William Everett Copeland

Journal Article Population Research and Policy Review · June 1, 2025 Working age (25–64) mortality in the US has been increasing for decades, driven in part by rising deaths due to drug overdose, as well as increases in suicide and alcohol-related mortality. These deaths have been hypothesized by some to be due to despair, ... Full text Cite

Associations between daily wellness behaviours and outcomes among medical students: A longitudinal nightly survey study.

Journal Article Med Educ · May 22, 2025 BACKGROUND: Previous research on medical student wellbeing has examined single wellness-related behaviours in isolation and relied on cross-sectional or pre-post surveys. The objective of this study was to use daily, app-based surveys to examine which well ... Full text Link to item Cite

Impact of young adult life transitions on adult mental health problems: a propensity score analysis.

Journal Article Psychol Med · May 19, 2025 BACKGROUND: Mental health problems commonly persist from childhood to adulthood. This study tested whether young adult life transitions can improve adult mental health symptoms after adjusting for childhood mental health symptoms. METHODS: The analysis use ... Full text Link to item Cite

Do Children's Mental Health Symptoms Impact Their Access to Unlocked Guns at Home?

Journal Article J Am Acad Child Adolesc Psychiatry · April 23, 2025 OBJECTIVE: To test whether changes in children's and adolescents' mental health symptoms predict changes in their access to unlocked guns at home. METHOD: This study used data from a longitudinal cohort study of 1,420 youth and their parents in the southea ... Full text Link to item Cite

Ambient air pollution and depressed mood in the National Longitudinal Study of Adolescent to Adult Health (Add Health) wave 4.

Journal Article Am J Epidemiol · April 8, 2025 Depression is a major contributor to the global burden of disease. There is limited understanding of how environmental exposures may contribute to depression etiology. We used wave 4 of the National Longitudinal Study of Adolescent to Adult Health (Add Hea ... Full text Link to item Cite

The substance use behaviors change of first-year college students before and during COVID-19 pandemic.

Journal Article J Am Coll Health · April 2025 OBJECTIVE: This article tests the substance use behaviors of college students before and during COVID-19 pandemic. METHODS: In-depth assessment and nightly survey data was used from a longitudinal study (n = 675) which examined student substance use during ... Full text Link to item Cite

Longitudinal associations of trauma exposure with disordered eating: lessons from the Great Smoky Mountains Study

Chapter · January 27, 2025 Full text Cite

Hair Cortisol Concentrations in the Prediction of Early Substance Use Engagement in Youth.

Journal Article Subst Use Misuse · 2025 OBJECTIVE: Understanding factors associated with early onset of substance use is critical as using alcohol or drugs at a young age is a strong predictor of later substance dependency. Experiencing stressful life events is associated with increased risk for ... Full text Link to item Cite

Taking John Schulenberg's "long view" on successful transitions to adulthood: Associations with adult substance use.

Journal Article J Res Adolesc · December 2024 Can positive transitions into young adulthood at age 25 prevent problematic substance use at age 31, even in the context of childhood adverse family environments, conduct problems, and adolescent substance use? We lean on John Schulenberg's developmental f ... Full text Link to item Cite

Pathways to health: A longitudinal examination of protective factors in children with and without preschool anxiety.

Journal Article Dev Psychopathol · November 25, 2024 Preschool anxiety is highly prevalent and well known to predict risk for future psychopathology. The present study explores whether a diagnosis of an anxiety disorder in preschool interacts with (a) social skills and (b) cognitive ability to longitudinally ... Full text Link to item Cite

In Reply.

Journal Article Acad Med · November 1, 2024 Full text Link to item Cite

Lagged effects of childhood depressive symptoms on adult epigenetic aging.

Journal Article Psychol Med · October 7, 2024 BACKGROUND: Cross-sectional studies have identified health risks associated with epigenetic aging. However, it is unclear whether these risks make epigenetic clocks 'tick faster' (i.e. accelerate biological aging). The current study examines concurrent and ... Full text Link to item Cite

Tracking Well-Being: A Comprehensive Analysis of Physical Activity and Mental Health in College Students Across COVID-19 Phases Using Ecological Momentary Assessment.

Journal Article Scand J Med Sci Sports · October 2024 Physical activity (PA) is a critical factor in maintaining mental health, particularly among college students who are vulnerable to stress, anxiety, and mood disturbances. The COVID-19 pandemic introduced unprecedented disruptions to daily routines. The pu ... Full text Link to item Cite

Intergenerational effects of a casino-funded family transfer program on educational outcomes in an American Indian community.

Journal Article Nat Commun · September 17, 2024 Cash transfer policies have been widely discussed as mechanisms to curb intergenerational transmission of socioeconomic disadvantage. In this paper, we take advantage of a large casino-funded family transfer program introduced in a Southeastern American In ... Full text Link to item Cite

The Impact of Childhood Mental Health and Substance Use on Methylation Aging Into Adulthood.

Journal Article J Am Acad Child Adolesc Psychiatry · August 2024 OBJECTIVE: To test whether childhood mental health symptoms, substance use, and early adversity accelerate the rate of DNA methylation (DNAm) aging from adolescence to adulthood. METHOD: DNAm was assayed from blood samples in 381 participants in both adole ... Full text Link to item Cite

Negative Life Events and Emotional Symptoms From Ages 2 to 30 Years.

Journal Article JAMA Netw Open · August 1, 2024 IMPORTANCE: Exposure to different types of negative life events, including traumatic events, is common across the lifespan and associated with increased mental health symptoms. OBJECTIVE: To assess whether vulnerability to negative life events varies acros ... Full text Link to item Cite

Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.

Journal Article medRxiv · July 5, 2024 The major anxiety disorders (ANX; including generalized anxiety disorder, panic disorder, and phobias) are highly prevalent, often onset early, persist throughout life, and cause substantial global disability. Although distinct in their clinical presentati ... Full text Link to item Cite

The biological embedding of social adversity: How adolescent housing insecurity impacts inflammation over time.

Journal Article Brain Behav Immun · July 2024 BACKGROUND & PURPOSE: Adolescent housing insecurity is a dynamic form of social adversity that impacts child health outcomes worldwide. However, the means by which adolescent housing insecurity may become biologically embedded to influence health outcomes ... Full text Link to item Cite

Early life adversity and psychopathology in preschoolers: mechanisms and moderators.

Journal Article Eur Child Adolesc Psychiatry · June 2024 Developmental theories suggest that exposure to early life adversity (ELA) alters developing emotional response systems, predicting risk for psychopathology across the life span. The present study examines whether negative emotionality (NE), a trait-like m ... Full text Link to item Cite

The Potential of Real-Time Behavior and Well-Being Assessments to Improve Medical Student Wellness.

Journal Article Acad Med · June 1, 2024 PROBLEM: Medical students experience psychological distress more frequently than age-matched peers. Tracking medical student well-being has typically been limited to once- or twice-per-year questionnaires. Ongoing, real-time assessment of student behavior ... Full text Link to item Cite

Using Wearable Digital Devices to Screen Children for Mental Health Conditions: Ethical Promises and Challenges.

Journal Article Sensors (Basel) · May 18, 2024 In response to a burgeoning pediatric mental health epidemic, recent guidelines have instructed pediatricians to regularly screen their patients for mental health disorders with consistency and standardization. Yet, gold-standard screening surveys to evalu ... Full text Link to item Cite

Commentary: Integrative, multi-level explanatory models are needed to understand recent trends in sex, gender, and internalizing conditions, reflections on Keyes and Platt (2023).

Journal Article J Child Psychol Psychiatry · April 2024 Keyes' and Platt's (The Journal of Child Psychology and Psychiatry, 2023) review provides much-needed systematic evidence about why internalizing symptoms have increased and it clarifies the role of novel risk factors. The findings highlight that multiple ... Full text Link to item Cite

Intergenerational Effects of a Family Cash Transfer on the Home Environment.

Journal Article J Am Acad Child Adolesc Psychiatry · March 2024 OBJECTIVE: A natural experiment that provided income supplements to families has been associated with beneficial outcomes for children that persisted into adulthood. The children in this study are now adults, and many are parents. METHOD: The study builds ... Full text Link to item Cite

Associations Between Configurations of Childhood Adversity and Adult Mental Health Disorder Outcomes.

Journal Article Soc Ment Health · March 2024 The life course perspective and cumulative inequality theory suggest that childhood adversity, occurring during a sensitive period of the life course, can have long-term consequences for adult mental health and well-being. Yet, the long-term influence of a ... Full text Link to item Cite

Intergenerational Effects of the Fast Track Intervention on Next-Generation Child Outcomes: A Preregistered Randomized Clinical Trial.

Journal Article Am J Psychiatry · March 1, 2024 OBJECTIVE: The authors sought to determine whether the Fast Track mental health intervention delivered to individuals in childhood decreased mental health problems and the need for health services among the children of these individuals. METHODS: The autho ... Full text Link to item Cite

Family cash transfers in childhood and birthing persons and birth outcomes later in life.

Journal Article SSM Popul Health · March 2024 Much literature in the US documents an intergenerational transmission of birthing person and perinatal morbidity in socioeconomically disadvantaged groups. A separate line of work indicates that family cash transfers may improve life chances of low-income ... Full text Link to item Cite

Comparative assessment of the feasibility and validity of daily activity space in urban and non-urban settings.

Journal Article PLoS One · 2024 Activity space research explores the behavioral impact of the spaces people move through in daily life. This research has focused on urban settings, devoting little attention to non-urban settings. We examined the validity of the activity space method, com ... Full text Link to item Cite

Expecting the Unexpected: Predicting Panic Attacks From Mood, Twitter, and Apple Watch Data.

Journal Article IEEE Open J Eng Med Biol · 2024 OBJECTIVE: Panic attacks are an impairing mental health problem that affects 11% of adults every year. Current criteria describe them as occurring without warning, despite evidence suggesting individuals can often identify attack triggers. We aimed to pros ... Full text Link to item Cite

Child Mental Health, Family Circumstance, and Long-Term Success The Effect of Household Income

Journal Article Journal of Human Resources · January 1, 2024 We use data from a long-running experiment in which American Indian households received income transfers from a casino, while other households did not. Using a difference-in-difference analysis, we find that the treated children had fewer depression and an ... Full text Cite

Correction: Parental supervision positively impacts children's economic prospects two decades later: A prospective longitudinal study.

Journal Article PLoS One · 2024 [This corrects the article DOI: 10.1371/journal.pone.0286218.]. ... Full text Link to item Cite

A Pilot Randomized Controlled Trial of the Family Assessment and Feedback Intervention (FAFI): Effects on Mental Health Literacy and Attitudinal Engagement with Health Supports and Services

Journal Article Child Psychiatry and Human Development · January 1, 2024 This randomized controlled trial tested the Family Assessment and Feedback Intervention (FAFI), a new intervention to enhance family engagement with emotional and behavioral health services. The FAFI is a guided conversation with families about results of ... Full text Cite

Cultural contributions to adults' self-rated mental health problems and strengths: 7 culture clusters, 28 societies, 16 906 adults.

Journal Article Psychol Med · December 2023 BACKGROUND: It is unknown how much variation in adult mental health problems is associated with differences between societal/cultural groups, over and above differences between individuals. METHODS: To test these relative contributions, a consortium of ind ... Full text Link to item Cite

Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis.

Journal Article Lancet Psychiatry · December 2023 BACKGROUND: The youngest children in a school class are more likely than the oldest to be diagnosed with ADHD, but this relative age effect is less frequent in older than in younger school-grade children. However, no study has explored the association betw ... Full text Link to item Cite

Adult Mental Health, Substance Use Disorders, and Functional Outcomes of Children Resilient to Early Adversity.

Journal Article Am J Psychiatry · December 1, 2023 OBJECTIVE: Some children are unaffected by mental illness despite exposure to childhood adversity. These children are typically considered resilient. The objective of this study was to follow up such resilient children in adulthood to characterize mental h ... Full text Link to item Cite

The ChAMP App: A Scalable mHealth Technology for Detecting Digital Phenotypes of Early Childhood Mental Health.

Preprint · November 29, 2023 Full text Link to item Cite

The ChAMP App: A Scalable mHealth Technology for Detecting Digital Phenotypes of Early Childhood Mental Health.

Journal Article IEEE J Biomed Health Inform · November 29, 2023 Childhood mental health problems are common, impairing, and can become chronic if left untreated. Children are not reliable reporters of their emotional and behavioral health, and caregivers often unintentionally under- or over-report child symptoms, makin ... Full text Link to item Cite

Violent Experiences and Patterns of Firearm Ownership From Childhood to Young Adulthood.

Journal Article JAMA Netw Open · October 2, 2023 IMPORTANCE: Young adults in their 20s are at high relative risk for self- and other-directed firearm injury, but little is known about gun access patterns for this group. OBJECTIVE: To describe the longitudinal patterns of firearm access from childhood to ... Full text Link to item Cite

The Vermont Family Based Approach in Primary Care Pediatrics: Effects on Children's and Parents' Emotional and Behavioral Problems and Parents' Health-Related Quality of Life.

Journal Article Child Psychiatry Hum Dev · October 2023 This randomized controlled trial tested the Vermont Family Based Approach (VFBA) in primary care pediatrics. The VFBA is a model of healthcare delivery that shifts the focus from the individual to the family, emphasizes emotional and behavioral health, and ... Full text Link to item Cite

Pubertal timing moderates the same-day coupling between family hassles and negative affect in girls and boys.

Journal Article Dev Psychopathol · October 2023 This study examined the association between pubertal timing, daily affect, conduct problems, and the exposure to hassles across family, peer, and school contexts. Adolescents (M age = 12.27; 49.7% female; 62.6% White) completed ecological momentary assessm ... Full text Link to item Cite

A Deadly Drop in Rankings: How the United States Was Left Behind in Global Life Expectancy Trends.

Journal Article Am J Public Health · September 2023 Full text Link to item Cite

Distinct Associations of Deprivation and Threat With Alterations in Brain Structure in Early Childhood.

Journal Article J Am Acad Child Adolesc Psychiatry · August 2023 OBJECTIVE: The dimensional model of adversity and psychopathology hypothesizes deprivation and threat impact distinct neurobiological pathways, such as brain structure. This hypothesis has not been examined longitudinally or in young children. This study t ... Full text Link to item Cite

Prospective Associations of Childhood Housing Insecurity With Anxiety and Depression Symptoms During Childhood and Adulthood.

Journal Article JAMA Pediatr · August 1, 2023 IMPORTANCE: Childhood housing insecurity has dramatically increased in the US in recent decades, but whether an association with adverse mental health outcomes exists after adjusting for repeated measures of childhood poverty is unclear. OBJECTIVE: To test ... Full text Link to item Cite

Methylome-wide association study of anxiety disorders.

Journal Article Mol Psychiatry · August 2023 Anxiety Disorders (ANX) such as panic disorder, generalized anxiety disorder, and phobias, are highly prevalent conditions that are moderately heritable. Evidence suggests that DNA methylation may play a role, as it is involved in critical adaptations to c ... Full text Link to item Cite

Discovering Digital Biomarkers of Panic Attack Risk in Consumer Wearables Data.

Conference Annu Int Conf IEEE Eng Med Biol Soc · July 2023 Panic attacks are an impairing mental health problem that impacts more than one out of every 10 adults in the United States (US). Clinical guidelines suggest panic attacks occur without warning and their unexpected nature worsens their impact on quality of ... Full text Link to item Cite

Adult criminal outcomes of juvenile justice involvement.

Journal Article Psychol Med · June 2023 BACKGROUND: The juvenile justice system in the USA adjudicates over seven hundred thousand youth in the USA annually with significant behavioral offenses. This study aimed to test the effect of juvenile justice involvement on adult criminal outcomes. METHO ... Full text Link to item Cite

Day-to-day variation in adolescent food insecurity.

Journal Article Child Youth Serv Rev · June 2023 This study examined differences in both average and variability in daily adolescent food insecurity, by adolescents' levels of economic disadvantage and race/ethnicity. We used data from a 14-day ecological momentary assessment of 395 adolescents enrolled ... Full text Link to item Cite

Associations of preschool reactive bed-sharing with sociodemographic factors, sleep disturbance, and psychopathology.

Journal Article Child Adolesc Psychiatry Ment Health · May 17, 2023 OBJECTIVE: To advance understanding of early childhood bed-sharing and its clinical significance, we examined reactive bed-sharing rates, sociodemographic correlates, persistence, and concurrent and longitudinal associations with sleep disturbances and psy ... Full text Link to item Cite

Intergenerational effects of the Fast Track intervention on the home environment: A randomized control trial.

Journal Article J Child Psychol Psychiatry · May 2023 BACKGROUND: Maladaptive family environments harm child development and are passed across generations. Childhood interventions may break this intergenerational cycle by improving the family environments children form as adults. The present study investigate ... Full text Link to item Cite

Discovering Digital Biomarkers of Panic Attack Risk in Consumer Wearables Data.

Preprint · March 6, 2023 Full text Link to item Cite

Defining despair: Assessing the multidimensionality of despair and its association with suicidality and substance use in early to middle adulthood.

Journal Article Soc Sci Med · March 2023 Despite considerable scientific interest in documenting growing despair among U.S. adults, far less attention has been paid to defining despair and identifying appropriate measures. Emerging perspectives from social science and psychiatry outline a compreh ... Full text Link to item Cite

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders.

Journal Article Nat Ment Health · March 2023 Genetic liability to substance use disorders can be parsed into loci that confer general or substance-specific addiction risk. We report a multivariate genome-wide association meta-analysis that disaggregates general and substance-specific loci for publish ... Full text Link to item Cite

Fast Track intervention effects on family formation.

Journal Article J Fam Psychol · February 2023 The present study examines whether the Fast Track (FT) intervention, a 10-year randomized controlled trial with children at risk for conduct problems, affects family formation in adulthood, as indexed by partnerships, parenthood, and family structure, and ... Full text Link to item Cite

Expecting the Unexpected: Predicting Panic Attacks from Mood and Twitter

Preprint · January 29, 2023 Full text Cite

Childhood loneliness as a specific risk factor for adult psychiatric disorders.

Journal Article Psychol Med · January 2023 BACKGROUND: Loneliness is a major risk factor for both psychological disturbance and poor health outcomes in adults. This study aimed to assess whether childhood loneliness is associated with a long-term disruption in mental health that extends into adulth ... Full text Link to item Cite

The HOME-21: A revised measure of the home environment for the 21st century tested in two independent samples.

Journal Article Psychol Assess · January 2023 For decades, the Home Observation for Measurement of the Environment (HOME) has been the most widely used measure of children's home environments. This report provides a revised version of the HOME-Short Form, the HOME-21, reflecting historical changes in ... Full text Link to item Cite

Peruvian National Survey of Mental Health and Service Utilization in the third year of the COVID-19 pandemic: Protocol for a nationally representative multistage survey

Preprint · 2023 Full text Cite

Parental supervision positively impacts children's economic prospects two decades later: A prospective longitudinal study.

Journal Article PLoS One · 2023 IMPORTANCE: Upward income mobility is associated with better health outcomes and reduced stress. However, opportunities are unequally distributed, particularly so for those in rural communities and whose family have lower educational attainment. OBJECTIVE: ... Full text Link to item Cite

DNA methylation biomarkers of alcohol use disorder

Conference ALCOHOL-CLINICAL AND EXPERIMENTAL RESEARCH · 2023 Cite

Gun violence among young adults with a juvenile crime record in North Carolina: Implications for firearm restrictions based on age and risk.

Journal Article Prev Med · December 2022 Youth who acquire a juvenile crime record may be at increased risk of perpetrating gun violence as adults. North Carolina and 22 other states permit young adults who were adjudicated by a juvenile court - even for some felony-equivalent offenses - to legal ... Full text Link to item Cite

Adolescent depression and adult labor market marginalization: a longitudinal cohort study.

Journal Article Eur Child Adolesc Psychiatry · November 2022 Adolescent depression is linked to adult ill-health and functional impairment, but recent research suggests that individual/contextual factors might account for this association. This study aimed to test whether the clinical heterogeneity of adolescent dep ... Full text Link to item Cite

Parental perception of mental health needs in young children.

Journal Article Child Adolesc Ment Health · November 2022 BACKGROUND: There is evidence of unmet psychiatric needs in children under 6. These young children are dependent on their parents to identify their mental health needs. This study tested child and parent associations with parent perception of young child m ... Full text Link to item Cite

Early adversities accelerate epigenetic aging into adulthood: a 10-year, within-subject analysis.

Journal Article J Child Psychol Psychiatry · November 2022 BACKGROUND: Longitudinal studies are needed to clarify whether early adversities are associated with advanced methylation age or if they actually accelerate methylation aging. This study test whether different dimensions of childhood adversity accelerate b ... Full text Link to item Cite

Identifying adolescents at risk for depression: Assessment of a global prediction model in the Great Smoky Mountains Study.

Journal Article J Psychiatr Res · November 2022 The Identifying Depression Early in Adolescence Risk Score (IDEA-RS) has been externally assessed in samples from four continents, but North America is lacking. Our aim here was to evaluate the performance of the IDEA-RS in predicting future onset of Major ... Full text Link to item Cite

Disentangling the "who" and "when" of parents' depressive symptoms: A daily diary study analysis.

Journal Article J Psychopathol Clin Sci · October 2022 Parents' depressive symptoms vary across days, but factors predicting this fluctuation are not well understood. The present study utilized ecological momentary assessments to capture 1620 days of parents' lived experience in a diverse sample of 146 mothers ... Full text Link to item Cite

Long-term Outcomes of Childhood Family Income Supplements on Adult Functioning.

Journal Article JAMA Pediatr · October 1, 2022 IMPORTANCE: During an ongoing longitudinal cohort study, a casino opening created a natural cash transfer experiment. Some participating families received income supplements, and others did not. The children in this study are now adults. OBJECTIVE: To asse ... Full text Link to item Cite

1.79 Parental Supervision Positively Impacts Their Children’s Income Two Decades Later

Journal Article Journal of the American Academy of Child & Adolescent Psychiatry · October 2022 Full text Cite

METHYLOME-WIDE ASSOCIATION STUDY OF ANXIETY DISORDERS

Journal Article European Neuropsychopharmacology · October 2022 Full text Cite

Do "Real World" Childhood Mental Health Services Reduce Risk for Adult Psychiatric Disorders?

Journal Article J Am Acad Child Adolesc Psychiatry · August 2022 OBJECTIVE: This study tested the "intervention as prevention" hypothesis: that treatment of childhood psychopathology in the community might reduce risk for adult psychopathology. METHOD: Analyses were based on a prospective, population-based study of 1,42 ... Full text Link to item Cite

DNA methylation signatures of childhood trauma predict psychiatric disorders and other adverse outcomes 17 years after exposure.

Journal Article Mol Psychiatry · August 2022 Childhood trauma is robustly linked to a broad range of adverse outcomes with consequences persisting far into adulthood. We conducted a prospective longitudinal study to predict psychiatric disorders and other adverse outcomes from trauma-related methylat ... Full text Link to item Cite

A methylation study implicates the rewiring of brain neural circuits during puberty in the emergence of sex differences in depression symptoms.

Journal Article J Child Psychol Psychiatry · July 2022 BACKGROUND: Women are 1.5-3 times more likely to suffer from depression than men. This sex bias first emerges during puberty and then persists across the reproductive years. As the cause remains largely elusive, we performed a methylation-wide association ... Full text Link to item Cite

Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms.

Journal Article J Am Acad Child Adolesc Psychiatry · July 2022 OBJECTIVE: To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. METHOD: In 22 cohorts, multiple univariate genome-wide association studies (GWASs) were performed using repeated assessments of internalizing symptom ... Full text Link to item Cite

A Pilot Trial of a Health Promotion and Illness Prevention Paradigm in the Perinatal Period.

Journal Article Matern Child Health J · June 2022 OBJECTIVES: This is a pilot study of the Vermont Family Based Approach, an innovative health promotion program designed to address behavioral health prevention in primary care, adapted for perinatal women. We aimed to determine the acceptability of the int ... Full text Link to item Cite

Association of adversity with psychopathology in early childhood: Dimensional and cumulative approaches.

Journal Article Depress Anxiety · June 2022 BACKGROUND: The association between adversity and psychopathology in adolescents and adults is characterized by equifinality. These associations, however, have not been assessed during early childhood when psychopathology first emerges. Defining adversity ... Full text Link to item Cite

Impact of dimensions of early adversity on adult health and functioning: A 2-decade, longitudinal study.

Journal Article Dev Psychopathol · May 2022 Recent neurodevelopmental and evolutionary theories offer strong theoretical rationales and some empirical evidence to support the importance of specific dimensions of early adversity. However, studies have often been limited by omission of other adversity ... Full text Link to item Cite

COVID-related distress, mental health, and substance use in adolescents and young adults.

Journal Article Child Adolesc Ment Health · May 2022 BACKGROUND: This study examined the impact of COVID-related disruptions on mental health and substance use in young people residing in a state with an initially lower COVID burden and earlier reopening of in-person learning than other states. METHODS: Data ... Full text Link to item Cite

Adult Psychiatric, Substance, and Functional Outcomes of Different Definitions of Early Cannabis Use.

Journal Article J Am Acad Child Adolesc Psychiatry · April 2022 OBJECTIVE: Research on associations of early cannabis use with adult functioning reports mixed findings. This may be due, in part, to wide variations in the definitions of early cannabis use. This study aims to compare associations of 4 commonly used defin ... Full text Link to item Cite

Dual methylation and hydroxymethylation study of alcohol use disorder.

Journal Article Addict Biol · March 2022 Using an integrative, multi-tissue design, we sought to characterize methylation and hydroxymethylation changes in blood and brain associated with alcohol use disorder (AUD). First, we used epigenomic deconvolution to perform cell-type-specific methylome-w ... Full text Link to item Cite

A Digital Therapeutic Intervention Delivering Biofeedback for Panic Attacks (PanicMechanic): Feasibility and Usability Study.

Journal Article JMIR Form Res · February 3, 2022 BACKGROUND: Panic attacks (PAs) are an impairing mental health problem that affects >11% of adults every year. PAs are episodic, and it is difficult to predict when or where they may occur; thus, they are challenging to study and treat. OBJECTIVE: The aim ... Full text Link to item Cite

Ecological Momentary Assessment of Physical Activity and Wellness Behaviors in College Students Throughout a School Year: Longitudinal Naturalistic Study.

Journal Article JMIR Public Health Surveill · January 4, 2022 BACKGROUND: The Wellness Environment app study is a longitudinal study focused on promoting health in college students. OBJECTIVE: The two aims of this study were (1) to assess physical activity (PA) variation across the days of the week and throughout the ... Full text Link to item Cite

Daily wellness behaviors in college students across a school year.

Journal Article J Am Coll Health · 2022 Objective: To establish the prevalence of mood and wellness behaviors in college students across a school year. Methods: 1,554 college students (69.4% female; average age 18.8 years) were followed with daily surveys on wellness behaviors for the school yea ... Full text Link to item Cite

Music-Based Mentoring and Academic Improvement in High-Poverty Elementary Schools

Journal Article Journal of Youth Development · January 1, 2022 Recent research links disparities in children’s language-related brain function to poverty and its correlates. Such disparities are hypothesized to underlie achievement gaps between students from low-income families and more advantaged peers. Interventions ... Full text Cite

Investigating Relationships between Negative Peer Interactions, Polygenic Influences on Pubertal Timing, and Depression Symptoms Across Sexes

Conference GENETIC EPIDEMIOLOGY · 2022 Cite

Methylomic Investigation of Problematic Adolescent Cannabis Use and Its Negative Mental Health Consequences.

Journal Article J Am Acad Child Adolesc Psychiatry · December 2021 OBJECTIVE: The impact of adolescent cannabis use is a pressing public health question owing to the high rates of use and links to negative outcomes. This study considered the association between problematic adolescent cannabis use and methylation. METHOD: ... Full text Link to item Cite

Impact of the COVID-19 pandemic on substance use among adults without children, parents, and adolescents.

Journal Article Addict Behav Rep · December 2021 Impact of the COVID-19 pandemic on alcohol and illicit substance use among adults without children, parents, and adolescents was investigated through two studies with five samples from independent ongoing U.S. longitudinal studies. In Study 1, 931 adults w ... Full text Open Access Link to item Cite

Frequent teenage cannabis use: Prevalence across adolescence and associations with young adult psychopathology and functional well-being in an urban cohort.

Journal Article Drug Alcohol Depend · November 1, 2021 BACKGROUND: Amidst cannabis legalization efforts and laws, we do not fully understand how the youngest frequent cannabis users fare during young adulthood. This study aims to 1) examine the prevalence of cannabis use during adolescence, and 2) investigate ... Full text Link to item Cite

36.3 PERSONALITY TRAITS AND COPING DURING THE COVID-19 PANDEMIC

Conference Journal of the American Academy of Child & Adolescent Psychiatry · October 2021 Full text Cite

Continuity of Genetic Risk for Aggressive Behavior Across the Life-Course.

Journal Article Behav Genet · September 2021 We test whether genetic influences that explain individual differences in aggression in early life also explain individual differences across the life-course. In two cohorts from The Netherlands (N = 13,471) and Australia (N = 5628), polygenic scores (PGSs ... Full text Link to item Cite

A Digital Therapeutic Intervention Delivering Biofeedback for Panic Attacks (PanicMechanic): Feasibility and Usability Study (Preprint)

Preprint · August 17, 2021 Full text Cite

Digital Phenotype for Childhood Internalizing Disorders: Less Positive Play and Promise for a Brief Assessment Battery.

Journal Article IEEE J Biomed Health Inform · August 2021 Childhood internalizing disorders, like anxiety and depression, are common, impairing, and difficult to detect. Universal childhood mental health screening has been recommended, but new technologies are needed to provide objective detection. Instrumented m ... Full text Link to item Cite

Childhood Gun Access, Adult Suicidality, and Crime.

Journal Article Pediatrics · August 2021 OBJECTIVES: To test the associations of childhood domestic gun access with adult criminality and suicidality. METHODS: Analyses were based on a 20+ year prospective, community-representative study of 1420 children, who were assessed up to 8 times during ch ... Full text Link to item Cite

Genetic association study of childhood aggression across raters, instruments, and age.

Journal Article Transl Psychiatry · July 30, 2021 Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from multiple assessors were included. ... Full text Link to item Cite

Psychiatry and Deaths of Despair.

Journal Article JAMA Psychiatry · July 1, 2021 Full text Link to item Cite

Associations of Childhood and Adolescent Depression With Adult Psychiatric and Functional Outcomes.

Journal Article J Am Acad Child Adolesc Psychiatry · May 2021 OBJECTIVE: Depression is common, impairing, and the leading cause of disease burden in youths. This study aimed to identify the effects of childhood/adolescent depression on a broad range of longer-term outcomes. METHOD: The analysis is based on the prospe ... Full text Link to item Cite

Prevalence and Childhood Precursors of Opioid Use in the Early Decades of Life.

Journal Article JAMA Pediatr · March 1, 2021 IMPORTANCE: Opioid use disorder and opioid deaths have increased dramatically in young adults in the US, but the age-related course or precursors to opioid use among young people are not fully understood. OBJECTIVE: To document age-related changes in opioi ... Full text Link to item Cite

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.

Journal Article Addict Biol · January 2021 Eating disorders and substance use disorders frequently co-occur. Twin studies reveal shared genetic variance between liabilities to eating disorders and substance use, with the strongest associations between symptoms of bulimia nervosa and problem alcohol ... Full text Link to item Cite

Impact of COVID-19 Pandemic on College Student Mental Health and Wellness.

Journal Article J Am Acad Child Adolesc Psychiatry · January 2021 OBJECTIVE: To test the impact of the coronavirus disease 2019 (COVID) pandemic on the emotions, behavior, and wellness behaviors of first-year college students. METHOD: A total of 675 first-year university students completed a full assessment of behavioral ... Full text Link to item Cite

Personality trait predictors of adjustment during the COVID pandemic among college students.

Journal Article PLoS One · 2021 Personality traits have been found to be related to a variety of health outcomes. The aim of this study was to examine how personality traits were associated with adjustment to the COVID pandemic in college students. The sample included 484 first-year univ ... Full text Link to item Cite

Longitudinal associations of trauma exposure with disordered eating: Lessons from the Great Smoky Mountains Study.

Journal Article Eat Disord · 2021 Disordered eating is prevalent among trauma survivors, yet little is known about mechanisms underlying this relation. We explored cross-sectional and longitudinal associations of trauma exposure and posttraumatic stress disorder symptoms (PTSD) with disord ... Full text Link to item Cite

Correction: Personality trait predictors of adjustment during the COVID pandemic among college students.

Journal Article PLoS One · 2021 [This corrects the article DOI: 10.1371/journal.pone.0248895.]. ... Full text Link to item Cite

A large-scale genome-wide association study meta-analysis of cannabis use disorder.

Journal Article Lancet Psychiatry · December 2020 BACKGROUND: Variation in liability to cannabis use disorder has a strong genetic component (estimated twin and family heritability about 50-70%) and is associated with negative outcomes, including increased risk of psychopathology. The aim of the study was ... Full text Link to item Cite

Ecological Momentary Assessment of Physical Activity and Wellness Behaviors in College Students Throughout a School Year: Longitudinal Naturalistic Study (Preprint)

Preprint · October 29, 2020 Full text Cite

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium.

Journal Article Mol Psychiatry · August 2020 To provide insights into the biology of opioid dependence (OD) and opioid use (i.e., exposure, OE), we completed a genome-wide analysis comparing 4503 OD cases, 4173 opioid-exposed controls, and 32,500 opioid-unexposed controls, including participants of E ... Full text Link to item Cite

Associations of Despair With Suicidality and Substance Misuse Among Young Adults.

Journal Article JAMA Netw Open · June 1, 2020 IMPORTANCE: Deaths of despair is a term that has recently been used to describe the increases in premature mortality from suicides, drug overdoses (particularly from opiates), and alcohol-related liver disease among US adults. Despite the use of the term d ... Full text Link to item Cite

Human Capital and Voting Behavior across Generations: Evidence from an Income Intervention

Journal Article American Political Science Review · May 1, 2020 Despite clear evidence of a sharp income gradient in voting participation, it remains unclear whether income truly causes voting. In this article, we investigate how exogenous increases in unearned income affect voting in U.S. elections for two generations ... Full text Cite

Error in Table.

Journal Article JAMA Netw Open · May 1, 2020 Full text Link to item Cite

Adolescent depression and subsequent earnings across early to middle adulthood: a 25-year longitudinal cohort study.

Journal Article Epidemiol Psychiatr Sci · April 29, 2020 AIMS: The few available studies on early-onset depression and future earnings offer ambiguous findings, and potential sources of heterogeneity are poorly understood. We examined the differences in adult earnings of males and females with and without a hist ... Full text Link to item Cite

Young Adolescents' Digital Technology Use, Perceived Impairments, and Well-Being in a Representative Sample.

Journal Article J Pediatr · April 2020 OBJECTIVE: To examine the cross-sectional associations between young adolescents' access, use, and perceived impairments related to digital technologies and their academic, psychological, and physical well-being. STUDY DESIGN: There were 2104 adolescents ( ... Full text Link to item Cite

Editorial: One Reason Why Not.

Journal Article J Am Acad Child Adolesc Psychiatry · February 2020 After declining modestly from 1999 to 2007, death rates from suicide in adolescents increased 56% from 2007 to 2016.1 Suicide continues to be the second leading cause of death in this age group. Risk factors for suicidal thoughts and behavior in adolescent ... Full text Link to item Cite

Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment.

Journal Article Biodemography Soc Biol · 2020 Persons with high temporal discounting tend to value immediate gratification over future gains. Low self-reported lifespan (SRL)-an individual's assessment of a relatively short future lifespan-concentrates in low-income populations and may reflect high te ... Full text Link to item Cite

Physical Activity And Its Association With Other Wellness And Risk Behaviors From A College Sample

Conference MEDICINE & SCIENCE IN SPORTS & EXERCISE · 2020 Cite

Genetic correlations of psychiatric traits with body composition and glycemic traits are sex- and age-dependent.

Journal Article Nat Commun · December 18, 2019 Body composition is often altered in psychiatric disorders. Using genome-wide common genetic variation data, we calculate sex-specific genetic correlations amongst body fat %, fat mass, fat-free mass, physical activity, glycemic traits and 17 psychiatric t ... Full text Link to item Cite

Early Pubertal Timing and Testosterone Associated With Higher Levels of Adolescent Depression in Girls.

Journal Article J Am Acad Child Adolesc Psychiatry · December 2019 OBJECTIVE: The prevalence of depression increases dramatically during puberty in girls. Earlier work in this sample reported that the sex steroids estradiol and testosterone were associated with increased depression in girls. Using three additional data wa ... Full text Link to item Cite