal Article J Neurosurg Spine · January 2016 OBJECTIVE: A high prevalence of cervical deformity (CD) has been identified among adult patients with thoracolumbar spinal deformity undergoing surgical treatment. The clinical impact of this is uncertain. This study aimed to quantify the differences in pa ... Full text Open Access Link to item Cite

Defining Spino-Pelvic Alignment Thresholds: Should Operative Goals in Adult Spinal Deformity Surgery Account for Age?

Journal Article Spine (Phila Pa 1976) · January 2016 STUDY DESIGN: Retrospective review of prospective, multicenter database. OBJECTIVE: The aim of the study was to determine age-specific spino-pelvic parameters, to extrapolate age-specific Oswestry Disability Index (ODI) values from published Short Form (SF ... Full text Open Access Link to item Cite

Does Minimally Invasive Percutaneous Posterior Instrumentation Reduce Risk of Proximal Junctional Kyphosis in Adult Spinal Deformity Surgery? A Propensity-Matched Cohort Analysis.

Journal Article Neurosurgery · January 2016 BACKGROUND: Proximal junctional kyphosis (PJK) is a known complication after spinal deformity surgery. One potential cause is disruption of posterior muscular tension band during pedicle screw placement. OBJECTIVE: To investigate the effect of minimally in ... Full text Open Access Link to item Cite

Anatomy and Physiology of Congenital Spinal Lesions

Chapter · January 1, 2016 Full text Cite

Differential Diagnosis of Surgical Disorders of the Spine

Chapter · January 1, 2016 Full text Cite

Pediatric Spinal Deformities and Deformity Correction

Chapter · January 1, 2016 Full text Cite

Adult Thoracic and Lumbar Deformity

Chapter · January 1, 2016 Full text Cite

Posterior and Transforaminal Lumbar Interbody Fusion

Chapter · January 1, 2016 Full text Cite

Reliability assessment of a novel cervical spine deformity classification system.

Journal Article J Neurosurg Spine · December 2015 OBJECT: Despite the complexity of cervical spine deformity (CSD) and its significant impact on patient quality of life, there exists no comprehensive classification system. The objective of this study was to develop a novel classification system based on a ... Full text Open Access Link to item Cite

Impact of dynamic alignment, motion, and center of rotation on myelopathy grade and regional disability in cervical spondylotic myelopathy.

Journal Article J Neurosurg Spine · December 2015 OBJECT: Cervical stenosis is a defining feature of cervical spondylotic myelopathy (CSM). Matsunaga et al. proposed that elements of stenosis are both static and dynamic, where the dynamic elements magnify the canal deformation of the static state. For the ... Full text Open Access Link to item Cite

Novel Method Using Baseline Normalization and Area Under the Curve to Evaluate Differences in Outcome Between Treatment Groups and Application to Patients With Cervical Spondylotic Myelopathy Undergoing Anterior Versus Posterior Surgery.

Journal Article Spine (Phila Pa 1976) · December 2015 STUDY DESIGN: Retrospective review of a prospective database. OBJECTIVE: To describe a novel method that uses baseline normalization and area under the curve (AUC) to compare surgical outcomes between patients surgically treated anteriorly versus posterior ... Full text Open Access Link to item Cite

Anaplastic extramedullary cervical ependymoma with leptomeningeal metastasis.

Journal Article J Clin Neurosci · December 2015 We present a rare extramedullary ependymoma with diffuse spinal metastatic disease, and review the previous reports of extramedullary spinal ependymomas. Ependymomas are the most common intramedullary spinal cord tumor in adults. These tumors rarely presen ... Full text Open Access Link to item Cite

A Comprehensive Review of Complication Rates After Surgery for Adult Deformity: A Reference for Informed Consent.

Journal Article Spine Deform · November 2015 OBJECTIVE: An up-to-date review of recent literatures and a comprehensive reference for informed consent specific to ASD complications is lacking. The goal of the present study was to determine current complication rates after ASD surgery, in order to prov ... Full text Open Access Link to item Cite

Assessment of impact of standing long-cassette radiographs on surgical planning for lumbar pathology: An international survey of spine surgeons

Journal Article Journal of Neurosurgery: Spine · November 1, 2015 OBJECT: The associations among global spinal alignment, patient-reported disability, and surgical outcomes have increasingly gained attention. The assessment of global spinal alignment requires standing long-cassette anteroposterior and lateral radiographs ... Full text Open Access Cite

Impact of obesity on complications, infection, and patient-reported outcomes in adult spinal deformity surgery

Journal Article Journal of Neurosurgery: Spine · November 1, 2015 OBJECT: Adult spinal deformity (ASD) surgery is known for its high complication rate. This study examined the impact of obesity on complication rates, infection, and patient-reported outcomes in patients undergoing surgery for ASD. METHODS: This study was ... Full text Open Access Cite

Pedicle Subtraction Osteotomy in the Revision Versus Primary Adult Spinal Deformity Patient: Is There a Difference in Correction and Complications?

Journal Article Spine (Phila Pa 1976) · November 2015 STUDY DESIGN: Multicenter, prospective study of consecutive adult spinal deformity (ASD) patients. OBJECTIVE: To compare alignment correction and perioperative complications after pedicle subtraction osteotomies (PSO) in the primary versus revision surgery ... Full text Open Access Link to item Cite

Functional Limitations Due to Lumbar Stiffness in Adults With and Without Spinal Deformity.

Journal Article Spine (Phila Pa 1976) · October 15, 2015 STUDY DESIGN: Cross-sectional analysis. OBJECTIVE: To compare Lumbar Stiffness Disability Index (LSDI) scores between asymptomatic adults and patients with spinal deformity. SUMMARY OF BACKGROUND DATA: The LSDI was designed and validated as a tool to asses ... Full text Open Access Link to item Cite

Predictive value of 3-month lumbar discectomy outcomes in the NeuroPoint-SD Registry.

Journal Article J Neurosurg Spine · October 2015 OBJECT: The authors have established a multicenter registry to assess the efficacy and costs of common lumbar spinal procedures using prospectively collected outcomes. Collection of these data requires an extensive commitment of resources from each site. T ... Full text Open Access Link to item Cite

Postoperative Recovery After Adult Spinal Deformity Surgery: Comparative Analysis of Age in 149 Patients During 2-year Follow-up.

Journal Article Spine (Phila Pa 1976) · October 1, 2015 STUDY DESIGN: Retrospective review of a multicenter, prospective adult spinal deformity (ASD) database. OBJECTIVE: We hypothesized that increased age and increased preoperative disability would negatively impact both the length of time needed to achieve ma ... Full text Open Access Link to item Cite

Impact of Movement Disorders on Management of Spinal Deformity in the Elderly.

Journal Article Neurosurgery · October 2015 Spinal deformities are frequent and disabling complications of movement disorders such as Parkinson disease and multiple system atrophy. The most distinct spinal deformities include camptocormia, antecollis, Pisa syndrome, and scoliosis. Spinal surgery has ... Full text Open Access Link to item Cite

Progressive Spinal Kyphosis in the Aging Population.

Journal Article Neurosurgery · October 2015 Thoracic kyphosis tends to increase with age. Hyperkyphosis is defined as excessive curvature of the thoracic spine and may be associated with adverse health effects. Hyperkyphosis in isolation or as a component of degenerative kyphoscoliosis has important ... Full text Open Access Link to item Cite

Degenerative Spinal Deformity.

Journal Article Neurosurgery · October 2015 Degenerative spinal deformity afflicts a significant portion of the elderly and is increasing in prevalence. Recent evidence has revealed sagittal plane malalignment to be a key driver of pain and disability in this population and has led to a significant ... Full text Open Access Link to item Cite

Radiographical and Implant-Related Complications in Adult Spinal Deformity Surgery: Incidence, Patient Risk Factors, and Impact on Health-Related Quality of Life.

Journal Article Spine (Phila Pa 1976) · September 15, 2015 STUDY DESIGN: A multicenter, prospective review of surgical patients with adult spine deformity. OBJECTIVE: Assessment of the incidence, risk factor, and impact of radiographical and implant-related complications (RIC) on health-related quality of life mea ... Full text Open Access Link to item Cite

The likelihood of reaching minimum clinically important difference and substantial clinical benefit at 2 years following a 3-column osteotomy: analysis of 140 patients.

Journal Article J Neurosurg Spine · September 2015 OBJECT: Three-column osteotomies (3COs) are technically challenging techniques for correcting severe rigid spinal deformities. The impact of these interventions on outcomes reaching minimum clinically important difference (MCID) or substantial clinical ben ... Full text Open Access Link to item Cite

Comparison of best versus worst clinical outcomes for adult spinal deformity surgery: a retrospective review of a prospectively collected, multicenter database with 2-year follow-up.

Journal Article J Neurosurg Spine · September 2015 OBJECT: Although recent studies suggest that average clinical outcomes are improved following surgery for selected adult spinal deformity (ASD) patients, these outcomes span a broad range. Few studies have specifically addressed factors that may predict fa ... Full text Open Access Link to item Cite

Which daily functions are most affected by stiffness following total lumbar fusion: comparison of upper thoracic and thoracolumbar proximal endpoints.

Journal Article Spine (Phila Pa 1976) · September 1, 2015 STUDY DESIGN: Retrospective review of a multicenter, prospective adult spinal deformity (ASD) database. OBJECTIVE: The objective was to evaluate the impact of stiffness on activities of daily living (ADL) after instrumented total lumbar fusions to the pelv ... Full text Open Access Link to item Cite

How the neck affects the back: changes in regional cervical sagittal alignment correlate to HRQOL improvement in adult thoracolumbar deformity patients at 2-year follow-up.

Journal Article J Neurosurg Spine · August 2015 OBJECT Regional cervical sagittal alignment (C2-7 sagittal vertical axis [SVA]) has been shown to correlate with health-related quality of life (HRQOL). The study objective was to examine the relationship between cervical and thoracolumbar alignment parame ... Full text Open Access Link to item Cite

Rotational thromboelastometry-guided blood product management in major spine surgery.

Journal Article J Neurosurg Spine · August 2015 OBJECT Major spinal surgery in adult patients is often associated with significant intraoperative blood loss. Rotational thromboelastometry (ROTEM) is a functional viscoelastometric method for real-time hemostasis testing. In this study, the authors sought ... Full text Open Access Link to item Cite

Magnitude of preoperative cervical lordotic compensation and C2-T3 angle are correlated to increased risk of postoperative sagittal spinal pelvic malalignment in adult thoracolumbar deformity patients at 2-year follow-up.

Journal Article Spine J · August 1, 2015 BACKGROUND CONTEXT: Cervical deformity (CD) is prevalent among patients with adult spinal deformity (ASD). The effect of baseline cervical alignment on achieving optimal thoracolumbar alignment in ASD surgery is unclear. PURPOSE: This study assesses the re ... Full text Open Access Link to item Cite

Improvement in Pain, Disability, and Quality of Life following Lumbar Spine Surgery: A Predictive Model from the N2QOD Registry

Conference JOURNAL OF NEUROSURGERY · August 1, 2015 Link to item Cite

Spinal Pelvic Radiographic Thresholds for Regional Lumbar Disability are Age Dependent: Analysis of Multicenter Database

Conference JOURNAL OF NEUROSURGERY · August 1, 2015 Link to item Cite

How to Predict Return to Work After Lumbar Discectomy: Answers from the NeuroPoint-SD Registry

Conference JOURNAL OF NEUROSURGERY · August 1, 2015 Link to item Cite

Adult Spinal Deformity Patients Recall Fewer Than 50% of the Risks Discussed in the Informed Consent Process Preoperatively and the Recall Rate Worsens Significantly in the Postoperative Period.

Journal Article Spine (Phila Pa 1976) · July 15, 2015 STUDY DESIGN: Recall of the informed consent process in patients undergoing adult spinal deformity surgery and their family members was investigated prospectively. OBJECTIVE: To quantify the percentage recall of the most common complications discussed duri ... Full text Open Access Link to item Cite

Spine surgery training: Is it time to consider categorical spine surgery residency?

Journal Article Spine Journal · July 1, 2015 Full text Open Access Cite

Cervical compensatory alignment changes following correction of adult thoracic deformity: a multicenter experience in 57 patients with a 2-year follow-up.

Journal Article J Neurosurg Spine · June 2015 OBJECT Alignment changes in the cervical spine that occur following surgical correction for thoracic deformity remain poorly understood. The purpose of this study was to evaluate such changes in a cohort of adults with thoracic deformity treated surgically ... Full text Open Access Link to item Cite

The National Neurosurgery Quality and Outcomes Database (N2QOD): Predictors of Persistent 12 month Disability Following Lumbar Surgery

Conference JOURNAL OF NEUROSURGERY · June 1, 2015 Link to item Cite

Prevalence and Type of Cervical Deformity Among 470 Adults with Thoracolumbar Deformity

Conference JOURNAL OF NEUROSURGERY · June 1, 2015 Link to item Cite

Does Minimally Invasive Posterior Instrumentation (PPI) Prevent Proximal Junctional Kyphosis (PJK) in Adult Spinal Deformity (ASD) surgery? A Prospectively Acquired Propensity Matched Cohort Analysis

Conference JOURNAL OF NEUROSURGERY · June 1, 2015 Link to item Cite

Incremental Cost-Effectiveness of Adult Spinal Deformity Surgery: Observed QALYs with Surgery Compared to Predicted QALYs without Surgery

Conference JOURNAL OF NEUROSURGERY · June 1, 2015 Link to item Cite

Prospective, Multicenter Assessment of Acute Neurologic Complications following Complex Adult Spinal Deformity Surgery: The Scoli-RISK-1 Study

Conference JOURNAL OF NEUROSURGERY · June 1, 2015 Link to item Cite

Comprehensive study of back and leg pain improvements after adult spinal deformity surgery: analysis of 421 patients with 2-year follow-up and of the impact of the surgery on treatment satisfaction.

Journal Article J Neurosurg Spine · May 2015 OBJECT Back and leg pain are the primary outcomes of adult spinal deformity (ASD) and predict patients' seeking of surgical management. The authors sought to characterize changes in back and leg pain after operative or nonoperative management of ASD. Outco ... Full text Open Access Link to item Cite

Preoperative Cervical Hyperlordosis and C2–T3 Angle are Correlated to Increased Risk of Post-Op Sagittal Spinal Pelvic Malalignment in Adult Spinal Deformity Patients at 2-Year Follow-Up

Journal Article Global Spine Journal · May 1, 2015 Full text Open Access Cite

Outcomes of Operative and Nonoperative Treatment for Adult Spinal Deformity (ASD): A Prospective, Multicenter Matched and Unmatched Cohort Assessment with Minimum 2-Year Follow-Up

Journal Article Global Spine Journal · May 1, 2015 Introduction Adults with spinal deformity typically present with pain and disability. Aim Our objective was to compare outcomes for operative (op) and nonoperative (nonop) treatment for ASD based on a prospective, multicenter patient population. Material a ... Full text Open Access Cite

Clinical Impact Correlation of a Delphi-Based Proximal Junctional Kyphosis Severity Scale and HRQOL

Journal Article Global Spine Journal · May 1, 2015 Introduction Proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) are adverse outcomes following adult spinal surgery (ASD) surgery. There is a lack of consensus regarding which patients (pts) require revision surgery. The Hart ISSG PJK ... Full text Open Access Cite

Area under the Curve: Analysis of Approach-Related Recovery Time in 165 Operative Cervical Spondylotic Myelopathy Patients with a 2-Year Follow-Up

Journal Article Global Spine Journal · May 1, 2015 Full text Open Access Cite

Comparison of Best versus Worst Clinical Outcomes for Adult Spinal Deformity Surgery: A Prospective, Multicenter Assessment with Minimum 2-Year Follow-Up

Journal Article Global Spine Journal · May 1, 2015 Introduction Adults with spinal deformity typically present with pain and disability. Our objective was to compare outcomes for op and nonop treatment for ASD based on a prospective, multicenter patient population. Patients and Methods This is a multicente ... Full text Open Access Cite

Comparison of two minimally invasive surgery strategies to treat adult spinal deformity.

Journal Article J Neurosurg Spine · April 2015 OBJECT: Minimally invasive surgery (MIS) techniques are becoming a more common means of treating adult spinal deformity (ASD). The aim of this study was to compare the hybrid (HYB) surgical approach, involving minimally invasive lateral interbody fusion wi ... Full text Open Access Link to item Cite

The impact of standing regional cervical sagittal alignment on outcomes in posterior cervical fusion surgery.

Journal Article Neurosurgery · March 2015 BACKGROUND: Positive spinal regional and global sagittal malalignment has been repeatedly shown to correlate with pain and disability in thoracolumbar fusion. OBJECTIVE: To evaluate the relationship between regional cervical sagittal alignment and postoper ... Full text Open Access Link to item Cite

The comprehensive anatomical spinal osteotomy classification.

Journal Article Neurosurgery · March 2015 BACKGROUND: Global sagittal malalignment is significantly correlated with health-related quality-of-life scores in the setting of spinal deformity. In order to address rigid deformity patterns, the use of spinal osteotomies has seen a substantial increase. ... Full text Open Access Link to item Cite

Postoperative cervical deformity in 215 thoracolumbar patients with adult spinal deformity: prevalence, risk factors, and impact on patient-reported outcome and satisfaction at 2-year follow-up.

Journal Article Spine (Phila Pa 1976) · March 1, 2015 STUDY DESIGN: Retrospective review of prospective multicenter database. OBJECTIVE: Quantify the incidence of new onset cervical deformity (CD) after adult spinal deformity surgery of the thoracolumbar spine, identify predictors of development, and determin ... Full text Open Access Link to item Cite

Time to development, clinical and radiographic characteristics, and management of proximal junctional kyphosis following adult thoracolumbar instrumented fusion for spinal deformity.

Journal Article J Spinal Disord Tech · March 2015 STUDY DESIGN: A retrospective review. OBJECTIVE: To study time to development, clinical and radiographic characteristics, and management of proximal junctional kyphosis (PJK) following thoracolumbar instrumented fusion for adult spinal deformity (ASD). SUM ... Full text Open Access Link to item Cite

Maintenance of radiographic correction at 2 years following lumbar pedicle subtraction osteotomy is superior with upper thoracic compared with thoracolumbar junction upper instrumented vertebra.

Journal Article Eur Spine J · January 2015 PURPOSE: The goal of this study was to characterize the spino-pelvic realignment and the maintenance of that realignment by the upper-most instrumented vertebra (UIV) for adult deformity spinal (ASD) patients treated with lumbar pedicle subtraction osteoto ... Full text Open Access Link to item Cite

Evaluation of monoenergetic imaging to reduce metallic instrumentation artifacts in computed tomography of the cervical spine.

Journal Article J Neurosurg Spine · January 2015 OBJECT: Monoenergetic imaging with dual-energy CT has been proposed to reduce metallic artifacts in comparison with conventional polychromatic CT. The purpose of this study is to systematically evaluate and define the optimal dual-energy CT imaging paramet ... Full text Open Access Link to item Cite

Coronal plane spinal malalignment and Parkinson's disease: prevalence and associations with disease severity.

Journal Article Spine J · January 1, 2015 BACKGROUND CONTEXT: Parkinson's disease (PD) is a progressive degenerative disorder of the central nervous system. Patients with PD often present with abnormal posturing. PURPOSE: To investigate coronal plane deformities in patients with PD, and to evaluat ... Full text Open Access Link to item Cite

Comparison of Outcomes between Anterior and Posterior Cervical Procedures: Results of Surgery Involving Four or More Vertebral Levels from the AOSpine North America Cervical Spondylotic Myelopathy Study

Journal Article Global Spine Journal · January 1, 2015 Full text Open Access Cite

Prospective multicenter assessment of risk factors for rod fracture following surgery for adult spinal deformity.

Journal Article J Neurosurg Spine · December 2014 OBJECT: Improved understanding of rod fracture (RF) following adult spinal deformity (ASD) surgery could prove valuable for surgical planning, patient counseling, and implant design. The objective of this study was to prospectively assess the rates of and ... Full text Open Access Link to item Cite

The use of allograft and recombinant human bone morphogenetic protein for instrumented atlantoaxial fusions.

Journal Article World Neurosurg · December 2014 BACKGROUND: Iliac crest autograft is the historic gold standard for bone grafting, but is associated with a significant patient morbidity. Fusion rates of C1-C2 up to 88.9% using allograft and 96.7% using autologous iliac crest bone graft can be achieved w ... Full text Open Access Link to item Cite

Optimal surgical care for adolescent idiopathic scoliosis: an international consensus.

Journal Article Eur Spine J · December 2014 PURPOSE: The surgical management of adolescent idiopathic scoliosis (AIS) has seen many developments in the last two decades. Little high-level evidence is available to support these changes and guide treatment. This study aimed to identify optimal operati ... Full text Open Access Link to item Cite

Operative and nonoperative treatment approaches for lumbar degenerative disc disease have similar long-term clinical outcomes among patients with positive discography.

Journal Article World Neurosurg · November 2014 OBJECTIVE: It remains unclear whether fusion for lumbar degenerative disc disease with positive discography produces better outcomes compared with nonoperative treatment. The aim of this study was to compare outcomes of patients with discography-concordant ... Full text Open Access Link to item Cite

The National Neurosurgery Quality and Outcomes Database (N2QOD): a collaborative North American outcomes registry to advance value-based spine care.

Journal Article Spine (Phila Pa 1976) · October 15, 2014 STUDY DESIGN: National Prospective Observational Registry. OBJECTIVE: Describe our preliminary experience with the National Neurosurgery Quality and Outcomes Database (NQOD), a national collaborative registry of quality and outcomes reporting after low bac ... Full text Open Access Link to item Cite

Total hospital costs of surgical treatment for adult spinal deformity: an extended follow-up study.

Journal Article Spine J · October 1, 2014 BACKGROUND CONTEXT: Whereas the costs of primary surgery, revisions, and selected complications for adult spinal deformity (ASD) have been individually reported in the literature, the total costs over several years after surgery have not been assessed. The ... Full text Open Access Link to item Cite

Results of the AANS membership survey of adult spinal deformity knowledge: impact of training, practice experience, and assessment of potential areas for improved education: Clinical article.

Journal Article J Neurosurg Spine · October 2014 OBJECT: Adult spinal deformity (ASD) surgery is increasing in the spinal neurosurgeon's practice. METHODS: A survey of neurosurgeon AANS membership assessed the deformity knowledge base and impact of current training, education, and practice experience to ... Full text Open Access Link to item Cite

Dynamic stabilization.

Journal Article J Neurosurg Spine · October 2014 Full text Open Access Link to item Cite

TheT1 pelvic angle, a novel radiographic measure of global sagittal deformity, accounts for both spinal inclination and pelvic tilt and correlates with health-related quality of life.

Journal Article J Bone Joint Surg Am · October 1, 2014 BACKGROUND: Adult spinal deformity is a prevalent cause of pain and disability. Established measures of sagittal spinopelvic alignment such as sagittal vertical axis and pelvic tilt can be modified by postural compensation, including pelvic retroversion, k ... Full text Open Access Link to item Cite

Anterior versus posterior spinal correction and fusion for adolescent idiopathic scoliosis

Journal Article Cochrane Database of Systematic Reviews · September 29, 2014 This is the protocol for a review and there is no abstract. The objectives are as follows: To examine which intervention (anterior or posterior spinal correction and fusion) has the best functional clinical outcome (in terms of pain, participant satisfacti ... Full text Open Access Cite

Surgical treatment of pathological loss of lumbar lordosis (flatback) in patients with normal sagittal vertical axis achieves similar clinical improvement as surgical treatment of elevated sagittal vertical axis: clinical article.

Journal Article J Neurosurg Spine · August 2014 OBJECT: Increased sagittal vertical axis (SVA) correlates strongly with pain and disability for adults with spinal deformity. A subset of patients with sagittal spinopelvic malalignment (SSM) have flatback deformity (pelvic incidence-lumbar lordosis [PI-LL ... Full text Open Access Link to item Cite

Patients with adult spinal deformity treated operatively report greater baseline pain and disability than patients treated nonoperatively; however, deformities differ between age groups.

Journal Article Spine (Phila Pa 1976) · August 1, 2014 STUDY DESIGN: Multicenter, prospective analysis of consecutive patients with adult spinal deformity (ASD). OBJECTIVE: Identify age-related radiographical parameters associated with poor health-related quality of life (HRQOL) and treatment preferences for A ... Full text Open Access Link to item Cite

Prevalence and type of cervical deformity among 470 adults with thoracolumbar deformity.

Journal Article Spine (Phila Pa 1976) · August 1, 2014 STUDY DESIGN: Multicenter, prospective, consecutive case series. OBJECTIVE: To assess prevalence and type of cervical deformity among adults with thoracolumbar (TL) deformity and to assess for associations between cervical deformities and different types o ... Full text Open Access Link to item Cite

Depression and outcome.

Journal Article J Neurosurg Spine · August 2014 Full text Open Access Link to item Cite

Medical management.

Journal Article J Neurosurg Spine · August 2014 Full text Open Access Link to item Cite

In response.

Journal Article Spine (Phila Pa 1976) · July 1, 2014 Full text Open Access Link to item Cite

Sagittal spinopelvic malalignment in Parkinson disease: prevalence and associations with disease severity.

Journal Article Spine (Phila Pa 1976) · June 15, 2014 STUDY DESIGN: Prospective study. OBJECTIVE: Our objectives were to evaluate the prevalence of sagittal spinopelvic malalignment in a consecutive series of patients with Parkinson disease (PD) and to identify factors associated with sagittal spinopelvic def ... Full text Open Access Link to item Cite

Cost-effectiveness of lumbar discectomy and single-level fusion for spondylolisthesis: experience with the NeuroPoint-SD registry.

Journal Article Neurosurg Focus · June 2014 OBJECT: There is significant practice variation and uncertainty as to the value of surgical treatments for lumbar spine disorders. The authors' aim was to establish a multicenter registry to assess the efficacy and costs of common lumbar spinal procedures ... Full text Open Access Link to item Cite

Upper thoracic versus lower thoracic upper instrumented vertebrae endpoints have similar outcomes and complications in adult scoliosis.

Journal Article Spine (Phila Pa 1976) · June 1, 2014 STUDY DESIGN: Retrospective review-multicenter database. OBJECTIVE: The purpose of this study was to compare the upper thoracic (UT) and lower thoracic (LT) upper instrumented vertebrae (UIV) in long fusions to the sacrum for adult scoliosis. SUMMARY OF BA ... Full text Open Access Link to item Cite

The minimally invasive spinal deformity surgery algorithm: a reproducible rational framework for decision making in minimally invasive spinal deformity surgery.

Journal Article Neurosurg Focus · May 2014 OBJECT: Minimally invasive surgery (MIS) is an alternative to open deformity surgery for the treatment of patients with adult spinal deformity. However, at this time MIS techniques are not as versatile as open deformity techniques, and MIS techniques have ... Full text Open Access Link to item Cite

Less invasive surgery for treating adult spinal deformities: ceiling effects for deformity correction with 3 different techniques.

Journal Article Neurosurg Focus · May 2014 OBJECT: Minimally invasive surgery (MIS) options for the treatment of adult spinal deformity (ASD) have advanced significantly over the past decade. However, a wide array of options have been described as being MIS or less invasive. In this study the autho ... Full text Open Access Link to item Cite

Evaluation of complications and neurological deficits with three-column spine reconstructions for complex spinal deformity: a retrospective Scoli-RISK-1 study.

Journal Article Neurosurg Focus · May 2014 OBJECT: The goal in this study was to evaluate the risk factors for complications, including new neurological deficits, in the largest cohort of patients with adult spinal deformity to date. METHODS: The Scoli-RISK-1 inclusion criteria were used to identif ... Full text Open Access Link to item Cite

Complications and intercenter variability of three-column osteotomies for spinal deformity surgery: a retrospective review of 423 patients.

Journal Article Neurosurg Focus · May 2014 OBJECT: Three-column resection osteotomies (3COs) are commonly performed for sagittal deformity but have high rates of reported complications. Authors of this study aimed to examine the incidence of and intercenter variability in major intraoperative compl ... Full text Open Access Link to item Cite

Complications in adult spinal deformity surgery: an analysis of minimally invasive, hybrid, and open surgical techniques.

Journal Article Neurosurg Focus · May 2014 OBJECT: It is hypothesized that minimally invasive surgical techniques lead to fewer complications than open surgery for adult spinal deformity (ASD). The goal of this study was to analyze matched patient cohorts in an attempt to isolate the impact of appr ... Full text Open Access Link to item Cite

Editorial: Incremental cost-effectiveness of adult spinal deformity surgery.

Journal Article Neurosurg Focus · May 2014 Full text Open Access Link to item Cite

Introduction: Adult spinal deformity: pathophysiology and corrective measures.

Journal Article Neurosurg Focus · May 2014 Full text Open Access Link to item Cite

Comparison of radiographic results after minimally invasive, hybrid, and open surgery for adult spinal deformity: a multicenter study of 184 patients.

Journal Article Neurosurg Focus · May 2014 OBJECT: Various surgical approaches, including open, minimally invasive, and hybrid techniques, have gained momentum in the management of adult spinal deformity. However, few data exist on the radiographic outcomes of different surgical techniques. The obj ... Full text Open Access Link to item Cite

Lateral mass screw fixation in the cervical spine.

Journal Article J Neurosurg Spine · May 2014 Full text Open Access Link to item Cite

Nonoperative care to manage the sacroiliac joint.

Journal Article J Neurosurg Spine · April 2014 Full text Open Access Link to item Cite

Defining rates and causes of mortality associated with spine surgery: comparison of 2 data collection approaches through the Scoliosis Research Society.

Journal Article Spine (Phila Pa 1976) · April 1, 2014 STUDY DESIGN: Retrospective review of prospectively collected databases. OBJECTIVE: To compare 2 approaches for assessment of mortality associated with spine surgery. SUMMARY OF BACKGROUND DATA: The Scoliosis Research Society collects morbidity and mortali ... Full text Open Access Link to item Cite

Reciprocal changes in cervical spine alignment after corrective thoracolumbar deformity surgery.

Journal Article Eur Spine J · March 2014 PURPOSE: To identify changes in cervical alignment parameters following surgical correction of thoracolumbar deformity and then assess the preoperative parameters which induce changes in cervical alignment following corrective thoracolumbar deformity surge ... Full text Open Access Link to item Cite

Impact of age on the likelihood of reaching a minimum clinically important difference in 374 three-column spinal osteotomies: clinical article.

Journal Article J Neurosurg Spine · March 2014 OBJECT: Spinal osteotomies for adult spinal deformity correction may include resection of all 3 spinal columns (pedicle subtraction osteotomy [PSO] and vertebral column resection [VCR]). The relationship between patient age and health-related quality of li ... Full text Open Access Link to item Cite

Does recombinant human bone morphogenetic protein-2 use in adult spinal deformity increase complications and are complications associated with location of rhBMP-2 use? A prospective, multicenter study of 279 consecutive patients.

Journal Article Spine (Phila Pa 1976) · February 1, 2014 STUDY DESIGN: Multicenter, prospective analysis of consecutive patients with adult spinal deformity (ASD). OBJECTIVE: Evaluate complications associated with recombinant human bone morphogenetic protein-2 (rhBMP-2) use in ASD. SUMMARY OF BACKGROUND DATA: Of ... Full text Open Access Link to item Cite

A prospective, multicenter, phase I matched-comparison group trial of safety, pharmacokinetics, and preliminary efficacy of riluzole in patients with traumatic spinal cord injury.

Journal Article J Neurotrauma · February 1, 2014 A prospective, multicenter phase I trial was undertaken by the North American Clinical Trials Network (NACTN) to investigate the pharmacokinetics and safety of, as well as obtain pilot data on, the effects of riluzole on neurological outcome in acute spina ... Full text Open Access Link to item Cite

Lumbopelvic Parameters

Chapter · January 1, 2014 The demographic shift toward an older population in the United States has led to an increased prevalence of adult scoliosis, with reported rates as high as 70 % among the elderly [1]. Although the disease may have a relatively benign course, some patients ... Full text Cite

The comprehensive anatomical spinal osteotomy classification.

Journal Article Neurosurgery · January 2014 BACKGROUND: Global sagittal malalignment is significantly correlated with health-related quality-of-life scores in the setting of spinal deformity. In order to address rigid deformity patterns, the use of spinal osteotomies has seen a substantial increase. ... Full text Open Access Link to item Cite

Revision extension to the pelvis versus primary spinopelvic instrumentation in adult deformity: comparison of clinical outcomes and complications.

Journal Article World Neurosurg · 2014 OBJECTIVE: To evaluate the outcomes and complications of patients with adult spinal deformity treated in a primary versus revision fashion with long fusions to the sacropelvis. METHODS: A retrospective review was performed of a multicenter consecutive seri ... Full text Open Access Link to item Cite

Complications associated with surgical treatment of traumatic spinal fractures: a review of the scoliosis research society morbidity and mortality database.

Journal Article World Neurosurg · 2014 OBJECTIVE: Traumatic spinal fracture is a common indication for surgery, with an associated high incidence of perioperative complications. The literature provides a wide range in the incidence of complications. We seek to assess the perioperative morbidity ... Full text Open Access Link to item Cite

Radiographic outcomes of adult spinal deformity correction: A critical analysis of variability and failures across deformity patterns

Journal Article Spine Deformity · January 1, 2014 Study Design Multicenter, prospective, consecutive, surgical case series from the International Spine Study Group. Objectives To evaluate the effectiveness of surgical treatment in restoring spinopelvic (SP) alignment. Summary of Background Data Pain and d ... Full text Open Access Cite

Mild diabetes is not a contraindication for surgical decompression in cervical spondylotic myelopathy: results of the AOSpine North America multicenter prospective study (CSM).

Journal Article Spine J · January 2014 BACKGROUND CONTEXT: Cervical spondylotic myelopathy (CSM) is a chronic spinal cord disease and can lead to progressive or stepwise neurologic decline. Several factors may influence this process, including extent of spinal cord compression, duration of symp ... Full text Open Access Link to item Cite

Anterior versus posterior surgical approaches to treat cervical spondylotic myelopathy: outcomes of the prospective multicenter AOSpine North America CSM study in 264 patients.

Journal Article Spine (Phila Pa 1976) · December 15, 2013 STUDY DESIGN: A prospective observational multicenter study. OBJECTIVE: To help solve the debate regarding whether the anterior or posterior surgical approach is optimal for patients with cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND DATA: T ... Full text Open Access Link to item Cite

Effect of type II odontoid fracture nonunion on outcome among elderly patients treated without surgery: based on the AOSpine North America geriatric odontoid fracture study.

Journal Article Spine (Phila Pa 1976) · December 15, 2013 STUDY DESIGN: Subgroup analysis of a prospective multicenter study. OBJECTIVE: Outcome analysis of nonoperatively treated elderly patients with type II odontoid fractures, including assessment of consequence of a fracture nonunion. SUMMARY OF BACKGROUND DA ... Full text Open Access Link to item Cite

Does smoking have an impact on fusion rate in single-level anterior cervical discectomy and fusion with allograft and rigid plate fixation? Clinical article.

Journal Article J Neurosurg Spine · November 2013 OBJECT: Although smoking has been shown to negatively affect fusion rates in patients undergoing multilevel fusions of the cervical and lumbar spine, the effect of smoking on fusion rates in patients undergoing single-level anterior cervical discectomy and ... Full text Open Access Link to item Cite

The efficacy of lumbar discectomy and single-level fusion for spondylolisthesis: results from the NeuroPoint-SD registry: clinical article.

Journal Article J Neurosurg Spine · November 2013 OBJECT: There is significant practice variation and considerable uncertainty among payers and other major stakeholders as to whether many surgical treatments are effective in actual US spine practice. The aim of this study was to establish a multicenter co ... Full text Open Access Link to item Cite

Association of myelopathy scores with cervical sagittal balance and normalized spinal cord volume: analysis of 56 preoperative cases from the AOSpine North America Myelopathy study.

Journal Article Spine (Phila Pa 1976) · October 15, 2013 STUDY DESIGN: Post hoc analysis of prospectively collected data. OBJECTIVE: Development of methods to determine in vivo spinal cord dimensions and application to correlate preoperative alignment, myelopathy, and health-related quality-of-life scores in pat ... Full text Open Access Link to item Cite

Frequency, timing, and predictors of neurological dysfunction in the nonmyelopathic patient with cervical spinal cord compression, canal stenosis, and/or ossification of the posterior longitudinal ligament.

Journal Article Spine (Phila Pa 1976) · October 15, 2013 STUDY DESIGN: Systematic review and survey. OBJECTIVE: To perform an evidence synthesis of the literature and obtain information from the global spine care community assessing the frequency, timing, and predictors of symptom development in patients with ra ... Full text Open Access Link to item Cite

Predictive factors affecting outcome after cervical laminoplasty.

Journal Article Spine (Phila Pa 1976) · October 15, 2013 STUDY DESIGN: Systematic review. OBJECTIVE: To determine whether various preoperative factors affect patient outcome after cervical laminoplasty for cervical spondylotic myelopathy (CSM) and/or ossification of posterior longitudinal ligament (OPLL). SUMMAR ... Full text Open Access Link to item Cite

Outcomes after laminoplasty compared with laminectomy and fusion in patients with cervical myelopathy: a systematic review.

Journal Article Spine (Phila Pa 1976) · October 15, 2013 STUDY DESIGN: Systematic review. OBJECTIVE: To determine the effectiveness and safety of cervical laminoplasty versus laminectomy and fusion for the treatment of cervical myelopathy, and to identify any patient subgroups for whom one treatment may result i ... Full text Open Access Link to item Cite

Cervical radiographical alignment: comprehensive assessment techniques and potential importance in cervical myelopathy.

Journal Article Spine (Phila Pa 1976) · October 15, 2013 STUDY DESIGN: Narrative review. OBJECTIVE: To provide a comprehensive narrative review of cervical alignment parameters, the methods for quantifying cervical alignment, normal cervical alignment values, and how alignment is associated with cervical deformi ... Full text Open Access Link to item Cite

Reoperation rates and impact on outcome in a large, prospective, multicenter, adult spinal deformity database: clinical article.

Journal Article J Neurosurg Spine · October 2013 OBJECT: Complications and reoperation for surgery to correct adult spinal deformity are not infrequent, and many studies have analyzed the rates and factors that influence the likelihood of reoperation. However, there is a need for more comprehensive analy ... Full text Open Access Link to item Cite

Failure of lumbopelvic fixation after long construct fusions in patients with adult spinal deformity: clinical and radiographic risk factors: clinical article.

Journal Article J Neurosurg Spine · October 2013 OBJECT: Lumbopelvic fixation provides biomechanical support to the base of the long constructs used for adult spinal deformity. However, the failure rate of the lumbopelvic fixation and its risk factors are not well known. The authors' objective was to rep ... Full text Open Access Link to item Cite

The SRS-Schwab adult spinal deformity classification: assessment and clinical correlations based on a prospective operative and nonoperative cohort.

Journal Article Neurosurgery · October 2013 BACKGROUND: The SRS-Schwab classification of adult spinal deformity (ASD) is a validated system that provides a common language for the complex pathology of ASD. Classification reliability has been reported; however, correlation with treatment has not been ... Full text Open Access Link to item Cite

Efficacy and safety of surgical decompression in patients with cervical spondylotic myelopathy: results of the AOSpine North America prospective multi-center study.

Journal Article J Bone Joint Surg Am · September 18, 2013 BACKGROUND: Cervical spondylotic myelopathy is the leading cause of spinal cord dysfunction worldwide. The objective of this study was to evaluate the impact of surgical decompression on functional, quality-of-life, and disability outcomes at one year afte ... Full text Open Access Link to item Cite

Identification of decision criteria for revision surgery among patients with proximal junctional failure after surgical treatment of spinal deformity.

Journal Article Spine (Phila Pa 1976) · September 1, 2013 STUDY DESIGN: Multicenter, retrospective, consecutive case series. OBJECTIVE: This study aims to identify demographic and radiographical characteristics that influence the decision to perform revision surgery among patients with proximal junctional failure ... Full text Open Access Link to item Cite

Change in classification grade by the SRS-Schwab Adult Spinal Deformity Classification predicts impact on health-related quality of life measures: prospective analysis of operative and nonoperative treatment.

Journal Article Spine (Phila Pa 1976) · September 1, 2013 STUDY DESIGN: Multicenter, prospective, consecutive series. OBJECTIVE: To evaluate responsiveness of the Scoliosis Research Society (SRS)-Schwab adult spinal deformity (ASD) classification to changes in health-related quality of life (HRQOL) after treatmen ... Full text Open Access Link to item Cite

Dysphagia following combined anterior-posterior cervical spine surgeries.

Journal Article J Neurosurg Spine · September 2013 OBJECT: This study was undertaken to evaluate the incidence of and risk factors associated with the development of dysphagia following same-day combined anterior-posterior cervical spine surgeries. METHODS: The records of 30 consecutive patients who underw ... Full text Open Access Link to item Cite

A standardized nomenclature for cervical spine soft-tissue release and osteotomy for deformity correction: clinical article.

Journal Article J Neurosurg Spine · September 2013 OBJECT: Cervical spine osteotomies are powerful techniques to correct rigid cervical spine deformity. Many variations exist, however, and there is no current standardized system with which to describe and classify cervical osteotomies. This complicates the ... Full text Open Access Link to item Cite

Cervical spine alignment, sagittal deformity, and clinical implications: a review.

Journal Article J Neurosurg Spine · August 2013 This paper is a narrative review of normal cervical alignment, methods for quantifying alignment, and how alignment is associated with cervical deformity, myelopathy, and adjacent-segment disease (ASD), with discussions of health-related quality of life (H ... Full text Open Access Link to item Cite

The National Neurosurgery Quality And Outcomes Database (N2QOD) Pilot: Patient-Centered Measurement Of Quality And Effectiveness Of Care

Conference JOURNAL OF NEUROSURGERY · August 1, 2013 Link to item Cite

Health Impact Comparison of Different Disease States And Population Norms To Adult Spinal Deformity (ASD): A Call For Medical Attention

Conference JOURNAL OF NEUROSURGERY · August 1, 2013 Link to item Cite

Likelihood Of Reaching Minimal Clinically Important Difference (MCID) In Health Related Quality Of Life (HRQOL) Measures: Prospective Analysis Of Operative And Non-operative Treatment Of Adult Spinal Deformity (ASD)

Conference JOURNAL OF NEUROSURGERY · August 1, 2013 Link to item Cite

Riluzole For The Treatment Of Spinal Cord Injury: A Phase 1 Trial And Future Directions

Conference JOURNAL OF NEUROSURGERY · August 1, 2013 Link to item Cite

Anterior Vs. Posterior Surgical Approaches To Treat Cervical Spondylotic Myelopathy: Outcomes Of The Prospective Multicenter AOSpine North America CSM Study In 278 Patients

Conference JOURNAL OF NEUROSURGERY · August 1, 2013 Link to item Cite

Stabilization of the sacroiliac joint.

Journal Article Neurosurg Focus · July 2013 Lower back pain and pain involving the area of the posterior iliac spine are extremely common. Degeneration of the sacroiliac joint (SIJ) is one potential cause for lower back pain and pain radiating into the groin or buttocks. Degenerative changes to the ... Full text Open Access Link to item Cite

Sexual function in older adults following thoracolumbar to pelvic instrumentation for spinal deformity.

Journal Article J Neurosurg Spine · July 2013 OBJECT: Sexual function is an often-overlooked aspect of health-related quality of life among older adults treated for spinal deformity. The authors' objective was to assess sexual function among older adults following thoracolumbar fusion with pelvic fixa ... Full text Open Access Link to item Cite

The AOSpine North America Geriatric Odontoid Fracture Mortality Study: a retrospective review of mortality outcomes for operative versus nonoperative treatment of 322 patients with long-term follow-up.

Journal Article Spine (Phila Pa 1976) · June 1, 2013 STUDY DESIGN: Retrospective, multicenter cohort study. OBJECTIVE: Assess for differences in short- and long-term mortality between operative and nonoperative treatment for elderly patients with type II odontoid fractures. SUMMARY OF BACKGROUND DATA: There ... Full text Open Access Link to item Cite

Radiographical spinopelvic parameters and disability in the setting of adult spinal deformity: a prospective multicenter analysis.

Journal Article Spine (Phila Pa 1976) · June 1, 2013 STUDY DESIGN: Prospective multicenter study evaluating operative (OP) versus nonoperative (NONOP) treatment for adult spinal deformity (ASD). OBJECTIVE: Evaluate correlations between spinopelvic parameters and health-related quality of life (HRQOL) scores ... Full text Open Access Link to item Cite

Incidence, mode, and location of acute proximal junctional failures after surgical treatment of adult spinal deformity.

Journal Article Spine (Phila Pa 1976) · May 20, 2013 STUDY DESIGN: Multicenter, retrospective series. OBJECTIVE: To analyze the incidence, mode, and location of acute proximal junctional failures (APJFs) after surgical treatment of adult spinal deformity. SUMMARY OF BACKGROUND DATA: Early proximal junctional ... Full text Open Access Link to item Cite

Dorsal thoracic arachnoid web and the "scalpel sign": a distinct clinical-radiologic entity.

Journal Article AJNR Am J Neuroradiol · May 2013 Arachnoid webs are intradural extramedullary bands of arachnoid tissue that can extend to the pial surface of the spinal cord, causing a focal dorsal indentation of the cord. These webs tend to occur in the upper thoracic spine and may produce a characteri ... Full text Open Access Link to item Cite

Comparison of patient and surgeon perceptions of adverse events after adult spinal deformity surgery.

Journal Article Spine (Phila Pa 1976) · April 20, 2013 STUDY DESIGN: Survey based on complication scenarios. OBJECTIVE: To assess and compare perceived potential impacts of various perioperative adverse events by both surgeons and patients. SUMMARY OF BACKGROUND DATA: Incidence of adverse events after adult sp ... Full text Open Access Link to item Cite

Functional and quality-of-life outcomes in geriatric patients with type-II dens fracture.

Journal Article J Bone Joint Surg Am · April 17, 2013 BACKGROUND: Dens fractures are relatively common in the elderly. The treatment of Type-II dens fractures remains controversial. The aim of this multicenter prospective cohort study was to compare outcomes (assessed with use of validated clinical measures) ... Full text Open Access Link to item Cite

Posterior global malalignment after osteotomy for sagittal plane deformity: it happens and here is why.

Journal Article Spine (Phila Pa 1976) · April 1, 2013 STUDY DESIGN: Multicenter, retrospective analysis of 183 consecutive patients undergoing lumbar osteotomy. OBJECTIVE: To evaluate cause and impact of posterior postoperative alignment. SUMMARY OF BACKGROUND DATA: Sagittal malalignment in the setting of adu ... Full text Open Access Link to item Cite

Classifications for adult spinal deformity and use of the Scoliosis Research Society-Schwab Adult Spinal Deformity Classification.

Journal Article Neurosurg Clin N Am · April 2013 Adult spinal deformity (ASD) is a complex disease state that pathologically alters standing upright posture and is associated with substantial pain and disability. This article provides an overview of classification systems for spinal deformity, clarifies ... Full text Open Access Link to item Cite

Management of high-grade spondylolisthesis.

Journal Article Neurosurg Clin N Am · April 2013 Management of high-grade spondylolisthesis (HGS) remains challenging and is associated with significant controversies. The best surgical procedure remains debatable. Although the need for instrumentation is generally agreed upon, significant controversies ... Full text Open Access Link to item Cite

Spinal deformity surgery.

Journal Article Neurosurg Clin N Am · April 2013 Full text Open Access Link to item Cite

Proximal junctional kyphosis and proximal junctional failure.

Journal Article Neurosurg Clin N Am · April 2013 Proximal junctional failure (PJF) should be distinguished from proximal junctional kyphosis, which is a recurrent deformity with limited clinical impact. PJF includes mechanical failure, and is a significant complication following adult spinal deformity su ... Full text Open Access Link to item Cite

Coronal realignment and reduction techniques and complication avoidance.

Journal Article Neurosurg Clin N Am · April 2013 Scoliosis is a broad term encompassing multiple pathologies with different etiologies. Patients may range from the infant with congenital deformity, to the adolescent with idiopathic scoliosis, to the elderly patient with severe degenerative scoliosis. Tre ... Full text Open Access Link to item Cite

Clinical and radiographic evaluation of the adult spinal deformity patient.

Journal Article Neurosurg Clin N Am · April 2013 Among the prevalent forms of adult spinal deformity are residual adolescent idiopathic and degenerative scoliosis, kyphotic deformity, and spondylolisthesis. Clinical evaluation should include a thorough history, discussion of concerns, and a review of com ... Full text Open Access Link to item Cite

Clinical and radiographic parameters that distinguish between the best and worst outcomes of scoliosis surgery for adults.

Journal Article Eur Spine J · February 2013 PURPOSE: Predictors of marked improvement versus failure to improve following surgery for adult scoliosis have not been identified. Our objective was to identify factors that distinguish between patients with the best and worst outcomes following surgery f ... Full text Open Access Link to item Cite

Editorial: Recombinant human bone morphogenetic protein-2.

Journal Article J Neurosurg Spine · February 2013 Full text Open Access Link to item Cite

The impact of facet dislocation on clinical outcomes after cervical spinal cord injury: results of a multicenter North American prospective cohort study.

Journal Article Spine (Phila Pa 1976) · January 15, 2013 STUDY DESIGN: A multicenter prospective cohort study. OBJECTIVE: To define differences in baseline characteristics and long-term clinical outcomes in patients with cervical spinal cord injury (SCI) with and without facet dislocation (FD). SUMMARY OF BACKGR ... Full text Open Access Link to item Cite

Multiple-day drainage when using bone morphogenic protein for long-segment thoracolumbar fusions is associated with low rates of wound complications.

Journal Article World Neurosurg · 2013 BACKGROUND: Concerns over increased wound complication rates have been raised when bone morphogenic protein (BMP) is used as an adjunct for fusion in spinal surgery. This study evaluated 87 consecutive patients undergoing long-segment thoracolumbar spinal ... Full text Open Access Link to item Cite

A survey-based study of wrong-level lumbar spine surgery: the scope of the problem and current practices in place to help avoid these errors.

Journal Article World Neurosurg · 2013 OBJECTIVE: To understand better the scope of wrong-level lumbar spine surgery and current practices in place to help avoid such errors. METHODS: The Joint Section on Disorders of the Spine and Peripheral Nerves (Spine Section) developed a survey on single- ... Full text Open Access Link to item Cite

Outcomes and complications of extension of previous long fusion to the sacro-pelvis: is an anterior approach necessary?

Journal Article World Neurosurg · January 2013 BACKGROUND: Patients with previous multilevel spinal fusion may require extension of the fusion to the sacro-pelvis. Our objective was to evaluate the outcomes and complications of these patients, stratified based on whether the revision was performed usin ... Full text Open Access Link to item Cite

Editorial: minimally invasive spinal deformity surgery.

Journal Article J Neurosurg Spine · January 2013 Full text Open Access Link to item Cite

High-Grade spondylolisthesis: Reduction and fusion versus in situ fusion

Chapter · December 1, 2012 Full text Cite

Risk factors for major peri-operative complications in adult spinal deformity surgery: a multi-center review of 953 consecutive patients.

Journal Article Eur Spine J · December 2012 PURPOSE: Major peri-operative complications for adult spinal deformity (ASD) surgery remain common. However, risk factors have not been clearly defined. Our objective was to identify patient and surgical parameters that correlate with the development of ma ... Full text Open Access Link to item Cite

Rates and causes of mortality associated with spine surgery based on 108,419 procedures: a review of the Scoliosis Research Society Morbidity and Mortality Database.

Journal Article Spine (Phila Pa 1976) · November 1, 2012 STUDY DESIGN: A retrospective review of a prospectively collected database. OBJECTIVE: To assess rates and causes of mortality associated with spine surgery. SUMMARY OF BACKGROUND DATA: Despite the best of care, all surgical procedures have inherent risks ... Full text Open Access Link to item Cite

Proximal junctional kyphosis as a distinct form of adjacent segment pathology after spinal deformity surgery: a systematic review.

Journal Article Spine (Phila Pa 1976) · October 15, 2012 STUDY DESIGN: Systematic review. OBJECTIVE: To review the literature on proximal junctional kyphosis (PJK) as a specific form for proximal adjacent segment pathology and report on the incidence, timing, risk factors, and effect on health-related quality of ... Full text Open Access Link to item Cite

Frequency, risk factors, and treatment of distal adjacent segment pathology after long thoracolumbar fusion: a systematic review.

Journal Article Spine (Phila Pa 1976) · October 15, 2012 STUDY DESIGN: Systematic review. OBJECTIVE: To systematically review the literature related to distal adjacent segment pathology (ASP) after long thoracolumbar fusions for deformity including frequency, risk factors, frequency differences between adolescen ... Full text Open Access Link to item Cite

Terminology.

Journal Article Spine (Phila Pa 1976) · October 15, 2012 Full text Open Access Link to item Cite

Spontaneous improvement of cervical alignment after correction of global sagittal balance following pedicle subtraction osteotomy.

Journal Article J Neurosurg Spine · October 2012 OBJECT: Sagittal spinopelvic malalignment is a significant cause of pain and disability in patients with adult spinal deformity. Surgical correction of spinopelvic malalignment can result in compensatory changes in spinal alignment outside of the fused spi ... Full text Open Access Link to item Cite

Assessment of symptomatic rod fracture after posterior instrumented fusion for adult spinal deformity.

Journal Article Neurosurgery · October 2012 BACKGROUND: Improved understanding of rod fracture (RF) in adult spinal deformity could be valuable for implant design, surgical planning, and patient counseling. OBJECTIVE: To evaluate symptomatic RF after posterior instrumented fusion for adult spinal de ... Full text Open Access Link to item Cite

The impact of standing regional cervical sagittal alignment on outcomes in posterior cervical fusion surgery.

Journal Article Neurosurgery · September 2012 BACKGROUND: Positive spinal regional and global sagittal malalignment has been repeatedly shown to correlate with pain and disability in thoracolumbar fusion. OBJECTIVE: To evaluate the relationship between regional cervical sagittal alignment and postoper ... Full text Open Access Link to item Cite

Predictors of pulmonary complications in blunt traumatic spinal cord injury.

Journal Article J Neurosurg Spine · September 2012 OBJECT: Pulmonary complications are the most common acute systemic adverse events following spinal cord injury (SCI), and contribute to morbidity, mortality, and increased length of hospital stay (LOS). Identification of factors associated with pulmonary c ... Full text Open Access Link to item Cite

Pharmacology of riluzole in acute spinal cord injury.

Journal Article J Neurosurg Spine · September 2012 OBJECT: The aim of this paper was to characterize individual and population pharmacokinetics of enterally administered riluzole in a Phase 1 clinical trial of riluzole as a neuroprotective agent in adults 18-70 years old with acute spinal cord injury (SCI) ... Full text Open Access Link to item Cite

Incidence and severity of acute complications after spinal cord injury.

Journal Article J Neurosurg Spine · September 2012 OBJECT: The aim of this multicenter, prospective study was to determine the spectrum, incidence, and severity of complications during the initial hospitalization of patients with spinal cord injury. METHODS: The study was conducted at 9 university-affiliat ... Full text Open Access Link to item Cite

Riluzole for the treatment of acute traumatic spinal cord injury: rationale for and design of the NACTN Phase I clinical trial.

Journal Article J Neurosurg Spine · September 2012 In the immediate period after traumatic spinal cord injury (SCI) a variety of secondary injury mechanisms combine to gradually expand the initial lesion size, potentially leading to diminished neurological outcomes at long-term follow-up. Riluzole, a benzo ... Full text Open Access Link to item Cite

A clinical prediction model for long-term functional outcome after traumatic spinal cord injury based on acute clinical and imaging factors.

Journal Article J Neurotrauma · September 2012 To improve clinicians' ability to predict outcome after spinal cord injury (SCI) and to help classify patients within clinical trials, we have created a novel prediction model relating acute clinical and imaging information to functional outcome at 1 year. ... Full text Open Access Link to item Cite

Outcomes, Expectations, and Complications Overview for the Surgical Treatment of Adult and Pediatric Spinal Deformity

Journal Article Spine Deformity · September 1, 2012 The aim of this article was to summarize current literature on surgical treatment of pediatric and adult spinal deformity with regard to clinical outcomes and surgical complications. When surgery is considered for treatment of spinal deformity, it is impor ... Full text Open Access Cite

Intraoperative Neurophysiological Monitoring in Spine Deformity Surgery

Journal Article Spine Deformity · September 1, 2012 Although the incidence of neurologic injury in deformity surgery is low, the repercussions are devastating; therefore, every measure available should be adopted to minimize that risk. Advances in instrumentation have been paralleled by the development and ... Full text Open Access Cite

Impact of magnitude and percentage of global sagittal plane correction on health-related quality of life at 2-years follow-up.

Journal Article Neurosurgery · August 2012 BACKGROUND: Sagittal plane malalignment has been established as the main radiographic driver of disability in adult spinal deformity (ASD). OBJECTIVE: To evaluate the amount of sagittal correction needed for a patient to perceive improvement (minimal clini ... Full text Open Access Link to item Cite

Does prior short-segment surgery for adult scoliosis impact perioperative complication rates and clinical outcome among patients undergoing scoliosis correction?

Journal Article J Neurosurg Spine · August 2012 OBJECT: In many adults with scoliosis, symptoms can be principally referable to focal pathology and can be addressed with short-segment procedures, such as decompression with or without fusion. A number of patients subsequently require more extensive scoli ... Full text Open Access Link to item Cite

The Efficacy of Lumbar Discectomy and Single Level Fusion for Spondylolisthesis: Neuropoint-SD Registry Initial Results

Conference JOURNAL OF NEUROSURGERY · August 1, 2012 Link to item Cite

Is Surgery for Cervical Spondylotic Myelopathy Cost-Effective?

Conference JOURNAL OF NEUROSURGERY · August 1, 2012 Link to item Cite

The Scope and Impact of Wrong-Level Lumbar Spine Surgery: A Survey of the Joint Section on Disorders of the Spine and Peripheral Nerves

Conference JOURNAL OF NEUROSURGERY · August 1, 2012 Link to item Cite

Functional and Quality of Life Outcomes in Geriatric Patients with Type II Odontoid Fracture: One Year Results from the AOSpine North America Multi-Center GOF Prospective Study

Conference JOURNAL OF NEUROSURGERY · August 1, 2012 Link to item Cite

A Prediction Model for Functional Outcome After Traumatic Spinal Cord Injury

Conference JOURNAL OF NEUROSURGERY · August 1, 2012 Link to item Cite

How the Assessment of Pelvic Tilt, Pelvic Incidence/Lumbar Lordosis Mismatch and Sagittal Vertical Axis Predicts Disability in Adult Spinal Deformity: A Prospective Analysis

Conference JOURNAL OF NEUROSURGERY · August 1, 2012 Link to item Cite

Short-term complications associated with surgery for high-grade spondylolisthesis in adults and pediatric patients: a report from the scoliosis research society morbidity and mortality database.

Journal Article Neurosurgery · July 2012 BACKGROUND: Although it is generally agreed upon that surgery for high-grade spondylolisthesis (HGS) is associated with more complications than low-grade spondylolisthesis, its description is primarily based on case reports and relatively small case series ... Full text Open Access Link to item Cite

Fehlings et al respond

Journal Article Spine Journal · June 1, 2012 Full text Open Access Cite

Sagittal realignment failures following pedicle subtraction osteotomy surgery: are we doing enough?: Clinical article.

Journal Article J Neurosurg Spine · June 2012 OBJECT: Pedicle subtraction osteotomy (PSO) is a surgical procedure that is frequently performed on patients with sagittal spinopelvic malalignment. Although it allows for substantial spinopelvic realignment, suboptimal realignment outcomes have been repor ... Full text Open Access Link to item Cite

Impact of spinopelvic alignment on decision making in deformity surgery in adults: A review.

Journal Article J Neurosurg Spine · June 2012 Sagittal spinal misalignment (SSM) is an established cause of pain and disability. Treating physicians must be familiar with the radiographic findings consistent with SSM. Additionally, the restoration or maintenance of physiological sagittal spinal alignm ... Full text Open Access Link to item Cite

Scoliosis Research Society-Schwab adult spinal deformity classification: a validation study.

Journal Article Spine (Phila Pa 1976) · May 20, 2012 STUDY DESIGN: Inter- and intra-rater variability study. OBJECTIVE: On the basis of a Scoliosis Research Society effort, this study seeks to determine whether the new adult spinal deformity (ASD) classification system is clear and reliable. SUMMARY OF BACKG ... Full text Open Access Link to item Cite

Dynamic changes of the pelvis and spine are key to predicting postoperative sagittal alignment after pedicle subtraction osteotomy: a critical analysis of preoperative planning techniques.

Journal Article Spine (Phila Pa 1976) · May 1, 2012 STUDY DESIGN: Retrospective, radiographical analysis of mathe-matical formulas used to predict sagittal vertical axis (SVA) after pedicle subtraction osteotomy (PSO). OBJECTIVE: Evaluate the ability of different formulas to predict SVA after PSO. SUMMARY O ... Full text Open Access Link to item Cite

Perioperative and delayed complications associated with the surgical treatment of cervical spondylotic myelopathy based on 302 patients from the AOSpine North America Cervical Spondylotic Myelopathy Study.

Journal Article J Neurosurg Spine · May 2012 OBJECT: Rates of complications associated with the surgical treatment of cervical spondylotic myelopathy (CSM) are not clear. Appreciating these risks is important for patient counseling and quality improvement. The authors sought to assess the rates of an ... Full text Open Access Link to item Cite

Sagittal spino-pelvic alignment failures following three column thoracic osteotomy for adult spinal deformity.

Journal Article Eur Spine J · April 2012 PURPOSE: Three column thoracic osteotomy (TCTO) is effective to correct rigid thoracic deformities, however, reasons for residual postoperative spinal deformity are poorly defined. Our objective was to evaluate risk factors for poor spino-pelvic alignment ... Full text Open Access Link to item Cite

High-Grade Spondylolisthesis: Reduction and Fusion Versus In Situ Fusion

Chapter · February 2, 2012 Full text Cite

Changes in thoracic kyphosis negatively impact sagittal alignment after lumbar pedicle subtraction osteotomy: a comprehensive radiographic analysis.

Journal Article Spine (Phila Pa 1976) · February 1, 2012 STUDY DESIGN: Consecutive, multicenter retrospective review. OBJECTIVE: To evaluate if change in thoracic kyphosis (TK) has a positive or negative impact on spinopelvic alignment after lumbar pedicle subtraction osteotomy (PSO) with short fusions. SUMMARY ... Full text Open Access Link to item Cite

In response

Journal Article Spine · February 1, 2012 Full text Open Access Cite

Early versus delayed decompression for traumatic cervical spinal cord injury: results of the Surgical Timing in Acute Spinal Cord Injury Study (STASCIS).

Journal Article PLoS One · 2012 BACKGROUND: There is convincing preclinical evidence that early decompression in the setting of spinal cord injury (SCI) improves neurologic outcomes. However, the effect of early surgical decompression in patients with acute SCI remains uncertain. Our obj ... Full text Open Access Link to item Cite

Multicenter validation of a formula predicting postoperative spinopelvic alignment.

Journal Article J Neurosurg Spine · January 2012 OBJECT: Sagittal spinopelvic imbalance is a major contributor to pain and disability for patients with adult spinal deformity (ASD). Preoperative planning is essential for pedicle subtraction osteotomy (PSO) candidates; however, current methods are often i ... Full text Open Access Link to item Cite

Prevalence, severity, and impact of foraminal and canal stenosis among adults with degenerative scoliosis.

Journal Article Neurosurgery · December 2011 BACKGROUND: Management approaches for adult scoliosis are primarily based on adults with idiopathic scoliosis and extrapolated to adults with degenerative scoliosis. However, the often substantially, but poorly defined, greater degenerative changes present ... Full text Open Access Link to item Cite

Effectiveness of spinal fusion versus structured rehabilitation in chronic low back pain patients with and without isthmic spondylolisthesis: a systematic review.

Journal Article Spine (Phila Pa 1976) · October 1, 2011 STUDY DESIGN: Systematic review. OBJECTIVE: To determine if the presence of isthmic spondylolisthesis modifies the effect of treatment (fusion vs. multidimensional supervised rehabilitation) in patients with chronic low back pain (CLBP). SUMMARY OF BACKGRO ... Full text Open Access Link to item Cite

Does bone morphogenetic protein increase the incidence of perioperative complications in spinal fusion? A comparison of 55,862 cases of spinal fusion with and without bone morphogenetic protein.

Journal Article Spine (Phila Pa 1976) · September 15, 2011 STUDY DESIGN: Retrospective review of a multi-institutional, multisurgeon database. OBJECTIVE: Assess for associations between bone morphogenetic protein (BMP) use and rate of complications in spinal fusion. SUMMARY OF BACKGROUND DATA: BMP is commonly used ... Full text Open Access Link to item Cite

Complications in the surgical treatment of 19,360 cases of pediatric scoliosis: a review of the Scoliosis Research Society Morbidity and Mortality database.

Journal Article Spine (Phila Pa 1976) · August 15, 2011 STUDY DESIGN: Retrospective review of a multicenter database. OBJECTIVE: To determine the complication rates associated with surgical treatment of pediatric scoliosis and to assess variables associated with increased complication rates. SUMMARY OF BACKGROU ... Full text Open Access Link to item Cite

Reliability and reproducibility of subaxial cervical injury description system: a standardized nomenclature schema.

Journal Article Spine (Phila Pa 1976) · August 1, 2011 STUDY DESIGN: Radiographic measurement study. OBJECTIVE: To develop a standardized cervical injury nomenclature system to facilitate description, communication, and classification among health care providers. The reliability and reproducibility of this sys ... Full text Open Access Link to item Cite

Monitoring.

Journal Article J Neurosurg Spine · August 2011 Full text Open Access Link to item Cite

Spinal instability neoplastic score: an analysis of reliability and validity from the spine oncology study group.

Journal Article J Clin Oncol · August 1, 2011 PURPOSE: Standardized indications for treatment of tumor-related spinal instability are hampered by the lack of a valid and reliable classification system. The objective of this study was to determine the interobserver reliability, intraobserver reliabilit ... Full text Open Access Link to item Cite

Clinical and Radiographic Factors Driving the Transition from Nonoperative to Operative Treatment in Elderly Adults with Degenerative Scoliosis

Conference JOURNAL OF NEUROSURGERY · August 1, 2011 Link to item Cite

Predictors of Success in the Surgical Treatment for Cervical Spondylotic Myelopathy: Analysis of the AOSpine North America Multi-Center Prospective Study in 260 Subjects

Conference JOURNAL OF NEUROSURGERY · August 1, 2011 Link to item Cite

Risk Factors for Major Perioperative Complications in Adult Spinal Deformity Surgery

Conference JOURNAL OF NEUROSURGERY · August 1, 2011 Link to item Cite

Use of recombinant human bone morphogenetic protein-2 (rhBMP-2) as an adjunct for instrumented posterior arthrodesis in the occipital cervical region: An analysis of safety, efficacy and dosing

Journal Article Journal of Craniovertebral Junction and Spine · July 1, 2011 Full text Open Access Cite

Safety, efficacy, and dosing of recombinant human bone morphogenetic protein-2 for posterior cervical and cervicothoracic instrumented fusion with a minimum 2-year follow-up.

Journal Article Neurosurgery · July 2011 BACKGROUND: Considerable attention has focused on concerns of increased complications with recombinant human bone morphogenetic protein-2 (rhBMP-2) use for anterior cervical fusion, but few reports have assessed its use for posterior cervical fusions. OBJE ... Full text Open Access Link to item Cite

C-2 neurectomy during atlantoaxial instrumented fusion in the elderly: patient satisfaction and surgical outcome.

Journal Article J Neurosurg Spine · July 2011 OBJECTIVE: The originally described technique of atlantoaxial stabilization using C-1 lateral mass and C-2 pars screws includes a C-2 neurectomy to provide adequate hemostasis and visualization for screw placement, enable adequate joint decortication and a ... Full text Open Access Link to item Cite

Rates of new neurological deficit associated with spine surgery based on 108,419 procedures: a report of the scoliosis research society morbidity and mortality committee.

Journal Article Spine (Phila Pa 1976) · July 1, 2011 STUDY DESIGN: Retrospective review of a prospectively collected, multicenter database. OBJECTIVE: To assess rates of new neurologic deficit (NND) associated with spine surgery. SUMMARY OF BACKGROUND DATA: NND is a potential complication of spine surgery, b ... Full text Open Access Link to item Cite

The Scoliosis Research Society Health-Related Quality of Life (SRS-30) age-gender normative data: an analysis of 1346 adult subjects unaffected by scoliosis.

Journal Article Spine (Phila Pa 1976) · June 15, 2011 STUDY DESIGN: Prospective, cross-sectional study. OBJECTIVE: To determine Scoliosis Research Society (SRS)-30 health-related quality of life (HRQOL) reference values by age and gender in an adult population unaffected by scoliosis thereby allowing clinicia ... Full text Open Access Link to item Cite

Selective versus nonselective fusion for idiopathic scoliosis: does lumbosacral takeoff angle change?

Journal Article Spine (Phila Pa 1976) · June 15, 2011 STUDY DESIGN: Retrospective review of a prospective, multicentered database. OBJECTIVE: To determine the relationship between preoperative lumbosacral takeoff angle (LSTOA) and postoperative thoracolumbar/lumbar Cobb angle (TL/L Cobb angle) in patients und ... Full text Open Access Link to item Cite

Short-term morbidity and mortality associated with correction of thoracolumbar fixed sagittal plane deformity: a report from the Scoliosis Research Society Morbidity and Mortality Committee.

Journal Article Spine (Phila Pa 1976) · May 20, 2011 STUDY DESIGN: Retrospective review. OBJECTIVE: Our objective was to assess the short-term complication rate in patients undergoing treatment of thoracolumbar fixed sagittal plane deformity (FSPD). SUMMARY OF BACKGROUND DATA: The reported morbidity and mort ... Full text Open Access Link to item Cite

Risk-benefit assessment of surgery for adult scoliosis: an analysis based on patient age.

Journal Article Spine (Phila Pa 1976) · May 1, 2011 STUDY DESIGN: Retrospective review of a prospective, multicenter database. OBJECTIVE: The purpose of this study was to assess whether elderly patients undergoing scoliosis surgery had an incidence of complications and improvement in outcome measures compar ... Full text Open Access Link to item Cite

A phase I/IIa clinical trial of a recombinant Rho protein antagonist in acute spinal cord injury.

Journal Article J Neurotrauma · May 2011 Multiple lines of evidence have validated the Rho pathway as important in controlling the neuronal response to growth inhibitory proteins after central nervous system (CNS) injury. A drug called BA-210 (trademarked as Cethrin(®)) blocks activation of Rho a ... Full text Open Access Link to item Cite

Scoliosis research society morbidity and mortality of adult scoliosis surgery.

Journal Article Spine (Phila Pa 1976) · April 20, 2011 STUDY DESIGN: A retrospective review. OBJECTIVE: To obtain an assessment of complication incidence using the largest known database of adult scoliosis and to determine whether the rate of complication depends on various clinical parameters. SUMMARY OF BACK ... Full text Open Access Link to item Cite

Rates of infection after spine surgery based on 108,419 procedures: a report from the Scoliosis Research Society Morbidity and Mortality Committee.

Journal Article Spine (Phila Pa 1976) · April 1, 2011 STUDY DESIGN: Retrospective review of a prospectively collected database. OBJECTIVE: Our objective was to assess the rates of postoperative wound infection associated with spine surgery. SUMMARY OF BACKGROUND DATA: Although wound infection after spine surg ... Full text Open Access Link to item Cite

Correlation of higher preoperative American Society of Anesthesiology grade and increased morbidity and mortality rates in patients undergoing spine surgery.

Journal Article J Neurosurg Spine · April 2011 OBJECT: Patients with varied medical comorbidities often present with spinal pathology for which operative intervention is potentially indicated, but few studies have examined risk stratification in determining morbidity and mortality rates associated with ... Full text Open Access Link to item Cite

Morbidity and mortality in the surgical treatment of six hundred five pediatric patients with isthmic or dysplastic spondylolisthesis.

Journal Article Spine (Phila Pa 1976) · February 15, 2011 STUDY DESIGN: Retrospective analysis of prospectively collected database. OBJECTIVE: To analyze the rate of complications, including neurologic deficits, associated with operative treatment of pediatric isthmic and dysplastic spondylolisthesis. SUMMARY OF ... Full text Open Access Link to item Cite

Does vertebral level of pedicle subtraction osteotomy correlate with degree of spinopelvic parameter correction?

Journal Article J Neurosurg Spine · February 2011 OBJECT: Pedicle subtraction osteotomy (PSO) is a spinal realignment technique that may be used to correct sagittal spinal imbalance. Theoretically, the level and degree of resection via a PSO should impact the degree of sagittal plane correction in the set ... Full text Open Access Link to item Cite

Incidence of unintended durotomy in spine surgery based on 108,478 cases.

Journal Article Neurosurgery · January 2011 BACKGROUND: Unintended durotomy is a common complication of spinal surgery. However, the incidences reported in the literature vary widely and are based primarily on relatively small case numbers from a single surgeon or institution. OBJECTIVE: To provide ... Full text Open Access Link to item Cite

Faced joint locking.

Journal Article J Neurosurg Spine · January 2011 Full text Open Access Link to item Cite

Morbidity and mortality associated with spinal surgery in children: a review of the Scoliosis Research Society morbidity and mortality database.

Journal Article J Neurosurg Pediatr · January 2011 OBJECT: Currently, few studies regarding morbidity and mortality associated with operative treatment of spinal disorders in children are available to guide the surgeon. This study provides more detailed morbidity and mortality data with an analysis of 23,9 ... Full text Open Access Link to item Cite

Osteoarthritis and Inflammatory Arthritides of the Aging Spine

Chapter · December 7, 2010 Full text Cite

Intraoperative electrophysiological monitoring in spine surgery.

Journal Article Spine (Phila Pa 1976) · December 1, 2010 STUDY DESIGN: Review of the literature with analysis of pooled data. OBJECTIVE: To assess common intraoperative neuromonitoring (IOM) changes that occur during the course of spinal surgery, potential causes of change, and determine appropriate responses. F ... Full text Open Access Link to item Cite

Complication rates of three common spine procedures and rates of thromboembolism following spine surgery based on 108,419 procedures: a report from the Scoliosis Research Society Morbidity and Mortality Committee.

Journal Article Spine (Phila Pa 1976) · November 15, 2010 STUDY DESIGN: Retrospective review of a prospectively collected database. OBJECTIVE: The Scoliosis Research Society (SRS) collects morbidity and mortality (M and M) data from its members. Our objectives were to assess complication rates for 3 common spine ... Full text Open Access Link to item Cite

Morbidity and mortality in the surgical treatment of 10,242 adults with spondylolisthesis.

Journal Article J Neurosurg Spine · November 2010 OBJECT: This is a retrospective review of 10,242 adults with degenerative spondylolisthesis (DS) and isthmic spondylolisthesis (IS) from the morbidity and mortality (M&M) index of the Scoliosis Research Society (SRS). This database was reviewed to assess c ... Full text Open Access Link to item Cite

Expert's comment concerning grand rounds case entitled "surgical treatment of a 180° thoracolumbar fixed kyphosis in a young achondroplastic patient: a one stage 'in situ' combined fusion and spinal cord translocation" (by J. C. Aurégan, T. Odent, M. Zerah, J.-P. Padovani and C. Glorion).

Journal Article Eur Spine J · November 2010 An expert comment is provided for the case of an 18-year-old male achondroplastic patient with a severe thoracolumbar kyphosis and spinal stenosis managed with a five level hemilaminotomy, a decancellation osteotomy of the three apical vertebrae and circum ... Full text Open Access Link to item Cite

A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group.

Journal Article Spine (Phila Pa 1976) · October 15, 2010 STUDY DESIGN: Systematic review and modified Delphi technique. OBJECTIVE: To use an evidence-based medicine process using the best available literature and expert opinion consensus to develop a comprehensive classification system to diagnose neoplastic spi ... Full text Open Access Link to item Cite

Therapeutic decision making in thoracolumbar spine trauma.

Journal Article Spine (Phila Pa 1976) · October 1, 2010 STUDY DESIGN: Systematic literature review. OBJECTIVE: A systematic review was designed to answer 3 primary research questions: (1) What is the most useful classification system for surgical and nonsurgical decision-making with regard to thoracolumbar (TL) ... Full text Open Access Link to item Cite

Changes in radiographic and clinical outcomes with primary treatment adult spinal deformity surgeries from two years to three- to five-years follow-up.

Journal Article Spine (Phila Pa 1976) · September 15, 2010 STUDY DESIGN: Retrospective analysis of data entered prospectively into a multicenter database-clinical and radiographic outcomes assessment. OBJECTIVE: Our hypothesis is that between the 2-year and the 3- to 5-year points surgically treated adult spinal d ... Full text Open Access Link to item Cite

Does Surgical Treatment for Cervical Spondylotic Myelopathy Result in Long Term Benefit? Two Year Outcomes of the AO Spine North America CSM Multi-Center Prospective Study in 280 Subjects

Conference JOURNAL OF NEUROSURGERY · August 1, 2010 Link to item Cite

Use of recombinant human bone morphogenetic protein-2 as an adjunct for instrumented posterior arthrodesis in the occipital cervical region: An analysis of safety, efficacy, and dosing

Journal Article Journal of Craniovertebral Junction and Spine · July 1, 2010 Background: There have been few reports on the use of recombinant human bone morphogenetic protein (rhBMP)-2 in posterior spine. However, no study has investigated the dosing, safety, and efficacy of its use in the posterior atlantoaxial, and/or craniovert ... Full text Open Access Cite

Morbidity and mortality in the surgical treatment of 10,329 adults with degenerative lumbar stenosis.

Journal Article J Neurosurg Spine · May 2010 OBJECT: The purpose of this study was to evaluate the prospectively collected Scoliosis Research Society (SRS) database to assess the incidences of morbidity and mortality (M&M) in the operative treatment of degenerative lumbar stenosis, one of the most co ... Full text Open Access Link to item Cite

Timing of surgery and radiotherapy in the management of metastatic spine disease: a systematic review.

Journal Article Int J Oncol · March 2010 The last decade has witnessed a dramatic change in management of metastatic spine disease, with an increased role for surgery and emerging use of stereotactic radiotherapy, often in combination. Patients may be treated with radiotherapy followed by surgery ... Link to item Cite

The costs and benefits of nonoperative management for adult scoliosis.

Journal Article Spine (Phila Pa 1976) · March 1, 2010 STUDY DESIGN: A prospective cohort of adult scoliosis patients treated nonoperatively had a minimum of 2-year follow-up during which time data were collected on the type and quantity of nonoperative treatment used. OBJECTIVE: To quantify the use, cost, and ... Full text Link to item Cite

Diagnosis and management of low lumbar burst fractures

Journal Article Seminars in Spine Surgery · March 1, 2010 Fractures of the low lumbar spine are relatively uncommon and have various injury patterns. Treatment must be individualized and should take into account the fracture type, ligamentous injury pattern, neurological injury, the limitations of surgical implan ... Full text Cite

Basilar invagination.

Journal Article Neurosurgery · March 2010 BACKGROUND: Basilar invagination is a developmental anomaly of the craniovertebral junction in which the odontoid abnormally prolapses into the foramen magnum. It is often associated with other osseous anomalies of the craniovertebral junction, including a ... Full text Link to item Cite

Timing of surgery and radiotherapy in the management of metastatic spine disease: A systematic review

Journal Article International Journal of Oncology · January 25, 2010 Full text Cite

Complications of spinal fusion for scheuermann kyphosis: a report of the scoliosis research society morbidity and mortality committee.

Journal Article Spine (Phila Pa 1976) · January 1, 2010 STUDY DESIGN: Retrospective review of a prospectively collected, multicentered database from the Scoliosis Research Society. OBJECTIVES: To evaluate incidences of complications in a series of spinal fusions for Scheuermann kyphosis (SK) and to assess wheth ... Full text Link to item Cite

Standardized measures of health status and disability and the decision to pursue operative treatment in elderly patients with degenerative scoliosis.

Journal Article Neurosurgery · January 2010 OBJECTIVE: Treatment decision making in elderly patients with degenerative scoliosis is complex. Although most patients can be adequately treated with nonoperative therapies, a subset ultimately elects for surgical treatment. However, the factors that gove ... Full text Link to item Cite

Thoracolumbar spinal deformity.

Journal Article J Neurosurg Spine · December 2009 Full text Link to item Cite

Radiosurgery in the treatment of spinal metastases: tumor control, survival, and quality of life after helical tomotherapy.

Journal Article Neurosurgery · December 2009 OBJECTIVE: The effectiveness and limitations of spinal radiosurgery using a helical TomoTherapy system for the treatment of spinal metastases are reviewed in this article. METHODS: This is a retrospective review of patients who underwent stereotactic radio ... Full text Link to item Cite

Aggressive "benign" primary spine neoplasms: osteoblastoma, aneurysmal bone cyst, and giant cell tumor.

Journal Article Spine (Phila Pa 1976) · October 15, 2009 STUDY DESIGN: Clinically based systematic review. OBJECTIVE: To define optimal clinical care for primary spinal aggressive "benign" osseous neoplasms using a systematic review with expert opinion. METHODS: Predefined focused questions on treatment of osteo ... Full text Link to item Cite

Differences between neurosurgeons and orthopedic surgeons in classifying cervical dislocation injuries and making assessment and treatment decisions: a multicenter reliability study.

Journal Article Am J Orthop (Belle Mead NJ) · October 2009 Variability exists in the management of cervical spinal injuries. The goal of this study was to assess the effect of training specialty (orthopedic surgery vs neurosurgery) on management of cervical dislocations. Twenty-nine spine surgeons reviewed 10 case ... Link to item Cite

Pain and disability determine treatment modality for older patients with adult scoliosis, while deformity guides treatment for younger patients.

Journal Article Spine (Phila Pa 1976) · September 15, 2009 STUDY DESIGN: Multi-center, retrospective review. OBJECTIVE: Identify age associated clinical and radiographic features correlating with AS treatment. SUMMARY OF BACKGROUND DATA: Little information exists about factors determining treatment for adult scoli ... Full text Link to item Cite

Does treatment (nonoperative and operative) improve the two-year quality of life in patients with adult symptomatic lumbar scoliosis: a prospective multicenter evidence-based medicine study.

Journal Article Spine (Phila Pa 1976) · September 15, 2009 STUDY DESIGN: Prospective observational cohort study with matched and unmatched comparisons. Level II evidence. OBJECTIVE: The purpose of this study is to compare results of adult symptomatic lumbar scoliosis (ASLS) patients treated nonoperatively and oper ... Full text Link to item Cite

Mean subaxial space available for the cord index as a novel method of measuring cervical spine geometry to predict the chronic stinger syndrome in American football players.

Journal Article J Neurosurg Spine · September 2009 OBJECT: The chronic stinger syndrome is a distinct entity from acute stingers and has been shown to have its own pathophysiology that, unlike acute stingers, may reflect long-standing geometrical changes of the subaxial spinal canal and chronic irritation/ ... Full text Link to item Cite

Operative versus nonoperative treatment of leg pain in adults with scoliosis: a retrospective review of a prospective multicenter database with two-year follow-up.

Journal Article Spine (Phila Pa 1976) · July 15, 2009 STUDY DESIGN: Retrospective review of a prospective, multicenter study. OBJECTIVE: The purpose of this study was to assess the prevalence and severity of leg pain in adults with scoliosis and to assess whether surgery significantly improved leg pain compar ... Full text Link to item Cite

Improvement of back pain with operative and nonoperative treatment in adults with scoliosis.

Journal Article Neurosurgery · July 2009 OBJECTIVE: The purpose of this study was to assess whether back pain is improved with surgical treatment compared with nonoperative management in adults with scoliosis. METHODS: This is a retrospective review of a prospective, multicentered database of adu ... Full text Link to item Cite

Small intestinal submucosa for anular defect closure: long-term response in an in vivo sheep model.

Journal Article Spine (Phila Pa 1976) · June 15, 2009 STUDY DESIGN: After undergoing anulotomy, lumbar intervertebral discs from sheep were treated with small intestinal submucosa (SIS) and assessed functionally at 24 weeks after surgery. OBJECTIVE: To determine the efficacy of an SIS-based patch and plug sca ... Full text Link to item Cite

Degenerative lumbar stenosis: update.

Journal Article Arq Neuropsiquiatr · June 2009 We present a literature review of the diagnosis and treatment of acquired lumbar spinal stenosis (LS), with a brief description of new surgical techniques. LS is the most common cause of spinal surgery in individuals older than 65 years of age. Neurogenic ... Full text Link to item Cite

Radiographic restoration of lumbar alignment after transforaminal lumbar interbody fusion.

Conference Neurosurgery · May 2009 OBJECTIVE: Restoration of lumbar lordosis is a critical factor in long-term success after lumbar fusions. Transforaminal lumbar interbody fusion (TLIF) is a popular surgical technique in the lumbar spine, but few data exist on change in spinal alignment af ... Full text Link to item Cite

Do 1-year outcomes predict 2-year outcomes for adult deformity surgery?

Journal Article Spine J · April 2009 BACKGROUND CONTEXT: Health-related quality-of-life (HRQOL) measures are being used more frequently in the evaluation of the adult deformity patient. This is due in part to the validation of the deformity-specific Scolios Research Society-22 (SRS-22). Hence ... Full text Link to item Cite

Magnesium efficacy in a rat spinal cord injury model.

Journal Article J Neurosurg Spine · April 2009 OBJECT: Magnesium has been shown to have neuroprotective properties in short-term spinal cord injury (SCI) studies. The authors evaluated the efficacy of magnesium, methylprednisolone, and magnesium plus methylprednisolone in a rat SCI model. METHODS: A mo ... Full text Link to item Cite

The posterior cervical foraminotomy in the treatment of cervical disc/osteophyte disease: a single-surgeon experience with a minimum of 5 years' clinical and radiographic follow-up.

Journal Article J Neurosurg Spine · April 2009 OBJECT: This study details long-term clinical and radiographic outcomes following single-level posterior cervical foraminotomy for degenerative disc or osteophyte disease. METHODS: The authors conducted a retrospective review of 162 cases involving patient ... Full text Link to item Cite

The timing and influence of MRI on the management of patients with cervical facet dislocations remains highly variable: a survey of members of the Spine Trauma Study Group.

Journal Article J Spinal Disord Tech · April 2009 BACKGROUND: Traumatic cervical facet dislocations are potentially devastating injuries. Magnetic resonance imaging (MRI) is an excellent means of assessing ligamentous disruption, disk herniation, and compression of the neural elements. However, despite an ... Full text Link to item Cite

Response

Journal Article Journal of Neurosurgery: Spine · April 1, 2009 Full text Cite

Utility of helical computed tomography in differentiating unilateral and bilateral facet dislocations.

Journal Article J Spinal Cord Med · 2009 OBJECTIVE: Diagnosis of cervical facet dislocation is difficult when relying on plain radiographs alone. This study evaluates the interobserver reliability of helical computed tomography (CT) in the assessment of cervical translational injuries, correlates ... Full text Link to item Cite

Man-in-the-barrel syndrome after thoracoilium fusion.

Journal Article J Neurosurg Spine · December 2008 The authors report a case of man-in-the-barrel (MIB) syndrome occurring after an extensive revision involving thoracoilium instrumentation and fusion for iatrogenic and degenerative scoliosis, progressive kyphosis, and sagittal imbalance. Isolated brachial ... Full text Link to item Cite

Cosmetic and functional outcomes following paramedian and anterolateral retroperitoneal access in anterior lumbar spine surgery.

Journal Article J Neurosurg Spine · November 2008 OBJECT: In this paper, the authors review the functional and cosmetic outcomes and complications in 300 patients who underwent treatment for lumbar spine disease via either an anterior paramedian or conventional anterolateral retroperitoneal approach. METH ... Full text Link to item Cite

Neurological symptoms and deficits in adults with scoliosis who present to a surgical clinic: incidence and association with the choice of operative versus nonoperative management.

Journal Article J Neurosurg Spine · October 2008 OBJECT: Adults with scoliosis often present with neurological symptoms and deficits. However, the incidence of these findings and how they may affect treatment decisions have not been clearly defined. The purpose of this study was to quantify the prevalenc ... Full text Link to item Cite

Age-gender matched comparison of SRS instrument scores between adult deformity and normal adults: are all SRS domains disease specific?

Journal Article Spine (Phila Pa 1976) · September 15, 2008 STUDY DESIGN: Prospective, observational study. OBJECTIVE: To further validate the Scoliosis Research Society (SRS) instrument by comparing scores of adult deformity patients with no prior history of spine surgery to the scores of normal adult volunteers i ... Full text Link to item Cite

Spinal deformity: a new classification derived from neutral upright spinal alignment measurements in asymptomatic juvenile, adolescent, adult, and geriatric individuals.

Journal Article Neurosurgery · September 2008 OBJECTIVE: In this literature review, the authors analyze data from previously published studies that evaluated neutral upright spinal alignment (NUSA) from the occiput to the pelvis in asymptomatic individuals. Based on the data for NUSA in asymptomatic v ... Full text Link to item Cite

Decision making in pediatric spinal deformity.

Journal Article Neurosurgery · September 2008 OBJECTIVE: To review the concepts involved in the decision-making process for management of pediatric patients with spinal deformity. METHODS: The literature was reviewed in reference to pediatric deformity evaluation and management. RESULTS: Pediatric spi ... Full text Link to item Cite

Iatrogenic spinal deformity.

Journal Article Neurosurgery · September 2008 Patients with postoperative spinal deformities are being identified with increasing frequency as the number of instrumented spinal operations increases. Thus, it is important for the neurosurgeon to understand ways to minimize postoperative deformity and t ... Full text Link to item Cite

Noninvasive measurement and screening techniques for spinal deformities.

Journal Article Neurosurgery · September 2008 OBJECTIVE: Spinal deformities are caused by a heterogeneous collection of disease processes. The progression of the scoliotic curve can vary depending on the individual patient, as well as the curve etiology. Noninvasive measurement techniques have been de ... Full text Link to item Cite

Adult degenerative scoliosis: a review.

Journal Article Neurosurgery · September 2008 OBJECTIVE: To review and define principles and features of treatment for adult degenerative scoliosis, the most common cause of adult spinal deformities. STUDY DESIGN: We conducted a comprehensive review of the literature and our clinical experience. METHO ... Full text Link to item Cite

Classification systems for adolescent and adult scoliosis.

Journal Article Neurosurgery · September 2008 OBJECTIVE: To review current classification systems for adolescent and adult scoliosis. METHODS: The literature was reviewed in reference to scoliosis classification systems for adolescent and adult scoliosis. RESULTS: There are multiple classification sys ... Full text Link to item Cite

Thoracolumbar spinal deformity: evaluation and treatment. Foreword.

Journal Article Neurosurgery · September 2008 Full text Link to item Cite

Trends in surgical management for type II odontoid fracture: 20 years of experience at a regional spinal cord injury center.

Journal Article Orthopedics · July 2008 This study reviewed surgical treatment methods in patients with type II odontoid fracture who were admitted to a level 1 spinal cord injury center during a 20-year period. Of the 186 patients who met inclusion criteria, 75 were treated operatively. The rat ... Link to item Cite

Outcomes of bone morphogenetic protein-2 in mature adults: posterolateral non-instrument-assisted lumbar decompression and fusion.

Journal Article Surg Neurol · May 2008 BACKGROUND: Bone morphogenic protein products enable lumber spine fusion. Few outcome studies have been performed to evaluate function and pain relief after posterior lumber decompression for degenerative disease, and few studies have provided detailed res ... Full text Link to item Cite

Radiographic and clinical outcomes following single-level anterior cervical discectomy and allograft fusion without plate placement or cervical collar.

Journal Article J Neurosurg Spine · May 2008 OBJECT: Although the clinical outcomes following anterior cervical discectomy and fusion (ACDF) surgery are generally good, 2 major complications are graft migration and nonunion. These complications have led some to advocate rigid internal fixation and/or ... Full text Link to item Cite

Variations in surgical treatment of cervical facet dislocations.

Journal Article Spine (Phila Pa 1976) · April 1, 2008 STUDY DESIGN: Retrospective Survey Analysis. OBJECTIVE: To explore surgeon preference in the choice of surgical approach in the treatment of traumatic cervical facet dislocations. SUMMARY OF BACKGROUND DATA: The choice of surgical approach in the treatment ... Full text Link to item Cite

Predictors of outcome with decompressive surgery for cervical spondylotic myelopathy: A prospective multicenter study in 283 patients with independent assessment

Conference JOURNAL OF NEUROSURGERY · April 1, 2008 Full text Link to item Cite

A prospective, multicenter trial to evaluate the role and timing of decompression in patients with cervical spinal cord injury: Initial one year results of the STASCIS study

Conference JOURNAL OF NEUROSURGERY · April 1, 2008 Full text Link to item Cite

The use of an expandable cage for corpectomy reconstruction of vertebral body tumors through a posterior extracavitary approach: a multicenter consecutive case series of prospectively followed patients.

Journal Article Spine J · 2008 BACKGROUND CONTEXT: Posterior decompressions in the form of laminectomies for vertebral body tumors have poor outcomes. Surgical management typically requires anterior decompression and reconstruction; however, these procedures can be associated with signi ... Full text Link to item Cite

Inflammatory and dysplastic lesions involving the spine.

Journal Article Neurosurg Clin N Am · January 2008 Dysplastic lesions of the spinal column include a wide spectrum of disorders that can occur secondary to metabolic, degenerative, and inflammatory processes. The clinical presentations are highly variable, depending on the location of the lesion and the ex ... Full text Link to item Cite

Surgical management of global sagittal deformity in ankylosing spondylitis.

Journal Article Neurosurg Focus · 2008 Ankylosing spondylitis (AS) is an inflammatory rheumatic disease whose primary effect is on the axial skeleton, causing sagittal-plane deformity at both the thoracolumbar and cervicothoracic junctions. In the present review article the authors discuss curr ... Full text Link to item Cite

Contralateral radiculopathy after transforaminal lumbar interbody fusion.

Journal Article Eur Spine J · December 2007 Transforaminal lumbar interbody fusion (TLIF) is an effective treatment for patients with degenerative spondylolisthesis and degenerative disc disease. Opposite side radiculopathy after the TLIF procedure has been recognized in this institution but has not ... Full text Link to item Cite

Cervical crossing laminar screws: Early clinical results and complications - Commentary

Journal Article Neurosurgery · November 1, 2007 Full text Cite

Technique and clinical results of minimally invasive reconstruction and stabilization of the thoracic and thoracolumbar spine with expandable cages and ventrolateral plate fixation: Commentary

Journal Article Neurosurgery · October 1, 2007 Full text Cite

Occipitocervical fusion with rigid internal fixation: long-term follow-up data in 69 patients.

Journal Article J Neurosurg Spine · August 2007 OBJECT: Instability of the occipitocervical junction may result from degenerative disease, infection, tumor, and trauma. Surgical stabilization involving screw fixation and rigid implants has been found to be biomechanically superior to wire-based implants ... Full text Link to item Cite

Observations on spine deformity and syringomyelia: Commentary

Journal Article Neurosurgery · August 1, 2007 Full text Cite

Congenital abnormalities of the thoracic and lumbar spine.

Journal Article Neurosurg Clin N Am · July 2007 Congenital spinal anomalies entail a wide spectrum of conditions that share in common some form of error during embryogenesis. Congenital disorders of the spine may not always be readily apparent at birth; they can present as a deformity with growth or wit ... Full text Link to item Cite

SF-36 PCS benefit-cost ratio of lumbar fusion comparison to other surgical interventions: a thought experiment.

Journal Article Spine (Phila Pa 1976) · May 15, 2007 STUDY DESIGN: A retrospective review of prospectively collected data. OBJECTIVES: To review systematically the SF-36 PCS outcomes of a large data set, including several randomized clinical trials for lumbar spine fusion at 1 and 2 years after surgery. We a ... Full text Link to item Cite

Results of the cethrin phase I/IIa prospective clinical trial of a rho inhibitor for the treatment of acute spinal cord injury

Conference JOURNAL OF NEUROSURGERY · April 1, 2007 Link to item Cite

Traumatic loading of the bryan cervical disc prosthesis: An in vitro study - Commentary

Journal Article Neurosurgery · April 1, 2007 Full text Cite

Return of normal urological and neurological function after revision surgery for spondyloptosis. Case report.

Journal Article J Neurosurg Spine · March 2007 The authors report on the return of neurological and urological function in an adolescent after revision surgery for spondyloptosis 5 years after the index procedure for high-grade spondylolisthesis. This 16-year-old girl with Grade 3 spondylolisthesis was ... Full text Link to item Cite

Unusual presentation of an adult intramedullary spinal teratoma with diplomyelia.

Journal Article Surg Neurol · February 2007 BACKGROUND: Spinal teratomas are rare lesions. The authors present an intramedullary spinal teratoma associated with diplomyelia. CASE DESCRIPTION: This 34-year-old female patient presented with right lower extremity weakness, left lower extremity sensory ... Full text Link to item Cite

Neutral upright sagittal spinal alignment from the occiput to the pelvis in asymptomatic adults: a review and resynthesis of the literature.

Journal Article J Neurosurg Spine · February 2007 OBJECT: An increasing emphasis is being placed on the preservation or restoration of neutral upright sagittal spinal alignment in both deformity surgery and routine spinal operations. Sagittal spinal alignment is becoming recognized as an important predict ... Full text Link to item Cite

Part II: spinal-cord neoplasms--primary tumours of the bony spine and adjacent soft tissues.

Journal Article Lancet Oncol · February 2007 Primary tumours of the bony spine and adjacent soft tissues most frequently present with pain although neurological deficits and spinal deformity can be present too. Knowledge of the spectrum of lesions that can affect the bony spine and the surrounding so ... Full text Link to item Cite

Dorsal surgery for myelopathy and myeloradiculopathy.

Journal Article Neurosurgery · January 2007 OBJECTIVE: To review the dorsal approaches to the cervical spine for myelopathy and myeloradiculopathy. METHODS: The literature was reviewed in reference to dorsal approaches for cervical myelopathy and myeloradiculopathy. RESULTS: There are a variety of s ... Full text Link to item Cite

Aging spine: challenges and emerging techniques.

Journal Article Clin Neurosurg · 2007 Link to item Cite

Cervical spine injuries in pediatric athletes: mechanisms and management.

Journal Article Neurosurg Focus · October 15, 2006 Sports-related injuries to the spine, although relatively rare compared with head injuries, contribute to significant morbidity and mortality in children. The reported incidence of traumatic cervical spine injury in pediatric athletes varies, and most stud ... Full text Link to item Cite

A method for calculating the exact angle required during pedicle subtraction osteotomy for fixed sagittal deformity: Comparison with the trigonometric method - Commentary

Journal Article Neurosurgery · October 1, 2006 Full text Cite

Anterior stabilization of three-column thoracolumbar spinal trauma.

Journal Article J Neurosurg Spine · July 2006 OBJECT: The purpose of this study was to evaluate the results obtained in patients who underwent anterior stabilization for three-column thoracolumbar fractures. METHODS: The authors retrospectively reviewed available clinical and radiographic data (1997-2 ... Full text Link to item Cite

Degenerative lumbar scoliosis.

Journal Article Neurosurg Clin N Am · July 2006 In adults, symptomatic scoliosis is usually a de novo primary degenerative deformity that develops in the fifth or sixth decade or an unrecognized or untreated idiopathic deformity with superimposed degeneration. The evaluation and treatment of adult scoli ... Full text Link to item Cite

A novel and reproducible mouse model of spinal cord ischemia/reperfusion injury

Journal Article Topics in Spinal Cord Injury Rehabilitation · June 1, 2006 Background: To apply the power of mice genetics to the study of spinal cord injury (SCI), improved small animal injury models are needed. We describe a novel ischemia/reperfusion murine model that is induced by spinal cord compression that can be reproduce ... Full text Cite

Validation of digital radiology measurement tools for quantitative spinal imaging

Journal Article Topics in Spinal Cord Injury Rehabilitation · June 1, 2006 Background/Objective: Digital imaging tools for linear and angular measurements facilitate measurement requirements compared to conventional techniques. However, the accuracy of these measurement, especially in spinal trauma, has nol been assessed. The obj ... Full text Cite

Intrarater and interrater reliability and validity in the assessment of the mechanism of injury and integrity of the posterior ligamentous complex: a novel injury severity scoring system for thoracolumbar injuries. Invited submission from the Joint Section Meeting On Disorders of the Spine and Peripheral Nerves, March 2005.

Conference J Neurosurg Spine · February 2006 OBJECT: A new classification and treatment algorithm for thoracolumbar injuries was recently introduced by Vaccaro and colleagues in 2005. A thoracolumbar injury severity scale (TLISS) was proposed for grading and guiding treatment for these injuries. The ... Full text Link to item Cite

Complications in spinal fusion for adolescent idiopathic scoliosis in the new millennium. A report of the Scoliosis Research Society Morbidity and Mortality Committee.

Journal Article Spine (Phila Pa 1976) · February 1, 2006 STUDY DESIGN: The Morbidity and Mortality database of the Scoliosis Research Society (SRS) was queried as to the incidence and type of complications as reported by its members for the treatment of adolescent idiopathic scoliosis (AIS) with spinal fusion an ... Full text Link to item Cite

Thoracolumbar vertebral reconstruction after surgery for metastatic spinal tumors: long-term outcomes.

Journal Article Neurosurg Focus · September 15, 2005 OBJECT: Metastatic spinal tumors continue to represent a major problem for patients and treating physicians. The purpose of this study was to assess quantitatively the functional outcome, quality of life, and survival rates of patients after major reconstr ... Full text Link to item Cite

Iliac crest bone graft donor site pain after anterior lumbar interbody fusion: a prospective patient satisfaction outcome assessment.

Journal Article J Spinal Disord Tech · February 2005 BACKGROUND: Autogenous iliac crest bone is the gold-standard graft for spinal fusion surgery. Unfortunately, there is a frequent incidence of graft site pain that persists well into the postoperative period with complication rates reported in 2.8-39% of pa ... Full text Link to item Cite

Osteoradionecrosis mimicking metastatic epidural spinal cord compression.

Journal Article Neurology · January 25, 2005 Full text Link to item Cite

Corpectomy and reconstruction of anterior vertebral body tumors with an expandable cage through a posterior only extracavitary approach

Conference JOURNAL OF BONE AND MINERAL RESEARCH · January 1, 2005 Link to item Cite

Aneurysmal bone cyst of the atlas: successful treatment through selective arterial embolization: case report.

Journal Article Neurosurgery · October 2004 OBJECTIVE AND IMPORTANCE: Aneurysmal bone cysts (ABCs) are benign and expansile osteolytic lesions that can occur in any location in the spine, including the craniovertebral junction. Aggressive resection followed by bone grafting has been the mainstay of ... Full text Link to item Cite

The future of spinal arthroplasty: a biomaterial perspective.

Journal Article Neurosurg Focus · September 15, 2004 Both total hip and knee arthroplasty have demonstrated outstanding clinical results. The functional spinal unit composed of the intervertebral disc and facet joints is at least as complex. The intricacies of the coupled motions of the functional spinal uni ... Full text Link to item Cite

The association of lumbar spondylolisthesis with collagen IX tryptophan alleles.

Journal Article J Bone Joint Surg Br · September 2004 Two collagen type IX gene polymorphisms that introduce a tryptophan residue into the protein's triple-helical domain have been linked to an increased risk of lumbar disc disease. To determine whether a particular subset of symptomatic lumbar disease is spe ... Full text Link to item Cite

Similarities and differences in the treatment of spine trauma between surgical specialties and location of practice.

Journal Article Spine (Phila Pa 1976) · March 15, 2004 STUDY DESIGN: Questionnaires administered to practicing orthopedic and neurosurgical spine surgeons from various regions of the United States and abroad. OBJECTIVES: To determine similarities and differences in the treatment of spinal trauma. SUMMARY OF BA ... Full text Link to item Cite